Chackerian
Alissa A. Chackerian, Menlo Park, CA US
Patent application number | Description | Published |
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20100291084 | USE OF IL-23 ANTAGONISTS FOR TREATMENT OF INFECTION - Methods and compositions comprising antagonists of IL-23 are provided for the treatment of infections, such as chronic bacterial, viral and fungal infections. | 11-18-2010 |
Alissa A. Chackerian, Sunnyvale, CA US
Patent application number | Description | Published |
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20120207752 | METHODS FOR MODULATING IL-33 ACTIVITY - Provided herein are methods of modulating IL-33 activity, e.g., for the purpose of treating immune diseases and conditions, as well as methods of screening for compounds capable antagonizing IL-33 signaling. | 08-16-2012 |
20130337470 | METHODS FOR DETERMINING DIFFERENCES IN ALPHA-4 INTEGRIN ACTIVITY BY CORRELATING DIFFERENCES IN sVCAM AND/OR sMadCAM LEVELS - Provided herein is a method of monitoring the change of the alpha-4 integrin activities in an individual by correlating with the soluble vascular cell adhesion molecule (sVCAM) and/or soluble mucosal addressin cell adhesion molecule (sMAd-CAM) levels. Particularly, this method can be used, for example, to evaluate the pharmacokinetics and pharmacodynamics (PK/PD) of an alpha-4 integrin inhibitor used to treat a disease associated with pathological or chronic inflammation. | 12-19-2013 |
20140105887 | METHODS FOR MODULATING IL-33 ACTIVITY - Provided herein are methods of modulating IL-33 activity, e.g., for the purpose of treating immune diseases and conditions, as well as methods of screening for compounds capable antagonizing IL-33 signaling. | 04-17-2014 |
20140147442 | USE OF IL-23 ANTAGONISTS FOR TREATMENT OF INFECTION - Methods and compositions comprising antagonists of IL-23 are provided for the treatment of infections, such as chronic bacterial, viral and fungal infections. | 05-29-2014 |
Bryce C. Chackerian, Albuquerque, NM US
Patent application number | Description | Published |
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20130302371 | Immunogenic Respiratory Syncytial Virus Glycoprotein-Containing VLPs and Related Compositions, Constructs, and Therapeutic Methods - The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of Respiratory Syncytial Virus (RSV) infections and related disorders, including bronchiolitis and viral pneumonia. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against RSV. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against RSV infection, confer immunity against RSV infection, protect against RSV infection, and reduce the likelihood of infection by RSV infection. | 11-14-2013 |