| Patent application number | Description | Published |
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| 20100130405 | BIGLYCAN AND RELATED THERAPEUTICS AND METHODS OF USE - The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders. | 05-27-2010 |
| 20110053854 | TREATMENT OF MUSCULAR DYSTROPHIES AND RELATED DISORDERS - The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. | 03-03-2011 |
| 20110183910 | BIGLYCAN AND RELATED THERAPEUTICS AND METHODS OF USE - The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Examples of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders. | 07-28-2011 |
| 20120245095 | BIGLYCAN AND RELATED THERAPEUTICS AND METHODS OF USE - The invention provides compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. Example of diseases include muscular dystrophies, such as Duchenne's Muscular Dystrophy, Becker's Muscular Dystrophy, neuromuscular disorders and neurological disorders. | 09-27-2012 |
| 20150182589 | TREATMENT OF MUSCULAR DYSTROPHIES AND RELATED DISORDERS - The invention provides, among other aspects, compositions and methods for treating, preventing, and diagnosing diseases or conditions associated with an abnormal level or activity of biglycan; diseases or conditions associated with an abnormal level or activity of collagen VI; disorders associated with an unstable cytoplasmic membrane, due, e.g., to an unstable dystrophin associated protein complex (DAPC); and disorders associated with abnormal synapses or neuromuscular junctions, including those resulting from an abnormal MuSK activation or acetylcholine receptor (AChR) aggregation. | 07-02-2015 |
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| 20090107080 | Weather-resistive barrier for buildings - We form a weather-resistive barrier on a building by applying a compressible latex foam on the gaps between adjacent sheets of construction sheathing and coating | 04-30-2009 |
| 20090107611 | Weather-resistive barrier for buildings - We form a weather-resistive barrier on a building by applying a flexible and compressible latex foam comprising one or more polymer having a glass transition temperature of less than 25° C. on the gaps between adjacent sheets of construction sheathing and coating the sheets and the foam with an aqueous coating composition. The aqueous coating composition is flexible and can comprise the same one or more polymer as the polymer in the foam. | 04-30-2009 |
| 20090139181 | Weather-resistive barrier for buildings - We form a weather-resistive barrier on a building by applying a compressible latex foam on the joints between adjacent sheets of construction sheathing, with the sheets having been coated with an aqueous coating composition. | 06-04-2009 |
| 20110151225 | OPAQUE WET, SEE-THROUGH DRY WEATHER-RESISTIVE BARRIERS AND METHODS FOR MAKING - The present invention provides aqueous self-inspecting wet coatings or films that dry to form translucent to clear weather-resistive barriers on a substrate, preferably a building substrate such as sheathing. The coatings comprise, as a wet film, one or more aqueous emulsion or dispersion polymer that can form a film in use conditions and less than 6% pigment volume concentration (% PVC), of one or more opacifier, one or more extender in amounts up to critical % pigment volume concentration (CPVC), optionally, one or more pigment, and substantially no void, hollow core, or hollow sphere containing pigment. The coatings or films enable one to apply the correct amount of coating to make a weather barrier that dries to a see-through coating or film. | 06-23-2011 |
| 20110168332 | Light touch sealant applicator device - The present invention provides a device for applying a fluid sealant with a light touch, the device comprising a wand with a fluid sealant supply, either as part of the wand or as a separate supply tube, attached to the top of an applicator head via a universal joint, wherein the applicator head has a chamber on its underside which is sufficiently large to enable a constant supply of a fluid sealant to a substrate that is to be sealed, and the applicator head has an edge disposed around its lower periphery adapted to strike the sealant flat. In addition, the present invention provides methods of using the devices to form a seal, e.g. a weather-resistive barrier on a sheathed building structure, by applying a flexible and compressible foam to gaps in the structure. The foam may comprise one or more aqueous polymer having a glass transition temperature of less than 25° C. | 07-14-2011 |
| 20130149456 | OPAQUE WET, SEE-THROUGH WEATHER-RESISTIVE BARRIERS AND METHODS FOR MAKING - The present invention provides aqueous self-inspecting wet coatings or films that dry to form translucent to clear weather-resistive barriers on a substrate, preferably a building substrate such as sheathing. The coatings comprise, as a wet film, one or more aqueous emulsion or dispersion polymer that can form a film in use conditions and less than 6% pigment volume concentration (% PVC), of one or more opacifier, one or more extender in amounts up to critical % pigment volume concentration (CPVC), optionally, one or more pigment, and substantially no void, hollow core, or hollow sphere containing pigment. The coatings or films enable one to apply the correct amount of coating to make a weather barrier that dries to a see-through coating or film. | 06-13-2013 |
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| 20110287935 | HERBICIDAL COMPOSITIONS COMPRISING NAPTALAM - The present invention relates to herbicidal compositions comprising a) a herbicide compound A which is selected from Λ/-1-naphthylphthalamic acid (naptalam), the salts and esters thereof; and b) a herbicide compound B which is selected from b.1 3,6-dichloro-2-methoxybenzoic acid (dicamba), the salts and esters thereof; b.2 quinolinecarboxylic acid herbicides; b.3 pyridinecarboxylic acid herbicides; and b.4 aminocyclopyrachlor, the salts and esters thereof. The present invention also relates to the use of these compositions for controlling undesirable vegetation, in particular in crops, in turf or pasture, in rangeland, in fallow, or in forestry. | 11-24-2011 |
| 20120149577 | Aqueous Suspension Concentrate Formulations Containing Saflufenacil - The present invention relates to aqueous suspension concentrate formulation for plant protection comprising:
| 06-14-2012 |
| 20120157312 | Aqueous Concentrate Formulations Containing Saflufenacil and Glyphosate - The present invention relates to aqueous concentrate formulations for plant protection comprising:
| 06-21-2012 |
| 20120184434 | Low Volatile Amine Salts of Anionic Pesticides - The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt. | 07-19-2012 |
| 20120231954 | LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL AND GLYPHOSATE - The present invention relates to liquid suspension concentrate formulations for plant protection comprising: 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethy)amino]sulfonyl]benzamide in the form of the anhydrate; N-(phosphonomethyl)glycine in the form of its free acid, in the form of the ammonium salt or a substituted ammonium salt or a mixture thereof; at least one diluent selected from: hydrocarbon solvents having a boiling point of at least 100° C.; and —C | 09-13-2012 |
| 20120302444 | LIQUID SUSPENSION CONCENTRATE FORMULATIONS CONTAINING SAFLUFENACIL - The present invention relates to liquid suspension concentrate formulations for plant protection comprising: 2-chloro-5-[3,6-dihydro-3-methyl-2,6-dioxo-4-(trifluoromethyl)-1-(2H)pyrimidinyl]-4-fluoro-N-[[methyl(1-methylethyl)amino]sulfonyl]benzamide in the form of the crystalline anhydrate; at least one diluent selected from: hydrocarbon solvents having a boiling point of at least 100° C.; and C | 11-29-2012 |
| 20130102463 | Herbicidal Compositions - The present invention relates to herbicidal compositions comprising as herbicide A at least one protoporphyrinogen-IX oxidase inhibitor (PPO inhibitor), and at least one light detoxifying compound B, compositions comprising them and their use as herbicides, i.e. for controlling harmful plants, and also a method for controlling unwanted vegetation which comprises allowing a herbicidal effective amount of said herbicidal composition to act on plants, their seed and/or their habitat. | 04-25-2013 |
| 20130225405 | Compositions Containing Identical Polyamine Salts of Mixed Anionic Pesticides - The present invention relates to a composition comprising a first salt, which contains a first anionic pesticide (A1) and a cationic polyamine (B), and a second salt, which contains a second anionic pesticide (A2) and a cationic polyamine (B), wherein both salts contain the same cationic polyamine (B), and wherein the cationic polyamine comprises at least two amino groups. It further relates to a method for preparing said comprising the step of contacting the first salt and the second salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi, which comprises contacting plants, seed, soil or habitat of plants in or on which the harmful insects and/or phytopathogenic fungi are growing or may grow, plants, seed or soil to be protected from attack or infestation by said harmful insects and/or phytopathogenic fungi with an effective amount of said composition. It also relates to a method of controlling undesired vegetation, which comprises allowing a herbicidal effective amount of said composition to act on plants, their habitat or on seed of said plants. Finally, the invention relates to seed comprising said composition. | 08-29-2013 |
| 20140066309 | Method for Enhancing the Performance of a Pesticide with Guanidines - The present invention relates to a method for enhancing the performance of a pesticide comprising the step of contacting an adjuvant and the pesticide, wherein the pesticide is present in a concentration of less than 10 wt % in the resulting composition containing the adjuvant and the pesticide, and wherein the adjuvant contains a guanidine of formula (A) as defined below, and/or a salt thereof. The invention also relates to a composition comprising an auxin-herbicide and said adjuvant; to a use of said adjuvant for enhancing the performance of a pesticide; and to a method of controlling undesired vegetation, which comprises allowing a herbicidal effective amount of said composition to act on plants, their habitat or on seed of said plants. | 03-06-2014 |
| 20140080706 | METHOD OF PREPARING AN AQUEOUS TANK MIX COMPRISING A BASE - The present invention relates to a method of controlling undesired vegetation, and/or phytopathogenic fungi and/or undesired insect attack and/or regulating the growth of plants, which comprises the steps of A) preparing an aqueous tank mix which has a tank mix acidity of at least pH 5.0 comprising contacting a pesticide formulation, water, a base, and optionally an auxiliary; and B) allowing a pesticidal effective amount of said tank mix to act on crops, their habitat, on the undesired vegetation, on the respective pests, and/or on seed of said crops. It also relates to a use of a base for preparing an aqueous tank mix as defined in any of claims | 03-20-2014 |
| 20140171319 | Aqueous Composition Comprising a Pesticide and a Base Selected from an Alkali Salt of Hydrogencarbonate - The invention relates to a liquid aqueous composition, which has a pH value of at least 7.0, comprising a pesticide and a base selected from an alkali salt of hydrogencarbonate; a method for preparing said composition comprising a step of contacting a pesticide and a base selected from an alkali salt of hydrogencarbonate; and a method of combating harmful insects and/or phytopathogenic fungi, which comprises contacting plants, seed, soil or habitat of plants in or on which the harmful insects and/or phytopathogenic fungi are growing or may grow, plants, seed or soil to be protected from attack or infestation by said harmful insects and/or phytopathogenic fungi with an effective amount of the composition. | 06-19-2014 |
| 20150031539 | Tank mix adjuvant comprising an alkyl polyglucoside and a base - The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base. The invention also relates to a use of a tank mix adjuvant for increasing the efficacy of a pesticide, wherein the tank mix adjuvant comprises an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base; to a tank mix adjuvant which comprises an auxiliary, an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base; to a tank mix adjuvant which comprises an auxiliary, an alkyl polyglucoside and a base selected from a carbonate and/or a phosphate, wherein the tank mix adjuvant is present in form in form of a particulate solid, which contains at least 10 wt % of the base; and to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment. | 01-29-2015 |
| 20150051076 | Solid particulate tank mix adjuvant comprising a base selected from a carbonate and/or a phosphate - The present invention relates to q method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of a particulate solid, which contains at least 10 wt % of the base. The invention also relates to a use of a tank mix adjuvant for increasing the efficacy of a pesticide, wherein the tank mix adjuvant comprises a base selected from a carbonate and/or a phosphate, and wherein the tank mix adjuvant is present in form of a particulate solid, which contains at least 10 wt % of the base; to a tank mix adjuvant which comprises an auxiliary and a base selected from a carbonate and/or a phosphate, wherein the tank mix adjuvant is present in form in form of a particulate solid, which contains at least 10 wt % of the base; and to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment. | 02-19-2015 |
| 20150051077 | Liquid or particulate tank mix adjuvant comprising a base selected from a mixture of carbonate and hydrogencarbonate - The present invention relates to q method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base, which contains a mixture of an alkali salt of carbonate and an alkali salt of hydrogencarbonate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base. The invention also relates to a use of a tank mix adjuvant for increasing the efficacy of a pesticide, wherein the tank mix adjuvant comprises a base, which contains a mixture of an alkali salt of carbonate and an alkali salt of hydrogencarbonate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base; to a tank mix adjuvant which comprises an auxiliary and a base, which contains a mixture of an alkali salt of carbonate and an alkali salt of hydrogencarbonate, wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base; to a tank mix adjuvant which comprises an auxiliary and a base, which contains a mixture of an alkali salt of carbonate and an alkali salt of hydrogencarbonate, wherein the tank mix adjuvant is present in form in form of a particulate solid, which contains at least 10 wt % of the base; and to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment. | 02-19-2015 |
| 20150051078 | Glyphosate tank mix adjuvant comprising a base selected from a carbonate and/or a phosphate - The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a glyphosate formulation, water, and a tank mix adjuvant, wherein the tank mix adjuvant comprises a base selected from a carbonate or an alkali salt of a phosphate, and wherein the tank mix adjuvant is present in form of an aqueous liquid, which contains at least 50 g/l of the base, or in form of a particulate solid, which contains at least 10 wt % of the base, wherein the tank mix has a tank mix acidity of at least pH 8.0, and wherein the tankmix contains at least 50 wt % water. The invention also relates to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment. | 02-19-2015 |
| 20150150249 | Drift control agent comprising polypropylene glycol and a triblock polymer - The present invention relates to a method for preparing a tank mix, which comprises the step of contacting a pesticide formulation, water, and a tank mix adjuvant which comprises a polypropylene glycol and a triblock polymer comprising at least one polyethyleneoxide moiety and at least one polypropyleneoxide moiety; to the tank mix adjuvant; to a pesticide formulation comprising the tank mix adjuvant: to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein the tank mix is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment, and to a use of the tank mix adjuvant or reducing the wind drift of a pesticide formulation. | 06-04-2015 |
| 20150173354 | Aqueous Composition Comprising Dicamba and a Drift Control Agent - The present invention relates to an aqueous composition comprising dicamba and a drift control agent; to a method for preparing a tank mix, which comprises the step of contacting water and said composition, and optionally further pesticides; to a method of controlling phytopathogenic fungi and/or undesired vegetation and/or unde-sired insect or mite attack and/or for regulating the growth of plants, wherein the composition is allowed to act on the respective pests, their environment or the plants to be protected from the respective pest, on the soil and/or on undesired plants and/or the crop plants and/or their environment; and finally to a use of the alkoxylate of the formula (I) as defined below for reducing the wind drift of an aqueous composition comprising a pesticide. | 06-25-2015 |
| 20150181865 | Adjuvant comprising a 2-propylheptylamine alkoxylate, sugar-based surfactant, and drift-control agent and/or humectant - The present invention relates to an adjuvant comprising a sugar-based surfactant; a drift control agent and/or a humectant; and an alkoxylate, wherein the alkoxylate is an amine alkoxylate (A) or a quaternized derivative (AQ) of the amine alkoxylate (A) as defined below. It further relates to a method of preparing said adjuvant by contacting | 07-02-2015 |
| 20150210723 | Low Volatile Amine Salts of Anionic Pesticides - The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt. | 07-30-2015 |
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| 20090198221 | APPARATUS AND METHODS FOR DIRECTIONAL DELIVERY OF LASER ENERGY - In some embodiments, without limitation, the invention comprises a catheter having an elongated housing with a channel disposed therein. A laser delivery member is movable and at least partially disposed within the channel. A ramp is disposed within the housing at an angle to its central axis and proximate to its distal end. The ramp is adapted to move the distal end of the laser delivery member outwardly from the central axis of the housing. A guidewire biases the distal end of the laser delivery member generally inwardly toward the central axis of the housing. In some embodiments, without limitation, the offset of the central axis of the tip of the laser delivery member from the central axis of the housing is determined by adjusting the extent to which the laser delivery member travels on the ramp, and disposition of the laser delivery member on the guidewire maintains the offset tip substantially parallel to the central axis of the housing. Thus, in accordance with the invention, the distal end of the laser delivery member may be biased in a desired direction or offset, permitting ablation of an area larger than the area of the distal end of the catheter. | 08-06-2009 |
| 20100191315 | INNER AND OUTER TELESCOPING CATHETER DELIVERY SYSTEM AND METHOD - A method of delivering a payload to a destination vessel branching from a coronary sinus of a patient's heart. The method comprises inserting a catheter assembly into a right atrium of the patient's heart. The catheter assembly comprises an outer catheter and an inner catheter movably disposed within the open lumen of the outer catheter. The inner and outer catheters are operable to be rotated and translated relative to one another such that the distal end of the outer catheter can assume a selectable plurality of shapes appropriate for accessing the coronary sinus. The method further comprises locating and cannulating the patient's coronary sinus by adjusting a relative orientation or longitudinal position of the inner catheter relative to the outer catheter, longitudinally sliding the outer catheter over the distal end of the inner catheter to deep seat the outer catheter within the patient's coronary sinus, and delivering a payload to the destination vessel through the outer catheter or the inner catheter. | 07-29-2010 |
| 20110009750 | CARDIOVASCULAR IMAGING SYSTEM - Embodiments of the present invention include a laser catheter that includes a catheter body, a light guide, and a distal tip that extends beyond the exit aperture of the light guide. In some embodiments, an imaging device is disposed on the distal tip such that the imaging device is distal relative to the exit aperture of the light guide. In some embodiments, the imaging device can be gated to record images during and/or slightly beyond periods when the laser catheter is not activated. | 01-13-2011 |
| 20110208207 | Endocardial lead removing apparatus - The invention provides an apparatus having a tubular member for receiving an endocardial lead implanted within a patient's body. Disposed generally at a distal end of the tubular member is at least one blade or cutting surface. An adjustment mechanism moves the blade between retracted and extended positions to engage the cutting surface with the endocardial lead to cut the lead. Once severed, the cut portion of the lead remains within an inner channel of the tubular member and the apparatus and cut portion of the lead are removed from within the patient. Various embodiments include the blade pivotally connected to the distal end of the tubular member and activated by a wire adjustment mechanism. Others include a metallic wire for slicing through the lead. Still others include a pneumatically actuated adjustment mechanism that inflates to move the blade and engage the cutting surface with the lead. | 08-25-2011 |
| 20120095479 | Endocardial Lead Removing Apparatus - The invention provides an apparatus having a tubular member for receiving an endocardial lead implanted within a patient's body. Disposed generally at a distal end of the tubular member is at least one blade or cutting surface. An adjustment mechanism moves the blade between retracted and extended positions to engage the cutting surface with the endocardial lead to cut the lead. Once severed, the cut portion of the lead remains within an inner channel of the tubular member and the apparatus and cut portion of the lead are removed from within the patient. Various embodiments include the blade pivotally connected to the distal end of the tubular member and activated by a wire adjustment mechanism. Others include a metallic wire for slicing through the lead. Still others include a pneumatically actuated adjustment mechanism that inflates to move the blade and engage the cutting surface with the lead. | 04-19-2012 |
| 20130184598 | INNER AND OUTER TELESCOPING CATHETER DELIVERY SYSTEM - A catheter assembly employs an outer catheter with a pre-formed distal end and an open lumen. An inner catheter having an open lumen and a pre-formed distal end is movably disposed within the outer catheter. Relative rotation and extension of the inner and outer catheters provides the distal end of the catheter assembly with an adjustable range of two- and three-dimensional shapes. The inner catheter can include sections of varying stiffness, such that extension of the inner catheter within the outer catheter modifies the shape of the outer catheter's pre-formed distal end. One or both of the outer and inner catheters includes an occlusion balloon attached to the distal end thereof. The adjustable shaping of the catheter assembly's distal tip provides an improved system for locating and cannulating cardiac venous structures, particularly the coronary sinus via the right atrium. | 07-18-2013 |
| 20140081252 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
| 20140081303 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
| 20140081304 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
| 20140081306 | TISSUE SLITTING METHODS AND SYSTEMS - Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures. | 03-20-2014 |
| 20140371718 | REENTRY CATHETHER AND METHOD THEREOF - Embodiments of the invention are directed towards a rapid exchange catheter configured for insertion into a subintimal space and crossing an occlusion in a subintimal space. The catheter includes a proximal end, a distal end, a first lumen configured to receive a first wire, the first lumen extending longitudinally through a least a lateral port of the catheter, and a second lumen having at least a portion distal of the lateral port and extending through at least the distal end of the catheter. The catheter also includes an exchange port arranged on a exterior portion of the catheter configured to the receive a second wire and second rapid exchange port in communication with the second lumen. Moreover, other embodiments of the invention are directed towards methods for using the rapid exchange catheter to cross an obstruction in a vessel, e.g., a total or partial occlusion, in a subintimal space. | 12-18-2014 |
