Patent application number | Description | Published |
20080299047 | Method for preparation of water-soluble and dispersed iron oxide nanoparticles and application thereof - The present invention relates to a process for preparing water-soluble and dispersed iron oxide (Fe | 12-04-2008 |
20110014293 | CLEAVAGE KIT, AND GENE THERAPY BY USING THE SAME AND NUCLEIC ACID CLEAVAGE DETECTION APPARATUS - A nucleic acid cleavage kit is used to cleave a target nucleic acid. The nucleic acid cleavage kit includes a carrier, an oligonucleotide, and a nucleic acid cleavage agent. The oligonucleotide recognizes at least partial sequence of the target nucleic acid. Then, the nucleic acid cleavage agent cleaves the target nucleic acid. A nucleic acid cleavage detection apparatus including the nucleic acid cleaving kit and a gene therapy by administering the nucleic acid cleavage kit are also disclosed. | 01-20-2011 |
20120027861 | Nano-carrier, complex of anticancer drug and nano-carrier, pharmaceutical composition thereof, method for manufacturing the complex, and method for treating cancer by using the pharmaceutical composition - The present invention relates to a nano-carrier for an anticancer drug, which comprises: a metal nanoparticle; and a polynucleotide for connecting with an anticancer drug having a pyrimidine group or a purine group, wherein the polynucleotide connects to a surface of the metal nanoparticle, and the anticancer drug binds to the polynucleotide through the pyrimidine group or the purine group. In addition, the present invention also provides a complex of an anticancer drug and a nano-carrier, a pharmaceutical composition thereof, a method for manufacturing the complex, and a method for treating a cancer by using the pharmaceutical composition. | 02-02-2012 |
20120116184 | PERIPHERAL PHYSIOLOGY INSPECTION APPARATUS AND PERIPHERAL AUXILIARY APPARATUS OF SMART PHONE - A peripheral physiology inspection apparatus of smart phone is connected with a smart phone having a TRRS socket for performing a physiology inspection. The peripheral physiology inspection apparatus includes: an inspection main body including a first physiology sensing unit; a plurality of signal transmission units; and a TRRS terminal for connecting with the inspection main body via the signal transmission units. The TRRS terminal is corresponding to the TRRS socket for allowing the inspection main body to be electrically connected to the smart phone, thereby enabling the smart phone to analyze and process physiology signals inspected by and delivered from the inspection main body. | 05-10-2012 |
20120116241 | PORTABLE ASTHMA DETECTION DEVICE AND STAND-ALONE PORTABLE ASTHMA DETECTION DEVICE - The present invention relates to a portable asthma detection device and a stand-alone portable asthma detection device. The portable asthma detection device includes a housing; a gas detection module comprising a turbine and a mini airflow sensor; a gas introducing tube; and a signal delivery unit. In addition, the stand-alone portable asthma detection device includes a housing; a gas detection module comprising a turbine and a mini airflow sensor; a gas introducing tube; at least one input unit; at least one display unit; and at least one delivery unit. Thus, the detection of breathing condition can be performed anytime and anywhere by using the portable asthma detection device and stand-alone device, and then the efficiency of monitor and management of asthma can be improved. | 05-10-2012 |
20120123107 | NUCLEIC ACID CLEAVAGE COMPLEX AND METHOD FOR USING THE SAME - A nucleic acid cleavage complex is disclosed, which includes: a nanoparticle, a nucleic acid cleavage reagent, and a polynucleotide chain specifically recognizing a sequence of a target nucleic acid and having a first terminal and a second terminal opposite to the first terminal, wherein the first terminal is connected to the nanoparticle, the second terminal is connected to the nucleic acid cleavage reagent, and the first terminal sequence and the second terminal sequence are base-paired to make the polynucleotide chain form a hairpin. Also, a method for using the nucleic acid cleavage complex is also disclosed. | 05-17-2012 |
20120209124 | BREAST HEALTH CARE DEVICE - The present invention relates to a breast health care device, which comprises: a main body, which comprises at least one cover portion; and at least one node module, which is disposed on the cover portion. The node module comprises a light-emitting unit, a photo detector, or the combination thereof, wherein the light-emitting unit provides a light of predetermined wavelength to a breast tissue, and the photo detector detects a first signal generated from the breast tissue. Thus, users can directly achieve detection for the health condition of breasts by wearing the bra of the disclosed breast health care device of the present invention, and the disclosed health care device can transmit the detection results to an external health-care platform such as hospitals or medical centers immediately. | 08-16-2012 |
20120282327 | PHOSPHATE-CONTAINING NANOPARTICLE DELIVERY VEHICLE - A phosphate-containing nanoparticle delivery vehicle includes nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release. | 11-08-2012 |
20120289712 | PHOSPHATE-CONTAINING NANOPARTICLE DELIVERY VEHICLE - A phosphate-containing nanoparticle delivery vehicle includes a nanoparticle, an active ingredient, and a phosphodiester moiety connecting the nanoparticle and the active ingredient and forms a prodrug. The nanoparticle delivery vehicle achieves the function of increasing hydrophilicity of the active ingredient and specificity against tumor cells. Advantages of the nanoparticle material include biocompatibility, magnetism and/or controllable drug release. | 11-15-2012 |
20130053660 | Blood Component Detection Device - The present invention relates to a blood component detection unit, which comprises: a capsule body having a first surface; a needle array including a plurality of needles, each of the needles have an opening and an inner hollow space, and each of the needles protrudes out of the first surface; a detection chamber disposed inside the capsule body and connected with the inner hollow space; a sensing chip disposed inside the capsule body; and a plurality of sensing elements disposed on the sensing chip. | 02-28-2013 |
20130070246 | OPTICAL DETECTION APPARATUS - An optical detection apparatus used for detecting a tissue includes a light-emitting unit, a spectroscopic unit and a light-sensing array. The light-emitting unit emits light entering into the tissue. The spectroscopic unit receives the light outputted from the tissue and divides the received light into a plurality of rays with different wavelengths. The light-sensing array senses the rays outputted from the spectroscopic unit so as to generate an array spectrum. By the spectroscopic unit, the detection of the rays of multiple wavelengths can be performed without using plural light-emitting diodes for emitting light of different wavelengths. Besides, the user can perceive the detection result (e.g. the location of the abnormal tissue) intuitively by integrating the light-sensing array and the spectroscopic unit. | 03-21-2013 |
20130171258 | Pharmaceutical composition for elevating radio-sensitivity of cancer cells, pharmaceutical composition for detecting cancer cells with radio-sensitivity, and detection method thereof - The present invention relates to a pharmaceutical composition for elevating radiation-sensitivity of cancer cells, which comprises: a nanoparticle containing with a first element, which is iron, copper, or the combination thereof; and a pharmaceutically acceptable carrier, wherein the nanoparticle is a metal nanoparticle, an alloy nanoparticle, or a metal nanoparticle with core-shell structure, and the size of the nanoparticle is under a controllable range of 3 nm to 150 nm. In addition, the present invention provides a detection method to detect radiation-sensitivity of the cancer cells through different modalities such as CT or MRI due to its native high CT number and magnetic property. Furthermore, the present invention provides a pharmaceutical composition for elevating radiation-sensitivity of the cancer cells through preferential uptake of the nanoparticle, in order to enhance the radiation-sensitivity of the cancer cells and improve the efficiency of radiation therapy to the cancer cells. | 07-04-2013 |
20130236507 | Method for treating cancer by using Fe-containing alloy particles - A method for treating a cancer is disclosed, which comprises: administering an effective amount of Fe-containing alloy particles to a subject in need, wherein a material of each Fe-containing alloy particle is an alloy comprising a first metal of Fe and a second metal. | 09-12-2013 |
20130236519 | Oral health care material and teeth cleaning agent composition - An oral health care material and a teeth cleaning agent composition are disclosed. The oral health care material is made of zinc oxide grains, where each is selected from the group consisting of zinc oxide crystalline nanograins, zinc oxide nanorods, zinc oxide hollow fibers, and a mixture thereof, wherein the diameter of each of the zinc oxide crystalline nanograins is 25 nm-200 nm, the cross-sectional diameter of each of the zinc oxide nanorods is 50 nm-1000 nm, the cross-sectional diameter of each of the zinc oxide hollow fibers is 500 nm-3 μm and its nanograin size is 20 nm-100 nm. | 09-12-2013 |
20130236548 | Method for treating cancer by using Fe-based particles - A method for treating a cancer is disclosed, which comprises: administering an effective amount of Fe-based particles to a subject in need, wherein the Fe-based particles have core-shell structures. Herein, each Fe-based particle of the present invention comprises: an Fe elemental core with zero valent irons; and a covering layer formed on partial or whole surface of the Fe elemental core, wherein a material of the covering layer is a metal, a metal doped with dopants, a metal alloy, a polymer, carbon, a metal oxide or a nonmetal oxide, and the shape of the Fe-based particles is a rod, a sphere, a cubic or a dumbbell, with the proviso that the metal is not Au. | 09-12-2013 |
20130281808 | BLOOD COMPONENT DETECTION DEVICE - The present invention relates to a blood component detection unit, which comprises: a capsule body having a first surface; a needle array including a plurality of needles, each of the needles have an opening and an inner hollow space, and each of the needles protrudes out of the first surface; a detection chamber disposed inside the capsule body and connected with the inner hollow space; a sensing chip disposed inside the capsule body; and a plurality of sensing elements disposed on the sensing chip. | 10-24-2013 |
20130337071 | RADIOFREQUENCY-INDUCED SYNCHRONIZATION OF IN SITU HYPERTHERMIA AND CHEMOTHERAPY VIA MAGNETIC-NANOCONJUGATES - The present invention relates to a magnetic nanoparticle for tumor therapy, comprising: a magnetic core; a shell encapsulating a surface of the magnetic core, wherein the shell is made of a polymer with carboxylic groups; a poly-nucleotide chain connected to a surface of the shell; an anti-tumor drug connected to the poly-nucleotide chain, wherein the anti-tumor drug comprises at least one functional group, and each of the functional group is independently a pyrimidine group or a purine group; and an antibody connected to the shell, wherein the antibody identifies a target tumor. In addition, the present invention further provides a method for manufacturing the magnetic nanoparticles for tumor therapy and a pharmaceutical composition containing the magnetic nanoparticles. Accordingly, the magnetic nanoparticle for tumor therapy of the present invention can achieve effective treatment of tumor by synergistic effects between hyperthermia and targeted chemotherapy. | 12-19-2013 |
20140056948 | HARD TISSUE REGENERATION MATERIAL AND METHOD FOR MANUFACTURING THE SAME - A hard tissue regeneration material and a method for manufacturing the same are disclosed. The hard tissue regeneration material of the present invention comprises: ZnO particles selected from the group consisting of crystallized ZnO particles, crystallized ZnO nanorods, nano-ZnO hollow fibers, and a combination thereof; and at least one selected from the group consisting of polycarboxylate cement, glass ionomer cements, and collagen. | 02-27-2014 |
20140093871 | Method for detecting mitochondria alterations - The present invention relates to a method for detecting mitochondria alterations, which comprises the following steps: (A) providing a separation element and a sample; (B) mixing the separation element and the sample, wherein a detecting sample is obtained through the binding of a DNA fragment on the separation element to mitochondrial DNA in the sample; (C) dividing the detecting sample into a comparison group and a detection group; (D) adding an amplification solution into the comparison group and the detection group respectively to begin a DNA amplified reaction, and further adding a restriction enzyme into the detection group, wherein the amplification solution comprises a labeling reagent and a primer pair; and (E) detecting amounts of the labeling reagent in the comparison group and the detection group respectively after the DNA amplified reaction. | 04-03-2014 |
20140161891 | COMPOSITION OF PI3K INHIBITOR AND USE THEREOF - The present invention is related to a composition of PI3K inhibitor, comprising: 0.01˜10 mg of PI3K inhibitor; 10˜500 mg of poly(lactic-co-glycolic acid) (PLGA) which is encapsulated onto the surface of the PI3K inhibitor and the surface is non-modified by a modifier; and the composition has a size of 10˜1000 nm. Thereby, an excellent effect on suppressing the growth of tumor cells will be achieved by the encapsulation of PI3K inhibitor into PLGA nanomaterials without any modifier on its surface, the optimization of a ratio of PI3K inhibitor to PLGA, and the accordingly slow release of the composition. | 06-12-2014 |