Alexander, MD
Keith B. Alexander, Fulton, MD US
Patent application number | Description | Published |
---|---|---|
20160112443 | CYBERSECURITY SYSTEM - A cybersecurity system for processing events to produce scores, alerts, and mitigation actions. The system includes sensors for receiving and processing data to form events, distributed analytic platform for processing events to form analytic workflows, and scoring engines for processing events using analytic workflows to produce scoring engine messages. The system also includes real time analytic engine for processing scoring engine messages and distributed analytic platform messages using the analytic workflows and analytic workflow and event processing rules to form and transmit a threat intelligence message. Threat intelligence messages include broadcast messages, mitigation messages, and model update messages. The system also includes logical segments which associate an analytic model, a set of analytic models, or an analytic workflow; one or more sources of inputs about activity within the logical segment, and a set of actions for mitigating an impact of the anomalous activity occurring within the logical segment. | 04-21-2016 |
Peter Alexander, Woodbine, MD US
Patent application number | Description | Published |
---|---|---|
20110119487 | System and method for encryption rekeying - Disclosed is a system and method for maintaining a secure, encrypted networking session across a communications network by dynamically replacing encryption keys during the networking session and without terminating the session. A secure control channel is embedded within the general encrypted network connection and is used to transport encrypted control messages from one network endpoint to another. In order to hide that fact that such control messages are being transferred (as opposed to general network data traffic), the control message data packets are formatted in a way to simulate the standard general network data packets. | 05-19-2011 |
Richard B. Alexander, Ellicott City, MD US
Patent application number | Description | Published |
---|---|---|
20080219972 | Prostatic Acid Phosphatase (Pap) Materials and Methods of Use Thereof in the Prophylactic and Therapeutic Treatment of Prostate Cancer - A nucleic acid molecule comprising at least one nucleotide sequence encoding SEQ ID NO: 14, 15, 19, 41, or a sequence that is at least about 95% identical thereto; a composition comprising same and a method of administering same to induce an immune response; a polypeptide consisting of SEQ ID NO: 14, 15, 19, 41, or a sequence that is at least about 95% identical thereto; a composition comprising same and a method of administering same to induce an immune response; a composition comprising APC, which have been exposed to the polypeptide, and a method of administering same to treat prostate cancer; a composition comprising T-cells, which are specific for an epitope in a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41 and a method of administering same to treat prostate cancer; a composition comprising an anti-idiotypic antibody having an internal image of an epitope of a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41 and a method of administering same to treat prostate cancer; and an immortal B-cell line that produces an anti-idiotypic monoclonal antibody having an internal image of an epitope of a polypeptide consisting of SEQ ID NO: 14, 15, 19, or 41. | 09-11-2008 |
20080260760 | Prostate-Specific Antigen-Derived Mhc Class H-Restricted Peptides and Their Use in Vaccines to Treat or Prevent Prostate Cancer - The present invention relates to immunogenic peptides derived from human prostate cancer antigen (PSA-derived peptides) and their use as vaccines to treat or prevent prostate cancer. The invention is also related to dendritic cells from a patient having prostate cancer, which dendritic cells have been exposed to one or more PSA-derived peptides, and their use to treat or prevent prostate cancer in the patient. The invention is also directed to T-cells from a patient which cells are specific for PSA-activated peptide(s), and their uses to treat or prevent prostate cancer. | 10-23-2008 |
Robert M. Alexander, Mount Airy, MD US
Patent application number | Description | Published |
---|---|---|
20110259666 | SOUND ATTENUATION CANOPY - A sound attenuation canopy for reducing levels of sound passing through an opening comprises a sound absorbing member. The sound absorbing member is comprised of a flexible sound absorbing material and has a first end, a second end and an intermediate portion extending between the first end and the second end. The first end is configured to attach to a periphery of the opening at a first location, the second end is configured to attach to a periphery of the opening at a second location and the intermediate portion is configured to be spaced apart from the opening. When the first end and the second end of the sound absorbing member are attached to the periphery of the opening, at least one side opening is at least partially defined by the intermediate portion and the perimeter of the opening, and a sound transmission flow path through open space between the opening and the side opening comprises at least one change of direction greater than 45 degrees. | 10-27-2011 |
20120103721 | SOUND ATTENUATION CANOPY - A sound attenuation canopy for reducing levels of sound passing through an opening comprises a sound absorbing member. The member is comprised of a flexible sound absorbing material and has a first end, a second end and an intermediate portion extending therebetween. The first end is configured to attach to the opening's periphery at a first location, the second end is configured to attach to the periphery at a second location and the intermediate portion is configured to be spaced apart from the opening. When the first end and the second end are attached to the periphery of the opening, at least one side opening is at least partially defined by the intermediate portion and the perimeter of the opening, and a sound transmission flow path through open space between the opening and the side opening comprises at least one change of direction greater than 45 degrees. | 05-03-2012 |
Roger Alexander, Rockville, MD US
Patent application number | Description | Published |
---|---|---|
20080285505 | SYSTEM AND METHOD FOR NETWORK TIMING RECOVERY IN COMMUNICATIONS NETWORKS - A system and method for determining the network timing of a communications network from a mobile station that receives signals from a plurality of base stations. An estimated location of a mobile station may be determined through any number of or combination of location technologies. Network measurements such as observed time difference values and/or a round trip time values at the mobile station or base stations in the network may be utilized. Network timing relationships may be determined as a function of the estimated location and network measurements. An estimated location of a second mobile station may be determined as a function of the network timing relationships. | 11-20-2008 |
20080287139 | SYSTEM AND METHOD FOR ESTIMATING THE LOCATION OF A MOBILE STATION IN COMMUNICATIONS NETWORKS - A system and method for estimating the location of a mobile station that receives signals from a plurality of base stations. An estimated location of a mobile station may be determined through any number of or combination of location technologies. Network measurements such as observed time difference values and/or a round trip time values at the mobile station or base stations in the network may be utilized. Network timing relationships may be determined as a function of the estimated location and network measurements. An estimated location of a second mobile station may be determined as a function of the network timing relationships. | 11-20-2008 |
20140269278 | INFORMATIONAL BROADCAST MESSAGES AND ITS USES IN WIRELESS MULTIHOP NETWORKS - In a wireless multihop network having node devices within communication range neighboring node devices in a corresponding local neighborhood, the node devices generate visibility messages to be transmitted via connection-less broadcast. The visibility messages include at least an identifier of the corresponding node device. Visibility messages received by each of the node devices from the one or more neighboring node devices are processed to determine a measure of density of the local neighborhood. This measure of density also accounts for the heterogeneous transmit power capabilities of node devices and is used for updating of one or more operational parameter of the node device relating to utilization of the radio communications medium by that node device. A degree of utilization of the medium through the control of transmission data rate and power is adjusted based on an inverse relation to the measure of density determined from the received visibility messages. | 09-18-2014 |
20140269704 | CONTROLLED FLOODING MECHANISM TO FACILITATE MESSAGE BROADCAST IN WIRELESS MULTIHOP NETWORKS - In a wireless multihop network having node devices within communication range neighboring node devices in a corresponding local neighborhood, the node devices initiate repeated message broadcasts of a first message as a connection-less broadcast into the local neighborhood. Initiation of message broadcasts is governed such that the message broadcasts are permitted only at specified transmission times within a plurality of transmission time windows. Each of the node devices determines whether any of the connection-less-broadcasted messages are duplicates of the first message, and generate a count of those duplicates received during each of the transmission windows. Based on counts of the duplicates, initiation of a message broadcast of the first message in a current transmission window is suppressed in response to a corresponding count of duplicates of the first message received during the first transmission window exceeding a suppression limit. | 09-18-2014 |
Roger Alexander, Germantown, MD US
Patent application number | Description | Published |
---|---|---|
20130128757 | NON-INTRUSIVE IN-BAND LINK COST ESTIMATION IN MULTIHOP NETWORKS - In a wireless multi-hop network, packet routing paths are determined for a first node device based on passive measurement of data messages over a wireless link formed between the first node device and a neighboring second node device. The first node device transmits a first data message to the second node device via the wireless link. At least one of the first node device and the second node device monitors at least one transmission performance parameter corresponding to only a selected subset of frames of the first data message. The selected subset of frames has structural similarity to selected subsets of frames of other data messages communicated and monitored by other node devices of the network. A link cost associated with the wireless link is determined based on at least one transmission performance parameter value produced as a result of the monitoring, which can be used to update the packet routing paths. | 05-23-2013 |
Roger K. Alexander, Rockville, MD US
Patent application number | Description | Published |
---|---|---|
20080242374 | METHOD AND APPARATUS FOR TRANSPARENT INVOCATION AND TRANSPORT OF ENCRYPTED POSITION LOCATION DATA - In one embodiment, the disclosure relates to a method for locating a mobile terminal in a communication network. The method includes: receiving a request data frame for locating the mobile terminal; uniquely encoding at least a portion of the request data frame (at an LCS client); determining the location of the mobile terminal (by a PDE); communicating the location information of the mobile terminal in a response data frame having an encrypted portion; and decrypting the location information of the mobile terminal (at the LCS client). | 10-02-2008 |
20110035510 | Methods and Apparatus Related to an Adapter Between a Premise Network and an Advanced Metering Infrastructure (AMI) Network - A system described herein can include a first node within an advanced metering infrastructure (AMI) network. The first node can be configured to be installed within a portion of a meter device. The system can also include an adapter configured to function as a second node within the AMI network. The adapter can be configured to translate a signal defined based on a platform of a premise network into a signal defined based on a platform of the AMI network. The adapter can be configured to be a meter-independent device. | 02-10-2011 |
20140019397 | SYSTEM AND METHOD FOR EFFICIENT DATA COLLECTION IN DISTRIBUTED SENSOR MEASUREMENT SYSTEMS - Endpoint device, central data collection point, and associated methods for collecting data over a communication network between endpoints and the central collection point. Actual measurements from a sensor are obtained by the endpoint device at a relatively fine time granularity. The endpoint device generates reports for receipt by a central data collection point. The reports include regular reports containing a portion of the actual measurements representing sensor measurements at a relatively coarse time granularity, and exception reports, containing information representing one or more of the actual measurements that differ in frequency or granularity of regular report measurements. Each of the exception reports is generated in response to a determination that at least one of the actual measurements differs from a predicted value for that at least one of the one or more actual measurements by an amount that exceeds a pre-established limit. | 01-16-2014 |
20140097966 | System and Method for Support of One-Way Endpoints in Two-Way Wireless Networks - A sensor data collection system includes a plurality of sensors operatively coupled to a corresponding set of endpoints, the endpoints configured to communicate sensor data to a central data collection point via a data communication protocol. A proxy service-enabled endpoint facilitates interoperability with the data collection system for the benefit of endpoints that are otherwise incompatible with the data communication protocol. The endpoint includes a remote endpoint interface module configured to receive communications from at least one of the incompatible endpoints containing incompatible endpoint sensor data. A remote endpoint virtualization module operatively coupled to the remote endpoint interface module and associated with the at least one of the incompatible endpoints. The remote endpoint virtualization module is uniquely addressable according to a corresponding virtual endpoint address, and configured to store the incompatible endpoint sensor data and to communicate that data to the central data collection point via the data communication protocol. | 04-10-2014 |
20150208320 | DYNAMICALLY-SELECTABLE MULTI-MODAL MODULATION IN WIRELESS MULTIHOP NETWORKS - In a self-organizing wireless multihop network, each node device selects operation among short-range (SR) and long-range (LR) communication modes, among which the SR mode uses a higher data rate than the LR mode. Each node device advertises connectivity link availability for neighboring node devices, and selectively initiates a link in response to connectivity availability advertised by at least one neighboring node device. The availability advertising is performed in the SR and the LR communication modes, according to a periodicity that is dynamically-variable in response to prevailing circumstances in the local neighborhood. The link initiation is selectively performed in one of either the SR or the LR communication mode based on selection criteria that include data throughput performance associated with different neighboring node devices with which connectivity is available via a certain communication mode. | 07-23-2015 |
Stephen B. Alexander, Millersville, MD US
Patent application number | Description | Published |
---|---|---|
20090041471 | REMODULATING CHANNEL SELECTORS FOR WDM OPTICAL COMMUNICATION SYSTEMS - The present invention provides a remodulating channel selector for a wavelength division multiplexed optical communication system. The remodulating selector receives a WDM input signal, selects a particular optical channel from the WDM signal and places the information from the selected signal onto a newly-generated optical output signal. The wavelength of the output optical signal can be the same as or different from one of the optical channels which comprises the WDM input signal. When used in a WDM optical communication system with remodulators at the transmission input, the remodulating selectors provide complete control over the interfaces with optical transmitters and receivers, permitting use with a broad range of optical equipment. | 02-12-2009 |
20100329682 | REMODULATING CHANNEL SELECTORS FOR WDM OPTICAL COMMUNICATION SYSTEMS - The present invention provides a remodulating channel selector for a wavelength division multiplexed optical communication system. The remodulating selector receives a WDM input signal, selects a particular optical channel from the WDM signal and places the information from the selected signal onto a newly-generated optical output signal. The wavelength of the output optical signal can be the same as or different from one of the optical channels which comprises the WDM input signal. When used in a WDM optical communication system with remodulators at the transmission input, the remodulating selectors provide complete control over the interfaces with optical transmitters and receivers, permitting use with a broad range of optical equipment. | 12-30-2010 |
Stephen B. Alexander, Annapolis, MD US
Patent application number | Description | Published |
---|---|---|
20110013911 | HIGH-SPEED OPTICAL TRANSPONDER SYSTEMS - The present disclosure provides high-speed wavelength division multiplexing (WDM) transponders (e.g., 10 Gb/s, 40 Gb/s, 100 Gb/s, and beyond) that receive one or more optical signals and convert and/or remodulate the received optical signals onto a newly generated optical channel along with overhead processing/addition, forward error correction, and the like. In general, the transponders of the present invention include a client-side and a line-side, each with bi-directional optical transmission. The transponders provide an effective mechanism to support WDM networks that are transparent to the client-side. | 01-20-2011 |
20160080342 | SECURE ACCESS SYSTEMS AND METHODS TO NETWORK ELEMENTS OPERATING IN A NETWORK - A network element, configured to operate in a network to provide various network functions therein, includes a main processor communicatively coupled to a main memory, wherein the main processor is configured to perform Operations, Administration, Maintenance, and Provisioning (OAM&P) associated with the network element, wherein the main processor is accessible through one or more access techniques; and a supervisory plane comprising a secure processor and a secure memory communicatively coupled thereto, wherein the supervisory plane is separate from and communicatively coupled to the main processor and the main memory, the supervisory plane is configured to allow secure, direct access to the main processor and the main memory. | 03-17-2016 |
William Alexander, Rockville, MD US
Patent application number | Description | Published |
---|---|---|
20080213223 | Systemic viral/ligand gene delivery system and gene therapy - The present invention relates to gene transfer and gene therapy technology. More specifically, the invention provides compositions and methods for targeted virus delivery. The method utilizes a method of mixing the virus, which may be a recombinant virus which will express a protein of interest or a nucleic acid of interest, with a cell-targeting ligand, e.g., transferrin. The virus and ligand are mixed without crosslinkers or agents which would covalently bond the virus and ligand. This simple mixing causes less inactivation than chemically linking the ligand to the virus and therefore results in a more active therapeutic composition than obtained by methods which utilize crosslinking agents. | 09-04-2008 |
20090191261 | Antibody fragment-targeted immunoliposomes for systemic gene delivery - Nucleic acid-immunoliposome compositions useful as therapeutic agents are disclosed. These compositions preferably comprise (i) cationic liposomes, (ii) a single chain antibody fragment which binds to a transferrin receptor, and (iii) a nucleic acid encoding a wild type p53. These compositions target cells which express transferrin receptors, e.g., cancer cells. These compositions can be used therapeutically to treat persons or animals who have cancer, e.g., head and neck cancer, breast cancer or prostate cancer. | 07-30-2009 |