Patent application number | Description | Published |
20110045533 | PRODUCTION OF GLYCOSYLATED POLYPEPTIDES IN MICRO ALGAE - Transformed microalgae capable of expressing glycosylated polypeptides and methods for producing said transformed microalgae and producing glycosylated polypeptides. | 02-24-2011 |
20130244265 | SECRETION OF RECOMBINANT POLYPEPTIDES IN THE EXTRACELLULAR MEDIUM OF DIATOMS - A transformed diatom includes a nucleic acid sequence operatively linked to a promoter, wherein the nucleic acid sequence encodes an amino acid sequence including (i) an heterologous signal peptide and (ii) a polypeptide, the heterologous signal peptide leading to the secretion of the polypeptide in the extracellular medium of the transformed diatom; a method for producing a polypeptide which is secreted in the extracellular medium, the method including the steps of (i) culturing a transformed diatom, (ii) harvesting the extracellular medium of the culture and (iii) purifying the secreted polypeptide in the extracellular medium; and use of the transformed diatom for the secretion of a polypeptide in the extracellular medium. | 09-19-2013 |
20140066606 | PRODUCTION OF HIGH MANNOSE GLYCOSYLATED PROTEINS STORED IN THE PLASTID OF MICROALGAE - The present invention concerns a transformed microalga producing a protein harboring a “high mannose” pattern of glycosylation in the plastid of the transformed microalga, wherein 1) the transformed microalga has a Chloroplast Endoplasmic Reticulum (CER); 2) the microalga has been transformed with a nucleic acid sequence operatively linked to a promoter, the nucleic acid sequence encoding an amino acid sequence including (i) an amino-terminal bipartite topogenic signal (BTS) sequence composed of at least a signal peptide followed by a transit peptide; and (ii) The sequence of the protein, 3) the xylosyltransferases and fucosyltransferases of the microalga have not been inactivated; 4) the N-acetylglycosyltransferase I of the microalga has not been inactivated, preferably the N-acetylglycosyltranferases II, III, IV, V and VI, mannosidase II and glycosyltransferases of the microalga have not been inactivated. | 03-06-2014 |
20140154707 | N-GLYCOSYLATION IN TRANSFORMED PHAEODACTYLUM TRICORNUTUM - Transformed | 06-05-2014 |
20150112045 | PRODUCTION OF SECRETED THERAPEUTIC ANTIBODIES IN MICROALGAE - Disclosed is a transformed microalga including a nucleic acid sequence operatively linked to a promoter, wherein the nucleic acid sequence encodes an amino acid sequence including (i) an heterologous signal peptide; and (ii) a therapeutic antibody, a functional fragment or a derivative thereof, the transformed microalga expressing the therapeutic antibody, functional fragment or derivative thereof secreted in the extracellular media and the microalga being selected among green algae except Volvocales, and among red algae, chromalveolates, and euglenids. Preferably, therapeutic antibody, functional fragment or derivative thereof has an increased antibody-dependant cell-mediated cytotoxicity (ADCC) and a low fucose content. The present invention also relates to a method for producing therapeutic antibody, a functional fragment or a derivative thereof, a functional fragment or a derivative thereof in the extracellular medium, to a therapeutic antibody, a functional fragment or a derivative thereof produced and secreted in the extracellular medium of microalgae. | 04-23-2015 |
Patent application number | Description | Published |
20090089116 | Method and System for Acquiring and Tracking Redeemable Codes - Improved approaches to generate, distribute, redeem or return codes are disclosed. The codes can be used (i.e., redeemed) to purchase products from an online store. The codes can be electronically requested and received. In one embodiment, the codes can be acquired from a server via a network. The codes can be content specific codes that are redeemable for particular content, such as specific digital media assets. The codes can be returnable, and royalty obligations that may be due can be adjusted for returns. | 04-02-2009 |
20090089117 | Store Affiliation System - Techniques for improved interaction between online retailers and traditional brick-and-mortar retailers that provide patron-accessible networks are disclosed. The location and/or the fact that any given purchase was made from a particular retailer's patron-accessible network can be tracked for various purposes. The invention can facilitate partnering between online retailers (i.e., online stores) and traditional ‘brick-and-mortar’ business establishments. As an example, the invention can be used to track and give credit for online purchases at an online retailer that are facilitated by a brick-and-mortar retailer. | 04-02-2009 |
20120130840 | STORE AFFILIATION SYSTEM - Techniques for improved interaction between online retailers and traditional brick-and-mortar retailers that provide patron-accessible networks are disclosed. The location and/or the fact that any given purchase was made from a particular retailer's patron-accessible network can be tracked for various purposes. The invention can facilitate partnering between online retailers (i.e., online stores) and traditional ‘brick-and-mortar’ business establishments. As an example, the invention can be used to track and give credit for online purchases at an online retailer that are facilitated by a brick-and-mortar retailer. | 05-24-2012 |
Patent application number | Description | Published |
20090068242 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) - The present invention includes insecticidal carbamates that are useful, for example, for the control of insects, such as mosquitoes, which can be used in applications where exposure to and/or contact with humans is likely. The insecticides of the present invention include phenyl N-methyl carbamates and compositions comprising them that exhibit species-selective inhibition of acetylcholinesterase (AChE) and are preferably toxic to mosquitoes but not humans. Of particular interest are compounds of Formula (I) and Formula (II): | 03-12-2009 |
20120122970 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) - The present invention includes insecticidal carbamates that are useful, for example, for the control of insects, such as mosquitoes, which can be used in applications where exposure to and/or contact with humans is likely. The insecticides of the present invention include phenyl N-methyl carbamates and compositions comprising them that exhibit species-selective inhibition of acetylcholinesterase (AChE) and are preferably toxic to mosquitoes but not humans. Of particular interest are compounds of Formula (I) and Formula (II): | 05-17-2012 |
20160024044 | INHIBITING NEUROTRANSMITTER REUPTAKE - This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine, serotonin, epinephrine or norepinephrine are provided as therapeutic agents for the treatment of depression or anxiety in a mammalian subject. | 01-28-2016 |
Patent application number | Description | Published |
20080200556 | Amine Compounds And Inhibiting Neurotrasmitter Reuptake - The invention relates to amine compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, the invention provides amine compounds, methods for synthesizing amine compounds, and methods for inhibiting neurotransmitter reuptake. | 08-21-2008 |
20080275272 | AMINE COMPOUNDS AND INHIBITING NEUROTRANSMITTER REUPTAKE - The invention relates to amine compounds as well as methods and materials involved in modulating neurotransmitter reuptake. Specifically, the invention provides amine compounds, methods for synthesizing amine compounds, and methods for inhibiting neurotransmitter reuptake. | 11-06-2008 |
20100168246 | AMINE COMPOUNDS AND INHIBITING NEUROTRANSMITTER REUPTAKE - The invention relates to amine compounds as well as methods and materials involved in modulating neurotransmitter reuptake. Specifically, the invention provides amine compounds, methods for synthesizing amine compounds, and methods for inhibiting neurotransmitter reuptake. | 07-01-2010 |
Patent application number | Description | Published |
20100325830 | COATING FOR ELASTOMERIC LINEAR PROFILES, IN PARTICULAR WINDSCREEN-WIPER BLADES, AND PROCESS FOR PRODUCTION THEREOF - The present invention relates to a coating for elastomeric linear profiles, where the coating comprises solid lubricant embedded into a polymeric matrix. It also relates to a wiper blade for windscreen wipers, comprising this type of coating, and also to a process for the production of an elastomeric linear profile coated according to the invention. The polymeric matrix with embedded solid lubricant is obtained by polymerizing, in the absence of polymeric binders, a mixture comprising the solid lubricant and low-molecular-weight crosslinking agent. In one embodiment, the matrix is obtained from the thermal polymerization of the low-molecular-weight crosslinking agent hexamethoxymethylmelamine. Examples of solid lubricants are graphite and HDPE. | 12-30-2010 |
20110059301 | WIPING RUBBER FOR WIPER BLADES IN WINDSHIELD WIPERS - The invention relates to a wiping rubber for wiper blades in windshield wipers, comprising a profile body formed of an elastomer or rubber material, at least partially having a surface coating. The surface coating ( | 03-10-2011 |
20160002452 | WIPER BLADE ELEMENT - The invention relates to a wiper blade element ( | 01-07-2016 |
20160002459 | WIPER BLADE ELEMENT - The invention relates to a wiper blade element ( | 01-07-2016 |