Patent application number | Description | Published |
20160032404 | BIOMARKERS FOR PREDICTING RESPONSE OF DLBCL TO TREATMENT WITH A BTK INHIBITOR - Disclosed herein, are methods, systems, compositions, arrays, and kits for using biomarkers, biomarker genes (e.g. EP300, MLL2, BCL-2, RB1, LRP1B, PIM1, TSC2, TNFRSF11A, SMAD4, PAX5, CARD11, ACTG2, LOR, GAPT, CCND2, SELL, GEN1, HDAC9, CD79B, MYD88, and ROS1) or biomarker gene expression levels for stratifying a patient having a hematological malignancy such as DLBCL for treatment, and administering a TEC inhibitor to selected patients. Also disclosed herein are methods, systems, compositions, arrays, and kits for using biomarkers, biomarker genes, or biomarker gene expression levels for monitoring a patient during treatment of a hematological malignancy such as DLBCL or FL or for optimizing a treatment regimen with a TEC inhibitor. | 02-04-2016 |
Patent application number | Description | Published |
20130232194 | EVENT APPLICATION - A system, method, and article of manufacture provide the ability to manage event-based information/content. A client application uploads information about an event to an event application executing on a server. The event application manages information for an event site that corresponds to an event that multiple persons attend and is an electronic representation of the event. The event application receives the uploaded information and manages client access to the uploaded information. | 09-05-2013 |
20130268479 | SYSTEM AND METHOD FOR PRESENTING AND MANAGING SOCIAL MEDIA - A method, system, apparatus, and computer program product provide the ability to present media content on a social media network. Live streaming data is received from multiple data sources. The data is enriched with meta information using internal systems via application programming interfaces (APIs). The live streamed data is transformed and transmitted, based on the meta information, to one or more users on a social media network. | 10-10-2013 |
20130268523 | SYSTEM AND METHOD FOR DETERMINING USER OR RESOURCE INFLUENCE WITHIN A PRE-DEFINED CONTEXT - A method, system, apparatus, and computer program product provides the ability to determine the influence of a user or resource within a pre-defined context. A pre-defined context of activities is provided/defined. Point values are assigned to all activities that may occur within the pre-defined context. All activities for a single user or resource within the pre-defined context are tracked over a period of time. A score value for each activity for the single user or resource within the pre-defined context over a period of time is determined. A raw score is calculated for the single user or resource according to the total of all determined score values. The raw score value is normalized against scores of a population of other users or resources within the pre-determined context to provide a comparative scoring for users or resources. | 10-10-2013 |
20130268543 | SYSTEM AND METHOD FOR RECOMMENDING CONTENT - A method, system, apparatus, and computer program product provide the ability to recommend content to a particular user. Two content recommendation techniques are implemented and generated different content recommendation scores that are relative to a particular piece of content and the particular user. The two scores are reconciled to generate an overall content recommendation score for the particular piece of content and the particular user. | 10-10-2013 |
20140025688 | DETERMINING, DISTINGUISHING AND VISUALIZING USERS' ENGAGEMENT WITH RESOURCES ON A SOCIAL NETWORK - A method, apparatus, system, and computer program product for displaying top fan status information relating to selected content in a social network. An item of content is selected in a social network application. An engagement score is determined for each of one or more first users. Each engagement score is based on interactions of each of the one or more first users with the selected item of content. A subset of the one or more first users that has interacted with the item of social content the most is identified and displayed. | 01-23-2014 |
20140089819 | HOVER CARD - A method, apparatus, system, and computer program product display information about selected content in a social network. Multiple icons representative of content are displayed. Via input from a user, an item of the content is selected by selecting one of the multiple icons. In response to the selecting, a tooltip is displayed. The tooltip includes relevant information about the selected item and affinity data that provides a probability of similar interests between the user and the selected item. | 03-27-2014 |
20140108386 | METHOD AND SYSTEM FOR PROVIDING AN AFFINITY BETWEEN ENTITIES ON A SOCIAL NETWORK - A method, apparatus, system, and computer program product provide an affinity between a first entity and a second entity on a social network. First affinity data for a first entity is determined. The first affinity data is first behavioral data and first categorical data. Second affinity data for the second entity is determined. The second affinity data is second behavioral data and second categorical data. The first affinity data is compared to the second affinity data resulting in an affinity score. The affinity score identifies a probability of similar interests between the first entity and the second entity based on behavioral similarities between the first behavioral data and the second behavioral data, and categorical similarities between the first categorical data and the second categorical data. The affinity score is then provided to the first entity. | 04-17-2014 |
Patent application number | Description | Published |
20110048659 | PROCESS OF MAKING A WET FORMED CELLULOSIC PRODUCT AND A WET FORMED CELLULOSIC PRODUCT - According to the disclosure, a process of making a wet formed cellulosic product and a wet formed cellulosic product are disclosed. The process includes providing a slurry, forming the slurry into a cellulosic product, dewatering the cellulosic product, drying the cellulosic product, and applying an additive to one or more of the slurry and the cellulosic product. The additive modifies one or more of bulk, charge, potential, cumulative pore volume, surface tension of the cellulosic product. | 03-03-2011 |
20110048661 | CELLULOSIC PRODUCT FORMING PROCESS AND WET FORMED CELLULOSIC PRODUCT - According to the disclosure, a wet form cellulosic product forming process and a wet formed cellulosic product are disclosed. The process includes providing a slurry, forming the slurry into a cellulosic product, dewatering the cellulosic product, and drying the cellulosic product. Further dewatering of the cellulosic product occurs through a non-mechanical mechanism. | 03-03-2011 |
20140231037 | CELLULOSIC PRODUCT FORMING PROCESS AND WET FORMED CELLULOSIC PRODUCT - According to the disclosure, a wet form cellulosic product forming process and a wet formed cellulosic product are disclosed. The process includes providing a slurry, forming the slurry into a cellulosic product, dewatering the cellulosic product, and drying the cellulosic product. Further dewatering of the cellulosic product occurs through a non-mechanical mechanism. | 08-21-2014 |
20150197889 | CELLULOSIC PRODUCT FORMING PROCESS AND WET FORMED CELLULOSIC PRODUCT - According to the disclosure, a wet form cellulosic product forming process and a wet formed cellulosic product are disclosed. The process includes providing a slurry, forming the slurry into a cellulosic product, dewatering the cellulosic product, and drying the cellulosic product. Further dewatering of the cellulosic product occurs through a non-mechanical mechanism. | 07-16-2015 |
Patent application number | Description | Published |
20100087758 | LAMINATED ULTRASONIC WAVEGUIDES FABRICATED FROM SHEET STOCK - A laminated ultrasonic waveguide and a method of fabrication thereof which comprises stamping at least two pieces of sheet stock to form stamped parts of the laminated ultrasonic waveguide. The stamped parts are then laminated together to form a laminated ultrasonic waveguide for transferring ultrasonic acoustic energy along a longitudinal axis of the laminated ultrasonic waveguide. In several disclosed embodiments, the laminated ultrasonic waveguide is part of an ultrasonic surgical instrument having an active tip end-effector which is placed in contact with tissue of a patient to couple ultrasonic energy transferred along the laminated ultrasonic waveguide to the tissue. The stamped pieces of sheet stock can also be stamped to form one or more channels extending along the length of the laminated ultrasonic waveguide. The laminated ultrasonic waveguide can also define a connector at a proximal end thereof to transfer ultrasonic energy into the laminated ultrasonic waveguide. In different embodiments, the laminated ultrasonic waveguide comprises first and second (and third or more) stamped pieces of sheet stock which are laminated together. | 04-08-2010 |
20100262172 | ULTRASONIC SURGICAL BLADE HAVING TRANSVERSE AND LONGITUDINAL VIBRATION - An ultrasonic surgical blade includes an ultrasonic-surgical-blade body having a longitudinal axis, a distal tip, a proximal end adapted for longitudinal ultrasonic vibrational excitation, a most-distal longitudinal vibration node, a treatment portion extending from the distal tip toward the most-distal longitudinal vibration node, and a functional asymmetry. The functional asymmetry is asymmetric about the longitudinal axis and translates longitudinal ultrasonic vibrational movement of the proximal end into a combination of a longitudinal ultrasonic vibration and a transverse ultrasonic vibration in at least some of the treatment portion of the ultrasonic-surgical-blade body. An amplitude of the transverse ultrasonic vibration at the distal tip is less than substantially ten percent of a maximum amplitude of the transverse ultrasonic vibration of the treatment portion of the ultrasonic-surgical-blade body. An alternate embodiment of the ultrasonic surgical blade includes at least one functional asymmetry and at least one balance asymmetry. | 10-14-2010 |
20100262173 | BALANCED ULTRASONIC END EFFECTOR - A balanced ultrasonic surgical instrument according to the present invention includes an ultrasonic transmission rod which is connected to a blade or end effector by a balance portion, which includes first and second balance asymmetries designed to compensate for the imbalances induced by the blade. | 10-14-2010 |
20110319918 | BALANCED ULTRASONIC END EFFECTOR - A balanced ultrasonic surgical instrument according to the present invention includes an ultrasonic transmission rod which is connected to a blade or end effector by a balance portion, which includes first and second balance asymmetries designed to compensate for the imbalances induced by the blade. | 12-29-2011 |
Patent application number | Description | Published |
20090264909 | Ultrasonic shears stop pad - An ultrasonic-surgical-shears stop pad has a stop-pad body including a base material and at least one filler material. An alternate ultrasonic-surgical-shears stop pad has a stop-pad body adjacent to tissue pad. An ultrasonic surgical shears includes an ultrasonic surgical blade and a clamping arm which is operable to open and close toward the blade and which has a transversely and resiliently flexible distal tip. An alternate ultrasonic surgical shears includes an ultrasonic surgical blade, a clamping arm operable to open and close toward the blade, and a stop pad attached to the clamping arm and having a blade contact surface, wherein at least a portion of the stop pad is resiliently flexible in a direction substantially perpendicular to the blade contact surface. | 10-22-2009 |
20090270891 | Balanced ultrasonic curved blade - Methods and devices that provide reduced transverse motion in a curved ultrasonic blade and/or ultrasonic surgical instrument with functional asymmetries. An ultrasonic blade in accordance with embodiments of the present invention includes a curved functional portion of an ultrasonic blade, wherein the center of mass of the curved functional portion lies on the mid-line of a waveguide delivering ultrasonic energy to the blade. Balancing in accordance with embodiments of the present invention, using placement of the center of mass of the curved portion of the blade appropriately, provides blade balance in a proximal portion of the blade, without reduction of mass and inherent stress increase proximal to the end-effector. | 10-29-2009 |
20100063525 | Ultrasonic shears force limiting - The present invention relates to an improved arrangement for limiting the force applied to tissue by a mounted pivotal clamp arm of the present clamp coagulator apparatus and providing the appropriate amount of force to correctly positioned tissue. The arrangement is desirably economical in configuration, and cooperates with the associated pivotal clamp arm to position and maintain the clamp arm in substantial alignment with an associated end-effector, notwithstanding normal manufacturing tolerances of the components. | 03-11-2010 |
20100063526 | Jaw - The present invention relates generally to ultrasonic surgical devices, and more particularly to an ultrasonic surgical clamp coagulator apparatus for coagulating and/or cutting tissue, including an arrangement for pivotally mounting a clamp arm of the apparatus in order to form an improved jaw useful in manipulating tissue. | 03-11-2010 |
20100063527 | Tissue pad - The present invention relates generally to ultrasonic surgical devices, and more particularly to an ultrasonic surgical clamp coagulator apparatus for coagulating and/or cutting tissue, including an improved tissue pad for securing tissue within a clamp arm of a surgical clamp coagulator. | 03-11-2010 |
20100063528 | Ultrasonic shears actuating mechanism - The present invention is directed to an improved arrangement for mounting the pivotal clamp arm of the present clamp coagulator apparatus and providing the means to slideably engage the clamp arm via an outer actuating tube sliding over a non-actuating inner tube upon which the clamp arm is mounted. The arrangement is desirably economical in configuration, and cooperates with the associated pivotal clamp arm to position and maintain the clamp arm in substantial alignment with an associated end-effector, notwithstanding normal manufacturing tolerances of the components. | 03-11-2010 |
Patent application number | Description | Published |
20090083435 | ONLINE PLAYBACK SYSTEM WITH COMMUNITY BIAS - A method for entertaining individuals according to a community having similar tastes. Information derived from user accounts form the basis of a community and collateral preferences allow other subscribing individuals to enjoy the benefit of wider-ranging tastes according to the preferences expressed by the other members of the community. Additionally, assuming that individuals sharing one preference in common may be likely to share others, the present method allows those who choose to listen to the “fan station” the ability to enjoy similar music or other data streams according to preferences expressed by the fan community as a whole. | 03-26-2009 |
20090089327 | SYSTEM AND METHOD FOR SOCIAL PROGRAMMING OF MEDIA SOURCES - A method, system and user interface are provided for building and programming an online media (radio or TV) station based on collaboration by the station's users. The method includes creating an initial playlist for an online media station; creating a set of recommended media content items distinct from the initial playlist; aggregating user input regarding the recommended media content items; and generating a new playlist in accordance with the aggregated input. The user input regarding a given item of media content may include a positive vote or a negative vote. Each item added to the playlist after the initial playlist is voted on by the users, so that each item of the new playlist has an aggregated positive vote greater than a predetermined vote threshold. | 04-02-2009 |
20090177654 | SYSTEM AND METHOD FOR LEVERAGING MEDIA VIA USER RATING DATA - A method and system for leveraging user media file rating data. In one aspect, the system comprises a component in communication with a plurality of media file related services, a rating storage, and a component for making the user rating data available to be used by plural services so that each respective service can use the rating data to tailor a user experience during interaction by the particular user with the respective service. In one aspect, the user preference rating is received from any of the media file related services. In one aspect the user preference rating information and the associated media file information are associated with a particular user regardless of the respective media file related service the preference rating was received from. | 07-09-2009 |
20130132409 | Systems And Methods For Providing Multiple Media Items To A Consumer Via A Simplified Consumer Interaction - Methods and systems of providing media to a media consumer are disclosed herein. A media rating for at least one media item can be received from a consumer and stored on a consumer profile. Using a consumer interaction, the media consumer can request to import all available media having a consumer rating higher than a predetermined threshold to an online media library of the consumer. In another embodiment, using a consumer interaction, the media consumer can request to add to an online music library all media items associated with an artist, a genre, or other media item attribute. | 05-23-2013 |
Patent application number | Description | Published |
20100125585 | Conjoint Analysis with Bilinear Regression Models for Segmented Predictive Content Ranking - Information with respect to users, items, and interactions between the users and items is collected. Each user is associated with a set of user features. Each item is associated with a set of item features. An expected score function is defined for each user-item pair, which represents an expected score a user assigns an item. An objective represents the difference between the expected score and the actual score a user assigns an item. The expected score function and the objective function share at least one common variable. The objective function is minimized to find best fit for some of the at least one common variable. Subsequently, the expected score function is used to calculate expected scores for individual users or clusters of users with respect to a set of items that have not received actual scores from the users. The set of items are ranked based on their expected scores. | 05-20-2010 |
20120084155 | PRESENTATION OF CONTENT BASED ON UTILITY - Methods and systems for presenting content such as articles based on utility are provided. In one embodiment, a plurality of articles are determined, each article in the plurality of articles including article content and a corresponding preview icon, the preview icon defining a link to the corresponding article content when presented. For each article in the plurality of articles, a user experience utility value is determined. And for each article in the plurality of articles, an economic utility value is also determined. A ranked order of the articles is determined based upon each article's user experience utility value and economic utility value. And a portion of the preview icons of the articles are presented on a graphical display page in a priority orientation based on the ranked order of the articles. | 04-05-2012 |
20150310018 | Social Media Based Content Selection System - A method for selecting a social media network user. The method comprises obtaining one or more parameters indicative of quality of social media network content from the social media network user, ranking the social media network user based on the one or more parameters, and determining whether the social media network user is selected based on the ranking. | 10-29-2015 |
Patent application number | Description | Published |
20090094095 | RECOMMENDATIONS BASED ON AN ADOPTION CURVE - Methods and apparatus, including computer program products, for recommendations based on adoption curve. A method includes tracking over a period of time user popularity of a media content using a web service residing in a server, the popularity and period of time representing a life cycle of each of the media content. The method tracks over the period of time users enrolled in the web service and when in the period of time each of the users adopted the tracked media content and associates adopted media content with user profiles representing the users. The method recommends media content associated with a first user who adopted the tracked media content earlier in the period of time to a second user who may want to adopt the tracked media content subsequently in the period of time. | 04-09-2009 |
20100205166 | INTERNET RADIO AND BROADCAST METHOD - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be audio, video, or other works, such as popular music or the like, or other works, including music videos. Using a large database on the order of tens or hundreds of thousands of songs, users may indicate their general or specific preferences with regards to song, artists, or albums. Other users, particularly ones who access the system often, can act as influencers or controllers of the music transmitted to the user. Any other aspects or factors that might affect the user's preferences can be taken into account, such as popular radio stations in the United States or anywhere in the world. A playlist is created that combines all of these factors, as well as any applicable statutory regulations. The playlist then serves as the basis for feeding the data streams to the user, who is then able to enjoy music generally of his or her choosing, while additionally being exposed to new music (if the user so prefers). An Internet radio is thus established using the expansive and diverse abilities present in the Internet. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. Every individual then is like the manager of his or her own radio station and may broadcast to him- or herself the music that parallels his or her tastes. Other users may also choose to hear the same playlist as another individual, or allow that individual to influence their playlist. | 08-12-2010 |
20130103535 | RECOMMENDATIONS BASED ON AN ADOPTION CURVE - Methods and apparatus, including computer program products, for recommendations based on adoption curve. A method includes tracking over a period of time user popularity of a media content using a web service residing in a server, the popularity and period of time representing a life cycle of each of the media content. The method tracks over the period of time users enrolled in the web service and when in the period of time each of the users adopted the tracked media content and associates adopted media content with user profiles representing the users. The method recommends media content associated with a first user who adopted the tracked media content earlier in the period of time to a second user who may want to adopt the tracked media content subsequently in the period of time. | 04-25-2013 |
20140181152 | INTERNET RADIO AND BROADCAST METHOD - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 06-26-2014 |
20150106320 | INTERNET RADIO AND BROADCAST METHOD PERSONALIZED BY RATINGS FEEDBACK - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106321 | INTERNET RADIO AND BROADCAST METHOD PERSONALIZED BY GENRE - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106404 | INTERNET RADIO AND BROADCAST METHOD WITH SELECTABLE EXPLICIT LYRICS FILTERING - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106441 | INTERNET RADIO AND BROADCAST METHOD WITH ARTIST PORTAL - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106451 | INTERNET RADIO AND BROADCAST METHOD PERSONALIZED BY DJ - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106718 | INTERNET RADIO AND BROADCAST METHOD PERSONALIZED BY SOCIAL CURATION - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150106727 | INTERNET RADIO AND BROADCAST METHOD WITH DISCOVERY SETTINGS - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-16-2015 |
20150112830 | INTERNET RADIO AND BROADCAST METHOD WITH MUSIC PURCHASING - Data streams are generally selected according to user preferences and transmitted to the user in general alignment with expressed preferences of the user. Such data streams may be music, including music videos. Users may indicate their general or specific preferences with regards to song, artists, or albums. Any other aspects or factors that might affect the user's preferences can be taken into account. A playlist is created that combines all of these factors. The playlist then serves as the basis for feeding the data streams to the user. Each user is able to express his or her own preferences and receive music corresponding to those preferences on an on-going basis. | 04-23-2015 |