Browne, CA
Aidan Browne, Murrieta, CA US
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20130345658 | METHOD AND APPARATUS FOR DETECTION AND MANAGEMENT OF AIR-IN-LINE - In an infusion pump operable to deliver fluid to a patient at a programmed therapy flow rate, air-in-line sensing is improved by commanding the pumping mechanism to deliver a bolus volume of fluid at a flow rate higher than the therapy flow rate when an uninterrupted volume of air is detected that exceeds a first threshold. In many cases, the bolus will be effective to clear microbubbles from an observation zone of the air-in-line sensor to avoid an air-in-line alarm condition. If the uninterrupted volume of air continues to grow beyond a second threshold in spite of the bolus, then an alarm may be triggered. The invention reduces false alarms. | 12-26-2013 |
Dan Browne, Palo Alto, CA US
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20120148562 | METHODS AND COMPOSITIONS FOR TREATING SKIN CONDITIONS ASSOCIATED WITH VASCULAR HYPER-REACTIVITY - The present invention provides a methods and compositions for treating a patient having a skin condition characterized by vascular hyper-reactivity, such as chronic or episodic flushing or blushing, and/or rosacea. The method comprises applying a topical composition to affected areas of the patient's skin. The topical composition comprises an effective amount of a botulinum neurotoxin for decreasing vasodilation in cutaneous microvasculature, and a carrier for effectively transporting the botulinum toxin to the cutaneous microvasculature. The invention thereby provides a safe, effective, comfortable, and/or convenient manner of treating vascular hyper-reactivity in skin. | 06-14-2012 |
Daniel Browne, Palo Alto, CA US
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20080215088 | Systems, Methods, and compositions for achieving closure of suture sites - Systems and methods employ functional instruments to close incisions and wounds using a suture knot in combination with a biocompatible material composition. The systems and methods are well suited for use, for example, at a vascular puncture site following a vascular access procedure. | 09-04-2008 |
Dean Browne, San Carlos, CA US
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20120278185 | METHOD TO ADAPT ADS RENDERED IN A MOBILE DEVICE BASED ON EXISTENCE OF OTHER MOBILE APPLICATIONS - A method, apparatus and computer-readable storage medium for adapting alternative documents associated with content to be rendered in a mobile device is disclosed. A method, apparatus and computer-readable storage medium for adapting content, such as ads, based on presence or absence of certain mobile applications is disclosed. The mobile device performs receiving a group of contents together with condition code for each respective content. The mobile device checks a condition code, which includes examining the set of mobile applications contained in the mobile device, selecting and showing the content whose condition code specifying presence or absence of a set of mobile applications is met. A server computer is disclosed for serving a requested content based on checking a condition code. A client front-end is disclosed that enables specifying an ordered sequence of alternative documents or specifying conditions to be met in order to show respective content from a group. | 11-01-2012 |
Denis Browne, San Mateo, CA US
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20120287088 | METHOD AND SYSTEM FOR COMBINING PAPER-DRIVEN AND SOFTWARE-DRIVEN DESIGN PROCESSES - A method and system for combining paper-driven and software-driven design processes is provided. An example system comprises a request detector, a stroke analyzer, and a UI definition updater. The request detector may be configured to detect a request to process a change to a UI definition. The stroke analyzer may be configured to access a stroke generated by a digital pen and determine, from the stroke, a new element to be appended to a page in the UI definition. The UI definition updater may be configured to update the UI definition, e.g., by including the new element at the target location. | 11-15-2012 |
Denis J. Browne, San Mateo, CA US
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20080215998 | WIDGET LAUNCHER AND BRIEFCASE - A system and method for persistently associating a control widget with a plurality of managed widgets operating within a widget runtime environment; changing a state of the managed widgets as a group, the state including one of open, closed, or hidden; and representing the changed state of the managed widgets via a display. Managed widgets having a closed state are neither displayed nor connected with a data source, widgets having an open state are both displayed and connected with a data source, and widgets having an intermediate state are not displayed (e.g. hidden) but are connected with a data source and capable of receiving updated information while hidden. | 09-04-2008 |
Gregory Browne, Davis, CA US
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20080320618 | Walnut rootstock 'VX211' - A new and distinct variety of walnut rootstock denominated ‘VX211’ is described. This new variety, ‘VX211’, can be propagated through micropropagation or rooted cuttings. ‘VX211’ has vigor and survivability in the nursery and in the orchard. It has reduced susceptibility to damage from nematodes ( | 12-25-2008 |
20080320619 | Walnut rootstock 'RX1' - A new and distinct variety of walnut rootstock denominated ‘RX1’ is described. This new variety, ‘RX1’, can be propagated through micropropagation. It has excellent survivability in the nursery and orchard. The new variety also has reduced susceptibility to damage from | 12-25-2008 |
Gregory V. Browne, Victoria, CA US
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20160139159 | DEVICES, SYSTEMS AND METHODS FOR EVALUATION OF HEMOSTASIS - Provided are devices, systems and methods for evaluation of hemostasis. Also provided are sound focusing assemblies. | 05-19-2016 |
Ian Browne, Irvine, CA US
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20140170482 | ELECTRODES, ELECTROCHEMICAL CELLS, AND METHODS OF FORMING ELECTRODES AND ELECTROCHEMICAL CELLS - Electrodes and methods of forming electrodes are described herein. The electrode can be an electrode of an electrochemical cell or battery. The electrode includes a current collector and a film in electrical communication with the current collector. The film may include a carbon phase that holds the film together. The electrode further includes an electrode attachment substance that adheres the film to the current collector. | 06-19-2014 |
Ian R. Browne, Irvine, CA US
Patent application number | Description | Published |
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20140166939 | SILICON PARTICLES FOR BATTERY ELECTRODES - Silicon particles for active materials and electro-chemical cells are provided. The active materials comprising silicon particles described herein can be utilized as an electrode material for a battery. In certain embodiments, the composite material includes greater than 0% and less than about 90% by weight of silicon particles. The silicon particles have an average particle size between about 0.1 μm and about 30 μm and a surface including nanometer-sized features. The composite material also includes greater than 0% and less than about 90% by weight of one or more types of carbon phases. At least one of the one or more types of carbon phases is a substantially continuous phase. | 06-19-2014 |
20140170475 | ELECTRODES, ELECTROCHEMICAL CELLS, AND METHODS OF FORMING ELECTRODES AND ELECTROCHEMICAL CELLS - Electrodes and methods of forming electrodes are described herein. The electrode can be an electrode of an electrochemical cell or battery. The electrode includes a current collector and a film in electrical communication with the current collector. The film may include a carbon phase that holds the film together. The electrode further includes an electrode attachment substance that adheres the film to the current collector. | 06-19-2014 |
20140295290 | ELECTRODES, ELECTROCHEMICAL CELLS, AND METHODS OF FORMING ELECTRODES AND ELECTROCHEMICAL CELLS - Electrodes and methods of forming electrodes are described herein. The electrode can be an electrode of an electrochemical cell or battery. The electrode includes a current collector and a film in electrical communication with the current collector. The film may include a carbon phase that holds the film together. The electrode further includes an electrode attachment substance that adheres the film to the current collector. | 10-02-2014 |
Ioana Browne, Palo Alto, CA US
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20140220853 | Geometric Systems for Building 3-D Structures - Geometric systems for building 3-D structures from a plurality of 2-D building elements, including a first building element defining a first shape defined by edges with a first dimension, and a second building element defining a second shape incongruent to the first shape defined by edges with a second dimension incongruent to the first dimension. Further, each building element defines an imaginary circle having a center aligned with the center of the building element, and defines a plurality of notches positioned at and tangential to the circumference of the imaginary circle, where the plurality of building elements are configured to fit together at their respective notches to torn a 3-D structure. Geometric systems may include a first building element defining a first shape with a first contour, and a second building element defining a second shape incongruent to the first shape with a second contour incongruent to the first contour. | 08-07-2014 |
20150099417 | GEOMETRIC SYSTEMS FOR BUILDING 3-D STRUCTURES - Geometric systems including 2-D building elements configured to connect together for building 3-D structures, the of 2-D building elements each have a body that is at least: a central main body, tabs extended away from the central main body, and notches, one of the notches being disposed between each of the tabs and the central main body are described. The notches are oriented to form an underlying polygon of the central main body, and a width of each of the tabs is no greater than one half a length of one side of the underlying polygon. In some examples, where each of the tabs is comprised of a substantially rigid material, the width of the tab is no greater than one third the length of one side of the underlying polygon. In other examples, where each of the tabs is comprised of a substantially flexible material, the width of the tab is no less than one third the length of one side of the underlying polygon. | 04-09-2015 |
Jason Browne, Menlo Park, CA US
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20130196685 | WEB SERVER AND METHOD FOR HOSTING A WEB PAGE FOR PRESENTING LOCATION BASED USER QUALITY DATA RELATED TO A COMMUNICATION NETWORK - A computing device forms a predictive composite score by retrieving geographically based wireless networking performance data derived from at least one mobile device. At least some of the geographically based wireless networking performance data is temporally averaged and geostatistically combined to form the predictive composite score. The predictive composite score is a forecast of expected performance quality of a wireless communication network in a particular geographic region. | 08-01-2013 |
20150319048 | WEB SERVER AND METHOD FOR HOSTING A WEB PAGE FOR PRESENTING LOCATION BASED USER QUALITY DATA RELATED TO A COMMUNICATION NETWORK - A web-server communicates wireless networking performance data that reflects the true user experience of a mobile device operating in a particular location and operating on a particular wireless network. | 11-05-2015 |
20150341226 | WEB SERVER AND METHOD FOR HOSTING A WEB PAGE FOR PRESENTING LOCATION BASED USER QUALITY DATA RELATED TO A COMMUNICATION NETWORK - A computing device forms a predictive composite score by retrieving geographically based wireless networking performance data derived from at least one mobile device. At least some of the geographically based wireless networking performance data is temporally averaged and geostatistically combined to form the predictive composite score. The predictive composite score is a forecast of expected performance quality of a wireless communication network in a particular geographic region. | 11-26-2015 |
Jason Browne, San Mateo, CA US
Patent application number | Description | Published |
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20100087188 | MOBILE DEVICE AND METHOD FOR COLLECTING LOCATION BASED USER QUALITY DATA - A mobile device executes software. The software collects realistic and accurate user quality information without degrading the user experience of the mobile device during the data collection process. The software operates as a background application, and may have a user interface, and the software is remotely controllable and updatable by an external server. | 04-08-2010 |
20100091677 | WEB SERVER AND METHOD FOR HOSTING A WEB PAGE FOR PRESENTING LOCATION BASED USER QUALITY DATA RELATED TO A COMMUNICATION NETWORK - A web-server communicates wireless networking performance data that reflects the true user experience of a mobile device operating in a particular location and operating on a particular wireless network. | 04-15-2010 |
20100094930 | SERVER DEVICE AND METHOD FOR DIRECTING MOBILE DEVICES TO COLLECT AND COMMUNICATE LOCATION BASED USER QUALITY DATA - A computing server directs a mobile device to collect and communicate realistic and accurate user quality information according to a data collection rule. The computing server receives, filters, and stores the user quality information in a database. The computing server processes the data and communicates the data to a web-server. | 04-15-2010 |
20100114668 | Determining Relative Effectiveness Of Media Content Items - The effectiveness of advertisements with respect to a group of panelists is measured. Based on the results of such analysis, advertisements and/or variants thereof are selected for presentation to consumers. Effectiveness of advertisements is measured, in one embodiment, by detecting exposure to advertisements, and then monitoring panelist behavior following exposure to an advertisement. In one embodiment, the group of panelists is a representative sample of a larger population, so that observations of panelist behavior can be used as a basis for making decisions regarding presentation of advertisements to a larger audience having characteristics similar to those of the panelists. | 05-06-2010 |
20120172023 | MOBILE DEVICE AND METHOD FOR COLLECTING LOCATION BASED USER QUALITY DATA - A mobile device executes software. The software collects realistic and accurate user quality information without degrading the user experience of the mobile device during the data collection process. The software operates as a background application, and may have a user interface, and the software is remotely controllable and updatable by an external server. | 07-05-2012 |
20130132517 | WEB SERVER AND METHOD FOR HOSTING A WEB PAGE FOR PRESENTING LOCATION BASED USER QUALITY DATA RELATED TO A COMMUNICATION NETWORK - A web-server communicates wireless networking performance data that reflects the true user experience of a mobile device operating in a particular location and operating on a particular wireless network. | 05-23-2013 |
Jeffrey Browne, Santa Barbara, CA US
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20120229468 | INTEGRATION OF SKETCH-BASED INTERACTION AND COMPUTER DATA ANALYSIS - Architecture that integrates the benefits of natural user interaction such as freeform sketch with computer-aided charting. The architecture integrates natural user interaction utilizing multiple modalities (e.g., sketch, multi-touch, etc.) with computer supported data analysis that allows users to explore data by drawing charts using simple strokes. Natural user interactions can be utilized to change chart types by drawing symbols, transform data by applying functions, filter data by drawing strikethrough on legends, etc. Additionally, the architecture makes an inference of visualizations the user intended from user-drawn strokes, such as the axes of a graph, the words of a label, etc. When appropriate, the architecture automatically completes visualizations. | 09-13-2012 |
Jeffrey C. Browne, San Francisco, CA US
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20150271446 | SHARING PHYSICAL WHITEBOARD CONTENT IN ELECTRONIC CONFERENCE - A technique for sharing a physical target board over an electronic conference includes transforming live video from a webcam into output video that provides an enhanced view of the physical target board. The output video is shared with one or more computing machines of conference participants to enable such participants to see the enhanced view of the physical target board in real time. The conference participants can thus enjoy enhanced images of the physical board and its content, which would otherwise be difficult or impossible to see. | 09-24-2015 |
Jeffrey Casper Browne, San Francisco, CA US
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20160050504 | Utilizing a Smartphone During a Public Address System Session - A technique utilizes a smartphone during a public address system session. The technique involves operating a public address system to provide audio from a local human presenter to a local human audience, the local human presenter and the local human audience residing at a common physical public address location. The technique further involves establishing, while operating the public address system to provide audio from the local human presenter to the local human audience, an electronic connection between the smartphone and the public address system. The technique further involves providing, after establishing the electronic connection between the smartphone and the public address system, audio from a user of the smartphone to the local human audience through the smartphone, the electronic connection, and the public address system. | 02-18-2016 |
Jeffrey K. Browne, Camarillo, CA US
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20090017137 | Methods and compositions for the prevention and treatment of anemia - Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythropoietin analogs, methods of production of the analogs, and compositions comprising the analogs. | 01-15-2009 |
20090023636 | Methods and compositions for the prevention and treatment of anemia - Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs. | 01-22-2009 |
20110256586 | Methods and Compositions for the Prevention and Treatment of Anemia - Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs. | 10-20-2011 |
20120322730 | METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ANEMIA - Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently than an equivalent molar amount of recombinant human erythropoietin to obtain a comparable target hematocrit and treat anemia. Alternatively, a lower molar amount of a hyperglycosylated analog may be administered to obtain a comparable target hematocrit and treat anemia. Also disclosed are new hyperglycosylated erythopoietin analogs, methods of production of the analogs, and compositions comprising the analogs. | 12-20-2012 |
John P. Browne, Larkspur, CA US
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20140279455 | MERCHANT MANAGED SUBSCRIPTIONS AT A BILLING SERVER - A system and method is described for managing subscriptions between a consumer mobile phone, merchant server, billing server and carrier server. A charge-info method is used for the merchant server to retrieve charge elements from the billing server for constructing a user interface for the consumer mobile phone. An opt-in method is used to confirm a consumer's opt-in for a subscription. A remind-charge method is used to remind the consumer of an upcoming charge on the subscription. A charge method allows the merchant server to charge a user account on a carrier server via the billing server. A cancel method is used for the consumer to cancel the subscription. | 09-18-2014 |
20140279456 | MERCHANT MANAGED SUBSCRIPTIONS AT A MERCHANT SERVER - A system and method is described for managing subscriptions between a consumer mobile phone, merchant server, billing server and carrier server. A charge-info method is used for the merchant server to retrieve charge elements from the billing server for constructing a user interface for the consumer mobile phone. An opt-in method is used to confirm a consumer's opt-in for a subscription. A remind-charge method is used to remind the consumer of an upcoming charge on the subscription. A charge method allows the merchant server to charge a user account on a carrier server via the billing server. A cancel method is used for the consumer to cancel the subscription. | 09-18-2014 |
20140323082 | BILLING GATEWAY CHARGE METHOD AND SYSTEM - The billing gateway charge method and system are disclosed. A charge is processed by receiving a charge API call from a merchant server, detecting a select carrier server from a plurality of servers, transmitting a charge request to the select carrier server, and returning a charge result callback notification to the merchant server. If the charge request fails, the merchant server can submit a new request and an indication of acceptance and failure of the charge request is returned to the merchant server based on the new requests provided that the new request has a new request-id. A continue method allows for managing consumer opt-in in order to complete a transaction. Once the transaction is completed, a refund request from the merchant server can be processed by transmission to the carrier server. | 10-30-2014 |
20140324696 | BILLING GATEWAY AUTHORIZE-AND-CAPTURE METHOD AND SYSTEM - A transaction is authorized by receiving an authorize API call from a merchant server, detecting a select carrier server, and transmitting an authorize request to the select carrier server. The carrier server will then reserve an amount of funds based on the authorization request. The authorized transaction is then recorded based on the authorize request. The consumer may then request to cancel the transaction. If a capture request is received, a determination is made whether the cancel request has been received and whether the authorized transaction has been cancelled. If the transaction has not been cancelled, a billing request is transmitted to the carrier server so that the carrier server charges for the transaction. | 10-30-2014 |
20150058221 | TEXT-TO-PAY FOR REDEEMABLE CODES - A method and system of processing a sale of an article, a virtual article, a service or a functionality such as a game is described. A code is generated by a server. A charge request is transmitted to an account server to charge an account of a user for a value of the code. The code is transmitted to a user device. The code is then processed by redeeming the code, wherein redemption of the code includes receiving the code from a user device and in response allowing access to the user device to the article, virtual article, a service or a functionality. | 02-26-2015 |
Jolyon Browne, San Jose, CA US
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20160084984 | Systems and Methods For The Automatic Detection of Lithium Batteries in Cargo, Baggage, Parcels, and Other Containers - The present specification discloses methods for scanning objects for the presence of lithium batteries. Normalized transmission X-ray data is used to generate organic, effective Z, and attenuation-based images. These images are then segmented using a combination of thresholding and region growing techniques to identify regions of interest. The regions are classified as lithium batteries or other objects, based on characteristics such as area of the region, its organic intensity, Z | 03-24-2016 |
Jolyon A. Browne, San Jose, CA US
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20100295689 | Systems and Methods for Automated, Rapid Detection of High-Atomic-Number Materials - The present invention is directed to an inspection system that has a radiation source, a detector array, an inspection region, and a processing unit, where the processing unit a) obtains a radiographic image, b) segments the radiographic image based on radiation attenuation or transmission, c) identifies at least one segmented area on the radiographic image, d) filters the at least one segmented area using at least one geometric filter, e) generates feature vectors using the filtered segmented area; and f) compares the feature vectors against predefined values to determine whether a high-atomic-number object is present. | 11-25-2010 |
Kenneth A. Browne, San Diego, CA US
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20110020824 | METHODS AND COMPOSITIONS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE - Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons and their ratios to one another are chosen to span the required linear dynamic range for the amplification reaction and to accommodate limitations of the measuring system used to determine the amount of amplicon generated. Unequal amounts of distinguishable amplicon species are generated by providing unequal amounts of one or more amplification reaction components (e.g., distinguishable amplification oligomers, natural and unnatural NTP in an NTP mix, or the like). The amount of target nucleic acid present in a test sample is determined using the linear detection range generated from detection of one or more amplicon species having an amount within the dynamic range of detection. | 01-27-2011 |
Kenneth A. Browne, Poway, CA US
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20120231459 | CHEMILUMINESCENT PROBES FOR MULTIPLEX MOLECULAR QUANTIFICATION AND USES THEREOF - A novel method is disclosed for simultaneous detection and quantification of two or more nucleic acid targets, without need for amplification. The method depends on spectral-temporal resolution of chemiluminescence emitted from independent hybridization-induced chemiluminescent signal (HICS) probes. The utility of this method has been demonstrated by use of resolvable N-linked acridinium and 2,7-dimethoxyacridinium ester labeled probes in a homogeneous assay for sensitive and simultaneous independent quantification of several bacterial and fungal target sequences. Compositions and kits for practicing the method of the present invention are also disclosed. | 09-13-2012 |
20120260951 | SOLUTIONS, METHODS AND KITS FOR DEACTIVATING NUCLEIC ACIDS - The present invention relates to reagents for use in deactivating nucleic acids and methods of making and using the same. | 10-18-2012 |
20130040859 | SPECTRALLY-RESOLVED CHEMILUMINESCENT PROBES FOR SENSITIVE MULTIPLEX MOLECULAR QUANTIFICATION - Hybrid luminescent probes emit light of distinct wavelength ranges and intensities upon energy transfer from an in-common, acridinium ester chemiluminophore to a coupled luminophore. The probes include: (1) a target binding region with a base sequence that is substantially complementary to a portion of the target nucleic acid sequence; (2) an acridinium ester (AE) moiety attached to a first region flanking the target binding region; (3) a luminophore coupled to the AE moiety to allow energy transfer from an acridone moiety, produced by a chemical triggering of the AE moiety, to the luminophore; and (4) a quencher moiety attached to a second region flanking the target binding region, such that the first and second flanking regions are on the opposite sides of the target binding region. The probes are particularly useful in homogeneous assays for sensitive, multiplex quantification of nucleic acid target sequences without prior enzymatic amplification. | 02-14-2013 |
20140072974 | METHODS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE - Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons and their ratios to one another are chosen to span the required linear dynamic range for the amplification reaction and to accommodate limitations of the measuring system used to determine the amount of amplicon generated. Unequal amounts of distinguishable amplicon species are generated by providing unequal amounts of one or more amplification reaction components (e.g., distinguishable amplification oligomers, natural and unnatural NTP in an NTP mix, or the like). The amount of target nucleic acid present in a test sample is determined using the linear detection range generated from detection of one or more amplicon species having an amount within the dynamic range of detection. | 03-13-2014 |
20140231710 | METHOD OF MAKING A FORMULATION FOR DEACTIVATING NUCLEIC ACIDS - The disclosure relates to formulations for use in deactivating nucleic acids and methods of making and using the same. | 08-21-2014 |
20140239223 | METHOD OF MAKING A FORMULATION FOR DEACTIVATING NUCLEIC ACIDS - The disclosure relates to formulations for use in deactivating nucleic acids and methods of making and using the same. | 08-28-2014 |
20150093753 | METHODS FOR QUANTITATIVE AMPLIFICATION AND DETECTION OVER A WIDE DYNAMIC RANGE - Disclosed are compositions and methods for making differentiable amplicon species at unequal ratios using a single amplification system in a single vessel. The number of differentiable amplicons and their ratios to one another are chosen to span the required linear dynamic range for the amplification reaction and to accommodate limitations of the measuring system used to determine the amount of amplicon generated. Unequal amounts of distinguishable amplicon species are generated by providing unequal amounts of one or more amplification reaction components (e.g., distinguishable amplification oligomers, natural and unnatural NTP in an NTP mix, or the like). The amount of target nucleic acid present in a test sample is determined using the linear detection range generated from detection of one or more amplicon species having an amount within the dynamic range of detection. | 04-02-2015 |
L. Daniel Browne, Palo Alto, CA US
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20130251770 | Method of Treatment of Wrinkles Using Topical Chemodenervating Agents - Methods for reducing the appearance of wrinkles in a subject are provided herein. The methods of the present invention comprise identifying a wrinkle distribution on a subject and applying a topical composition comprising at least one chemodenervating agent onto and along the wrinkle distribution. The methods disclosed herein provide alternative methods for delivery of chemodenervating agents to the skin for the treatment of wrinkles. | 09-26-2013 |
Michael P. Browne, San Mateo, CA US
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20120257005 | High Resolution Wide Field of View Digital Night Vision System - A wide field of view night vision system is described. The system comprises a head attachment apparatus configured to attach to a user's head and a night vision subsystem. The night vision subsystem comprises one or more night vision image sensors attached to the head attachment apparatus. Each sensor receives input light and produces a digital image of the input light. A processor processes the digital image(s) to produce a wide-field image. The wide-field image spans at least 60 degrees of a user's horizontal field of view. A display and eyepiece attached to the head attachment apparatus receives and displays the wide-field image. The eyepiece is positionable between the display and the user's eye to image the wide-field image into the user's eye. | 10-11-2012 |
Mike Browne, Rochester Hills, CA US
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20160039277 | Hybrid Axle Assembly For A Motor Vehicle - An axle assembly for an electric or hybrid vehicle includes electrically powered drive motors for respectively driving vehicle wheels. The axle assembly preferably includes a dual motor arrangement, wherein two electric motors are arranged end-to-end. Each motor includes an inverter that is directly connected to its respective motor, and includes a gearbox assembly coupled between an output of the motor and a corresponding constant-velocity (CV) joint operatively connected to a wheel. The inboard ends of the motors are secured to opposite faces of a cooling manifold wherein the cooling manifold maintains the motors in axial alignment. The cooling manifold plate is positioned between an inboard end of each of the motor housings, and the cooling manifold plate axially aligns the first and second motors. Further, each motor drives its respective gearbox assembly, which includes a gear reduction and clutch mechanism having a brake band assembly that is selectively operable to disconnect the respective motor from the vehicle wheel associated therewith. | 02-11-2016 |
Mike Browne, Palo Alto, CA US
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20110103389 | METHOD AND APPARATUS FOR SWITCHING TRAFFIC BETWEEN VIRTUAL MACHINES - Systems and methods for switching traffic include a physical machine running source and destination virtual machines (VMs). The source VM issues a data unit addressed to the destination VM. The physical machine has a physical network interface in communication with the VMs. The physical network interface transmits a sub-packet, which includes a partial portion of the data unit, over a network while a majority portion of the data unit remains at the physical machine. A network switch on the network receives the sub-packet transmitted by the physical network interface. The network switch performs one or more OSI Layer 2 through Layer 7 switching functions on the sub-packet and returns that sub-packet to the physical network interface. The physical network interface identifies the data unit stored in the memory in response to the sub-packet returned from the network switch and forwards the identified data unit to the destination VM. | 05-05-2011 |
20120209940 | METHOD FOR SWITCHING TRAFFIC BETWEEN VIRTUAL MACHINES - Methods for switching traffic include a physical machine running source and destination virtual machines (VMs). The source VM issues a data unit addressed to the destination VM. The physical machine has a physical network interface in communication with the VMs. The physical network interface transmits a sub-packet, which includes a partial portion of the data unit, over a network while a majority portion of the data unit remains at the physical machine. A network switch on the network receives the sub-packet transmitted by the physical network interface. The network switch performs one or more OSI Layer 2 through Layer 7 switching functions on the sub-packet and returns that sub-packet to the physical network interface. The physical network interface identifies the data unit stored in the memory in response to the sub-packet returned from the network switch and forwards the identified data unit to the destination VM. | 08-16-2012 |
Niall Browne, Redwood City, CA US
Patent application number | Description | Published |
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20140181898 | SYSTEM AND METHOD FOR IMPLEMENTING ADAPTIVE SECURITY ZONES - A system for managing adaptive security zones in complex business operations, comprising a rules engine adapted to receive events from a plurality of event sources and a security manager coupled to the rules engine via a data network, wherein upon receiving an event, the rules engine determines what rules, if any, are triggered by the event and, upon triggering a rule, the rules engine determines if the rule pertains to security and, if so, sends a notification message to the security manager informing it of the triggered event, and wherein the security manager, on receiving a notification message from the rules engine, automatically establishes a new security zone based at least in part on the contents of the notification message, is disclosed. | 06-26-2014 |
Niall Browne, Red Wood City, CA US
Patent application number | Description | Published |
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20110099602 | System and method for implementing adaptive security zones - A system for managing adaptive security zones in complex business operations, comprising a rules engine adapted to receive events from a plurality of event sources and a security manager coupled to the rules engine via a data network, wherein upon receiving an event, the rules engine determines what rules, if any, are triggered by the event and, upon triggering a rule, the rules engine determines if the rule pertains to security and, if so, sends a notification message to the security manager informing it of the triggered event, and wherein the security manager, on receiving a notification message from the rules engine, automatically establishes a new security zone based at least in part on the contents of the notification message, is disclosed | 04-28-2011 |