Bryan A.
Bryan A. Branscome, Camano Island, WA US
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20100095624 | Apparatus and Method for Joining Building Components - A joint apparatus and method of assembly is disclosed for connecting building components such as panels, door jamb assemblies, windows and other structures. The apparatus includes an engagement structure with retaining elements that couple building components without the need for mechanical fasteners. The retaining element may contain serrations on which an adhesive is applied before a panel or other building component is secured to the joint apparatus. Other building components such as hinge assemblies include coupling members with a flange. The slots along a retaining element allows coupling members to snap fit into the joint apparatus once a flange is secured into the slots in order to lock the components. | 04-22-2010 |
20110062735 | PROTECTIVE KICK STRIP - In one embodiment, a kickstrip assembly comprises a base plate having a length extending along a longitudinal axis, and comprising an upper segment having an upper edge and an upper lip, a lower segment having a lower edge and a lower lip, the upper lip and the lower lip defining a middle section. The assembly further comprises an insert formed from a flexible polymeric material and comprising a faceplate, an upper edge depending from the faceplate, and a lower edge depending from the faceplate, wherein the faceplate is dimensioned to fit within middle section of the base plate. | 03-17-2011 |
Bryan A. Claseman, Buffalo, MN US
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20120165760 | DRUG ELUTING IMPLANT - Described herein is an implantable medical device that has one or more surfaces that include one or more shallow recesses configured to receive a drug delivery composition comprising a polymeric matrix and one or more biologically active agents. In one embodiment, one or more surfaces comprise a frictional surface. In a more particular embodiment, the implantable medical device comprises a stem configured for insertion into a bone of a patient, wherein the stem comprises one or more surfaces that include one or more shallow recesses configured to receive a drug delivery composition comprising a matrix and one or more biologically active agents. The drug delivery composition can be a durable drug delivery matrix, a biodegradable drug delivery matrix, or a combination thereof. Methods of making such an implant are also provided. | 06-28-2012 |
20140180229 | WOUND PACKING DEVICE AND METHODS - Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein. | 06-26-2014 |
Bryan A. Fiamengo, Worcester, MA US
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20090312338 | Novel Tricyclic Compounds - The invention provides a compound of Formula (I) | 12-17-2009 |
20130216497 | NOVEL TRICYCLIC COMPOUNDS - The invention provides compounds of Formula (I) and Formula (II) | 08-22-2013 |
20140349970 | NOVEL TRICYCLIC COMPOUNDS - The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. | 11-27-2014 |
Bryan A. Frieman, San Diego, CA US
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20110306607 | HETEROCYCLIC CHROMENE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 12-15-2011 |
20140171427 | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels - The invention relates to heterocyclic chromene-spirocyclic piperidine amides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 06-19-2014 |
Bryan A. Frieman, La Jolla, CA US
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20120245136 | CHROMAN-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to chroman spirocyclic piperidine amide derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 09-27-2012 |
20120264749 | MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 10-18-2012 |
20140309220 | BENZOXAZINES AS MODULATORS OF ION CHANNELS - The invention relates to benzoxazines useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 10-16-2014 |
20150025073 | MORPHOLINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS - The invention relates to morpholine spirocyclic piperidine amide compounds useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. | 01-22-2015 |
Bryan A. Frohriep, Roseville, MI US
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20100006520 | Kit And Shelving System To Store Work Tools, Equipment And Supplies In A Motor Vehicle And Plastic Shelf For Use Therein - A kit and shelving system to store work tools, equipment and supplies in a motor vehicle and plastic shelves for use therein are provided. Each of the shelves includes a reinforced composite panel of the cellular core sandwich-type. Each of the panels has front, back and side edge portions. Each of the shelves includes a first shelf support having an outer facing surface and an inner channel dimensioned to receive and retain a first one of the edge portions of the panel. The first edge portion of the panel is bonded to the first shelf support within the inner channel. | 01-14-2010 |
Bryan A. Grisso, Wickliffe, OH US
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20090221461 | Novel Polymers and Methods of Controlling Viscosity - The present invention relates to a novel polymer with pendant groups. The invention further provides for a lubricating composition containing said polymer. The invention further provides a method and use of controlling viscosity index by supplying to an oil of lubricating viscosity the polymer with pendant groups. | 09-03-2009 |
20090312210 | Lubricating Composition Containing a Polymer and Antiwear Agents - The invention provides a lubricating composition containing an oil of lubricating viscosity and polymer with pendant groups. The invention further provides for a method of controlling viscosity index by supplying to an oil of lubricating viscosity the polymer with pendant groups. | 12-17-2009 |
20130005628 | Novel Polymers and Methods of Controlling Viscosity - The present invention relates to a novel polymer with pendant groups. The invention further provides for a lubricating composition containing said polymer. The invention further provides a method and use of controlling viscosity index by supplying to an oil of lubricating viscosity the polymer with pendant groups. | 01-03-2013 |
Bryan A. Knuckley, Jacksonville, FL US
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20120295292 | Detecting Protein Arginine Deiminase (PAD) Activity in Human Tissues and Sera - Methods for diagnosing disease that is characterized by an overabundance of citrullinated proteins such as colitis, rheumatoid arthritis, and/or malignant cancer in a subject are provided. The PAD protein activity level can be measured in a tissue sample (e.g., serum) of the subject and then compared to a control PAD protein activity range of a control group. A finding of an increased PAD protein activity level in the tissue sample of the subject compared to the PAD protein activity level of the control group is indicative of disease characterized by an overabundance of citrullinated proteins in the subject. | 11-22-2012 |
Bryan A. Kuieck, Lowell, MI US
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20090084361 | DIESEL FUEL INJECTION PRIMING SYSTEM - A fuel injection priming system includes a fuel supply line connected to a fuel supply rail. A plurality of piezoelectric fuel injectors are connected to the fuel supply rail. An injector return fuel line is connected to the fuel injectors and in communication with a fuel supply line via a diverter valve to allow pressure fuel from the high pressure fuel pump return line to pressurize the injector return fuel line to backfill the injectors during a priming operation. A fuel restriction device is in communication with the diverter valve to restrict fuel flow through the injector return line to provide sufficient backfill for the fuel injectors during the priming operation and to allow fuel to pass to the fuel tank from the injector return fuel line during normal operation. | 04-02-2009 |
Bryan A. Kuieck, Estero, FL US
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20130047604 | INTERNAL COMBUSTION ENGINE AND METHOD FOR OPERATING INTERNAL COMBUSTION ENGINE - In one exemplary embodiment of the invention, an internal combustion engine includes a turbocharger configured to receive an air flow and a first exhaust flow from the internal combustion engine and a supercharger downstream of the turbocharger configured to receive a compressed air charge from the turbocharger. The engine further includes an exhaust gas recirculation circuit receiving a second exhaust flow from the internal combustion engine and supplying the second exhaust flow to the compressed air charge upstream of the supercharger, wherein the second exhaust flow and compressed air charge comprise an exhaust-air mixed flow received by the internal combustion engine. | 02-28-2013 |
20130174545 | CONTROL SYSTEMS AND METHODS FOR SUPER TURBO-CHARGED ENGINES - A method of controlling airflow of an engine system is provided. The method includes determining a supercharger operating mode and a turbocharger operating mode based on engine load; selectively generating a control signal to a turbocharger based on the turbocharger operating mode; and selectively generating a control signal to a supercharger bypass valve based on the supercharger operating mode. | 07-11-2013 |
Bryan A. Lynchard, Cookeville, TN US
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20140083922 | ANTI-ROTATION KNURLS - A filter assembly that includes a shell having anti-rotation features that prevent rotation of the shell relative to the nutplate and a method for producing the disclosed filter assembly are described. The anti-rotation features are knurls and/or surface disruptions that are formed on a surface of a flange on an open end of the shell. The knurls and/or surface disruptions that are formed on a surface on the flange can aid in gripping a surface of an upper groove of the nutplate. | 03-27-2014 |
Bryan A. Patel, Jersey City, NJ US
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20150101406 | REAL-TIME LEVEL MONITORING FOR FIXED BED CATALYST LOADING USING MULTIPLE LEVEL SENSORS - In various aspects, methods and systems are provided for monitoring catalyst bed levels using multiple sensors that are temporarily installed in a reactor during catalyst loading. The multiple sensors are able to take distance measurements at substantially the same time and at predetermined time intervals so as to provide a catalyst time profile. The catalyst time profile allows an operator monitor catalyst levels during and after catalyst loading. Once catalyst loading is completed, the multiple sensors are removed from the reactor. | 04-16-2015 |
Bryan A. Paulet, Spring, TX US
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20130181844 | INSTRUMENTED ROD ROTATOR - Methods and apparatus are provided for monitoring the rotation of a member in a reciprocating rod lift system. In this manner, rod and tubing wear of the system may be minimized. | 07-18-2013 |
20140305636 | SENSING IN ARTIFICIAL LIFT SYSTEMS - Methods and apparatus are provided for measuring one or more parameters associated with an artificial lift system for hydrocarbon production and operating the system based on the measured parameters. One embodiment of the invention provides a lubricator for a plunger lift system, which generally includes a housing, a spring disposed in the housing for absorbing an impact by a plunger, and a sensor configured to measure at least one parameter of the spring. One example method of operating a plunger lift system for hydrocarbon production generally includes measuring at least one parameter of a spring disposed in a lubricator of the plunger lift system and operating the plunger lift system based on the measured parameter. | 10-16-2014 |
Bryan A. Roecklein, Somerset, NJ US
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20100152147 | Compositions Comprising Azelastine and Methods of Use Thereof - The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent. The invention also generally relates to pharmaceutical compositions comprising one or more active pharmaceutical ingredients, such as azelastine or pharmaceutically acceptable salts or esters thereof including azelastine hydrochloride, particularly wherein the compositions are provided in unit dosage form. In certain embodiments, the invention provides such unit dosage pharmaceutical compositions comprising azelastine hydrochloride formulated for use as nasal sprays and/or ocular solutions or drops. The invention also provides methods of treating or preventing certain disorders, or symptomatic relief therefrom, by administering the compositions of the invention to a patient, e.g., for the symptomatic relief of a variety of allergic and non-allergic conditions, particularly conjunctivitis, sinusitis, rhinitis and rhinosinusitis. The compositions and methods of the present invention provide significant value in terms of patient acceptability, convenience, and compliance. | 06-17-2010 |
Bryan A. Roecklein, Belle Mead, NJ US
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20100189782 | Compositions Comprising Carisoprodol and Methods of Use Thereof - The present invention provides compositions comprising carisoprodol or pharmaceutically acceptable salts, esters or derivatives thereof. In certain embodiments, the invention provides pharmaceutical compositions comprising the skeletal muscle relaxant carisoprodol and one or more additional active agents, such as one or more nonsteroidal antiinflammatory drugs (NSAIDs). The invention further provides methods of use of such compositions in preventing, alleviating and/or treating musculoskeletal pain, muscle spasms, or other non-malignant painful conditions including methods in which the circulating levels of the active pharmaceutical form of carisoprodol are controlled by use of extended- or controlled-release formulations or by strict control of dosage regimen, so as to reduce the level of somnolence observed with other muscle relaxant compositions. | 07-29-2010 |
Bryan A. Stear, Ann Arbor, MI US
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20150184985 | Tapered Shooting Range - A design for a shooting range with tapered shooting lanes or zones is disclosed. The shooting lanes are wider at the position of the shooter than they are at the end of the range, thereby resulting in a design that is cheaper to build and easier to maintain. The tapering of the lanes can be in the horizontal or vertical directions (or both). This design can be used in indoor or outdoor ranges, with firearms, bows, crossbows, air rifles, air softs, and other types of projectiles that are fired, shot, or launched. | 07-02-2015 |