Chow, Los Altos
Andrea Chow, Los Altos, CA US
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20100112588 | METHODS FOR SANGER SEQUENCING USING PARTICLE ASSOCIATED CLONAL AMPLICONS AND HIGHLY PARALLEL ELECTROPHORETIC SIZE-BASED SEPARATION - Methods for highly parallel Sanger sequencing are discussed. In particular, provided herein are methods using particles to clonally amplify templates and to introduce the amplified nucleic acids into many parallel channels with a single template per channel. Once in the channels, the nucleic acids are separated by size using electrophoresis to produce long read length sequencing information. Methods involving optical detection of the size-separated nucleic acids and analysis of the resulting electropherograms to yield the sequences are disclosed. | 05-06-2010 |
20110059864 | Sequence Determination By Use Of Opposing Forces - The present teachings relate to systems, methods, and the like, for analyzing biological polymers, by use of opposing forces. Among other things, the present teachings can be used to determine sequence information, such as in genetic sequencing and genotyping applications. Various embodiments are described for efficient, high throughput sequencing of nucleic-acid molecules, such as DNA. Various embodiments are described wherein nucleic-acid sequence information is determined without the need or use of extrinsic labels. As well various embodiments of methods, systems, and the like, are described, which can provide long and accurate read lengths for low-cost nucleic acid sequencing. | 03-10-2011 |
20120220486 | METHODS AND APPARATUS FOR BINDING ASSAYS - The present teachings relate to methods, systems, and apparatus for low cost label-free assay detection. The present teachings, in a variety of embodiments, employ opposing forces to detect signals which depend on the number of charges on and/or the size of a particle. The particle, which can be subjected to opposing forces, can have specific capture probes at its surface. As analytes of interest are captured by the particle, the number of charges on the particle surface and/or the size of the particle is changed. A particle parameter or kinematic property such as the position, velocity, acceleration or force of/on the particle can be measured, and results obtained relating, for example, to the present, absence, quantity, and such, of one or more analytes of interest. Various embodiments are described for efficient, high throughput assays of samples potentially including one or more analytes of interest, such as bioanalytes. As well, various embodiments are described wherein binding assays can be carried out without the need or use of extrinsic labels. A number of embodiments provide, for example, methods, systems, and apparatus for detecting analytes (such as nucleic acids, proteins, cells and other entities, particulates, and the like) in one or more samples. Also described are: detection of a single copy of a target biomolecule, such as DNA, captured onto a trapped (e.g., tethered) bead; protocols for fabricating encoded bead arrays for multiplex assays; and methods, systems and apparatus for efficient and specific capture of pathogen biomolecular markers onto bead-bound capture probes, as well as detection and measurement of such capture events. | 08-30-2012 |
Andrea W. Chow, Los Altos, CA US
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20090137413 | Manipulation of Microparticles In Microfluidic Systems - Arrays of flowable or fixed particle sets are used in microfluidic systems for performing assays and modifying hydrodynamic flow. Also provided are assays utilizing flowable or fixed particle sets within a microfluidic system, as well as kits, apparatus and integrated systems comprising arrays and array members. | 05-28-2009 |
20100129896 | SYSTEM FOR DIFFERENTIATING THE LENGTHS OF NUCLEIC ACIDS OF INTEREST IN A SAMPLE - Systems for differentiating the lengths of nucleic acids of interest in a sample are provided. The system includes a microfluidic device, a detector, and a software system. The microfluidic device includes an amplification microchannel or microchamber containing a reaction mixture under conditions that provide one or more amplicons of the nucleic acid of interest. The detector is integral with or proximal to the microfluidic device and is configured to detect the amplicons as one or more signals from a homogenous mixture. The software system interprets one or more coincidentally detected signals to indicate lengths of one or more individual nucleic acid molecules of interest, thereby differentiating the lengths of the nucleic acids of interest. | 05-27-2010 |
20110063943 | CHANNEL CROSS-SECTION GEOMETRY TO MANIPULATE DISPERSION RATES - The present invention provides novel methods for controlling/manipulating materials flowing in a fluidic device. In particular, the methods of the invention create and utilize differences between dispersion rates and/or average velocity of materials in order to manipulate the materials. | 03-17-2011 |
20110118139 | Manipulation of Microparticles In Microfluidic Systems - An array of transportable particle sets is used in a microfluidic device for performing chemical reactions in the microfluidic device. The microfluidic device comprises a main channel and intersecting side channels, the main channel and side channels forming a plurality of intersections. The array of particle sets is disposed in the main channel, and the side channels are coupled to reagents. As the particle sets are transported through the intersections of the main channel and the side channels, reagents are flowed through the side channels into contact with each array member (or selected array members), thereby providing a plurality of chemical reactions in the microfluidic system. | 05-19-2011 |
20120273353 | HIGH THROUGHPUT MOBILITY SHIFT - The present invention provides novel methods for performing pulsed field mobility shift assays in microfluidic devices. In particular, the methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction. | 11-01-2012 |
Ching Tong Chow, Los Altos, CA US
Patent application number | Description | Published |
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20090208185 | MULTIPLE OUTPUT DIGITAL VIDEO RECORDING SYSTEM - A multimedia time warping system allows a user to store selected multimedia data streams while the user is simultaneously watching or reviewing other multimedia data. Data streams are converted to digital streams for internal transfer and manipulation. A parser and event buffer decouple the CPU from having to parse the digital stream. Video segments are stored on a storage device and when data is requested for display, its video segments are extracted from the storage device and sent to a decoder that converts them into display output signals and delivers the display output signals to a display. | 08-20-2009 |
20090269024 | MULTIMEDIA SIGNAL PROCESSING SYSTEM - A multimedia signal processing system utilizes an easily manipulated, low-cost storage and display system that allows the user to view a television program and instantly review previous scenes within the program. The invention also allows the user to store selected programs while simultaneously watching or reviewing another. A versatile system architecture enables providing the invention in multiple configurations, each adapted to receive input signals from a different source. At the highest level, the system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. Thus, several configurations are provided, each one requiring only minor system board modifications. The system architecture thus simplifies the design and manufacturing challenge presented by producing units to serve different markets, such as digital satellite, digital cable and analog cable. | 10-29-2009 |
20090269031 | MULTIMEDIA STREAM PROCESSING SYSTEM - A multimedia signal processing system allows a user to store selected programs while simultaneously watching or reviewing another. The system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. The system receives a digital stream and simultaneously processes the digital stream for display and stores the digital stream on at least one storage device. The system further simultaneously processes a previously recorded digital stream for display while processing the digital stream for display. | 10-29-2009 |
20100226627 | Multimedia Stream Processing System - A multimedia signal processing system allows a user to store selected programs while simultaneously watching or reviewing another. The system includes an input section and an output section. Across all configurations, the output section remains substantially the same, while the input section varies according to the signal type and the source. The system receives a digital stream and simultaneously processes the digital stream for display and stores the digital stream on at least one storage device. The system further simultaneously processes a previously recorded digital stream for display while processing the digital stream for display. | 09-09-2010 |
20140003791 | Multiple Outlet Digital Video Recording System | 01-02-2014 |
20140108585 | MULTIMEDIA CONTENT MANAGEMENT SYSTEM - A system allows a user to select multimedia content items from sources that include, but are not limited to, any of: Internet, network, or local. Selected multimedia content items may be stored in user specific caches residing in at least one cloud based storage device. Multimedia content items may be transcoded while or after being retrieved from a source and then stored in a user specific cache. Multimedia content items may be selected by a user from the user's specific cache and streamed to a user device. | 04-17-2014 |
Peter Chow, Los Altos, CA US
Patent application number | Description | Published |
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20140098705 | MANAGEMENT CENTER FOR COMMUNICATION SYSTEM CUSTOMER PREMISES EQUIPMENT - Described are systems and methods for a Digital Subscriber Line (DSL) customer premises equipment (CPE) Management Center (CMC). In one embodiment, the CMC includes a communications interface to receive information from the CPE device regarding operation of the CPE device. The received information is analyzed and a command signal generation module generates a corresponding command signal for transmission to the at least one CPE device to modify the CPE device operation based on the analysis results in a manner which either enhances CPE device performance, for example increasing data rate, or improves line stability, for example reducing CPE error rate. | 04-10-2014 |
20140321298 | SYSTEMS AND METHODS FOR JOINTLY OPTIMIZING WAN AND LAN NETWORK COMMUNICATIONS - Described are systems and methods for jointly optimizing Wide Area Network (WAN) and Local Area Network (LAN) network communications. In one embodiment, a management device communicatively interfaced with a WAN and a LAN includes a collection module to collect LAN information from the LAN and WAN information from the WAN; an analysis module to jointly analyze the collected WAN information and the collected LAN information to identify an operational condition; and an implementation module to initiate a management event responsive to the operational condition being identified. In one embodiment, the management event includes generating and transmitting a diagnostics report responsive to a fault being identified. The management device may further generate and execute instructions to remedy the diagnosed fault. | 10-30-2014 |
20140376370 | SYSTEMS AND METHODS FOR TRAFFIC AGGREGATION ON MULTIPLE WAN BACKHAULS AND MULTIPLE DISTINCT LAN NETWORKS - In accordance with embodiments disclosed herein, there are provided methods, systems, mechanisms, techniques, and apparatuses for traffic aggregation on multiple WAN backhauls and multiple distinct LAN networks; for traffic load balancing on multiple WAN backhauls and multiple distinct LAN networks; and for performing self-healing operations utilizing multiple WAN backhauls serving multiple distinct LAN networks. For example, in one embodiment, a first Local Area Network (LAN) access device is to establish a first LAN; a second LAN access device is to establish a second LAN; a first Wide Area Network (WAN) backhaul connection is to provide the first LAN access device with WAN connectivity; a second WAN backhaul connection is to provide the second LAN access device with WAN connectivity; and a traffic aggregation unit is to form a logically bonded WAN interface over the first WAN backhaul and the second WAN backhaul. In some embodiments an optional traffic de-aggregation unit may be used. | 12-25-2014 |
20150016260 | SYSTEMS AND METHODS FOR TRAFFIC LOAD BALANCING ON MULTIPLE WAN BACKHAULS AND MULTIPLE DISTINCT LAN NETWORKS - In accordance with embodiments disclosed herein, there are provided methods, systems, mechanisms, techniques, and apparatuses for traffic aggregation on multiple WAN backhauls and multiple distinct LAN networks; for traffic load balancing on multiple WAN backhauls and multiple distinct LAN networks; and for performing self-healing operations utilizing multiple WAN backhauls serving multiple distinct LAN networks. For example, in one embodiment, a first Local Area Network (LAN) access device is to establish a first LAN; a second LAN access device is to establish a second LAN; a first Wide Area Network (WAN) backhaul connection is to provide the first LAN access device with WAN connectivity; a second WAN backhaul connection to provide the second LAN access device with WAN connectivity; a management device is communicatively interfaced with each of the first LAN access device, the second LAN access device, the first WAN backhaul connection, and the second WAN backhaul connection; and the management device routes a first portion of traffic originating from the first LAN over the first WAN backhaul connection and routes a second portion of the traffic originating from the first LAN over the second WAN backhaul connection. | 01-15-2015 |