Patent application number | Description | Published |
20100259735 | FLUID HANDLING DEVICE, AN IMMERSION LITHOGRAPHIC APPARATUS AND A DEVICE MANUFACTURING METHOD - A fluid handling system for an immersion lithographic apparatus that has a fluid removal device to remove immersion liquid from an immersion space, and a droplet removal device to remove a droplet of immersion liquid, wherein: the droplet removal device is located further from an optical axis than the fluid removal device, and the droplet removal device comprises a porous member which faces, e.g., the substrate being exposed and/or the substrate table. | 10-14-2010 |
20100290013 | Immersion Lithographic Apparatus and a Device Manufacturing Method - An immersion lithographic apparatus has a pressure sensor configured to measure the pressure of immersion liquid in a space between the substrate and a projection system. A control system is responsive to a pressure signal generated by the pressure sensor and controls a positioner to exert a force on the substrate table to compensate for the force exerted on the substrate table by the immersion liquid. | 11-18-2010 |
20120013865 | LITHOGRAPHIC APPARATUS AND METHOD - A substrate table to support a substrate on a substrate supporting area, the substrate table having a heat transfer fluid channel at least under the substrate supporting area, and a plurality of heaters and/or coolers to thermally control the heat transfer fluid in the channel at a location under the substrate supporting area. | 01-19-2012 |
20130045447 | LITHOGRAPHIC APPARATUS, SUPPORT TABLE FOR A LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A support table configured to support a substrate, the support table having a support section to support a substrate and a conditioning system to supply heat energy to and/or remove heat energy from the support section, wherein the conditioning system comprises a plurality of conditioning units that are independently controllable. | 02-21-2013 |
20130149649 | LITHOGRAPHIC APPARATUS AND A DEVICE MANUFACTURING METHOD - A lithographic apparatus having: a substrate table constructed to hold a substrate; a projection system configured to project a patterned radiation beam onto a target portion of the substrate; a substrate surface actuator including a fluid opening for fluid flow therethrough from/onto a facing surface facing the substrate surface actuator to generate a force between the substrate surface actuator and the facing surface, the facing surface being a top surface of the substrate or a surface substantially co-planar with the substrate; and a position controller to control the position and/or orientation of a part of the facing surface by varying fluid flow through the fluid opening to displace the part of the facing surface relative to the projection system. | 06-13-2013 |
Patent application number | Description | Published |
20120149737 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, are (selective) retinoic acid receptor α (RARα) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RARα, and in the treatment of diseases and conditions that are mediated by RARα, that are ameliorated by the activation of RARα, etc., including cognitive disorders, memory impairment, memory deficit, senile dementia, Alzheimer's disease, early stage Alzheimer's disease, intermediate stage Alzheimer's disease, late stage Alzheimer's disease, cognitive impairment, and mild cognitive impairment. | 06-14-2012 |
20160039747 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use - The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain aryl-amido-aryl compounds of the following formula (for convenience, collectively referred to herein as “AAA compounds”), which, inter alia, are (selective) retinoic acid receptor α (RARα) agonists. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to (selectively) activate RARα, and in the treatment of diseases and conditions that are mediated by RARα, that are ameliorated by the activation of RARα, etc., including cognitive disorders, memory impairment, memory deficit, senile dementia, Alzheimer's disease, early stage Alzheimer's disease, intermediate stage Alzheimer's disease, late stage Alzheimer's disease, cognitive impairment, and mild cognitive impairment. | 02-11-2016 |
Patent application number | Description | Published |
20090318861 | METHOD OF THERMAL TREATMENT OF A THERMALLY RESPONSIVE MATERIAL OF MEDICAL DEVICES - The present invention relates to a method of thermal treatment of thermally responsive material wherein areas in or on the material to be thermally treated are defined and thermal energy is inputted on or into the defined areas in order to change/influence the material characteristics. The present invention further relates to medical devices or parts thereof manufactured at least in part from thermally responsive material by a process comprising at least one step of thermal treatment of this thermally responsive material. | 12-24-2009 |
20110172696 | CATHETER HAVING A SOFT DISTAL TIP - The present invention relates to a catheter having a soft distal tip that can be manufactured at lower cost than catheters in the prior art. In one embodiment, the catheter is produced by coupling a soft sleeve to the distal end of a catheter tube. The sleeve may affixed to the catheter tube under temperature and pressure conditions that cause the proximal end of the sleeve to taper against the outer surface of the catheter tube, avoiding or minimizing discontinuities in the insertion profile of the catheter, and that also cause the inner wall of the sleeve to taper against the distal end of the catheter tube, avoiding or minimizing discontinuities in the lumen of the catheter. | 07-14-2011 |
20120203172 | CATHETER HAVING A SOFT DISTAL TIP - The present invention relates to a catheter for POBA or stent delivery applications. More specifically, the present invention relates to a balloon catheter having a soft distal tip member and methods for manufacturing the same. | 08-09-2012 |
20150126971 | SHAFT FOR MEDICAL DEVICES AND CATHETER - The application relates to a shaft ( | 05-07-2015 |
20150174365 | METHOD OF THERMAL TREATMENT OF A THERMALLY RESPONSIVE MATERIAL OF MEDICAL DEVICES - The present invention relates to a method of thermal treatment of thermally responsive material wherein areas in or on the material to be thermally treated are defined and thermal energy is inputted on or into the defined areas in order to change/influence the material characteristics. The present invention further relates to medical devices or parts thereof manufactured at least in part from thermally responsive material by a process comprising at least one step of thermal treatment of this thermally responsive material. | 06-25-2015 |
Patent application number | Description | Published |
20100092477 | METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER - A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased. Specifically disclosed is an AR IgG1 Fc fusion protein, comprising the androgen binding domain of human androgen receptor and the Fc region of IgG. This fusion protein is used in the treatment of prostate cancer and testosterone flare. | 04-15-2010 |
20100291086 | USE OF ESTROGEN AND ANDROGEN BINDING PROTEINS IN METHODS AND COMPOSITIONS FOR TREATING GYNAECOLOGICAL CANCERS - The present invention provides a polypeptide comprising an estrogen or androgen binding region, the binding region capable of binding to an estrogen or androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available estrogen or androgen is decreased. The invention also provides for the treatment or prevention of cancers such as ovarian cancer, breast cancer and endometrial cancer using the polypeptides. | 11-18-2010 |
20130064821 | METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER - A polypeptide comprising an androgen binding region, the androgen binding region capable of binding to an androgen at a sufficient affinity or avidity such that upon administration of the polypeptide to a mammalian subject the level of biologically available androgen is decreased. Specifically disclosed is an AR IgG1 Fc fusion protein, comprising the androgen binding domain of human androgen receptor and the Fc region of IgG. This fusion protein is used in the treatment of prostate cancer and testosterone flare. | 03-14-2013 |
20140141104 | TREATMENT OF NEURODEGENERATIVE DISEASES - Use of selenate or a pharmaceutically acceptable salt thereof in methods and compositions for enhancing the activity of the protein phosphatase PP2A is provided. Methods of reducing phosphorylation of tau protein, inhibiting activity of GSK3 and treating or preventing neurodegenerative diseases are also described. | 05-22-2014 |
Patent application number | Description | Published |
20110283825 | Linkage - A linkage includes two gearboxes each having a driven shaft, and at least one linear actuator connected between the gearboxes. Actuation of the at least one linear actuator adjusts the relative position of the driven shafts for the two gearboxes with respect to each other. | 11-24-2011 |
20110284338 | Arrestor - A system having a rotary output, including a drive shaft, a pin coupled to the drive shaft and an output shaft coupled to the drive shaft. A guideway is associated with the output shaft. Rotation of the drive shaft results in rotation of the output shaft and the guideway and movement of the pin along a pin path. The system is prevented from providing a rotary output when the pin abuts against a sidewall of the guideway, but permitted to provide a rotary output when the portion of the guideway aligned with the pin path corresponds with the position of the pin. | 11-24-2011 |
20110290057 | Gearbox - A gearbox having a housing, an actuator, a leadscrew rotated by the actuator, a rack nut threadingly engaged with the leadscrew to move longitudinally as the leadscrew rotates, a toothed section that moved with the rack nut, a shaft and a gear integral with or coupled to the shaft, and arranged such that rotation of the gear causes rotation of the shaft. | 12-01-2011 |
20130019703 | MULTI AXIS MANOEUVRABLE PLATFORM - A manoeuvrable platform comprising a planar base manoeuvrable by at least one cam operated lifting sub system positioned in relation to a back surface of the base, the or each lifting sub system comprising a cam blade arranged in a plane substantially parallel to that of the planar base section and operably connected to a cam drive in a casing, a first linear actuator operably connected to the cam drive casing and configured to provide linear displacement along a first axis, a second linear actuator operably connected to the cam drive casing and configured to provide linear displacement along a second axis and a pivoting means arranged for rotating the planar base. | 01-24-2013 |
20130020852 | LOAD RESPONSIVE SEAT/BED - A support section for a seat ( | 01-24-2013 |
20130113215 | FLUID ACTUATED ENERGY GENERATOR - A fluid actuated energy generator comprises; an output shaft ( | 05-09-2013 |
20130119734 | SELF LOCKING MODULAR ARTICULATED FRAME - An articulating frame comprising parallel aligned base frame elements ( | 05-16-2013 |