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Corine

Corine Bertolotto-Ballotti, Nice FR

Patent application numberDescriptionPublished
20150056195COMPOSITIONS AND METHODS FOR INIHIBITING TUMORIGENICITY OF SENESCENT CANCER CELLS INDUCED BY CHEMOTHERAPY - The invention relates to the field of oncology and to chemotherapy resistance and relapse. Thus the invention provides compositions and methods for inhibiting tumorigenicity of senescent cancer cells induced by a chemotherapeutic agent. The invention also provides compositions and methods for inhibiting conversion of non-stem cancer cells (non-CSCs) into tumor initiating cancer stem cells (CSCs) induced by a chemotherapeutic agent.02-26-2015

Corine Bertolotto-Ballotti, Nice Cedex 3 FR

Patent application numberDescriptionPublished
20140199292COMPOSITIONS AND METHODS FOR INHIBITING TUMOR DEVELOPMENT CAUSED BY CHEMOTHERAPY INDUCED SENESCENCE - The present invention relates to products and compositions containing (i) a chemotherapeutic agent and (ii) at least an active compound chosen from CCL2 inhibitors, CCR2 inhibitors, NF-κB inhibitors, PARP-1 inhibitors and ATM inhibitors, as a combined preparation for simultaneous, separate or sequential use for inhibiting tumor development caused by tumor cell senescence induced by said chemotherapeutic agent. The invention also refers to a method for monitoring the response to a chemotherapeutic agent of a patient suffering from a cancer, and to a method for predicting the tumor size evolution and/or the onset of metastasis in a patient suffering from a cancer.07-17-2014

Corine Cochennec, Voiron FR

Patent application numberDescriptionPublished
20140220214Method for preparing an aromatic composition including a compound containing two solids having organoleptic properties - A method for preparing an aromatic pulverulent composition having a melting point Tf, comprising: i) feeding at least two pulverulent elementary solids having organoleptic properties into a mixer, whose chamber has been preheated beforehand to a temperature T lower than Tf, such solids being separately fed into the mixer; ii) mixing the pulverulent elementary solids in the mixer, in the absence of any external liquid phase, at a temperature T lower than Tf, at least one of the pulverulent elementary solids being fed into the mixer at a temperature Ti, such that the mixing occurs under isothermal conditions at a temperature set at such temperature T; and iii) recovering the aromatic pulverulent composition. This method is particularly suitable for preparing a composition essentially including a vanillin and ethylvanillin compound.08-07-2014
20140316165Method for purifying vanillin by liquid-liquid extraction - A method is described for purifying vanillin, and derivatives thereof, from an initial solution of vanillin or of a vanillin derivative in a solvent S1 containing impurities, comprising the following steps: a) a step of evaporating the solvent S1 in the presence of water from such initial solution to obtain an aqueous solution of vanillin or of a vanillin derivative; b) a step of liquid/liquid extraction by bringing the aqueous solution obtained at the end of step a) into contact with a solvent S2, at a pH of greater than 8 and less than 10, to obtain an organic phase and an aqueous phase containing vanillin or a vanillin derivative and residual solvent S2; c) a step of precipitating, at a pH between 4 and 7.5, the vanillin contained in the aqueous phase obtained at the end of step b); and d) a step of isolating the vanillin or derivative thereof.10-23-2014
20140323769Method for preparing a vanillin derivative - A method for preparing a compound of formula (I) which is a vanillin derivative, of dimer type, called 3-(4-hydroxy-3-methoxybenzyl)-4-hydroxy-5-methoxybenzaldehyde, such method comprising a reaction of vanillin and vanillyl alcohol in the presence of a base.10-30-2014
20150044348New use for a compound of vanillin and ethyl vanillin in a food product - The present invention concerns a new use for a compound of vanillin and ethyl vanillin, in a food product and more particularly in a food product with a reduced fat and/or sugar content. The present invention also concerns food compositions comprising said compound of vanillin and ethyl vanillin.02-12-2015

Corine Fulchiron, Serrieres De Briord FR

Patent application numberDescriptionPublished
20140161330BIO-IMAGING METHOD AND SYSTEM - A method for enhancing an image of a biological sample, which biological sample has been grown in a vessel on a culture medium.06-12-2014
20140293036BIO-IMAGING METHOD AND SYSTEM - An imaging system for generating images of biological samples having a surface, the system comprising: a sample support for supporting a biological sample in use; a plurality of illumination sources, the plurality of illumination sources being arranged around the sample support and each adapted to illuminate the biological sample, in use, from a different direction; an image capture device for capturing illumination which has impinged on the biological sample to thereby form an image of the sample; wherein at least one of the illumination sources direction is not perpendicular to the surface of the sample.10-02-2014

Corine Gessier-Vial, Altkirch FR

Patent application numberDescriptionPublished
20120126440Manufacture Process - The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.05-24-2012

Corine In-Gerardin, Grabels FR

Patent application numberDescriptionPublished
20110028576MESOPOROUS MATERIALS AND REACTANTS FOR PREPARING THEM - The invention relates to a process for manufacturing porous materials, which comprises the following steps: preparation of a solution of at least one structuring agent, having at least two structuring parts linked by at least one type of reversible non-covalent interaction; formation of the structured or porous material; separation of the at least two parts of the structuring agent at low temperature; and recovery of at least 50% by weight of the two non-degraded structuring parts and the porous material.02-03-2011

Corine Kolenda, Carol Stream, IL US

Patent application numberDescriptionPublished
20120222581CONSTANT CONTACT SIDE BEARING - A constant contact side bearing (CCSB) for use between a truck and car of a rail car that includes a generally hollow housing that includes a closed bottom end and an open top end. An attachment member is attached to an outside surface of the housing and is positioned in a center region between the top end and the bottom end. A resilient member is positioned inside the housing, and a cap is fitted over resilient member and is sized relative to the housing to enable slidibly moving into the housing.09-06-2012

Corine Sermeus, Silly BE

Patent application numberDescriptionPublished
20140105823MOLECULES SPECIFICALLY BINDING PANCREATIC BETA CELLS BIOMARKERS - The present invention provides a synthetic peptide molecule that specifically binds an FXYD2-gamma isoform of pancreatic beta cells, said synthetic peptide molecule has 25 amino acids.04-17-2014

Corine Vialas, Irigny FR

Patent application numberDescriptionPublished
20110150837Amphiphilic polymer functionalized by methionine - The present invention relates to new amphiphilic polymers comprising hydrophobic groups and methionine groups.06-23-2011
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