Patent application number | Description | Published |
20110053962 | AZAINDOLE DERIVATIVES WITH A COMBINATION OF PARTIAL NICOTINIC ACETYL-CHOLINE RECEPTOR AGONISM AND DOPAMINE REUPTAKE INHIBITION - Azaindole derivatives of formula (I): | 03-03-2011 |
20120095039 | HETEROCYCLIC COMPOUNDS WITH AFFINITY TO MUSCARINIC RECEPTORS - The present invention relates to heterocyclic compounds of formula (I) having affinity to muscarinic receptors, a pharmaceutical composition containing the compounds, as well as the use of the compounds for the preparation of a medicament for treating, alleviating or preventing muscarinic receptor mediated diseases and conditions. | 04-19-2012 |
20120220552 | (THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS - The present disclosure relates to (thio)morpholine derivatives of the formula (I) | 08-30-2012 |
20140080861 | HETEROCYCLIC COMPOUNDS IWTH AFFINITY TO MUSCARINIC RECEPTORS - The present invention relates to heterocyclic compounds of formula (I) having affinity to mascarinic receptors, a pharmaceutical composition containing the compounds, as well as the use of the compounds for the preparation of a medicament for treating, alleviating or prevention muscarinic receptor medicated diseases and conditions. | 03-20-2014 |
20150239857 | (THIO)MORPHOLINE DERIVATIVES AS S1P MODULATORS - The present invention relates to (thio)morpholine derivatives of the formula (I), wherein R1 is selected from cyano, (2-4C)alkynyl, (1-4C)alkyl, (3-6C)cycloalkyl, (4-6C)cycloalkenyl, (6-8C)bicycloalkyl, (8-10C)bicyclic group, each optionally substituted with (1-4C)alkyl, phenyl, biphenyl, naphthyl, each optionally substituted with one or more substituents independently selected from halogen, (1-4C)alkyl optionally substituted with one or more fluoro atoms, (2-4C)alkynyl, (1-4C)alkoxy optionally substituted with one or more fluoro atoms, amino, di(1-4C)alkylamino, —SO | 08-27-2015 |
Patent application number | Description | Published |
20130196998 | SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS - The present invention relates to spiro-cyclic amine derivatives of the formula (I) | 08-01-2013 |
20130203737 | FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS - The present invention relates to a fused heterocyclic derivative of the formula (I) | 08-08-2013 |
20140066433 | FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS - The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified sub-structures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia. | 03-06-2014 |
20150284403 | FUSED HETEROCYCLIC DERIVATIVES AS S1P MODULATORS - The present invention relates to a fused heterocyclic derivative of the formula (I) The variables R1-R4, z, A, Q, X and Y are as defined in the claims. The following heterocycles are exemplified sub-structures of formula (I): The compounds of formula (I) are modulators of the S1P receptor (Sphingosine-1-phosphate receptor), More specifically, they are agonists of S1P5. The compounds have therapeutic use in treatment of cognitive disorders, age-relate cognitive decline and dementia. | 10-08-2015 |
Patent application number | Description | Published |
20100018710 | FRACTURING FLUID COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF USE - The invention describes improved fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 01-28-2010 |
20100044048 | Non-toxic, green fracturing fluid compositions, methods of preparation and methods of use - The invention describes improved environmentally friendly, non-toxic, green fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of water-based mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 02-25-2010 |
20100044049 | GREEN COAL BED METHANE FRACTURING FLUID COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF USE - The invention describes improved environmentally friendly, non-toxic, CBM friendly, green fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of water-based mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 02-25-2010 |
20100101796 | Hydrocarbon-based fracturing fluid compositions, methods of preparation and methods of use - The invention describes improved fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 04-29-2010 |
20120247776 | Hydrocarbon-Based Fracturing Fluid Compositions, Methods Of Preparation And Methods Of Use - The invention describes improved fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 10-04-2012 |
20130157904 | GREEN COAL BED METHANE FRACTURING FLUID COMPOSITIONS, METHODS OF PREPARATION AND METHODS OF USE - The invention describes improved environmentally friendly, non-toxic, CBM friendly, green fracturing compositions, methods of preparing fracturing compositions and methods of use. Importantly, the subject invention overcomes problems in the use of water-based mists as an effective fracturing composition particularly having regard to the ability of a mist to transport an effective volume of proppant into a formation. As a result, the subject technologies provide an effective economic solution to using high ratio gas fracturing compositions that can be produced in a continuous (i.e. non-batch) process without the attendant capital and operating costs of current pure gas fracturing equipment. | 06-20-2013 |