Patent application number | Description | Published |
20120157445 | Cognitive Function - Provided herein are methods, drug formulations, and dosing regimens for improving cognitive function in a normal or cognitively impaired subject. For instance, methods provided herein comprise administering a GABA | 06-21-2012 |
20120251989 | APPARATUS, SYSTEM, AND METHOD FOR MODULATING CONSOLIDATION OF MEMORY DURING SLEEP - Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement/relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep. | 10-04-2012 |
20120283502 | ULTRASOUND NEUROMODULATION TREATMENT OF DEPRESSION AND BIPOLAR DISORDER - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat depression, bipolar disorder, and other mood disorders. Also disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to affect the mood or emotional state of a subject or user. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Potentiation (LTP) or Long-Term Depression (LTD) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation. | 11-08-2012 |
20130144192 | ULTRASOUND NEUROMODULATION TREATMENT OF ANXIETY (INCLUDING PANIC ATTACKS) AND OBSESSIVE-COMPULSIVE DISORDER - Disclosed are methods and systems and methods for non-invasive neuromodulation using ultrasound to treat anxiety (including panic attacks) and Obsessive-Compulsive Disorder. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation. | 06-06-2013 |
20130190556 | APPARATUS, SYSTEM, AND METHOD FOR MODULATING CONSOLIDATION OF MEMORY DURING SLEEP - Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. For example, described herein are systems, methods and devices to enhance a user's cognitive function in such areas as memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. In some variations the machine records ambient sensory inputs during awake acquisition or reinforcement/relearning and replays all or an extracted form of the ambient sensory stimuli a specified portion of the user's sleep. | 07-25-2013 |
20130197401 | OPTIMIZATION OF ULTRASOUND WAVEFORM CHARACTERISTICS FOR TRANSCRANIAL ULTRASOUND NEUROMODULATION - The present invention relates to methods and systems for achieving effective neuromodulation by transcranial ultrasound (bioTU). Embodiments of the invention include methods and systems for selecting, generating, and delivering transcranial ultrasound to the brain of a living subject. Methods and systems are described for determining the effect of bioTU on brain function. Certain embodiments of the present invention include methods and systems for measuring at least one quantifiable metric of brain activity, cognitive function, or physiology in order to optimize the ultrasound waveforms delivered. In an embodiment, the invention uses a closed-loop design to iteratively improve the effectiveness of bioTU waveforms delivered. | 08-01-2013 |
20140057232 | APPARATUS, SYSTEM, AND METHOD FOR MODULATING CONSOLIDATION OF MEMORY DURING SLEEP - Devices, systems and methods to modify memory and/or cognitive function by delivering a sensory stimulus paired with learned material at opportune physiological periods during sleep. Described herein are systems, methods and devices to enhance a user's cognitive function in memorization and learning. A machine (e.g., a system or device) may be used to identify opportune periods of the sleep cycle and to deliver a stimulus during specific phases of the sleep cycle to facilitate or interrupt memory consolidation. The machine may record ambient sensory inputs during awake acquisition or reinforcement/relearning and replay all or an extracted form of the ambient sensory stimuli during a specified portion of the user's sleep. A stimulus may be delivered to a user to affect brain activity during sleep to modulate the phase of a user's sleep, quality of sleep, and/or quality or intensity of brain rhythms during a particular phase of sleep. | 02-27-2014 |
20140148872 | WEARABLE TRANSDERMAL ELECTRICAL STIMULATION DEVICES AND METHODS OF USING THEM - Described herein are devices, systems, and methods for transdermal electrical stimulation. Devices described herein can include self-contained, lightweight, and wearable components. The devices include a primary unit including a first transdermal electrode and a secondary unit including a second transdermal electrode. The device can be capable of wireless communication. The primary unit and secondary unit are placed at two locations on the skin of a user, for example on the head or neck of a user. The first and second transdermal electrodes are electrically connected. Electrical stimulation is driven between the two electrodes. The electrical stimulation induces a cognitive effect in a user of the device. | 05-29-2014 |
20140194726 | Ultrasound Neuromodulation for Cognitive Enhancement - Disclosed are methods and systems for non-invasive neuromodulation using ultrasound for cognitive enhancement. Cognitive enhancement can be used for mitigation of abnormal conditions such as Alzheimer's Disease, Parkinson's Disease or stroke, or for enhancement in a normal individual. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, mechanical perturbation, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation. | 07-10-2014 |
20140211593 | METHOD AND SYSTEM FOR DIRECT COMMUNICATION - Information is communicated to an individual by directing an acoustic signal transcranially to a target region in the brain. The target region is stimulated to produce a cognitive effect, and the cognitive effect is modulated or encoded to carry the desired information. | 07-31-2014 |
20150088224 | WEARABLE TRANSDERMAL ELECTRICAL STIMULATION DEVICES AND METHODS OF USING THEM - Apparatuses (e.g., devices, systems), and methods for transdermal electrical stimulation (TES). Apparatuses described herein can be self-contained, lightweight, and wearable. The apparatus may include a primary unit (TES stimulator) and an electrode portion that includes a first transdermal electrode and a second transdermal electrode and mates with the TES stimulator. The first electrode and secondary electrode are placed at two locations on the skin of a user, for example on the head and/or neck of a user. Electrical stimulation driven between the two electrodes may induce a cognitive effect in a user of the device. | 03-26-2015 |