Biemans
Augustines Gerardus Maria Biemans, Geldrop NL
Patent application number | Description | Published |
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20090194911 | OPTICAL MICRO-ARRAY FOR E.G. MICRO SENSORS - Method for manufacturing a polymer body ( | 08-06-2009 |
20100025870 | METHOD AND APPARATUS FOR MANUFACTURING A POLYMERIC ARTICLE - The invention is directed to a method for manufacturing, in one production step and from one material, a polymeric article having at least one optical transparent area and at least one optical non-transparent area. The inventors found that it is possible to simultaneously create transparent and non-transparent areas, while the article is formed, by influencing specific cooling parameters. | 02-04-2010 |
Barbara Biemans, Riehen CH
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20130123254 | PHARMACEUTICALLY ACCEPTABLE MGLUR5 POSITIVE ALLOSTERIC MODULATORS AND THEIR METHODS OF IDENTIFICATION - The present invention relates to mGluR5 positive allosteric modulators (PAM) and methods for identifying pharmaceutically acceptable compounds with high tolerability and safety, which method comprises the use of at least one non-competitive mGluR5 allosteric modulator which has a shift factor measured at 10 uM glutamate concentration below 3.0, | 05-16-2013 |
Michael Dennis Biemans, Eindhoven NL
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20100218206 | VIEWER PRESENCE DETECTION - One embodiment of the present invention sets forth a method for determining a chance that a user is present at a current time while a client device is tuned to a channel by monitoring a user input to the client device and determining a time when the user provides the user input. At the time when the user provides the user input, the chance is assigned an initial value. After that, the chance varies over time according to a first function. The chance that the user is present at the current time is then determined using the initial value and the first function. As a result, a chance of a user being present while a client device plays out media segments may be determined without incurring the costs of providing additional hardware and without requiring the user to register and unregister. | 08-26-2010 |
Michael-Dennis Biemans, New York, NY US
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20150189374 | SYSTEM AND METHOD FOR OPTIMIZED CHANNEL SWITCHING IN DIGITAL TELEVISION BROADCASTING - A system and method for masking/reducing the switch time from an analog or digital television channel to another digital television channel and back. Various optimizations which may be used individually or in combination to minimize the potential disruption to the viewer. This optimization is especially important when the channel switch is made automatically by the receiver, such as the case where the presentation of one television program is temporarily continued on another channel. | 07-02-2015 |
Ralph Biemans, Rixensart BE
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20100291137 | METHOD FOR REFOLDING NEISSERIAL NSPA PROTEIN - The present invention provides an isolated refolded NspA protein, and a method of preparing it. | 11-18-2010 |
20110033500 | VACCINE COMPOSITIONS COMPRISING L2 AND/OR L3 IMMUNOTYPE LIPOOLIGOSACCHARIDES FROM LGTB-NEISSERIA MENINGITIDIS - The present invention relates to the field of neisserial vaccine compositions, their manufacture, and the use of such compositions in medicine. More particularly it relates to processes of making novel engineered meningococcal strains which are more suitable for the production of neisserial, in particular meningococcal, outer-membrane vesicle (or bleb) vaccines. Advantageous processes and vaccine products are also described based on the use of novel LOS subunit or meningococcal outer-membrane vesicle (or bleb) vaccines which have been rendered safer and/or more effective for use in human subjects. In particular combinations of gene downregulations are described such as PorA and OpA, PorA and OpC, OpA and OpC, and PorA and OpA and OpC. Alternatively, or in addition, lgtB | 02-10-2011 |
20110311577 | METHOD OF PRODUCING A VACCINE - The present invention relates to a method for purifying bacterial cytolysins such as pneumococcal pneumolysin. A single chromatography step produces excellent purification of the cytolysin by binding soluble aggregated cytolysin to a hydrophobic interaction chromatography material in the presence of detergent and high salt. | 12-22-2011 |
20120027800 | NEISSERIAL VACCINE COMPOSITIONS COMPRISING A COMBINATION OF ANTIGENS - The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membrane-associated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the neisserial life cycle, resulting in a more effective immune response. | 02-02-2012 |
20120064119 | NEISSERIAL VACCINE COMPOSITIONS COMPRISING A COMBINATION OF ANTIGENS - The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membrane-associated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the neisserial life cycle, resulting in a more effective immune response. | 03-15-2012 |
20120064120 | NEISSERIAL VACCINE COMPOSITIONS COMPRISING A COMBINATION OF ANTIGENS - The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membrane-associated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the neisserial life cycle, resulting in a more effective immune response. | 03-15-2012 |
20140010843 | METHOD OF DETOXIFICATION - The present invention relates to a method of detoxifying bacterial cytolysins such as pneumococcal pneumolysin, utilizing chemical cross-linking compounds. | 01-09-2014 |
Rogier Biemans, Boxmeer NL
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20100260795 | Carrier Particle for a Microorganism or Subunit Thereof, Pharmaceutical Composition Comprising such Particles, Method for Preparation of this Composition and Its Use in the Treatment of Animals - The invention pertains to a carrier particle comprising a hydrophilic phase containing a micro-organism and/or subunit thereof, the hydrophilic phase being dispersed in a hydrophobic continuous phase being solid at room temperature, wherein the hydrophobic phase is constituted to undergo a solid-to-liquid conversion at a temperature above room temperature, the conversion comprising a first order transition. The invention also pertains to a pharmaceutical composition comprising said particles, a method for preparation the pharmaceutical composition and the use of this composition in the treatment of an animal. | 10-14-2010 |
Rogier Biemans, Nijmegen NL
Patent application number | Description | Published |
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20130337150 | Method of Protecting Biologically Active Substances against Denaturation - A method of protecting a biologically active substance against denaturation, wherein a liquid ( | 12-19-2013 |