Patent application number | Description | Published |
20130209458 | FAB-GLYCOSYLATED ANTIBODIES - The present invention pertains to a method for controlling the circulation half-life of antibodies by adjusting the amount of sialic acid in the carbohydrates attached to the Fab part of the antibodies. Furthermore, the present invention provides antibodies having an increased circulation half-life. | 08-15-2013 |
20130273033 | HUMANIZED EGFR ANTIBODIES - The present invention pertains to humanized anti-EGFR antibodies having antigen binding properties similar to those of the murine or chimeric anti-EGFR antibody from which they are derived. In particular, the present invention is directed to humanized anti-EGFR antibodies which are useful in the treatment of cancer. | 10-17-2013 |
20150353959 | PEPTIDES FOR ENHANCING PROTEIN EXPRESSION - The present invention pertains to the field of recombinant protein production. Novel peptides derived from the extracellular region of a glycophorin protein are provided which enhance the expression rate of proteins or peptides of interest when expressed as fusion protein together with said novel peptides. | 12-10-2015 |
20150368363 | USE OF HUMAN CELLS OF MYELOID LEUKAEMIA ORIGIN FOR EXPRESSION OF ANTIBODIES - The invention relates to a method for producing a protein molecule composition having a defined glycosylation pattern, comprising (a) introducing in a host cell which is an immortalized human blood cell at least one nucleic acid encoding at least a part of said protein; and (b) culturing said host cell under conditions which permit the production of said protein molecule composition; and (c) isolating said protein molecule composition. | 12-24-2015 |
20160068609 | ANTI-CANCER TREATMENTS WITH ANTI-EGFR ANTIBODIES HAVING A LOW FUCOSYLATION - The present invention pertains to the field of cancer therapy using anti-cancer antibodies. The medical use of anti-EGFR antibodies having improved glycosylation characteristics, in particular a reduced fucosylation, is provided which show anti-cancer efficacy and an improved adverse side effect profile. | 03-10-2016 |
Patent application number | Description | Published |
20120068703 | METHOD FOR SPATIALLY RESOLVED DETERMINATION OF AN MR PARAMETER - In a magnetic resonance (MR) method and apparatus for spatially resolved determination of at least one MR parameter that influences an MR signal detected in an MR measurement of a region of an examination subject, first complex image data and second complex image data, respectively acquired with different acquisition coils and at different echo times in an echo imaging sequence, are provided to a processor. The different image data sets have complex image points that correspond with each other with regard to the imaged volume element of the examination subject. The MR parameter is determined in the processor for at least a portion of these image points by determination of an image point vector respectively for the first and second echo times and by combining the image point vectors to at least partially compensate echo time-independent phase or magnitude portions in the acquired image data. | 03-22-2012 |
20120092011 | MAGNETIC RESONANCE METHOD AND SYSTEM TO DETERMINE THE POSITION OF A SLICE RELATIVE TO A REGION MOVING RELATIVE TO THE SLICE - In a magnetic resonance method and system to determine a position of a slice relative to a region moving relative to the slice within a predetermined volume segment of an examination subject located in the magnetic resonance system, a physical property within the slice is detected with spatial resolution at multiple points in time, such that a time curve of the physical property is detected for at least one voxel of the slice. The position of the slice relative to the region is determined with respect to defined points in time, depending on the time curve. | 04-19-2012 |
20160069976 | METHOD AND APPARATUS FOR ACQUIRING MAGNETIC RESONANCE DATA FROM A TARGET REGION WHILE THE TARGET REGION MOVES DUE TO RESPIRATION - In a method for recording magnetic resonance data in a target region of a patient while the target region moves due to respiration a single-shot turbo spin echo sequence is used as a magnetic resonance sequence in a magnetic resonance apparatus. SPAIR fat saturation is used by emitting an inversion pulse at an inversion time before the data recording with the magnetic resonance apparatus. Multiple repetitions of the sequence of an inversion pulse, an inversion time and a data recording using the magnetic resonance sequence are triggered by a respiratory signal describing the respiratory cycle, each repetition occurring upon fulfillment of a recording criterion. At least one further inversion pulse is emitted in a waiting time between the sequences. | 03-10-2016 |
Patent application number | Description | Published |
20100248326 | STABILIZATION OF THERMOLYSIN IN AQUEOUS SOLUTION - The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form. | 09-30-2010 |
20110070622 | PURIFICATION OF COLLAGENASES FROM CLOSTRIDIUM HISTOLYTICUM LIQUID CULTURE - The present invention provides a method for purifying | 03-24-2011 |
20120244598 | Stabilization of Thermolysin in Aqueous Solution - The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form. | 09-27-2012 |
20150337282 | STABILIZATION OF THERMOLYSIN IN AQUEOUS SOLUTION - The present invention deals with the proteolytic enzyme thermolysin which tends to be unstable in aqueous solution. The invention provides methods and compositions to enhance the stability of dissolved thermolysin in aqueous solution. Thermolysin, crude thermolysin or a lyophilisate containing thermolysin and one or more salts, is contacted with an aqueous buffer with a low salt concentration and a first solution is formed. Subsequently, a further salt in solid form is added and dissociated, thereby forming a second solution comprising thermolysin in a stabilized form. | 11-26-2015 |
Patent application number | Description | Published |
20100013446 | METHOD FOR CONTROLLING THE SUPPLY VOLTAGE FOR AN INTEGRATED CIRCUIT AND AN APPARATUS WITH A VOLTAGE REGULATION MODULE AND AN INTEGRATED CIRCUIT - The present invention relates to a method for controlling the supply voltage for an integrated circuit, which is connected to a voltage regulation module via a sense line, a voltage supply line and a bus wherein the supply voltage is provided by the voltage regulation module ( | 01-21-2010 |
20120218031 | METHOD FOR CONTROLLING THE SUPPLY VOLTAGE FOR AN INTEGRATED CIRCUIT AND AN APPARATUS WITH A VOLTAGE REGULATION MODULE AND AN INTEGRATED CIRCUIT - The present invention relates to a method for controlling the supply voltage for an integrated circuit, which is connected to a voltage regulation module via a sense line, a voltage supply line and a bus wherein the supply voltage is provided by the voltage regulation module ( | 08-30-2012 |
20130113545 | METHOD FOR CONTROLLING THE SUPPLY VOLTAGE FOR AN INTEGRATED CIRCUIT AND AN APPARATUS WITH A VOLTAGE REGULATION MODULE AND AN INTEGRATED CIRCUIT - The present invention relates to a method for controlling the supply voltage for an integrated circuit, which is connected to a voltage regulation module via a sense line, a voltage supply line and a bus wherein the supply voltage is provided by the voltage regulation module ( | 05-09-2013 |
20130138978 | Charge Recycling Between Power Domains of Integrated Circuits - A mechanism is provided for efficiently recycling a charge from a power domain that is discharging. A side of a discharging power domain normally coupled to a voltage supply is disconnected from the voltage supply. The side of the precharging power domain normally coupled to the voltage supply is currently disconnected from the voltage supply. The side of the discharging power domain normally coupled to the voltage supply is connected to a side of the precharging power domain normally coupled to the voltage supply. A side of the discharging power domain normally coupled to the ground is disconnected from ground. The side of the discharging power domain normally coupled to ground is connected to the voltage supply, thereby precharging the precharging power domain with the charge from the discharging power domain that would normally he lost due to leakage. | 05-30-2013 |
20140082386 | Charge Recycling Between Power Domains of Integrated Circuits - A mechanism is provided for efficiently recycling a charge from a power domain that is discharging. A side of a discharging power domain normally coupled to a voltage supply is disconnected from the voltage supply. The side of the precharging power domain normally coupled to the voltage supply is currently disconnected from the voltage supply. The side of the discharging power domain normally coupled to the voltage supply is connected to a side of the precharging power domain normally coupled to the voltage supply. A side of the discharging power domain normally coupled to the ground is disconnected from ground. The side of the discharging power domain normally coupled to ground is connected to the voltage supply, thereby precharging the precharging power domain with the charge from the discharging power domain that would normally be lost due to leakage. | 03-20-2014 |
Patent application number | Description | Published |
20120006110 | SENSOR ARRANGEMENT FOR DETECTING AMBIENT CONDITIONS - The invention relates to a sensor arrangement for detecting ambient conditions, in particular for a motor vehicle, with at least one carrier plate and optical elements arranged on this carrier plate, wherein several of the optical elements are arranged around a shared central region on the carrier plate, and at least two of the optical elements arranged around the central region exhibit primary action axes. These primary action axes are adjusted at a predetermined angle relative to the carrier plate, wherein the primary action axes are directed toward the shared central region. Additional sensors arranged on the carrier plate include a rain sensor, a solar sensor as well as various light sensors, which preferably are arranged on receiving surfaces of the carrier plate. | 01-12-2012 |
20120006907 | SENSOR ARRANGEMENT FOR ACQUIRING STATE VARIABLES - The invention relates to a device for acquiring predetermined state variables inside a room, in particular in the interior of a motor vehicle, with at least one temperature sensor and with a humidity sensor, at least regions of which are enclosed by a housing, wherein a first temperature sensor exhibits at least one contact surface for abutting against a perimeter surface bordering the room, and that at least one second temperature sensor is provided inside the housing for acquiring the room temperature. The contact surface is thereby a surface piece of a printed circuit board section of a printed circuit board, which encompasses elastic characteristics, wherein the printed circuit board section encompasses a plurality of surface pieces, which are angled relative to one another, and the temperature sensors are arranged at different surface pieces. | 01-12-2012 |
20120007507 | METHOD AND SENSOR ARRANGEMENT FOR DETECTING THE VISIBILITY OUTSIDE OF A MOTOR VEHICLE - The invention relates to a method for detecting the visibility outside of a motor vehicle by means of at least two light sensors, in the case of which the intensity of the light reflection of the driving light emitted in the direction of travel is detected by means of a first light sensor, which is oriented in the direction of travel. The first light sensor thereby transmits at least a first evaluation signal to a control unit for further processing at least as a function of the recorded intensity of the light reflection. The ambient light is detected by means of a second light sensor and a second evaluation signal is transmitted to the control unit as a function of the intensity of the ambient light. The control unit correlates the evaluation signals of both light sensors and the light intensity threshold value is determined on the basis thereof. The control unit outputs different control signals in each case, in response the first evaluation signal is exceeding of falling below of the determined light intensity threshold value. | 01-12-2012 |
Patent application number | Description | Published |
20100224491 | Solid-State Electrolyte Gas-Sensor Element - A gas-sensor element having a layer-type arrangement or configuration, in particular for determining gas components and/or concentrations of gas components of a measuring gas, having a sensor cell, including a first electrode, which is to be exposed to the measuring gas, a second electrode, which is to be exposed to a reference gas, and a solid-state electrolyte situated between the two electrodes, including a reference-air channel situated between the electrode that is exposed to the reference gas and the solid-state electrolyte, and including a heating element. In the superposition of two gas-sensor element layers, a path formed by an electrode facing the heating element is developed at a lateral offset with respect to a path formed by the heating element. | 09-09-2010 |
20120111726 | Sensor Element Having Through-Hole Plating - A sensor element and a method of producing a sensor element is described. The sensor element being especially for identifying a physical property of a gas, especially for identifying the concentration of a gas component or the temperature of an exhaust gas of an internal combustion engine. The sensor element has a first solid electrolyte layer, the first solid electrolyte layer having a plated- through hole. The sensor element also has a conducting element which produces an electrically conducting connection from the upper side of the first solid electrolyte layer to the lower side of the first solid electrolyte layer through the plated-through hole. The first solid electrolyte layer in the plated-through hole is electrically insulated from the conducting element by an insulating element. The wall of the plated-through hole has a bevel. | 05-10-2012 |
Patent application number | Description | Published |
20110293374 | OIL-ABSORBENT POLYURETHANE SPONGES WITH GOOD MECHANICAL PROPERTIES - The present invention relates to a method for adsorbing and/or absorbing oil, by bringing oil into contact with a polyurethane sponge with excellent mechanical properties. | 12-01-2011 |
20120016066 | Biodegradable Material Composed Of A Polymer Comprising A Porous Metal-Organic Framework - The present invention relates to a biodegradable material in the form of a foil or a film, where the material comprises a polymer comprising at least one porous metal-organic framework and the at least one porous metal-organic framework comprises at least one at least bidentate organic compound coordinated to at least one metal ion. The invention further relates to food packaging comprising such a material and also its use for the packaging of foods and the use of a porous metal-organic framework for the absorption of ethene in food packaging. | 01-19-2012 |
20120058332 | BARRIER COATING MADE OF CYCLOOLEFIN COPOLYMERS - A barrier coating is described, where a polymer layer of thickness at least 1 μm is applied on a supportive substrate, selected from polymer foils, paper, and paperboard, and the polymer layer has been formed from a copolymer which can be produced via ring-opening metathesis polymerization of (a) olefin monomers, selected from monocyclic olefin monomers having 1 or 2 endocyclic C—C double bonds and bicyclic olefin monomers having an endocyclic C—C double bond, and (b) polycyclic olefin monomers having at least two C—C double bonds, e.g. a copolymer of cyclooctene and dicyclopentadiene. | 03-08-2012 |
Patent application number | Description | Published |
20110097411 | CARRIER PELLETS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF - The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body. | 04-28-2011 |
20140193509 | CARRIER PELLETS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF - The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body. | 07-10-2014 |
20150209286 | CARRIER PELLETS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF - The invention relates to a method for the production of carrier pellets for pharmaceutical active substances. Likewise, the invention relates to such carrier pellets and also to pharmaceutical formulations containing these. The carrier pellets according to the invention are used for transporting and releasing pharmaceutical active substances, in particular in the human body. | 07-30-2015 |
Patent application number | Description | Published |
20080210442 | Process for Preparing Low-Viscosity Polymer Gels - The invention relates to a process for preparing low-viscosity polymer gels by mixing a water-absorbing polymer with water, in which the viscosity is reduced by adding a chelating agent, and also to the use thereof for firefighting. | 09-04-2008 |
20080215026 | Superabsorbing Foam, Method for the Production and Use Thereof - A superabsorbent foam comprising from 0.01% by weight to 10% by weight of fibers composed of woodpulp or waste paper, based on the dry weight of the foam. | 09-04-2008 |
20090192036 | Method for the Production of Water Absorbent Polymer Particles by Polymerizing Drops of a Monomer Solution - The invention relates to a method for the production of water absorbent polymer particles by polymerizing drops, comprising at least one monomer in a gas phase surrounding the drops, wherein the drops are produced by surrounding a first monomer solution with a second monomer solution and polymerizing the second monomer solution to a higher cross-linked polymer than the first monomer solution. | 07-30-2009 |
20100268181 | Superabsorbent Foam with Graphics on the Surface - A superabsorbent foam which comprises at least 1% by weight, based on the total weight of the dry foam, of inorganic pulverulent solid and bears graphics on at least one of its surfaces is obtainable by a process in which a foamed monomer mixture which comprises an appropriate amount of inorganic solid is polymerized in a mold which bears graphics on at least one inner surface. | 10-21-2010 |
20110003685 | Polymeric Particles Capable of Absorbing Blood and/or Body Fluids - Polymeric particles capable of absorbing blood and/or body fluids, the polymeric particles being coated with at least one surfactant and with at least one solvent, are produced and used for absorbing blood and/or body fluids, especially in hygiene articles. | 01-06-2011 |
20110237724 | Process for Preparing Low-Viscosity Polymer Gels - The invention relates to a process for preparing low-viscosity polymer gels by mixing a water-absorbing polymer with water, in which the viscosity is reduced by adding a chelating agent, and also to the use thereof for firefighting. | 09-29-2011 |
20120295090 | Production of a Superabsorbent Foam of High Swell Rate - This invention relates to a process for producing superabsorbent foams comprising the steps of foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one blowing agent, at least one crosslinker and at least one surfactant, polymerizing the foamed mixture and drying the polymerized mixture, to the foams and also to their use for absorbing aqueous fluids. | 11-22-2012 |
20120296295 | FEMININE HYGIENE ABSORBENT ARTICLE COMPRISING A SUPERABSORBENT FOAM OF HIGH SWELL RATE - This invention relates to a feminine hygiene absorbent article comprising superabsorbent foams obtainable by foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one blowing agent, at least one crosslinker and at least one surfactant, polymerizing the foamed mixture and drying the polymerized mixture, to the foams and also to their use for absorbing aqueous fluids. | 11-22-2012 |
20120296296 | FEMININE HYGIENE ABSORBENT ARTICLES COMPRISING WATER-ABSORBING COMPOSITES - This invention relates to a feminine hygiene absorbent article comprising water-absorbing composites obtainable by foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 11-22-2012 |
20130316177 | METHOD FOR THE PRODUCTION OF ABSORBENT POLYMER PARTICLES BY POLYMERIZING DROPS OF A MONOMER SOLUTION - A process for preparing water-absorbing polymer beads by polymerizing droplets comprising at least one monomer in a gas phase surrounding the droplets, the droplets being obtained by enveloping a first monomer solution with a second monomer solution and polymerizing the second monomer solution and polymerizing to give a more highly crosslinked polymer than the first monomer solution. | 11-28-2013 |
20140158626 | WATER-ABSORBING COMPOSITES - This invention relates to a process for producing water-absorbing composites comprising the steps of foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 06-12-2014 |
20160000961 | FEMININE HYGIENE ABSORBENT ARTICLES COMPRISING WATER-ABSORBING COMPOSITES - This invention relates to a feminine hygiene absorbent article comprising water-absorbing composites obtainable by foaming an aqueous mixture comprising at least one monoethylenically unsaturated monomer bearing acid groups, at least one crosslinker, at least one initiator and at least one surfactant, contacting the foam obtained with at least one web of synthetic fibers and polymerizing, to the composites themselves and to their use for absorbing aqueous fluids. | 01-07-2016 |