Bourne, US

Andrew Bourne, Bothell, WA US

Patent application number	Description	Published
20100001136	AIRCRAFT DOOR AND METHOD FOR USING THE SAME - An external door for use in accessing a cargo area of an aircraft fuselage. The door includes a locking system, a latching system, a lock monitoring system, an uplock used to secure the door in an open position, and an actuating system that assists in at least one of opening and closing the door. The locking system works by interfering with the movement of the latching system components. The locking system includes a monitoring device that prevents the aircraft from being pressurized in case of a malfunction in the locking system. The latching system includes a handle locking system that prevents operation of the latch handle by accident or by ground loading or flight forces. The systems of the door are preferably manually operated, and utilize rigid members.	01-07-2010

Benjamin C. Bourne, Davis, CA US

Patent application number	Description	Published
20130000356	GLASS BENDING METHOD AND APPARATUS - A sag-bending glass mold for creating a partial parabolic-curved glass sheet is disclosed. The glass mold comprises a glass-support surface having a cross-sectional profile of varying height. The cross-sectional profile has a first portion with profile of a non-parabolic, linear-square root composite shape. A method for forming a partial parabolic glass sheet is also disclosed. The method comprises positioning a planar glass sheet on a sag-bending mold having a linear-square root composite shape and deforming the glass sheet to follow the linear-square root composite shape of the sag-bending mold.	01-03-2013

Chris Bourne, Draper, UT US

Patent application number	Description	Published
20160051718	Gel Can Air Freshener with Dual Scent - An air freshener comprises a container divided into separate and discrete reservoirs separated by an inner wall. A cap is disposed on the container and covers the reservoirs. First and second different fragrant materials are each disposed in a different one of the separate and discrete reservoirs so that the first and second different fragrant materials are separate and discrete with respect to one another in the container. The first and second different fragrant materials have different fragrances combinable in a synergistic manner. The first and second different fragrant materials each comprise a water based gel. One of the fragrant materials can comprise a neutralizing agent.	02-25-2016

Chris Bourne, Standsbury Park, UT US

Patent application number	Description	Published
20150108239	Air Freshener with Porous Membrane with Leak Pad and Adjustable Opening - An air freshener comprises a scent capsule carried by a housing. The scent capsule comprises a reservoir containing a fragrant material, and with an opening to a cavity therein and covered by a permeable membrane through which a fragrance can permeate, and a releasable seal sealed over the opening and the permeable membrane to resist fragrance release until removed. An absorptive pad is disposed behind the releasable seal between the scent capsule and the housing, and is capable of absorbing the fragrant material that permeates through the permeable membrane.	04-23-2015
20150108243	Gel Can Air Freshener with Dual Scent - An air freshener comprises a container divided into an inner cylindrical reservoir and an outer annular reservoir with at least two different fragrant materials with different fragrances. A cap is carried by the container and covers the reservoirs. A sleeve extends from the cap into the container between the reservoirs. The cap is movable axially with respect to the container between a raised position in which the at least two different fragrances are released, and a closed position in which the cap covers the container to resist release of the at least two different fragrances.	04-23-2015

Christina Renee Bourne, Stillwater, OK US

Patent application number	Description	Published
20150065509	HIGHLY 6-SUBSTITUTED -2,4-DIAMINOPYRIMIDINES AS INHIBITORS OF ANTHRAX - 2,4-diaminopyrimidine compounds of generic Formula 1, where R and R′ may be the same or different and are independently selected from: C	03-05-2015

Christopher Bourne, Draper, UT US

Patent application number	Description	Published
20150374873	VENT STICK AIR FRESHENER WITH DUAL ACTION BODIES AND AIR FLOW TUNNEL - A vent stick air freshener has a pair of vent rods extending rearwardly from an annular head with a hollow therein, an open front end and an open rear end defining an air tunnel. At least one body is carried by at least one of the pair of vent rods. An insert is at least partially received in the hollow of the annular head. A space is defined between the insert and the annular head. The at least one body or the insert or both has a desired scent material interspersed therein and diffusible out over time.	12-31-2015

Christopher Bourne, Stans Bury Park, UT US

Patent application number	Description	Published
20100271287	Dual-display transportable media cart - The claimed systems relate generally to a cart having repositionable displays, and more particularly to a mobile cart having a frame on which is affixed two or more fixtures having a display mount, the fixtures providing for the movement of displays affixed thereto in a position for viewing, and another position for cart movement, such as movement between rooms through a doorway or an elevator. Also disclosed are particular articulating arms for such fixtures, mounted to one or more posts, some having one or more pivotable arms allowing for repositioning of displays relative to a cart. Detailed information on various example embodiments of the inventions are provided in the Detailed Description below, and the inventions are defined by the appended claims.	10-28-2010

David A. Bourne, San Francisco, CA US

Patent application number	Description	Published
20140096126	UPDATING CONTROL SOFTWARE ON A NETWORK-CONNECTED HVAC CONTROLLER - Apparatus, systems, methods, and computer program products are disclosed for providing software updates to client devices. A client device (such as a thermostat) executes software to perform one or more functionalities of the device. Upon receiving an indicating that a software update is available, the device waits to download the software update until pre-download conditions are satisfied. Once the software update is downloaded, the device then waits to install the software update until pre-install conditions are satisfied. If the software update is non-critical and received during an initial installation of the device, the software update may not be installed until after installation of the device is complete. If the device is a thermostat, the device may delay installation of the software update until a controlled HVAC system in inactive. Control of the HVAC system may be disabled during installation of the software update.	04-03-2014
20150074658	UPDATING CONTROL SOFTWARE ON A NETWORK-CONNECTED HVAC CONTROLLER - Apparatus, systems, methods, and computer program products are disclosed for providing software updates to client devices. A client device (such as a thermostat) executes software to perform one or more functionalities of the device. Upon receiving an indicating that a software update is available, the device waits to download the software update until pre-download conditions are satisfied. Once the software update is downloaded, the device then waits to install the software update until pre-install conditions are satisfied. If the software update is non-critical and received during an initial installation of the device, the software update may not be installed until after installation of the device is complete. If the device is a thermostat, the device may delay installation of the software update until a controlled HVAC system in inactive. Control of the HVAC system may be disabled during installation of the software update.	03-12-2015

Doug Bourne, Campbell, CA US

Patent application number	Description	Published
20140276366	MULTIPLE IMPACT MICROPROJECTION APPLICATORS AND METHODS OF USE - Applicators for a microprojection array capable of multiple impacts and methods of using the applicators are described.	09-18-2014
20140276580	MICROPROJECTION APPLICATORS AND METHODS OF USE - Applicators for a microprojection array and methods of using the applicators are described.	09-18-2014
20140276589	MICROARRAY FOR DELIVERY OF THERAPEUTIC AGENT AND METHODS OF USE - Microstructure arrays and methods for using and manufacturing the arrays are described.	09-18-2014

Douglas Joseph Scott Bourne, Mountain View, CA US

Patent application number	Description	Published
20140232267	Workspace lighting system - A modular lighting system for lighting a work area is disclosed. The system includes a power supply with power outlets for powering LED fixtures. The power supply preferably operates at or below a fixed power output level, such as to illuminate the work area using less than 0.2 Watts per square foot of energy. The lighting system also includes an occupancy sensor and/or a light level sensor for controlling lighting levels in the work area in response to detection of a person, ambient light levels and/or a combination thereof. The lighting system can also include computer unit with a micro-processor and a memory unit for running software or firmware the executes lighting programs, stores light usage histories and/or provides system reports to a remote computer by a wireless means and/or over a computer network.	08-21-2014

Douglas Joseph Scott Bourne, Campbell, CA US

Patent application number	Description	Published
20110276027	APPLICATORS FOR MICRONEEDLES - An applicator for a microprojection array is described. In one embodiment, the applicator comprises an energy-storing element. Application of force causes the compressed energy-storing element to extend or transition from first and second configurations, releasing stored energy to deploy a holding member in the application which is configured to hold an array of microprojections. In another embodiment, the applicator comprises an energy storing element with two stable configurations, a first stable configuration and second stable configuration. Application of force causes the energy-storing element to transition from the higher energy first stable configuration to the lower energy second stable configuration, releasing the difference in energies of the two states to deploy a holding member in the application which is configured to hold an array of microprojections.	11-10-2011
20110292640	Workspace lighting system - A modular lighting system for lighting a work area is disclosed. The system includes a power supply with power outlets for powering LED fixtures. The power supply preferably operates at or below a fixed power output level, such as to illuminate the work area using less than 0.2 Watts per square foot of energy. The lighting system also includes an occupancy sensor and/or a light level sensor for controlling lighting levels in the work area in response to detection of a person, ambient light levels and/or a combination thereof. The lighting system can also include computer unit with a micro-processor and a memory unit for running software or firmware the executes lighting programs, stores light usage histories and/or provides system reports to a remote computer by a wireless means and/or over a computer network.	12-01-2011
20150126856	ATHERECTOMY CATHETER DRIVE ASSEMBLIES - A drive assembly for driving an imaging catheter has a rotatable fiber and a rotatable drive shaft. The drive assembly includes a fiber optic rotating junction and a motor configured to rotate the rotatable portion of the fiber optic rotating junction. In some embodiments, the drive assembly includes a sensor configured to detect a rotational position of the fiber optic rotating junction and a processor configured to obtain the detected rotational position and stop the motor only when the fiber optic rotating junction is in a predetermined rotational position. In some embodiments, the motor includes a hollow shaft through which at least a portion of the fiber optic rotating junction extends.	05-07-2015

Frederick L. Bourne, Litchfield, CT US

Patent application number	Description	Published
20140150446	BATTERY CURRENT REGULATION - Embodiments are directed to an engine of an aircraft, a starter generator configured to receive power to cause the engine to start and to provide electrical power to at least one load, and a battery system comprising: a battery, and at least one of a controller and a regulator configured to limit an in-rush current to the battery following the starting of the engine.	06-05-2014
20150028597	SWASHPLATELESS COAXIAL ROTARY WING AIRCRAFT - A main rotor system of an aircraft is provided including a first rotor coupled to a transmission and configured to rotate about an axis in a first direction. A second rotor is similarly coupled to the transmission and is configured to rotate about the axis in a second direction. At least the first rotor includes an individual blade control system (IBCS) configured to adjust a pitch of each of a plurality of blade of the first rotor independently. At least one slip ring is configured to transmit electrical power and/or a control signal to the at least one IBCS.	01-29-2015
20150225089	ENGINE ELECTRICAL LOAD SHED CONTROL - A method of engine electrical load shed control includes receiving an accessory load indicator corresponding to an accessory load of an engine. A request for acceleration of the engine is detected. One or more electrical buses are depowered based on the accessory load indicator exceeding a shedding threshold and detection of the request for acceleration of the engine.	08-13-2015

George Bourne, Southborough, MA US

Patent application number	Description	Published
20090156893	FLATTENED TUBULAR MESH SLING AND RELATED METHODS - The invention generally relates to surgically implantable supportive slings. More specifically, in various embodiments, the invention is directed to multilayer mesh slings formed from a tubular mesh material.	06-18-2009
20110054312	Reinforced Venous Access Catheter - A catheter for medical procedures comprises a shaft portion having a distal end insertable into a body lumen, the shaft portion having a wall defining a working lumen extending therewithin and a first strengthening element coupled to the wall to increase a burst pressure of the shaft portion, wherein the first strengthening element cooperates with a base material of the wall to define a flexible region of the shaft portion allowing the shaft portion to be atraumatically inserted into the body lumen.	03-03-2011
20110064774	BULKING AGENT - The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, aneurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents.	03-17-2011
20130025781	FLATTENED TUBULAR MESH SLING AND RELATED METHODS - The invention generally relates to surgically implantable supportive slings. More specifically, in various embodiments, the invention is directed to multilayer mesh slings formed from a tubular mesh material.	01-31-2013
20130190720	BULKING AGENTS - The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, aneurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents.	07-25-2013
20140072636	BULKING AGENTS - The invention relates to bulking agents and apparatus and methods for using the disclosed bulking agents. The bulking agents can be used to treat such conditions as urinary and fecal incontinence, gastro-esophageal reflux, ancurismal blockages, and cosmetic deformities. The invention also relates to an injection method that reduces the injection pressure required to place the bulking agents.	03-13-2014

George Bourne, Southboro, MA US

Patent application number	Description	Published
20110054448	MEDICAL DEVICE CONTAINING CATHETER ANCHORING FEATURE - An indwelling drainage catheter is disclosed that is configured to include spiral, helical or radial geometry on the external surface that allows the catheter to be introduced and locked into the anatomy via threading, linear indexing or similar action.	03-03-2011
20120265173	MEDICAL DEVICE CONTAINING CATHETER ANCHORING FEATURE - An indwelling drainage catheter is disclosed that is configured to include spiral, helical or radial geometry on the external surface that allows the catheter to be introduced and locked into the anatomy via threading, linear indexing or similar action.	10-18-2012

George Bourne, Boston, MA US

Patent application number	Description	Published
20140058332	IMPLANTABLE MEDICAL DEVICE FOR IMPROVED PLACEMENT IN THE BODY - An implantable port includes a bottom portion having a needle-penetrable region running continuously along a majority of a perimeter of the implantable port. A method for customized suturing of an implantable port also includes creating a port pocket, and advancing a suture needle through the needle-penetrable region. The needle-penetrable region could be a self-sealing elastomer, such as silicone. The method could include the step of determining suture locations after the port pocket is created.	02-27-2014
20150209515	Power Injector Device and Method of Use - Automated injection system disclosed in this application advantageously provides physicians with a simplified interface for selecting fluid sources, such as saline, contrast, or a mixture of both, to inject at high pressures. The injector system may comprise a multi-use subassembly, a single-use subassembly, a fitting to fluidly connect the multi-use and single-use subassemblies, a hand held controller, a user interface, and an injector housing.	07-30-2015
20160001055	Implanatable Medical Device for Improved Placement and Adherence in the Body - A medical device comprises a flexible member that can be adhesively attached to a housing of the medical device, allowing implantation of the medical device into a body through an incision of reduced size. The flexible member can be attached to the housing either before or after implantation into the body. The flexible member comprises suture locations, including a permeable membrane or a suture hole, for suturing the medical device to tissue of the body. The suture holes can be filled with a substance penetrable by a suture needle, to minimize tissue ingrowth before or after suturing.	01-07-2016

Grayson Hugh Bourne, Golden Beach, FL US

Patent application number	Description	Published
20120277068	ERGOMETER FOR SKI TRAINING - A ski-simulation assembly includes a vertical member with a first portion coupled to a base and a second portion extending upwardly from the base, a first cable portion slidably engaged with the vertical member at the second portion of the vertical member, a second cable portion slidably engaged with the vertical member at the second portion of the vertical member, and a resistance-producing assembly physically coupled to the first cable portion and the second cable portion, where the resistance-producing assembly operable to apply a selective resistance to the first cable portion independent of movement of the second cable portion and apply a selective resistance to the second cable portion independent of movement of the first cable portion.	11-01-2012
20140221169	STAND-UP PADDLEBOARD EXERCISE ASSEMBLY - A stand-up paddleboard exercise assembly having a paddle member with a proximal end and a distal end and a support assembly with an upper support surface with a left edge and a right edge, a frame separating the upper support surface from a ground surface, a following arm having a proximal end coupled to the support assembly, a distal end opposite the proximal end, and operable to rotate from a first position where the distal end is closer to the left edge of the upper support surface to a second position where the distal end is closer to the right edge of the upper support surface, the support assembly also having a resistance-producing assembly physically coupled, through a cable, to the distal end of the paddle member, the cable being slidably coupled to the following arm.	08-07-2014

Jeffrey Thomas Bourne, Harrisonburg, VA US

Patent application number	Description	Published
20110191136	SYSTEM AND METHOD FOR WEB-BASED SPORTS EVENT SCHEDULING - A system and methods are provided for communication between entities that need to coordinate on scheduling events. Communication between schedulers, such as coaches, athletic administrators or organization administrators who may be in charge of a multiplicity of sports or activities at institutions, such as colleges or universities, who need to connect and communicate on a particular task. These tasks may include scheduling of events such as sports competitions or other events or activities in which there may be shared or common interests or a shared network of users, players or participants. Search by criteria to find matching potential opponents for scheduling events is also provided. Automatic schedule updates are maintained, typically in a logically centralized database, facilitated by a messaging system to facilitate ease of scheduling.	08-04-2011

John M. Bourne, Tustin, CA US

Patent application number	Description	Published
20090032123	Check Valve - A check valve having a piston-like ball or stopper a pre-determined distance from the valve seat so that the ball or stopper seats against the valve seat only under backflow pressure.	02-05-2009
20100076471	Spring-Less Check Valve For A Handpiece - A hand piece for a surgical instrument is provided. The handpiece has an inlet, a chamber (with upstream and downstream portions), a flow control member, a pulse engine, and an outlet. The inlet communicates with the upstream portion of the chamber. The downstream portion of the chamber communicates with the engine. The engine communicates with the outlet. In a closed position of the member, flow from the inlet moves the member to the open position thereby allowing flow through the flow path. In the open position, pulses from the engine move the member to the closed position before pulses from the pulse engine can flow through the flow path, thereby preventing flow through the flow path.	03-25-2010
20130030407	Fluidic components, systems, and methods for use in ophthalmic surgeries - Fluidic components, systems, and methods for use in ophthalmic surgeries are disclosed. In some embodiments, a fluidics cassette for use with an ophthalmic surgical console system is provided. The fluidics cassette includes a housing, a fluid passageway extending through the housing, a membrane positioned in fluid communication with the fluid passageway such that a fluid passing through the fluid passageway contacts the membrane, and an opening extending at least partially through the housing such that the opening is in communication with the membrane and is configured to be coupled to a vacuum source. When the vacuum source is coupled to the opening, fluid passing through the passageway is subjected to the vacuum generated by the vacuum source through the membrane to remove dissolved gasses from the fluid.	01-31-2013
20130046228	Stacked Multi-Disk Ophthalmic Pump - The present disclosure relates to a stacked multi-disk pump for the pumping of ocular fluid and/or tissue during ophthalmic surgery. The stacked multi-disk pump includes an inlet port, a stacked multi-disk assembly, a fluid chamber, a central hub, a motor, and an outlet port. The motor and the hub induce the multi-disk assembly to rotate. As the multi-disk assembly rotates, the fluid is propelled into the inlet port, progresses axially, circumferentially, and radially through the stacked multi-disk assembly, and flows out the outlet port. The pump may be incorporated, for example, into the handpiece of an ophthalmic surgical instrument or a surgical console.	02-21-2013

John Morgan Bourne, Tustin, CA US

Patent application number	Description	Published
20100324476	FLUIDICS CONTROL VIA WIRELESS TELEMETRY - In various embodiments, a pressure sensor may be configured to detect pressure information associated with pressure in an eye during an ophthalmic surgical procedure. The pressure information may be wirelessly communicated, through a transmitter coupled to the pressure sensor, to a receiver communicatively coupled to a surgical console. The receiver may provide the received pressure information to the surgical console to use in controlling pressure at a surgical site during the surgical procedure. For example, controlling the pressure may include maintaining a desired IOL pressure level within the surgical site at the eye. In some embodiments, the pressure sensor may include a strain gage coupled to a contact lens or a sleeve of an ocular surgical handpiece. Other pressure sensor configurations are also contemplated.	12-23-2010
20110144632	Flooded Liquefaction Hand Piece Engine - In various embodiments, an ophthalmic handpiece may include a handpiece body with a pulse chamber and flooded engine compartment configured to receive fluid from a surgical console through a fluid inlet port. Heated pulses from the pulse chamber and cooler fluid from the flooded engine compartment may flow through a tip into the eye. In some embodiments, the tip may be a dual lumen tip that keeps the flows from the pulse chamber and flooded engine compartment separate until they exit the tip. In some embodiments, a tip, coupled to a merging chamber where the flows may merge prior to the tip, may be a single lumen tip that directs the heated pulses and irrigation fluid simultaneously to a lens to liquefy the lens for removal from the eye.	06-16-2011

John Morgan Bourne, Irvine, CA US

Patent application number	Description	Published
20140163454	VACUUM CONTROL METHOD FOR SURGICAL HAND PIECE - A surgical hand piece is described that maintains a vacuum pressure within the hand piece at a selected level. A check valve is provided substantially near an inlet of an integrated aspirating pump. The check valve opens to introduce fluid into the hand piece to maintain the vacuum pressure within the hand piece at or above the selected level so as to prevent or substantially reduce post-occlusion flow.	06-12-2014
20140271251	SYSTEMS AND METHODS FOR OCULAR SURGERY - Ocular surgery may be performed by a variety of systems, processes, and techniques. In certain implementations, a system and a process for ocular surgery may include the ability to draw ocular fluid into a channel of a hand-held pump system and separate the fluid into multiple compressible channels to create multiple flows. The system and the process may also include the ability to peristaltically pump the fluid through the compressible channels.	09-18-2014
20150125328	OPHTHALMIC LUBRICATION SYSTEM AND ASSOCIATED APPARATUS, SYSTEMS, AND METHODS - Devices, systems, and methods including a lubricating solution bath for a pump integrated into an ophthalmic surgical hand piece are provided. In some embodiments, an ophthalmic pump system includes a housing defining a cavity. The system includes a rotating element positioned within the cavity of the housing. The system includes a flexible tubular structure positioned within the housing adjacent to the rotating element such that rotation of the rotation element urges a fluid through the flexible tubular structure. The system includes a lubricating solution positioned within the cavity around the rotating element and at least a portion of the flexible tubular structure.	05-07-2015
20150157501	Devices, Systems, and Methods for Tip Vacuum Control During Aspiration - Disclosed herein is an apparatus for insertion in an eye of a patient for aspirating material from the eye in the treatment of an ocular condition, the apparatus comprising a needle disposed at a distal end of the apparatus, an aspiration channel extending from a distal aperture of the needle to a proximal end of the apparatus, and an irrigation sleeve coaxially disposed about the needle. The aspiration channel comprises a proximal portion having a first diameter, a bypass portion having a second diameter and at least one bypass port, and a distal portion having a third diameter. The second diameter is larger than the first diameter. The irrigation sleeve and the needle form an annular irrigation passageway therebetween. The bypass port is shaped and configured to establish fluid communication between the irrigation passageway and the aspiration channel.	06-11-2015
20150297405	HYDRAULIC PUMP FOR OPHTHALMIC SURGERY - Apparatuses, systems, and method for hydraulic pumps are disclosed. Particularly, hydraulic pumps for ophthalmic surgical procedures are disclosed. Hydraulic pumps within the scope of the disclosure may include an aspiration pump. An example aspiration pump may include first and second hydraulic cylinders and a plurality of one-way valves that are operable to permit fluid flow into a first part of a hydraulic cylinder responsive to movement of a piston within the hydraulic cylinder in a first direction and operable to permit fluid to flow out of the hydraulic cylinder responsive to movement of the piston in a second direction opposite the first direction. The aspiration pump may be attached to a housing of a hand piece, or a portion of the aspiration pump may be received into the housing of the hand piece.	10-22-2015

Jonathan W. Bourne, Fairport, NY US

Patent application number	Description	Published
20130310539	Glycation Cross-link Breakers to Increase Resistance to Enzymatic Degradation - The present invention relates to a method to treat a grafts, implant, scaffold, and constructs, including allografts, xenografts, autografts, and prosthetics comprising collagen, with an inhibitor of collagen cross-links and/or advanced glycation endproducts (AGE), in order to alleviate the mechanical weakness induced by the cross-links The invention also provides for kits for use in the operating theater during autograft, allograft or xenograft procedures, or for preparing allograft, xenografts or prosthetics that have not been already treated prior to packaging. The kit comprises a first agent or agents that inhibit collagen cross-links and/or advanced glycation endproducts, instructions for use, optionally a wash or rinse agent, and a device for containing the graft and first agent.	11-21-2013

Jonathan William Bourne, Fairport, NY US

Patent application number	Description	Published
20160083425	Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Allosteric Binding Ligands To Modulate Serum Low Density Lipoprotein (LDL) Levels - This invention is related to the field of hypercholesterolemia. In particular, the invention provides compositions and methods to modulate circulating levels of low density lipoproteins by altering the conformation of the protein PCSK9 using synthetic ligands and/or synthetic ligand derivative sequences of 3-8 amino acids ranging between 350-2,000 Da. Altering the conformation of PCSK9 affects the interaction between PCSK9 and an endogenous low density lipoprotein receptor, and can lead to reduced or increased levels of circulating LDL-cholesterol. High LDL-cholesterol levels are associated with increased risk for heart disease. Low LDL-cholesterol levels may be problematic in other conditions, such as liver dysfunction; thus, there is also utility for ligands which can raise LDL levels.	03-24-2016

Joshua Slocum Bourne, Bethesda, MD US

Patent application number	Description	Published
20110004850	METHODS AND APPARATUS FOR DETERMINING WEBSITE VALIDITY - In one embodiment, a computer-readable medium comprises code representing instructions to cause a processor to receive a fetch response based on a webpage address that may be associated with a webpage. The code can additionally represent instructions to calculate a webpage validity score for the webpage. The validity score can be based on at least one of content or metadata associated with the webpage. The code can also represent instructions to cause the processor to store a thumbnail image of the webpage, along with an indicator of the validity score. The validity indicator can be based on the webpage validity score and a threshold value.	01-06-2011

Julian J. Bourne, Weston, MA US

Patent application number	Description	Published
20090005040	Method and computer system for matching mobile device users for business and social networking - A business or social networking method is operative in a server. The method enables mobile device users to meet one another, on a permission basis. The determination of whether a given pair of mobile device users are introduced depends on whether the server determines they are in intellectual or “cognitive” proximity, which is typically a function of one or more factors, such as: each user's reciprocal networking objective, the nature of the industry in which the user works, the user's level within the management hierarchy of his or her company, any specialty function the individual may possess, and so on. Individuals who are matched in one or more of such attributes to a given degree or threshold are said to be in intellectual proximity. According to the invention, when given mobile devices users are within physical proximity of one another during an overlapping time window, the server determines whether the users are also within a given intellectual proximity. If so, and if both users have opted to receive new introductions, the server issues a mutual collaboration opportunity message to each of the mobile device users to determine whether they desire to be introduced to one another. Preferably, the mutual collaboration opportunity message masks personally identifying information. If the mobile device users agree to be introduced, the server establishes a direct private messaging session between them. In an alternative embodiment, a mobile device user initiates a contact by performing a networking search query that identifies one or more prospects who can then be contacted by the mobile device user asynchronously.	01-01-2009
20090192702	Situation-aware personal information management for a mobile device - A technique for providing a mobile device user with a “when to leave” alarm on his or her mobile device. The user has scheduled an appointment at a given time and location in the user's personal information manager (PIM) executing on the mobile device. A representative PIM is a calendar on the mobile device. The “when to leave” alarm is provided to the end user in the form of a display widget (or “countdown alarm”) that automatically activates a given time (e.g., 30 minutes) before a latest departure time for an event in the user's PIM.	07-30-2009
20130231858	Identifying future location and providing path crossing indications - A user of a mobile device may use the technique to obtain future location-based situation awareness, e.g., a future location route displayed on the user's mobile device. That future location route comprises the user's future locations through time and space, e.g., a set of planned meetings at successive locations in a geographic area. A service that provides the user's mobile device with the future location route may also alert the user of potential threats to the user's planned activities, such as a restaurant being over-booked. On a permission basis, the user's mobile device may also receive a future location route for at least one other person associated with the user in a social network. The other person's future location route may be overlaid on the user's route so that one or both individuals receive advance notifications of their potential to have their respective paths “crossing” during a future time period.	09-05-2013
20140039787	Situation-aware personal information management for a mobile device - A technique for providing a mobile device user with a “when to leave” alarm on his or her mobile device. The user has scheduled an appointment at a given time and location in the user's personal information manager (PIM) executing on the mobile device. A representative PIM is a calendar on the mobile device. The “when to leave” alarm is provided to the end user in the form of a display widget (or “countdown alarm”) that automatically activates a given time (e.g., 30 minutes) before a latest departure time for an event in the user's PIM.	02-06-2014
20140067434	Methods and Systems for Providing Risk Profile Analytics - A risk profile system determines a risk profile of a driver of a vehicle using improved driver metrics. Driver characteristics of a driver are determined as the driver encounters one or more locations that have an associated weighted accident history. The determined driver characteristics of the driver are compared to a normal distribution curve of driving characteristic data at one or more of the locations encountered by the driver.	03-06-2014
20140108058	Method and System to Determine Auto Insurance Risk - A method for providing insurance underwriting using user-centric data includes receiving data reported from an application running on a telematics unit or a mobile device, matching the received data to known locations, and generating a score based on the reported data and the matched data. The reported data and the matched data are used to determine miles traveled. A valid trip is determined. A valid driver is determined to associate with the valid trip. A sum of valid trips is determined over a period of time. Location data for the mobile device or the telematics unit is determined. The location data is determined using network-based resources. The location data is determined using the mobile device or the telematics unit. The location data can be determined using a combination of network-based resources and the mobile device or the telematics unit. A change in location is categorized into a trip signature.	04-17-2014
20150084757	METHODS AND SYSTEMS FOR DETERMINING AUTO ACCIDENTS USING MOBILE PHONES AND INITIATING EMERGENCY RESPONSE - A method for providing automatic crash management (ACM) is provided. An ACM application is enabled on a mobile device. Data is collected from a plurality of sensors associated with the mobile device. The data from the plurality of sensors is processed with the ACM application. The processed data is monitored with accident logic of the ACM application running on the mobile device to determine whether a crash has been detected. The data from the plurality of sensors is automatically streamed to the off-board server for further analysis upon detection of the crash.	03-26-2015

Keith Allen Bourne, Urbana, IL US

Patent application number	Description	Published
20110132169	HIGH-PRECISION MICRO/NANO-SCALE MACHINING SYSTEM - A high precision micro/nanoscale machining system. A multi-axis movement machine provides relative movement along multiple axes between a workpiece and a tool holder. A cutting tool is disposed on a flexible cantilever held by the tool holder, the tool holder being movable to provide at least two of the axes to set the angle and distance of the cutting tool relative to the workpiece. A feedback control system uses measurement of deflection of the cantilever during cutting to maintain a desired cantilever deflection and hence a desired load on the cutting tool.	06-09-2011

Keith Edward Bourne, Ann Arbor, MI US

Patent application number	Description	Published
20110231445	METHOD, APPARATUS, AND SYSTEM FOR INFORMATION SHARING WITHIN A SOCIAL NETWORK - A method for sharing a central knowledge base across social networks, the method comprising: allowing a user to generate a piece of information and store it on a server; allowing the user to merge pieces of information into one or more collections of information which are saved on one or more servers; allowing the user to access other pieces and collections of information which are stored on one or more servers; enabling the user to request automated updates of pieces and collections of information which are stored on one or more servers; allowing the user to restrict modifications to information which he generated and which is stored on one or more servers; and allowing the user to modify pieces and collections of information which were generated by other users and are stored on one or more servers, where permission to modify the information has been granted by the first user to generate the information.	09-22-2011

Keith Edward Bourne, Southfield, MI US

Patent application number	Description	Published
20140068664	METHOD FOR ADDING AN OBJECT MAP TO A VIDEO SEQUENCE - A method to provide image recognition within a video and to add time-based data to the video. The time-based data is from a manually or automatically classified and indexed video database. The time-based data is dependent upon the recognized image within the video. Hence, the time-based data is available as a function of times when the image is available.	03-06-2014

Leslie Bourne, Coatesville, PA US

Patent application number	Description	Published
20140273038	BIOLUMINESCENT METAL ION ASSAY - A method for determining metal ions, both qualitatively and quantitatively, is disclosed. The method utilizes emission from fluorescence resonance energy transfer from a luciferase-carbonic anhydrase conjugate or fusion protein to an acceptor ligand in the presence of metal ion bound to the protein to measure free metal ion concentrations down to picomolar concentration ranges. The method is relatively insensitive to contaminants, and so can be used to measure metal ion concentrations in cells, body fluids or environmental samples without extensive sample preparation.	09-18-2014

Mary Lou Garber Bourne, Harrisonburg, VA US

Patent application number	Description	Published
20110191136	SYSTEM AND METHOD FOR WEB-BASED SPORTS EVENT SCHEDULING - A system and methods are provided for communication between entities that need to coordinate on scheduling events. Communication between schedulers, such as coaches, athletic administrators or organization administrators who may be in charge of a multiplicity of sports or activities at institutions, such as colleges or universities, who need to connect and communicate on a particular task. These tasks may include scheduling of events such as sports competitions or other events or activities in which there may be shared or common interests or a shared network of users, players or participants. Search by criteria to find matching potential opponents for scheduling events is also provided. Automatic schedule updates are maintained, typically in a logically centralized database, facilitated by a messaging system to facilitate ease of scheduling.	08-04-2011

Patricia Bourne, Palo Alto, CA US

Patent application number	Description	Published
20150355184	ANTIBODIES THAT BIND TO HUMAN PROGRAMMED DEATH LIGAND 1 (PD-L1) - The present disclosure provides isolated antibodies that specifically bind to human PD-L1, as well as antigen binding fragments of such antibodies, and kits comprising the anti-PD-L1 antibodies or binding fragments and a set of reagents for detecting a complex of the antibody, or antigen binding fragment thereof, bound to human PD-L1. The antibodies and antigen binding fragments of this disclosure are useful for immunohistochemical detection of human PD-L1 expression in tissue samples. Nucleic acid molecules encoding the antibodies and antigen binding fragments of this disclosure, as well as expression vectors and host cells for expression thereof, are also provided.	12-10-2015

Philip E. Bourne, Poway, CA US

Patent application number	Description	Published
20110022449	Multimedia User Interfaces For Documents And Associated Digital Videos - Generating a multimedia user interface with synchronized digital video and document content can include receiving a document, receiving a digital video that corresponds to the document, generating a plurality of mappings, wherein each of the mappings maps a section of the document to a segment of the digital video, and generating a multimedia user interface responsive to the document, the digital video, and the plurality of mappings.	01-27-2011

Richard C. Bourne, Davis, CA US

Patent application number	Description	Published
20090126913	Vertical counterflow evaporative cooler - An evaporative plate-type heat exchanger is provided having a plurality of alternating first plates and second plates positioned in side-by side relationship to form a top surface, a bottom surface, a front surface and a rear surface. The first and second plates form a plurality of dry air flow passages, between first faces of the first plates and first faces of adjacent second plates, that are in communication with dry air flow inlet openings and dry air flow outlet openings formed in the front surface. The first and second plates form a plurality of dry air flow passages, between second faces of the first plates and second faces of adjacent second plates, that are in communication with wet air flow inlet openings formed in the bottom surface and with wet air flow outlet openings formed in the rear surface. A method of forming the plate-type heat exchanger includes forming alternating first plates and second plates in a continuous sheet, and folding the continuous sheet in a fan fold arrangement.	05-21-2009
20100212346	WICKING CONDENSATE EVAPORATOR FOR AN AIR CONDITIONING SYSTEM - One embodiment of the present invention provides an air conditioning (AC) system that evaporates its own condensate. This AC system includes a condenser coil and an evaporator coil that produces condensate. The AC system also includes a wicking-evaporative device that is configured to wick and evaporate the condensate in the vicinity of the condenser coil.	08-26-2010

Richard Curtis Bourne, Davis, CA US

Patent application number	Description	Published
20120055921	Space- and Structurally-Efficient Recta-Cylinder Molded Liquid Storage Tanks - This invention is an improvement to the shape of liquid storage tanks, in particular to unpressurized molded polymer tanks used for thermal storage in solar systems. Although solar storage tanks represent the first commercial application, this invention is well suited to ambient-temperature water and chemical storage tanks as well.	03-08-2012
20120104003	Horizontal Extraction and Return Extensions in liquid storage tanks - This invention is an improvement to the shape of liquid storage tanks, in particular to unpressurized molded polymer tanks used for thermal storage in solar systems. All aspects of this invention are well suited to solar storage tanks, and individual aspects are suited to other liquid tank applications.	05-03-2012
20150033783	Integrated System for Cooling a Building, Collecting Rainwater, and Cleaning a Rooftop Solar Array - This invention provides a simple integrated system that uses roof-spray, water collection, and water storage components to cool a building, collect and store rainwater, and clean a rooftop solar array.	02-05-2015
20160102922	Packaged Helical Heat Exchanger - This invention provides an economical helical polymeric heat exchanger that packages tightly for handling and then is quickly assembled to its full length prior to placement in either the ground or water.	04-14-2016

Robert Bourne, Orlando, FL US

Patent application number	Description	Published
20140310181	ANONYMOUS ONLINE PAYMENT SYSTEMS AND METHODS - In various embodiments, a server grants access to a plurality of anonymous one-time-usable, time-sensitive encrypted tokens that identify consumer purchase orders. A plurality of certified merchant servers are certified by being provided with an application to securely connect the certified merchant servers to the server for, among other things, transmitting purchase order data to the server for use in generating the tokens. A plurality of financial institution servers can also be certified by being configured for use with an application that enables secure connection to the server for, among other things, requesting the tokens.	10-16-2014

Robert H. Bourne, New York, NY US

Patent application number	Description	Published
20090313203	PREDICTIVE WIKI OPTIMIZATION SOFTWARE APPLICATION - A method, system, and device readable medium for running a predictive wiki optimization application is disclosed. The optimization application provides an improved decision-making or valuation method for formalizing and systematizing the decision-making or valuation process. The application leverages collective knowledge about a field of endeavor in order to yield better decisions or more accurate valuations. In some embodiments, the application represents an application of predictive markets within a wiki-style wrapper.	12-17-2009

Sidney Bourne, Sudbury, MA US

Patent application number	Description	Published
20100000943	METHOD AND APPARATUS FOR DESOLVATING FLOWING LIQUID - Methods and apparatus for desolvating flowing liquid streams while retaining temporal resolution of dissolved substrates are disclosed. A novel small-scale self-regulating spray dryer preserves temporal resolution while desolvating a liquid chromatography eluent stream and depositing the solute onto an optical surface for infrared spectrographic analysis. The liquid eluent is pumped through a heated nebulizer to create a high-speed jet of solute containing liquid and solvent vapor. This jet is directed circumferentially inside a hot cylindrical cavity. Centrifugal force causes the larger liquid droplets to travel along the outer diameter of the cavity. The cavity surface is heated to cause the droplets to film boil. Film boiling reduces droplet contact with the cavity surface thereby retaining the solute in the droplets. The solute temperature is limited by controlling the pressure into which the solvent evaporates from the droplets. When the droplets are sufficiently small, Stokes drag from the exiting solvent vapor carries the droplets out through the center of the cylindrical cavity. After exiting, the superheated solvent vapor further dries the droplets. Solvent vapor is removed by condensation onto a cooled surface. A freezing point reducing agent may be added to improve removal of solvent condensate. Stokes drag from a non-condensable gas maintains the dried droplets in suspension. This suspension travels through an orifice that focuses the impaction of the dried droplets onto the optical surface for infrared analysis. The deposition surface is in an evacuated chamber and is temperature controlled to freeze liquid solutes yet allowing sublimation of residual solvent.	01-07-2010

Stephen James Bourne US

Patent application number	Description	Published
20110139462	METHODS OF INVESTIGATING AN UNDERGROUND FORMATION AND PRODUCING HYDROCARBONS, AND COMPUTER PROGRAM PRODUCT - A method of investigating an underground formation underneath the earth's surface, comprising obtaining a first data set representing change in a predetermined seismic parameter over a period of time for a plurality of points in the underground formation, which first data set is derived from a time-lapse seismic survey of the earth formation spanning the period of time; obtaining a second data set representing geodetic deformation over substantially the same period of time at a plurality of locations on the earth's surface, which second data set is derived from a geodetic survey spanning the period of time; jointly processing the first and second data sets to obtain a map of a parameter related to volume change in the underground formation; wherein a geomechanical model of the underground formation is postulated; also a method of producing hydrocarbons and a computer program.	06-16-2011

Steve Bourne, Seattle, WA US

Patent application number	Description	Published
20080215896	Issuing a Publisher Use License Off-Line in a Digital Rights Management (DRM) System - A publishing user publishes digital content and issues to itself a corresponding digital publisher license to allow itself to render the published digital content. The publishing user is supplied with a publishing certificate from a digital rights management (DRM) server, where the publishing certificate allows the publishing user to so publish the digital content and to so issue the publisher license.	09-04-2008
20100281253	ISSUING A PUBLISHER USE LICENSE OFF-LINE IN A DIGITAL RIGHTS MANAGEMENT (DRM) SYSTEM - A publishing user publishes digital content and issues to itself a corresponding digital publisher license to allow itself to render the published digital content. The publishing user is supplied with a publishing certificate from a digital rights management (DRM) server, where the publishing certificate allows the publishing user to so publish the digital content and to so issue the publisher license.	11-04-2010

Steven Bourne, Seattle, WA US

Patent application number	Description	Published
20110173605	Automated Configuration and Installation of Virtualized Solutions - An installation system for a multiple device, multiple application solution may include options for installing and configuring one or more of the devices as virtual machines. The installation system may start from bare hardware, install a virtual machine host, and configure one or more devices as virtual machines. The installation system may provide a set of predefined configurations from which an administrator may choose, and some embodiments may provide various algorithms or optimization routines to select an appropriate configuration based on intended uses or other factors. The configurations may be customized to create one or more documents that may be consumed during the installation process to automate many configuration settings.	07-14-2011
20150363183	Automated Configuration and Installation of Virtualized Solutions - An installation system for a multiple device, multiple application solution may include options for installing and configuring one or more of the devices as virtual machines. The installation system may start from bare hardware, install a virtual machine host, and configure one or more devices as virtual machines. The installation system may provide a set of predefined configurations from which an administrator may choose, and some embodiments may provide various algorithms or optimization routines to select an appropriate configuration based on intended uses or other factors. The configurations may be customized to create one or more documents that may be consumed during the installation process to automate many configuration settings.	12-17-2015

Thomas M. Bourne, Mountain View, CA US

Patent application number	Description	Published
20110077672	Devices For Installing Stasis Reducing Means In Body Tissue - Devices for insertion into an atrial appendage of stasis reducing components such as mesh members, chemical bonding agents or expandable anchors are disclosed.	03-31-2011
20140088636	DEVICES FOR INSTALLING STASIS REDUCING MEANS IN BODY TISSUE - Devices for insertion into an atrial appendage of stasis reducing components such as mesh members, chemical bonding agents or expandable anchors are disclosed.	03-27-2014

Timothy F. Bourne, Visalia, CA US

Patent application number	Description	Published
20130347156	Grapevine named '21-66-226' - A new and distinct variety of grapevine plant named ‘21-66-226’ particularly characterized by its unusual shaped berries, very firm texture, and very large, sweet berries. Additionally, berries of the new cultivar are very responsive to applications of exogenous gibberellic acid, more than doubling in size in comparison to untreated fruit.	12-26-2013
20130347157	Grapevine named '21-66-158' - A new and distinct variety of grapevine plant named ‘21-66-158’ particularly characterized by its unusual shape, very firm texture, dark green skinned berries and very large, sweet berries. Additionally, berries of the new cultivar are very responsive to applications of exogenous gibberellic acid, almost doubling in size in comparison to untreated fruit.	12-26-2013

William Scott Bourne, Boynton Beach, FL US

Patent application number	Description	Published
20130063932	Surface Mount Light With Interchangeable Diffusers - A surface mount light (	03-14-2013