Patent application number | Description | Published |
20090281464 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 11-12-2009 |
20100331741 | Medical treatment system including an ancillary medical treatment apparatus with an associated data storage medium - A medical treatment system includes an electronic controller with a medical treatment apparatus, a data reader, an ancillary treatment apparatus used with the electronic medical treatment apparatus and a data storage medium associated with the ancillary treatment apparatus. The controller is configured to receive information from the data storage medium, and to control the medical treatment apparatus with medical treatment parameters compatible with the desired medical treatment and the ancillary treatment apparatus. | 12-30-2010 |
20110034832 | Usage of Extracorporeal and Intracorporeal Pressure Shock Waves in Medicine - A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment. | 02-10-2011 |
20110087157 | Use of Pressure Waves for Stimulation, Proliferation, Differentiation and Post-Implantation Viability of Stem Cells - Stem cells are proliferated with the application of acoustic pressure waves, including cambium cells of periosteum treated in-vivo with acoustic pressure waves. Following harvesting and viability assessment of in-vivo or in-vitro proliferated stem cells, acoustic pressure waves are applied to enhance in-vivo or in-vitro differentiation either before or after implantation of the stems cells to an organism. Acoustic pressure waves also stimulate an implantation site to enhance viability and to grow desired tissue. | 04-14-2011 |
20140088465 | Extracorporeal Pressure Shock Wave Devices with Reversed Applicators and Methods for Using these Devices - A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment. | 03-27-2014 |
20140243715 | Extracorporeal Pressure Shock Wave Devices with Multiple Reflectors and Methods for Using these Devices - A shock wave applicator includes a housing multiple reflectors with shock wave generators projecting into a shared cavity. The multiple shock wave generators are able to produce a variety of shockwave focal volumes and wave fronts for medical treatment. | 08-28-2014 |
Patent application number | Description | Published |
20080261967 | Modulators of Central Nervous System Neurotransmitters - Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents. | 10-23-2008 |
20100159596 | SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION - Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof: | 06-24-2010 |
20110281356 | COMPOUNDS FOR STEM CELL DIFFERENTIATION - Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I: | 11-17-2011 |
20130123253 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS - Disclosed are agents having pharmacological activity against cellular receptors and intracellular signaling, particularly receptors and signaling pathways of central nervous system (CNS) neurotransmitters. Also disclosed are related methods and compositions for the treatment or prevention of diseases or disorders using the agents. | 05-16-2013 |
20130157947 | COMPOUNDS FOR STEM CELL DIFFERENTIATION - Small molecule compounds and methods for stem cell differentiation are provided herein. An example of a class of compounds that may be used to practice the methods disclosed herein is represented by enantiomerically pure isomers of compounds of Formula I: | 06-20-2013 |
20130177535 | WNT INHIBITORS FOR HUMAN STEM CELL DIFFERENTIATION - Methods and small molecule compounds for stem cell differentiation and treatment of animals with diseases are provided. One example of a class of compounds that may be used is represented by the compound of Formula I and II: | 07-11-2013 |
20130190258 | COMPOUNDS FOR INHIBITION OF CANCER CELL PROLIFERATION - Methods and small molecule compounds for inhibition of cancer cell proliferation are provided. One example of a class of compounds that may be used is represented by the compound of Formula I or a pharmaceutically acceptable salt, N-oxide or solvate thereof, wherein A, B, D, E, F, G, I, J, R, R | 07-25-2013 |
Patent application number | Description | Published |
20090263492 | Diagnostic Methods and Genetic Markers for Alzheimer Disease - Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful for such treatment. Also disclosed are methods for predicting the efficacy of a drug candidate for the treatment of a CNS disorder. The technology is also applicable to drug discovery for use in animal models of neurodegenerative diseases. | 10-22-2009 |
20100190728 | Synthesis Of Metabolically Stable Analgesics, Pain Medications And Other Agents - Disclosed are analgesic-related compositions and methods of using the compositions for modulation of analgesic receptor activity. The compositions and methods are useful for reducing pain, as well as for therapeutic intervention of addictions or other diseases or disorders amenable to treatment or prophylaxis by modulation of analgesic receptor signaling. | 07-29-2010 |
20100298345 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER - Disclosed are nicotine-related compounds that selectively inhibit cytochrome P-450 2A6 (CYP2A6), selectively inhibit cytochrome P-450 2A13 (CYP2A13), and/or selectively modulate a nicotinic acetylcholine receptor (nAChR). Also disclosed are pharmaceutical compositions comprising a compound of the invention, as well as methods of using the pharmaceutical compositions for treating or preventing a disease or disorder associated with nicotine-ingestion, or a disease or disorder amenable to treatment by selective modulation of nAChRs. | 11-25-2010 |
20110236931 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE - Provided is a method to identify OP-adducted biomarkers of OP exposure as well as compounds containing OPs that can provide OP adducts. | 09-29-2011 |
20120040976 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE - Disclosed are methods for identifying individuals suffering from a CNS disorder (including Alzheimer's Disease, ALS, behavioral disorders, and the like) that could be treated with a CNS drug with greater therapeutic efficacy and lower side effects and the compounds useful for such treatment. Also disclosed are methods for predicting the efficacy of a drug candidate for the treatment of a CNS disorder. The technology is also applicable to drug discovery for evaluation in animal models of neurodegenerative diseases. | 02-16-2012 |
20120196905 | SYNTHETIC COMPOUNDS AND METHODS TO DECREASE NICOTINE SELF-ADMINISTRATION - Methods and small molecule compounds for smoking and CNS disease harm reduction are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate or solvate thereof: | 08-02-2012 |
20140051712 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION - The invention describes pharmaceutical agents capable of crossing the blood brain barrier to protect against organophosphate pesticides and nerve agents or other electrophiles by reactivating inhibited cholinesterase (i.e., acetylcholinesterase and butyrylcholinesterase) and other proteins in the peripheral and central nervous system. | 02-20-2014 |
Patent application number | Description | Published |
20100261640 | SOLUBLE AND MEMBRANE ANCHORED FORMS OF LASSA VIRUS SUBUNIT PROTEINS - The invention discloses compositions comprising soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins. This invention further relates to diagnostic and preventative methods using these compositions. Preventative methods include preparation of vaccines, as well as factors (e.g. small molecules) that inhibit LASV infectivity. Further, the invention relates to diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses. | 10-14-2010 |
20140377740 | SOLUBLE AND MEMBRANE-ANCHORED FORMS OF LASSA VIRUS SUBUNIT PROTEINS - Soluble and membrane-anchored forms of Lassa virus (LASV) glycoprotein 1 (GP1), glycoprotein 2 (GP2), the glycoprotein precursor (GPC), the nucleocapsid protein (NP), and the nucleic acids encoding these proteins are disclosed, as well as diagnostic and preventative methods using these compositions. Also disclosed are methods including preparation of vaccines, factors (e.g. small molecules) that inhibit LASV infectivity, and diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses. | 12-25-2014 |
Patent application number | Description | Published |
20130124229 | SYSTEM AND METHOD FOR SECURE SELF REGISTRATION WITH AN INSURANCE PORTAL - Systems and methods are disclosed herein for processing a first-time registration request for electronic access to a plurality of computerized insurance services. A network interface is configured to communicate with the plurality of computerized insurance services by interfacing with a plurality of disparate information platforms and communicating with a user computing device. A memory stores a portal module, a profile module, and a security module, each in the form of computer executable instructions, which, when executed by a processor, cause the system to receive a user identity, a first-time registration request of the user identity, and one or more secure information items associated with the user identity from the user computing device, determine a verification score for the user identity based on the one or more secure information items, and selectively register the user identity with a plurality of the computerized insurance services based on the verification score. | 05-16-2013 |
20130125211 | SYSTEM AND METHOD FOR PROVIDING DYNAMIC INSURANCE PORTAL TRANSACTION AUTHENTICATION AND AUTHORIZATION - Systems and methods are disclosed herein for managing electronic access to a plurality of computerized insurance services. A network interface is configured to receive a user identity provided by a user remote to the system and an access request from the user to access a selected computerized insurance service from the plurality of computerized insurance services. A memory stores computer executable instructions which, when executed by a processor, cause the system to determine a set of access rights for the user based on the user identity and an insurance-related role associated with the user identity and allow the user to access the selected computerized insurance service according to the access request only if the access requested is included in the determined set of access rights. At least two of the computerized insurance services are implemented on substantially different information platforms. | 05-16-2013 |
20140172740 | SYSTEM AND METHOD FOR UNIFIED CUSTOMER COMMUNICATIONS - A publishing system and method for distributing electronic and paper documents for multiple financial service products is disclosed. The system includes a memory device configured to store policy information for the multiple financial service products associated with each of a plurality of clients to store communication settings for each of the multiple financial service products, the communication settings including contact information and notification preferences, and to store document templates. The system includes a processor configured to process a request for generating notification/alert documents, to generate notification/alert documents by modifying the document templates based on the policy information and communication settings and to store the notification/alert documents in the memory device, and to determine whether the notification/alert documents were not received or received in error. The system includes a transmitter configured to transmit the notification/alert documents based on the communication settings. | 06-19-2014 |
20140173001 | SYSTEM AND METHOD FOR DISTRIBUTING ELECTRONIC AND PAPER DOCUMENTS AS PER CUSTOMER CONSENT - A system for enterprise distribution of electronic and paper documents for multiple insurance products is disclosed. The system including a memory device to store policy information for multiple insurance products associated with each of a plurality of clients. The memory device stores document delivery settings, including contact information and notification/alert preferences. The system includes a processor to generate document delivery questions relating to the preferred medium for notification and alert documents. The system includes a receiver to receive responses to the document delivery questions. The processor generates consent questions and updates the document delivery settings based on the response to the document delivery questions and the consent questions. The system may also include a transmitter to transmit a message to the clients notifying them of the change in the document delivery settings and to transmit a message notifying a source system of the change in document delivery settings. | 06-19-2014 |
20150121475 | SYSTEM FOR PROVIDING DYNAMIC PORTAL TRANSACTION AUTHENTICATION AND AUTHORIZATION - Systems and methods are disclosed herein for managing electronic access from remote devices to a plurality of computer platforms. The system includes a processor, a network interface, and a memory. The network interface is configured to receive a user identity provided by a device remote to the system and an access request from the device to access a selected computer platform from the plurality of computerized platforms. The memory stores computer executable instructions which, when executed by the processor, cause the system to determine a set of access rights for the device based on the user identity and a role associated with the user identity, as related to the selected computerized platform. The computer executable instructions, when executed by the processor, further cause the system to allow the user to access the selected platforms according to the access request only if the access requested is included in the determined set of access rights. | 04-30-2015 |
Patent application number | Description | Published |
20100184838 | Compositions and methods for retinal transduction and photoreceptor specific transgene expression - Adenovirus (Ad) vectors are here provided for treatment of ocular tissues as are suitable methods to transduce photoreceptor (PR) cells, the tissue associated with degeneration. Expression from CMV or chicken beta actin (CBA) promoters in neural retina were compared, and CBA was found to be 173-fold more potent than CMV. Further, the RGD domain in Ad penton was found to play a key role in RPE tropism. Deletion of the RGD domain coupled with the CBA promoter permitted transgene expression in neural retina approximately 667-fold more efficiently than with prior Ad5 vectors. Use of Ad vectors in combination with a 4.7 kb rhodopsin promoter enabled transgene expression exclusively in photoreceptor cells in vivo. | 07-22-2010 |
20100209447 | Methods of making and using a cell penetrating peptide for enhanced delivery of nucleic acids, proteins, drugs, and adenovirus to tissues and cells, and compositions and kits - A peptide-POD with ability to penetrate and deliver fluorophores, siRNA, DNA and quantum dots to cells in culture and retinal and ocular tissues in vivo is provided herein. POD couples to adenovirus vectors, enhancing tropism for certain cells, potentially providing a safer and more efficacious method to deliver molecules to ocular and other tissues in vivo. POD constructs are therapeutic delivery vehicles for treating cells and tissues, including ocular cells and tissues suffering from retinal degeneration. | 08-19-2010 |
20110015136 | humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration - Methods and compositions for treating a subject having age-related macular degeneration (AMD), methods of assaying human macular degeneration (MD), and methods and kits for assaying potential therapeutic agents for treatment of human MD are provided herein. | 01-20-2011 |
20130143953 | Compositions, kits and methods for treatment of complement-related disorders - Methods, compositions and kits for regulating complement activity or treating a complement activity disorder in a subject using soluble, membrane-independent CD59 protein, methods of assaying human macular degeneration (MD), and methods and kits for assaying potential therapeutic agents for treatment of human MD are provided herein. | 06-06-2013 |
20130149373 | Compositions, methods and kits for modeling, diagnosing, and treating complement disorders - Systems, compositions, methods, and kits for identifying potential therapeutic agents for treatment of complement based ocular diseases are provided herein. The methods and kits include a complement component 3 (C3) protein or derivative that is contacted to ocular cells or tissue. Another embodiment of the invention herein provides for diagnosis and/or prognosis of a complement-associated ocular disease. Compositions, methods and kits for regulating or treating a complement-related condition using at least one of CD46 protein, CD55 protein, and a recombinant chimeric soluble terminator of activated complement (STAC) protein or source of the STAC protein. The STAC protein includes an amino acid sequence including at least two of an amino acid sequence of a CD59 protein, an amino acid sequence derived from a CD46 protein, and an amino acid sequence derived from a CD55 protein, optionally further comprising a linker to connect amino acid sequences. | 06-13-2013 |
Patent application number | Description | Published |
20120253837 | MEDICAL KIOSK AND METHOD OF USE - A medical kiosk having a modular configuration and designed to provide tele-med services to a user. The medical kiosk includes first and second front panels, first and second rear panels, an interior chamber, a chamber access opening, and a user video conferencing system in the interior chamber. The user video conferencing system is designed to enable the user in the interior chamber to have a real-time or near real-time tele-conference with a medical provider located remotely from the medical kiosk. | 10-04-2012 |
20130173287 | MEDICAL KIOSK AND METHOD OF USE - A medical kiosk designed to provide tele-med services, check-in services, and/or prescription services for a user. The medical kiosk can include a user video conferencing system that is designed to enable the user to have a real-time or near real-time tele-conference with a medical provider located remotely from the medical kiosk. | 07-04-2013 |
20140052463 | VETERINARY KIOSK WITH INTEGRATED VETERINARY MEDICAL DEVICES - A veterinary kiosk designed to provide tele-med services, check-in services, and/or prescription services for a user and an animal. The veterinary kiosk can include a user video conferencing system that is designed to enable the user to have a real-time or near real-time tele-conference with a veterinary provider located remotely from the veterinary kiosk. A method of providing veterinary services via a modular veterinary kiosk with one or more integrated veterinary medical devices. | 02-20-2014 |
20140330579 | Medical Kiosk and Method of Use - A medical kiosk designed to provide tele-medicine services, check-in services, and/or prescription services for a user. The medical kiosk can include a user video conferencing system that is designed to enable the user to have a real-time or near real-time tele-conference with a medical provider located remotely from the medical kiosk. | 11-06-2014 |
20150199783 | Medical Kiosk and Method of Use - A medical kiosk designed to provide tele-med services, check-in services, and/or prescription services for a user. The medical kiosk can include a user video conferencing system that is designed to enable the user to have a real-time or near real-time tele-conference with a medical provider located remotely from the medical kiosk. | 07-16-2015 |