Patent application number | Description | Published |
20110104394 | PROCESS FOR THE PERMANENT MULTICOLOR PAINTING OF A PRODUCT - A process for the permanent multicolor painting of a product, e.g. a body part, includes defining a first region, a first location within the first region and a second location within the first region but different from the first location, on the surface of the product. The surface is provided with a first release layer, at least in the first region and the first release layer is exposed to electromagnetic radiation, e.g. IR radiation, at the first location but not at the second location. The surface is provided with a first layer of paint at least at the first location. The first layer of paint is fixed, at least at the first location. Alternatively, the first release layer is applied at least at the second location but not at the first location, so that an exposure to electromagnetic energy at the first location can be omitted. | 05-05-2011 |
20110244143 | METHOD OF CREATING A FLUID LAYER IN THE SUBMICROMETER RANGE - A method of creating a fluid layer in the micrometer range includes transferring a fluid between substrates and forming a fluid layer. A surface energy of a first substrate releasing the fluid is higher than a surface energy of a fluid on the first substrate to create a first fluid deposit on the first substrate. A surface energy of a second substrate accepting the fluid is lower than a surface energy of a fluid on the second substrate to create a second fluid deposit on the second substrate that is reduced as compared to the first fluid deposit, A surface energy of a third substrate accepting the fluid is higher than a surface energy of a fluid on the third substrate to create a substantially homogeneous third fluid deposit on the third substrate that forms the fluid layer. | 10-06-2011 |
20120249679 | APPARATUS FOR PRINTING SURFACES HAVING A PLURALITY OF MOVABLE PRINT HEADS AND SYSTEM HAVING THE APPARATUS - An apparatus for printing surfaces, for example of three-dimensionally shaped vehicle body parts, includes movable print heads having actuable, preferably inkjet, nozzles, and at least one printing position and one parking position into which the print heads can be moved or rotated. At least one first and one second print head have mutually different nozzle configurations, sizes or shapes. In a first mode, the first print head is in a printing position and the second print head is in a parking position, and in a second mode, the first print head is in a parking position and the second print head is in a printing position. The print heads can be on a rotation apparatus which can be on a robot arm. Surfaces of any shape, having curvatures and/or undercuts, can be printed in one or multiple colors (in image terms). A system having the apparatus is also provided. | 10-04-2012 |
20120297999 | PRINTING METHOD AND OFFSET PRINTING UNIT - A printing method in a printing press includes zonally metering a printing ink at a first viscosity with a metering device and transferring the printing ink at a second viscosity with a printing form cylinder, in which the second viscosity is greater than the first viscosity. An offset printing unit for implementing the method is also provided. | 11-29-2012 |
20120316664 | METHOD FOR CREATING A FOLD PREPARATION PATTERN, COMPUTER FOR IMPLEMENTING THE METHOD AND SYSTEM HAVING THE COMPUTER - A method for creating a fold preparation pattern includes supplying job-specific signature characteristics to a computer and determining job-specific cutting requirements by using general cutting requirements assigned to respective general signature characteristics in the computer and using the job-specific signature characteristics. The computer accesses a database that contains cutting, trimming, and clipping patterns and compiles job-specific fold preparation patterns in accordance with the job-specific cutting requirements. A computer for implementing the method and a system having the computer are also provided. | 12-13-2012 |
20130257984 | SYSTEM FOR PRINTING ON AN OBJECT - A system for printing an image, preferably a multicolor halftone image, onto at least one non-planar area of a surface of an object, for example a section of a body of a vehicle, includes an inkjet print head having nozzles, a robot, preferably an articulated robot, creating a primary movement, the primary movement including at least two printing paths of the inkjet print head being lateral to each other, and a device creating a secondary movement, the secondary movement being substantially perpendicular to the primary movement and causing the printing paths to laterally adjoin each other. As a result, undesired streaks between the printing paths may advantageously be reduced or prevented. | 10-03-2013 |
20150042716 | METHOD AND SYSTEM FOR PRINTING AN OBJECT - A method prints an object, for example a vehicle and specifically the body thereof, wherein at least one area of the surface of the object is printed. The method includes: providing an image; three-dimensionally measuring at least the area; generating a number of spatial points in correspondence with the area; generating a three-dimensional net corresponding with the area; generating path data, i.e. a three-dimensional path for moving a robot for an inkjet printer head; generating raster data, i.e. a raster matrix, in particular a three-dimensional or higher raster matrix, for actuating the inkjet printer head; moving the robot, for example an articulated arm robot, utilizing the path data; and printing the image by the inkjet printer head utilizing the raster data. The method permits multi-color printing of any image onto so-called 3D surfaces of any shape. | 02-12-2015 |
20150097906 | METHOD FOR THE INDIRECT APPLICATION OF PRINTING LIQUID ONTO A PRINTING MATERIAL - A method for the indirect application of printing liquid onto a printing material provides an intermediate carrier, preferably a circulating belt, a liquid conditioning medium including a first substance applied onto the intermediate carrier and a printing liquid, in particular an inkjet ink, including a second substance applied onto the conditioning medium on the intermediate carrier. The printing liquid is situated as droplets or a layer substantially on the conditioning medium and the droplets or the layer form a contact region on their underside with the conditioning medium. The printing liquid is heated, preferably by way of a dryer and the printing liquid is transferred from the intermediate carrier onto the printing material. | 04-09-2015 |
Patent application number | Description | Published |
20130012546 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES - The present invention relates to hydroximoyl-tetrazole derivatives of formula (I), their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions. | 01-10-2013 |
20130040993 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES - The present invention relates to hydroximoyl-heterocycle derivatives, their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions. | 02-14-2013 |
20130045995 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES - The present invention relates to hydroximoyl-heterocycle derivatives of formula (I) | 02-21-2013 |
20130096311 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 1-ALKYLTETRAZOLYL OXIME DERIVATIVES - The present invention relates to a process for the preparation of 5-substituted 1-alkyltetrazolyl oxime derivatives. | 04-18-2013 |
20130102786 | PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 1-ALKYLTETRAZOLYL OXIME DERIVATIVES - The present invention relates to a process for the preparation of 5-substituted 1-alkyltetrazolyl oxime derivatives. | 04-25-2013 |
20130116287 | FUNGICIDE HYDROXIMOYL-HETEROCYCLES DERIVATIVES - The present invention relates to hydroximoyl-heterocycle derivatives of formula (I) | 05-09-2013 |
20130123305 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES - The present invention relates to hydroximoyl-tetrazole derivatives of formula (I), their process of preparation, their use as fungicide active agents, particularly in the form of fungicide compositions and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions. | 05-16-2013 |
Patent application number | Description | Published |
20130057093 | GENERATOR AND ACCESSORY GEARBOX DEVICE WITH A GENERATOR - The present invention proposes a generator for arrangement on a shaft of an accessory gearbox of an engine with a stator and with a rotor which can be coupled to a shaft of the accessory gearbox of the engine and which is rotatably mounted relative to the stator, where a stator area receiving the stator can be separated from a rotor area receiving the rotor. The rotor can be supplied with cooling medium in the rotor area. It furthermore proposes an accessory gearbox of an engine with a drive shaft operatively connectable to a main shaft of the engine and with at least one generator arranged on a shaft of the accessory gearbox. | 03-07-2013 |
20130098179 | ACCESSORY GEARBOX DEVICE FOR A JET ENGINE - The present invention proposes an accessory gearbox ( | 04-25-2013 |
20140026592 | ASSEMBLY FOR A JET ENGINE OF AN AIRCRAFT - The present invention proposes a structural unit for an aircraft engine having at least one fuel pump of a fuel circuit and at least one hydraulic fluid pump of a hydraulic fluid circuit, where the structural unit can be coupled to an accessory gearbox shaft of an accessory gearbox of the engine. | 01-30-2014 |
20140026700 | ACCESSORY GEARBOX DEVICE FOR A JET ENGINE - The present invention proposes an accessory gearbox for an engine having at least one accessory gearbox shaft connectable to an auxiliary unit and driveable by a drive shaft, said drive shaft being operatively connectable to an engine shaft of the engine. At least one auxiliary unit can be arranged on the drive shaft and/or in the area of the operative connection between the drive shaft and the engine shaft and/or on an accessory gearbox shaft connectable to a further auxiliary unit. | 01-30-2014 |
20150135660 | JET ENGINE COMPRISING A DEVICE FOR SPRAYING OIL INTO AN AIR-OIL VOLUME FLOW - The present invention describes a jet engine with a device for spraying oil into an air-oil volume flow guided inside a flow cross-section limited by a wall area. The air-oil volume flow is guidable through an oil separator in order to separate the oil. In accordance with the invention, the oil can be sprayed into the air-oil volume flow in the area of the device via an outlet area designed movable relative to the wall area. | 05-21-2015 |
20150135663 | JET ENGINE COMPRISING A DEVICE FOR SPRAYING OIL - The present invention describes a jet engine with a device for spraying oil into an air-oil volume flow guided inside a flow cross-section limited by a wall area. The air-oil volume flow is guidable through an oil separator in order to separate the oil. In accordance with the invention, the oil can be sprayed into the air-oil volume flow in the area of the device via an outlet area rigidly connected to the wall area. | 05-21-2015 |
20150176447 | JET ENGINE DEVICE WITH AT LEAST ONE COMPONENT THAT IS ARRANGED IN A CASING AND THAT IS ROTATABLE TO THE CASING - The present invention describes a device of a jet engine with at least one component arranged in a casing and designed rotatable relative to said casing. At least one air-oil volume flow can be passed out of an area of the jet engine into the casing. In accordance with the invention the air-oil volume flow can be introduced into the casing via an introducing facility at least approximately tangentially to an area of the rotatable component close to at least an outer circumferential area. | 06-25-2015 |
20150321130 | DEVICE OF AN AIRCRAFT ENGINE FOR SEPARATING OIL FROM AN AIR-OIL VOLUME FLOW - A device of an aircraft engine for separating oil from an air-oil volume flow and an apparatus for introducing oil into the air-oil volume flow. An outlet area of the apparatus for introducing oil is provided in a closed line section, into which the air-oil volume flow can be introduced via an inlet area. In accordance with the invention, a flow cross-section of the line section downstream of the outlet area of the apparatus tapers at least partially like a nozzle and at least in some sections inside a confusor area. | 11-12-2015 |
Patent application number | Description | Published |
20110127357 | ELECTROMAGNETIC VALVE FOR CONTROLLING AN INJECTOR OR FOR REGULATING PRESSURE OF A HIGH-PRESSURE FUEL ACCUMULATOR - Electromagnetic valve, particularly for controlling a fuel injector or for regulating the pressure of a high-pressure fuel accumulator, comprising a casing ( | 06-02-2011 |
20120325936 | FUEL INJECTOR - The invention relates to a control chamber ( | 12-27-2012 |
20130240639 | FUEL INJECTOR - The invention relates to a fuel injector for injecting fuel into the combustion chamber of an internal combustion engine, comprising a nozzle needle ( | 09-19-2013 |
20130257439 | METHOD FOR OPERATING A SWITCHING ELEMENT - A method is described for operating at least one magnetic switching element, at least one first connection of at least one sensor device being connected to at least one connection of a coil of the magnetic switching element, and the first connection or an additional connection of the sensor device being connected to a reference potential, and a measuring state being established in which at least one connection of the coil is essentially at least temporarily decoupled from the reference potential and/or from a source activating the coil, and at least one signal of at least one sensor of the sensor device being ascertained in the measuring state from at least one electrical potential at at least one connection of the coil. | 10-03-2013 |
20130300422 | METHOD FOR OPERATING A MAGNETIC SWITCHING ELEMENT - In a method for operating a magnetic switching element, at least one connection of at least one sensor device is connected to at least one connection of a coil of the magnetic switching element, and at least one measuring state is established in which the at least one connection of the coil is largely at least temporarily decoupled from a ground, a voltage source, and/or a current source activating the coil, and at least one auxiliary voltage and/or at least one auxiliary current is/are applied to the at least one connection of the coil in the measuring state, and at least one sensor signal is ascertained from at least one electrical potential, at least one potential difference, and/or at least one current flowing at the connections of the coil. | 11-14-2013 |
20130312709 | METHOD FOR OPERATING A FUEL INJECTION SYSTEM OF AN INTERNAL COMBUSTION ENGINE - A method for operating a fuel injection system of an internal combustion engine is described. The fuel injection system has an injector for metering fuel into a combustion chamber of the internal combustion engine. The injector has an actuator, a control valve and a nozzle needle. In the method, the actuator is supplied a voltage and/or a current during an activation period. The control valve is set into a lifting motion by the actuator. The injector is opened and closed by the nozzle needle, using the lifting motion of the control valve. A further time period is ascertained. The further time period ends at the closing time of the nozzle needle. A function is ascertained, which links the activation period to the further time period. A shortest activation period, for which the nozzle needle opens and produces an injection, is ascertained with the aid of the function. An opening delay period (d | 11-28-2013 |
20140027534 | FUEL INJECTOR - The invention relates to a fuel injector for a fuel injection system, in particular a common rail injection system, comprising a jet needle ( | 01-30-2014 |
Patent application number | Description | Published |
20100216648 | SYNTHESIS OF SEQUENCE-VERIFIED NUCLEIC ACIDS - The invention relates to methods and devices for preparing synthetic nucleic acids. | 08-26-2010 |
20110092380 | IMPROVED MOLECULAR-BIOLOGICAL PROCESSING EQUIPMENT - The invention relates to improved molecular-biological processing equipment and an improved method of processing biological samples. The invention combines the provision of biologically functional molecules such as nucleic acids and peptides and of derivatives or analogs of these two classes of molecules in miniaturized flow cells with the sequential addition of reagents or fluids and serves for the processing of biological samples, such as proteins, nucleic acids, biogenic small molecules such as e.g. metabolites, viruses or cells, which for this purpose are introduced into the miniaturized flow cells. The invention further relates to methods and to the use of the molecular-biological processing equipment according to the invention for the detection and/or for the isolation of nucleic acids; for sequencing; for point mutation analysis; for the analysis of genomes and/or chromosomes; for the production of synthetic nucleic acids; for the production of arrays of primers, probes and/or antisense molecules; and other analytical and synthetic methods. | 04-21-2011 |
20120045771 | METHOD FOR ANALYSIS OF NUCLEIC ACID POPULATIONS - The invention relates to a method for isolation of target molecules from a nucleic acid population. | 02-23-2012 |
20120071327 | INDEXING OF NUCLEIC ACID POPULATIONS - The invention relates to a method for acquisition of genetic information, in particular for personalized medicine. | 03-22-2012 |
20120108462 | MIRNA FINGERPRINT IN THE DIAGNOSIS OF LUNG CANCER - The present invention provides novel methods for diagnosing diseases based on the determination of specific miRNAs that have altered expression levels in disease states compared to healthy controls. | 05-03-2012 |
20120157336 | miRNA FINGERPRINT IN THE DIAGNOSIS OF DISEASES - The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 06-21-2012 |
20120157337 | miRNA FINGERPRINT IN THE DIAGNOSIS OF MULTIPLE SCLEROSIS - The present invention provides novel methods for diagnosing diseases based on the determination of specific miR-NAs that have altered expression levels in disease states compared to healthy controls. | 06-21-2012 |
20120309645 | miRNA IN THE DIAGNOSIS OF OVARIAN CANCER - The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 12-06-2012 |
20130035251 | miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 02-07-2013 |
20130157883 | Complex miRNA Sets as Novel Biomarkers for an Acute Coronary Syndrome - The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of an acute coronary syndrome in a blood sample from a human. Further, the present invention relates to means for diagnosing and/or prognosing of an acute coronary syndrome comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of an acute coronary syndrome based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome compared to a reference. In addition, the present invention relates to a kit for diagnosing and/or prognosing of an acute coronary syndrome comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for an acute coronary syndrome and at least one reference. | 06-20-2013 |
20130331278 | COMPLEX SET OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR PROSTATE DISEASES - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of prostate diseases in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of prostate diseases in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of prostate diseases in a body fluid sample from a subject. | 12-12-2013 |
20130331290 | COMPLEX MIRNA SETS AS NOVEL BIOMARKERS FOR LUNG DISEASES - The present invention relates to single polynucleotides or sets of polynucleotides for detecting single miRNAs or sets of miRNAs for diagnosing and/or prognosing of a lung disease in a biological sample from a patient. Further, the present invention relates to means for diagnosing and/or prognosing of a lung disease comprising said polynucleotides or sets of polynucleotides. Furthermore, the present invention relates to a method for diagnosing and/or prognosing of a lung disease based on the determination of expression profiles of single miRNAs or sets of miRNAs representative for a lung disease. In addition, the present invention relates to a kit for diagnosing and/or prognosing of a lung disease comprising means for determining expression profiles of single miRNAs or sets of miRNAs representative for a lung disease and optionally at least one reference and/or algorithm or mathematical function comprised on at least one data carrier. | 12-12-2013 |
20140024554 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR GLIOBLASTOMA - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of glioblastoma in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of glioblastoma in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of glioblastoma in a body fluid sample from a subject. | 01-23-2014 |
20140193822 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR KIDNEY CANCER - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of kidney cancer in a body fluid sample from a subject. | 07-10-2014 |
20140194312 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR DILATED CARDIOMYOPATHY - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of dilated cardiomyopathy in a body fluid sample from a subject. | 07-10-2014 |
20140213476 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR COLON CANCER - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of colon cancer in a body fluid sample from a subject. | 07-31-2014 |
20140274789 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR PSORIASIS - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of psoriasis in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of psoriasis in a body fluid sample from a subject. In addition, the present invention relates to sets of miRNAs for diagnosing and/or prognosing of psoriasis in a body fluid sample from a subject. | 09-18-2014 |
20150031777 | miRNA FINGERPRINT IN THE DIAGNOSIS OF WILMS' TUMOUR - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 01-29-2015 |
20150037327 | miRNA based treatment monitoring in multiple sclerosis - The present invention relates to methods of determining whether a patient responds to a therapeutic treatment of multiple sclerosis (MS), of monitoring the course of multiple sclerosis (MS) in a patient, of determining the risk for a relapse of multiple sclerosis (MS) in a patient, and of adjusting the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient. Said methods are based on the determination of the level of at least one miRNA in a test sample isolated from the patient. The present invention also relates to a method of identifying a compound suitable for the treatment of multiple sclerosis in a patient. Further, the present invention relates to the use of a polynucleotide or a polynucleotide set for detecting a miRNA to determine whether a patient responds to a therapeutic treatment of multiple sclerosis, to monitor the course of multiple sclerosis in a patient, to determine the risk of a relapse of multiple sclerosis in a patient, to adjust the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient, and to identify a compound suitable for the treatment of multiple sclerosis in a patient. Furthermore, the present invention relates to a kit for determining whether a patient responds to a therapeutic treatment of multiple sclerosis, for monitoring the course of multiple sclerosis in a patient, for determining the risk of a relapse of multiple sclerosis in a patient, for adjusting the dose of a therapeutic drug applied for therapeutic treatment of multiple sclerosis in a patient, or for identifying a compound suitable for the treatment of multiple sclerosis in a patient comprising means for determining the level of at least one miRNA in a test sample isolated from a patient. | 02-05-2015 |
20150045243 | MIRNAS AS NON-INVASIVE BIOMARKERS FOR DIAGNOSIS - The present invention relates to non-invasive methods, kits and means for diagnosing and/or prognosing of a disease in a body fluid sample from a subject. Further, the present invention relates to set of polynucleotides or sets of primer pairs for detecting sets of miRNAs for diagnosing and/or prognosing of a disease in a body fluid sample from a subject. | 02-12-2015 |
20150064704 | COMPLEX SETS OF MIRNAS AS NON-INVASIVE BIOMARKERS FOR EARLY DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION - The present invention relates to non-invasive methods for early diagnosis and/or differential diagnosis of acute myocardial infarction in a blood sample of a subject. Further, the present invention relates to polynucleotides or sets of polynucleotides for detecting miRNAs or sets of miRNAs for early diagnosis and/or differential diagnosis of acute myocardial infarction in a blood sample of a subject. | 03-05-2015 |
20150292020 | miRNA Fingerprint in the Diagnosis of COPD - MicroRNAs (miRNA) are a recently discovered class of small non-coding RNAs (17-14 nucleotides). Due to their function as regulators of gene expression they play a critical role both in physiological and in pathological processes, such as cancer. The present invention provides novel methods for diagnosing a state of health based on the determination of specific miRNAs that have altered expression levels in different conditions, e.g. disease states compared to healthy controls. | 10-15-2015 |
Patent application number | Description | Published |
20080206201 | Recombinant Newcastle Disease Virus - The goal of the invention is to increase the therapeutical activity of oncolytic NDV. This issue is solved by a Newcastle Disease Virus comprising a recombinant nucleic acid, wherein the nucleic acid codes for a binding protein that has a therapeutic activity when expressed by the virus-infected tumor cell. Binding proteins belong to the following group: A natural ligand or a genetically modified ligand, a recombinant soluble domain of a natural receptor or a modified version of it, a peptide-ligand, an antibody molecule and derivatives thereof or antibody-like molecules like ankyrin repeat molecules or derivatives thereof. | 08-28-2008 |
20090208495 | ANTI-TUMOR EFFECTIVE PARAMYXOVIRUS - Paramyxovirus from the group APMV3, APMV4, APMV5, APMV6, APMV7, APMV8, APMV9, Mapueravirus and Fer-de-Lance virus are described, which can be used for the production of a medicament for the treatment of tumors. The virus has a selectivity to kill human tumor cells but not human normal differentiated and human normal proliferating cells at the same dose. By genetic engineering the virus can be modified in such a way that one or more genes are added or are replaced by the homologous genes of a related paramyxovirus. By that method the anti-tumor activity of the resulting chimeric virus is enhanced compared to the parental virus. | 08-20-2009 |
20100092430 | ATTENUATED ONCOLYTIC PARAMYXOVIRUSES ENCODING AVIAN CYTOKINES - The invention refers to a recombinant oncolytic RNA Newcastle Disease Virus for the treatment of a proliferative disease, comprising at least one transgene coding for an avian cytokine, wherein the recombinant oncolytic RNA Newcastle Disease Virus is obtainable from a velogenic or mesogenic oncolytic RNA Newcastle Disease Virus. Virus-mediated expression of the cytokine in the natural host cells leads to a reduced pathogenicity of the virus for avian species. Furthermore the virus genome can encode binding proteins, prodrug-converting enzymes or/and proteases. The selective expression of these molecules in virus-infected tumor cells increases the anti-tumor effect of the virus. | 04-15-2010 |
20110020282 | RECOMBINANT NEWCASTLE DISEASE VIRUS - The goal of the invention is to increase the therapeutical activity of oncolytic NDV. This issue is solved by a Newcastle Disease Virus comprising a recombinant nucleic acid, wherein the nucleic acid codes for a binding protein that has a therapeutic activity when expressed by the virus-infected tumor cell. Binding proteins belong to the following group: A natural ligand or a genetically modified ligand, a recombinant soluble domain of a natural receptor or a modified version of it, a peptide-ligand, an antibody molecule and derivatives thereof or antibody-like molecules like ankyrin repeat molecules or derivatives thereof. | 01-27-2011 |
20130066055 | NEW BINDER-DRUG CONJUGATES (ADCS) AND USE THEREOF - The present application relates to new binder-drug conjugates (ADCs) of N,N-dialkylauristatins that are directed against the target C4.4a, to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for treating and/or preventing illnesses, and also to the use of these ADCs for producing medicaments for treating and/or preventing illnesses, more particularly hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures. | 03-14-2013 |
20130122024 | NEW BINDER-DRUG CONJUGATES (ADCS) AND USE THEREOF - The present application relates to new binder-drug conjugates (ADCs) of N,N-dialkylauristatins that are directed against the target mesothelin, to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for treating and/or preventing illnesses, and also to the use of these ADCs for producing medicaments for treating and/or preventing illnesses, more particularly hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures. | 05-16-2013 |
20140127240 | Novel Binder-Drug Conjugates (ADCs) and Use of Same - The present patent application relates to novel binder-drug conjugates (ADCs) of N,N-dialkylauristatins directed against the target epidermal growth factor receptor (EGFR, gene ID 1956), effective metabolites of these ADCs, methods for producing these ADCs, use of these ADCs for treatment and or prevention of diseases as well as the use of these ADCs to produce pharmaceutical drugs for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as cancer, for example. Such treatments may be administered as monotherapy or in combination with other pharmaceutical drugs or other therapeutic measures. | 05-08-2014 |
20150030618 | NOVEL BINDER-DRUG CONJUGATES (ADCS) AND USE THEREOF - The present application relates to new binder-drug conjugates (ADCs) of N,N-dialkylauristatins that are directed against the target C4.4a, to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for treating and/or preventing illnesses, and also to the use of these ADCs for producing medicaments for treating and/or preventing illnesses, more particularly hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures. | 01-29-2015 |
20150246136 | NOVEL BINDER-DRUG CONJUGATES (ADCs) AND USE OF SAME - The present patent application relates to novel binder-drug conjugates (ADCs) of N,N-dialkylauristatins directed against the target epidermal growth factor receptor (EGFR, gene ID 1956), effective metabolites of these ADCs, methods for producing these ADCs, use of these ADCs for treatment and or prevention of diseases as well as the use of these ADCs to produce pharmaceutical drugs for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic diseases such as cancer, for example. Such treatments may be administered as monotherapy or in combination with other pharmaceutical drugs or other therapeutic measures. | 09-03-2015 |
Patent application number | Description | Published |
20080248707 | Armor material and method for producing it - The invention is based on the object of providing armoring that is lightweight and exhibits a denser microstructure that is improved as against ceramic composite materials. To this end, armoring against high dynamic impulsive loads is provided that comprises a composite material having at least two phases, the first phase forming a matrix for the second phase, and the first phase being a glass or a glass ceramic, and the second phase being embedded and distributed in the form of particles and/or fibers in the matrix formed by the material of the first phase. | 10-09-2008 |
20080304788 | Broadband Light Source Having a Microstructured Optical Fiber for Endoscopic and Fluorescence Microscopic Examination Devices, in Particular for Special Devices for Optical Biopsy - The invention relates to an arrangement for generating a broadband spectrum that can be used in particular as a light source for short coherence interferometry and confocal microscopy as well as endoscopic short coherence interferometry and endoscopic confocal microscopy. The arrangement comprises a laser, in particular a laser diode, for generating a short light pulse of wavelength λ | 12-11-2008 |
20090156384 | ARMOR MATERIAL MADE OF GLASS CERAMICS - The invention relates to a glass ceramic armour material consisting (in % by weight in relation to oxide base) of 5-33 SiO | 06-18-2009 |
20110159760 | Armor material and method for producing it - The invention is based on the object of providing armoring that is lightweight and exhibits a denser microstructure that is improved as against ceramic composite materials. To this end, armoring against high dynamic impulsive loads is provided that comprises a composite material having at least two phases, the first phase forming a matrix for the second phase, and the first phase being a glass or a glass ceramic, and the second phase being embedded and distributed in the form of particles and/or fibers in the matrix formed by the material of the first phase. | 06-30-2011 |
20130136981 | COMPONENTS FOR BATTERY CELLS WITH INORGANIC CONSTITUENTS OF LOW THERMAL CONDUCTIVITY - A lithium-ion battery cell is provided that includes at least one inorganic, multi-functional constituent that has a low thermal conductivity and is suitable for reducing or restricting thermal anomalies at least locally. | 05-30-2013 |
20130186140 | LITHIUM ALUMINOSILICATE GLASS WITH HIGH MODULUS OF ELASTICITY, AND METHOD FOR PRODUCING SAME - A lithium aluminosilicate glass and a method for producing such lithium aluminosilicate glass are provided. The glass has a composition, in mol %, of: SiO | 07-25-2013 |
20130316218 | ELECTROCHEMICAL ENERGY ACCUMULATOR - A glass-based material is disclosed, which is suitable for the production of a separator for an electrochemical energy accumulator, in particular for a lithium ion accumulator, wherein the glass-based material comprises at least the following constituents (in wt.-% based on oxide): SiO | 11-28-2013 |
20140171901 | DEVICE FOR RETAINING AND STORING LIQUID MEDIA AND METHOD OF EXPELLING THE LIQUID MEDIA - A device for retaining and storing a liquid medium, such as medication, includes a syringe body, a retention and/or storage container, consisting essentially of a glass material, a closure element for the retention and/or storage container consisting essentially of a rubber elastic material, and at least one needle. The retention and/or storage container is a vial having a solid bottom and a pushing device is provided to move the vial in a substantially axial direction in the syringe body, the pushing device acting upon the solid bottom of the vial. | 06-19-2014 |
20140209581 | LIGHT CONCENTRATOR OR DISTRIBUTOR - A light concentrator or distributor is provided, which includes a plurality of light conducting cells that are lined up in a transparent light conducting body. The light conducting cells are defined by boundary faces, which are produced within the light conducting body using laser radiation. | 07-31-2014 |
20150070907 | OPTICAL CONVERTER FOR HIGH LUMINANCES - An optical converter for producing colored or white light from blue excitation light is provided. The converter has good scattering properties to be able to produce nearly white light from the scattered blue light components and the scattered, converted yellow light components. The optical converter includes material including one or more of a YAG ceramic, a LuAG ceramic, and a magnesium-aluminum ceramic exhibiting strong scattering. | 03-12-2015 |
20150285595 | PROTECTIVE GLAZING COMPRISING TRANSPARENT CERAMICS - Armored glasses for windows in all kinds of vehicles, aircraft, missiles of all types, marine and underwater vehicles of all types and/or buildings and manufacturing methods are provided. The armored glass is a composite having at least one opto-ceramic layer having a front side and a rear side and a film of a transparent material disposed on the front and/or rear side of the opto-ceramic layer and integrally connected to the opto-ceramic layer so that the transparency of the composite is greater than the transparency of the opto-ceramic layer alone. The film of the transparent material renders roughnesses of the front and/or rear side of the opto-ceramic layer substantially optically ineffective. | 10-08-2015 |