Che

Chaw Che, Singapore SG

Patent application number	Description	Published
20140196251	SEMICONDUCTOR FABRICATING APPARATUS - A semiconductor fabricating apparatus includes a reaction chamber, a first gas pipeline, and a second gas pipeline. The first gas pipeline includes a first cleaning gas pipeline for providing a first cleansing gas to the reaction chamber in a cleansing process, and a second cleansing gas pipeline for providing a second cleansing gas to the reaction chamber in the cleansing process. The first cleansing gas pipeline and the second cleansing gas pipeline are connected in parallel. The second gas pipeline provides a reactive gas to the reaction chamber in a fabricating process. The first gas pipeline and the second gas pipeline are connected in parallel.	07-17-2014
20140342473	SEMICONDUCTOR PROCESSING METHOD - A method for detecting metal contamination from a film-forming process causing interface traps is described. The film-forming process is performed to form a dielectric film on a wafer. An annealing treatment is performed to reduce the interface traps between the wafer and the dielectric film. Thereafter, the bulk recombination lifetime (BRLT) of the wafer is measured to estimate the amount of the metal contamination.	11-20-2014

Che-Yuan Che, Hsin-Chu TW

Patent application number	Description	Published
20140138750	Jog Design in Integrated Circuits - A device includes an active region in a semiconductor substrate, a gate strip over and crossing the active region, and a jog over the active region and connected to the gate strip to form a continuous region. The jog is on a side of the gate strip. A first contact plug is at a same level as the gate strip, wherein the first contact plug is on the side of the gate strip. A second contact plug is over the jog and the first contact plug. The second contact plug electrically interconnects the first contact plug and the jog.	05-22-2014

Che-Yuan Che, Hsin-Chu City TW

Patent application number	Description	Published
20150087143	Jog Design in Integrated Circuits - A device includes an active region in a semiconductor substrate, a gate strip over and crossing the active region, and a jog over the active region and connected to the gate strip to form a continuous region. The jog is on a side of the gate strip. A first contact plug is at a same level as the gate strip, wherein the first contact plug is on the side of the gate strip. A second contact plug is over the jog and the first contact plug. The second contact plug electrically interconnects the first contact plug and the jog.	03-26-2015

Chieh-Chih Che, Taoyuan County TW

Patent application number	Description	Published
20150204939	MULTIPLE DEFECT DIAGNOSIS METHOD AND MACHINE READABLE MEDIA - A multiple defect diagnosis method includes: receiving a gate-level netlist of a chip, a plurality of test patterns and a plurality of test failure reports; deriving a plurality of seed nets from the gate-level netlist according to the plurality of test patterns and the plurality of test failure reports; utilizing a processor to compute similarity between the plurality of seed nets, and accordingly merging the plurality of seed nets to obtain a single seed net tree; and deriving at least one suspected seed net according to the single seed net tree.	07-23-2015

Chi Ming Che, Hong Kong HK

Patent application number	Description	Published
20080309227	EXTENDED PI-CONJUGATED PLATINUM (II) COMPLEXES - The invention provides organometallic complexes comprising an extended π-conjugated tridentate ligand having a platinum center in which chemical and/or physical properties of the complexes may be modified by changing the structure of the ligands. The complex finds use in devices incorporated into electroluminescent devices, flat panel displays, organic light emitting devices, polymer light emitting devices, transistors, serrors, and lasers.	12-18-2008
20100069345	Lanthanide-porphyrin complexes as anti-tumor agents - The present invention relates to lanthanide porphyrin complexes and their uses as anti-tumor agents. The described complexes show promising cytotoxic properties toward cancer cells in both in vitro and in vivo studies.	03-18-2010
20100314994	Platinum (II) Isoqulinoline-Pyridine-Benzene Based Complexes, Methods for Making Same, and Organic Light-Emitting Diodes Including Such Complexes - This invention provides a class of organometallic complexes comprising a tridentate isoquinoline-pyridine-benzene based ligand, a mono-dentate ligand and a platinum (II) center which show high emission quantum efficiency and good thermal stability. This invention also discloses organometallic complexes in organic light-emitting diode (OLED) including them.	12-16-2010
20110098263	HYDROXY-SUBSTITUTED COLD(III) PORPHYRIN COMPLEXES AS HISTONE DEACETYLASE INHIBITORS - A method for treatment of cancer by inhibiting the activity of histone deacetylase, comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of a gold(III) complex having the structural formula of	04-28-2011
20110282065	SOLID SUPPORTED GOLD NANOPARTICLES, METHODS OF USE THEREOF, AND METHODS FOR MAKING SAME - Solid-supported gold nanoparticles for use as a catalyst for the synthesis of quinolines from anilines and aldehydes using oxygen as an oxidant are provided. Also provided are a method for the preparation of SiO	11-17-2011
20120018711	PLATINUM (II) TETRADENTATE ONCN COMPLEXES FOR ORGANIC LIGHT-EMITTING DIODE APPLICATIONS - Described are novel platinum (II) containing organometallic materials. These materials show green to orange emissions with high emission quantum efficiencies. Using the materials as emitting materials; pure green emitting organic light-emitting diodes can be fabricated. Since the novel platinum (II) containing organometallic materials are soluble in common solvents, solution process methods such as spin coating and printing can be used for device fabrication.	01-26-2012
20150090337	PHOTOVOLTAIC CONVERSION ELEMENT AND PHOTOVOLTAIC CELL - Described herein are organic photovoltaic (OPV) cells using gold complex(es) with as chemical structure of Structure I as active material:	04-02-2015
20150287937	PLATINUM (II) EMITTERS FOR OLED APPLICATIONS - Described herein are novel platinum(II) emitters. These material show high emission quantum efficiency, low self-quenching constant and stable in thermal deposition process. The OLED fabricated from these materials can have pure green emission, high efficiency and low efficiency roll-off.	10-08-2015

Chi-Ming Che, Midlevels West HK

Patent application number	Description	Published
20110230456	Nitridoosmium(VI) Complexes for Treatment of Cancer - The invention relates to nitridoosmium complexes and methods of using these compounds as treatments for cancer.	09-22-2011

Christian Che, Montreal CA

Patent application number	Description	Published
20080299039	Aprotinin Polypeptides for Transporting a Compound Across the Blood-Brain Barrier - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptide for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.	12-04-2008
20090016959	Delivery of antibodies to the central nervous system - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptide derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides. The present invention also relates to the use of these polypeptide for transporting an antibody or antibody fragment across the blood-brain barrier of an individual and in the treatment and diagnosis of neurological diseases.	01-15-2009
20090082277	Potentiation of anticancer agents - The present invention relates to carriers, conjugate and pharmaceutical compositions and their use to increase the potency of drugs and to modify the pharmacokinetics of compounds. More particularly, the present invention relates to conjugates comprising the carrier described herein and their use in the treatment and diagnostic of cancer.	03-26-2009
20100297120	APROTININ-LIKE POLYPEPTIDES FOR DELIVERING AGENTS CONJUGATED THERETO TO TISSUES - Based on our identification of a polypeptide (Angiopep-7) that is efficiently transported to cells such as liver, lung, kidney, spleen, and muscle, the invention provides polypeptides, conjugates including the polypeptides, and methods for treating diseases associated with these cell types. Unlike other aprotinin related polypeptides identified herein (including Angiopep-3, Angiopep-4a Angiopep-4b Angiopep-5, and Angiopep-6) which efficiently cross the blood-brain barrier (BBB), Angiopep-7 is not efficiently transported across the BBB.	11-25-2010

Christian Che, Longueuil CA

Patent application number	Description	Published
20110039785	POLYPEPTIDE-NUCLEIC ACID CONJUGATES AND USES THEREOF - The present invention is directed to polypeptide-nucleic acid conjugates. These conjugates can allow for targeted application of a therapeutic RNAi agent across the blood-brain barrier to treat, for example, a cancer, neurodegenerative disease, or lysosomal storage disorder.	02-17-2011
20110112036	PHARMACEUTICAL COMPOSITIONS OF PACLITAXEL, PACLITAXEL ANALOGS OR PACLITAXEL CONJUGATES AND RELATED METHODS OF PREPARATION AND USE - Pharmaceutical compositions useful for hydrophobic agents paclitaxel, paclitaxel analogs and conjugates thereof (e g ANG1005) which do not contain Cremophor™ The compositions further comprise an optional tonicity agent, a buffering agent a bulking agent and a solubilizmg agent which is not Cremophor™ Methods of preparing said compositions and of said compositions in the treatment of cancer are also included.	05-12-2011
20110171128	APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptides for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.	07-14-2011
20110288009	LEPTIN AND LEPTIN ANALOG CONJUGATES AND USES THEREOF - The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a leptin, a leptin analog, or OB receptor agonist. The compounds of the invention can be used to treat any disease in which increased amounts of leptin are desired, such as metabolic diseases including obesity and diabetes.	11-24-2011
20120135914	ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides having a hydrolyzable covalent bond to a therapeutic agent that includes, etoposide, etoposide 4′-dimethylglycine or doxorubicin. These polypeptide conjugates can be used as vectors to transport the podophyllotoxin derivative across the blood brain barrier (BBB) or into particular cell types such as ovary, liver, lung, or kidney. The invention also relates to pharmaceutical compositions that include the compounds of the invention and to uses thereof in methods of treatment.	05-31-2012
20120141416	MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF - The present invention relates to multimeric (e.g., dimeric, trimeric) forms of peptide vectors that are capable of crossing the blood-brain barrier (BBB) or efficiently entering particular cell types. These multimeric peptide vectors, when conjugated to agents (e.g., therapeutic agents) are capable of transporting the agents across the BBB or into particular cell types. These compounds are therefore particularly useful in the treatment of neurological diseases.	06-07-2012
20120277158	COMPOSITIONS AND METHODS FOR THE TRANSPORT OF THERAPEUTIC AGENTS - The present invention is directed to conjugates that include a polypeptide capable of crossing the blood-brain barrier or entering one or more cell types attached to a transport vector, i.e., a composition capable of transporting an agent (e.g., a therapeutic agent). In certain cases, the polypeptides are directly conjugated to a lipid or polymeric vector to allow targeted application of a therapeutic agent to treat, for example, a cancer, a neurodegenerative disease, or a lysosomal storage disorder.	11-01-2012
20130280281	SHORT AND D-AMINO ACID-CONTAINING POLYPEPTIDES FOR THERAPEUTIC CONJUGATES AND USES THEREOF - The present invention relates to short polypeptides (e.g., fewer than 19 amino acids in length) and longer polypeptides (e.g., 19 or more amino acids in length) having one or more D-amino acids as targeting moieties. These polypeptides, when conjugated to agents (e.g., therapeutic agents or transport vectors) are capable of transporting the agents across the BBB or into particular cell types. In particular, the short polypeptides can include one or more D-amino acids. These compounds are therefore particularly useful in the treatment of neurological diseases or diseases associated with particular cell types, organs, or tissues.	10-24-2013
20150038429	ETOPOSIDE AND DOXORUBICIN CONJUGATES FOR DRUG DELIVERY - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides having a hydrolyzable covalent bond to a therapeutic agent that includes, etoposide, etoposide 4′-dimethylglycine or doxorubicin. These polypeptide conjugates can be used as vectors to transport the podophyllotoxin derivative across the blood brain barrier (BBB) or into particular cell types such as ovary, liver, lung, or kidney. The invention also relates to pharmaceutical compositions that include the compounds of the invention and to uses thereof in methods of treatment.	02-05-2015
20150174266	APROTININ POLYPEPTIDES FOR TRANSPORTING A COMPOUND ACROSS THE BLOOD-BRAIN BARRIER - The invention relates to improvements in the field of drug delivery. More particularly, the invention relates to polypeptides derived from aprotinin and from aprotinin analogs as well as conjugates and pharmaceutical compositions comprising these polypeptides or conjugates. The present invention also relates to the use of these polypeptides for transporting a compound or drug across the blood-brain barrier of a mammal and in the treatment and diagnosis of neurological diseases.	06-25-2015
20150314010	POTENTIATION OF ANTICANCER AGENTS - The present invention relates to carriers, conjugate and pharmaceutical compositions and their use to increase the potency of drugs and to modify the pharmacokinetics of compounds. More particularly, the present invention relates to conjugates comprising the carrier described herein and their use in the treatment and diagnostic of cancer.	11-05-2015

Chun Che, Tainan City TW

Patent application number	Description	Published
20150235954	Barrier Layer and Structure Method - A method for forming a multilayer barrier comprises forming a conductive line over a substrate, depositing a dielectric layer over the conductive line, forming a plug opening in the dielectric layer, forming a multilayer barrier through a plurality of deposition processes and corresponding plasma treatment processes.	08-20-2015

Dock-Chil Che, Osaka JP

Patent application number	Description	Published
20100136705	METHOD FOR MEASURING CONCENTRATION OF PEROXYCARBOXYLIC ACID AND APPARATUS THEREFOR - A method for measuring only a concentration of a peroxycarboxylic acid in an equilibrium mixture containing peroxycarboxylic acid and hydrogen peroxide, comprising the following steps a) and b); a) adding potassium iodide to the equilibrium mixture to cause the generation of iodine and providing the resulting mixture as a measurement sample; and b) measuring the amount of light that goes through the measurement sample to determine only the concentration of a peroxycarboxylic acid.	06-03-2010

Fang-Sik Che, Shiga JP

Patent application number	Description	Published
20150030705	TECHNIQUE AND METHOD FOR PRODUCING FUNCTIONAL MATERIAL ORIGINATED FROM ICE PLANT, AND FUNCTIONAL COMPONENT - The present invention provides a method for producing an ice plant having increased contents of pinitol, β-carotene, vitamin K and proline, said method being characterized by adding a stress to an ice plant during the cultivation of the ice plant; a method for increasing the contents of pinitol, β-carotene, vitamin K and proline, which are functional components contained in an ice plant, said method being characterized by adding a stress to the ice plant during the cultivation of the ice plant; and others.	01-29-2015

Faxing Che, Singapore SG

Patent application number	Description	Published
20100167471	REDUCING WARPAGE FOR FAN-OUT WAFER LEVEL PACKAGING - Fan-out wafer level packaging includes an integrated circuit having a top surface, a bottom surface, a plurality of side surfaces, and a bond pad defined on the top surface. A layer of encapsulant substantially surrounds the side surfaces of the integrated circuit, the layer of encapsulant having a height substantially equal to a height of the integrated circuit. A bump is spaced apart from the integrated circuit, and a redistribution layer electrically couples the bond pad of the integrated circuit to the bump.	07-01-2010
20120244664	REDUCING WARPAGE FOR FAN-OUT WAFER LEVEL PACKAGING - Fan-out wafer level packaging includes an integrated circuit having a top surface, a bottom surface, a plurality of side surfaces, and a bond pad defined on the top surface. A layer of encapsulant substantially surrounds the side surfaces of the integrated circuit, the layer of encapsulant having a height substantially equal to a height of the integrated circuit. A bump is spaced apart from the integrated circuit, and a redistribution layer electrically couples the bond pad of the integrated circuit to the bump.	09-27-2012
20130001795	Wafer Level Package and a Method of Forming the Same - A wafer level package is provided. The wafer level package includes at least one chip with at least one electronic component, and at least one connecting chip with at least one through-silicon via, wherein the at least one through-silicon via is electrically coupled to the at least one chip. Further embodiments relate to a method of forming the wafer level package.	01-03-2013

Gal Won Che, Daejeon KR

Patent application number	Description	Published
20120295357	APPARATUS AND METHOD FOR QUANTIFYING BINDING AND DISSOCIATION KINETICS OF MOLECULAR INTERACTIONS - The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without the influence of a change in the reflective index resulting from a buffer solution by making polarized incident light incident on the binding layer of a bio material, formed in a thin dielectric film, so that the polarized incident light satisfies a p-wave non-reflecting condition and a quantifying method using the same.	11-22-2012

Hong Bo Che, Pohang-City KR

Patent application number	Description	Published
20080209366	METHOD AND APPARATUS FOR ANALYZING CIRCUIT MODEL BY REDUCTION AND COMPUTER PROGRAM PRODUCT FOR ANALYZING THE CIRCUIT MODEL - Provided are a method and apparatus for analyzing a circuit model by reducing, and a computer program product for analyzing the circuit model. The circuit model at least includes independent current source models, resistance models, and capacitance models. Also, the circuit model forms a resistance capacitance (RC) network with independent current sources. The method includes selecting a node to be removed using resistance information and comparing conductance of a capacitor for a given time step and the total conductance of the node. Further, the method includes removing the selected nodes and generating RC elements and independent current sources using adjacent nodes, which maintain the accuracy of node voltages of a circuit reduced in an accuracy order used for entrywise perturbation of the corresponding circuit equation. Moreover, an efficient method of handling the independent current sources while reducing the circuit is provided.	08-28-2008

Hsueh Yi Che, Hualien TW

Patent application number	Description	Published
20090014834	Contact plug structure - A contact plug structure for a checkerboard dynamic random access memory comprises a body portion, two leg portions connected to the body portion and a dielectric block positioned between the two leg portions. Each leg portion is electrically connected to a deep trench capacitor arranged in an S-shape manner with respect to the contact plug structure via a doped region isolated by a shallow trench isolation structure. Preferably, the body portion and the two leg portions can be made of the same conductive material selected from the group consisting of polysilicon, doped polysilicon, tungsten, copper and aluminum, while the dielectric block can be made of material selected from the group consisting of borophosphosilicate glass. Particularly, the contact plug can be prepared by dual-damascene technique. Since the overlapped area between the contact plug structure and a word line can be dramatically decreased, the bit line coupling (BLC) can be effectively reduced.	01-15-2009

Hui-Chung Che, Hsinchu TW

Patent application number	Description	Published
20120278789	COMPUTER IMPLEMENTED APPARATUS FOR GENERATING AND FILTERING CREATIVE PROPOSAL - A computer implemented apparatus for automatically generating and filtering creative proposals is disclosed. Particularly, the computer implemented apparatus automatically generates all possible featured component code sets which corresponding to all possible featured components, and compares them to the prior art code sets which corresponding to the prior objects. Thereby, the novel code sets which corresponding to the novel creative proposals are rapidly filtered out. The computer implemented apparatus comprises a standard component database, a permutation and combination module, a featured component code set database, a prior art code set database, a matching module, a sifting module and an output module.	11-01-2012

Hui-Chung Che, Taipei City TW

Patent application number	Description	Published
20090006379	FILTERING METHOD AND SYSTEM FOR THE CORRELATION BETWEEN TESTING OBJECTS AND PATENTS - In a filtering system for a correlation related to a composing element portfolio of a patent, a plurality of elements are defined by standard element codes and stored. Then composing elements of the patent are defined by the corresponding standard element codes in a standard element depository so as to form the composing element portfolio of the patent to be stored. Then an input module defines a composing element portfolio of the testing object according to the standard element codes. After that, the composing element portfolio input by the input module is matched with the composing element portfolio of each said patent. Afterward, matching result are sorted according to correlation and a sorted result based on the correlation is displayed.	01-01-2009
20090158254	AUTOMATIC CREATIVE PROPOSAL GENERATING AND FILTERING SYSTEM AND MANUFACTURING METHOD THEREOF AND MULTIPLE COMPONENTS COMBINING METHOD - The present invention discloses an automatic method and system for generating and filtering out the innovation proposals. Particularly, it is about a system, which generates all the possible element code sets, compares them to the code sets of existing objects or documents, and then filters out the novel element code sets. The system comprises a standard element depository, a permutation and combination module, a testing object processing module, a matching module, a sifting module, and an output module.	06-18-2009

Hui Je Che, Seoul KR

Patent application number	Description	Published
20150328019	APPARATUS FOR CONTROLLING PROSTHETIC ARM - The present invention provides an apparatus for controlling an artificial hand, including: a head-up display interface portion; and a controller which controls the artificial hand in accordance with an input of the head-up display interface portion, the head-up display interface portion receiving the input based on movement of a user's eyes or pupil.	11-19-2015

Il-Young Che, Daejeon KR

Patent application number	Description	Published
20150160333	METHOD OF CALIBRATING AN INFRASOUND DETECTION APPARATUS AND SYSTEM FOR CALIBRATING THE INFRASOUND DETECTION APPARATUS - In order to calibrate an infrasound detection apparatus including a sound pressure measurement device, a background noise removal device, and a ground vibration velocity measurement device, a step of generating an artificial seismic wave using an artificial seismic source at a position that is spaced a specific distance from the sound pressure measurement device, a step of measuring an atmospheric pressure change and a ground vibration velocity caused by the artificial seismic wave, and a step of comparing the atmospheric pressure change value measured by the sound pressure measurement device with a theoretical atmospheric pressure change value may be performed.	06-11-2015

Jingai Che, Tokyo JP

Patent application number	Description	Published
20160044871	PLANT CULTIVATION METHOD - To provide a technique whereby, in cultivating a crop, factors relating to differentiation into flower buds and leaf buds, sprouting, flowering, and fruiting, growth of young shoots, etc., are regulated. For example, the invention addresses the problem of regulating the growth of a crop so that the leaf buds sprout in tandem and with the sprouting of flower buds and flowering and fruiting are repeated under fresh foliage. [Solution] A plant cultivation method which comprises environmentally stimulating a plant to regulate differentiation into flower buds and/or differentiation into leaf buds. In a typical embodiment, the plant is help in an environment at a temperature of 16-40° C. at a photoperiod of 8-12 hours immediately after harvesting fruits. As another environmental stimulus, the plant is held in, for example, an environment at a temperature of 3-7° C. As still another environmental stimulus, the plant is held in, for example, an environment at a temperature of 16-23° C. at a photoperiod of 8-11 hours.	02-18-2016

Khac Nguyen Che, Brussels BE

Patent application number	Description	Published
20140033836	CUTTING APPARATUS - Described herein is a cutting apparatus (	02-06-2014
20140311805	METHODS AND APPARATUS FOR CORING - Described herein is an inner tube for a core barrel which has a structure adapted to retain lubricant for lubricating a sampled core. In one embodiment, the internal surface of the inner tube includes a plurality of alveoli in which lubricant is retained.	10-23-2014
20150083497	HYDRAULIC ACTIVATION OF MECHANICALLY OPERATED BOTTOM HOLE ASSEMBLY TOOL - A method of hydraulically activating a mechanically operated wellbore tool in a bottom hole assembly includes: holding moveable elements of the wellbore tool in an unactivated position using a shear pin; inserting one or more drop balls into a drilling fluid; and flowing the drilling fluid with the drop balls to a flow orifice located in or below the wellbore tool. The flow orifice is at least partially plugged with the drop balls to restrict fluid flow and correspondingly increases the hydraulic pressure of the drilling fluid. The hydraulic pressure is increased to a point beyond the rating of the shear pin, thereby causing the shear pin to shear and allowing the moveable elements of the tool to move to an activated position.	03-26-2015
20150330182	Hydraulic Activation of Mechanically Operated Bottom Hole Assembly Tool - A method of hydraulically activating a mechanically operated wellbore tool in a bottom hole assembly includes: holding moveable elements of the wellbore tool in an unactivated position using a shear pin; inserting one or more drop balls into a drilling fluid; and flowing the drilling fluid with the drop balls to a flow orifice located in or below the wellbore tool. The flow orifice is at least partially plugged with the drop balls to restrict fluid flow and correspondingly increases the hydraulic pressure of the drilling fluid. The hydraulic pressure is increased to a point beyond the rating of the shear pin, thereby causing the shear pin to shear and allowing the moveable elements of the tool to move to an activated position.	11-19-2015

Lihua Che, Incheon KR

Patent application number	Description	Published
20110021442	CELL PREAMBLE RUNX3 RECOMBINANT PROTEINS, POLYNUCLEOTIDES ENCODING THE SAME, AND ANTICANCER COMPOSITIONS INCLUDING THE SAME - The present invention discloses cell permeable RUNX3 recombinant proteins where a Macromolecule Transduction Domain (MTD) is fused to a tumor and metastasis suppressor RUNX3. Also disclosed are polynucleotides encoding the cell permeable RUNX3 recombinant proteins, an expression vector containing the cell permeable RUNX3 recombinant protein, and a pharmaceutical composition for preventing metastasis which contains the cell permeable RUNX3 recombinant protein as an effective ingredient. The cell permeable RUNX3 recombinant proteins of the present invention can induce the reactivation of TGF-β signal transduction pathway which causes cell cycle arrest by efficiently introducing a tumor and metastasis suppressor RUNX3 into a cell. Therefore, the cell permeable RUNX3 recombinant proteins of the present invention can be effectively used as an anticancer agent capable of preventing cancer growth and metastasis by suppressing the proliferation, differentiation, and migration of cancer cells.	01-27-2011

Shenglei Che, Tokyo JP

Patent application number	Description	Published
20080236706	METHOD OF PRODUCING MNZN-BASE FERRITE - Firing is carried out such that for operation of a partial pressure of oxygen and temperature at the high-temperature holding operation phase and cooling operation phase, the following equilibrium relation equation (1) indicative of an equilibrium relation of a partial pressure of oxygen (PO	10-02-2008

Xiangguo Che, Daegu KR

Patent application number	Description	Published
20160000938	REAGENT FOR DIAGNOSIS OF OSTEOARTHRITIS COMPRISING PEPTIDE PROBE OF APOPEP-1 - Disclosed is a reagent for diagnosing osteoarthritis or predicting the prognosis of osteoarthritis, the reagent containing a peptide having the amino acid sequence (CQRPPR) of SEQ ID NO: 1 as an active ingredient. The present peptide can be used to accurately diagnose osteoarthritis in its early stage based on the molecular imaging technique. The present peptide has a small molecular weight, and thus has advantages of fast clearance from the blood, effective permeation into the tissue, low immunogenicity, and low-production cost. Further, the present reagent can diagnose osteoarthritis in its early stage in which the destruction of cartilage is in a reversible phase and thus can be recovered to a normal state, thereby significantly contributing to effective treatment of osteoarthritis.	01-07-2016

Yanlong Che, Ashigarakami-Gun JP

Patent application number	Description	Published
20120078189	NEEDLE ARRAY TRANSDERMAL ABSORPTION SHEET AND METHOD FOR MANUFACTURING NEEDLE ARRAY TRANSDERMAL ABSORPTION SHEET - A needle array transdermal absorption sheet to be attached onto a skin for supplying a drug into the skin, includes: a plurality of needle portions each having a tapered shape, each of the needle portions including a needle having a conical or pyramidal shape and a body part which has a columnar shape and whose end surface is connected to a base of the needle; a sheet portion having a flat-plate shape; and a plurality of frustum portions each having a frustum shape, the frustum portions which are arranged on a surface of the sheet portion in a manner that perimeters of larger bases of adjacent frustum portions are in contact with each other on the surface of the sheet portion, and smaller bases of which are respectively connected to the body parts of the needle portions.	03-29-2012
20150196746	NEEDLE ARRAY TRANSDERMAL ABSORPTION SHEET AND METHOD FOR MANUFACTURING NEEDLE ARRAY TRANSDERMAL ABSORPTION SHEET - A needle array transdermal absorption sheet to be attached onto a skin for supplying a drug into the skin, includes: a plurality of needle portions each having a tapered shape, each of the needle portions including a needle having a conical or pyramidal shape and a body part which has a columnar shape and whose end surface is connected to a base of the needle; a sheet portion having a flat-plate shape; and a plurality of frustum portions each having a frustum shape, the frustum portions which are arranged on a surface of the sheet portion in a manner that perimeters of larger bases of adjacent frustum portions are in contact with each other on the surface of the sheet portion, and smaller bases of which are respectively connected to the body parts of the needle portions.	07-16-2015
20150238413	METHOD FOR MANUFACTURING TRANSDERMAL-ABSORPTION SHEET - A method is provided which enables a drug to be concentrated at needle-like protruding portions and which further allows transdermal-absorption sheets to be manufactured at high production efficiency. The method repeats a step of feeding a drug-containing solution from a liquid feeding apparatus to a mold and filling needle-like recessed portions with the drug-containing solution through a nozzle aligned over the needle-like recessed portions in a state where the nozzle and a front surface of the mold are brought into contact with each other, and a step of moving the liquid feeding apparatus relative to the mold in a state where the nozzle and the front surface of the mold are brought into contact with each other. Thus, the two-dimensionally arranged needle-like recessed portions are filled with the drug-containing solution.	08-27-2015
20150238434	TRANSDERMAL ABSORPTION SHEET, AND MANUFACTURING METHOD FOR THE SAME - A transdermal absorption sheet and a manufacturing method for the transdermal absorption sheet includes a laminating step of forming a multilayer film with a viscosity difference by forming, on a support, a lower layer containing a first transdermal absorption material and an upper layer containing a drug and a second transdermal absorption material and having a lower viscosity than the lower layer, a filling step of filling needle-like recessed portions corresponding to inverted needle-like protruding portions with a solution of the transdermal absorption material by pressing a mold in which the needle-like recessed portions are arranged in a two-dimensional array, against a surface of the multilayer film supported by the support to allow the multilayer film to flow, a solidifying step of solidifying the multilayer film with the mold pressed against the surface of the multilayer film, and a peeling-off step of peeling the solidified multilayer film from the mold.	08-27-2015
20150238743	MOLDING COMPACT, AND MANUFACTURING METHOD FOR TRANSDERMAL ABSORPTION SHEET - A molding compact for forming a transdermal absorption sheet on which a needle-shaped protruding part is arranged is a molding compact that is a laminate of: a first member having a needle-shaped recessed part formed on a front surface thereof, the needle-shaped recessed part being an inverse of the needle-shaped protruding part; a second member provided on a back surface of the first member, the second member being composed of a waterproof and moisture-permeable material; and a third member provided on a back surface of the second member, the third member being composed of a rigid body. Provided are a molding compact that makes it possible to prevent leakage of a drug-containing solution filled into the needle-shaped recessed part, and a manufacturing method for a transdermal absorption sheet using the molding compact.	08-27-2015

Yanlong Che, Odawara-Shi JP

Patent application number	Description	Published
20080223723	METHOD FOR MANUFACTURING MASTER INFORMATION CARRIER FOR MAGNETIC TRANSFER - There is provided a method for manufacturing a high quality master information carrier for magnetic transfer, the method preventing the metallic disk formed by electroforming from coming off from the conduction ring and decreasing the distortion of the master information carrier. A conduction ring connected to a cathode is arranged on a matrix and electroforming is performed with the conduction ring being smaller in bore diameter than a presser ring for fixing the conduction ring and the matrix.	09-18-2008
20080237912	METHOD OF PRODUCING STAMPER FOR OPTICAL RECORDING MEDIUM, METHOD OF PRODUCING SUBSTRATE, METHOD OF PRODUCING OPTICAL RECORDING MEDIUM, AND APPARATUS FOR PRODUCING STAMPER FOR OPTICAL RECORDING MEDIUM - In a method of producing a stamper for roughening a substrate of an optical recording medium, a masking treatment is carried out prior to a blasting treatment, whereby a second pit forming site of a metal plate is protected such that the second pit forming site is not broken in the following blasting treatment. A mask of an adhesive sheet is attached to the second pit forming site in the masking treatment, and then a part of one major surface of the metal plate, exposed between the mask, is roughened in the blasting treatment. An original stamper of the metal plate, having a partly roughened major surface, is obtained by the blasting treatment.	10-02-2008
20090008257	METHOD OF PRODUCING STAMPER FOR OPTICAL RECORDING MEDIUM, METHOD OF PRODUCING SUBSTRATE, AND METHOD OF PRODUCING OPTICAL RECORDING MEDIUM - A method of producing a stamper for roughening a substrate of an optical recording medium contains the steps of placing a conductive ring having a hole at the center thereof on a major surface of an original metal plate, electroforming a metal layer over a portion of the metal plate exposed in the hole of the conductive ring, an inner end-face of the conductive ring, and a portion of a major surface of the conductive ring, and entirely or partly roughening a major surface of the metal layer by a blasting treatment to obtain an original stamper.	01-08-2009

Yu-Chi Che, Hsinchu County TW

Patent application number	Description	Published
20150179392	Method and Apparatus for Electron Beam Lithography - A system using an energy beam to expose patterns on a wafer includes first mirror elements, a multiplexer element, and second mirror elements. The first and second mirror elements are dynamically controlled to reflect the energy beam to the wafer. The first mirror elements are configured in a first chain having a first data input and a first data output. The multiplexer element includes a second data input, a third data input, a select input, and a second data output. The third data input is coupled to the first data output. The second mirror elements are configured in a second chain having a fourth data input.	06-25-2015

Yung-Chien Che, Kaohsiung City TW

Patent application number	Description	Published
20140349618	System for Actively Notifying Instant Messages and Locations in a Certain Area and Method Therefor - A system for actively notifying instant messages and locations in a certain area and a method therefor contain a controlling device function module for judging messages and functions transmitted to a processing device function module of a at least one service device function module from a back-site device function module. The back-site device function module chooses the messages of the processing device function module. The at least one service device function module transmits the messages to a user handheld device from the back-site device function module, and the at least one service device function module includes a WiFi device and a processing device function module. The user handheld device transmits a regional location message, a language using system code, and a group identification code of the user handheld device to the at least one service device function module in the certain area.	11-27-2014
20150188390	ELECTRICITY GENERATING DEVICE - An electricity generating device including a base having a track, an electricity generating mechanism and a kinetic mechanism. The electricity generating mechanism includes a contact pressure assembly disposed on the track, and an electricity generating module connected to the contact pressure assembly. The electricity generating module is configured to convert mechanical energy generated by the contact pressure assembly into electrical energy. The kinetic mechanism includes at least one slider disposed on the track, and a drive assembly connected to the slider for driving the slider to continuously move along the track. The slider repeatedly rolls over the contact pressure assembly when driven by the drive assembly to continuously move along the track.	07-02-2015

Zhong Min Che, Seoul KR

Patent application number	Description	Published
20110104741	Screening Method for Inhibitors of Cancer Cell Invasion and Screening System Thereof - This invention relates to a screening method for an inhibitor to cancer cell invasion, comprising the steps of: (a) co-culturing cancer cells and a carcinoma-associated fibroblasts (CAFs) in a multi-chamber containing a upper-chamber, a lower-chamber and a porous filter separating the upper-chamber from the lower-chamber; in which each cancer cells and CAFs is inoculated into the upper-chamber and the lower-chamber of the multi-chamber, and then a candidate is added to the upper-chamber; and (b) measuring the number of cancer cells passing the porous filter. According to the screening system and screening method using the same, the inhibitor to cancer cell invasion is able to be screened in a high-throughput manner.	05-05-2011