Chikauchi
Ken Chikauchi, Saitama-Ken JP
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20110003834 | PRODUCTION METHOD AND PRODUCTION APPARATUS FOR A HIGH THEOBROMINE-CONTAINING COMPOSITION - An object is to provide a method for producing a high theobromine-containing composition effectively in a simple way. The method for producing a theobromine-containing composition comprises: (a) performing an extraction of a theobromine-containing plant or a processed product thereof with a solvent, to obtain a crude theobromine extract; (b) applying the crude theobromine extract to a cation exchange resin subjected in advance to hydrogen ion substitution, to allow an adsorption of theobromine onto the cation exchange resin; and (c) passing a solvent containing no ionic substance through the cation exchange resin subsequently to the step (b), to obtain a theobromine eluate. | 01-06-2011 |
Ken Chikauchi, Chiba JP
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20090281292 | 10a-Azalide Compound - [Object]: To provide a compound having a novel structure effective against | 11-12-2009 |
Ken Chikauchi, Kanagawa JP
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20110237784 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS - A novel 10a-azalide compound crosslinked at the 10a- and 12-positions, which is represented by the following formula, and is effective on even | 09-29-2011 |
Ken Chikauchi, Kawasaki-Shi JP
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20120071457 | METALLO-BETA-LACTAMASE INHIBITORS - A new metallo-β-lactamase inhibitor which acts as a medicament for inhibiting the inactivation of β-lactam antibiotics and recovering anti-bacterial activities is disclosed. The maleic acid derivatives having the general formula (I) have metallo-β-lactamase inhibiting activities. It is possible to recover the anti-bacterial activities of β-lactam antibiotics against metallo-β-lactamase producing bacteria by combining the compound of the general formula (I) with β-lactam antibiotics. | 03-22-2012 |