Bianchi, Milano
Daniele Bianchi, Milano IT
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20110160479 | PROCESS FOR THE PRODUCTION OF ESTERS OF LEVULINIC ACID FROM BIOMASSES - A new process is described for the direct synthesis of esters of levulinic acid starting from biomasses containing one or more polysaccharides and from aliphatic alcohols, in the presence of a suitable organic acid catalyst. In particular, the biomasses can be lignin-cellulose biomasses. The esters thus obtained can be used as oxygenated components in the formulation of fuels for motor vehicles, with the aim of reducing the particulate emissions. | 06-30-2011 |
Davide Bianchi, Milano IT
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20120289477 | BIOTECHNOLOGICAL SULPHATED CHONDROITIN SULPHATE AT POSITION 4 OR 6 ON THE SAME POLYSACCHARIDE CHAIN, AND PROCESS FOR THE PREPARATION THEREOF - A process for the preparation of a chondroitin sulphate salt with an average molecular weight (Mw) of 10-30 kDa via chemical sulphation of an unsulphated chondroitin backbone is provided. The unsulphated chondroitin can be obtained by acid hydrolysis of a capsular polysaccharide K4 made directly from | 11-15-2012 |
20140315854 | BIOTECHNOLOGICAL SULPHATED CHONDROITIN SULPHATE AT POSITION 4 OR 6 ON THE SAME POLYSACCHARIDE CHAIN, AND PROCESS FOR THE PREPARATION THEREOF - The present invention discloses a process for the production of chondroitin sulphate with an average molecular weight (Mw) of 10-30 kDa by chemical sulphation starting from an unsulphated chondroitin backbone, obtained in turn by acid hydrolysis of capsular polysaccharide K4 made directly from | 10-23-2014 |
Fabrizio Bianchi, Milano IT
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20150057159 | METHOD TO IDENTIFY ASYMPTOMATIC HIGH-RISK INDIVIDUALS WITH EARLY STAGE LUNG CANCER BY MEANS OF DETECTING miRNAs IN BIOLOGIC FLUIDS - A diagnostic and/or prognostic model of at least 5 serum miRNAs selected among a group of 34 miRNAs that identifies subjects with early stage lung cancer, namely non-small cell lung carcinomas (NSCLCs), in a population of asymptomatic high-risk individuals, with 80% accuracy. The model could also distinguish between benign and malignant lesions and is sensitive enough to capture the disease onset. In addition, the model could also diagnose or confirm a diagnosis of lung cancer in symptomatic patients, and monitor the lung tumor status after treatment with surgery and/or chemotherapy and/or radiotherapy in a subject with such lung cancer. | 02-26-2015 |
Giuseppe Bianchi, Milano IT
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20090275542 | AZAHETEROCYCLYL DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS - Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na+, K+-ATPase. They are useful for the preparation of a medicament for the treatment of a disease caused by the hypertensive effects of endogenous ouabain, such as renal failure progression in autosomal dominant polycystic renal disease (ADPKD), preeclamptic hypertension and proteinuria and renal failure progression in patients with adducin polymorphisms. | 11-05-2009 |
20100303896 | 5BETA, 14BETA-ANDROSTANE DERIVATIVES USEFUL FOR THE TREATMENT OF RESTENOSIS AFTER ANGIOPLASTIC OR ENDOARTHERECTOMY AND DISEASES DUE TO ORGAN FIBROSIS - Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of obstructive vascular lesions following vascular surgery and for the prevention and/or treatment of diseases due to organ fibrosis. | 12-02-2010 |
20110053902 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS - Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart failure and hypertension. The compounds are inhibitors of the enzymatic activity of the Na | 03-03-2011 |
20120028945 | 5-Beta, 14-Beta-Androstane Derivatives Useful For The Treatment Of Proteinuria, Glomerulosclerosis And Renal Failure - Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of proteinuria, glomerulosclerosis or renal failure. | 02-02-2012 |
20130018024 | METHODS AND SYSTEMS FOR PHARMACOGENOMIC TREATMENT OF CARDIOVASCULAR CONDITIONS - Methods and systems are provided herein that are based on the effects of genetic variations on the biological activities associated to rostafuroxin in an individual. In particular, compositions, methods and systems are herein described that are based on an indentified influence on an individual response to rostafuroxin of one or more polymorphisms in an intergenic or intragenic region of a gene selected from the group consisting of KCNS3, THSD7A, FAM46A, LOC389970, HLA-G, and TTC29, and/or a genetic variation in linkage disequilibrium therewith. | 01-17-2013 |
Marco Bianchi, Milano IT
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20090062187 | Use of Hmgb1 for Wound Healing - The present invention describes the role of HMGB1 in improving wound healing, in particular in a model of diabetes. Other evidences based on the effect of glycyrrhizin, the underexpression of HMGB1 in the skin and fibroblast of diabetic subjects, the accumulation of RAGE in the skin of diabetic mice and the chemoattractant properties of HMGB1 on normal and diabetic human cells demonstrate that HMGB1 can be advantageously utilized for preparing medicament specifically devoted to wound healing, in particular for diabetic subjects. | 03-05-2009 |
Marco Emilio Bianchi, Milano IT
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20090069227 | Use of HMGB1 to promote stem cell migration and/or proliferation - It is described a method to promote stem cell migration and/or proliferation in cell culture or in vivo comprising the step of exposing such cells to an effective amount of the HMGB1 protein or its active fragment. | 03-12-2009 |
Marco E. Bianchi, Milano IT
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20140127134 | TREATMENT AND PREVENTION OF CANCER WITH HMGB1 ANTAGONISTS - Embodiments provided herein relate to methods and compositions for treating or preventing cancer. More particularly, several embodiments are drawn to treating or preventing malignant mesothelioma with antagonists of HMGB1. | 05-08-2014 |
Massimiliano Bianchi, Milano IT
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20100040469 | VARIABLE-PITCH PROPELLER - Variable-pitch propeller ( | 02-18-2010 |
20100260606 | NAUTICAL VARIABLE-PITCH PROPELLER - Nautical variable-pitch propeller of the type comprising a hub driven by a drive shaft, an outer case externally constrained to the hub, and one or more blades, wherein each blade is constrained to the outer case freely to rotate around the (Y-Y) axis of an own shaft, the afore said outer case making each blade to rotate around the axis (X-X) of the hub, as well as a device for regulating the angular position of the blade around the (Y-Y) axis of its own shaft relatively to the hub. Advantageously, the regulating device comprises at least one moving member and means for transmitting movement from the moving member to the shaft of the blade, according to at least two different laws of motion transmission. | 10-14-2010 |
Michela Bianchi, Milano IT
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20090165375 | Waste disposal plant and related process - Waste disposal plant comprising a tank ( | 07-02-2009 |