Patent application number | Description | Published |
20140271905 | Neural Progenitor Cell Differentiation - Differentiation and stability of neural stem cells can be enhanced by in vitro or in vivo culturing with one or more extracellular matrix (ECM) compositions, such as collagen I, IV, laminin and/or a heparan sulfate proteoglycan. In one aspect of the invention, adult mammalian enteric neuronal progenitor cells can be induced to differentiate on various substrates derived from components or combinations of neural ECM compositions. Collagen I and IV supported neuronal differentiation and extensive glial differentiation individually and in combination. Addition of laminin or heparan sulfate to collagen substrates unexpectedly improved neuronal differentiation, increasing neuron number, branching of neuronal processes, and initiation of neuronal network formation. In another aspect, neuronal subtype differentiation was affected by varying ECM compositions in hydrogels overlaid on intestinal smooth muscle sheets. The matrix compositions of the present invention can be used to tissue engineer transplantable innervated GI smooth muscle constructs to remedy aganglionic disorders. | 09-18-2014 |
20140377232 | INNERVATION OF ENGINEERED STRUCTURES - Methods of generating an innervated muscle structures are disclosed as well as bioengineered structures for tissue repair or regeneration. The methods can include the steps of obtaining populations of smooth muscle cells and neuronal progenitor cells and then seeding the cells together onto a matrix material, followed by culturing the seeded cells to form an innervated smooth muscle cell construct of directionally oriented smooth muscle cells. In one embodiment, the neuronal progenitor cells can be seeded first as neurospheres in a biocompatible solution, e.g., a collagen/laminin solution, and allowed to gel. Next, a second suspension of smooth muscle cells can be deposited as separate layer. Multiple layer structures of alternating muscle or neuron composition can also be formed in this manner. Differentiation of the neuronal progenitor cells can be induced by exposure to a differentiation medium, such as Neurobasal A medium and/or exposure to a differentiating agent, such as B-27 supplement. The innervated muscle structures can be disposed around a tubular scaffold, e.g., a chitosan-containing tube and further cultured to form tubular, bioengineered structures and two or more innervated muscle structures can be joined together to form an elongate composite structure. | 12-25-2014 |
20140379083 | TUBULAR BIOENGINEERED SMOOTH MUSCLE STRUCTURES - Methods of generating tubular, bioengineered, smooth muscle structures are disclosed as well as bioengineered tissue for tubular organ repair or replacement. The methods can include the steps of obtaining smooth muscle cells; culturing the muscle cells to form a smooth muscle cell construct of directionally oriented smooth muscle cells; disposing the smooth muscle cell construct around a tubular scaffold; and culturing construct and scaffold in a growth media until a smooth muscle cell structure is achieved. The step of obtain smooth muscle cells can further include obtaining autologous smooth muscle cells from a subject. In one preferred embodiment, the muscle cells can first be on a fibrin substrate to form a muscle construct, which is then disposed around a tubular scaffold, for example, a chitosan scaffold. The methods of the present invention can further include connecting two or more tubular structures together to form an elongate composite structure. | 12-25-2014 |
Patent application number | Description | Published |
20090003206 | BANDWIDTH-BASED ADMISSION CONTROL MECHANISM - A device generates a service protection factor (SPF | 01-01-2009 |
20090103555 | LABEL AND EXP FIELD BASED MPLS NETWORK DEVICE - A network device receives a label-switched-path (LSP) labeled data packet, maps the LSP labeled data packet to an input queue, maps a data packet in the input queue to an output queue based on a received LSP label value and a received exp label value, and transmits the LSP labeled data packet from the output queue. | 04-23-2009 |
20090141622 | PINNING AND PROTECTION ON LINK AGGREGATION GROUPS - A device may assign a virtual local area network (VLAN) to one or more specific links in a link aggregation group (LAG), and send traffic from the VLAN on the assigned one or more specific LAG links. Traffic from the same VLAN may be sent on one link in the LAG by selecting a hashing criterion or by pinning the VLAN to a primary link in the LAG and another link for redundancy purposes. | 06-04-2009 |
20090141731 | BANDWIDTH ADMISSION CONTROL ON LINK AGGREGATION GROUPS - A device may receive a bandwidth (B) available on each link of a link aggregation group (LAG) that includes a number (N) of links, assign a primary LAG link and a redundant LAG link to a virtual local area network (VLAN), set an available bandwidth for primary link booking to (B−B/N), and set an available bandwidth for redundant link booking to (B/N). | 06-04-2009 |
20100195530 | BANDWIDTH-BASED ADMISSION CONTROL MECHANISM - A device generates a service protection factor (SPF | 08-05-2010 |
20110090916 | LABEL AND EXP FIELD BASED MPLS NETWORK DEVICE - A network device receives a label-switched-path (LSP) labeled data packet, maps the LSP labeled data packet to an input queue, maps a data packet in the input queue to an output queue based on a received LSP label value and a received exp label value, and transmits the LSP labeled data packet from the output queue. | 04-21-2011 |
20110093893 | DATA DISTRIBUTION - A device may include a communication interface configured to receive programming information from a service provider multicast over multiple channels. The device may also include logic configured to decode the programming information received over the multiple channels, assemble a programming guide based on the decoded programming information and output the programming guide to an output device for display. | 04-21-2011 |
20110162013 | HOME NETWORK MANAGEMENT - A method includes storing, at a first network device configured to communicate with at least one set top box (STB) and at least one digital video recorder (DVR), information identifying parameters associated with bandwidth in a home network. The method may also include receiving, at a first network device in the home network, a request having a corresponding first bandwidth and identifying a class of traffic associated with the request. The method may further include determining whether the first bandwidth is less than an available bandwidth associated with the identified class of traffic, approving the request when the first bandwidth is less than the available bandwidth, and modifying the available bandwidth associated with the identified class of traffic in response to approving the request. | 06-30-2011 |
20110267941 | PINNING AND PROTECTION ON LINK AGGREGATION GROUPS - A device may assign a virtual local area network (VLAN) to one or more specific links in a link aggregation group (LAG), and send traffic from the VLAN on the assigned one or more specific LAG links. Traffic from the same VLAN may be sent on one link in the LAG by selecting a hashing criterion or by pinning the VLAN to a primary link in the LAG and another link for redundancy purposes. | 11-03-2011 |
20130142166 | COLLAPSED MOBILE ARCHITECTURE - A collapsed or compact mobile architecture system includes connection nodes each comprising an access interface and at least one network interface; a backhaul network coupled to each of the connection nodes; and a mobility control unit coupled to the backhaul network. The mobility control unit comprises an Internet Protocol (IP) address server. Each of the connection nodes is configured to receive attachment requests from at least one user device. The mobility control unit is configured to receive first control plane signals from the connection nodes based on the attachment requests and transmit second control plane signals to the connection nodes based on the attachment requests. The mobility control unit is further configured to assign an IP address to each of the at least one user devices, based on the receive first control plane signals. | 06-06-2013 |
20140092772 | IP AGGREGATION FOR LTE-BASED MOBILE NETWORKS - A mobile architecture system includes a plurality of connection nodes each comprising an access interface and at least one network interface. A plurality of aggregation layer devices are each coupled to respective sets of connection nodes to form aggregation regions. A backhaul network is coupled to each of the aggregation layer devices, and a mobility entity is coupled to the backhaul network, wherein each of the connection nodes is configured to receive attachment requests from at least one user device. The aggregation layer devices are configured to assign IP addresses to user devices connected to connection nodes coupled to the respective aggregation layer devices. The aggregation layer devices are configured to determine IP routes from the backhaul network to the connection nodes based on the assigned IP addresses. The aggregation layer devices are further configured to notify respective connection nodes regarding the IP addresses assigned to connected user devices. | 04-03-2014 |
20150280980 | METHOD AND APPARATUS FOR DYNAMIC PROVISIONING OF COMMUNICATION SERVICES - An approach is provided for determining a cloud provider identifier associated with a request to provision one or more communication services. The approach further involves validating the request by matching the cloud provider identifier against another copy of the cloud provider identifier associated with a session over which the provisioning request was received. | 10-01-2015 |
20150281046 | METHOD AND APPARATUS FOR CLOUD PROVISIONING OF COMMUNICATION SERVICES - An approach for cloud provisioning of consumer services based on requested services. The approach uses customer request for services and current network utilization patterns to most efficiently and effectively provision network resources. For example, a network manager establishes one or more terms for a cloud provider based on one or more provider network provisions. The network manager further determines a customer profile subscription based on customer credentials, cloud provider credentials, and a combination thereof. Then, the network manager delivers one or more credentials based on the cloud provider, and generates a routing path to the cloud provider based on the subscription and/or service request. | 10-01-2015 |
20150281063 | METHOD AND SYSTEM FOR NETWORK TRAFFIC STEERING BASED ON DYNAMIC ROUTING - An approach is provided for steering network traffic (e.g., IP traffic) based on dynamic routing to a service node or a chain of service nodes that can provide in-line services. In an exemplary embodiment, traffic is steered from a first router to an in-line service router by tunneling through a second router, wherein in-line service router is configured to provide in-line services to the traffic. | 10-01-2015 |
20160100364 | REDUCING POWER CONSUMPTION ON LOCATION REFERENCE DEVICES - A device may request location information for a location reference device (LRD); receive, based on the request, the location information for the LRD via a cellular network connection; transmit, via the cellular network, an instruction to direct the LRD to activate a non-cellular radio on the LRD; receive wireless signals outputted via the non-cellular radio; determine a distance between the user device and the LRD based on a strength of the wireless signals received by the user device; and audibly or visually indicate, by the user device, the determined distance between the user device and the LRD. | 04-07-2016 |
Patent application number | Description | Published |
20090059460 | TUNABLE AND AIMABLE ARTIFICIAL LIGHTENING PRODUCING DEVICE - A tunable and aimable artificial lightning producing device for tetanizing human voluntary muscle, disabling vehicular electronic ignition systems, and for pre-detonating wired explosives. A spark gap shaping apparatus controls a spark generated by a Tesla coil. A first stage directionalizer warps a normally spherical plasma field from the Tesla coil into an oval plasma field for confining the spark to within that shape. A second stage directionalizer converges multiple beams to successive points just ahead of a plasma field created by the first stage directionalizer without ionizing the beams, thereby maintaining ionization of a path of the spark. The spark is progressively arced to these points, thereby maintaining the path of the spark. | 03-05-2009 |
20120019006 | COAXIAL WIND TURBINE - Disclosed is a gearbox with two driver gears that are phase shifted 180 degrees with respect to a driven gear so that counter-rotation of the driver gears combine to rotate the driven gear together. The gearbox can be used to couple a counter-rotating, coaxial wind turbine rotors by coupling the driver gears to the counter-rotating rotors and the driven gear to a generator so that the counter-rotating rotors on the wind turbine rotate the driven gear in the same direction. The driven gear can be coupled to a generator to produce electricity. | 01-26-2012 |
20130016215 | DAZZLING LASER RIFLE - Disclosed is a handheld long range dazzling laser including a 1 Watt or greater laser light source, a focus-adjustable beam expander, a power source, a trigger and a magnifying targeting device. Also disclosed is a method of discounting ship insurance rates based on equipping ships with the disclosed handheld long range dazzling laser. | 01-17-2013 |
20140109754 | ELECTRICAL DISCHARGE SYSTEM AND METHOD FOR NEUTRALIZING EXPLOSIVE DEVICES AND ELECTRONICS - Disclosed are a system and method for discharging electrical potential into the earth to disable or destroy electronics and/or explosive devices. The disclosed system includes an electrical power supply providing a pulsed electrical potential exceeding 30,000 volts with at least 30 Joules of energy in each pulse. The system includes a cathode emitter and an anode emitter configured to be moved along the earth in close proximity to the earth. The electrical potential is discharged into the earth through the cathode emitter and/or the anode emitter. | 04-24-2014 |
20140124612 | MULTI-MODE VEHICLE - A multi-mode vehicle is disclosed that can be used in two or more of land, water and ground effect flight. The vehicle includes a first engine driving the vehicle's wheels and a second engine driving a fan. The vehicle includes removable wings, a removable horizontal stabilizer and a rudder. The second engine and fan, operating alone, provide insufficient thrust for the wings to lift the vehicle off the ground. The first and second engines, operating together, provide sufficient thrust for the wings to lift the vehicle into ground effect flight. The second engine and fan provide sufficient thrust for the vehicle to maintain ground effect flight. | 05-08-2014 |
20140305290 | METHOD FOR NEUTRALIZING EXPLOSIVES AND ELECTRONICS - Disclosed is a system for detonating a buried explosive device by discharging an electric discharge with at least five joules of energy to detonate the buried explosive device. | 10-16-2014 |
Patent application number | Description | Published |
20110182828 | C20-C21 SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS - The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having the general structure: | 07-28-2011 |
20110262368 | C21 THIOETHERS AS GLUCOCORTICOID RECEPTOR AGONISTS - The present invention provides compounds of Formula (VII) and 11-keto analogs thereof, and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, and isomers of said compounds and said 11-keto analogs, having the general structure formula (VII): wherein L, R | 10-27-2011 |