Patent application number | Description | Published |
20100269692 | Clean corona gas ionization for static charge neutralization - Clean corona gas ionization by separating contaminant byproducts from corona generated ions includes establishing a non-ionized gas stream having a pressure and flowing in a downstream direction, establishing a plasma region of ions and contaminant byproducts in which the pressure is sufficiently lower than the pressure of the non-ionized gas stream to prevent at least a substantial portion of the byproducts from migrating into the non-ionized gas stream, and applying an electric field to the plasma region sufficient to induce at least a substantial portion of the ions to migrate into the non-ionized gas stream. | 10-28-2010 |
20110095200 | Covering wide areas with ionized gas streams - Ion delivery manifolds with a gas transport channel, for receiving an ionized gas stream, and plural outlets that divide the gas stream into plural neutralization gas streams that are directed toward respective plural target regions are disclosed. At least generally equal ion distribution across the target regions is achieved by using different ion flow rates through the plural outlets. Methods of delivering plural neutralization streams to respective plural target regions include steps for receiving an ionized gas stream, for dividing the ionized gas stream into plural neutralization streams, and for directing the neutralization streams toward respective target regions. At least generally equal ion distribution across the target regions is achieved by differing the ion flow rates of the neutralization streams. | 04-28-2011 |
20120037001 | CLEAN CORONA GAS IONIZATION FOR STATIC CHARGE NEUTRALIZATION - Clean corona gas ionization by separating contaminant byproducts from corona generated ions includes establishing a non-ionized gas stream having a pressure and flowing in a downstream direction, establishing a plasma region of ions and contaminant byproducts in which the pressure is sufficiently lower than the pressure of the non-ionized gas stream to prevent at least a substantial portion of the byproducts from migrating into the non-ionized gas stream, and applying an electric field to the plasma region sufficient to induce at least a substantial portion of the ions to migrate into the non-ionized gas stream. | 02-16-2012 |
20120198995 | Clean Corona Gas Ionization For Static Charge Neutralization - Clean corona gas ionization by separating contaminant byproducts from corona generated ions includes establishing a non-ionized gas stream having a pressure and flowing in a downstream direction, establishing a plasma region of ions and contaminant byproducts in which the pressure is sufficiently lower than the pressure of the non-ionized gas stream to prevent at least a substantial portion of the byproducts from migrating into the non-ionized gas stream, and applying an electric field to the plasma region sufficient to induce at least a substantial portion of the ions to migrate into the non-ionized gas stream. | 08-09-2012 |
20130175459 | MULTI-SECTIONAL LINEAR IONIZING BAR AND IONIZATION CELL - A multi-sectional linear ionizing bar with at least four elements is disclosed. First, disclosed bars may include at least one ionization cell with at least one axis-defining linear ion emitter for establishing an ion cloud along the length thereof. Second, disclosed bars may include at least one reference electrode. Third, disclosed bars may include a manifold for receiving gas or air from a source and for delivering same past the linear emitter(s) such that substantially none of the gas/air flows into the ion cloud. Fourth, disclosed bars may include means for receiving the ionizing voltage and for delivering same to the linear emitter(s) to thereby establish the ion cloud. In this way, disclosed ionizing bars may transport ions from the plasma region toward a charge neutralization target without inducing substantial vibration of the linear emitter and without substantial contaminants from the gas/air flow reaching the linear emitter. | 07-11-2013 |
20130307405 | Linear Jet Ionizer - A multi-sectional linear ionizing bar with at least four elements is disclosed. First, disclosed bars may include at least one ionization cell with at least one axis-defining linear ion emitter for establishing an ion cloud along the length thereof. Second, disclosed bars may include at least one reference electrode. Third, disclosed bars may include a manifold for receiving gas or air from a source and for delivering same past the linear emitter(s) such that substantially none of the gas/air flows into the ion cloud. Fourth, disclosed bars may include means for receiving the ionizing voltage and for delivering same to the linear emitter(s) to thereby establish the ion cloud. In this way, disclosed ionizing bars may transport ions from the plasma region toward a charge neutralization target without inducing substantial vibration of the linear emitter and without substantial contaminants from the gas/air flow reaching the linear emitter. | 11-21-2013 |
20150250044 | LINEAR IONIZING BAR WITH CONFIGURABLE NOZZLES - Ionizing bars for delivering charged carriers to charge neutralization target objects may include an ion emitter for establishing an ion cloud of charge carriers in response to application of an ionizing voltage. Disclosed bars may also include a reference electrode that presents a non-ionizing electric field to urge ions to move away from the ion emitter. The disclosed bars may also include a manifold. The manifold may receive and divide gas into plural gas streams directed past the ion emitter in a pattern to thereby urge charge carriers toward the target. The manifold may have plural apertures with nozzled inserts received therein. At least some of the inserts may have at least one aperture through which gas may flow and the nozzle inserts may collectively direct the divided gas streams away from the manifold and toward the target in one or more predetermined patterns. | 09-03-2015 |
20150282286 | Silicon Based Charge Neutralization Systems - An embodiment of the invention provides a method for low emission charge neutralization, comprising: generating a high frequency alternating current (AC) voltage; transmitting the high frequency AC voltage to at least one non-metallic emitter; wherein the at least one non-metallic emitter comprises at least 70% silicon by weight and less than 99.99% silicon by weight; wherein the at least one emitter comprises at least one treated surface section with a destroyed oxidation layer; and generating ions from the at least one non-metallic emitter in response to the high frequency AC voltage. Another embodiment of the invention provides an apparatus for low emission charge neutralization wherein the apparatus can perform the above-described operations. | 10-01-2015 |
Patent application number | Description | Published |
20090002652 | Lithographic apparatus and device manufacturing method - In a lithographic projection apparatus, a structure surrounds a space between the projection system and a substrate table of the lithographic projection apparatus. A gas seal is formed between said structure and the surface of said substrate to contain liquid in the space. | 01-01-2009 |
20110001942 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A lithographic projection apparatus is disclosed in which a space between the projection system and the substrate is filled with a liquid. An edge seal member at least partly surrounds the substrate or other object on a substrate table to prevent liquid loss when edge portions of the substrate or other object are, for example, imaged or illuminated. | 01-06-2011 |
20110170077 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A lithographic projection apparatus is disclosed in which a space between the projection system and the substrate is filled with a liquid. An edge seal member at least partly surrounds the substrate or other object on a substrate table to prevent liquid loss when edge portions of the substrate or other object are, for example, imaged or illuminated. | 07-14-2011 |
20110228241 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - In a lithographic projection apparatus, a structure surrounds a space between the projection system and a substrate table of the lithographic projection apparatus. A gas seal is formed between said structure and the surface of said substrate to contain liquid in the space. | 09-22-2011 |
Patent application number | Description | Published |
20080218726 | Lithographic apparatus and device manufacturing method - Lithographic Apparatus and Device Manufacturing Method In a lithographic projection apparatus, a structure surrounds a space between the projection system and a substrate table of the lithographic projection apparatus. Gas is used between the structure and the surface of the substrate to contain liquid in the space. | 09-11-2008 |
20090290135 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A lithographic projection apparatus includes a support structure configured to hold a patterning device, the patterning device configured to pattern a beam of radiation according to a desired pattern; a projection system configured to project the patterned beam onto a target portion of a substrate; a substrate table configured to hold the substrate, the substrate table including a support surface configured to support an intermediary plate between the projection system and at least one of the substrate and an object positioned on the substrate table and not in contact with the at least one of the substrate and the object; and a liquid supply system configured to provide a liquid, through which the beam is to be projected, in a space between the projection system and the at least one of the substrate and the object. | 11-26-2009 |
20100182576 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A liquid supply system for an immersion lithographic projection apparatus is disclosed in which a space is defined between the projection system, a barrier member and a substrate. The barrier member is not sealed such that, during use, immersion liquid is allowed to flow out the space and between the barrier member and the substrate. | 07-22-2010 |
20130066240 | ULTRASOUND TRANSDUCER FOR SELECTIVELY GENERATING ULTRASOUND WAVES AND HEAT - In order to provide heating means for an ultrasonic application setup, adapted for heating a sample ( | 03-14-2013 |
20140368799 | LITHOGRAPHIC APPARATUS AND DEVICE MANUFACTURING METHOD - A liquid supply system for an immersion lithographic projection apparatus is disclosed in which a space is defined between the projection system, a barrier member and a substrate. The barrier member is not sealed such that, during use, immersion liquid is allowed to flow out the space and between the barrier member and the substrate. | 12-18-2014 |
Patent application number | Description | Published |
20090244291 | DYNAMIC OBJECT CLASSIFICATION - A camera system comprises an image capturing device and an object classification module connected to the image capturing device. The image capturing device has a field of view and produces image data representing an image of the field of view. The object classification module is operable to determine whether or not an object in an image is a member of an object class. The object classification module includes N decision steps configured in a cascade configuration, wherein at least one of the N decision steps is operable to (a) accept an object as a member of the object class, (b) reject an object as a member of the object class, and (c) call on a next step to determine whether or not an object is a member of the object class. | 10-01-2009 |
20090292750 | METHODS AND APPARATUS FOR AUTOMATIC ACCURACY- SUSTAINING SCALING OF BLOCK-FLOATING-POINT OPERANDS - A computer-implemented method performs an operation on a set of at least one BFP operands to generate a BFP result. The method is designed to reduce the risks of overflow and loss of accuracy attributable to the operation. The method performs an analysis to determine respective shift values for each of the operands and the result. The method calculates result mantissas by shifting the stored bit patterns representing the corresponding operand mantissa values by their respective associated shift values determined in the analysis step, performing the operation on shifted operand mantissas to generate preliminary result mantissa, and shifting the preliminary result mantissas by a number of bits determined in the analysis step. | 11-26-2009 |
20150092054 | CASCADING VIDEO OBJECT CLASSIFICATION - A camera system comprises an image capturing device and an object classification module connected to the image capturing device. The object classification module is operable to determine whether or not an object in an image is a member of an object class. The object classification module includes multiple decision steps configured in a cascade configuration, wherein at least one of the multiple decision steps is operable to (a) accept an object as a member of the object class, (b) reject an object as a member of the object class, and (c) call on a next step to determine whether or not an object is a member of the object class. | 04-02-2015 |
20150093035 | VIDEO OBJECT CLASSIFICATION WITH OBJECT SIZE CALIBRATION - A camera system comprises an image capturing device and an object classification module connected to the image capturing device. The object classification module is operable to determine whether or not an object in an image is a member of an object class. The object classification module includes multiple decision steps configured in a cascade configuration, wherein at least one of the multiple decision steps is operable to (a) accept an object as a member of the object class, (b) reject an object as a member of the object class, and (c) call on a next step to determine whether or not an object is a member of the object class. | 04-02-2015 |
Patent application number | Description | Published |
20110196912 | Establishing Common Interest Negotiation Links Between Consumers and Suppliers to Facilitate Solving a Resource Allocation Problem - A computer-implemented method includes communicating to a number of agents a first resource negotiation request that includes one or more first parameters each having a corresponding first range of acceptability. The method includes receiving first request responses from each of one or more capable agents each operable to fulfill at least one first parameter within the corresponding first range of acceptability. The method includes determining solution entities based on the first responses, each solution entity including one or more of the capable agents operable to fulfill the one or more parameters of the first request within the corresponding first ranges of acceptability, each capable agent operable to fulfill at least one first parameter within the corresponding first range of acceptability. The method includes communicating a second resource negotiation request to each capable agent in each determined solution entity, the second request including one or more second parameters each having a corresponding second range of acceptability. | 08-11-2011 |
20120246108 | EFFICIENT SOURCE OF INFEASIBILITY IDENTIFICATION IN TIMED AUTOMATA TRACES - A method for verifying the performance of a real-time system modeled as a timed automaton. An abstract model of the system is checked against an initial Linear Temporal Logic specification. If a path to an undesirable state is found, the counterexample is validated or invalidated using negative cycle detection. If a negative cycle is detected, optimization is undertaken to identify a minimal infeasible fragment in the negative cycle. The specification is then refined to eliminate usage of the minimal infeasible fragment, and the abstract model is then checked against the refined specification. | 09-27-2012 |
20140207720 | SYSTEM AND METHOD FOR ASYNCHRONOUS EXPLANATION AND PROPAGATION-BASED CONSTRAINT SOLVING - Embodiments of a system and method for asynchronous explanation and explanation-based constraint problem solving are generally described herein. In one or more embodiments, an apparatus includes an asynchronous constraint satisfaction problem solving module (ACSPSM), the ACSPSM can be executable by one or more processors. The ACSPSM can be configured to propagate at least one constraint to a plurality of variables by reducing a speculative propagation range of a first variable when a first value in the speculative propagation range of the first variable is in conflict with the constraint. The ACSPSM can be configured to update an explanation for the reduction in the speculative propagation range of the first variable, or backtrack when a choice of a second value for a second variable would result in the speculative propagation range of the first variable becoming empty. The ACSPSM can be multi-threaded. | 07-24-2014 |
20150150119 | FRAMEWORK FOR FINE-GRAIN ACCESS CONTROL FROM HIGH-LEVEL APPLICATION PERMISSIONS - A method for access control of an application feature to resources on a mobile computing device. An application is prepared for installation on the mobile computing device via a processor. An application permission associated with the application is identified. The application permission relates to access of resources of the mobile computing device. Restrictions associated with the application permission are determined. A set of mandatory access control rules are defined for the application permission based on the restrictions. The set of mandatory access control rules and the application permission are combined in a loadable mandatory access control policy module. The loadable mandatory access control policy module is stored in a memory of the mobile computing device, the loadable mandatory access control policy module capable of being enforced by an operating system of the mobile computing device. | 05-28-2015 |
Patent application number | Description | Published |
20080245958 | SYSTEM AND METHOD TO CREATE HAZE STANDARD - In one embodiment, a system to create a haze standard on a surface of an object, comprises a radiation targeting assembly that targets a radiation beam onto the surface of the object, a drive assembly to impart relative motion between the radiation targeting assembly and the surface of the object, and a controller to regulate the radiation targeting assembly to deliver radiation at a controlled power level to at least one portion of the surface, thereby forming at least one region having a known haze characteristic. | 10-09-2008 |
20110051132 | Method and apparatus for producing and Measuring dynamically focussed, steered, and shaped oblique laser illumination for spinning wafer inspection system - A method and apparatus for producing high frequency dynamically focused oblique laser illumination for a spinning wafer inspection system. The focus is changed by changing the beam direction incidence angle so as to bring focal spot onto the wafer surface. | 03-03-2011 |
20140071437 | Monitoring Incident Beam Position in a Wafer Inspection System - Methods, systems, and structures for monitoring incident beam position in a wafer inspection system are provided. One structure includes a feature formed in a chuck configured to support a wafer during inspection by the wafer inspection system. The chuck rotates the wafer in a theta direction and simultaneously translates the wafer in a radial direction during the inspection. An axis through the center of the feature is aligned with a radius of the chuck such that a position of the axis relative to an incident beam of the wafer inspection system indicates changes in the incident beam position in the theta direction. | 03-13-2014 |
20140118729 | Illumination Energy Management in Surface Inspection - The disclosure is directed to a system and method of managing illumination energy applied to illuminated portions of a scanned wafer to mitigate illumination-induced damage without unnecessarily compromising SNR of an inspection system. The wafer may be rotated at a selected spin frequency for scanning wafer defects utilizing the inspection system. Illumination energy may be varied over at least one scanned region of the wafer as a function of radial distance of an illuminated portion from the center of the wafer and the selected spin frequency of the wafer. Illumination energy may be further applied constantly over one or more scanned regions of the wafer beyond a selected distance from the center of the wafer. | 05-01-2014 |
20140328043 | Illumination Energy Management in Surface Inspection - The disclosure is directed to a system and method of managing illumination energy applied to illuminated portions of a scanned wafer to mitigate illumination-induced damage without unnecessarily compromising SNR of an inspection system. The wafer may be rotated at a selected spin frequency for scanning wafer defects utilizing the inspection system. Illumination energy may be varied over at least one scanned region of the wafer as a function of radial distance of an illuminated portion from the center of the wafer and the selected spin frequency of the wafer. Illumination energy may be further applied constantly over one or more scanned regions of the wafer beyond a selected distance from the center of the wafer. | 11-06-2014 |
Patent application number | Description | Published |
20080263749 | BANDLESS HEARING PROTECTION MUFFS - The present disclosure generally relates to devices for covering an ear, and more particularly to such devices that are self-attaching and used for sound optimization, such as noise reduction. More specifically, the present disclosure is directed to hearing protection muffs that comprise a sound attenuating cap, a self-attachment member for engaging the sound attenuating cap to the ear of a user, and optionally a sealing member. Advantageously, the muffs of the present disclosure have good sound attenuating properties and do not require a band or other external attachment device to secure the muffs to the ear. | 10-30-2008 |
20080264715 | Bandless hearing protector and method - A hearing protection device and method for a human ear. A plug member caps or enters ear canal, and may be shaped to conform to the external auditory meatus. The device is biased at least in part by a pressure pad to provide some force against the plug member. An optional handle may be provided to assist with temporarily pulling the plug member away from the ear canal or providing adjustment. An optional bow member clips about the pinna. The device may be adapted for use as an ear phone. | 10-30-2008 |
20100016787 | BODY CAVITY IRRIGATION DEVICE - A hand-held disposable body cavity irrigation device comprises a pump with an inlet and an outlet, a container for lavage fluid fastened removably to said pump, an applicator having an insertion tip, and divided longitudinally into an injection chamber with a first fitting and a drain chamber with a second fitting, and a first tube connecting said outlet to the first fitting wherein the first tube comprises at least one malleable element embedded longitudinally into an elastic wall, said inlet communicates with the lavage fluid within the container, and the drain chamber is disposed predominantly below the injection chamber and has at least one vent beyond the insertion tip. | 01-21-2010 |
20100113896 | DIAGNOSTIC DEVICE WITH DISPLAY MODULE AND LEVERAGED COMPONENT CONNECTIONS - The present invention provides an innovative means for efficient and secure component assembly and for ensuring secure electrical connections in a small diagnostics device where available space for fasteners is limited. In one embodiment, principles of leverage are employed to produce a force at a location where space is available. The force is transferred to a different location of the assembly where it is used to maintain secure connections between components. | 05-06-2010 |
Patent application number | Description | Published |
20080274907 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE - A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: | 11-06-2008 |
20090004753 | LABELING REAGENTS AND METHODS OF THEIR USE - The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: | 01-01-2009 |
20090047692 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 02-19-2009 |
20090081722 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. The acetic acid groups interact directly with the positively charged histidine residues of the affinity tag to effectively label and detect a fusion protein containing such an affinity tag when present in an acidic or neutral environment. | 03-26-2009 |
20120040380 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 02-16-2012 |
20120270757 | SITE-SPECIFIC LABELING OF AFFINITY TAGS IN FUSION PROTEINS - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. | 10-25-2012 |
20130090470 | OPTICALLY-DETECTABLE ENZYME SUBSTRATES AND THEIR METHOD OF USE - The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactmase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactmase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactmase or instructions for using the components in an assay. | 04-11-2013 |
20130102021 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE - A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: | 04-25-2013 |
20130337536 | Labeling Reagents and Methods of Their Use - The present disclosure is directed to a reactive ester agent capable of conjugating a reporter molecule to a carrier molecule or solid support. The reactive ester agent has the general formula: | 12-19-2013 |
20140038856 | Site-specific labeling of affinity tags in fusion proteins - The present invention provides methods and fluorescent compounds that facilitate detecting and labeling of a fusion protein by being capable of selectively binding to an affinity tag. The fluorescent compounds have the general formula A(B)n, wherein A is a fluorophore, B is a binding domain that is a charged chemical moiety, a protein or fragment thereof and n is an integer from 1-6 with the proviso that the protein or fragment thereof not be an antibody or generated from an antibody. The present invention provides specific fluorescent compounds and methods used to detect and label fusion proteins that contain a poly-histidine affinity tag. These compounds have the general formula A(L)m(B)n wherein A is a fluorophore, L is a linker, B is an acetic acid binding domain, m is an integer from 1 to 4 and n is an integer from 1 to 6. The acetic acid groups interact directly with the positively charged histidine residues of the affinity tag to effectively label and detect a fusion protein containing such an affinity tag when present in an acidic or neutral environment. | 02-06-2014 |
20150037834 | FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE - A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: | 02-05-2015 |
20150218379 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) - Disclosed herein are compounds, compositions, methods and kits for detecting pH in samples using pH-sensitive fluorescent dyes. The compounds disclosed herein are novel xanthene-derivative dyes comprising an aniline moiety with one or more electron donating groups, which dyes are for detecting pH in samples either in vitro or in vivo. Also described herein are processes for preparing said dyes for use in the disclosed compositions, methods and kits. | 08-06-2015 |
20150241438 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use - Disclosed herein are compounds, compositions, methods and kits for detecting pH in samples using pH-sensitive fluorescent dyes. The compounds disclosed herein are novel xanthene-derivative dyes comprising an aniline moiety with one or more electron donating groups, which dyes are for detecting pH in samples either in vitro or in vivo. Also described herein are processes for preparing said dyes for use in the disclosed compositions, methods and kits. | 08-27-2015 |
Patent application number | Description | Published |
20090035823 | Ligation-based synthesis of oligonucleotides with block structure - The present invention relates to a method of producing single-stranded nucleic acid molecules from oligo- or polynucleotides wherein each of said oligo- or polynucleotides has a predefined 5′ or 3′ terminus, comprising the steps of (a) annealing an adaptor oligonucleotide simultaneously or step by step to (aa) a first oligo- or polynucleotide; and (ab) a second oligo- or polynucleotide wherein the 5′-terminus of said adaptor oligonucleotide is complementary in sequence to the 5′ terminus of said first oligo- or polynucleotide and the 3′terminus of said adaptor molecule is complementary in sequence to the 3′ terminus of said second oligo- or polynucleotide; and optionally (a′) simultaneously with or subsequently to step (a) annealing at least one further adaptor oligonucleotide to free termini of said first or second oligonucleotides and to free termini of further oligo- or polynucleotides; (b) optionally filling in gaps between the neighbouring ends of said oligo- or polynucleotides; (c) ligating said oligo- or polynucleotides; and (d) removing said at least one adaptor oligonucleotide. In a preferred embodiment of the method of the invention, said single-stranded nucleic acid molecules represent a collection of nucleic acid molecules wherein either said first or said second oligo- or polynucleotide is invariable in sequence between all members of said collection of nucleic acid molecules. | 02-05-2009 |
20120237943 | METHOD FOR DIFFERENTIATION OF POLYNUCLEOTIDE STRANDS - Objective of the present invention is to provide a method for keeping of directional information in double-stranded DNA. We suggest to convert polynucleotide into a hybrid double-stranded DNA. One particular strand of this hybrid double-stranded DNA should be synthesised using at least one modified nucleotide. Thus, this particular strand would contain modified nucleotides along the whole length. Density of directional markers would not depend on the length of polynucleotides. Any internal fragments of the hybrid double-stranded DNA would have directional information. When it is necessary the modified strand may be easily degraded or separated from the other strand. It was found that such hybrid double-stranded DNA may be easily generated in a number of molecular biology tasks and may be used for molecular cloning, library preparation and strand separation. | 09-20-2012 |
20150072867 | ANALYSIS OF NUCLEIC ACID MOLECULES DISTRIBUTED ON A SURFACE OR WITHIN A LAYER BY SEQUENCING WITH POSITION IDENTIFICATION - The present invention describes a method for identification of areas of a sample from which nucleic acid molecules originate using labeling of said nucleic acid molecules by two-dimensionally distributed oligonucleotide markers. Further analysis of hybrids between the nucleic acid molecules and the oligonucleotide markers allow identification of the original position of the labelled nucleic acid molecules in the sample. | 03-12-2015 |
20150105299 | Method for Differentiation of Polynucleotide Strands - Objective of the present invention is to provide a method for keeping of directional information in double-stranded DNA. We suggest to convert polynucleotide into a hybrid double-stranded DNA. One particular strand of this hybrid double-stranded DNA should be synthesised using at least one modified nucleotide. Thus, this particular strand would contain modified nucleotides along the whole length. Density of directional markers would not depend on the length of polynucleotides. Any internal fragments of the hybrid double-stranded DNA would have directional information. When it is necessary the modified strand may be easily degraded or separated from the other strand. It was found that such hybrid double-stranded DNA may be easily generated in a number of molecular biology tasks and may be used for molecular cloning, library preparation and strand separation. | 04-16-2015 |
20150141269 | HYBRIDIZATION-BASED REPLICATION OF NUCLEIC ACID MOLECULES - The present invention provides methods for replication of nucleic acid molecules distributed on a surface or within a layer by transferring them to a target surface covered with oligonucleotides, and fixation of transferred molecules by hybridization to complementary sequences. | 05-21-2015 |
Patent application number | Description | Published |
20130103618 | DECISION MAKING WITH ANALYTICALLY COMBINED SPLIT CONDITIONS - Systems, methods, and other embodiments associated with decision making with analytically combined split conditions are provided. In one embodiment, a method for classifying data is provided. An input data sample is received for classification as belonging to one of two possible classes. The input data sample includes a set of attribute values. The method includes evaluating the set of attribute values with a tree function that defines a decision boundary of a classification tree. The tree function classifies an input data sample as belonging to one of the two possible classes based, at least in part, on the attribute values of the input data sample. In another embodiment parameters of the tree function are derived by applying a gradient descent parameter update rule to the training data samples. | 04-25-2013 |
20140101492 | ADAPTIVE PREVENTIVE MAINTENANCE FOR COMPUTING SYSTEMS - Systems, methods, and other embodiments associated with adaptively determining a preventive maintenance schedule based on historical system operation are described. The prognostic parameter values are continuously partitioned into a number of operating states based on observed maintenance costs associated with the prognostic parameter values. The operating states range from absolutely healthy, one or more degrees of degradation, to fully degraded. A system cost function is used as the discriminant function. The system cost function is an expected maintenance cost when a given preventive maintenance (PM) schedule is adopted. The system cost function calculates the expected cost based on the observed cost of operation in each of the operating states and a probability of the computing system being in each of the operating states as determined by the PM schedule. The PM schedule that minimizes the cost function is determined to be the optimal PM schedule. | 04-10-2014 |
20140379717 | TRIPOINT ARBITRATION FOR ENTITY CLASSIFICATION - Systems, methods, and other embodiments associated with tripoint arbitration for data classification are described. In one embodiment, a method includes receiving a query data point for classification, an arbiter point, a first set of classified data points belonging to a first class and a second set of classified data points belonging to a second class. A class-aggregated similarity metric for the query data point and each set is determined based, at least in part, on tripoint arbitration coefficients for data point pairs that include the query data point and a classified data point in the set, as calculated using the arbiter point. The query data point is classified based on a comparison of the similarity metric determined for the first set and the similarity metric determined for the second set. | 12-25-2014 |
20150294052 | ANOMALY DETECTION USING TRIPOINT ARBITRATION - Systems, methods, and other embodiments associated with anomaly detection using tripoint arbitration are described. In one embodiment, a method includes identifying a set of clusters that correspond to a nominal sample of data points in a sample space. A point z is determined to be an anomaly with respect to the nominal sample when, for each cluster, a tripoint arbitration similarity between data points in the cluster calculated with z as arbiter is greater than a threshold. | 10-15-2015 |
Patent application number | Description | Published |
20110255768 | Method and System for Automated Ball-Grid Array Void Quantification - A method and system for identifying voids in solder balls in a ball-grid array (BGA) using an image of the BGA include localizing an image of a solder ball on the BGA image, the solder ball image having a radius and having multiple points each having an image intensity, and producing a void-free model image of the solder ball based on the radius of the solder ball image, the void-free model image having multiple points each having an image intensity. The method and system also include computing a difference between the image intensities of the points of the solder ball image and the image intensities of the points of the void-free model image to produce a residual image, and identifying a void using the residual image. | 10-20-2011 |
20120019351 | SYSTEM AND METHOD FOR MONITORING COMPUTER SERVERS AND NETWORK APPLIANCES - A sensor board includes at least one sensor in communication with a controller having a single board address to facilitate sensor polling by standard, product-independent modules of a circuit board for a computer server or network appliance. Miniature low-cost sensor boards can be placed in multiple locations on circuit boards without the necessity of being specified and integrated into the circuit board during the design phase to reduce or eliminate associated design risks or delays. | 01-26-2012 |
20120131007 | System and Method for Publishing - Computer implemented system and method for publishing evaluated information comprising collecting one or more sets of data from one or more users, generating one or more sets of augmented collected data by augmenting the one or more sets of data collected from the one or more users, wherein the augmenting the one or more sets of data includes implementing a typesetting function configured to associate identifier information with the collected one or more sets of data, detecting a request from the one or more users, providing at least one additional user at least a portion of the augmented collected data, wherein at least a portion of the provided augmented collected data includes identifier data associated with the one or more users, and assigning a recognized number to the augmented collected data. | 05-24-2012 |
Patent application number | Description | Published |
20100244977 | MULTICHANNEL STRIPLINE BALUN - Systems and devices for transmitting radio frequency signals to and from radio frequency coils in magnetic resonance imaging systems are provided. In one embodiment, a balun for blocking induced radio frequency current on ground conductors of a multi-layer signal carrier includes first and second insulative elements disposed on first and second sides of the signal carrier, respectively, a conductive layer partially surrounding ends of each insulative element with a central region of each insulative element not surrounded by the respective conductive layer, first and second capacitive circuits coupled to the conductive layers of each respective insulative element in the central region thereof, vias extending through the signal carrier, and conductive material disposed in the vias electrically coupling a conductive layer on respective ends of the first and second elements with one another and with the ground conductors. | 09-30-2010 |
20110304422 | TRANSFORMER ASSEMBLY FOR A MAGNETIC RESONANCE IMAGING SYSTEM - A transformer assembly includes a substrate having a first surface and an opposing second surface, a first spiral wound inductive coil formed on the first surface, and a second spiral wound inductive coil formed on the first surface; the first and second spiral wound inductive coils forming a double spiral arrangement on the first surface such that the first coil is inductively coupled to the second coil. An RF coil including the transformer assembly and a method of fabricating the transformer assembly are also described. | 12-15-2011 |
20120001715 | TRANSFORMER ASSEMBLY FOR A MAGNETIC RESONANCE IMAGING SYSTEM - A transformer assembly includes a substrate having a first surface and an opposing second surface, a first spiral wound inductive coil formed on the first surface, a second spiral wound inductive coil formed on the first surface, and a third spiral wound inductive coil formed on the first surface, the first, second and third spiral wound inductive coils forming a triple spiral arrangement on the first surface such that the first coil is inductively coupled to the second coil and the third coil. An RF coil including the transformer assembly and a method of fabricating the transformer assembly are also described. | 01-05-2012 |
20120007601 | INDUCTOR ASSEMBLY FOR A MAGNETIC RESONANCE IMAGING SYSTEM - An inductor assembly includes an electrical conductor having a first end and an opposite second end, and a plurality of turns, each turn having a first lobe and a second lobe, the electrical conductor being formed into a lemniscate shape. A Radio Frequency (RF) coil including the lemniscate shaped inductor and a Magnetic Resonance Imaging (MRI) system including the lemniscate shaped inductor are also described herein. | 01-12-2012 |
Patent application number | Description | Published |
20100308934 | INVISIBLE BALUN AND METHOD OF MAKING SAME - An apparatus and method for reducing stray magnetic fields include a decoupling circuit includes a balun that comprises a transmission line. The transmission line includes a first spiral positioned substantially parallel to a first plane, the first spiral emanating from a inner portion of the first spiral in a first spiral direction. The transmission line also includes a second spiral positioned substantially parallel to the first plane, the second spiral emanating from a inner portion of the second spiral in the first spiral direction, wherein the inner portion of the first spiral is electrically coupled to the inner portion of the second spiral, and wherein the transmission line comprises a signal line and a ground line. The balun further comprises a first capacitor electrically coupled to the transmission line. | 12-09-2010 |
20110267061 | QUARTER WAVE BALUN FOR MAGNETIC RESONANCE IMAGING SYSTEMS - A balun assembly includes a body portion having an opening extending therethrough, the opening sized to receive at least one radio-frequency (RF) cable therethrough, the RF cable transmitting a signal therethrough a signal having a wavelength, and a balun disposed within the body portion, the balun being folded to form a plurality of layers, the combined length of the layers being approximately equal to a quarter wavelength of the signal transmitted through the RF cable. A method of fabricating a balun assembly and an MRI system including a balun are also provided. | 11-03-2011 |
20110267165 | INDUCTOR ASSEMBLY FOR A MAGNETIC RESONANCE IMAGING SYSTEM - An inductor assembly includes a substrate having a first surface and an opposing second surface, a first spiral electrical conductor formed on the first surface, a second spiral electrical conductor formed on the second surface, at least one opening extending through the first and second surfaces, and a metallic pin configured to be inserted in the opening, the pin coupling the first conductor to the second conductor. An RF coil including the inductor assembly and a method of fabricating an inductor assembly are also described. | 11-03-2011 |