Patent application number | Description | Published |
20120041324 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. | 02-16-2012 |
20120150516 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining patient-specific cardiovascular information. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient and create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data. The at least one computer system may be further configured to determine a total resistance associated with a total flow through the portion of the anatomical structure of the patient, and determine information regarding a blood flow characteristic within the anatomical structure of the patient based on the three-dimensional model, a physics-based model relating to the anatomical structure of the patient, and the determined total resistance. | 06-14-2012 |
20120258488 | Systems and Methods for Electrophysiological Activated Cell Sorting and Cytometry - Provided herein are methods and systems for non-genetic, label-free cell purification (i.e., cell cytometry and sorting), which classifies cells based on their spontaneous electrophysiological response or their electrophysiological response to a stimulus. For example, in one embodiment, there is provided a method of cell sorting comprising: stimulating a cell with a stimulus; sensing a response evoked by the cell based on the stimulus; identifying a phenotype of the cell based on the evoked response; and sorting the cell based on its phenotype. In one embodiment, the stimulus may be an electrical stimulus, a mechanical stimulus, an optical stimulus, a thermal stimulus, a chemical stimulus, or any combination thereof. The cell phenotype may be, for example, cardiomyocytes, neurons, smooth muscle cells, or pancreatic beta cells. | 10-11-2012 |
20130064438 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. | 03-14-2013 |
20130066618 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. | 03-14-2013 |
20130151163 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. | 06-13-2013 |
20130196435 | STENCIL PATTERNING METHODS AND APPARATUS FOR GENERATING HIGHLY UNIFORM STEM CELL COLONIES - A method for producing highly uniform cell colonies in a cell culture dish with the use of stencils made from an elastomeric sheet sized to fit within the cell culture dish, having a singular opening or a plurality of openings of a number, pitch and diameter configured to optimally control the geometric growth parameters of a cell colony. The uniform cell colonies are produced by placing the stencil in a cell culture dish and hydropilizing the stencil. The stencil is overlayed with cell culture media and seeded with seed cells that are preferably grown for at least a day before the stencil is removed to produce a pattern of seeded cells with controlled pitch, colony diameter and density within the culture dish that grow to become highly uniform cell colonies. A kit with culture dish, stencil, culture media and growth media is also provided. | 08-01-2013 |
20130211728 | METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW - Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. | 08-15-2013 |