| Patent application number | Description | Published |
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| 20080286828 | MATERIALS AND METHODS RELATING TO G-PROTEIN COUPLED RECEPTOR OLIGOMERS - The invention provides materials and methods relating to G-protein coupled receptor (GPCR) oligomers. Complexes of two or more GPCRs associated with G-proteins are provided. Also provided are fusion proteins comprising a GPCR and a G-protein, nucleic acids, expression vectors and host cells. Methods of producing the complexes and fusion proteins of the invention are also provided. | 11-20-2008 |
| 20110177612 | Human G Protein-Coupled Receptors and Modulators Thereof for the Treatment of Metabolic-Related Disorders - The present invention relates to methods of identifying whether a candidate compound is a modulator of a G protein-coupled receptor (GPCR). In preferred embodiments, the GPCR is human. In other preferred embodiments, the GPCR is coupled to Gi and lowers the level of intracellular cAMP. In other preferred embodiments, the GPCR is expressed endogenously by adipocytes. In further preferred embodiments, the GPCR inhibits intracellular lipolysis. In other further preferred embodiments, the GPCR is a nicotinic acid receptor. The present invention also relates to methods of using a modulator of said GPCR. Preferred modulator is agonist. Agonists of the invention are useful as therapeutic agents for the prevention or treatment of metabolic-related disorders, including dyslipidemia, atherosclerosis, coronary heart disease, stroke, insulin resistance, and type 2 diabetes. | 07-21-2011 |
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| 20090076254 | NON-ENDOGENOUS, CONSTITUTIVELY ACTIVATED HUMAN SEROTONIN RECEPTORS AND SMALL MOLECULE MODULATORS THEREOF - Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT | 03-19-2009 |
| 20090197868 | 5ht2c receptor modulator compositions and methods of use - The present invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist. In addition, the invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist having Formula (I): or a pharmaceutically acceptable salt, solvate or hydrate thereof. These compositions are useful in pharmaceutical compositions whose use includes the treatment of obesity. | 08-06-2009 |
| 20130217677 | 5HT2C RECEPTOR MODULATOR COMPOSITIONS AND METHODS OF USE - The present invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist. In addition, the invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist having Formula (I): or a pharmaceutically acceptable salt, solvate or hydrate thereof. These compositions are useful in pharmaceutical compositions whose use includes the treatment of obesity. | 08-22-2013 |
| 20150087634 | 5HT2C RECEPTOR MODULATOR COMPOSITIONS - The present invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist. In addition, the invention relates to a composition comprising phentermine and a selective 5HT-2C receptor agonist having Formula (I): | 03-26-2015 |
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| 20140373397 | PLOW FOR USE WITH AUTOMOBILE - A personal use plow for pushing, but not limited to, snow and slush from ones driveway by most passenger automobiles and/or ATV's that is attached using a unique strapping and cog bracing system. The plow is made of injected molded structural foam plastic and comes in 5 separate panels that can be easily assembled into a solid plow blade. This material is lightweight and allows for easy transportation, storage, and use. When assembled, the plow can be used either in the front or back of the vehicle. The plow attaches to the vehicle by a special hook, designed as part of this patent, which attaches to the hood, trunk, or luggage rack of the vehicle. All parts for the functionality of the plow are contained on the plow itself, so there are no brackets or hitches required to be attached to the bumpers or vehicle. | 12-25-2014 |
| 20150284929 | SHOVEL ASSEMBLY ADN METHOD OF ASSEMBLY THEREOF - The present disclosure relates to a shovel assembly for use in association with snow, sand, or any other particulate matter for collection and cleaning residing on a flat horizontal surface such as the ground, more specifically the shovel assembly and a method of assembly and use thereof in which the shovel's blade is made of multiple interlocked sections, each having opposite top and bottom edges with different geometries adapted for different purposes, an adjustable composite handle with multiple grips for adaptation to varied user preferences and a dynamic pivot at the base of the handle to easily change the blade's push angle during use. | 10-08-2015 |
| Patent application number | Description | Published |
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| 20140373397 | PLOW FOR USE WITH AUTOMOBILE - A personal use plow for pushing, but not limited to, snow and slush from ones driveway by most passenger automobiles and/or ATV's that is attached using a unique strapping and cog bracing system. The plow is made of injected molded structural foam plastic and comes in 5 separate panels that can be easily assembled into a solid plow blade. This material is lightweight and allows for easy transportation, storage, and use. When assembled, the plow can be used either in the front or back of the vehicle. The plow attaches to the vehicle by a special hook, designed as part of this patent, which attaches to the hood, trunk, or luggage rack of the vehicle. All parts for the functionality of the plow are contained on the plow itself, so there are no brackets or hitches required to be attached to the bumpers or vehicle. | 12-25-2014 |
| 20150284929 | SHOVEL ASSEMBLY ADN METHOD OF ASSEMBLY THEREOF - The present disclosure relates to a shovel assembly for use in association with snow, sand, or any other particulate matter for collection and cleaning residing on a flat horizontal surface such as the ground, more specifically the shovel assembly and a method of assembly and use thereof in which the shovel's blade is made of multiple interlocked sections, each having opposite top and bottom edges with different geometries adapted for different purposes, an adjustable composite handle with multiple grips for adaptation to varied user preferences and a dynamic pivot at the base of the handle to easily change the blade's push angle during use. | 10-08-2015 |
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| 20140145794 | POWER COMBINER - A power combining apparatus includes an output waveguide section having inner and outer coaxial conductors, wherein an outer surface of the inner conductor and an inner surface of the outer conductor each includes a substantially linear taper, a center waveguide section having an input, an output, and a plurality of antenna elements, the output of the center waveguide section being coupled to the output waveguide section, and an output waveguide section coupled to the output of the center waveguide section. A power combining apparatus includes an output waveguide section having a central longitudinal axis, and inner and outer coaxial conductors configured to maintain a substantially constant characteristic impedance along the central longitudinal axis, a center waveguide section having an input, an output, and a plurality of antenna elements, the output of the center waveguide section being coupled to the output waveguide section, and an input waveguide section coupled to the input of the center waveguide section. | 05-29-2014 |
| 20140145795 | POWER COMBINER USING TRI-PLANE ANTENNAS - A power combining apparatus includes a waveguide structure and a plurality of antenna elements arranged in the waveguide structure, wherein each of the antenna elements comprises a center planar antenna layer, two outer planar antenna layers arranged on opposite sides of the center planar antenna layer, a non-conductive layer between the center planar antenna layer and one of the outer planar antenna layers, and another non-conductive layer between the center planar antenna and the other one of the outer planar antenna layers. The power combining apparatus includes a waveguide structure having an input, an output, and a plurality of antenna elements arranged in the waveguide structure, wherein each antenna element is configured to transform an electric field direction of an electromagnetic field by substantially 90 degrees rotation about a longitudinal axis of the waveguide structure, wherein a bandwidth of the antenna is less than, equal to, or greater than a decade of frequency range. | 05-29-2014 |
| 20140167880 | PASSIVE COAXIAL POWER SPLITTER/COMBINER - A passive coaxial signal power splitter apparatus includes an input port, an input coaxial waveguide section coupled to the input port, a guided wave structure coupled to the input coaxial waveguide section, a plurality of antenna elements arranged in the guided wave structure, and an output port coupled to each of the antenna elements. A passive coaxial signal power combiner includes a plurality of input ports, a guided wave structure coupled to the plurality of input ports, a plurality of antenna elements in the guided wave structure, wherein each antenna element is coupled to one or more of the input ports, a coaxial waveguide section coupled to the guided wave structure, and an output port coupled to the coaxial waveguide section. | 06-19-2014 |
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| 20090037138 | Methods, Systems and Formats for Data, Such as Data Used in Laser Projection of Fasteners Used in Manufacturing - A system and method provides data for a laser projection process used in manufacturing involving fasteners. For example, the laser projection process may include projecting a laser image associated with fasteners used to assemble objects. Fastener attribute data may be extracted from an engineer's design data and processed to generate a laser projection output file. This output file may include geometric data used to project a laser image associated with the fasteners. For example, this image may be an outline indicating the location, shape, and orientation of a fastener. The output file may also include non-geometric data associated with attributes of the objects to be assembled. Both the geometric and the non-geometric data can then be displayed in a user interface, such as a display screen of a laser projector control device, in addition to the display of the laser image in three-dimensional space. | 02-05-2009 |
| 20120004752 | METHODS, SYSTEMS, AND FORMATS FOR DATA, SUCH AS DATA USED IN LASER PROJECTION OF FASTENERS USED IN MANUFACTURING - A system and method provides data for a laser projection process used in manufacturing involving fasteners. For example, the laser projection process may include projecting a laser image associated with fasteners used to assemble objects. Fastener attribute data may be extracted from an engineer's design data and processed to generate a laser projection output file. This output file may include geometric data used to project a laser image associated with the fasteners. For example, this image may be an outline indicating the location, shape, and orientation of a fastener. The output file may also include non-geometric data associated with attributes of the objects to be assembled. Both the geometric and the non-geometric data can then be displayed in a user interface, such as a display screen of a laser projector control device, in addition to the display of the laser image in three-dimensional space. | 01-05-2012 |
| 20130203511 | METHODS, SYSTEMS, AND FORMATS FOR DATA, SUCH AS DATA USED IN LASER PROJECTION OF FASTENERS USED IN MANUFACTURING - A system and method provides data for a laser projection process used in manufacturing involving fasteners. For example, the laser projection process may include projecting a laser image associated with fasteners used to assemble objects. Fastener attribute data may be extracted from an engineer's design data and processed to generate a laser projection output file. This output file may include geometric data used to project a laser image associated with the fasteners. For example, this image may be an outline indicating the location, shape, and orientation of a fastener. The output file may also include non-geometric data associated with attributes of the objects to be assembled. Both the geometric and the non-geometric data can then be displayed in a user interface, such as a display screen of a laser projector control device, in addition to the display of the laser image in three-dimensional space. | 08-08-2013 |
