Bertrand
Arnaud Bertrand, Nivelles BE
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20130142237 | METHODS AND DEVICES FOR DETECTING ELECTROMAGNETIC INTERFERENCE ON DATA TRANSMISSION LINES - A method for remotely detecting electromagnetic interference on a data transmission line of a communication network includes measuring at a client site a noise power spectrum on the data transmission line as a function of frequency, for a frequency range. The noise is present when the data transmission line is not carrying a data signal. The method further includes forwarding the measured noise power spectrum to a remote computer at a network operator's site, determining periodicities in the measured power spectrum by the remote computer, and determining the switching frequency of a power supply unit at the client site by the remote computer based on periodicities in the power spectrum. | 06-06-2013 |
Christine Bertrand, Chaumont-Gistoux BE
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20100307597 | Pipes for Transporting Water Containing Chloramine - This invention is related to the preparation of polyethylene pipe resins suitable for transporting hot and cold water containing chloramine. | 12-09-2010 |
20100323142 | Pipes for Transporting Water Containing Chlorine - This invention is related to the preparation of polyethylene pipe resins suitable for transporting water containing chlorine. | 12-23-2010 |
20110033648 | Coloured Pipes for Transporting Disinfectant-Containing Water - This invention relates to the use of a coloured polyethylene pipe for transporting water containing disinfectant. The pipe is prepared from a polyethylene resin, that is produced with one or more single site catalyst systems, and that comprises blue pigments and anti-UV additive. | 02-10-2011 |
20110281053 | Pipes For Transporting Water Containing Chlorine - This invention is related to the preparation of polyethylene pipe resins suitable for transporting water containing chlorine. | 11-17-2011 |
20120000534 | Pipes for Transporting Water Containing Chlorine Dioxide - This invention is related to the preparation of polyethylene pipe resins suitable for transporting hot and cold water containing chlorine dioxide. | 01-05-2012 |
20130236671 | Resin and Pipes for Transporting Water Containing Chlorine Dioxide - This invention is related to the preparation of polyethylene pipe resins suitable for transporting hot and cold water containing chlorine dioxide. | 09-12-2013 |
Christophe Bertrand, Vacheresse Les Bones FR
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20150343962 | MULTIMEDIA SCREEN SUPPORT NOTABLY FOR A MOTOR VEHICLE INSTRUMENT PANEL - A multimedia screen support, notably for an instrument panel of a motor vehicle, including a casing in which a carriage slides between a retracted position inside the casing and a deployed position outside the casing, wherein the carriage supports a stand pivoted at its base between a position in which it is laid down against the carriage, allowing the carriage and the stand to be retracted into the casing, and a raised position for holding a multimedia screen bearing on a bottom ledge of the stand, the bottom ledge also being movable relative to the base of the stand pivoted on the carriage, between an upper position which frees space below the stand and a lower position for lowering the position of a multimedia screen, notably in order to limit the extent to which it protrudes above the top edge of the stand. | 12-03-2015 |
Christophe Bertrand, Vacheresse Les Basses FR
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20150367706 | AIR DISTRIBUTION DUCT FOR MOTOR VEHICLE - An air distribution duct configured to be connected to a heating and/or air-conditioning device of a motor vehicle, the air distribution duct including: a connection end configured to be connected to the heating and/or air conditioning device; a closed other end; a longilinear main branch with one end which forms the closed end and the other end which forms the connection end, one face of the main branch being pierced with one or a number of orifices; at least one other orifice situated on a secondary branch one end of which is connected to the main branch and the free other end of which is closed, the at least one other orifice being on a face situated on a same side of the duct as the other orifices of the main branch. | 12-24-2015 |
Damien Bertrand, Dhuy BE
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20160059042 | METHOD AND DEVICE FOR COMPUTING IN A VOLUME PHYSICAL AND/OR RADIOBIOLOGICAL QUANTITIES INDUCED BY AN ION BEAM - The method of the invention comprises the steps of: providing a reference ion beamlet; determining in a phantom ( | 03-03-2016 |
Daniel C. Bertrand, Geneva CH
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20090123945 | CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF - The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of α7 nicotinic acetylcholine receptors. | 05-14-2009 |
20120219967 | CHOLINERGIC/SEROTONINERGIC RECEPTOR AND USES THEREOF - The present invention describes new cholinergic/serotoninergic chimeric receptors and provides methods and compositions suitable for screening for ligands such as agonists, antagonists and allosteric modulators of α7 nicotinic acetylcholine receptors. | 08-30-2012 |
Eduardo Bertrand, Erlangen DE
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20090138098 | Method for Controlling a Modular Production Machine Consisting of Appliances and Components - Modular production machines with appliances and components, controlled by means of projects. A project is the establishment of an arrangement of appliances and modules. A plurality of machine objects is associated with the determined arrangement locations in the project. In this way, the projects have a variability in terms of different machine objects, which is enabled by an engineering system. A control system (a run-time system) can affect a corresponding selection from the options. To enable an economical control of production machines some appliances or components can be selectively replaced by other appliances or modules. | 05-28-2009 |
Eric Bertrand, Seignelay FR
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20160129141 | DECONTAMINATION DEVICE FOR MEDICAL MATERIAL - A decontamination device for medical material, including a support intended to receive and hold said medical material to be decontaminated on a predefined axis, a spraying means, a drying means and an irradiating means, wherein said spraying means is mounted in rotation about said predefined axis and in translation parallel to said predefined axis, in such a way that the spraying is directed towards said predefined axis, said drying means is mounted in translation parallel to said predefined axis, and said irradiating means is mounted in translation parallel to said predefined axis. | 05-12-2016 |
Eric Bertrand, Lot BE
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20090173254 | Bituminous glue - A bituminous glue for cold gluing of construction material and comprising an amount of non-polymerized oil, said glue comprises at least 35% by weight of bitumen, said glue further comprising clay and a dispersing agent, said amount of non-polymerized oil forming between 5 and 30% by weight of said glue and being not mixed with polymerized oil. | 07-09-2009 |
20100212546 | Bituminous cold glue - A bituminous cold glue for cold gluing of construction material and comprising at least 35% by weight of bitumen and at least 10% by weight of oil, and further comprising clay and a dispersing agent, said oil being a vegetable oil compound, based on a carbon chain comprising at least one of the C6 to C12 carbon atoms and further comprising between 0.1 and 5% by weight of a solvent. | 08-26-2010 |
20140024757 | WERKWIJZE VOOR HET VERVAARDIGEN VAN EEN BINDMIDDELSAMENSTELLING - Method for production of a binder compound wherein crude tall oil pitch is mixed with calcium hydroxide or calcium oxide, and wherein after mixing the crude tall oil pitch with the calcium hydroxide or calcium oxide, the mixture of crude tall oil pitch and calcium hydroxide or calcium oxide is allowed to react and then again further crude tall oil pitch and a polymer are added to the reacted mixture in order to obtain a base substance for the production of a roof covering membrane, a road surfacing material or a carpet backing. | 01-23-2014 |
Eric Bertrand, Perwez BE
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20090324960 | METHOD OF MANUFACTURING A BITUMINOUS MEMBRANE - Method of manufacturing a bituminous membrane provided with photovoltaic cells, according to which said photovoltaic cells are applied to one face of a reinforcement provided on the surface with an anti-exudation layer and in that next a bituminous mass is applied to the other face of said reinforcement. | 12-31-2009 |
20120041117 | Binder Compound - The present invention relates to a binder compound based on natural oil, polymer and resin. Such binder compounds can for example be used in roof covering membranes as an environmentally friendly alternative to bituminous roof covering membranes. | 02-16-2012 |
20120071597 | Membrane based on a binder compound with tall-oil pitch - Membrane based on a binder compound with tall-oil pitch Membrane produced on the basis of a binder compound comprising a crude tall-oil pitch in a quantity of 1-65 w. %, more specifically a quantity of 20-55 w. %, even more specifically a quantity of 36-55 w. %, and a polymer in a quantity of 7-40 w. %, more specifically in a quantity of 8-20 w. %, even more specifically in a quantity of 9-17 w. %, and a filler. | 03-22-2012 |
20130295282 | PROCESS FOR MANUFACTURING A WATERPROOFING MEMBRANE - The present invention relates to a process for manufacturing a waterproofing membrane comprising: | 11-07-2013 |
20140072765 | Unknown - Protective membrane, in particular a waterproofing or noise insulation membrane, based on mineral or vegetable bitumen, comprising a membrane body, and a first and second surface situated on either side of said membrane body, where the first surface comprises cork particles, characterised in that said particles have a granulometry of between 0.5 and 3 mm, preferably between 1 and 3 mm, and have been heat treated with steam. | 03-13-2014 |
20150051323 | BINDER COMPOUND - The present invention relates to a binder compound based on natural oil, polymer and resin. Such binder compounds can for example be used in roof covering membranes as an environmentally friendly alternative to bituminous roof covering membranes. | 02-19-2015 |
Eric Bertrand, Jouy En Josas FR
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20160121349 | ASSEMBLY FOR DISPENSING FLUID PRODUCT - A fluid dispenser assembly including a fluid dispenser having a reservoir forming a bottom wall. The dispenser assembly further includes a casing that surrounds the fluid dispenser at least in part, and that defines an insertion and extraction opening through which the fluid dispenser is insertable by sliding. The casing includes a blocker mechanism for blocking the dispenser in the casing, and an unblocker mechanism for de-activating the blocker mechanism so as to be able to extract the fluid dispenser from the casing by sliding. | 05-05-2016 |
Hugues Bertrand, Rioz FR
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20150093225 | DEVICE FOR ESTABLISHING A FLOAT CONDITION IN A HYDRAULICALLY SPRUNG LOADER LIFT CYLINDER ARRANGEMENT AFTER FLUID SUPPLY IS DECOUPLED - A front loader arrangement includes a hydraulically sprung lift cylinder arrangement coupled between opposite loader arm sides and respectively mounting masts. In order to permit the masts to pivot freely about their pivotal connections with the loader arm sides to aid the coupling of the masts to respective mounting frames fixed to a carrying vehicle, the hydraulic system in which the lift cylinder arrangement is incorporated includes a device, including a shut-off valve and an accumulator arrangement for establishing a float condition in the lift cylinder arrangement after a source of hydraulic fluid and associated control valve is decoupled by separating a hydraulic quick coupler. | 04-02-2015 |
20150093226 | ARRANGEMENT FOR EFFECTING FLOAT CONDITION IN LOADER HYDRAULIC LIFT CYLINDER AFTER HYDRAULIC FLUIDSUPPLY IS DECOUPLED - A front loader arrangement ( | 04-02-2015 |
Jay Aaron Bertrand, Villacortese IT
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20090136513 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS - A compound having formula (I): wherein: R, A, R | 05-28-2009 |
Jay Aaron Bertrand, Didcot, Oxfordshire GB
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20150299192 | SUBSTITUTED PYRIMIDINYL AND PYRIDINYL-PYRROLOPYRIDINONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS - The present invention relates to substituted pyrimidinyl- and pyridinylpyrrolopyridinone compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular RET family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions containing these compounds. | 10-22-2015 |
Jay Aaron Bertrand, Didcot GB
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20140155421 | SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASE INHIBITORS - The present invention relates to substituted pyrimidinyl-pyrrole compounds of formula (I) which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Janus kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them. | 06-05-2014 |
Jay Aaron Bertrand, West Hagbourne GB
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20140194406 | ALKYNYL SUBSTITUTED PYRIMIDINYL-PYRROLES ACTIVE AS KINASES INHIBITORS - The present invention relates to alkynyl substituted pyrimidinyl-pyrrole compounds which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity, in particular Jak and/or Src family kinases. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such compounds or the pharmaceutical compositions containing them. | 07-10-2014 |
Jay Aaron Bertrand, Villa Cortese (mi) IT
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20110281843 | SUBSTITUTED INDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS - Substituted indazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases associated with a deregulated protein kinase activity, like cancer. | 11-17-2011 |
20120157454 | ISOQUINOLIN-1 (2H) -ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 06-21-2012 |
20140045846 | ISOQUINOLIN-1(2H)-ONE DERIVATIVES AS PARP-1 INHIBITORS - There are provided substituted isoquinolin-1(2H)-one derivatives which selectively inhibit the activity of poly (ADP-ribose) polymerase PARP-1 with respect to poly (ADP-ribose) polymerase PARP-2. The compounds of the present invention are therefore useful in treating diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds. A screening method for the identification of compounds capable of binding several PARP proteins, as well the probes used in such method, are further objects of the invention. | 02-13-2014 |
Jean-Luc Bertrand, Orleans FR
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20160033052 | SERVO VALVE WITH DOUBLE MOBILE ASSEMBLY - Hydraulic servo valve ( | 02-04-2016 |
Jessica Bertrand, Osnabrueck DE
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20130324698 | ANTI-SYNDECAN-4 ANTIBODIES - The present invention relates to a recognition molecule against Syndecan-4, wherein said recognition molecule binds an epitope contained in an amino acid sequence corresponding to the amino acid sequence between amino acids 93 and 121 of the amino acid sequence shown in SEQ ID NO: 1 (FIG. | 12-05-2013 |
Laurent Bertrand, Twickenham Middlesex GB
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20120192213 | Delivering an Audio Video Asset - A method of delivering an audio video asset is described. The method includes: receiving an order specifying an audio video asset to be delivered and a delivery destination for the audio video asset, wherein a delivery destination represents one or more physical delivery recipients; determining delivery paths representing different delivery technologies that could be used to deliver the audio video asset to the delivery destination; retrieving a set of path capacity timelines for the delivery paths, wherein path capacity timelines in the set of path capacity timelines each model a quantity of available capacity varying over time; processing the path capacity timelines to yield delivery path capacities; applying an allocation algorithm to the delivery path capacities to yield candidate delivery allocations, wherein candidate delivery allocations each includes one or more time periods during which one or more time periods a defined quantity of capacity can be allocated for delivery of the audio video asset; applying a cost function to the candidate delivery allocations to yield cost values, wherein the cost values each represent a cost of delivering the audio video asset according to the candidate delivery allocations; calculating scores for the candidate delivery allocations in dependence on a cost value for that candidate delivery allocation and one or more other objectives; selecting a candidate delivery allocation having a lowest score to yield a selected candidate delivery allocation; and delivering the audio video asset according to the selected candidate delivery allocation. Related apparatus and methods are also described. | 07-26-2012 |
Laurent Bertrand, Twickenham GB
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20130268988 | Delivering an Audio Video Asset - Delivering an audio video asset in a way that makes best use of different delivery mechanisms available. | 10-10-2013 |
20150281763 | System and Method for Synchronized Presentation of Video Timeline Metadata - In one embodiment, a method for broadcast state agnostic timeline metadata presentation on a companion device is implemented on a computing device and includes: receiving timeline metadata associated with a video content item in a pseudo-live mode, where the timeline metadata is received from a timeline metadata provision system according to a timeline for an original broadcast of the video content item, and presenting the timeline metadata as it is received from said timeline metadata provision system, where the presenting is in parallel to an original or non-original broadcast of the video content item playing on an associated viewing device. | 10-01-2015 |
20150365710 | Synchronizing Broadcast Timeline Metadata - In one embodiment, a first content item having synchronization information, the first content item being a first instance of a reference content item, a candidate content item, which is a second instance of the reference content item, having synchronization information, a synchronizing processor which determines a synchronization point between the first content item and the candidate content item, on the basis of matching the synchronization information of the first content item and the candidate content item, a timeline metadata transmitter, which transmits stored timeline metadata to a device on which the first content item is playing, the transmission of the stored timeline metadata beginning from the synchronization point, wherein the stored timeline metadata includes timeline metadata that has been previously aggregated from earlier broadcasts of instances of the reference content item. Related systems, apparatus, and methods are also described. | 12-17-2015 |
Laurent Edmond Pierre Bertrand, Twickenham GB
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20150193497 | METHOD AND SYSTEM FOR ACQUISITION, NORMALIZATION, MATCHING, AND ENRICHMENT OF DATA - In one embodiment, a method includes obtaining a first data set from a first data source and a second data set from a second data source, the first data set including a first plurality of entities and the second data set including a second plurality of entities. The method also includes identifying a verified relationship between a first entity from the first plurality of entities and a second entity from the second plurality of entities and determining that a third entity from the first plurality of entities has a first same-as relationship with a fourth entity from the second plurality of entities based on one or more of the verified relationship or relationships between the first plurality of entities and the second plurality of entities. The method further includes generating first output data including the first same-as relationship. | 07-09-2015 |
Luc Bertrand, Orbais BE
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20140309171 | MARKER FOR BLOOD COAGULATION - The invention relates to the use of phosphorylated Acetyl-CoA carboxylase (ACC) in platelets from a subject as a biomarker for blood coagulation, preferably blood coagulation in the subject, preferably encompassing activation of the coagulation cascade as well as platelet activation, preferably thrombin-induced platelet activation. The invention encompasses uses and methods for the diagnosis or the monitoring of blood coagulation in the subject. The invention further relates to uses and methods for screening for anti-coagulants or pro-coagulants. | 10-16-2014 |
Mathieu Bertrand, Cergy Le Haut FR
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20150130383 | METHOD FOR DISCHARGING ENERGY STORED IN A STATOR OF AN ELECTRIC MOTOR - A method for discharging energy stored in a stator of an assisted steering electric motor of a motor vehicle is disclosed. The stator includes at least one electrical phase, where a state of disconnection of said phase with a control device of the stator is controlled by a switch device having at least one field effect transistor. The method involves keeping the field effect transistor in linear mode by controlling the voltage Vgs between the gate and the source of said transistor so as to keep the voltage Vds between the drain and the source of said transistor substantially equal to a reference voltage Vref. | 05-14-2015 |
Olivier Bertrand, Paris Cedex 15 FR
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20160083481 | FUSION PROTEINS AND IMMUNOCONJUGATES AND USES THEREOF - The present invention relates to isolated VHHs directed against human Glycophorin A. The present invention also relates to fusion proteins comprising the VHH according to the invention that is fused to at least one heterologous polypeptide and immunoconjugates comprising the VHH according to the invention that is conjugated to at least one chemical compound and their use in therapeutic or diagnostic methods. | 03-24-2016 |
Patrick Bertrand, Louvain-La-Neuve BE
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20100089616 | STRETCHABLE CONDUCTOR AND METHOD FOR PRODUCING THE SAME - The present invention relates to a compliant deformable conductor and a method for producing the same, comprising a wire or a tube made of an electrically insulating material and one or more electrical leads applied on said wire or tube, wherein one or more of said leads comprise a plurality of islets of conductive material, forming an electrically conductive layer providing electrical conduction and/or electrical percolation. | 04-15-2010 |
20120298530 | SMART SENSOR SYSTEM USING AN ELECTROACTIVE POLYMER - A system for measuring a solution pH includes a potentiostat with a working electrode made of an electro-conductive solid polymer transducer, an input to receive the potential to be applied between the working electrode and a reference electrode, and an output to transmit a signal representative of the current flowing between a counter electrode and the working electrode, the three electrodes being immerged into the solution. The system further includes a digital processor connected to a digital to analog converter for generating the potential to be applied between the working and the reference electrodes; and to an analog to digital converter for receiving a digital value representative of the current. The digital processor is adapted to modify the potential to maintain the current inside a predetermined range such that the potential is representative of the solution pH when the current is inside the predetermined range. | 11-29-2012 |
Paul Page Bertrand, Rosanna AU
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20150190366 | METHODS FOR INHIBITING NEURON APOPTOSIS AND NECROSIS - The present invention relates generally to methods for inhibiting neuron apoptosis and necrosis associated with excess glutamate release. | 07-09-2015 |
Sébastien Bertrand, Moulis-En-Medoc FR
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20100009143 | PROCESS FOR MANUFACTURING A PART MADE OF A CERAMIC MATRIX COMPOSITE CONTAINING MATRIX PHASES FOR HEALING AND DEFLECTING CRACKS - The method comprises the steps of: forming a porous fiber-reinforcing structure; introducing into the pores of the fiber structure powders containing elements for constituting the composite material matrix; and forming at least a main fraction of the matrix from said powders by causing a reaction to take place between said powders or between at least a portion of said powders and at least one delivered additional element; the powders introduced into the fiber structure and the delivered additional element(s) comprising elements that form at least one healing discontinuous matrix phase including a boron compound and at least one discontinuous matrix phase including a crack-deflecting compound of lamellar structure. At least a main fraction of the matrix is formed by chemical reaction between the powders introduced into the fiber structure and at least one delivered additional element, or by sintering the powders. | 01-14-2010 |
20120164430 | COMPOSITE MATERIAL PART HAVING A CERAMIC MATRIX, AND METHOD FOR MANUFACTURING SAME - In a composite material part having a ceramic matrix and including a fibrous reinforcement which is densified by a matrix consisting of a plurality of ceramic layers having a crack-diverting matrix interphase positioned between two adjacent ceramic matrix layers, the interphase includes a first phase made of a material capable of promoting the diversion of a crack reaching the interphase according to a first propagation mode in the transverse direction through one of the two ceramic matrix layers adjacent to the interphase, such that the propagation of the crack continues according to a second propagation mode along the interphase, and a second phase consisting of discrete contact pads that are distributed within the interphase and capable of promoting the diversion of the crack that propagates along the interphase according to the second propagation mode, such that the propagation of the crack is diverted and continues according to the first propagation mode through the other ceramic matrix layer that is adjacent to the interphase. | 06-28-2012 |
20120171375 | METHOD OF DENSIFYING THIN POROUS SUBSTRATES BY CHEMICAL VAPOR INFILTRATION, AND A LOADING DEVICE FOR SUCH SUBSTRATES - To densify thin porous substrates ( | 07-05-2012 |
Simone Bertrand, Frankfurt/main DE
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20150257520 | HEAD FOR AN ORAL CARE IMPLEMENT - A head for an oral care implement has a mounting surface and at least one tuft mounted thereon. The tuft has a longitudinal axis and a cross-sectional area extending in a plane perpendicular to the longitudinal axis. The tuft comprises a plurality of substantially cylindrical filaments. Each filament has a longitudinal axis and a cross-sectional area extending in a plane that is perpendicular to the longitudinal axis. The cross-sectional area of an individual filament has a substantially non-circular shape. The plurality of filaments is arranged such that the cross-sectional area of the tuft has a scaled-up shape of the individual filament's cross-sectional area. | 09-17-2015 |
Viviane Bertrand, Paris FR
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20160113867 | STABLE ORAL SOLUTIONS FOR COMBINED API - The present invention relates to a homogeneous, stable, and palatable pharmaceutical solution comprising baclofen, sorbitol and naltrexone. | 04-28-2016 |