Dalgleish
Andrew Robert Dalgleish, Victoria AU
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20110184831 | AN ITEM RECOMMENDATION SYSTEM - An item recommendation process, executed by a computer system, including: | 07-28-2011 |
Angus Dalgleish, London GB
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20160106832 | TREATMENT OF CANCER WITH NALTREXONE - The present invention provides novel therapeutic applications of low dose naltrexone (LDN). Said applications have been determined in light of the discovery by the present inventors that naltrexone acts as an antagonist of Toll-like receptor 9 (TLR9), an innate immune receptor which elicits the production of inflammatory cytokines when agonized. Chronic inflammation and TLR9 overexpression are characteristics of a number of disorders, including certain cancers. Accordingly, the present invention provides novel uses of naltrexone in the treatment of a subject having a disorder characterised by TLR9 overexpression and/or overactivity of TLR9-mediated signalling. The present invention also provides novel uses of naltrexone in the supportive care of subject having a tumour/cancer, and methods of treating and providing supportive care to a subject, comprising the administration of naltrexone. | 04-21-2016 |
Angus Dalgleish, Cheam GB
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20130136757 | METHODS OF TREATING CANCER USING A COMBINATION OF AN IMMUNOMODULATORY COMPOUND AND AN ARTEMISININ OR A DERIVATIVE THEREOF - Provided herein are methods for treating cancers by administering immunomodulatory compounds in combination with artemisinin or a derivative thereof. In particular, methods for treating cancers by administering lenalidomide in combination with artemisinin or a derivative thereof are provided. | 05-30-2013 |
Angus Dalgleish, Cheaham Surrey GB
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20120263720 | Novel Therapeutic and Diagnostic Means - Disclosed is a method for treatment of HIV related diseases comprising targeting complexes between on the one hand the C5 domain of gp120 and on the other hand gp41 or the C2 domain of gp120. The complexes may be stabilised by administering compounds, such as antibodies, capable of directly interacting with and stabilising the complex, or by immunizing with C5 and gp41/C2 derived material so as to induce antibodies that bind to and stabilise the complex. | 10-18-2012 |
Angus G. Dalgleish, Cheam GB
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20120190110 | IMMUNOLOGICAL USES OF IMMUNOMODULATORY COMPOUNDS FOR VACCINE AND ANTI-INFECTIOUS DISEASE THERAPY - Methods of enhancing immune response to an immunogen in a subject are disclosed. Also disclosed are methods of reducing the sensitivity to an allergen in a subject. The methods comprise the administration of an immunomodulatory compound in specific dosing regimens that result in enhanced immune response or reduced sensitivity. | 07-26-2012 |
Angus G. Dalgleish, Surrey GB
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20100291102 | Therapeutic Agent - Anti-HLA and other antibodies are present in goat serum after injection of HIV antigenic material, and form the basis for a most surprisingly effective treatment of HIV, multiple sclerosis and other conditions. | 11-18-2010 |
20110086046 | Treatment of MS with goat serum - A serum composition from a goat immunised with HIV contains anti-HLA antibody and is suited for palliative improvement of the condition of an animal. | 04-14-2011 |
20120100156 | Therapeutic Agent - Anti-HLA and other antibodies are present in goat serum after injection of HIV antigenic material, and form the basis for a most surprisingly effective treatment of HIV, multiple sclerosis and other conditions. | 04-26-2012 |
20130195890 | TREATMENT OF MS WITH GOAT SERUM - A serum composition from a goat immunised with HIV contains anti-HLA antibody and is suited for palliative improvement of the condition of an animal. | 08-01-2013 |
Angus G. Dalgleish, London GB
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20130230600 | THERAPEUTIC AGENT - Anti-HLA and other antibodies are present in goat serum after injection of HIV antigenic material, and form the basis for a most surprisingly effective treatment of HIV, multiple sclerosis and other conditions. | 09-05-2013 |
20160002320 | THERAPEUTIC AGENT - Anti-HLA and other antibodies are present in goat serum after injection of HIV antigenic material, and form the basis for a most surprisingly effective treatment of HIV, multiple sclerosis and other conditions. | 01-07-2016 |
Angus George Dalgleish, Cheam GB
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20130171196 | Immunomodulatory Compounds for the Restoration of Vitamin D Sensitivity in Vitamin D Resistant Tumor Cells - Provided herein are methods of restoring vitamin D sensitivity in tumor cells that are vitamin D resistant. Also provided are methods of treating, preventing or managing cancer using an immunomodulatory compound in combination with a vitamin D agent. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods provided herein are also disclosed. | 07-04-2013 |
20150283124 | Immunomodulatory Compounds for the Restoration of Vitamin D Sensitivity in Vitamin D Resistant Tumor Cells - Provided herein are methods of restoring vitamin D sensitivity in tumor cells that are vitamin D resistant. Also provided are methods of treating, preventing or managing cancer using an immunomodulatory compound in combination with a vitamin D agent. Pharmaceutical compositions and single unit dosage forms suitable for use in the methods provided herein are also disclosed. | 10-08-2015 |
Angus George Dalgleish, London GB
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20090053170 | HUMAN PROSTATE CELL LINES IN CANCER TREATMENT - Combinations of cell lines are provided for allogeneic immunotherapy agents in the treatment of cancer. Cancer vaccines generally have been limited to the use of cells that contain at least some tumour specific antigens (“TSAs”) and/or tumour associated antigens (“TAAs”) having shared identity with antigens in a targeted tumour. In such cases, tumour cells often are utilised as a starting point on the premise that only tumour cells will contain TSAs or TAAs or relevance, and the tissue origins of the cells are matched to the tumour site in patients. A primary aspect of the invention is the use of immortalised normal, non-malignant cells, in combination with primary and/or metastatic tumour cells, as the basis of an allogeneic cell cancer vaccine. Normal cells do not posses TSAs or relevant concentrations of TAAs and hence it is surprising that normal cells are effective as anti-cancer vaccines when administered in combination with primary and/or metastatic tumour cells. More surprisingly, a three way combination of cells obtained from metastasised cells, non metastasised tumour and cells from a normal cell line provided good therapy. For prostate cancer, for example, a vaccine may be based on one or a combination of different immortalised normal cell lines derived from the prostate according to parameters described herein. The cell lines may be lethally irradiated with, for example, gamma irradiation at 50-300 Gy to ensure that they are replication incompetent prior to use. | 02-26-2009 |
20120164099 | USE OF HUMAN PROSTATE CELL LINES IN CANCER TREATMENT - This invention is concerned with agents for the treatment of primary, metastatic and residual cancer in mammals (including humans) by inducing the immune system of the mammal or human afflicted with cancer to mount an attack against the tumour lesion. In particular, the invention pertains to the use of whole-cells, derivatives and portions thereof with or without vaccine adjuvants and/or other accessory factors. More particularly, this disclosure describes the use of particular combinations of whole-cells and derivatives and portions thereof that form the basis of treatment strategy. | 06-28-2012 |
20130017222 | HUMAN PROSTATE CELL LINES IN CANCER TREATMENT - The invention provides methods and compositions for the treatment of primary, metastatic, and residual cancer in mammals, and more particularly, the use of materials such as whole cells and derivatives and portions thereof to stimulate the immune system to attack cancer. | 01-17-2013 |
Anni Dalgleish, Vero Beach, FL US
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20120069342 | MEMS Microdisplay Optical Imaging and Sensor Systems for Underwater Scattering Environments - An imaging or sensor system comprises a transmitter assembly, a receiver assembly and a control unit. The transmitter assembly defines an outgoing optical beam transmission path with respect to a target surface and the receiver assembly defines a return optical signal transmission path from the target surface. Each of the paths includes transmission through or reflection from at least one microdisplay device comprising a plurality of controllable elements for selective placement in a transmit mode for transmission of light along the transmission paths. A control unit selectively places the microdisplay device elements in the transmission mode. | 03-22-2012 |
20140204385 | MEMS MICRODISPLAY OPTICAL IMAGING AND SENSOR SYSTEMS FOR UNDERWATER AND OTHER SCATTERING ENVIRONMENTS - A sensing system is provided that includes a transmitter assembly with a light source and a microdisplay device, wherein the transmitter assembly defines an optical beam transmission path to provide illumination of a substantially one-dimensional (1D) region of a target area, the microdisplay device comprising a plurality of controllable elements for causing the illumination to be a substantially 1D pattern of light along the 1D region. The system further includes a receiver assembly for defining a return optical signal transmission path from the 1D region and collecting return optical signals from the 1D region. The system also includes a processing component for generating sensor information associated with the 1D region by processing the return optical signals from the 1D region with return optical signals from adjacent 1D regions using a distributed compressive sensing (DCS) technique. | 07-24-2014 |
Douglas G. Dalgleish, Guelph CA
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20090311329 | CASEIN MICELLES FOR NANOENCAPSULATION OF HYDROPHOBIC COMPOUNDS - The present invention relates to the field of food technology and delivery of hydrophobic biologically active compounds, particularly nutrients, via food products and beverages. In particular the present invention provides isolated casein micelles useful for the encapsulation of hydrophobic nutrients, therapeutic and cosmetic compounds, compositions thereof and methods of preparing the micelles. | 12-17-2009 |
20150231157 | CASEIN MICELLES FOR NANOENCAPSULATION OF HYDROPHOBIC COMPOUNDS - The present invention relates to the field of food technology and delivery of hydrophobic biologically active compounds, particularly nutrients, via food products and beverages. In particular the present invention provides isolated casein micelles useful for the encapsulation of hydrophobic nutrients, therapeutic and cosmetic compounds, compositions thereof and methods of preparing the micelles. | 08-20-2015 |
Fraser Dalgleish, Vero Beach, FL US
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20080218821 | Method and Apparatus for Synchronous Laser Beam Scanning - A scanner system. The system includes a mirror assembly having multiple reflective surfaces arranged to form one polygonal shape about an axis. A plurality of the multiple surfaces are each positionable to reflect radiation propagating from the source at a reflective angle and a position on the reflective surface to direct the radiation along a transmit path. When one reflective surface is so positioned, another surface is positioned to receive and reflect radiation along a detector signal path for processing. According to a related method for acquiring image data a mirror assembly is provided with multiple reflective surfaces sequentially arranged to form a polygonal shape about an axis. A beam of radiation is reflected from a first of the reflective surfaces and along a path in a first direction to a target region and a return signal propagates along the path in a second direction away from the target region. A portion of the return signal is reflected from a surface of a second of the reflective surfaces of the mirror assembly and along a path to a detector. | 09-11-2008 |
20120069342 | MEMS Microdisplay Optical Imaging and Sensor Systems for Underwater Scattering Environments - An imaging or sensor system comprises a transmitter assembly, a receiver assembly and a control unit. The transmitter assembly defines an outgoing optical beam transmission path with respect to a target surface and the receiver assembly defines a return optical signal transmission path from the target surface. Each of the paths includes transmission through or reflection from at least one microdisplay device comprising a plurality of controllable elements for selective placement in a transmit mode for transmission of light along the transmission paths. A control unit selectively places the microdisplay device elements in the transmission mode. | 03-22-2012 |
20140204385 | MEMS MICRODISPLAY OPTICAL IMAGING AND SENSOR SYSTEMS FOR UNDERWATER AND OTHER SCATTERING ENVIRONMENTS - A sensing system is provided that includes a transmitter assembly with a light source and a microdisplay device, wherein the transmitter assembly defines an optical beam transmission path to provide illumination of a substantially one-dimensional (1D) region of a target area, the microdisplay device comprising a plurality of controllable elements for causing the illumination to be a substantially 1D pattern of light along the 1D region. The system further includes a receiver assembly for defining a return optical signal transmission path from the 1D region and collecting return optical signals from the 1D region. The system also includes a processing component for generating sensor information associated with the 1D region by processing the return optical signals from the 1D region with return optical signals from adjacent 1D regions using a distributed compressive sensing (DCS) technique. | 07-24-2014 |
20150052991 | SINGLE BEAM/DETECTOR OPTICAL REMOTE CROSS- FLOW SENSOR - System and method for remotely sensing the cross-flow orientation of a fluid (including a gaseous fluid) over an extended range. A Fourier transform of beam wander of a single beam can be used to determine the orientation of the flow field. Many applications depend upon accurate flow orientation data to provide correct information such as, for example, citing of turbines on wind farms and atmospheric/ocean weather prediction. | 02-26-2015 |
Martin Dalgleish, Glasgow GB
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20140013224 | AUDIO SYSTEM AND AUDIO SYSTEM LIBRARY MANAGEMENT METHOD - An audio system is provided, the audio system comprising one or more user devices connected to a network having at least one audio amplifier and associated loudspeakers. The one or more user devices may comprise memory holding a plurality of libraries of audio items in digital form, each library being associated with a particular user. The one or more user devices may also comprise means for compiling a database of information relating to the audio items in each library. The database of each library may be available to any user, and selection of an item from a database causes the item to be played from the library in which the audio data is held. | 01-09-2014 |
Scott D. Dalgleish, Boulder, CO US
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20110213559 | MULTI-SENSOR PATCH AND SYSTEM - Embodiments of the invention provide systems and methods for remote sensing and/or monitoring utilizing a sensing device, such as may be implemented in a patch that can be placed on or affixed to a subject, where the sensing device includes multiple sensors. For example, one embodiment of the present invention includes a wireless human temperature skin patch providing accurate measurement of human temperature from a sensing device applied to the skin and even in the presence of differing ambient temperature. In such an embodiment, the patch can include, for example, a flexible, breathable bandage or adhesive strip or pad to affix the sensing device to a patient. The sensing device can include multiple sensors such as two or more temperature sensors that can be used to accurately determine the patient's core body temperature from the measured temperature at the skin. | 09-01-2011 |