Patent application number | Description | Published |
20100031735 | SYSTEM AND METHOD FOR ULTRASONIC MEASURING OF PARTICLE PROPERTIES - Devices, systems and methods for measuring and detecting properties of a variety of particles or cells in suspension. Properties, such as, for example, velocity of particles, concentration and/or size may be measured according to the methods of the invention. Acoustic energy may be introduced to a focal zone and narrow band interrogating signals may be used. The acoustic energy may cause movement or streaming of the fluid or suspension. The acoustic streaming may allow a Doppler effect measurement without any other source of velocity. | 02-11-2010 |
20100261277 | METHODS AND COMPOSITIONS FOR ENHANCED DIFFERENTIATION FROM EMBRYONIC STEM CELLS - The invention provides methods for differentiating pluripotent stem cells such as ES cells with improved progenitor and differentiated cell yield using low oxygen conditions and optionally in the absence of exogenously added differentiation factors. | 10-14-2010 |
20110045077 | ENCAPSULATED PANCREATIC ISLET CELL PRODUCTS AND METHODS OF USE THEREOF - This invention is directed, inter alia, to encapsulated cell products, compositions comprising the same and uses thereof to treat diabetes, and related complications, increase islet cell masses, improve a metabolic profile in a subject, and other related conditions. Processes to produce the encapsulated islet cell product are described. | 02-24-2011 |
20120203264 | Graft Systems Having Semi-Permeable Filling Structures and Methods for Their Use - Aneurysms are treated by filling at least one double-walled filling structure with a filling medium within the aneurysm, such as filling structures having a membrane that allows water molecules to permeate across the membrane in response to a water potential differential across the membrane. The transport of fluid across the membrane allows the bag to expand or shrink to accommodate changes in the size or shape of the aneurysm, thereby maintaining a seal between the filling structure against the vessel wall and maintaining apposition of the filling structure against the inside surface of the aneurysm. Transport of water molecules into or out of the filling structure is controlled by adjusting for the osmolarity of the filling fluid medium. The filling structures may be delivered over balloon deployment mechanisms in order to shape occlude the aneurysm and open a tubular lumen for flow of blood through the filling structure. | 08-09-2012 |
20120219532 | METHODS AND COMPOSITIONS FOR INCREASED SAFETY OF STEM CELL-DERIVED POPULATIONS - The invention provides methods and compositions relating to differentiated cell populations that derive from pluripotent stem cells. The methods relate to reducing the number of residual stem cells present in such populations. The compositions include differentiated cell populations that contain reduced number of stem cells or that contain no stem cells. Pluripotent stem cells may be reduced in number and/or function through exposure to low oxygen levels. | 08-30-2012 |
20130216480 | AMPHIPHILIC POLYMERS AND METHODS OF USE THEREOF - The present invention relates to amphiphilic polymers, and micelles and compositions comprising the same, and their use in a variety of biological settings, including imaging, targeting drugs, or a combination thereof for diagnostic and therapeutic purposes. | 08-22-2013 |
20130287743 | METHOD FOR DIFFERENTIATING HUMAN EMBRYONIC STEM CELLS INTO -CELLS FOR THE TREATMENT OF TYPE I DIABETES - The invention provides inter alia methods for differentiating embryonic stem cells into insulin producing cells, as well as compositions comprising such cells, and therapeutic uses of such compositions. | 10-31-2013 |
20140370598 | ARTICLES AND METHODS FOR STEM CELL DIFFERENTIATION - Articles and methods for stem cell differentiation are generally described. In some embodiments, an article for stem cell differentiation may comprise an oxygen permeable substrate having at least a portion of a surface coated with a matrix. The matrix may allow the surface chemistry of the substrate to be altered, such that the cell-substrate surface interactions may be finely controlled without substantially affecting the oxygen permeability of the substrate. The surface chemistry may be altered to promote directed stem cell differentiation by, e.g., modification of the matrix surface with a specific density of biological molecules. In some embodiments, methods for stem cell differentiation may comprise directing the differentiation of stem cells on the articles, described herein, under suitable environmental conditions. Articles and methods, described herein, may be free of xenogeneic components and particularly well-suited for applications involving the differentiation of human stem cells into specific lineages. | 12-18-2014 |