Patent application number | Description | Published |
20090131919 | Implantable medical device - The present invention comprises a modular, implantable medical device comprising a body portion capable of receiving a treatment device that accesses a patient's inner physiology while communicating with a device external to the patient. The body portion further includes a first skirt and a second skirt that surround the treatment device at its junction with the body portion. Both skirts are designed to gradually affix themselves into the surrounding tissues of the patient's body during an initial phase of healing. The first skirt is designed to separate from the device at a lower force than the second skirt such that during removal, the device and second skirt can be detached as a unit from patient's skin and first skirt without excessive force or trauma and the first skirt remains attached to the patient's skin as a permanent implant. | 05-21-2009 |
20100016835 | MODULAR IMPLANTABLE MEDICAL DEVICE - The present invention is a modular implantable medical device that is used deliver materials or energy into a patient's physiology, or from one region of a patient's physiology to another. The device includes a port element with a passageway therethrough for directing and anchoring a conduit element in a desired location. Both elements can be adjusted during placement to maximize the safety, comfort, and efficacy of use. In one embodiment, the port element is comprised of two components such that the passage way is formed after the components are assembled. This modularity enables a large diameter section of the conduit to be advanced past the port location, and the port to be assembled about a smaller proximal section of the conduit, thereby establishing full contact between the port and conduit elements to anchor the device in an optimal position. | 01-21-2010 |
20120059327 | MODULAR IMPLANTABLE MEDICAL DEVICE - The present invention is an implantable medical device that is used deliver materials or energy into a patient's physiology, or from one region of a patient's physiology to another. The device includes a port element with a passageway therethrough for directing and anchoring a conduit element in a desired location. The implantable port stabilizes an elongated conduit within human physiology for long-term use, and includes a support passageway formed through the port and extending between an upper surface and a lower surface of the port, wherein the support passageway is sized and shaped for receiving the elongated conduit slideably inserted therethrough. The device includes a tissue ingrowth scaffold fixedly disposed on at least a portion of at least one surface of the implantable port for positioning in contact with adjacent tissue. | 03-08-2012 |
Patent application number | Description | Published |
20110176638 | Method and Apparatus for Adjusting a Symbol Decision Threshold at a Receiver in a Communication Network - A method and apparatus for adjusting a symbol decision threshold at a receiver in a communication network enables the receiver to be adapted to more correctly receive symbols as transmitted by a transmitter. In one embodiment, a received bit imbalance is detected by a receiver prior to error correction and after error correction to determine whether an error component of the received signal contains larger numbers of ones or larger numbers of zeros. Where the transmitter scrambles the signal prior to transmission, the receiver will also scramble the signal after error correction and prior to counting the number of zeros or ones. Any imbalance between the number of transmitted and received ones or zeros is used as feedback to adjust threshold values used by detectors to fine tune the manner in which the receiver interprets incoming signals. | 07-21-2011 |
20110222637 | Method and Apparatus for Reducing the Contribution of Noise to Digitally Sampled Signals - A method and apparatus for reducing the contribution of noise to digitally sampled signals includes a statistical processor and a slope limiter. The statistical processor determines an average value (mean and/or standard deviation) of the filtered signal which is used to determine a slope limit corresponding to an expected maximum first derivative value of a target signal frequency. This slope limit is applied to constrain the output of an analog to digital converter, to prevent the output of the analog to digital converter from exceeding this maximum rate of rise or fall. By constraining the output of the analog to digital converter, it is possible to digitally sample analog signals without first utilizing an anti-aliasing filter, since the post processing of the digitally sampled signals limits the contribution of the higher frequency components of the signal to thereby enable a fully digital sampling and filtering circuit to be provided for receiving signals. | 09-15-2011 |
20140103980 | Method and Apparatus for Reducing the Contribution of Noise to Digitally Sampled Signals - The contribution of noise to digitally sampled signals is reduced using a statistical processor and a slope limiter. The statistical processor determines an average value (mean and/or standard deviation) of the filtered signal which is used to determine a slope limit corresponding to an expected maximum first derivative value of a target signal frequency. This slope limit is applied to constrain the output of an analog to digital converter, to prevent the output of the analog to digital converter from exceeding this maximum rate of rise or fall. By constraining the output of the analog to digital converter, it is possible to digitally sample analog signals without first utilizing an anti-aliasing filter, since the post processing of the digitally sampled signals limits the contribution of the higher frequency components of the signal to thereby enable a fully digital sampling and filtering circuit to be provided for receiving signals. | 04-17-2014 |
Patent application number | Description | Published |
20090325195 | POLYCLONAL-MONOCLONAL ELISA ASSAY FOR DETECTING N-TERMINUS PRO-BNP - A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP. | 12-31-2009 |
20100248275 | METHODS FOR PREDICTING OUTCOME IN TRAUMATIC BRAIN INJURY - The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily fluids. Utilization of such methods improves diagnosis and treatment of patients suffering from traumatic brain injury, thus potentially minimizing and/or eliminating long-term adverse effects in these patients. | 09-30-2010 |
20120107848 | POLYCLONAL-MONOCLONAL ELISA ASSAY FOR DETECTING N-TERMINUS PRO-BNP - A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP. | 05-03-2012 |
20120149042 | METHODS FOR PREDICTING OUTCOME IN TRAUMATIC BRAIN INJURY - The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily fluids. Utilization of such methods improves diagnosis and treatment of patients suffering from traumatic brain injury, thus potentially minimizing and/or eliminating long-term adverse effects in these patients. | 06-14-2012 |