Patent application number | Description | Published |
20080206440 | Bioabsorbable Polymeric Composition and Medical Device Background - A method for fabricating an embodiment of a medical device comprising the steps of: preparing a biodegradable polymeric structure; coating the biodegradable polymeric structure with a polymeric coat including a pharmacological or biological agent; cutting the structure into patterns configured to allow for crimping of the cut structure and expansion of the cut structure after crimping into a deployed configuration. | 08-28-2008 |
20090240317 | Bioabsorbable Polymeric Medical Device - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 09-24-2009 |
20090281249 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 11-12-2009 |
20090281617 | Sleeves for Positioning a Stent on a Delivery Balloon Catheter System - The present invention provides one or more sleeves for positioning a stent on a stent delivery system, such as a balloon catheter. The sleeve wraps around the catheter. One or two sleeves are positioned adjacent to one or both ends of the stent without overlapping with the stent. One end of the sleeve may be attached to the catheter or the balloon. The outer diameter of the end of the sleeve adjacent to the stent may be no greater than the outer diameter of the unexpanded stent. As a result, the profile of the stent delivery system is not increased by the sleeves of the present invention. If the stent dislodges during delivery to the target site, the stent can come to rest on the wall of the sleeve. Because the sleeves are positioned adjacent to the stent without overlapping with the stent, the stent is able to expand without being restrained by the sleeves. In addition, except for the stent, no other component of the stent delivery system, including the sleeves, comes into contact with the vessel wall when the balloon is expanded. This minimizes damages caused by the stent delivery system to the vessel. | 11-12-2009 |
20100003327 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 01-07-2010 |
20100093946 | Bioabsorbable Polymeric Compositions and Medical Devices - The bioabsorbable polymers and compositions of the present invention may be formed into medical devices such as stents that can be crimped onto a catheter system for delivery into a blood vessel. The properties of the bioabsorbable polymers allow for both crimping and expansion of the stent. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics. Typically, bioabsorbable polymers comprise aliphatic polyesters based on lactide backbone such as poly L-lactide, poly D-lactide, poly D,L-lactide, mesolactide, glycolides, lactones, as homopolymers or copolymers, as well as formed in copolymer moieties with co-monomers such as, trimethylene carbonate (TMC) or ε-caprolactone (ECL). | 04-15-2010 |
20100094405 | Bioabsorbable Polymeric Medical Device - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 04-15-2010 |
20110125251 | Self-Expanding Stent with Polygon Transition Zone - The self-expanding stent of the present invention provides for a transition zone between the main body of the stent and the end zone, comprising a plurality of n-sided polygons where the surface area of the adjacent polygons in the transition zone is unequal. In one embodiment, the surface area of the polygons in the transition zone increases circumferentially across the transition zone in a clockwise or counterclockwise manner. The polygons are formed from two pairs of undulations which are connected by segments. The bending moment of the undulations is equal within each polygon and constant across the transition zone. | 05-26-2011 |
20110130521 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 06-02-2011 |
20110130822 | Bioabsorbable Polymeric Compositions and Medical Devices - The present invention comprises a stent forming a plurality of meandering elements comprising a blend formed from a polymer. The polymer comprises poly-L-lactide, poly-D-lactide or mixtures thereof and a copolymer moiety comprising poly-L-lactide or poly-D-lactide linked with ε-caprolactone or trimethylcarbonate. The poly-L-lactide or poly-D-lactide sequence in the copolymer moiety is random with respect to the distribution of ε-caprolactone or trimethylcarbonate and the copolymer moiety molecular weight ranges from about 1.2 IV to about 4.8 IV. The meandering elements may be stretched to a modulus ranging from about 250000 PSI to about 550,000 PSI, one segment of the meandering element has a decreased cross-sectional area and may have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35. In various embodiment, two, three or n segments of the meandering element have a decreased cross-sectional area and may also have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35 after stretching. In another embodiment, all segments of the meandering element have a decreased cross-sectional area and may also have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35 after stretching. The meandering element may comprise a helical winding, a circumferential winding or stent ringlet. The properties of the bioabsorbable polymers allow for both crimping and expansion of the stent. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics. | 06-02-2011 |
20110208294 | BIOABSORBABLE MEDICAL DEVICE WITH COATING - A biodegradable, bioabsorbable medical device with a coating for capturing progenitor endothelial cells in vivo and delivering a therapeutic agent at the site of implantation. The coating on the medical device is provided with a biabsorbable polymer composition such as a bioabsorbable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive for controlling the rate of delivery of the therapeutic agent. | 08-25-2011 |
20120142869 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 06-07-2012 |
20130123906 | BIOABSORBABLE POLYMERIC MEDICAL DEVICE - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 05-16-2013 |
20130131782 | BIOABSORBABLE POLYMERIC MEDICAL DEVICE - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 05-23-2013 |
20130245206 | Bioabsorbable Polymeric Compositions and Medical Devices - The bioabsorbable polymers and compositions of the present invention may be formed into medical devices such as stents that can be crimped onto a catheter system for delivery into a blood vessel. The properties of the bioabsorbable polymers allow for both crimping and expansion of the stent. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics. Typically, bioabsorbable polymers comprise aliphatic polyesters based on lactide backbone such as poly L-lactide, poly D-lactide, poly D,L-lactide, mesolactide, glycolides, lactones, as homopolymers or copolymers, as well as formed in copolymer moieties with co-monomers such as, trimethylene carbonate (TMC) or ε-caprolactone (ECL). | 09-19-2013 |
20130268054 | Bioabsorbable Polymeric Medical Device - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 10-10-2013 |
20130268055 | MEDICAL DEVICE FOR IMPLANTATION INTO LUMINAL STRUCTURES - Stents may comprise a bioabsorbable polymer and a plurality of circumferential elements. Circumferential elements that are adjacent to one another may form an adjacent pair that is connected by one or more first connection elements and one or more second connection elements. In some embodiments, the circumferential elements may be formed from undulations having a sinusoidal pattern. The first and second connection elements and portions of the circumferential elements may form a substantially helical pattern across the longitudinal axis of the stent. In one embodiment, the first connection element may include one or more radiopaque markers. In some embodiments, the second connection elements may be curvilinear and may become substantially linear after the expansion of the stent. Curvilinear second connection elements may facilitate the expansion of the stent radially while overall length of the stent remains substantially constant. | 10-10-2013 |
20130289220 | Bioabsorbable Polymeric Compositions and Medical Devices - The present invention comprises a stent comprising a blend formed from a polymer. The polymer comprises poly-L-lactide, poly-D-lactide or mixtures thereof and a copolymer moiety comprising poly-L-lactide or poly-D-lactide linked with ε-caprolactone or trimethylcarbonate. The poly-L-lactide or poly-D-lactide sequence in the copolymer moiety is random with respect to the distribution of ε-caprolactone or trimethylcarbonate and the copolymer moiety molecular weight ranges from about 1.2 IV to about 4.8 IV. The meandering elements may be stretched to a modulus ranging from about 250000 PSI to about 550,000 PSI. One, two, three, n or all segments of the meandering element may have a decreased cross-sectional area and may have a wide-angle X-ray scattering (WAXS) 2θ values of ranging from about 1 to about 35 after stretching. The crystal properties of the bioabsorbable polymers may change during crimping and/or expansion allowing for improved mechanical properties such as tensile strength and slower degradation kinetics. | 10-31-2013 |
20130345790 | MEDICAL DEVICE FOR IMPLANTATION INTO LUMINAL STRUCTURES - The present invention relates to expandable stents with a geometric design that exhibits a high degree of flexibility and significant radial strength. The stents of the present invention comprise a generally cylindrically shaped main body having a plurality of expandable first and second circumferential elements. When the stent is expanded, the second circumferential element forms a ring- or hoop-like structure. In certain embodiments, the main body contains a plurality of expandable first, second and third circumferential elements where both the second and third circumferential elements form a ring- or hoop-like structure when expanded. The stent may further comprise an end zone that caps the main body, or two end zones positioned at both ends of the main body. | 12-26-2013 |
20140114434 | MEDICAL DEVICE FOR IMPLANTATION INTO LUMINAL STRUCTURES - The present invention relates to expandable scaffolds such as stents. The vascular scaffolds may be formed from bioabsorbable polymers, metals or various combinations of metals and polymers. The stents of the present invention comprise a generally cylindrically shaped main body having a plurality of expandable first and second circumferential elements. The body of the vascular scaffold comprises a plurality of circumferential elements. At least two circumferential elements may be connected to form a pair of circumferential elements. There may be one or more connections between the circumferential elements forming the pair. Each pair of circumferential elements is connected to an adjacent pair of circumferential elements by at least one connection element. When expanded, at least a portion of the connection elements connecting the circumferential elements in the pairs and/or the connection elements connecting the circumferential elements in adjacent pairs form a contiguous spiral pattern which may form a helix(s). | 04-24-2014 |
20140135901 | BIOABSORBABLE MEDICAL DEVICE WITH COATING - A biodegradable, bioabsorbable medical device with a coating for capturing progenitor endothelial cells in vivo and delivering a therapeutic agent at the site of implantation. The coating on the medical device is provided with a biabsorbable polymer composition such as a bioabsorbable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive for controlling the rate of delivery of the therapeutic agent. | 05-15-2014 |
20140336748 | BIOABSORBABLE POLYMERIC MEDICAL DEVICE - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 11-13-2014 |
20150028513 | BIOABSORBABLE POLYMERIC COMPOSITION AND MEDICAL DEVICE - A method for fabricating an embodiment of a medical device comprising the steps of: preparing a biodegradable polymeric structure; coating the biodegradable polymeric structure with a polymeric coat including a pharmacological or biological agent; cutting the structure into patterns configured to allow for crimping of the cut structure and expansion of the cut structure after crimping into a deployed configuration. | 01-29-2015 |
20150032200 | BIOABSORBABLE POLYMERIC MEDICAL DEVICE - In embodiments there is described a cardiovascular tube-shaped lockable and expandable bioabsorbable scaffold having a low immunogenicity manufactured from a crystallizable bioabsorbable polymer composition or blend. | 01-29-2015 |
20150073099 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 03-12-2015 |
20150073100 | Bioabsorbable Polymeric Composition for a Medical Device - A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer additive. Medical devices manufactured from the composition are also provided. | 03-12-2015 |
20150112422 | Medical Device for Implantation into Luminal Structures Incorporating Corrugated Structural Elements - Expandable scaffolds or stents include circumferential elements having a corrugated pattern, which can include a plurality of linear or nonlinear segments. The corrugated pattern distributes stress more uniformly along the circumferential elements, improves radial strength of the scaffolds, reduces acute recoil after deployment, and reduces creep. The scaffolds can be made from a bioabsorbable material. | 04-23-2015 |