Brown, London
Alex Brown, London GB
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20150218289 | ANTI-TRANSGLUTAMINASE 2 ANTIBODIES - The invention provides antibodies and antigen-binding fragments thereof that selectively bind to an epitope within the core region of transglutaminase type 2 (TG2). Novel epitopes within the TG2 core are provided. The invention provides human TG2 inhibitory antibodies and uses thereof, particularly in medicine, for example in the treatment and/or diagnosis of conditions including Celiac disease, scarring, fibrosis-related diseases, neurodegenerative/neurological diseases and cancer. | 08-06-2015 |
André Brown, London GB
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20150317718 | Defining a Selection Process - A selection process is defined for items provided by an e-commerce site to shoppers' web browsers. One or more selection attributes are identified for each e-commerce shop item. A selection function is defined in association with each selected attribute. At least one rule is defined for combining one or many of selection scores from respective selection functions to obtain an item score. The selection process is then defined as selecting items in response to the item scores. | 11-05-2015 |
Arthur Brown, London CA
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20100028364 | INHIBITION OF SOX9 FUNCTION IN THE TREATMENT OF PROTEOGLYCAN-ASSOCIATED PATHOPHYSIOLOGICAL CONDITIONS - A method of treating a pathophysiological condition caused by the production of growth-inhibiting proteoglycans is provided. It is based on the finding that down-regulation of SOX9 results in decreased production of growth-inhibiting factors such as proteoglycans, and increased production of growth-promoting factors such as a laminin and fibronectin. The method of the present invention comprises the inhibition of SOX9 expression and function with an inhibitor such as an antisense oligonucleotide or a siRNA. | 02-04-2010 |
20130266663 | SOX9 INHIBITORS - Methods for treating a condition associated with proteoglycan production in a mammal are provided. The methods comprise the administration of at least one of a calmodulin antagonist, a transient receptor potential (TRP) channel inhibitor and a calmodulin-binding peptide to the mammal. | 10-10-2013 |
Carlton B. Brown, London GB
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20140234356 | INFLUENZA ANTIGEN DELIVERY VECTORS AND CONSTRUCTS - The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans. | 08-21-2014 |
20150112042 | Antigen Delivery Vectors and Constructs - The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals. | 04-23-2015 |
Carlton Bradley Brown, London GB
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20160106830 | VACCINES AGAINST HEPATITIS B VIRUS - A pharmaceutical composition comprising at least two peptides of from 15 to 60 amino acids in length, selected from peptides comprising a sequence of at least 15 contiguous amino acids of one of the sequences shown in SEQ ID NOs: 1 to 4 or of a sequence having at least 80% identity to one of the sequences shown in SEQ ID NOs: to 4, wherein each peptide comprises at least one CD8+ T-cell epitope and/or at least one CD4+ T-cell epitope and wherein each peptide elicits a response in peripheral blood mononuclear cells (PBMC) from at least one chronically infected HBV individual in an 10 in vitroassay. | 04-21-2016 |
Darren Mark Brown, London GB
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20130125301 | TOILET - A toilet, wherein: the toilet has an aperture ( | 05-23-2013 |
Giles Brown, London GB
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20130289020 | CXCR4 Receptor Antagonists - Disclosed are compounds that are antagonists of the CXCR4 receptor. | 10-31-2013 |
20160046606 | CXCR4 Receptor Antagonists - The compounds of formula (I) are antagonists of the CXCR4 receptor | 02-18-2016 |
Glenn Brown, London GB
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20150052450 | Displaying Hierarchies of Artifacts - Among other things, we describe receiving, from a user, a first criterion for arranging a set of artifacts in a first hierarchy including a first arrangement, the artifacts being stored in an archive in a second arrangement, and displaying, in a user interface, a level of the first hierarchy including a subset of the artifacts, the subset of the artifacts having a common feature identified based on the first criterion. | 02-19-2015 |
Jeremy Stuart Brown, London GB
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20090280141 | Streptococcal Genes - Peptides derived from | 11-12-2009 |
John Brown, London GB
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20110024263 | PAPER HANDLING APPARATUS - A paper handling apparatus comprising: a plurality of feeder stations, for feeding documents to a conveyer, means for collating documents into packs, and means for collating packs into groups of documents, and an inserter module for inserting each group into an envelope, further comprising: means for monitoring the cycling and working times of sections of the inserter module, and means for determining at least one of: a first desired gap being the minimum gap between trailing edges of consecutive groups; a second desired gap being the minimum gap between the trailing edge of one pack and the leading edge of the following pack; a third desired gap being the minimum gap between the trailing edge of one group to the leading edge of the following group; and means for controlling at least one of the feeder stations to achieve at least one of the respective desired gaps. | 02-03-2011 |
20110031682 | TRANSPORT SYSTEM - A method for controlling a variable speed transport system for moving a plurality of documentary items at a predetermined speed, acceleration and deceleration the method comprising: determining a mass of each pack of documents; using the determined mass to determine a maximum speed, acceleration and deceleration; and adjusting the predetermined speed acceleration and deceleration in dependence upon the determined maximum speed, acceleration and deceleration. | 02-10-2011 |
Julian Brown, London GB
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20150191336 | CORKSCREW - A corkscrew ( | 07-09-2015 |
Julian M. Brown, London GB
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20130104105 | TEST DATA SUPPLY CHAIN MANAGER FOR AN INTEGRATED TESTING PLATFORM - A method of supplying test data for test scripts is provided in an integrated testing platform, where the testing platform includes a prioritization and assignment manager configured forward test scripts to a selected testing individual. Each test script is mapped to an input data set if a corresponding input data set is available. Requests for test scripts made to the prioritization and assignment manager are monitored, and if the test script to be supplied in response to the request has a corresponding mapped input data set, the corresponding input data set is retrieved from a database, and the input data set is provided to the test script prior to execution of the test script. | 04-25-2013 |
20130104106 | AUTOMATION CONTROLLER FOR NEXT GENERATION TESTING SYSTEM - An automation controller for next generation testing system includes a database including a plurality of scripts and modules, a business layer component, and an automation component. The automation component includes an automation agent and an automation worker. The business layer component is operable to determine a next script from the plurality of scripts and modules and send the next script to the automation component in response to a get next script request sent by the automation component. The automation agent is operable to send the get next script request to the business layer, receive the next script from the business layer, and send the next script to the automation worker for execution. The automation worker is operable to execute the next script or section thereof, obtain a result, send status updates, send proof of life notifications and the result of execution to the automation agent. | 04-25-2013 |
Matthew J. Brown, London GB
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20140188675 | Expense Calculation and Business Reporting Apparatuses, Methods, and Systems - A system for expense calculation, accrual, allocation, and reconciliation, including an expense calculation module configured to receive transaction data relating to a transaction and to apply at least one charge rule to the transaction data to calculate expense data detailing the expenses expected to be charged in association with the transaction; an accounting control module configured to receive the expense data as an input and to apply at least one accounting rule to the expense data to create enhanced data relating to the transaction; and an invoice reconciliation module configured to receive as inputs the expense data as well as invoice data related to the transaction, and to determine whether the invoice data matches the expense data for the transaction. | 07-03-2014 |
Neil John Brown, London GB
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20150126359 | PROCESS FOR PRODUCING NANOPARTICLES - This invention relates to a process for the preparation of surface-functionalised metal oxide, metal sulphide, metal selenide or metal telluride nanoparticles, a process for the preparation of a composite material comprising such nanoparticles, nanoparticles and a composite material produced thereby, the use of such nanoparticles in catalysis and a catalyst comprising such nanoparticles. | 05-07-2015 |
Neil Jonathan Brown, London GB
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20150052268 | DATA PROCESSING - A data processing apparatus comprises a processor having an internal state dependent upon execution of application program code, the processor being configured to generate display data relating to images to be displayed and to buffer display data relating to a most recent period of execution of a currently executing application. The apparatus includes RAM for storing temporary data relating to a current operational state of program execution. The apparatus also includes a data transfer controller configured to transfer data from the RAM relating to the currently executing application, data relating to a current internal state of the processor and buffered display data to suspend data memory, and to transfer data from the suspend data memory to RAM and to the processor to recreate an execution state of an application at a time the suspend instruction was executed, and to retrieve display data relating to the resumed application. | 02-19-2015 |
Nick Brown, London GB
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20140176565 | COMPUTER IMPLEMENTED METHODS AND SYSTEMS FOR GENERATING VIRTUAL BODY MODELS FOR GARMENT FIT VISUALISATION - Methods for generating and sharing a virtual body model of a person, created with a small number of measurements and a single photograph, combined with one or more images of garments. The model represents a realistic representation of the users body and is used for visualizing photo-realistic fit visualizations of garments, hairstyles, etc. The virtual garments are created from layers based on photographs of real garment from multiple angles. The virtual body model is used in multiple embodiments of manual and automatic garment, make-up, and, hairstyle recommendations, such as, from channels, friends, and fashion entities, and sharable for visualization and comments on looks, for enabling users to buy garments that fit other users, suitable for gifts or similar, and can be used in peer-to-peer online sales where garments can be bought with the knowledge that the seller has a similar body shape and size as the user. | 06-26-2014 |
Robeth Albert Brown, London GB
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20100094409 | IMPROVEMENTS IN AND RELATING TO MEDICAL DEVICES - An endoluminal prosthesis is provided for use in the treatment of a dilation in a body vessel. This dilation might be an abdominal aortic aneurysm or a dilation in a blood vessel wall following a balloon angioplasty procedure. The prosthesis comprises a radially expandable tubular member and a covering provided on the outer surface of the tubular member. The covering comprises first and second layers of material. The first layer comprises an agent that promotes swelling of the covering on exposure of the covering to contact with body fluid, such as blood. The second layer comprises space-filling material. When the prosthesis is delivered into the body vessel the tubular member can automatically expand or be expanded radially. The covering will also swell on the tubular member. This expansion and swelling forces the exterior of the swollen covering into intimate sealing contact with the surrounding inner wall of the vessel. When used in the treatment of an aneurysm this can provide significant advantages in eliminating or reducing primary endoleak. | 04-15-2010 |
Roger Brown, London GB
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20110054801 | Detecting a Chemical Impurity - The invention is a detector ( | 03-03-2011 |
Roger Leslie Brown, London GB
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20080196726 | APPARATUS FOR HYPOXIC TRAINING AND THERAPY - Breathing equipment to mimic the training of athletes at high altitude comprises a mouthpiece connected to a chamber containing a carbon dioxide absorber which is connected to the atmosphere by a tube. In use the air breathed out passes through the carbon dioxide absorber into the conduit where it mixes with atmospheric air and the mixture re-breathed. | 08-21-2008 |
20080264420 | Rotary Valve - A rotary plug valve, especially suitable for providing small pulses of air in which the axis of rotation of the plug is outside the flow path or bore of the valve. The valve opens and closes once in every rotation allowing faster speed motors to be used for the same frequency of air pulses. | 10-30-2008 |
20090196968 | PRESERVATION OF ORGANIC LIQUIDS - A method is provided for treating cooking oil during frying operations, which comprises in situ treatment of the oil with a source of calcium or magnesium combined with silicate such that the calcium or magnesium substantially does not leach into the oil. The filter treatment materials may be cement clinker, OPC, calcium silicate and combinations or mixtures thereof e.g. a combination of white OPC clinker and white OPC. The filter treatment materials may be in the form of a free briquette or block immersed in the oil. In other embodiments a decontaminating or filter cartridge is provided for fitting to a deep oil or fat cooker or a frying basket and comprises a foraminous housing containing filtering or decontaminant material. The cartridge may be used in association with a deep oil or fat fryer having a base formed with a depression defining a cool spot, the cartridge fitting in or on said cool spot. | 08-06-2009 |
20110250330 | PRESERVATION OF ORGANIC LIQUIDS - A method is provided for preserving cooking oil which may be cold or heated or during frying operations, which comprises in situ treatment of the oil withal least one oil-permeable cement body which has been hydraulically hardened from a paste comprising cement clinker and cement e.g. white OPC clinker and white OPC. The invention further comprises cooking oil having therein at least one oil-permeable cement body which has been hydraulically hardened from a paste comprising cement clinker and cement and an oil-permeable cement body for use in the above method. | 10-13-2011 |
20130112607 | HYDRAULICALLY SET CEMENT BODY FOR PRESERVATION OF ORGANIC LIQUIDS - An hydraulically set oil-permeable cement body is provided in the form of a stand-alone block or briquette for preserving cooking oil during deep fat frying, said body. It has substantially no free water or having a low free water content for resisting damage on immersion in cooking oil and initial heating and is enclosed in packaging that resists ingress of water or water vapour The block or briquette consists of >50 wt % of a mixture of milled white OPC clinker and white OPC, optionally silica 1-2 wt % and/or titania (TiO | 05-09-2013 |
20130319416 | RANDOMLY INTERRUPTED BREATHING DEVICE - Apparatus for randomly varying the breathing resistance applied to human and animal subjects to improve their performance. | 12-05-2013 |
Simon G. Brown, London GB
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20110258108 | SYSTEM FOR MATCHING ORDERS FOR FUTURES CONTRACTS WHICH FACILITATE ELECTRONIC TRADING OF OVER THE COUNTER FUTURES CONTRACTS - An electronic trading system and method is disclosed for matching orders for various asset classes including futures contracts and the subsequent settlement and clearance of such contracts. The electronic trading system is configured to be connected to one or more electronic exchanges and is also configured to interface with the existing infrastructure of the front office software of a trading firm, broker or dealer to provide the best fill for traders by enabling electronic trades to be executed both on the exchange and over the counter. In one embodiment of the invention, a local order book is established thereby establishing an independent pool of liquidity of the asset class of interest. | 10-20-2011 |
Simon James Brown, London GB
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20100046846 | IMAGE COMPRESSION AND/OR DECOMPRESSION - A method of image compression in which multiple versions of an image are compressed, each version having a different image resolution, comprises the steps of: for one or more compressed versions of the image: decompressing that compressed version to generate decompressed image data; detecting image differences between a higher resolution version of the image and the decompressed image data; and compressing difference data dependent upon the detected image differences. | 02-25-2010 |
Timothy Brown, London GB
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20100273146 | TB resistance assay - A diagnostic test for detecting multi-drug resistant | 10-28-2010 |