Bradshaw, CA
Allan Bradshaw, Newark, CA US
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20100249702 | POROUS CATHETER BALLOON AND METHOD OF MAKING SAME - A porous balloon or other catheter structure is formed by creating specific size pores for delivering an agent to a body lumen. The pores can be created by passing matter or energy through the surface of the catheter structure, as by a laser or a projectile. In the case of a laser, the catheter structure can be reversed so that the inner surface becomes the outer surface to convert diverging pores into converging pores. In the case of projectiles, a pore size can be achieved by selecting an appropriate size and shaped projectile to obtain the desired characteristic. Alternatively, a material to make the catheter structure can include impurities that can be removed once the catheter structure is set, leaving pores where the material formed around the impurities. | 09-30-2010 |
20110076386 | Stent Fixture and Method for Reducing Coating Defects - A stent fixture for supporting a stent during formation of a coating is provided. | 03-31-2011 |
Curt Bradshaw, San Diego, CA US
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20120301431 | METHODS OF TREATING A DISEASE OR CONDITION ASSOCIATED WITH ABNORMAL ANGIOGENESIS - The present invention provides methods of treating (including preventing) a disease or condition associated with abnormal angiogenesis in a subject include administering a therapeutically effective amount of an AA targeting compound of the invention to the subject. The AA targeting compounds comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody. | 11-29-2012 |
Curt W. Bradshaw, San Diego, CA US
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20090098130 | GLUCAGON-LIKE PROTEIN-1 RECEPTOR (GLP-1R) AGONIST COMPOUNDS - The present invention provides GA targeting compounds which comprise GA targeting agent-linker conjugates linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions. | 04-16-2009 |
20110087010 | ANTI-ANGIOGENIC COMPOUNDS - The present invention provides AA targeting compounds which comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to treat disorders connected to abnormal angiogenesis. | 04-14-2011 |
20140335192 | DELIVERY OF RNA INTERFERING AGENTS - Provided are compositions for the delivery of biomolecules, such as nucleic acids into target cells, and methods of making and using same. The compositions comprise nucleic acid delivery complexes that include a nucleic acid, such as an RNA interfering agent, an RNA neutralization domain, a double stranded RNA binding domain, and a protein transduction domain. | 11-13-2014 |
Curt William Bradshaw, San Diego, CA US
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20100003267 | ANTI-ANGIOGENIC COMPOUNDS - The present invention provides VEGF binding peptides. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules. Various uses of the peptides and compounds are provided, including methods to treat disorders associated with abnormal angiogenesis. | 01-07-2010 |
20120201809 | MULTIFUNCTIONAL ANTIBODY CONJUGATES - The present invention relates to Multifunctional Antibody Conjugates, comprising an antibody or antigen binding portion thereof, comprising at least a fragment of a light chain constant kappa region (CLκ) comprising K | 08-09-2012 |
20120321591 | ANTI-ANGIOGENIC COMPOUNDS - The present invention provides various uses of VEGF binding peptides, including methods to treat disorders associated with abnormal angiogenesis. In addition, the invention provides VEGF peptides conjugated to antibodies alone and in conjunction with other anti-angiogenic molecules | 12-20-2012 |
20150057431 | COMPOSITIONS FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH ABNORMAL ANGIOGENESIS - The present invention provides methods of treating (including preventing) a disease or condition associated with abnormal angiogenesis in a subject include administering a therapeutically effective amount of an AA targeting compound of the invention to the subject. The AA targeting compounds comprise AA targeting agent-linker conjugates which are linked to a combining site of an antibody. | 02-26-2015 |
George L. Bradshaw, Palo Alto, CA US
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20110283902 | Radial Sled Printing Apparatus and Methods - Disclosed are apparatus and methods for implementing a radial sled printer device that substantially simplifies the complexity and reduces system costs and size for radial printing devices, both for devices that print and those that also record and print a label on circular media. | 11-24-2011 |
James Michael Bradshaw, Palo Alto, CA US
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20100285503 | FRET-BASED BINDING ASSAY - The present invention provides for an assay that identifies kinase inhibitors by employing fluorescence resonance energy transfer in a competition binding approach. | 11-11-2010 |
Peter Bradshaw, San Francisco, CA US
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20130201301 | Method and System for Automatic 3-D Image Creation - Disclosed herein are methods, devices, and non-transitory computer readable media that relate to stereoscopic image creation. A camera captures an initial image at an initial position. A target displacement from the initial position is determined for a desired stereoscopic effect, and an instruction is provided that specifies a direction in which to move the camera from the initial position. While the camera is in motion, an estimated displacement from the initial position is calculated. When the estimated displacement corresponds to the target displacement, the camera automatically captures a candidate image. An acceptability analysis is performed to determine whether the candidate image has acceptable image quality and acceptable similarity to the initial image. If the candidate image passes the acceptability analysis, a stereoscopic image is created based on the initial and candidate images. | 08-08-2013 |
20140081933 | Preserving File Metadata During Atomic Save Operations - A method of preserving file metadata associated with an edited file, performed on a client device, includes storing in a log information denoting a plurality of create, delete, and rename operations on one or more files in a file system, and determining when two or more operations denoted in the log, including an operation involving a first file and another operation involving a second file, comprise an atomic save of a respective file, the first file comprising a first version of the respective file, and the second file comprising a second version of the respective file, the first file and second file each having associated metadata. The method further includes associating a subset of the metadata of the first file with the second file, such that at least one of a globally unique file identifier and file access permissions associated with the first file become associated with the second file. | 03-20-2014 |
Peter L. Bradshaw, San Clemente, CA US
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20090076870 | SYSTEMS AND METHODS FOR DATA COLLECTION AT A POINT OF RETURN - Systems and methods are described for collecting data at a merchant's point of return for use in processing a merchandise return transaction that is being requested by a customer. In various embodiments, the data may be collected using a wide variety of data collection technologies and may be used in conjunction with stored data, including data collected from other merchants, by a return authorization system to make a determination whether to accept or deny the requested merchandise return. The data may additionally or alternatively be used to determine whether to issue a warning to the customer about limitations on future return transactions presented by the customer. Examples of data categories that may be collected include, but are not limited to, information about: the merchant, the customer, the requested transaction, the merchandise being returned, one or more receipts, a clerk processing the transaction, and other general applicable information. | 03-19-2009 |
20110087606 | SYSTEMS AND METHODS FOR PROCESSING MERCHANDISE RETURNS - Systems and method for processing merchandise returns are described. In some embodiments, a sales receipt can be received in connection with a requested merchandise return. A receipt identifier can be used to locate sales data associated with the original purchase of the merchandise being returned, and a customer identifier (e.g., a customer loyalty number or a hashed credit card number) can be extracted from the sales data. Customer information, such as prior merchandise return data or prior purchase data, can be retrieved using the extracted customer identifier. The customer information can be used to assess the risk associated with the requested merchandise return for making a determination of whether to accept or deny the return request. Determinations can also be made for whether to provide the customer with a warning or with a coupon in connection with the merchandise return. In some embodiments, multiple customer identifiers can be extracted from a transaction within the sales data and an association can be stored between the multiple extracted customer identifiers. The association can indicate that both customer identifiers relate to a single customer. Then, if a request is later made for customer data associated with a first customer identifier, a response an include customer data for the first customer identifier as well as customer data for other customer identifiers associated with the first customer identifier. | 04-14-2011 |
20120166296 | SYSTEMS AND METHODS FOR DATA COLLECTION AT A POINT OF RETURN - Systems and methods are described for collecting data at a merchant's point of return for use in processing a merchandise return transaction that is being requested by a customer. In various embodiments, the data may be collected using a wide variety of data collection technologies and may be used in conjunction with stored data, including data collected from other merchants, by a return authorization system to make a determination whether to accept or deny the requested merchandise return. The data may additionally or alternatively be used to determine whether to issue a warning to the customer about limitations on future return transactions presented by the customer. Examples of data categories that may be collected include, but are not limited to, information about: the merchant, the customer, the requested transaction, the merchandise being returned, one or more receipts, a clerk processing the transaction, and other general applicable information. | 06-28-2012 |
20130073408 | SYSTEMS AND METHODS FOR DATA COLLECTION AND PROVIDING COUPONS AT A POINT OF RETURN - Systems and methods are described for collecting data at a merchant's point of return for use in processing a merchandise return transaction that is being requested by a customer. In various embodiments, the data may be collected using a wide variety of data collection technologies and may be used in conjunction with stored data, including data collected from other merchants, by a return authorization system to make a determination whether to accept or deny the requested merchandise return. The data may additionally or alternatively be used to determine whether to issue a warning to the customer about limitations on future return transactions presented by the customer. Examples of data categories that may be collected include, but are not limited to, information about: the merchant, the customer, the requested transaction, the merchandise being returned, one or more receipts, a clerk processing the transaction, and other general applicable information. | 03-21-2013 |
20130124296 | SYSTEMS AND METHODS FOR DETERMINING WHETHER TO OFFER A REWARD AT A POINT OF RETURN - Computerized decision-making systems and methods are described for determining whether to provide one or more rewards, such as a coupon or instant discount, to a customer requesting to make a merchandise return at a store, and, if so, to determine the terms of the reward, such as value, expiration date/time and other terms that may be associated with a coupon. The reward determinations may be implemented in conjunction with a system for authorizing the requested merchandise return transaction. Information about the requested return may be used together with data about the customer's past purchase, return transactions, and other customer-related data. In some embodiments, the determinations are based, at least in part, on store-related information and policies. The reward may be printed with a receipt issued to the customer at the point of return and/or may be provided to the customer using a wide variety of other communications technologies. | 05-16-2013 |
20140046750 | SYSTEMS AND METHODS FOR DATA COLLECTION AND PROVIDING COUPONS AT A POINT OF RETURN - Systems and methods are described for collecting data at a merchant's point of return for use in processing a merchandise return transaction that is being requested by a customer. In various embodiments, the data may be collected using a wide variety of data collection technologies and may be used in conjunction with stored data, including data collected from other merchants, by a return authorization system to make a determination whether to accept or deny the requested merchandise return and whether to provide a coupon to the customer. The data may additionally or alternatively be used to determine whether to issue a warning to the customer about limitations on future return transactions presented by the customer. Examples of data categories that may be collected include, but are not limited to, information about: the merchant, the customer, the requested transaction, the merchandise being returned, one or more receipts, a clerk processing the transaction, and other general applicable information. | 02-13-2014 |
20140067504 | SYSTEMS AND METHODS FOR DETERMINING WHETHER TO OFFER A REWARD AT A POINT OF RETURN - Computerized decision-making systems and methods are described for determining whether to provide one or more rewards, such as a coupon or instant discount, to a customer requesting to make a merchandise return at a store, and, if so, to determine the terms of the reward, such as value, expiration date/time and other terms that may be associated with a coupon. The reward determinations may be implemented in conjunction with a system for authorizing the requested merchandise return transaction. Information about the requested return may be used together with data about the customer's past purchase, return transactions, and other customer-related data. In some embodiments, the determinations are based, at least in part, on store-related information and policies. The reward may be printed with a receipt issued to the customer at the point of return and/or may be provided to the customer using a wide variety of other communications technologies. | 03-06-2014 |
20140236702 | SYSTEMS AND METHODS FOR DATA COLLECTION AND PROVIDING COUPONS AT A POINT OF RETURN - Systems and methods are described for collecting data at a merchant's point of return for use in processing a merchandise return transaction that is being requested by a customer. In various embodiments, the data may be collected using a wide variety of data collection technologies and may be used in conjunction with stored data, including data collected from other merchants, by a return authorization system to make a determination whether to accept or deny the requested merchandise return and whether to provide a coupon to the customer. The data may additionally or alternatively be used to determine whether to issue a warning to the customer about limitations on future return transactions presented by the customer. Examples of data categories that may be collected include, but are not limited to, information about: the merchant, the customer, the requested transaction, the merchandise being returned, one or more receipts, a clerk processing the transaction, and other general applicable information. | 08-21-2014 |
20140304044 | RETURN COUPON HOLDER - A return coupon holder is described for holding a return coupon issued in a store in conjunction with a customer's merchandise return transaction. The return coupon holder is preferably sized large enough to discourage the customer from stowing the coupon away, such as in a handbag. Additionally, holders may be of different types that visually or electronically convey information about a category associated with the customer's return transaction. Thus, salespersons may accordingly provide appropriate customer service to the customer. The holder categories may indicate an approximate dollar value of the return transaction, a type of merchandise returned, a return payment method, an assessment of the profitability of the customer, an assessment of the risk of fraud associated with the return transaction, and the like. A computer decision system may select holder type. Some embodiments of the coupon holder are fitted with a device that allow tracing of the customer's movements while still in the store. | 10-09-2014 |
Robert David Bradshaw, San Jose, CA US
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20110214007 | FLEXIBLE FAILOVER POLICIES IN HIGH AVAILABILITY COMPUTING SYSTEMS - A system for implementing a failover policy includes a cluster infrastructure for managing a plurality of nodes, a high availability infrastructure for providing group and cluster membership services, and a high availability script execution component operative to receive a failover script and at least one failover attribute and operative to produce a failover domain. In addition, a method for determining a target node for a failover comprises executing a failover script that produces a failover domain, the failover domain having an ordered list of nodes, receiving a failover attribute and based on the failover attribute and failover domain, selecting a node upon which to locate a resource. | 09-01-2011 |
20140281675 | FLEXIBLE FAILOVER POLICIES IN HIGH AVAILABILITY COMPUTING SYSTEMS - A system for implementing a failover policy includes a cluster infrastructure for managing a plurality of nodes, a high availability infrastructure for providing group and cluster membership services, and a high availability script execution component operative to receive a failover script and at least one failover attribute and operative to produce a failover domain. In addition, a method for determining a target node for a failover comprises executing a failover script that produces a failover domain, the failover domain having an ordered list of nodes, receiving a failover attribute and based on the failover attribute and failover domain, selecting a node upon which to locate a resource. | 09-18-2014 |
Steven E. Bradshaw, West Hills, CA US
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20130176186 | LOW PROFILE CAVITY BACKED LONG SLOT ARRAY ANTENNA WITH INTEGRATED CIRCULATORS - The present invention relates to active electronically scanned array antennas. A thin, low cost design is provided by coupling electromagnetic energy into periodically driven long slots ( | 07-11-2013 |
Steven Edward Bradshaw, West Hills, CA US
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20100203771 | ELECTRICAL INTERCONNECT AND METHOD FOR ELECTRICALLY COUPLING A PLURALITY OF DEVICES - An electrical interconnect system includes a first circuit board that includes at least one via, and a conductor configured to transmit an electrical current therethrough. The conductor includes a first signal contact extending from a conductor first end, and a dielectric cylinder configured to receive the conductor therethrough. The dielectric cylinder includes a first bellows element extending from a first end of the dielectric cylinder that is positioned adjacent to the first signal contact. The first bellows element and the dielectric cylinder are configured to form a substantially continuous outer conductor, wherein the conductor and the first bellows are configured to electrically interface to the via and maintain connection thereto using a biasing force. | 08-12-2010 |