Cho, MA
George E.s. Cho, Hopkinton, MA US
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20100217248 | Methods And Systems For Laser Treatment Using Non-Uniform Output Beam - Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). | 08-26-2010 |
20110152847 | METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM - Methods and apparatus for treatment, such as skin rejuvenation treatment, using non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:YAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a non-uniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the target tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). A large area of tissue, preferably 7-10 mm in diameter, can be treated simultaneously, while minimizing the risk of burning or other damage to the skin. | 06-23-2011 |
20130035675 | NON-UNIFORM BEAM PHOTOTHERAPEUTIC DOSAGE DETERMINATION METHOD - This application provides a consumer device for aesthetic applications, and methods for titrating doses of therapeutic light output from the device in the form of a non-uniform beam, in connection with dermal rejuvenation and cosmetic applications. | 02-07-2013 |
20130096546 | NON-UNIFORM BEAM OPTICAL TREATMENT METHODS AND SYSTEMS - An apparatus is disclosed including: an incoherent light source that generates a treatment beam having a non-uniform energy profile, the non-uniform energy profile being included of regions of relatively high energy per unit area within a substantially uniform background region of relatively low energy per unit area. | 04-18-2013 |
20130178917 | METHODS AND SYSTEMS FOR LASER TREATMENT USING NON-UNIFORM OUTPUT BEAM - Disclosed herein are methods and systems for treatment, such as skin rejuvenation treatment, use non-uniform laser radiation. A high-intensity portion of the laser radiation causes collagen destruction and shrinkage within select portions of the treatment area, while a lower-intensity portion of the radiation causes fibroblast stimulation leading to collagen production across other portions of the treatment area. An output beam from a laser source, such as an Nd:NAG laser, is coupled into an optical system that modifies the beam to provide a large-diameter beam having a nonuniform energy profile, comprised of a plurality of high-intensity zones surrounded by lower-intensity zones within the treatment beam. The higher-intensity zones heat select portions of the tar et tissue to temperatures sufficient for a first treatment (e.g. collagen shrinkage), while the lower-intensity zones provide sufficient energy for a second treatment (e.g. stimulated collagen production). | 07-11-2013 |
Glen S. Cho, Brookline, MA US
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20100055761 | METHODS, COMPOSITIONS, AND KITS FOR THE SELECTIVE ACTIVATION OF PROTOXINS THROUGH COMBINATORAL TARGETING - The present invention provides methods and compositions for treating various diseases through selective killipg of targeted cells using a combinatorial targeting approach. The invention features protoxin fusion proteins containing a cell targeting moiety and, a modifiable activation moiety which is activated by an activation moiety not naturally operably found in, on, or in the vicinity of a target cell. These methods also include the combinatorial use of two or more therapeutic agents, at minimum comprising a protoxin and a protoxin activator, to target and destroy a specific cell population. | 03-04-2010 |
Glen S. Cho, Newton, MA US
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20140113832 | ENGINEERED THIOREDOXIN-LIKE FOLD PROTEINS - The invention features compositions based on thioredoxin-like fold protein domains described as engineered thioredoxin-like fold proteins (ETRXs). These proteins include one or more artificially diversified thioredoxin-like fold protein domains; each domain may be originated from the same or different thioredoxin-like fold protein domains. Features of the invention also include methods for identifying and preparing an enriched composition of target binding, loop-diversified ETRXs with additional sequence variations to improve affinity, stability, selectivity, or solubility. The invention also features compositions of ETRXs substituted with prosthetic groups, polymers, proteins, nucleic acids, carbohydrates, metals, natural or synthetic small molecules and toxins. | 04-24-2014 |
Hanchul Cho, Revere, MA US
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20140318967 | Damascene Template for Directed Assembly and Transfer of Nanoelements - Damascene templates have two-dimensionally patterned raised metal features disposed on an underlying conductive layer extending across a substrate. The templates are topographically flat overall, and the patterned conductive features establish micron-scale and nanometer-scale patterns for the assembly of nanoelements into nanoscale circuits and sensors. The templates are made using microfabrication techniques together with chemical mechanical polishing. These templates are compatible with various directed assembly techniques, including electrophoresis, and offer essentially 100% efficient assembly and transfer of nanoelements in a continuous operation cycle. The templates can be repeatedly used for transfer of patterned nanoelements thousands of times with minimal or no damage, and the transfer process involves no intermediate processes between cycles. The assembly and transfer processes employed are carried out at room temperature and pressure and are thus amenable to low cost, high-rate device production. | 10-30-2014 |
Hanwoo Cho, Acton, MA US
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20090235108 | AUTOMATIC PROCESSOR OVERCLOCKING - Processor overclocking techniques are disclosed. Upon automatically determining that overclocking entry criteria are satisfied, one or more cores are clocked above their standard operation frequencies. The cores may be overclocked until one or more exit criteria are satisfied. At that point, an exit procedure is performed, with the one or more overclocked cores return to their normal operating frequency. | 09-17-2009 |
20100073068 | FUNCTIONAL BLOCK LEVEL THERMAL CONTROL - An integrated circuit. The integrated circuit includes a plurality of functional units, wherein each of the plurality of functional units is implemented on a die of the integrated circuit. Each of the functional units includes one or more temperature sensors. The integrated circuit further includes a temperature control unit coupled to each of the functional units, wherein the temperature control unit is configured to monitor a temperature of each of the plurality of functional units based on temperature information provided from the temperature sensors. The temperature control unit is configured to, if the temperature exceeds a first threshold value for a particular one of the plurality of functional units, perform a first temperature control action on the particular one of the plurality of functional units independently of other ones of the plurality of functional units. | 03-25-2010 |
20120066445 | DYNAMIC RAM PHY INTERFACE WITH CONFIGURABLE POWER STATES - A physical memory interface (Phy) and method of operating is disclosed. The Phy interface includes command and status registers (CSRs) configured to receive a first power context and second power context. Selection circuitry is configured to switch between the first and second power contexts. A plurality of adjustable delay elements are provided, each having a delay time responsive to the selected power context. A first set of CSRs configured may store the first power context and a second set of CSRs configured may store the second power context. The Phy interface may also include a plurality of drivers each having a selectable drive strength responsive to the selected power context. The Phy interface may also include a plurality of receivers each having a selectable termination impedance responsive to the selected power context. Switching between power contexts may result in adjusting of the delay elements, drive strength and/or termination impedance of one or more drivers/receivers. | 03-15-2012 |
20120159271 | MEMORY DIAGNOSTICS SYSTEM AND METHOD WITH HARDWARE-BASED READ/WRITE PATTERNS - A memory loopback system and method including an address/command transmit source configured to transmit a command and associated address through an address/command path. A transmit data source is configured to transmit write data associated with the command through a write path. Test control logic is configured to generate gaps between successive commands. A loopback connection is configured to route the write data from the write path to a read path. A data comparator is configured to compare the data received via the read path to a receive data source and generate a data loopback status output. Pattern generation logic can be configured to generate a loopback strobe, the loopback strobe being coupled to the read path. The pattern generation logic may be configured to synthesize a read strobe based on the test control logic and to use the synthesized read strobe as the loopback strobe. The loopback connection may be configured to route the address/command data from the address/command path to an address/command comparator, the address/command comparator being configured to compare the address/command data to an address/command receive source and generate an address/command loopback status output. | 06-21-2012 |
20120290800 | METHOD AND APPARATUS TO REDUCE MEMORY READ LATENCY - A method and apparatus for training read latency of a memory are disclosed. A memory controller includes a command FIFO configured to convey commands to a memory, a data queue coupled to receive data from the memory, and a register configured to provide a value indicative of a number of cycles of a first clock signal after which data is valid. During a startup routine, the memory controller is configured to compare data received by the data queue to a known data pattern after a specified number of cycles of the first clock signal have elapsed. The memory controller is further to configured to decrement the first value and repeat conveying and comparing if the data received matches the data pattern. If the received data does not match the data pattern for any attempted read of the memory, the memory controller is configured to program a second value into the register. | 11-15-2012 |
20130124806 | DYNAMIC RAM PHY INTERFACE WITH CONFIGURABLE POWER STATES - A physical memory interface (Phy) and method of operating is disclosed. The Phy interface includes command and status registers (CSRs) configured to receive a first power context and second power context. Selection circuitry is configured to switch between the first and second power contexts. A plurality of adjustable delay elements are provided, each having a delay time responsive to the selected power context. A first set of CSRs configured may store the first power context and a second set of CSRs configured may store the second power context. The Phy interface may also include a plurality of drivers each having a selectable drive strength responsive to the selected power context. The Phy interface may also include a plurality of receivers each having a selectable termination impedance responsive to the selected power context. Switching between power contexts may result in adjusting of the delay elements, drive strength and/or termination impedance of one or more drivers/receivers. | 05-16-2013 |
Hanwoo C. Cho, Acton, MA US
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20100201343 | PROGRAMABLE DELAY MODULE TESTING DEVICE AND METHODS THEREOF - A data processing device is configured so that, in a test mode of operation, the phase of an output signal of a second programmable delay module (PDM) is based on the phase of the input signal of the first PDM. To test the first and second PDMs, the output signal of the first PDM is set to each of a first set of phases and the corresponding phase of the output signal of the second PDM is compared to determine whether the performance of the first and second PDMs match a specification. Accordingly, the first and second PDMs are qualified based on their relative performance, reducing the need for test structures that consume an undesirably large amount of area. | 08-12-2010 |
Hyungjoon Cho, Somerville, MA US
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20110105886 | DIFFUSION-BASED MAGNETIC RESONANCE METHODS FOR CHARACTERIZING BONE STRUCTURE - A method of in vitro or in vivo nuclear magnetic resonance and/or magnetic resonance imaging, to determine bone properties by measuring the effects of molecular diffusion inside the bone specimen to derive parameters that are related to the structure of the trabecular bones. The method is a non-invasive probe that provides topological information on trabecular bone without requiring a full high-resolution image of its structure, and is compatible with clinical use. | 05-05-2011 |
Hyun Jai Cho, Watertown, MA US
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20100119490 | Therapeutic Use of CD31 Expressing Cells - As described below, the present invention features compositions and methods related to the isolation, culture and therapeutic use of CD31-expressing cells. | 05-13-2010 |
Jae Hun Cho, Cambridge, MA US
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20150285765 | ACTIVE TRANSPORT OF CHARGED MOLECULES INTO, WITHIN, AND/OR FROM CHARGED MATRICES - Articles and methods for the active transport of molecules into, within, and/or from a matrix are generally described. In some embodiments, an electric field may be used to alter the position of the molecule with respect to the matrix. The electric field may be used to move the molecule to a new location within the matrix, remove the molecule from the matrix, or infuse the molecule into the matrix. For instance, the electric field may be used to move a molecule having a binding partner within the matrix into or away from the vicinity of the binding partner. In some embodiments, the position of the molecule may be altered by exposing the molecule to an electrodynamic field. In some such embodiments, the molecule exposed to the dynamic electric field may have enhanced mobility and minimal adverse matrix interactions relative to conventional molecular transport methods, and in some cases, a molecule exposed to an electrostatic field. The active transport methods and articles, described herein, may be particularly well-suited for a variety of applications including histological, biological, and pharmaceutical applications. | 10-08-2015 |
Jamie Cho, Stoughton, MA US
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20150142323 | METHOD AND SYSTEM FOR DETERMINING AN AMPLIFICATION QUALITY METRIC - According to one exemplary embodiment, a method for providing a amplification quality metric to a user is provided. The method includes receiving amplification data from an amplification of a sample to generate an amplification curve. The amplification curve includes an exponential region and a transition region. The method further includes determining a first value of the transition region and determining a second value of the transition region. The first value is the beginning of the transition region and the second value is the end of the transition region. Next, the amplification quality metric is calculated based on at least the first value and the second value. Then, the amplification quality metric is displayed to the user. | 05-21-2015 |
Jeffrey C. Cho, Northborough, MA US
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20120032816 | System And Method For Controlling Sport Event Transducers - A system and method for controlling a plurality of sport event transducers, each of which includes an output element that can emit a perceivable output in response to an event that relates to a sport team, such as for example by emitting an audio-visual output when a particular football team scores a touchdown. The system remotely controls such transducers in response to sport team events by broadcasting an RF signal carrying team event messages, such as for example by transmitting an FM radio-data broadcast that carries a team event message embedded in the FM signal as RDS data. The sport event transducer receives and decodes such RF broadcast signals. If the transducer receives a team event message that relates to the transducer's affiliated team, the transducer's output element emits an audio and/or visual output signal in response to the message. | 02-09-2012 |
20120034889 | Sport Event Transducer - A sport event transducer having an output element that can emit a perceivable output in response to an event that relates to a sport team, such as for example by emitting an audio-visual output when a particular football team scores a touchdown. The transducer can be removable attached to a sport garment such as a cap or jersey, or can be an integral part of the garment. A transmission system remotely controls such transducers in response to sport team events by broadcasting an RF signal carrying team event messages, such as for example by transmitting an FM radio-data broadcast that carries a team event message embedded in the FM signal as RDS data. The sport event transducer receives and decodes such RF broadcast signals. If the transducer receives a team event message that relates to the transducer's affiliated team, the transducer's output element emits an audio and/or visual output signal in response to the message. | 02-09-2012 |
20130106588 | Sport Event Transducer | 05-02-2013 |
Jeong Ju Cho, Lexington, MA US
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20140138591 | BLENDED CATHODE MATERIALS - A positive electroactive material is described, including: a lithium iron manganese phosphate compound having a composition of Li | 05-22-2014 |
20150064549 | ELECTROLYTE FORMULATION FOR REDUCED GASSING WIDE TEMPERATURE RANGE CYCLING - A rechargeable battery cell having a specific combination of anode, cathode and electrolyte formulation is provided. The electrolyte formulation includes an additive system and a salt system. The additive system includes a first additive containing a sulfonyl group, an anti-gassing agent, and a second additive. The salt system includes a lithium salt and a co-salt. The disclosed electrolyte formulation has reduced gassing and improved performance over a wide temperature range. | 03-05-2015 |
Jin Haeng Cho, Acton, MA US
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20140173208 | METHODS AND APPARATUS FOR MULTI-LEVEL CACHE HIERARCHIES - A multi-level cache structure in accordance with one embodiment includes a first cache structure and a second cache structure. The second cache structure is hierarchically above the first cache. The second cache includes a tag array comprising a plurality of tag entries corresponding to respective addresses of data within a system memory; a selector array associated with the tag array; and a data array configured to store a subset of the data. The selector array is configured to specify, for each corresponding tag entry, whether the data array includes the data corresponding to that tag entry. | 06-19-2014 |
Junghwan Cho, Dracut, MA US
May Cho, Sudbury, MA US
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20130306355 | Electrical Insulator Apparatus and Methods of Retaining an Electrical Conductor with an Electrical Insulator Apparatus - An electrical insulator apparatus and methods of using the same are provided. The apparatus includes an insulator body formed about a central axis, the insulator body having a plurality of spaced fins positioned along an exterior of the insulator body. A first jaw portion is positioned on an upper portion of the insulator body. A second jaw portion is positioned proximate to the first jaw portion and is movable with respect to the first jaw portion. At least one fastener is connected between the first and second jaw portions. A jaw platform is positioned at least partially between the first and second jaw portions, wherein the first and second jaw portions and the jaw platform form a notch sized to receive an electrical conductor, wherein the jaw platform substantially lies within a first plane angled substantially between 6° and 184° with respect to the central axis of the insulator body. | 11-21-2013 |
May K. Cho, Sudbury, MA US
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20080202794 | RATCHET-HEAD CONDUCTOR LOCKING MEDIUM VOLTAGE ELECTRICAL BUS POLYMER INSULATOR WITH PIN MOUNT - Cable support insulators of the present invention generally have an insulator body having a cable base and a plurality of insulator sheds. The cable base has a ratchet locking mechanism to secure an electrical conductor to the insulator. In preferred embodiments, a cable support insulator is provided that has an insulator body comprising a plurality of insulator sheds and a cable base. A locking base is connected to the cable base, and a retaining clamp is pivotally connected to the cable base. The cable base has a front end, a back end, and a seat adapted to receive a conductor cable. The locking base has a front plate having a plurality of ratchet teeth. The retaining clamp has a first retaining arm, a second retaining arm, and a locking blade. | 08-28-2008 |
20080203243 | RATCHET-HEAD CONDUCTOR LOCKING MEDIUM VOLTAGE POLYMER INSULATOR CABLE SUPPORT HANGER MOUNT - Cable support hanger insulators are provided herein that generally have a ratchet locking mechanism to secure an electrical conductor to the insulator. Cable support hanger insulators are provided that have an insulator body, a locking base connected to the insulator body, and a retaining clamp pivotally connected to the insulator body. The insulator body has a seat adapted to receive a conductor cable, a front end, a back end, a first side, and a second side. The locking base has a front plate having a plurality of ratchet teeth. The retaining clamp comprising a first retaining arm, a second retaining arm, and a locking blade. | 08-28-2008 |
Myong Hyon Cho, Cambridge, MA US
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20110258420 | EXECUTION MIGRATION - An execution migration approach includes bringing the computation to the locus of the data: when a memory instruction requests an address not cached by the current core, the execution context (current program counter, register values, etc.) moves to the core where the data is cached. | 10-20-2011 |
Patricia S. Cho, Cambridge, MA US
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20090220995 | MULTIPLE ADMINISTRATIONS OF UMBILICUS DERIVED CELLS - A method to determine the optimal administration protocol of allogeneic donor tissue to treat a disease in a human, using an animal model of human disease. | 09-03-2009 |
Richard William Cho, Newton Center, MA US
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20090123940 | MOLECULES INVOLVED IN SYNAPTOGENESIS AND USES THEREFOR - The present invention is based on the discovery that neuronal pentraxins play a role in the clustering and internalization of AMPA receptors, synaptogenesis, and metabotropic glutamate receptor-mediated long term depression (LTD) of a synapse. Accordingly, there are provided methods of identifying compounds that that modulate mGluR-mediated AMPA receptor internalization and LTD. Further provided are cleavage products of a member of the neuronal pentraxin family, neuronal pentraxin receptor (NPR). Also provided are isolated peptides comprising the Narp association regions 1 and 2 (NAR1 and NAR2, respectively) and the Narp binding motif (NBM) of AMPA receptors. Finally, there are provided antibodies that block binding of neuronal pentraxins to AMPA receptors, in particular, antibodies that bind NAR1, or NAR2, or NBM. | 05-14-2009 |
Sanghee Cho, Newton, MA US
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20100098312 | EXACT AND APPROXIMATE REBINNING OF TIME-OF-FLIGHT PET POSITRON EMISSION TOMOGRAPHY DATA - A technique for processing of data from time-of-flight (TOF) PET scanners. The size of TOF PET data may be reduced without significant loss of information through a process called rebinning. The rebinning may use the Fourier transform properties of the measured PET data, taken with respect to the time-of-flight variable, to perform data reduction. Through this rebinning process, TOF PET data may be converted to any of the following reduced representations: 2D TOF PET data, 3D non-TOF PET data, and 2D non-TOF PET data. Mappings may be exact or approximate. Approximate mappings may not require a Fourier transform in the axial direction which may have advantages when used with PET scanners of limited axial extent. Once TOF PET data is reduced in size using this rebinning, PET images may be reconstructed with hardware and/or software that is substantially less complex and that may run substantially faster in comparison to reconstruction from the original non-rebinned data. | 04-22-2010 |
Sungseo Cho, Sturbridge, MA US
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20090220895 | Metrology of bilayer photoresist processes - A method for patterning a substrate is provided, which comprises (a) providing a substrate; (b) applying a first layer comprising a first photo resist to the substrate; (c) applying a second layer comprising a second photo resist over the first layer; (d) patterning the second layer; and (e) inspecting the patterned second layer with an inspection tool; wherein at least one of the first and second layers comprises a contrasting agent which increases the contrast between the first and second layers to the inspection tool. | 09-03-2009 |
Taeg Sang Cho, Cambridge, MA US
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20090244300 | METHOD AND APPARATUS FOR MOTION INVARIANT IMAGING - Object motion during camera exposure often leads to noticeable blurring artifacts. Proper elimination of this blur is challenging because the blur kernel is unknown, varies over the image as a function of object velocity, and destroys high frequencies. In the case of motions along a 1D direction (e.g. horizontal), applicants show that these challenges can be addressed using a camera that moves during the exposure. Through the analysis of motion blur as space-time integration, applicants show that a parabolic integration (corresponding to constant sensor acceleration) leads to motion blur that is not only invariant to object velocity, but preserves image frequency content nearly optimally. That is, static objects are degraded relative to their image from a static camera, but all moving objects within a given range of motions reconstruct well. A single deconvolution kernel can be used to remove blur and create sharp images of scenes with objects moving at different speeds, without requiring any segmentation and without knowledge of the object speeds. | 10-01-2009 |
Woo Kyung Cho, Cambridge, MA US
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20130331792 | DEVICE AND USES THEREOF - The present disclosure provides devices and uses thereof. A devices disclosed herein comprises one or more tips, wherein the one or more tips are designed and constructed to initiate penetration by the device; and one or more protrusions in a region adjacent to each tip. In some embodiments, one or more protrusions can be constructed and arranged so that the required penetration force is reduced as compared with that observed for an otherwise identical device lacking the one or more protrusions. Additionally or alternatively, one or more protrusions can be constructed and arranged such that the required pull-out force is increased as compared with that observed for an otherwise identical device lacking the one or more protrusions. | 12-12-2013 |
Woo-Kyung Cho, Arlington, MA US
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20140148846 | Adhesive Articles Containing a Combination of Surface Micropatterning and Reactive Chemistry and Methods of Making and Using Thereof - Adhesive articles containing microtopography, such as microprotrusions, and a coating of adhesive glue, such an adhesive having known toxicity and/or tissue reactive functional groups are described herein. The articles described herein contain a substrate, a plurality of microfeatures, and an adhesive, such as an adhesive glue. The articles described herein exhibit a 90° pull off adhesion of at least about 1.5 N/cm | 05-29-2014 |
Yongku Peter Cho, Cambridge, MA US
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20140324134 | CHANNELRHODOPSINS FOR OPTICAL CONTROL OF CELLS - The invention, in some aspects relates to compositions and methods for altering cell activity and function and the introduction and use of light-activated ion channels. | 10-30-2014 |
Young Shin Cho, Cambridge, MA US
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20090247547 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B - The present teachings relate to compounds of Formula I: | 10-01-2009 |
20100022514 | Heterocycle Compounds and Methods of Use Thereof - The invention relates to the use of compounds in the treatment of deacetylase-associated diseases and for the manufacture of pharmaceutical preparations for the treatment of said diseases. | 01-28-2010 |
20100280033 | Pyrazole Derivatives - The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of diseases, particularly pyrazole compounds and derivatives are described which inhibit protein kinases. The organic compounds are useful in treating proliferative disease. | 11-04-2010 |
20110053925 | Hydroxamate-Based Inhibitors of Deacetylases - The present teachings relate to compounds of Formula I: | 03-03-2011 |
20110060009 | Hydroxamate-Based Inhibitors of Deacetylases - The present teachings relate to compounds of Formula I: | 03-10-2011 |
20110183964 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES B - The present teachings relate to compounds of Formula I: | 07-28-2011 |
20120101064 | IMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF CYCLIN DEPENDENT KINASES - The invention provides compounds of the formula (I): | 04-26-2012 |
20130150342 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 - The invention is directed to novel pyrrolopyrimidine compounds of formula (I) wherein R | 06-13-2013 |
20130231373 | HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES - The present teachings relate to compounds of Formula (I): and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, wherein R | 09-05-2013 |
20140235620 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH - The invention is directed to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R | 08-21-2014 |
20140275083 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH - The invention is directed to a formula (I): | 09-18-2014 |
20150099737 | PYRROLOPYRIMIDINE COMPOUNDS AS INHIBITORS OF CDK4/6 - The invention is directed to novel pyrrolopyrimidine compounds of formula (1) wherein R | 04-09-2015 |
20150152093 | 3-PYRIMIDIN-4-YL-OXAZOLIDIN-2-ONES AS INHIBITORS OF MUTANT IDH - The invention is directed to a formula (I): | 06-04-2015 |
Yun Hyung Cho, Lexington, MA US
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20130303618 | Solid Pharmaceutical Compositions Containing Pregabalin - A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone. | 11-14-2013 |
20140163103 | Solid Pharmaceutical Compositions Containing Pregabalin - A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone. | 06-12-2014 |
20150094371 | Solid Pharmaceutical Compositions Containing Pregabalin - A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone. | 04-02-2015 |
20150352066 | Solid Pharmaceutical Compositions Containing Pregabalin - A solid pharmaceutical composition containing pregabalin is described. The composition includes a matrix forming agent and a swelling agent and is suitable for once daily oral administration. Exemplary matrix forming agents include mixtures of polyvinyl acetate and polyvinylpyrrolidone, and exemplary swelling agents include cross-linked polymers of polyvinylpyrrolidone. | 12-10-2015 |