Patent application number | Description | Published |
20080242600 | Backbone Cyclized Melanocortin Stimulating Hormone (Alpha Msh) Analogs - Backbone cyclized peptides which are α-melanocortin stimulating hormone (αMSH) analogs, having improved Melanocortin-4 receptor agonist activity are disclosed. The backbone cyclized peptide analogs disclosed possess unique and superior properties over other analogs, such as metabolic stability, increased oral bioavailability, improved intestinal permeability and pharmacological activity in-vivo. Pharmaceutical compositions that include the backbone cyclized αMSH analogs, and methods of using such compositions for the treatment of metabolic disorders including obesity are also disclosed. | 10-02-2008 |
20080312140 | Compositions and Methods for Preventing or Treating Hiv Infection - The present invention is directed to compositions and methods of preventing for treating a retroviral infection, more particularly an HIV (human immunodeficiency virus) infection, and even more particularly an HIV-1 infection. The compositions and methods involve molecules that mimic the active site of the human CD4 protein. | 12-18-2008 |
20100022499 | HETEROCYCLIC COMPOUNDS, COMBINATORIAL LIBRARIES THEREOF AND METHODS OF SELECTING DRUG LEADS - Heterocyclic compounds having a relatively flexible backbone are used to create combinatorial libraries that permit screening for lead compounds and selection of drug candidates for a variety of uses in human and veterinary medicine as well as in agriculture. The compounds of the library generally differ in ring size and chirality of substituents on the ring. Also disclosed are methods for providing and screening these libraries, preferably in an automated or computerizable manner, such as by using a computer program to virtually screen the compounds in order to identify those that are predicted to have bioactive conformations that should give rise to desirable biological effects. | 01-28-2010 |
20120270774 | MACROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND METHODS FOR PREVENTING OR TREATING HIV INFECTION - The present invention relates to backbone cyclized CD-4 mimetics and to compositions and methods comprising them for preventing and treating viral infection. In particular, the present invention relates to orally bio-available compounds and formulations for prevention and treatment of human HIV-1 infection. | 10-25-2012 |
20140212444 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE - The present invention provides compositions and methods for inducing an immune response in a subject. In particular, the present invention provides compositions comprising immunostimulatory ligands (ISL) and methods of inducing an immune response in a subject therewith. Compositions and methods of the present invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., vaccination)) and research applications. | 07-31-2014 |
20140336127 | Stabilized Peptide Helices For Inhibiting Dimerization Of Chemokine C Motif Receptor 2 (CCR2) - Peptide helices stabilized by backbone cyclization which are capable of inhibiting dimerization of the Chemokine (C-C motif) receptor 2 (CCR2), as well as pharmaceutical compositions including such backbone cyclized peptide helices. Use of pharmaceutical compositions and peptide helices in treatment of Multiple Sclerosis (MS) and other diseases associated with CCR2 activation. | 11-13-2014 |
20150072933 | NOVEL SEQUENCES FOR THE CONTROL OF REPRODUCTION IN FISH - The present invention relates to novel peptide sequences, compositions and methods for controlling fish reproduction. More particularly, the invention provides novel Neurokinin B peptides NKF and NKB and analogues thereof that regulate reproduction in fish. The invention further provides preprohormone thereof comprising at least one of a first peptide fragment of the amino acid sequence X | 03-12-2015 |
Patent application number | Description | Published |
20120125020 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING USING PHOTOVOLTAIC-THERMAL (PVT) MODULES - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-24-2012 |
20120125021 | DESICCANT AIR CONDITIONING METHODS AND SYSTEMS USING EVAPORATIVE CHILLER - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-24-2012 |
20120125031 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-24-2012 |
20120125405 | PHOTOVOLTAIC-THERMAL (PVT) MODULE WITH STORAGE TANK AND ASSOCIATED METHODS - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-24-2012 |
20120125581 | HEAT EXCHANGER AND ASSOCIATED METHODS - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-24-2012 |
20120131934 | WATER RECOVERY METHODS AND SYSTEMS - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120131937 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120131938 | AIR CONDITIONING SYSTEM WITH INTEGRATED SOLAR INVERTER - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120131939 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120131940 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING WITH COMBUSTION CONTAMINANT FILTERING - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120132513 | DESALINATION METHODS AND SYSTEMS - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 05-31-2012 |
20120186281 | METHODS AND SYSTEMS FOR DESICCANT AIR CONDITIONING USING FLUIDS HEATED OR COOLED BY A SOLAR THERMAL SYSTEM - Methods and systems are provided for air conditioning, capturing combustion contaminants, desalination, and other processes using liquid desiccants. | 07-26-2012 |
Patent application number | Description | Published |
20120185184 | SYSTEM AND METHOD FOR IDENTIFYING LIKELY GEOGRAPHICAL LOCATIONS OF ANOMALIES IN A WATER UTILITY NETWORK - A computerized method for determining one or more statistically likely geographical locations of an anomaly in a region or zone of a water utility network, the water utility network comprising at least a network of pipes for delivering water to consumers and a plurality of meters positioned within the water utility network including a plurality of meters capturing data regarding the water delivering within the region or zone of the anomaly, the method comprising. The method includes receiving anomaly event data, the anomaly event data representing an indication of an anomaly occurring or having occurred within a region or zone of the water utility network, the anomaly event data being associated with meter data produced by one or more of the meters. The method also includes performing a plurality of tests on the anomaly event data each designed to statistically determine a likely geographical location of the anomaly within the region or zone, the performance of each test producing a result. The results of the plurality of tests to generate scores for the determined likely locations for the anomaly are combined. The one or more of the determined likely locations are presented to a user. | 07-19-2012 |
20130211797 | SYSTEM AND METHOD FOR ANALYZING GIS DATA TO IMPROVE OPERATION AND MONITORING OF WATER DISTRIBUTION NETWORKS - A computerized method for modeling a utility network. The method includes retrieving geographical information system (GIS) data, asset management data, and sensor archive data of one or more assets of the utility network. The method also includes generating one or more mathematical elements from the one or more assets and creating probable connections between the one or more mathematical graph elements based on the GIS and asset data. A mathematical graph is generated based on the probable connections, the mathematical graph including one or more asset characteristics of the one or more assets. Analysis is performed on the utility network using the mathematical graph and the mathematical graph data is stored for use by other systems within the utility network. | 08-15-2013 |
20130332090 | SYSTEM AND METHOD FOR IDENTIFYING RELATED EVENTS IN A RESOURCE NETWORK MONITORING SYSTEM - A computerized method for detecting related events in a water monitoring system. The method includes receiving event data from a plurality of sensors in a water network. The method also includes identifying at least two candidate events from the event data as being candidate events which are likely to constitute part of a common anomaly event, the candidate events each being substantially anomalous. An event combination rule is selected. One or more event characteristics are compared between the at least two candidate events based on the event combination rule. The at least two candidate events are determined whether they are related and associated with a common event causing the at least two candidate events on the basis of the comparison. The determination of the at least two candidate events are related and associated with a common event is reported to a user via a user interface. | 12-12-2013 |
20130332397 | METHOD FOR LOCATING A LEAK IN A FLUID NETWORK - Methods and systems are described for providing cost effective leak detection in a fluid network. Step testing procedures are represented by decision trees and associated expected costs are calculated. Selection of step testing procedures is optimized for low expected cost. The total expected cost rate for a network configuration may be calculated from the rate of leak occurrence and the optimal expected costs associated therewith. Network configuration changes may be recommended by optimizing for total expected cost rate for a fluid network. | 12-12-2013 |
20140152465 | SYSTEM AND METHOD FOR IDENTIFYING LIKELY GEOGRAPHICAL LOCATIONS OF ANOMALIES IN A WATER UTILITY NETWORK - A computerized method for determining one or more statistically likely geographical locations of an anomaly in a region or zone of a water utility network, the water utility network comprising at least a network of pipes for delivering water to consumers and a plurality of meters positioned within the water utility network including a plurality of meters capturing data regarding the water delivering within the region or zone of the anomaly, the method comprising. The method includes receiving anomaly event data, the anomaly event data representing an indication of an anomaly occurring or having occurred within a region or zone of the water utility network, the anomaly event data being associated with meter data produced by one or more of the meters. The method also includes performing a plurality of tests on the anomaly event data each designed to statistically determine a likely geographical location of the anomaly within the region or zone, the performance of each test producing a result. The results of the plurality of tests to generate scores for the determined likely locations for the anomaly are combined. The one or more of the determined likely locations are presented to a user. | 06-05-2014 |