Patent application number | Description | Published |
20080207564 | Derivaitves of 4-Or 5-Aminosalicylic Acid - The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer. | 08-28-2008 |
20090306412 | 4-HYDROXYTHIOBENZAMIDE DERIVATIVES OF DRUGS - Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The compounds of the present invention exhibit enhanced activity or reduced side effects or both. | 12-10-2009 |
20100210607 | HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS - The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatized with a hydrogen sulfide (H | 08-19-2010 |
20110098257 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID - The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer. | 04-28-2011 |
20110130368 | DERIVATIVES OF 4- OR 5-AMINOSALICYLIC ACID - The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention/treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention/treatment of colon cancer. | 06-02-2011 |
20110144188 | SALTS OF TRIMEBUTINE AND N-DESMETHYL TRIMEBUTINE - Unique salts of trimebutine and N-monodesmethyl trimebutine, and their corresponding stereoisomers, having improved analgesic properties useful in the treatment of visceral pain are provided. The salts of the present invention are particularly useful in the treatment of conditions characterized by abdominal pain, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), diabetic gastroparesis, and dyspepsia. | 06-16-2011 |
Patent application number | Description | Published |
20090295258 | Actuator arrangement with worm gear and rotational output - A first embodiment is an actuator arrangement having a rotational output and a motor. The actuator arrangement further includes at least one intermediate gear, an output gear, and an encoding detector. The motor has an output shaft that includes a worm gear. The output gear generates a rotational output at an axis thereof. Position encoding indicia are fixedly arranged on the output gear. The encoding detector is disposed in position to detect the position encoding indicia. | 12-03-2009 |
20140070673 | ACTUATOR ARRANGEMENT WITH WORM GEAR AND ROTATIONAL OUTPUT HAVING AN ENCODER - An actuator arrangement having a rotational output includes a power input, a motor, at least an intermediate gear, a solenoid and an output. The power input connects to a source of electrical power. The motor has an output shaft including a worm gear. The motor is operably connected to the power input. The motor and output shaft are rotatably connected to a housing of the actuator. The output gear generates a rotational output at an axis thereof, and is operably coupled to be driven by the at least one intermediate gear. The solenoid is operably connected to the power input, and includes a piston member. The piston member has an actuated and a non-actuated position. The piston member in the actuated position urges the worm gear and the at least one intermediate gear into meshing connection. | 03-13-2014 |
20140273783 | SASH POSITION DETERMINING SYSTEM - A system for determining a sash panel position. An example system includes a linear array of light emitting elements spaced at equal distances from one another mounted on a fume hood frame. The light emitting elements generate a light path towards a sash panel such that the sash panel blocks the light path when positioned at the light emitting element. A linear array of light sensing elements is spaced at equal distances from one another on a side opposite the sash panel. The light sensing elements receive the light path generated by corresponding light emitting elements when the sash panel does not block the light path. The light sensing elements may be on modules having shift registers with bits corresponding to the light sensing elements. The shift register stores a state of the light sensing element and outputs a series of bits indicating the state of each light sensing element. | 09-18-2014 |
Patent application number | Description | Published |
20090001282 | METHODS AND APPARATUS FOR ASSIGNING A BEAM INTENSITY PROFILE TO A GAS CLUSTER ION BEAM USED TO PROCESS WORKPIECES - Embodiments of the invention describe methods and apparatus for assigning a beam intensity profile to a gas cluster ion beam and processing workpieces using a gas cluster ion beam. One embodiment includes generating a gas cluster ion beam in a gas cluster ion beam processing apparatus, collecting parametric data relating to the spatial intensity of the gas cluster ion beam, and generating a beam intensity profile describing the spatial intensity of the gas cluster ion beam by fitting a mathematical functional shape to the parametric data. Another embodiment describes a method for processing a workpiece using a gas cluster ion beam. | 01-01-2009 |
20090037015 | METHOD AND SYSTEM FOR INCREASING THROUGHPUT DURING LOCATION SPECIFIC PROCESSING OF A PLURALITY OF SUBSTRATES - A method and system of location specific processing on a plurality of substrates is described. The method comprises measuring metrology data for the plurality of substrates. Thereafter, the method comprises computing correction data for a first substrate using the metrology data, followed by computing correction data for a second substrate using the metrology data. While computing the correction data for a second substrate, the method comprises applying the correction data for a first substrate to the first substrate using a gas cluster ion beam (GCIB). | 02-05-2009 |
20090084672 | METHOD AND SYSTEM FOR ADJUSTING BEAM DIMENSION FOR HIGH-GRADIENT LOCATION SPECIFIC PROCESSING - A method and system of location specific processing on a substrate is described. The method comprises establishing a gas cluster ion beam (GCIB) according to a set of beam properties and measuring metrology data for a substrate. Thereafter, the method comprises determining at least one spatial gradient of the metrology data at one or more locations on the substrate and adjusting at least one beam property in the set of beam properties for the GCIB according to the determined at least one spatial gradient. Using the metrology data and the adjusted set of beam properties, correction data for the substrate is computed. Following the computing, the adjusted GCIB is applied to the substrate according to the correction data. | 04-02-2009 |
20090084759 | METHOD AND SYSTEM FOR MULTI-PASS CORRECTION OF SUBSTRATE DEFECTS - A method and system of location specific processing on a substrate is described. The method comprises acquiring metrology data for a substrate, and computing correction data for adjusting a first region of the metrology data on the substrate. Thereafter, a first gas cluster ion beam (GCIB) for treating the high gradient regions is established, and the first GCIB is applied to the substrate according to the correction data. The method further comprises optionally acquiring second metrology data following the applying of the first GCIB, and computing second correction data for adjusting a second region of the metrology data, or the second metrology data, or both on the substrate. Thereafter, a second gas cluster ion beam (GCIB) for treating the second region is established, and the second GCIB is applied to the substrate according to the second correction data. | 04-02-2009 |
20150137006 | MULTI-STEP LOCATION SPECIFIC PROCESS FOR SUBSTRATE EDGE PROFILE CORRECTION FOR GCIB SYSTEM - Disclosed are an apparatus, system, and method for scanning a substrate or other workpiece through a gas-cluster ion beam (GCIB), or any other type of ion beam. The workpiece scanning apparatus is configured to receive and hold a substrate for irradiation by the GCIB and to scan it through the GCIB in two directions using two movements: a reciprocating fast-scan movement, and a slow-scan movement. The slow-scan movement is actuated using a servo motor and a belt drive system, the belt drive system being configured to reduce the failure rate of the workpiece scanning apparatus. | 05-21-2015 |
20150348746 | MULTI-STEP LOCATION SPECIFIC PROCESS FOR SUBSTRATE EDGE PROFILE CORRECTION FOR GCIB SYSTEM - Disclosed are an apparatus, system, and method for scanning a substrate or other workpiece through a gas-cluster ion beam (GCIB), or any other type of ion beam. The workpiece scanning apparatus is configured to receive and hold a substrate for irradiation by the GCIB and to scan it through the GCIB in two directions using two movements: a reciprocating fast-scan movement, and a slow-scan movement. The slow-scan movement is actuated using a servo motor and a belt drive system, the belt drive system being configured to reduce the failure rate of the workpiece scanning apparatus. | 12-03-2015 |