Calvo, US
Angel S. Calvo, Redmond, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20110125660 | System and method for assessment of physical entity attribute effects on physical environments through in part social networking service input - A method includes, but is not limited to: obtaining status information about one or more physical attributes associated with one or more physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, obtaining input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and determining assessment information for at least one of the one or more physical entities based at least in part upon the status information and based at least in part upon the input information. In addition to the foregoing, other related system/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 05-26-2011 |
| 20110125688 | System and method for output of assessment of physical entity attribute effects on physical environments through in part social networking service input - A system includes, but is not limited to: one or more obtaining assessment information modules configured for obtaining assessment information for at least one of one or more physical entities, the assessment information based at least in part upon status information about one or more physical attributes associated with the one or more physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, and the assessment information based at least in part upon input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and one or more output information modules configured for outputting output information based at least in part upon one or more elements of the assessment information. In addition to the foregoing, other related system/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 05-26-2011 |
| 20110125840 | System and method for assessment of physical entity attribute effects on physical environments through in part social networking service input - A system includes, but is not limited to: one or more obtaining status modules configured for obtaining status information about one or more physical attributes associated with one or more physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, one or more obtaining input modules configured for obtaining input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and one or more determining assessment modules configured for determining assessment information for at least one of the one or more physical entities based at least in part upon the status information and based at least in part upon the input information. In addition to the foregoing, other related system/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 05-26-2011 |
| 20110125841 | System and method for comparison of physical entity attribute effects on physical environments through in part social networking service input - A method includes, but is not limited to: obtaining status information about one or more physical attributes associated with one or more first physical entities and one or more second physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, obtaining input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and determining assessment information comparing the one or more first physical entities with the one or more second physical entities based at least in part upon the status information and based at least in part upon the input information. In addition to the foregoing, other related method/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 05-26-2011 |
| 20110125842 | System and method for comparison of physical entity attribute effects on physical environments through in part social networking service input - A system includes, but is not limited to: one or more obtaining status modules configured for obtaining status information about one or more physical attributes associated with one or more first physical entities and one or more second physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, one or more obtaining input modules configured for obtaining input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and one or more determining assessment modules configured for determining assessment information comparing the one or more first physical entities with the one or more second physical entities based at least in part upon the status information and based at least in part upon the input information. In addition to the foregoing, other related system/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 05-26-2011 |
Angel S. Calvo, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100332262 | CLOUD COMPUTING RESOURCE BROKER - Embodiments for interacting with cloud computing providers are disclosed. In accordance with at least one embodiment, a resource broker receives a request for a computing task that is to be performed from a customer. The resource broker selects one of the cloud computing providers to perform at least a part of the computing task. In turn, the resource broker may obtain a gain from performance of the at least one part of the computing task by the cloud computing provider. | 12-30-2010 |
Angel Sarmento Calvo, Seattle, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20150052402 | Cloud Deployment Infrastructure Validation Engine - Embodiments of the invention provide a set of validators that can be used to determine whether an installation is operating within desired parameters and is in compliance with any requirements. The validators may be provided with a software application or release, for example, and may be run during and/or after installation to test the application operation. A set of self-healing operations may be triggered when faults are detected by the validators. This allows a software application to auto-diagnose and auto-self-heal any detected faults. | 02-19-2015 |
| 20150067063 | System and Method for Comparison of Physical Entity Attribute Effects on Physical Environments Through In Part Social Networking Service Input - A method includes, but is not limited to: obtaining status information about one or more physical attributes associated with one or more first physical entities and one or more second physical entities, the one or more physical attributes each being perceived by one or more humans as being capable of having one or more effects upon one or more physical environments, obtaining input information from at least one of the one or more humans through at least in part one or more social networking services, the input information associated with at least one of the one or more physical attributes, and determining assessment information comparing the one or more first physical entities with the one or more second physical entities based at least in part upon the status information and based at least in part upon the input information. In addition to the foregoing, other related method/system aspects are described in the claims, drawings, and text forming a part of the present disclosure. | 03-05-2015 |
Carlos Calvo, Framingham, MA US
| Patent application number | Description | Published |
|---|---|---|
| 20110279192 | APPARATUS AND METHOD FOR DETECTING RADIO FREQUENCY POWER - Apparatus and methods are disclosed related to radio frequency (RF) power detection. One such apparatus includes a directional coupler, an RF switch, and an RF power detector. The RF switch can selectively change coupling between the directional coupler and the RF power detector. This can enable accurate power detection based on a ratio of power levels, without factory calibration or laser trimming. | 11-17-2011 |
Carmela Calvo, Moorestown, NJ US
| Patent application number | Description | Published |
|---|---|---|
| 20110301420 | Trauma Retractor - A trauma retractor optionally including deflation means and an enclosed pressurized vessel capable of being shaped as a torus. When the vessel is shaped as a torus and deflated, the vessel become rigid and one or more holes of the torus may enlarge or remain fixed in size. | 12-08-2011 |
Daivd C. Calvo, Alexandria, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20160125870 | ACOUSTIC FRESNEL ZONE PLATE LENS FOR AQUEOUS ENVIRONMENTS AND METHODS OF USING SAME - An apparatus in a surrounding liquid and methods of using same. The apparatus includes an acoustic Fresnel zone plate comprising a compliant frame, a substrate connected to the frame, and an acoustic diffraction grating connected to the substrate. The acoustic diffraction grating includes a plurality of concentric rings or a plurality of concentric islands. The substrate is acoustic-impedance-mismatched with the acoustic diffraction grating. The acoustic Fresnel zone plate includes at least one acoustic focal spot. The substrate is acoustic-impedance-mismatched with the surrounding liquid and the acoustic diffraction grating is acoustic-impedance-matched with the surrounding liquid, or the substrate is acoustic-impedance-matched with the surrounding liquid and the acoustic diffraction grating is acoustic-impedance-mismatched with the surrounding liquid. | 05-05-2016 |
David C. Calvo, Alexandria, VA US
| Patent application number | Description | Published |
|---|---|---|
| 20120180552 | UNDERSEA PIPELINE INTRUSION DETECTION SYSTEM USING LOW-FREQUENCY GUIDED ACOUSTIC WAVES AND DISTRIBUTED OPTICAL FIBER - A method and an apparatus for intrusion detection. The apparatus includes an acoustic source, a laser light source, a pressure-sensitive optical fiber including a first end and a second end. The second end is connected to the laser light source and oriented toward the acoustic source. The laser light source generates a laser pulse traveling through the pressure-sensitive optical fiber toward the acoustic source. The laser pulse includes a time-of-flight. The acoustic source generates an acoustic wave. The acoustic wave includes a plurality of evanescent wave fronts. The plurality of evanescent wave fronts, upon scattering from a non-uniform material region, radially contracts the pressure-sensitive optical fiber to alter the time-of-flight of the laser pulse along the pressure-sensitive optical fiber by increasing the fiber length. | 07-19-2012 |
Eric Calvo, Bethesda, MD US
| Patent application number | Description | Published |
|---|---|---|
| 20110189120 | AEGYPTIN AND USES THEREOF - The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. | 08-04-2011 |
| 20130123349 | AEGYPTIN AND USES THEREOF - The present invention relates to the discovery of the Aegyptin gene and Aegyptin protein, a molecule that interacts with collagen and inhibits platelet adhesion, activation and aggregation. Novel biological tools, prophylactics, therapeutics, diagnostics, and methods of use of the foregoing are also disclosed. | 05-16-2013 |
Ignacio J. Calvo, Miami, FL US
| Patent application number | Description | Published |
|---|---|---|
| 20080208206 | Surgical tongs - A modified surgical tongs for providing a surgical doctor with a tongs that will permit optimal fixation of the malleous to the tibia, of the olecranon, or of transverse fractures of the patella. The tongs comprises of a pair of hinged legs. Each hinged leg has a first and a second end, the first end of each hinged leg having a handle and the second end having at least one hook. The first hinged leg's perpendicular hook points approximately perpendicular to the plane of the handles. The second hinged leg's parallel hook points toward the perpendicular hook and is in a plane that is approximately parallel to the plane of the handles. Each hinged leg further defines an arcuate locking mechanism that is adjacent to each handle, and each arcuate locking mechanism is in the same plane as each handle. | 08-28-2008 |
Janet Ellis Calvo, Altadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120018457 | Caulking Gun - A dispensing tool for dispensing material from a cartridge includes a cartridge holder defining an opening sized to receive the cartridge and including a cartridge rail. The tool further includes a plunger coupled to the cartridge holder such that it is movable axially through the cartridge holder opening, a plunger restraining member coupled to the cartridge holder, a handle coupled to the cartridge rail, and a trigger pivotably coupled to the handle. The handle may be repositionable along the cartridge rail and the plunger restraining member may disengage with the plunger to allow axial movement when the trigger is pivoted relative to the handle. | 01-26-2012 |
Louis Calvo, Bayshore, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20090044727 | Epoxy additive composition for cement grouts - This invention provides a kit for producing an epoxy additive useful in making a water-soluble grout, which kit comprises, in separate compartments, (a) an epoxy resin selected from the group consisting of (i) a liquid bisphenol A-type epoxy resin, (ii) a liquid bisphenol F-type epoxy resin, (iii) a liquid epoxy phenol novolacs resin, and (iv) an admixture of two or more of any of (i)-(iii); and (b) a composition comprising an admixture of (i) an amine hardener, (ii) a hydrophobic additive and (iii) water; wherein the composition which results from admixing the epoxy resin of part (a) and the composition of part (b) is clear when dried or cured. This invention also provides a related epoxy additive, water-soluble grout and method for producing same. | 02-19-2009 |
Louis M. Calvo, Bayshore, NY US
| Patent application number | Description | Published |
|---|---|---|
| 20100034978 | Compositions for use in construction and methods of applying the same - A composition for use in construction that is substantially free of volatile organic compounds (VOC) that when applied to a surface produces a smooth or textured, water-shedding (hydrophobic properties), aesthetically-pleasing, protective continuous coating. The coated surface as well as the method of preparing and applying the composition is also provided. | 02-11-2010 |
| 20110229727 | LOW VOC MULTICOLOR COATING - A coating composition includes (a) an aqueous polymer emulsion containing a thickener sufficient to provide a viscosity of at least 1,000 at 75 degrees F., and (b) a plurality of particulates suspended in the aqueous polymer emulsion providing special tactile and visual effects such as, for example, multicolor effects, three dimensional effects, metallic sheen and luster, and the like. | 09-22-2011 |
| 20110283917 | COMPOSITIONS FOR USE IN CONSTRUCTION AND METHODS OF APPLYING THE SAME - A composition for use in construction that is substantially free of volatile organic compounds (VOC) that when applied to a surface produces a smooth or textured, water-shedding (hydrophobic properties), aesthetically-pleasing, protective continuous coating. The coated surface as well as the method of preparing and applying the composition is also provided. | 11-24-2011 |
| 20130137793 | Construction Coating Compositions And Methods Of Applying The Same - A composition for use in construction comprising pigment, dry cement and at least 30% powder polymer is provided. The composition has enhanced color retention and abrasion resistance and when applied to a surface the composition produces a smooth or textured, water-shedding properties that are aesthetically-pleasing. The coated surface as well as the method of preparing and applying the composition is also provided. | 05-30-2013 |
Lynn Calvo, Fayetteville, GA US
| Patent application number | Description | Published |
|---|---|---|
| 20140278575 | Systems And Methods Of Processing Insurance Data Using A Web-Scale Data Fabric - Methods and systems for processing data, such as insurance data, using a Web-Scale Data Fabric (WSDF). According to embodiments, a stream ingestion hardware component can ingest messages related to an actionable event and send data objects to an in-memory data store based on the messages. The in-memory data store can retrieve insurance policy information that may be applicable to the actionable event and store the insurance policy information in cache memory. A search-based application interfaces with the in-memory data store to search for and retrieve data associated with the insurance policy information, from which a user or administrator may process or otherwise access the information. The systems and methods can further initiate insurance claim processing as well as enrich the data using various techniques to enable real-time search. | 09-18-2014 |
| 20140280457 | IMPLEMENTATION OF A WEB-SCALE DATA FABRIC - Methods and systems for processing business operations transactions and associated augmented customer data using a Web-Scale Data Fabric (WSDF). According to embodiments, a plurality of computer servers are configured for economical large scale computation and data storage with resilience despite underpinning commodity hardware failure and grow-shrink capacity changes of nodes and associated interconnectivity. The servers communicate with direct attached storage (DAS) and include a co-processor coupled for computation capacity. The servers can connect to an external computer network (ECN) for external client input and output, as well as other functionalities such as physical-to-virtual network connectivity mapping and maintaining resilient storage of data received from the ECN or computationally derived from the received data. | 09-18-2014 |
Mario A. Calvo, Minneapolis, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20130248024 | ELECTROACTIVE POLYMER BASED PRESSURE SENSOR - A sensor including a buffer material layer configured to at least partially deflect when a force or pressure is imparted on the buffer material layer; and an electroactive polymer (EAP) cartridge in operative contact with the buffer material layer, wherein the EAP cartridge is configured to generate an output signal that corresponds to an amount of strain imparted on the EAP cartridge. The EAP cartridge may be used in a variety of sensing applications including as a pressure sensor integrated into a fluid connector. One aspect of the invention provides for selection of a buffer material layer based upon a desired pressure range. | 09-26-2013 |
| 20150107366 | Electroactive Polymer Based Pressure Sensor - A sensor including a buffer material layer configured to at least partially deflect when a force or pressure is imparted on the buffer material layer; and an electroactive polymer (EAP) cartridge in operative contact with the buffer material layer, wherein the EAP cartridge is configured to generate an output signal that corresponds to an amount of strain imparted on the EAP cartridge. The EAP cartridge may be used in a variety of sensing applications including as a pressure sensor integrated into a fluid connector. One aspect of the invention provides for selection of a buffer material layer based upon a desired pressure range. | 04-23-2015 |
Mario A. Calvo, Minneapois, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20110176940 | HIGH PRESSURE INTENSIFIER SYSTEM - A hydraulic pressure intensifier system ( | 07-21-2011 |
Martin Calvo, Chula Vista, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080237239 | Reclosable storage bag having flexible sidewalls combined with less flexible container - A storage system comprising: an evacuable and reclosable bag comprising a wall made of a flexible material and a one-way valve attached to said wall of said bag; a container having walls made of a material less flexible than the flexible material; and an attachment device that attaches the bag to the container such that at least a portion of the bag resides within the container. To use this storage system, compressible articles are placed inside the evacuable bag. Then the bag is hermetically sealed and evacuated. During evacuation, the shape of the compressible articles inside the bag conform to the shape of the container interior volume. In one embodiment, when the bag with compressed articles is removed from the container, its shape facilitates stacking. In another embodiment, the storage bag with compressed articles remains inside the container. | 10-02-2008 |
| 20090052808 | Resealable and evacuable hanging bag with removable hanging device - A hanging storage system comprising a resealable evacuable bag and a hanging device attached to the bag. The hanging device is designed to attach to a portion of the bag in a manner such that a vacuum inside the evacuated bag can be maintained while the bag is hanging, e.g., in a closet. More specifically, the hanging device comprises first and second parts that couple together, the first part being disposed inside the bag and the second part being disposed outside the bag, with a portion of a thin flexible bag wall being disposed between the coupled first and second parts. | 02-26-2009 |
| 20090080809 | Tote bag with inner resealable evacuable flexible bag - A system comprising: a tote bag comprising a container having an opening and means for closing the opening, wherein the container comprises first and second rigid or semi-rigid side walls and a connecting wall made of flexible fabric material; and a resealable evacuable bag placed inside and freely removable from the tote bag via the opening. The resealable evacuable bag comprises: a receptacle having an interior volume and a mouth that allows communication between an exterior and the interior volume, the receptacle comprising flexible front and rear walls and a flexible gusseted bottom; a resealable closure installed in the mouth; a one-way valve mounted to a hole in the front wall; and a rigid or semi-rigid board loosely disposed inside and freely removable from the receptacle and in contact with the gusseted bottom. | 03-26-2009 |
| 20090190863 | PUSH-DOWN COMPRESSIBLE POUCH WITH ONE-WAY VALVES ON SIDES - Airtight compressible storage containers (e.g., pouches) having one-way valves in the form of respective collapsible channels that run along and adjacent to respective pouch side seals. Each collapsible channel comprises unsealed sections of web material that span the space between a respective side seal and a respective interior seal. Each collapsible channel communicates with a respective air inlet located in the interior volume of the pouch and a respective air outlet located on a periphery of the pouch. When the contents of the pouch are compressed by a user pushing down on pouch, air from the storage chamber containing the compressible contents can be forced into the air inlet, through the open channel and out the air outlet until the desired amount of air has been removed from the pouch. | 07-30-2009 |
| 20090190864 | AIRTIGHT EVACUABLE STORAGE BAG AND RELATED METHOD OF MANUFACTURE - Methods for manufacturing airtight storage containers (e.g., bags or pouches) made from thermoplastic web material and having heat-sealed margins along a perimeter. To ensure that the storage containers are airtight, an unheated rib is pressed along each heat seal while the web material in the region of each heat seal is still in a softened and pliable state. As a result of the pressure applied, the rib deforms the contacted portion of the heat-sealed web material, leaving an indentation upon cooling of the web material that serves as an air leakage barrier. This air leakage barrier ensures that any air leakage pathway across the heat seal region is closed. | 07-30-2009 |
| 20090257688 | ONE-WAY VALVE WITH FLAPPER FOR VACUUM BAG - A one-way valve allows air to be drawn from a collapsible, flexible, airtight bag using a vacuum source. When the vacuum source is removed, the one-way valve prevents air from re-entering the bag. The valve assembly comprises a valve base attached to a bag wall and having an opening, a cap base coupled to the valve base, a flapper held in place by the valve base and cap base, and a cap connected to the cap base by a living hinge. When the cap is snapped onto the cap base after bag evacuation, the cap maintains the flapper in a position so that the opening in the valve base stays closed, preventing the admission of ambient air into the evacuated bag. | 10-15-2009 |
Oscar Calvo, Duval, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20100269096 | CREATION, GENERATION, DISTRIBUTION AND APPLICATION OF SELF-CONTAINED MODIFICATIONS TO SOURCE CODE - Systems for creating, generating, distributing and applying self-contained modifications (i.e., changes) to source code are described herein. At least some embodiments include a system including a client computer with processing logic, a storage device (including source code files), and a communication interface. The interface receives a container file including a transformation including a search pattern that identifies source code segments, and transformation instructions that modify the source code based at least partially on identified code segments. Processing logic software searches a representation of the source code for search pattern occurrences, and identifies the source code segments that include elements with structure and relationships that are matched by the corresponding elements represented by the search pattern. The software further modifies at least part of the source code representation according to the transformation instructions, and saves onto the storage device source code files reflecting the application of the transformation. | 10-21-2010 |
Rafael Adolfo Calvo, Altadena, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20120018457 | Caulking Gun - A dispensing tool for dispensing material from a cartridge includes a cartridge holder defining an opening sized to receive the cartridge and including a cartridge rail. The tool further includes a plunger coupled to the cartridge holder such that it is movable axially through the cartridge holder opening, a plunger restraining member coupled to the cartridge holder, a handle coupled to the cartridge rail, and a trigger pivotably coupled to the handle. The handle may be repositionable along the cartridge rail and the plunger restraining member may disengage with the plunger to allow axial movement when the trigger is pivoted relative to the handle. | 01-26-2012 |
Ramiro Calvo, Palo Alto, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20130031462 | WEB APPLICATION ARCHITECTURE - A web application architecture can use a wrapper application to provide a virtual machine environment within a web browser and web applications can run on the wrapper application. The wrapper application can provide life cycle management for the web applications and provide other functions such as log in and log out for all of the web applications in the environment. | 01-31-2013 |
Ramiro Calvo, Cupertino, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20160062584 | ANCHORING VIEWPORT - The present disclosure relates to techniques of configuring a layout of graphical objects for display. In one example process, the device detects a scroll request and determines whether the scroll request meets predetermined criteria. If the scroll request meets the criteria, the device configures the layout of graphical objects that are to be displayed once the display is scrolled so that the graphical objects are arranged on the display differently than the arrangement in which the graphical objects would have been displayed, had the layout not been configured. If the scroll request does not meet the criteria, the device forgoes the configuration of the layout of graphical objects. | 03-03-2016 |
Raul Calvo, Royersford, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20110218197 | SUBSTITUTED AZA-BICYCLIC IMIDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS - The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. | 09-08-2011 |
| 20120202856 | SUBSTITUTED BENZIMDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS - The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. | 08-09-2012 |
| 20140155395 | SUBSTITUTED AZA-BICYCLIC IMIDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS - The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. | 06-05-2014 |
| 20150158875 | SUBSTITUTED AZA-BICYCLIC IMIDAZOLE DERIVATIVES USEFUL AS TRPM8 RECEPTOR MODULATORS - The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold. | 06-11-2015 |
Raul R. Calvo, Royersford, PA US
| Patent application number | Description | Published |
|---|---|---|
| 20100292276 | BENZIMIDAZOLE DERIVATIVES USEFUL AS TRP M8 RECEPTOR MODULATORS - The present invention is directed to benzimidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8 (transient receptor potential M8 channel). More particularly, the compounds of the present invention are useful in the treatment of inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold, anxiety and depression. | 11-18-2010 |
| 20110190344 | BENZIMIDAZOLE MODULATORS OF VR1 - The invention is directed to compounds of Formula (I): | 08-04-2011 |
| 20110190364 | BENZIMIDAZOLE MODULATORS OF VR1 - The invention is directed to compounds of Formula (I): | 08-04-2011 |