Annett
Annett Boddrich, Falkensee DE
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20120282629 | Enhancers of Protein Degradation - The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof. | 11-08-2012 |
Annett Boeddrich, Falkensee DE
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20090117040 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases - The present invention relates to pharmaceutical and diagnostic compositions as well as to the use of the active substances contained therein for preparing a pharmaceutical or a diagnostic composition for the treatment or diagnosis of neurodegenerative disorders or amyloid diseases. | 05-07-2009 |
20130078186 | AZO COMPOUNDS REDUCING FORMATION AND TOXICITY OF AMYLOID BETA AGGREGATION INTERMEDIATES - The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates. | 03-28-2013 |
Annett Dorner-Reisel, Chemnitz DE
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20110127886 | PIEZOELECTRIC ACTUATOR AND METHOD FOR PRODUCING A PIEZOELECTRIC ACTUATOR - A fully active piezoelectric stack has alternately successive piezoelectric layers and inner electrodes which pass through to the outer side of the stack and each have a first region, which does not adhere or adheres poorly and a second region which adheres well to the coating. The inner electrodes are provided for the purpose of using their first regions to alternately contact-connect a first outer electrode and a second outer electrode. The outer side of the fully active piezoelectric stack is coated with the coating at least in regions which are assigned the outer electrodes. The coating is then removed in regions which border the first regions of the inner electrodes and the two outer electrodes are applied to the remaining coating, with the result that the outer electrodes contact-connect the first regions of the inner electrodes and the coating is otherwise arranged between the inner electrodes and the outer electrodes. | 06-02-2011 |
Annett Eylenstein, Gelnhausen DE
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20160068830 | METHOD FOR THE MANUFACTURING OF DI-CHAIN PROTEINS FOR USE IN HUMANS - This invention relates to a novel method for producing di-chain proteins for use in humans from single-chain precursors, including di-chain clostridial neurotoxins. The method comprises the step of expressing a nucleic acid sequence encoding a single-chain precursor comprising a thrombin-cleavage site and the step of cleaving the single-chain precursor with a human factor Xa or a human thrombin, particularly a human thrombin drug product authorized for human therapeutic use. The invention further relates to novel di-chain clostridial neurotoxins and nucleic acid sequences encoding such novel di-chain clostridial neurotoxins. | 03-10-2016 |
Annett Eylenstein, Gellnhausen DE
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20140377248 | METHOD FOR THE MANUFACTURING OF DI-CHAIN PROTEINS FOR USE IN HUMANS - This invention relates to a novel method for producing di-chain proteins for use in humans from single-chain precursors, including di-chain clostridial neurotoxins. The method comprises the step of expressing a nucleic acid sequence encoding a single-chain precursor comprising a thrombin-cleavage site and the step of cleaving the single-chain precursor with a human factor Xa or a human thrombin, particularly a human thrombin drug product authorized for human therapeutic use. The invention further relates to novel di-chain clostridial neurotoxins and nucleic acid sequences encoding such novel di-chain clostridial neurotoxins. | 12-25-2014 |
Annett Gersdorf, Hermsdorf DE
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20120234773 | ACIDIC SLUDGE ADSORPTION OF DNT WASTEWATERS - A process for working up alkaline process wastewater from the nitration of aromatic compounds to mono-, di- and trinitroaromatics, said alkaline process wastewater having a pH of 7.5 to 13, comprising the steps of | 09-20-2012 |
Annett Grott, Wolfertschwenden DE
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20120096809 | THERMOFORM PACKAGING MACHINE AND METHOD FOR STRETCHING A FILM WEB - The disclosure relates to a thermoform packaging machine for stretching a film web as well as to a method of operating a thermoform packaging machine, in the case of which a stretching station with a heating unit is provided, and the film web is actively cooled by means of a film cooling device after stretching of the film web. | 04-26-2012 |
Annett Hahn-Windgassen, Sunnyvale, CA US
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20130126356 | SIMULTANEOUS PURIFICATION OF CELL COMPONENTS - Methods and devices for purification of different cell components from the same sample are provided. | 05-23-2013 |
20130140182 | PROTEIN FRACTIONATION BASED ON pI - Methods and devices for detecting and collection analytes fractionated based on pI, separating analytes via electrophoresis and pI, and purifying a target molecule using pI focusing and subsequent crystallization are provided. | 06-06-2013 |
20130164860 | AFFINITY METHODS AND COMPOSITIONS EMPLOYING ELECTRONIC CONTROL OF PH - Methods and apparatuses for detection of target molecules are provided. | 06-27-2013 |
20130220830 | ELECTRONIC CONTROL OF PH AND IONIC STRENGTH - Apparatuses and methods for controlling ionic strength and/or pH of a solution are provided. | 08-29-2013 |
20140360878 | AFFINITY METHODS AND COMPOSITIONS EMPLOYING ELECTRONIC CONTROL OF PH - Methods and devices for purifying, detecting, and collecting analytes fractionated based on pI, separating analytes via electrophoresis and pI, and purifying a target molecule using pI focusing and subsequent crystallization are provided. | 12-11-2014 |
Annett Halbhuber, Scheinfeld DE
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20120015576 | Antimicrobially Treated and/or Stain-Repellant Planar Substrates and Method for Producing the Same - The invention relates to a planar or shaped textile material comprising or constituted of fibers, at least part of the fibers being coated with a hydrolytically condensed inorganic/organic hybrid material having single-walled or multi-walled carbon nanotubes which are embedded therein, optionally covalently bound thereto. The carbon nanotubes are preferably functionalized, especially with carboxylic acid groups or sulfanilic acid groups. The textile material is suitable for producing protective clothing, barrier materials or the like. The invention further relates to the use of the above-defined hybrid material as a coating material which imparts stain-resistance and/or antimicrobial properties to the coated substrate. | 01-19-2012 |
20120108707 | Wood Material Product and Method for the Production Thereof - The invention relates to a wood material product and a method for producing wood material products from particles containing lignocellulose and adhesives containing formaldehydes, which are intermixed and fed to a forming process after mixing. A zeolite is added to the mixture of adhesives and particles containing lignocellulose. | 05-03-2012 |
20140256859 | WOOD MATERIAL PRODUCT AND METHOD FOR THE PRODUCTION THEREOF - The invention relates to a wood material product and a method for producing wood material products from particles containing lignocellulose and adhesives containing formaldehydes, which are intermixed and fed to a forming process after mixing. A zeolite is added to the mixture of adhesives and particles containing lignocellulose. | 09-11-2014 |
Annett Kaeding-Koppers, Bad Fallingbostel DE
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20160067950 | Packaging Film and Packaging Process - A packaging film having a gas barrier layer and a sealing layer, is constructed such that the gas barrier layer has at least three sublayers with two outer sublayers composed of a polyamide (PA) and a middle sublayer which is arranged between the outer sublayers and is composed of ethylene-vinyl alcohol copolymer (EVOH), which sublayers are coextruded, and wherein the gas barrier layer is monoaxially stretched. Foodstuffs or other products can be packaged and sterilized within the packaging film by putting the product in the film and sealing the packaging by heating or exerting pressure on at least part of the film, and then heating at at least 100C for at least 10 minutes. | 03-10-2016 |
Annett Kutzschbach, Dresden DE
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20120240619 | METHOD AND DEVICE FOR TREATING A CARBON-DIOXIDE-CONTAINING GAS FLOW, WHEREIN THE ENERGY OF THE VENT GAS (WORK AND COLD DUE TO EXPANSION) IS USED - The invention relates to a method and a device for treating a carbon-dioxide-containing gas stream, in particular from a large-scale fired plant, e.g. from a power plant. The precompressed gas stream is separated in a carbon dioxide purification stage into a gas substream having an elevated carbon dioxide content (carbon dioxide product stream) and a gas substream having a decreased carbon dioxide content (vent gas stream). The carbon dioxide product stream is fed to further utilization and/or storage. In particular, by injecting the carbon dioxide underground, the emission of gases harmful to the climate can be reduced. For improving the energy efficiency, it is proposed that the vent gas stream is expanded in at least one expansion turbine and both the resultant kinetic energy and the resultant refrigeration are utilized for energy recovery. For utilizing the kinetic energy, the expansion turbine can be coupled to a compressor (booster) which compresses the crude gas stream and/or the carbon dioxide product stream. For utilizing the refrigeration generated in the expansion, the at least partially expanded vent gas stream can be brought into heat exchange with process streams which are to be cooled, e.g. the crude gas stream and/or the carbon dioxide product stream. | 09-27-2012 |
20130205829 | PROCESS AND DEVICE FOR TREATING FLUE GASES - A process and a device for treating a carbon dioxide-containing flue gas stream are described. At least a part of the carbon dioxide present is removed from the flue gas stream by means of a scrubber, forming a low carbon dioxide gas stream and a high carbon dioxide gas stream. The high carbon dioxide and water-saturated gas stream formed from the flue gas stream after removal of the carbon dioxide is cooled by means of a refrigeration system | 08-15-2013 |
Annett Linemann, Saarbrucken DE
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20110135860 | BLENDS OF TRANSPARENT AMORPHOUS POLYAMIDES BASED ON DIAMINES AND ON TETRADECANEDIOIC ACID AND SEMICRYSTALLINE POLYAMIDES - The present invention relates to a transparent amorphous polyamide which results from the condensation of at least one diamine chosen from aromatic, arylaliphatic and cycloaliphatic diamines, of tetradecanedioic acid or of a mixture comprising at least 50 mol % of tetradecanedioic acid and at least one diacid chosen from aliphatic, aromatic and cycloaliphatic dicarboxylic acids. The invention also relates to a composition comprising, by weight, 1 to 100% of the preceding polyamide and 99 to 0% of a semicrystalline polyamide. The invention also relates to the objects composed of the composition of the invention, such as panels, films, sheets, pipes, profiles or objects obtained by injection moulding. The invention also relates to objects covered with a transparent protective layer composed of the composition of the invention. | 06-09-2011 |
20150076886 | METHOD FOR PRODUCING A BACKREST REAR PANEL - In a method for producing a backrest rear panel from at least one organic sheet, a plurality of reinforcing beads and a frame-shaped bead, which circles the reinforcing beads, are formed in at least one organic sheet. In a molding tool, a rib structure is formed in the circling frame-shaped bead on the rear of the backrest rear panel in such a manner that a rib structure closes flush with the rear of the backrest rear panel, with the result that an even surface is formed on the rear of the backrest rear panel. A bonded connection is formed between the organic sheet and rib structure with the result that a one-piece component is formed. | 03-19-2015 |
Annett Lossack, Dusseldorf DE
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20100069285 | ACIDIC COMPOSITION BASED ON SURFACTANT BLEND - The present invention refers to a concentrate for use in a cleaning and/or washing process comprising | 03-18-2010 |
Annett Mikolasch, Griefswald DE
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20090280179 | Resorbable Calcium Phosphate Based Biopolymer-Cross-Linked Bone Replacement Material - A resorbable bone replacement material made of calcium phosphate particles of different phases which are embedded in an inventive-specific cross-linked collagen matrix. The goal is to form a non-brittle, bone replacement moulded body having a positive fit, i.e. having a shape which is anatomic and/or corresponds to the defect, which perfectly fills the bone defect and can be resorbed thereby. Said goal is achieved by producing the bone replacement material made of a mixture of calcium phosphate particles which is embedded in an inventive cross-linked collagen matrix. In particular, the collagen cross-linking is achieved by a Laccase-induced peptide cross-linking and suitable bridge molecules. Essentially substituted dihydroxyarmotes and/or substrates of the lignolytic polyphenoloxidases, such as Laccases, are suitable as bridge molecules. Also, monocyclic ortho-dihydroxyaromates, monocyclic para-dihydroxyaromates, bicyclic monohydroxyaromates, polycyclic monohydroxyaromates, bicyclic dihydroxyaromates, polycyclic dihydroxyaromates, bicyclic trihydroxyaromates, polycyclic trihydroxyaromates, or mixtures thereof are used. The inventive hydroxyaromates are not part of a polymer chain as opposed to the known conchal adhesive. | 11-12-2009 |
Annett Mikolasch, Greifswald DE
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20090318584 | Adhesive for Medical Applications and Means for Haemostasis - The invention relates to a kit comprising the following individual components: (a) polymers comprising at least one free amino group, (b) bridge molecules selected from the group consisting of monocyclic ortho-dihydroxyaromates, mono-cyclic para-dihydroxyaromates, bicyclic monohydrxyaromates, polycyclic monohydroxyaromates, bicyclic dihydroxyaromates, polycyclic dihydroxyaromates, bicyclic trihydroxyaromates, polycyclic trihydroxyaromates, and mixtures thereof, and (c) polyphenoloxidases, in particular, lignolytic polyphenoloxidases, whereby the individual components b) and c) are not in contact. | 12-24-2009 |
20110040086 | Novel Beta-Lactam Antibiotics, Methods for Their Production, and Their Use - The invention relates to novel antimicrobial agents that are based on β-lactam derivatives and are produced by reacting previously known β-lactam derivatives with polyphenol oxidase substrates under the influence of free radicals and by forming salts of any β-lactam derivatives with polyhexamethylene biguanide hydrogen carbonate. Said novel compounds are suitable as an antibiotic. | 02-17-2011 |
20110150943 | ADHESIVE FOR MEDICAL APPLICATIONS AND MEANS FOR HAEMOSTASIS - The invention relates to adhesives for medical applications and methods of their preparation and use. | 06-23-2011 |
Annett Müller, Mainz DE
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20130029986 | 3-(INDOLYL)- OR 3-(AZAINDOLYL)- 4-ARYLMALEIMIDE DERIVATIVES FOR USE IN THE TREATMENT OF COLON AND GASTRIC ADENOCARZINOMA - The present invention relates to the use of a compound of formula (I) wherein R | 01-31-2013 |
Annett Müller, Mainz DE
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20130029986 | 3-(INDOLYL)- OR 3-(AZAINDOLYL)- 4-ARYLMALEIMIDE DERIVATIVES FOR USE IN THE TREATMENT OF COLON AND GASTRIC ADENOCARZINOMA - The present invention relates to the use of a compound of formula (I) wherein R | 01-31-2013 |
Annett Notzel, Mulheim An Der Ruhr DE
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20150158125 | METHOD FOR PRODUCING A WELDED JOINT AND CREATING AN IMAGE OF THE WELDED JOINT BY MEANS OF COOLED X-RAY TUBES - A method for producing a welded joint is provided, including: providing an x-ray tube arranged within an x-ray housing for generating x-ray radiation and a detector arranged within a detector housing for receiving the x-ray radiation; flowing a cooling medium through the housing; heating components to be welded to the pre-heating temperature required for producing the welded joint; welding the welded joint; creating an exposure of the welded joint via the x-ray tubes and the detector at a temperature of the components which is essentially the pre-heating temperature or higher, wherein the cooling medium flows through the housing such that the x-ray tubes and the detector operate at the respective operating temperatures thereof. | 06-11-2015 |
Annett Ortscheid, Falkensee DE
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20140316498 | Releasable Contact Connection Arrangement for Electrodes on an Electromedical Device - A releasable contact connection arrangement for electrodes on an electromedical device, in particular for electrodes of active implants, such as neurostimulator devices, includes a contact end, which is provided on the electrode and comprises at least one electrical contact, a device-side connector head on the electromedical device, a connector opening on the connector head for anchoring the contact end of the electrode so as to produce an electrical contact connection and releasable mechanical fixing, and an anti-kink device at the exit of the contact end from the connector opening, wherein the anti-kink device includes a flexible anti-kink sleeve sitting on the contact end of the electrode before the at least one electrical contact, said anti-kink sleeve being slid via its fixing end facing the connector head into a receiving recess that is enlarged compared to the connector opening and being fastened therein. | 10-23-2014 |
Annett Overheu, Remseck DE
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20110148108 | COUPLING UNIT - A coupling unit having at least one tubular section; a casing; at least one detent ring, which is arranged radially between the casing and the at least one tubular section when the at least one tubular section, is inserted in the casing, wherein the at least one detent ring, the casing, and the at least one tubular section are configured to adapt to one another such that the tubular section is inserted axially into the casing in a first relative rotational position of the tubular section and the casing, wherein the tubular section is secured by the detent ring against axial withdrawal, the casing and tubular section can be rotated relative to one another, and wherein for decoupling purposes, the tubular section can be withdrawn axially from the casing in a second relative rotational position of the casing and the tubular section that differs from the first rotational position. | 06-23-2011 |
20120038153 | COUPLING UNIT - A coupling unit having at least one tubular section; a casing; at least one detent ring, which is arranged radially between the casing and the at least one tubular section when the at least one tubular section, is inserted in the casing, wherein the at least one detent ring, the casing, and the at least one tubular section are configured to adapt to one another such that the tubular section is inserted axially into the casing in a first relative rotational position of the tubular section and the casing, wherein the tubular section is secured by the detent ring against axial withdrawal, the casing and tubular section can be rotated relative to one another, and wherein for decoupling purposes, the tubular section can be withdrawn axially from the casing in a second relative rotational position of the casing and the tubular section that differs from the first rotational position. | 02-16-2012 |
Annett Richter, Berlin DE
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20140179745 | TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB - The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders. | 06-26-2014 |
20140241986 | FORMULATIONS OF FLUORINATED STILBENE SUITABLE FOR PET IMAGING - The invention is directed to formulations of lipophilic Amyloid beta ligand stilbene and more particularly to formulations which are capable to be administered parenterally e.g. intravenously, wherein the lipophilic Amyloid beta ligand stilbene is a fluorinated stilbene. Further, the invention is directed to a method for sterile filtration of formulations suitable for PET imaging of mammals pursuant to the invention. | 08-28-2014 |
20140296301 | TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAGENIB - The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders. | 10-02-2014 |
20150141448 | Topical Ophthalmological Pharmaceutical Composition containing Pazopanib - The present invention relates to topical ophthalmological pharmaceutical compositions containing pazopanib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders. | 05-21-2015 |
20150174096 | TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING SUNITINIB - The present invention relates to topical ophthalmological pharmaceutical compositions containing sunitinib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof and its process of preparation and its use for treating ophthalmological disorders. | 06-25-2015 |
20150328145 | TOPICAL OPHTHALMOLOGICAL PHARMACEUTICAL COMPOSITION CONTAINING REGORAFENIB - The present invention relates to topical ophthalmological pharmaceutical compositions containing regorafenib, a hydrate, solvate or pharmaceutically acceptable salt thereof or a polymorph thereof but without hydrophobic silica and its process of preparation and its use for treating ophthalmological disorders. | 11-19-2015 |
Annett Schneider, Rossdorf DE
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20130008898 | STAINLESS-STEEL DRUM CONTAINER - In a stainless-steel drum container ( | 01-10-2013 |