Patent application number | Description | Published |
20120248111 | Container Cap with Kink-Resistant Connector - A cap for use in a neck of a laboratory vessel, such as a roller bottle, is disclosed. In embodiments, the cap is assembled from two parts, an annular skirted cap body and a cap insert. In embodiments the cap insert has integral connectors for attaching tubing, vents, filters, or the like. In embodiments, the cap insert fits into the annular skirted cap body through a rotatable fitting. In embodiments, when the cap is assembled, the top portion of the cap, having integral connectors, is rotatably fitted to the annular side wall of the cap. | 10-04-2012 |
20120295343 | CLOSURE ASSEMBLY FOR CELL CULTURE APPARATUS - A closure assembly for a cell culture apparatus includes a port and a snap cap. The port has an annular sidewall defining an opening in communication with a cell culture chamber of a cell culture apparatus. The sidewall has (i) external threads for cooperating with internal threads of a twist cap and (ii) an annularly protruding snap cap engagement feature. The snap cap has a top and an annular sidewall extending from the top. The sidewall of the snap cap has an inwardly annularly projecting element configured to engage with the annularly protruding snap cap engagement feature of the port such that, when fully engaged, the snap cap is not readily removed from the port by unaided human force. | 11-22-2012 |
Patent application number | Description | Published |
20130037596 | DEVICE FOR APPLYING ADJUNCT IN ENDOSCOPIC PROCEDURE - A modular end effector delivers a therapeutic agent onto tissue that has been severed and/or stapled. The end effector is removably attached to a device. The device applies force to a piston of the end effector. The force causes a distal movement of a piston along a wall disposed within the end effector. The piston engages with agents stored on opposite sides of the wall, moving the agents distally to a mixture space. The agents are mixed in the mixture space and expelled through a tip. Staples may be embedded in or disposed below a foam block, which is disposed within a staple cartridge. Via an endoscopic stapling device, coated staples are driven through tissue while interacting with another agent on the device or the cartridge. The interaction forms a tissue restoring material that is applied onto the tissue. | 02-14-2013 |
20130041406 | SURGICAL STAPLE WITH LOCALIZED ADJUNCT COATING - A medical fastener has a first, pre-deployment shape for loading into a surgical instrument, and a second, post-deployment shape for connecting tissue together, and includes a crown and a pair of legs, each leg substantially transversely extending from a respective end of the crown in the first, pre-deployment shape. A coating, such as a hemostatic agent, is applied to a fastener interior surface defined by interior surfaces of the crown and the pair of legs. | 02-14-2013 |
20130075447 | ADJUNCT THERAPY DEVICE FOR APPLYING HEMOSTATIC AGENT - A surgical instrument includes a handle portion, a shaft housing a firing bar, an end effector comprising an anvil, a lower jaw, and a stapling and severing assembly responsive to a longitudinal closing motion produced by the handle portion and the shaft. The lower jaw is configured to receive a removable cartridge. The cartridge includes a housing, a plurality of staples disposed in the housing, and a deck disposed over the plurality of staples. The deck defines apertures, with each aperture being substantially disposed over each staple. The cartridge further receives a buttress material stored in one or both of the anvil or cartridge. The material is releasable onto severed tissue via a firing bar severing the buttress material in response to the longitudinal closing motion. | 03-28-2013 |
Patent application number | Description | Published |
20120117054 | Query Analysis in a Database - A method of analyzing an expression to infer output data properties, comprises storing, in a storage device, a root node “e” in R, in which “e” is an expression and R is a root node of an abstract syntax tree (AST) of the expression “e”, storing a number of child nodes of R into C | 05-10-2012 |
20120290590 | CONSTRUCTING A PROJECTION FOR STORING DATA - A method for constructing a projection for storing data on a storage device may include causing a processor to extract characteristics of expected output of a query on the data, and to construct a projection for the data based on the extracted characteristics. | 11-15-2012 |
20120290615 | SWITCHING ALGORITHMS DURING A RUN TIME COMPUTATION - A system and method for switching algorithms during a run time computation, the method including configuring hardware of a networked cluster of processing elements, each processing element with a memory hierarchy, to perform a first-tier algorithm on input data, the input data having cardinality and stored on one or a plurality of nodes in the networked cluster. Performing at least a portion of a second-tier algorithm and determining whether to complete the second-tier algorithm and perform a third or subsequent tier algorithm, the determination dependent on cardinality. Automatically passing data to an output if the cardinality of the second-tier algorithm is greater than a threshold cardinality, and passing the data back to the second-tier algorithm or to one or a plurality of subsequent algorithms, in response to the cardinality being less than the threshold, and automatically passing the data to an output at the completion of the data processing. | 11-15-2012 |
20130290287 | EXECUTING USER-DEFINED FUNCTION ON A PLURALITY OF DATABASE TUPLES - A method for executing a user-defined function on a plurality of input database tuples. The method may include causing a processor to invoke the function once; and to compute results of the function for the plurality of database tuples. | 10-31-2013 |
20130290294 | EVALUATION BY NESTED QUERIES - A system, method, and non-transitory computer readable medium are disclosed herein to optimize nested queries. At least one field is associated with each row of data evaluated by at least one nested query. A value is assigned to the at least one field so as to indicate whether each row of data satisfies the at least one nested query. The at least one field associated with each row of data is evaluated to determine satisfaction of the at least one nested query. | 10-31-2013 |
20140324889 | EXECUTING USER-DEFINED FUNCTION ON A PLURALITY OF DATABASE TUPLES - According to an example, in a method for executing a user-defined function on a plurality of database tuples, the user-defined function and an analysis function may be obtained. In addition, the plurality of database tuples may be divided into parts by a processor, the processor may be caused to execute the analysis function on each of the parts, and the processor may be caused to execute the user-defined function on at least one of the parts for which the analysis function returned a true predicate. | 10-30-2014 |
20150052107 | OBJECT DEPENDENCY MANAGEMENT - A method for object dependency management for historical access includes assigning versions to states of a structure for storing objects, and assigning the versions to dependency changes between the objects. The method further includes managing historical access to the objects based on an analysis of the versions and the dependency changes between the objects. | 02-19-2015 |
20150088865 | QUERY PROCESSING - A method for query processing includes receiving a query, and determining a query type by determining if the query is a structured query language (SQL) query including multiple distinct aggregates (MDAs), or a SQL query including cube, rollup or grouping sets operations. Based on the determination, the method includes processing the query to generate an output, and performing a predetermined number of maximum group by operations on the output based on the query type to generate a response to the query. | 03-26-2015 |
20150178342 | USER-DEFINED LOADING OF DATA ONTO A DATABASE - As part of managing the loading of data from a source onto a database, according to an example, an interface through which a user is to define logic related to the loading of the data onto the database is provided. The user-defined logic pertains to at least one of a user-defined location identification of the source, a user-defined filter to be applied on the data, and a user-defined parsing operation to be performed on the data to convert the data into an appropriate format for the database. In addition, the user-defined logic is received and the user-defined logic is implemented to load the data onto the database. | 06-25-2015 |
Patent application number | Description | Published |
20130339500 | Simulation of Network Conditions for Video Delivery - In one embodiment, a method receives a request for a video stream of video content from a client. A playlist for the video stream is retrieved. The playlist is for a plurality of portions of video content. A traffic shaping service adjusts the playlist for a set of portions in the plurality of portions according to a set of rules where adjusting allows the service to perform traffic shaping for the set of portions. The method then sends the adjusted playlist to the client. During playback of the video content at the client, the traffic shaping service receives a request for a portion in the set of portions from the client using the adjusted playlist. The method determines a rule to apply to the portion where the rule is associated with a network condition and simulates the network condition for the portion to perform the traffic shaping service. | 12-19-2013 |
20130340022 | Architecture for Simulation of Network Conditions for Video Delivery - In one embodiment, a method includes retrieving a playlist for a video stream of video content for a client. The playlist is for portions of video content for the video stream. A traffic shaping service determines a set of rules for the playlist for a set of portions in the plurality of portions where each rule is associated with a network condition. For each rule, the method performs: dynamically allocating a port and setting a network condition to apply to the port according to the rule. During playback of the video content, the traffic shaping service receives a request for a portion from the client and determines a port associated with the request for the portion. The method then sends a traffic shaped portion through the determined port where the network condition is applied to the traffic shaped portion based on the network condition being set on the port. | 12-19-2013 |
20140156805 | Remote Automated Updates for an Application - In one embodiment, a method updates a media program streaming application for a media program streaming service. The method downloads the application, which includes a bootstrap application, through a distribution site. The bootstrap application receives a manifest from a remote server that lists remote core files. The bootstrap application determines if a core memory contains updateable core files corresponding to the remote core files. The method determines if an updateable core file is present in the core memory that matches a remote core file and loads the updateable core file from the core memory into a memory. If an updateable core file that matches the remote core file is not present in the core memory, the method requests the remote core file from the remote server and loading the received remote core file into the memory. The method then executes the core files in the memory without recompilation. | 06-05-2014 |
20140181877 | Device Activation Using Encoded Representation - In one embodiment, a method activates a first device for delivering media to the first device. The method captures, by a second device, an encoded representation being output by the first device. The encoded representation is output by an application upon being provided on the first device where activation of the first device via a server is necessary for configuring a media program delivery service for a user on the first device. The method then determines information encoded in the encoded representation. The information includes a unique identifier (ID) for the first device. A user identifier is determined for the user and the method automatically communicates the unique ID and the user identifier to the server associated with the media program delivery service to allow the server to activate the first device for the media delivery service using the unique ID. | 06-26-2014 |
20150237394 | Device Activation for a Service Using an Outputted Representation - In one embodiment, a method activates a first device for using a service. A second device receives, from a third device, a user identifier for a user and a unique identifier for the first device. The user identifier originates from the third device and the unique identifier originates from the first device in a representation outputted by the first device. The second device determines a user account for the service, the user account being associated with the user identifier for the user. The second device associates the unique identifier for the first device with the user account. Then, the second device communicates with the first device to activate the first device to use the service in response to receiving the user identifier and the unique identifier. The second device allows access to the service from an application running on the first device. | 08-20-2015 |
Patent application number | Description | Published |
20130022238 | Systems and methods for tracking and authenticating goods - Systems and methods for identifying, tracking, tracing and determining the authenticity of a good include an imaging system, a database, and an authentication center. The imaging system is configured to capture an image of a unique signature associated with a good. The unique signature can be, for example, a random structure or pattern unique to the particular good. The imaging system is configured to process the image to identify at least one metric that distinguishes the unique signature from unique signatures of other goods. The database is configured to receive information related to the good and its unique signature from the imaging system, and to store the information therein. The authentication center is configured to analyze the field image with respect to the information stored in the database to determine whether the unique signature in the field image is a match to the captured image stored in the database. | 01-24-2013 |
20130195326 | MEDICATION STORAGE DEVICE AND METHOD - Devices, systems, and methods for monitoring and enhancing patient adherence to a prescription drug regimen are disclosed herein. In some embodiments, a medication storage device includes a plurality of dose containers, each dose container having an interior region configured to contain a medication. The medication storage device also includes an event detection system that includes a plurality of sensors. The plurality of sensors are configured to detect a change in each dose container of the plurality of dose containers. The medication storage device also includes an imaging system. The imaging system includes a plurality of image capture devices configured to capture an image of the interior region of each dose container of the plurality of dose containers. A communications module is configured to send an indication of the change detected by the event detection system and/or an image captured by the imaging device to a remote device. | 08-01-2013 |
20130284803 | Systems and Methods for tracking and authenticating goods - Systems and methods for identifying, tracking, tracing and determining the authenticity of a good are described herein. In some embodiments, a system includes an imaging system, a database, and an authentication center. The imaging system is configured to capture an image of a unique signature associated with a good at the good's origin. The unique signature can be, for example, a random structure or pattern unique to the particular good. The imaging system is configured to process the image of the good to identify at least one metric that distinguishes the unique signature from unique signatures of other goods. The database is configured to receive information related to the good and its unique signature from the imaging system; and is configured to store the information therein. The authentication center is configured to analyze the field image with respect to the information stored in the database to determine whether the unique signature in the field image is a match to the captured image stored in the database. | 10-31-2013 |
20140149131 | METHODS AND SYSTEMS FOR DRUG DIVERSION TRACKING - Methods and systems of patient compliance monitoring. Patient compliance monitoring includes receiving, from a user, a specification of a patient and retrieving prescription data associated with the specification. Compliance monitoring further includes receiving one or more codes associated with a dispensed prescription and determining whether the patient is compliant with the prescription data as a function of the prescription data and the one or more codes. Compliance monitoring also includes communicating an indication of whether the patient is compliant to the user. | 05-29-2014 |
20150053755 | Systems and methods for tracking and authenticating goods - Systems and methods for identifying, tracking, tracing and determining the authenticity of a good are described herein. In some embodiments, a system includes an imaging system, a database, and an authentication center. The imaging system is configured to capture an image of a unique signature associated with a good at the good's origin. The unique signature can be, for example, a random structure or pattern unique to the particular good. The imaging system is configured to process the image of the good to identify at least one metric that distinguishes the unique signature from unique signatures of other goods. The database is configured to receive information related to the good and its unique signature from the imaging system, and is configured to store the information therein. The authentication center is configured to analyze the field image with respect to the information stored in the database to determine whether the unique signature in the field image is a match to the captured image stored in the database. | 02-26-2015 |
Patent application number | Description | Published |
20100168119 | COMPOSITIONS AND METHODS FOR MINIMIZING OR REDUCING AGONIST-INDUCED DESENSITIZATION - Methods and compositions are provided for preventing or reversing loss of the therapeutic effect of a drug, where the loss is associated with the repeated administration of the drug to a patient. The method includes administering to the patient a dopamine receptor agonist or partial agonist or a drug that increases the extracellular level of dopamine by enhancing release of dopamine, decreasing the removal of dopamine from the extracellular space, enhancing the synthesis of dopamine within the brain, or decreasing metabolic degradation of dopamine; and also administering to the patient an opioid receptor antagonist in an ultra-low dose amount, wherein the ultra-low dose amount is effective to prevent or reverse loss of therapeutic effects associated with the repeated administration of the drug to the patient. The methods are useful for various treatments, including treating Parkinson's Disease, Restless Leg Syndrome, depression, schizophrenia, psychostimulant drug abuse, or attention deficit disorder. | 07-01-2010 |
20130190343 | COMPOSITIONS AND METHODS FOR MINIMIZING OR REVERSING AGONIST-INDUCED DESENSITIZATION - Methods and compositions are provided for preventing or reversing loss of the therapeutic effect of a drug, where the loss is associated with the repeated administration of the drug to a patient. The method includes administering to the patient a dopamine receptor agonist or partial agonist or a drug that increases the extracellular level of dopamine by enhancing release of dopamine, decreasing the removal of dopamine from the extracellular space, enhancing the synthesis of dopamine within the brain, or decreasing metabolic degradation of dopamine; and also administering to the patient an opioid receptor antagonist in an ultra-low dose amount, wherein the ultra-low dose amount is effective to prevent or reverse loss of therapeutic effects associated with the repeated administration of the drug to the patient. The methods are useful for various treatments, including treating Parkinson's Disease, Restless Leg Syndrome, depression, schizophrenia, psychostimulant drug abuse, or attention deficit disorder. | 07-25-2013 |
20150080422 | COMPOSITIONS AND METHODS FOR MINIMIZING OR REVERSING AGONIST-INDUCED DESENSITIZATION - Methods and compositions are provided for preventing or reversing loss of the therapeutic effect of a drug, where the loss is associated with the repeated administration of the drug to a patient. The method includes administering to the patient a dopamine receptor agonist or partial agonist or a drug that increases the extracellular level of dopamine by enhancing release of dopamine, decreasing the removal of dopamine from the extracellular space, enhancing the synthesis of dopamine within the brain, or decreasing metabolic degradation of dopamine; and also administering to the patient an opioid receptor antagonist in an ultra-low dose amount, wherein the ultra-low dose amount is effective to prevent or reverse loss of therapeutic effects associated with the repeated administration of the drug to the patient. The methods are useful for various treatments, including treating Parkinson's Disease, Restless Leg Syndrome, depression, schizophrenia, psychostimulant drug abuse, or attention deficit disorder. | 03-19-2015 |
20150202199 | TREATMENTS FOR DEPRESSION AND OTHER DISEASES WITH A LOW DOSE AGENT - The present invention relates to improved compositions and methods for the treatment or prevention of various diseases, including forms of depression, including, for example, breakthrough depression and treatment-refractory depression, and other mood disorders, as well as Parkinson's disease, bipolar disorder, bipolar disorder, attention deficit disorder (ADHD), Restless Leg Syndrome (RLS), and obesity. In some embodiments, the compositions and methods comprise low dose naltrexone or related opioid antagonists. | 07-23-2015 |
20150342946 | Treatments For Depression And Other Diseases With A Low Dose Agent - The present invention relates to improved compositions and methods for the treatment or prevention of various diseases, including forms of depression, including, for example, breakthrough depression and treatment-refractory depression, and other mood disorders, as well Parkinson's disease, bipolar disorder, bipolar disorder, attention deficit disorder (ADHD), Restless Leg Syndrome (RLS), and obesity. In some embodiments, the compositions and methods comprise low dose naltrexone or related opioid antagonists. | 12-03-2015 |
Patent application number | Description | Published |
20090259327 | METHOD AND SYSTEM FOR UNIFIED AUDIO CONTROL ON A PERSONAL COMPUTER - A system and method for improved audio controls on a personal computer is provided. The system and method provide a unified architecture for audio controls across hardware and software interfaces of the personal computer. An intelligent facility may automatically change audio controls for users to simply interact with various communications and media applications. To this end, a configurable audio controller intelligently handles various aspects of the system's audio devices by following various rules that may be based at least in part on user-configurable settings and a current operating state. The present invention also provides audio controls so that a user may easily change audio settings such as the volume of an audio output device. There are many applications that may use the present invention for automatic control of audio devices based upon the user's context. | 10-15-2009 |
20090305695 | REAL-TIME COMMUNICATIONS ARCHITECTURE AND METHODS FOR USE WITH A PERSONAL COMPUTER SYSTEM - A system and method for improved real-time communications in a computer system that eliminates the distinctions between various communication devices, communication channels and types of communication, including voice, text and video, is provided. When connected for communication, the user may easily move between modalities, including switching devices on which the user is communicating, switching networks, and transitioning between types of communication. A computer system includes various integrated communications-related devices, and a controller controls those devices based on user actions entered via buttons or user interface software and provides notifications to the user. The user is able to input data via any appropriate input mechanism, and receive data on any suitable output mechanism. Improved non-linear caller ID navigation is also provided. | 12-10-2009 |
20100008488 | METHOD AND SYSTEM FOR UNIFIED AUDIO CONTROL ON A PERSONAL COMPUTER - A system and method for improved audio controls on a personal computer is provided. The system and method provide a unified architecture for audio controls across hardware and software interfaces of the personal computer. An intelligent facility may automatically change audio controls for users to simply interact with various communications and media applications. To this end, a configurable audio controller intelligently handles various aspects of the system's audio devices by following various rules that may be based at least in part on user-configurable settings and a current operating state. The present invention also provides audio controls so that a user may easily change audio settings such as the volume of an audio output device. There are many applications that may use the present invention for automatic control of audio devices based upon the user's context. | 01-14-2010 |
20100010653 | METHOD AND SYSTEM FOR UNIFIED AUDIO CONTROL ON A PERSONAL COMPUTER - A system and method for improved audio controls on a personal computer is provided. The system and method provide a unified architecture for audio controls across hardware and software interfaces of the personal computer. An intelligent facility may automatically change audio controls for users to simply interact with various communications and media applications. To this end, a configurable audio controller intelligently handles various aspects of the system's audio devices by following various rules that may be based at least in part on user-configurable settings and a current operating state. The present invention also provides audio controls so that a user may easily change audio settings such as the volume of an audio output device. There are many applications that may use the present invention for automatic control of audio devices based upon the user's context. | 01-14-2010 |
20120200518 | METHOD AND SYSTEM FOR UNIFIED AUDIO CONTROL ON A PERSONAL COMPUTER - A system and method for improved audio controls on a personal computer is provided. The system and method provide a unified architecture for audio controls across hardware and software interfaces of the personal computer. An intelligent facility may automatically change audio controls for users to simply interact with various communications and media applications. To this end, a configurable audio controller intelligently handles various aspects of the system's audio devices by following various rules that may be based at least in part on user-configurable settings and a current operating state. The present invention also provides audio controls so that a user may easily change audio settings such as the volume of an audio output device. There are many applications that may use the present invention for automatic control of audio devices based upon the user's context. | 08-09-2012 |
Patent application number | Description | Published |
20100312754 | METHOD AND SYSTEM FOR BACKUP AND RECOVERY - A method and system for backup and recovery of data objects accessible to a computer system may identify data events associated with the data objects. Metadata providing a record of data events associated with a data object, including information identifying prior versions of a data object may be stored in a central index. An indication of a plurality of data objects may be displayed on a single panel display object, along with a revision history for each displayed data object. The revision history may include an indication of previous versions of the data object, which may be selectable and accessible from the single panel display object. The single panel display object may further display a timeline with a selectable timescale. The timescale may be associated with a color scale, which may also be used in the display of the data objects and their respective revision histories. | 12-09-2010 |
20110055164 | METHOD AND SYSTEM FOR MAINTAINING DATA RECOVERABILITY - A method and system for maintaining data recoverability of a computer system coupled to a storage device storing data objects includes identifying at least one recoverability parameter associated with the storage device. A recoverability index is calculated based on a recoverability parameter. The recoverability index may reflect the recoverability of the computer system from data loss. The recoverability index may be continuously calculated and evaluated. Recoverability actions, such as performing a backup operation, may be performed in response to a value associated with the recoverability index. | 03-03-2011 |
20140002580 | PORTABLE PROPRIOCEPTIVE PERIPATETIC POLYLINEAR VIDEO PLAYER | 01-02-2014 |
20140002581 | PORTABLE PROPRIOCEPTIVE PERIPATETIC POLYLINEAR VIDEO PLAYER | 01-02-2014 |
20140002582 | PORTABLE PROPRIOCEPTIVE PERIPATETIC POLYLINEAR VIDEO PLAYER | 01-02-2014 |
Patent application number | Description | Published |
20130225671 | Methods of Treating Seizure Disorders - Seizure disorders are treated by Ras inhibitors. In an embodiment, the Ras inhibitor includes a farnesyl transferase inhibitor. In another embodiment, the farnesyl transferase inhibitor includes a 3-hydroxy-3-methylglutaryl-Coenzyme A reductase inhibitor. In another embodiment, the 3-hydroxy-3-methylglutaryl-Coenzyme A reductase inhibitor is not a Ras inhibitor. Subjects having fragile X syndrome, autism, Angelman syndrome, Costello syndrome, cardio facio cutaneous syndrome, neurofibromatosis type I, Noonan syndrome and Coffin-Lowry syndrome that have seizure disorders can be treated. | 08-29-2013 |
20130261186 | Methods of Treating Autism - Subjects having autism are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen. The humans can be administered the GABA(B) agonist in a single dose or multiple doses. | 10-03-2013 |
20150057315 | Methods for Treatment of 16P11.2 Microdeletion Syndrome - Subjects that have a 16p11.2 microdeletion syndrome are treated by administering compositions that include mGluR inhibitors, including mGluR antagonists that include mGluR negative allosteric modulators. Administration of compositions employed in the methods of the invention can treat psychiatric, including neuropsychiatric disorders, cognitive impairments, attention, obesity, intellectual disability and seizure disorders. | 02-26-2015 |
Patent application number | Description | Published |
20100029770 | Methods of treating mental retardation, down's syndrome, fragile X syndrome and autism - Subjects having at least one condition selected from the group consisting of mental retardation, Down's syndrome, fragile X syndrome and autism are treated with a composition that includes gamma-aminobutyric acid agonists and/or M1 muscarinic receptor antagonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen. GABA(B) agonists can be used in combination with Group I mGluR antagonists and M1 muscarinic receptor antagonists in methods of treating humans. | 02-04-2010 |
20120122986 | Methods of Treating Fragile X Syndrome - Subjects having fragile X syndrome are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen, including racemic and R-baclofen. | 05-17-2012 |
20120129940 | METHODS OF TREATING AUTISM - Subjects having autism are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen. | 05-24-2012 |
20120142785 | METHODS FOR TREATING ALZHEIMER'S DISEASE - Alzheimer's disease is treated with an amphetamine compound. In one embodiment, the method includes administering an l-amphetamine compound. In another embodiment, the method includes administering an l-methamphetamine compound. | 06-07-2012 |
20130012586 | Methods of Treating Fragile X Syndrome - Subjects having fragile X syndrome are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen, including racemic and R-baclofen. | 01-10-2013 |
20130012587 | Methods of Treating Autism - Subjects having autism are treated with a composition that includes gamma-aminobutyric acid agonists. The gamma-aminobutyric acid agonist (GABA) can be a GABA(B) agonist, such as baclofen. | 01-10-2013 |
Patent application number | Description | Published |
20090180879 | Flexible Impeller Apparatus and Method - Embodiments of the invention provide an impeller assembly having a flexible impeller and a method of replacing a removable drive mechanism. The impeller assembly includes an impeller having an outer portion defining a substantially cylindrical shape, at least one flexible blade extending radially outward from the outer portion, and a first bore extending a first axial length. The impeller assembly also includes a tubular insert supported at least partially within the first bore. The tubular insert has a second bore defining a substantially cylindrical shape with a first radial distance from an axis passing through the center of the impeller, and a key portion radially extending from the second bore. The key portion defines a second radial distance from the axis larger than the first radial distance. | 07-16-2009 |
20100296921 | Socket with Bearing Bore and Integrated Wear Plate - Embodiments of the invention provide a pump with a housing including a pump chamber and an impeller positioned within the pump chamber. The pump also includes a socket with a wear plate, an inner ring, and an outer ring. The wear plate at least partially defines the pump chamber. The impeller is in contact with the wear plate. An outer surface of the outer ring is coupled to the housing. An inner surface of the outer ring receives a bearing. The inner ring receives a seal. A portion of the housing is molded over an end of the socket. | 11-25-2010 |
20110030822 | Dry Run Porting System - Embodiments of the invention provide a pump including an inlet port, an outlet port, a pumping chamber, and a porting system. The porting system includes an inlet tube including a trap in which a first volume of fluid can be collected. The porting system includes a reservoir with a first chamber and a second chamber separated by a partial port wall. The second chamber receives fluid directed over the partial port wall from the pumping chamber. The reservoir collects a second volume of fluid substantially equal to the first volume of fluid. The first volume of fluid and second volume of fluid provide enough fluid trapped inside the pump to allow the pump to temporarily operate when substantially no fluid is flowing into the inlet port. | 02-10-2011 |
Patent application number | Description | Published |
20110067387 | Thermally Efficient Exhaust Treatment System for an Internal Combustion Engine - An exhaust system for an engine comprises a cylinder head having an integral exhaust manifold to collect exhaust gas exiting the engine combustion chambers. An exhaust gas conduit in fluid communication with the exhaust manifold comprises an inlet end connected to the cylinder head, a portion that extends towards an upper end of the internal combustion engine and an outlet end configured to define an inlet end of a multistage catalytic converter. The catalytic converter comprises a canister having an inlet end located adjacent the top of the engine and includes first and second catalyst substrates and a collector closing an outlet end of the canister. The outlet end of the canister is located adjacent to the bottom of the engine, and the first and the second catalyst substrates receive and convert constituents of exhaust gas passing from the inlet end of the canister to the outlet end. | 03-24-2011 |
20110174566 | Internal Combustion Engine and Vehicle Packaging for Same - A motor vehicle has an internal combustion engine mounted in a central tunnel of the vehicle floor pan. The internal combustion engine comprises an engine block assembly having a lower end closed by an oil pan and an upper end extending at an angle α from a rear of the engine block assembly to a front thereof. An engine block closes the upper end and defines a crankcase that is configured to house a crankshaft for rotation therein. A cylinder housing assembly is reclined from vertical, towards the rear of the engine block, about an axis of the crankshaft by an angle β. At least a portion of the cylinder housing assembly and the crankcase are disposed in the central tunnel of the vehicle floor pan. | 07-21-2011 |
20140338992 | POWERTRAIN AND STEERING ASSEMBLY LAYOUT - A vehicle includes an engine assembly configured to power a vehicle. The engine assembly defines a first engine end and a second engine end opposite the first engine end. The first engine end is spaced apart from the second engine end along a first direction. The engine assembly defines a third engine end and a fourth engine end opposite the third engine end. The third engine end is spaced apart from the fourth engine end along a second direction. The second direction is substantially perpendicular to the first direction. The vehicle further includes a steering assembly disposed in close proximity to the engine assembly. The steering assembly includes a steering body disposed closer to the first engine end than to the second engine end. | 11-20-2014 |
20150360551 | INTEGRATED POWERTRAIN AND CHASIS DESIGN FOR MAXIMIZED PASSENGER CABIN VOLUME OF A VEHICLE - A vehicle includes a vehicle structure that extends along a longitudinal axis. An engine includes a crankshaft that defines a crank axis disposed substantially transverse to the longitudinal axis. A transmission includes an output shaft that defines a transmission output axis substantially parallel with the crank axis. The transmission output axis is disposed nearer the forward end of the vehicle structure than the crank axis. The crank axis is disposed vertically above the transmission output axis a distance of about 140 mm. The engine includes at least one cylinder bore that defines a bore axis disposed perpendicular to and may intersect the crank axis. The bore axis may be angled toward the forward end of the vehicle structure to define an angle between the bore axis and a vertical plane. The angle between the bore axis and the vertical plane may be about 18°. | 12-17-2015 |