Barile, US
Christopher Jeffrey Barile, San Carlos, CA US
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20110301180 | Reducing Platelet Activation, Aggregation and Platelet-Stimulated Thrombosis or Blood Coagulation by Reducing Mitochondrial Respiration - It has been discovered that inhibiting mitochondrial respiration in platelets reduces platelet activation or platelet aggregation. Certain heterocyclic compounds significantly reduced one or more platelet functions including clumping, sticking or platelet-stimulated clotting. Thus diseases or disorders mediated by inappropriately high levels of platelet activation or platelet aggregation can be treated by administering a therapeutically effective amount of a heterocyclic compound or nonheterocyclic mitochondrial inhibitor that significantly reduces one or more platelet functions including clumping, sticking or platelet-stimulated clotting, preferably in a reversible manner. | 12-08-2011 |
Daniela Barile, Davis, CA US
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20130195803 | BOVINE MILK OLIGOSACCHARIDES - Oligosaccharides from bovine milk, whey and dairy products, and methods of producing bovine milk oligosaccharides are provided. | 08-01-2013 |
Dawn Barile, Highland Heights, OH US
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20150092906 | MULTIPLE IMAGING MODALITY IMAGING APPARATUS - An imaging apparatus includes a first imaging modality ( | 04-02-2015 |
Elisa Barile, San Diego, CA US
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20110212961 | Pyrazole Derivatives as Kinase Inhibitors - The present invention provides compounds having the general structure I, or a pharmaceutically acceptable salt thereof: | 09-01-2011 |
Elisa Barile, La Jolla, CA US
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20150051138 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES - Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed. | 02-19-2015 |
20150073054 | INHIBITORS OF FURIN AND OTHER PRO-PROTEIN CONVERTASES - Disclosed herein are Furin/PC inhibitors for inhibiting Furin and other Propprotein Convertases. Method of making the Furin/PC inhibitors, chemical and biological characterization of the Furin/PC inhibitors, and the use of the Furin/PC inhibitors to treat infectious diseases, cancers, and inflammatory/autoimmune disorders, are also disclosed. | 03-12-2015 |
Gaetano Barile, River Vale, NJ US
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20080207499 | Rage-related methods for treating and preventing diabetic retinopathy - This invention provides a method for treating diabetic retinopathy in a subject afflicted therewith, comprising administering to the subject's eyes a therapeutically effective amount of soluble RAGE or a derivative thereof, thereby treating diabetic retinopathy in the subject. This invention further provides a method for inhibiting the onset of diabetic retinopathy in a subject afflicted therewith, comprising administering a prophylactically effective amount of soluble RAGE or a derivative thereof to the subject's eyes, thereby inhibiting the onset of diabetic retinopathy in the subject. | 08-28-2008 |
Gaetano R. Barile, River Vale, NJ US
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20160139120 | RAGE AS A C1Q RECEPTOR, METHODS AND APPLICATIONS - A method of identifying a compound capable of reducing or increasing the amount of the receptor for RAGE-C1q Binding comprising a) providing an amount of the compound to be tested; b) contacting the amount of the compound with C1q and RAGE; c) measuring the amount of RAGE-C1q binding in step b); d) comparing the amount of RAGE-C1q binding measured in step c) with the amount of RAGE-C1q binding measured under corresponding conditions in the absence of the compound; and e) identifying the compound as capable of reducing or increasing the amount of RAGE-C1q binding. The present invention also provides a method of treating a subject suffering from a RAGE-related disorder comprising administering to the subject a therapeutically effective amount of a compound that is a modulator of the amount of RAGE-C1q binding so as to thereby treat the subject. | 05-19-2016 |
Gaetano R. Barile, Hawthorn, NJ US
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20090180950 | Polychromatic, diversely-sized particles for angiography - The invention involves polychromatic particles of various sizes for assessing blood flow, blood barrier leakage and blood vessel leakage. | 07-16-2009 |
Gaetano R. Barile US
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20160139120 | RAGE AS A C1Q RECEPTOR, METHODS AND APPLICATIONS - A method of identifying a compound capable of reducing or increasing the amount of the receptor for RAGE-C1q Binding comprising a) providing an amount of the compound to be tested; b) contacting the amount of the compound with C1q and RAGE; c) measuring the amount of RAGE-C1q binding in step b); d) comparing the amount of RAGE-C1q binding measured in step c) with the amount of RAGE-C1q binding measured under corresponding conditions in the absence of the compound; and e) identifying the compound as capable of reducing or increasing the amount of RAGE-C1q binding. The present invention also provides a method of treating a subject suffering from a RAGE-related disorder comprising administering to the subject a therapeutically effective amount of a compound that is a modulator of the amount of RAGE-C1q binding so as to thereby treat the subject. | 05-19-2016 |
Gennaro A. Barile, Secaucus, NJ US
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20110152954 | BROACH HANDLE WITH FLEXURE SPRING - An instrument for holding a surgical tool or bone implant includes a handle with a bearing surface formed in one end for engaging the surgical tool. An elastically deformable plate is mounted on the handle body the plate having a catch element formed on a leading end thereof adapted to engage a coupling element formed on the surgical tool. The elastically deformable plate includes a cam follower formed in a recess thereon and includes a deformable spring section intermediate the can elements and the plate end with the catch element. An elongated pivotable loading member is rotatably mounted on the handle body. The loading member includes a cam surface for engaging the cam follower surface on the deformable plate. The cam surface on the loading member is shaped to elastically deform the elastically deformable plate section in a direction away from the plate catch element to thereby load and maintain a connecting force between the plate and the surgical tool or bone implant. | 06-23-2011 |
20130331849 | GLENOSPHERE INSERTER AND IMPACTOR - An impactor for connection to a concave surface of an implant has a shaft extending along a first axis from a first end to a second end. The shaft first end includes a pivot surface surrounding an internal shaft bore. The internal bore extends along the first axis and is open at the first end and extends towards the second end about the first axis. The internal bore has a pin extending through the shaft and intersecting the bore. A resilient element is mounted in the shaft bore spaced towards the shaft second end. A post is mounted in the shaft bore along the first axis. The post has a first end engaging a threaded bore in the concave surface of the implant. The post has a second end engaging the resilient element and a slot therein slidably engaging the pin and a collar pivotally mounted on the shaft. | 12-12-2013 |
20140066994 | INSTRUMENT FOR USE IN BENDING SURGICAL DEVICES - A system for bending a surgical device is disclosed in which the system may include a bending apparatus having a housing with a series of posts received therein. In some embodiments, one of the series of posts may be selectively movable within an elongate slot in the housing, while another of the series of posts may be radially movable. Movement of the radially movable post may serve to bend a surgical device about at least one of the other remaining posts. A tool may also be provided with the system for interacting with a lever and causing the radially movable post to move radially. An alternate apparatus for bending a surgical device is also disclosed, as are methods of bending a surgical device using the aforementioned system. | 03-06-2014 |
20140180295 | PATIENT-SPECIFIC CUTTING GUIDE FOR THE SHOULDER - Disclosed herein are devices and methods for guiding a surgical instrument for resecting a portion of a humerus of a patient. The surgical instrument is a patient-specific cutting guide having a base portion having a contact surface shaped to substantially match an outer surface of a neck portion of the humerus. The guide includes at least one proximal stabilization member extending medially from the base portion and having a contact surface shaped to substantially match an outer surface of a head portion of the humerus. The guide further includes at least one distal stabilization member extending distally from the base portion and having a contact surface shaped to substantially match an outer surface of a shaft portion of the humerus. The base portion includes a guide slot for guiding the surgical instrument. | 06-26-2014 |
Ian Barile, Palo Alto, CA US
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20140009475 | ANIMATION IN THREADED CONVERSATIONS - A method for augmenting a threaded conversation between a first device and a second device. The method includes: receiving a selection of a selectable animation, via a selection of a selectable animation representation, at the first device, wherein the selectable animation is configured for augmenting the threaded conversation; and incorporating the selection of the selectable animation into the threaded conversation such that the selectable animation appears in a conversation view of the first device and the second device. | 01-09-2014 |
20140122327 | CROSS BORDER GIFT CARDS - International transactions from a first country to a second country can be facilitated using a gift card purchased by a purchaser in the first country from a seller entity, conveyance of a code or other redemption information to a recipient in the second country, and redemption of the code or other redemption information at a redeeming entity. Methods, systems, article of manufacture and the like are described. | 05-01-2014 |
20140233916 | INTEGRATING SELECTED VIDEO FRAMES INTO A SOCIAL FEED - A method for integrating selected video frames into a social feed is described. The method includes: accessing a video stream at a device; detecting a set of features within at least one frame of the video stream to achieve a detected set of features; determining at least one moment comprising a combination of the detected set of features to achieve a determined at least one moment; accessing an integration instruction associated with the determined at least one moment; and integrating a selected moment of the determined at least one moment into a social feed based on the integration instruction. | 08-21-2014 |
20150052206 | CREATING A CONTACT LIST AND PRE-POPULATED USER ACCOUNTS - Systems and methods are disclosed for creating a contact list and pre-populated user accounts. An existing contact list associated with a first user is imported at a computer system. A second contact list is created for the first user for a user account associated with a social network service wherein the second contact list comprises members from the existing contact list. Members of the existing contact list whom already have a user account with the social network service are filtered into a first category. Members of the existing contact list whom do not have a user account with the social network service are filtered into a second category. Pre-populated user accounts associated with the social network service are created for the members in the second category. | 02-19-2015 |
Ian Barile, Mountain View, CA US
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20100115614 | DATA LOSS PROTECTION THROUGH APPLICATION DATA ACCESS CLASSIFICATION - A method and apparatus for classifying behavior of an application based on its data access pattern is described. In one embodiment, the method includes monitoring file access events associated with an application, and determining whether at least one of the file access events indicates the application's attempt to manipulate data of a file. If at least one file access event indicates the application's attempt to manipulate the data within the file, then at least one action is caused to be performed. | 05-06-2010 |
20100162347 | ADAPTIVE DATA LOSS PREVENTION POLICIES - A monitor detects a policy violation on a computing device, wherein the policy violation includes a user attempt to perform an operation to move data that includes sensitive information off the computing device. The monitor determines whether one or more previous policy violations have occurred on the computing device. The monitor performs an action to minimize a risk of data loss based on the one or more previous policy violations. | 06-24-2010 |
20100306850 | BEHAVIORAL ENGINE FOR IDENTIFYING PATTERNS OF CONFIDENTIAL DATA USE - A client device hosts a behavioral engine. Using the behavioral engine, the client device analyzes behavior of a client application with respect to confidential information. The client device assigns a rating indicative of risk to the client application based on the behavior of the client application. The client device performs an action to mitigate risk of data loss if the rating exceeds a threshold. | 12-02-2010 |
Jason A. Barile, Indianapolis, IN US
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20140279405 | RESIDENTIAL REAL ESTATE APPRAISAL FORM ANALYSIS SYSTEMS AND RELATED METHODS - Embodiments of form analysis systems are disclosed herein. Other examples and related methods are also presented herein. | 09-18-2014 |
John Barile, Summit Point, WV US
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20130039837 | Method for the Continuous Recovery of Carbon Dioxide from Acidified Seawater - A method for recovering carbon dioxide from acidified seawater using a membrane contactor and passing seawater with a pH less than or equal to 6 over the outside of a hollow fiber membrane tube while applying vacuum or a hydrogen sweep gas to the inside of the hollow fiber membrane tube, wherein up to 92% of the re-equilibrated [CO | 02-14-2013 |
Maria A. Barile, Willowick, OH US
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20100275942 | COSMETIC NAIL COVERING - A cosmetic nail cover for cosmetically disguising, with a temporary covering and conventional nail polish, an unattractive nail area on a hand or foot digit, which includes an elongated strip of tape with adhesive and a pad. The material of the tape is resistant to damage by conventional nail polish chemicals, and is suitable for application and adherence of a coating of the conventional nail polish by conventional means. The adhesive substantially coats the back side of the strip of tape, and is suitable for removable adherence to skin of the hand or foot. The pad is flexible and has a firm smooth top surface for adherence to the back side of the strip of tape. Preferably the tape material is transparent and non-glossy, and the pad has thickness comparable to that of a nail and is trimmed to the size and shape appropriate for the nail area to be covered by it. | 11-04-2010 |
20120305019 | COSMETIC NAIL COVERING - Method and apparatus for cosmetically disguising an unattractive finger or toe nail area of a negatively affected hand or foot digit by using a temporary, cosmetically appealing covering, by providing a cosmetic nail covering that will simulate the appearance of a nearby normal nail when a suitably sized and shaped cosmetic nail covering is applied to cover the nail area of the affected digit, and both the cosmetic nail covering and the nearby normal nails of the hand or foot are coated by a user with identical user-supplied nail polish. The covering is made from adhesive tape suitable for wrapping around a digit, and a pad sized and shaped to resemble a normal nail for the affected digit when the pad is adhered to the tape. The tape should enable forming a coating that is as smooth, level, and uniformly colored as natural nails when coated by conventional polish. | 12-06-2012 |
Peter J. Barile, Palm Bay, FL US
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20080299643 | Systems and Methods for Large-Scale Production and Harvesting of Oil-Rich Algae - Systems and methods for the growing of microorganisms such as algae, yeast, and bacteria are described. Seed fermentation units are associated with final fermentation ponds in various arrangements. Continuous, semicontinuous, fed batch, and batch modes of operation of the seed and final fermentations are included. Harvest methods for the cellular material and related products are described. | 12-04-2008 |
Peter W. Barile, Morristown, TN US
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20110047845 | Device for Removably Mounting a Label on a Surroundable Surface - A device for removably mounting a label proximate a surroundable member such as a handle of a stackable chair. The device includes a body member having a first panel portion adapted to carry a label and an opposite second panel portion. Each of the first and second panel portions define inboard and outboard sides. A flexible portion is joined to and extends between the inboard sides of the panel portions. The flexible portion is adapted to flex around the surroundable member between a wrapped configuration and an unwrapped configuration. The second panel portion is releasably securable proximate the first panel portion in the wrapped configuration. | 03-03-2011 |
20120126588 | Ganging Cup-Holder - A ganging cup-holder | 05-24-2012 |
20150230615 | Flexible Back Chair with Spring Can Assembly - Disclosed is a chair containing a flexible back support frame mechanism that includes an improved spring assembly designed to allow reclining movement of a back support frame relative to a seat assembly. The spring can assembly of the present invention is, preferably, carried by a rear cross support member thereby eliminating the need for cumbersome elongated springs and their attendant support members. Further, the spring can assembly of the present invention allows the compression member to be readily and easily changed, thus providing the ability to easily adjust the flex tension of the back support member. | 08-20-2015 |
20150230616 | Flexible Back Chair with Improved Spring Can Assembly - Disclosed is a chair containing a flexible back support frame mechanism that includes an improved spring assembly designed to allow reclining movement of a back support frame relative to a seat assembly. The spring can assembly of the present invention is, preferably, carried by a rear cross support member thereby eliminating the need for cumbersome elongated springs and their attendant support members. Further, the spring can assembly of the present invention allows the compression member to be readily and easily changed, thus providing the ability to easily adjust the flex tension of the back support member. | 08-20-2015 |
Steven E. Barile, Portland, OR US
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20100057852 | Method of and apparatus for rating songs on internet radio and downloading related content - A method comprising: streaming songs through Internet radio to a portable device; connecting to the portable device through a network; obtaining feedback from a selected group of users of the portable device; providing a license to the songs to the users; and downloading the songs and related content to the portable device. | 03-04-2010 |
20100185662 | Method of and apparatus for playing, rating, and downloading songs from internet radio - A method comprising: playing songs on Internet radio; rating the songs; occasionally connecting to a network; gathering the songs that are higher rated; downloading the songs that are higher rated to a portable device; disconnecting the portable device from the network; and playing the songs that are higher rated on the portable device. | 07-22-2010 |
20110010429 | Method and apparatus for caching multimedia content from the internet on occasionally-connected devices - An arrangement is provided for caching multimedia content on occasionally connected devices. A play list is created and submitted to a multimedia content provider that provides and processes the desired multimedia content in the play list before the desired content is downloaded to a device. The device need only connect to the multimedia content provider for a period required to download the desired multimedia content. Once the desired multimedia content is in the device, the device can be carried with a user so that the user can access the multimedia content anywhere. | 01-13-2011 |