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Buser

Anthony J. Buser, Reading, PA US

Patent application numberDescriptionPublished
20140043630DISPLAYS FOR THREE-DIMENSIONAL PRINTERS - A variety of techniques are disclosed for incorporating displays into three-dimensional printers.02-13-2014

Anthony James Buser, Reading, PA US

Patent application numberDescriptionPublished
20130095302GRAYSCALE RENDERING IN 3D PRINTING - An additive three-dimensional fabrication process uses multiple build materials with different optical properties (e.g., color, opacity) at different surface depths to achieve grayscale-rendered images on exterior surfaces thereof.04-18-2013
20130297320VOICE-CONTROLLED THREE-DIMENSIONAL FABRICATION SYSTEM - An additive three-dimensional fabrication system includes voice control for user interaction. This voice-controlled interface can enable a variety of voice-controlled functions and operations, while supporting interactions specific to consumer-oriented fabrication processes.11-07-2013
20130329243DOWNLOADABLE THREE-DIMENSIONAL MODELS - A server is configured to store a number of different models of an object in machine-ready form corresponding to a number of different three-dimensional printers having differing capabilities and/or hardware configurations. When a user at a client device or a printer requests the object, the server automatically determines a printer type and selects a suitable, corresponding machine-ready model for immediate fabrication by the printer.12-12-2013
20130329257DOWNLOADABLE THREE-DIMENSIONAL MODELS - A server is configured to store a number of different models of an object in machine-ready form corresponding to a number of different three-dimensional printers having differing capabilities and/or hardware configurations. When a user at a client device or a printer requests the object, the server automatically determines a printer type and selects a suitable, corresponding machine-ready model for immediate fabrication by the printer.12-12-2013
20130329258DOWNLOADABLE THREE-DIMENSIONAL MODELS - A server is configured to store a number of different models of an object in machine-ready form corresponding to a number of different three-dimensional printers having differing capabilities and/or hardware configurations. When a user at a client device or a printer requests the object, the server automatically determines a printer type and selects a suitable, corresponding machine-ready model for immediate fabrication by the printer.12-12-2013
20140036034THREE-DIMENSIONAL PRINTER WITH LASER LINE SCANNER - A three-dimensional printer includes a laser line scanner and hardware to rotate the scanner relative to an object on a build platform. In this configuration, three-dimensional surface data can be obtained from the object, e.g., for use as an input to subsequent processing steps such as the generation of tool instructions to fabricate a three-dimensional copy of the object, or various surfaces thereof.02-06-2014
20140036035PRINTER WITH LASER SCANNER AND TOOL-MOUNTED CAMERA - A three-dimensional printer includes a laser line scanner and hardware to rotate the scanner relative to an object on a build platform. In this configuration, three-dimensional surface data can be obtained from the object, e.g., for use as an input to subsequent processing steps such as the generation of tool instructions to fabricate a three-dimensional copy of the object, or various surfaces thereof.02-06-2014
20140043441MOBILE DEVICE ACCESSORY FOR THREE-DIMENSIONAL SCANNING - A variety of techniques are disclosed for enabling three-dimensional scanning with mobile devices. In general, an accessory provides additional optics, image sensors, lighting and/or processing to complement preexisting device hardware in support of a variety of three-dimensional imaging techniques.02-13-2014
20140043442MOBILE DEVICE ACCESSORY FOR THREE-DIMENSIONAL SCANNING - A variety of techniques are disclosed for enabling three-dimensional scanning with mobile devices. In general, an accessory provides additional optics, image sensors, lighting and/or processing to complement preexisting device hardware in support of a variety of three-dimensional imaging techniques.02-13-2014
20140265035THREE-DIMENSIONAL PRINTING WITH CONTROL OF THERMOALTERABLE BUILD MATERIALS - A variety of thermoalterable build materials are disclosed for use in three-dimensional printing, along with techniques for controlling properties of such materials in a fabricated object. In particular, changes in material flow rate permit instantaneous changes in heat transfer and resulting variations in the amount of thermoalteration, without requiring any changes to the temperature of a heater or extruder used to extrude the material. In this manner, flow rate facilitates spatial control of properties within a fabricated object.09-18-2014

Anthony James Buser, Linden, NJ US

Patent application numberDescriptionPublished
20150348557VOICE-CONTROLLED THREE-DIMENSIONAL FABRICATION - An additive three-dimensional fabrication system includes voice control for user interaction. This voice-controlled interface can enable a variety of voice-controlled functions and operations, while supporting interactions specific to consumer-oriented fabrication processes.12-03-2015

Antonius Johannes Wilhelmus Buser, Wehl NL

Patent application numberDescriptionPublished
20130041091CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST - The present invention relates to a crosslinkable composition comprising at least one crosslinkable component crosslinkable by a latent base crosslinking catalyst comprising a substituted carbonate salt according to formula 1 wherein X02-14-2013
20130053505CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST - The present invention relates to a crosslinkable composition comprising at least one crosslinkable component and a latent base crosslinking catalyst, which crosslinkable composition has a solids content of typically at least 55 wt (dry weight after crosslinking relative to the total weight of the crosslinking composition) wherein the latent base catalyst is a substituted carbonate salt according to formula (I) wherein X02-28-2013
20130210986CROSSLINKABLE COMPOSITION CROSSLINKABLE WITH A LATENT BASE CATALYST - The present invention relates to a crosslinkable composition comprising at least one crosslinkable component and a latent base crosslinking catalyst, which crosslinkable composition has a solids content of typically at least 55 wt (dry weight after crosslinking relative to the total weight of the crosslinking composition) wherein the latent base catalyst is a substituted carbonate salt according to formula (I) wherein X08-15-2013
20140220252CROSSLINKABLE COMPOSITION COMPRISING A LATENT BASE CATALYST AND LATENT BASE CATALYST COMPOSITIONS - A crosslinkable composition including at least one crosslinkable component that is crosslinkable under the action of a base catalyst, a first carbonate salt according to a first formula as latent base crosslinking catalyst, and a second carbonate salt according to a second formula as potlife extender, wherein the second carbonate is present in an amount of at least 5 mole % and preferably at most 500 mole % relative to the molar amount of the first carbonate. Further disclosed are catalyst compositions composed of the first and second carbonate salts, to the use of the catalyst composition as base catalyst system in crosslinkable compositions and the crosslinkable compositions, in particular coating compositions comprising the catalyst composition.08-07-2014
20140221542CROSSLINKABLE COMPOSITION CROSS-LINKABLE BY REAL MICHAEL ADDITION REACTION AND RESINS FOR USE IN SAID COMPOSITION - An RMA crosslinkable composition having at least one crosslinkable component including reactive components A and B each including at least 2 reactive groups, the at least 2 reactive groups of component A being acidic protons (C—H) in activated methylene or methine groups and the at least 2 reactive groups of component B are activated unsaturated groups (C═C) and a base catalyst (C) which reactive components A and B crosslink by Real Michael Addition (RMA) reaction under action of the base catalyst, characterised in that the at least one crosslinkable component including reactive components A and B in the composition have a total hydroxy number of less than 60, preferably less than 40 and more preferably less than 20 mg KOH/g solids. Further, specific resins A and B having a low hydroxy number for use in RMA cross-linkable compositions and a process for the manufacture thereof.08-07-2014
20140235785CROSSLINKABLE COMPOSITION CROSSLINKABLE BY REAL MICHAEL ADDITION (RMA) REACTION - A crosslinkable composition including a component A with at least 2 acidic protons C—H in activated methylene or methine groups (the RMA donor group), and a component B with at least 2 activated unsaturated groups (the RMA acceptor group), and a catalyst system C that contains, or is able to generate a basic catalyst capable of activating the RMA reaction between components A and B, characterised in that the cross-linkable composition further includes an X—H group containing component D that is also a Michael addition donor reactable with component B under the action of catalyst C, wherein X is N, P, O, S or wherein X is C as part of an acidic methyl (CH3) group. A component D and catalyst additive mixtures for the manufacture of RMA crosslinkable composition.08-21-2014
20160060482CROSSLINKABLE COMPOSITION - An RMA crosslinkable composition for making thick coating layers having at least one crosslinkable component comprising reactive components A and B each including at least 2 reactive groups wherein the at least 2 reactive groups of component A are acidic protons (C—H) in activated methylene or methine groups, and the at least 2 reactive groups of component B are activated unsaturated groups (C═C), to achieve crosslinking by Real Michael Addition reaction, the composition further including a base catalyst (C), an X—H group containing component (D) that is also a Michael addition donor reactable with component B under the action of catalyst C, wherein X is C, N, P, O or S and a sag control component (E). A crosslinkable composition is also disclosed for preparing thick coating layers having a dry thickness of at least 70 mu having a surface appearance and hardness of the resulting cured composition.03-03-2016

Patent applications by Antonius Johannes Wilhelmus Buser, Wehl NL

Cimarron Buser, Wellesely Hills, MA US

Patent application numberDescriptionPublished
20120284704PROCESSING, MODIFICATION, DISTRIBUTION OF INSTALLATION PACKAGES - According to example configurations, a customization engine receives a default installation package. The installation package supports installation of a respective application to a computing device. The customization engine further receives a set of rules indicating at least one alteration to be applied to the received installation package to transform the received installation package into a customized installation package. The customization engine further receives a set of data to be applied according to the rules. The customization engine modifies the received default installation package in accordance with the set of rules and supplied data to produce the customized installation package.11-08-2012

Claudia Buser, Bridgewater, NJ US

Patent application numberDescriptionPublished
20160100570ULTRA-HIGH DENSITY CELL BANKING METHODS - Provided are methods for the creation of ultra-high density cryopreserved cell banks. In certain embodiments, these methods employ altered perfusion culture techniques that allow for production of ultra-high density cell cultures that can be cryopreserved at unexpectedly high cell densities without the need for any cell concentration steps, while retaining excellent cell viability and quality.04-14-2016

Claudia Buser, Framingham, MA US

Patent application numberDescriptionPublished
20140273206HIGH DENSITY CELL BANKING METHODS - The current disclosure provides a method for the creation of a high-density cryopreserved cell bank using perfusion culture techniques and non-centrifugal concentration of cells. Methods of production using this high-density cryopreserved cell bank are also provided.09-18-2014

Dominik Buser, Thurneu CH

Patent application numberDescriptionPublished
20120056628Propagation Time Measuring Method for Determining a Distance - An apparatus for ascertaining and monitoring a fill level and includes a transmitting/receiving unit and a delay circuit. The delay circuit includes at least a sampling clocking oscillator, which produces a sampling signal having a sampling frequency, a transmission clocking oscillator, which produces a pulse repetition signal having a pulse repetition frequency and a frequency converter, which produces by means of sequential sampling a difference signal. The apparatus further includes a control/evaluation unit, which determines on the basis of travel time the fill level. Provided on the control/evaluation unit is an external clocking input, which is connected via a clocking line with a first clocking output of the sampling clocking oscillator or with a second clocking output of the transmission clocking oscillator. A stabilized and cost-favorable control circuit for producing an intermediate frequency signal with a highly accurately determinable, transformation factor results.03-08-2012

Ed Buser, Sunrise, FL US

Patent application numberDescriptionPublished
20140195294Method and System for High Volume Document Processing - A system and method configured for a dynamic sorting scheme is disclosed. The method may comprise receiving a mailing data corresponding to multiple mailing pieces, analyzing the mailing data based on an intended geographic destinations of the multiple mailing pieces and determining multiple geographic location groupings, filtering the mailing data into the multiple geographic location groupings, selecting a number of product type groupings based on product information of the multiple mailing pieces, electronically sorting the multiple mailing pieces based on mail qualifier criteria, determining a processing schedule of available sorting equipment and personnel for processing the multiple mailing pieces, simulating the processing of the multiple mailing pieces using the processing schedule, adjusting the processing schedule based on a result of the simulating the processing of the multiple mailing pieces, and sorting the multiple mailing pieces into multiple processing jobs.07-10-2014

Franz Buser, Buckten CH

Patent application numberDescriptionPublished
20100314053Blind Slat - A blind slat (12-16-2010

Jack Buser, San Francisco, CA US

Patent application numberDescriptionPublished
20090063277ASSOCIATING INFORMATION WITH A PORTION OF MEDIA CONTENT - A media fingerprint is derived from a portion of media content. Information is associated with the media content portion based on the derived media fingerprint. Upon linking to the associated information, the associated content is presented with the media content portion. The media fingerprint includes a unique representation of the media content portion that is derived from a characteristic component of the media content portion. The media content may comprise an original instance of content or a derivative instance of the original content.03-05-2009
20110022589ASSOCIATING INFORMATION WITH MEDIA CONTENT USING OBJECTS RECOGNIZED THEREIN - At least one object within a portion of media content is recognized. The object is essentially a feature of the media content portion. Information is associated with the recognized object based on recognizing the object.01-27-2011
20120099760ASSOCIATING INFORMATION WITH A PORTION OF MEDIA CONTENT - A media fingerprint is derived from a portion of media content. Information is associated with the media content portion based on the derived media fingerprint. Upon linking to the associated information, the associated content is presented with the media content portion. The media fingerprint includes a unique representation of the media content portion that is derived from a characteristic component of the media content portion. The media content may comprise an original instance of content or a derivative instance of the original content.04-26-2012
20120143679ASSOCIATING INFORMATION WITH A PORTION OF MEDIA CONTENT - A media fingerprint is derived from a portion of media content. Information is associated with the media content portion based on the derived media fingerprint. Upon linking to the associated information, the associated content is presented with the media content portion. The media fingerprint includes a unique representation of the media content portion that is derived from a characteristic component of the media content portion. The media content may comprise an original instance of content or a derivative instance of the original content.06-07-2012

Patent applications by Jack Buser, San Francisco, CA US

John Buser, San Diego, CA US

Patent application numberDescriptionPublished
20090030443SAFETY-STOP TROCHAR DEVICE AND SYSTEM - A safety-stop trochar device and system for use with a trochar and surgical accessory devices. The device and system has a base into which an insert seats over which a cap secures to the base and also secures a previously inserted trochar or drainage device or smoke evacuator or surgical accessory such as an obturator and illumination device. Flexible extension wings on the base have distal suture apertures or an adhesive on the bottom of the base, or both, for securing the base to a patient. U-shaped extensions on the cap facilitate cap placement or removal onto or from the base.01-29-2009
20150059542Dust Capturing Device for Reciprocating Saws - A Dust Capturing Device for Reciprocating Saws is disclosed. The device is attachable to a convenational shop vacuum cleaner so that virtually all dust created by the reciprocating saw at the cutting blade is captured by the vacuum cleaner. The system is universally attachable to all powered reciprocating saws on the market. A pair of suction hoses are snugly attached to the body of the saw, from intake ports located adjacent to the saw blade to an adapter manifold that combines the two suction hoses into a single hose adaptable to the vacuum cleaner hose. The hoses are attached to the body of the saw by one or more body straps, with each body strap having a pair of hose clips extending therefrom for restraining the two suction hoses running along the body.03-05-2015

Patent applications by John Buser, San Diego, CA US

John P. Buser, San Diego, CA US

Patent application numberDescriptionPublished
20100063529SAFETY-STOP DEVICE - A safety-stop device for use with a trochar which is adjustably attachable to the trochar tube to prevent inadvertent cuts being made to a patient. The safety-stop device has retention component for retaining it onto the trochar tube; a registration component for registering a pre-determined insertion point of the trochar; a stop component for preventing additional insertion of the trochar after the pre-determined insertion point has been attained; and a plurality wings with apertures on the base for securely suturing the safety-stop device to a patient by suturing through the apertures and into the patient. The base and wings are made of any thermoplastic material.03-11-2010

Josef A. Buser, Schoenenberg-Kuebelberg DE

Patent application numberDescriptionPublished
20120145193DISHWASHER SYSTEM WITH A REUSE TANK - A method of operating a dishwasher having a wash tub and a reuse tank for storing liquid for subsequent reuse, wherein the condition of the water in the reuse tank may be monitored and/or acted upon to limit the likelihood of undesired effects associated with the growth of micro-organisms in the liquid.06-14-2012
20120145195DISHWASHER SYSTEM WITH A REUSE TANK - A method of operating a dishwasher having a wash tub and a reuse tank for storing liquid for subsequent reuse, wherein the condition of the water in the reuse tank may be monitored and/or acted upon to limit the likelihood of undesired effects associated with the growth of micro-organisms in the liquid.06-14-2012
20160037996DISHWASHER SYSTEM WITH A REUSE TANK - A method of operating a dishwasher having a wash tub and a reuse tank for storing liquid for subsequent reuse, wherein the condition of the water in the reuse tank may be monitored and/or acted upon to limit the likelihood of undesired effects associated with the growth of micro-organisms in the liquid.02-11-2016

Josef Arnold Buser, Schoenenberg-Kuebelberg DE

Patent application numberDescriptionPublished
20100154842STEAM GENERATOR FOR A DISHWASHER - A dishwasher includes a steam-generating vessel positioned in the wash chamber of the dishwasher's tub. A heating element heats water contained in the vessel to generate steam. The heating element may be embodied as thick-film heating element. The steam-generating vessel may be formed in the dishwasher's tub or embodied as a separate component that is secured to the tub.06-24-2010

Joshua Buser, Seattle, WA US

Patent application numberDescriptionPublished
20150203806SYSTEMS FOR DISRUPTING BIOLOGICAL SAMPLES AND ASSOCIATED DEVICES AND METHODS - The present technology relates generally to systems for disrupting biological samples and associated devices and methods. In some embodiments, system includes a vessel configured to receive the biological sample, a permanent magnet configured to be positioned within the vessel, an electromagnet configured to be positioned proximate the vessel, and a current source operably coupled to the electromagnet and configured to transmit an alternating current. In some embodiments, when the biological sample is placed within the vessel and the alternating current is transmitted to the electromagnet, the electromagnet produces an alternating magnetic field that causes the permanent magnet to rotate within the vessel, thereby lysing at least one of the cells of the biological sample.07-23-2015
20150361487SEQUENTIAL DELIVERY OF FLUID VOLUMES AND ASSOCIATED DEVICES, SYSTEMS AND METHODS - The present technology is directed to capillarity-based devices for performing chemical processes and associated system and methods. In one embodiment, for example, a device can include a porous receiving element having an input region and a receiving region, a first fluid source and a second fluid source positioned within the input region of the receiving element; wherein the first fluid source is positioned between the second fluid source and the receiving region, and wherein, when both the first and second fluid sources are in fluid connection with the input region, the device is configured to sequentially deliver the first fluid and the second fluid to the receiving region without leakage.12-17-2015

Mark F. Buser, Jupiter, FL US

Patent application numberDescriptionPublished
20120018366FLUID SEPARATION SYSTEM WITH REDUCED FOULING - A fluid separation system includes a separation membrane having a pattern of features thereon.01-26-2012

Mark L. Buser, Green Brook, NJ US

Patent application numberDescriptionPublished
20120084453ADJUSTING AUDIO AND VIDEO SYNCHRONIZATION OF 3G TDM STREAMS - Systems and methods of adjusting synchronization of audio media streams and video media streams in 3G mobile communications systems that can mitigate the effects of temporal skew due to intervening processing elements associated with media channels carrying the respective media streams. The systems and methods are operative to adjust the synchronization of audio media streams and video media streams by receiving control messages that report delays due to such intervening processing elements, calculating a relative amount of delay using the reported delays for each media channel, and applying a delay factor based on the relative amount of delay to the faster media channel to place the audio media streams and the video media streams in proper temporal alignment. The delay factor is applied to the faster media channel at those locations within the mobile communications systems where the audio and video media streams are combined and/or separated for subsequent transmission.04-05-2012

Martin Buser, Basel CH

Patent application numberDescriptionPublished
20120112658COLOR TEMPERATURE CONTROL OF FLASH UNITS - A flash unit (05-10-2012

Michael Buser, Ottobrunn DE

Patent application numberDescriptionPublished
20090083059SYSTEM AND METHOD FOR RETROACTIVE, DYNAMIC MONITORING OF LOW LAYOUT HEIGHTS IN DANGEROUS EVENTS - The invention relates to a system and to a method for retroactive, dynamic determination and/or monitoring of low layout heights of technical systems (03-26-2009

Rudolf G. Buser, Wall, NJ US

Patent application numberDescriptionPublished
20110037965Combined Coherent and Incoherent Imaging LADAR - The present invention relates generally to a long range eye-safe laser radar (LADAR) system for use in an environment where real-time non-cooperative identification of an object is required. In particular, a laser beam is aimed at an object, the laser energy reflected from the object is collected by a detector array for use in generating a composite of both a high resolution 3-Dimensional (3D) shape of the object and the object's high resolution micro-Doppler vibration spectrum, a characteristic of the object as unique as a fingerprint. The composite is then used to automatically identify the object by comparison to a database of similar composite sets of 3D shape and vibration spectrum information with the results of the identification conveyed to the user.02-17-2011

Stephan Buser, Sursee CH

Patent application numberDescriptionPublished
20120136081Resorbable Polyurethane Wound Cover - The present invention relates to a biocompatible, resorbable polyurethane foam wound cover with open pores and an adjustable resorption rate having improved properties when used on skin or connective tissue wounds as well as a method of production of such a polyurethane foam wound cover.05-31-2012
20130288034Resorbable Membrane - The present invention relates to resorbable membranes for medical uses. The membranes according to the present invention are produced or producible from a composition comprising at least one polyol component, at least one polyisocyanate component and an additive selected from polyvinylpyrrolidone, polyvinylpolypyrrolidone, a copolymer of polyvinylpyrrolidone with vinylacetate, vinylimidazole or vinylcaprolactam or mixtures thereof. The present invention further relates to a kit comprising a multitude of membranes with different absorption rates.10-31-2013
20150247074Method for Producing a Two-Component Polyurethane Composition Comprising One or More Additives Soluble in Polar Solvents - A method for producing a two-component polyurethane composition comprising at least one additive soluble in polar solvents, in particular a biocide, comprising the following steps: a) providing at least one polyol; b) adding at least one solution of the polar solvent comprising at least one additive soluble in polar solvents, in particular a biocide, and at least one carrier material for the additive to the polyol from step a); and c) providing, in accordance with the requirements, at least one isocyanate for adding to the mixture from step b). The method has the advantage that additives can be incorporated into a two-component polyurethane composition without agglomerating or precipitating, without side reactions, and without an additional drying step.09-03-2015

Patent applications by Stephan Buser, Sursee CH

Thomas Buser, Nuglar CH

Patent application numberDescriptionPublished
20110097394TYPE A GELATIN CAPSULE CONTAINING PUFA IN FREE ACID FORM - A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.04-28-2011
20130123362TYPE A GELATIN CAPSULE CONTAINING PUFA IN FREE ACID FORM - A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft to gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.05-16-2013
20140056980DELAYED RELEASE DRUG FORMULATION - In a delayed release formulation comprising a core containing a drug and a delayed release coating for providing intestinal release, release of the drug in the colon is accelerated by including an isolation layer between the core and the delayed release coating. The delayed release coating comprises an inner layer and an outer layer. The outer layer comprises a pH dependently soluble polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a soluble polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said soluble polymeric material being selected from the group consisting of a polycarboxylic acid polymer that is at least partially neutralised, and a non-ionic polymer, provided that, where said soluble polymeric material is a non-ionic polymer, said inner layer comprises at least one additive selected from a buffer agent and a base.02-27-2014
20150125525DELAYED RELEASE DRUG FORMULATION - Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an inner layer and an outer layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said third polymeric material being selected from an at least partially neutralised polycarboxylic acid and a non-ionic polymer. In embodiments in which the third polymeric material is a non-ionic polymer, the inner layer comprises at least one of a buffer agent and a base. Advantages of formulations according to the present invention include accelerated release of the drug when exposed to colonic conditions and reduction or elimination of a food and/or alcohol effect on drug release after administration.05-07-2015
20150132380A DELAYED RELEASE DRUG FORMULATION - Delayed release of a drug to the colon is achieved from a delayed release formulation comprising a core and a coating for the core. The core comprises a drug and the coating comprises an outer layer and at least one layer between the core and the outer layer selected from the group consisting of an isolation layer and an inner layer. The outer layer comprises a mixture of a first polymeric material which is susceptible to attack by colonic bacteria, and a second polymeric material which has a pH threshold at about pH 5 or above. The inner layer comprises a third polymeric material which is soluble in intestinal fluid or gastrointestinal fluid, said third polymeric material being selected from an at least partially neutralised polycarboxylic acid and a non-ionic polymer. In embodiments in which the third polymeric material is a non-ionic polymer, the inner layer comprises at least one of a buffer agent and a base. The isolation layer comprises a non-ionic polymer which is soluble in intestinal fluid or gastrointestinal fluid. The outer is applied directly to the inner layer or the isolation layer using a coating preparation formed by combining the first polymeric material in an aqueous medium with a second polymeric material in an organic medium. Advantages of formulations according to the present invention include accelerated release of the drug when exposed to colonic conditions and reduction or elimination of a food and/or alcohol effect on drug release after administration.05-14-2015
20150238430PHARMACEUTICAL COMPOSITION - A pharmaceutical formulation comprising at least one omega-3 polyunsaturated fatty acid in free acid form or a pharmacologically acceptable derivative thereof is contained in a soft gelatin capsule characterised in that the capsule comprises gelatin extracted by an extraction process comprising acid pre-treatment of a collagen source. One advantage of the present invention over a soft gelatin capsule containing the same formulation but comprising gelatin extracted by an extraction process comprising alkali pre-treatment of the collagen source is that the present invention does not harden significantly over time and thus has a longer shelf life.08-27-2015

Patent applications by Thomas Buser, Nuglar CH

Zorica Buser, San Francisco, CA US

Patent application numberDescriptionPublished
20110182822Biomarkers for Painful Intervertebral Discs and Methods of Use Thereof - The present disclosure provides methods of diagnosing painful intervertebral discs. The present disclosure also provides methods of treating a painful intervertebral disc.07-28-2011
20140194364Biomarkers for Painful Intervertebral Discs and Methods of Use Thereof - The present disclosure provides methods of diagnosing painful intervertebral discs. The present disclosure also provides methods of treating a painful intervertebral disc.07-10-2014
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