Claus Ehrhardt
Claus Ehrhardt, Basel CH
Patent application number | Description | Published |
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20110014186 | ARYLSULFONAMIDE-BASED MATRIX METALLOPROTEASE INHIBITORS - The present invention provides a compound of formula (I): | 01-20-2011 |
20110263560 | Organic Compounds - 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification. | 10-27-2011 |
20130028843 | KALLIKREIN 7 MODULATORS - The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7. | 01-31-2013 |
Claus Ehrhardt, Loerrach DE
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20100240638 | Organic Compounds and their uses - The present application describes macrocyclic compounds of formula (I) with NS3 protease inhibitory activity for treating hepatitis C virus infection. | 09-23-2010 |
Claus Ehrhardt, Lorrach DE
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20080269255 | 4-Phenylpiperidine Derivatives as Renin Inhibitors - Compounds of the present invention having the formula (I) exhibit inhibitory activity on the natural enzyme renin. Thus, compounds of formula (I) may be employed for the treatment of hypertension, atherosclerosis, unstable coronary syndrome, congestive heart failure, cardiac hypertrophy, cardiac fibrosis, cardiomyopathy postinfarction, unstable coronary syndrome, diastolic dysfunction, chronic kidney disease, hepatic fibrosis, complications resulting from diabetes, such as nephropathy, vasculopathy and neuropathy, diseases of the coronary vessels, restenosis following angioplasty, raised intra-ocular pressure, glaucoma, abnormal vascular growth, hyperaldosteronism, cognitive impairment, alzheimers, dementia, anxiety states and cognitive disorders. | 10-30-2008 |
20090312304 | ORGANIC COMPOUNDS - 3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4-substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula I, | 12-17-2009 |
20100204159 | ORGANIC COMPOUNDS AND THEIR USES - The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases. | 08-12-2010 |
20100240679 | 4-Phenylpiperidine Derivatives as Renin Inhibitors - Compounds of the present invention having the formula | 09-23-2010 |
20120258954 | ArylSulfonamide Based Matrix Metalloprotease Inhibitors - The present invention provides a compound of formula (I): | 10-11-2012 |
20130096105 | ArylSulfonamide Based Matrix Metalloprotease Inhibitors - The present invention provides a compound of formula (I): | 04-18-2013 |
20150045398 | ArylSulfonamide-Based Matrix Metalloprotease Inhibitors - The present invention provides a compound of formula (I): | 02-12-2015 |
Claus Ehrhardt, Lorrach CH
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20100087427 | PYRROLIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE DEPENDING ON THE ACTIVITY OF RENIN - Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I | 04-08-2010 |
Claus Ehrhardt, Hamburg DE
Patent application number | Description | Published |
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20090152139 | PACKAGING SACHET AND METHOD AND DEVICE FOR PRODUCING THE SAME | 06-18-2009 |