Agnew, US
Brett Agnew, West Des Moines, IA US
Patent application number | Description | Published |
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20150100518 | ADMINISTERING A CYCLE-BASED COLLARED INVESTMENT OPTION - A system for administering a cycle-based collared investment option may include a processor, memory, and an application stored in memory. The application may be executable by the processor to receive a cycle order. The cycle order may include investment data and a plurality of cycle parameters. The application may further by executable by the processor to send a derivative contract transaction request to a hedge advisor. The derivative contract transaction may be based on the investment data and cycle parameters. The application may further by executable by the processor to receive a daily market value corresponding to a held derivative contract from the hedge advisor. The application may further by executable by the processor to calculate a cycle interim value rate of return. The cycle interim value may be calculated by applying a predetermined formula that accounts for the daily market value received from the hedge advisor. | 04-09-2015 |
Brian Agnew, Eugene, OR US
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20090017546 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE - The present invention provides novel reactive fluorescent compounds that incorporate stable isotopic (deuterium, 13-carbon, 15-nitrogen, 18-oxygen) substitutions. The invention includes the use of these compounds, in combination with non-isotopically substituted analogs, for the purification, identification and relative quantification of proteins, peptides, saccharides, metabolites, and other biologically important compounds by combining liquid chromatography (LC) and mass spectrometry (MS). Fluorescent labeling of target compounds in this manner provides orders-of-magnitude sensitivity enhancement over traditional stable isotope labels, and also affords the possibility of simultaneous multiplexed analysis due to the multiwavelength nature of different fluorophores. | 01-15-2009 |
20100009381 | Compositions and methods for detection and isolation of phosphorylated molecules - The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified. | 01-14-2010 |
20100081203 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE - The present invention provides novel reactive fluorescent compounds that incorporate stable isotopic (deuterium, 13-carbon, 15-nitrogen, 18-oxygen) substitutions. The invention includes the use of these compounds, in combination with non-isotopically substituted analogs, for the purification, identification and relative quantification of proteins, peptides, saccharides, metabolites, and other biologically important compounds by combining liquid chromatography (LC) and mass spectrometry (MS). Fluorescent labeling of target compounds in this manner provides orders-of-magnitude sensitivity enhancement over traditional stable isotope labels, and also affords the possibility of simultaneous multiplexed analysis due to the multiwavelength nature of different fluorophores. | 04-01-2010 |
20100311063 | METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS - The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label. Other methods are provided that include a Staudinger ligation between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent comprising a substituted triarylphosphine attached to a label. Such methods do not require fixation and denaturation and therefore can be applied to the labeling of nucleic acid polymers in living cells and in organisms. Also provided are methods for measuring cellular proliferation. In these methods, the amount of label incorporated into the DNA is measured as an indication of cellular proliferation. The methods of the invention can be used in a wide variety of applications including clinical diagnosis of diseases and disorders in which cellular proliferation is involved, toxicity assays, and as a tool for the study of chromosomes' ultrastructures. | 12-09-2010 |
20110021372 | Compositions and methods for detection and isolation of phosphorylated molecules - The present invention relates to phosphate-binding compounds that find use in binding, detecting and isolating phosphorylated target molecules including the subsequent identification of target molecules that interact with phosphorylated target molecules or molecules capable of being phosphorylated. A binding solution is provide that comprises a phosphate-binding compound, an acid and a metal ion wherein the metal ion simultaneously interacts with an exposed phosphate group on a target molecule and the metal chelating moiety of the phosphate-binding compound forming a bridge between the phosphate-binding compound and a phosphorylated target molecule resulting in a ternary complex. The binding solution of the present invention finds use in binding and detecting immobilized and solubilized phosphorylated target molecules, isolation of phosphorylated target molecules from a complex mixture and aiding in proteomic analysis wherein kinase and phosphatase substrates and enzymes can be identified. | 01-27-2011 |
20110171736 | FLUORESCENT ISOTOPE TAGS AND THEIR METHOD OF USE - The present invention provides novel reactive fluorescent compounds that incorporate stable isotopic (deuterium, 13-carbon, 15-nitrogen, 18-oxygen) substitutions. The invention includes the use of these compounds, in combination with non-isotopically substituted analogs, for the purification, identification and relative quantification of proteins, peptides, saccharides, metabolites, and other biologically important compounds by combining liquid chromatography (LC) and mass spectrometry (MS). Fluorescent labeling of target compounds in this manner provides orders-of-magnitude sensitivity enhancement over traditional stable isotope labels, and also affords the possibility of simultaneous multiplexed analysis due to the multiwavelength nature of different fluorophores. | 07-14-2011 |
20110207171 | OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS - The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention. | 08-25-2011 |
20120027846 | ANTI-VIRAL AZIDE CONTAINING COMPOUNDS - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 02-02-2012 |
20120028244 | Anti-Viral Azide Containing Compounds - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 02-02-2012 |
20120028335 | ANTI-VIRAL AZIDE-CONTAINING COMPOUNDS - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a human immunodeficiency virus with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 02-02-2012 |
20120301894 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS - Provided in certain embodiments are new methods for forming azido modified biomolecule conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided methods for enzymatically labeling a biomolecules with an azide group. | 11-29-2012 |
20130089884 | Protein Modification from the Oxidation of Clickable Polyunsaturated Fatty Acid Analogs - Clickable polyunsaturated fatty acid analogs, methods of using these analogs and kits comprising these analogs. | 04-11-2013 |
20130209364 | Anti-Viral Azide Containing Compounds - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 08-15-2013 |
20130209550 | Anti-Viral Azide Containing Compounds - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 08-15-2013 |
20140065605 | METHODS AND COMPOSITIONS FOR LABELING NUCLEIC ACIDS - The present invention relates to methods for the labeling of nucleic acid polymers in vitro and in vivo. Certain methods are provided that include a [3+2] cycloaddition between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent attached to a label. Other methods are provided that include a Staudinger ligation between a nucleotide analogue incorporated into a nucleic acid polymer and a reagent comprising a substituted triarylphosphine attached to a label. Such methods do not require fixation and denaturation and therefore can be applied to the labeling of nucleic acid polymers in living cells and in organisms. Also provided are methods for measuring cellular proliferation. In these methods, the amount of label incorporated into the DNA is measured as an indication of cellular proliferation. The methods of the invention can be used in a wide variety of applications including clinical diagnosis of diseases and disorders in which cellular proliferation is involved, toxicity assays, and as a tool for the study of chromosomes' ultrastructures. | 03-06-2014 |
20140206848 | OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS - The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention. | 07-24-2014 |
20140336079 | LABELING AND DETECTION OF NUCLEIC ACIDS - Provided in certain embodiments are new methods for forming azido modified nucleic acid conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided methods for enzymatically labeling nucleic acids with an azide group. | 11-13-2014 |
20140377837 | OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS - The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention. | 12-25-2014 |
20150017703 | METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES - Methods of using viruses labeled with alkyne-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to increase the infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an alkyne-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The viruses labeled with alkyne-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 01-15-2015 |
20150051096 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS - Provided in certain embodiments are new methods for forming azido modified biomolecule conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided methods for enzymatically labeling a biomolecules with an azide group. | 02-19-2015 |
20150246146 | METHODS AND COMPOSITIONS FOR ENZYME-MEDIATED SITE-SPECIFIC RADIOLABELING OF GLYCOPROTEINS - Provided herein are methods, compositions and kits for use in the site-specific labeling of glycoproteins comprising a combination of enzyme-mediated incorporation of modified sugars comprising a chemical handle and cycloaddition chemistry with a labeling molecule comprising a reactive group, a metal ion chelator, and/or a fluorophore. | 09-03-2015 |
20150374723 | Anti-Viral Azide Containing Compounds - Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 12-31-2015 |
Brian Agnew, Sharonville, OH US
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20140286756 | DEVICE, SYSTEM AND METHOD FOR PREVENTING LEAKAGE IN A TURBINE - A turbine disk and blade assembly comprises a turbine disk including a plurality of disk posts extending radially therefrom and a plurality of disk slots between adjacent disk posts. The turbine disk is of a first material having a first coefficient of thermal expansion. The assembly further comprises a plurality of turbine blades. One of the turbine blades is received in each disk slot. The turbine blades are of a second material having a second coefficient of thermal expansion. The assembly further comprises a plurality of seal plates, wherein one of the seal plates is positioned in each disk slot radially inward of the turbine blade. The seal plates are of a material having a coefficient of thermal expansion substantially similar to that of either the disk posts or the turbine blade. | 09-25-2014 |
Brian Agnew, Eugen, OR US
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20100261181 | LABELING AND DETECTION OF NUCLEIC ACIDS - Provided in certain embodiments are new methods for forming azido modified nucleic acid conjugates of reporter molecules, carrier molecules or solid support. In other embodiments are provided methods for enzymatically labeling nucleic acids with an azide group. | 10-14-2010 |
Brian Agnew, Carlsbad, CA US
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20150037288 | METHODS FOR INCREASING THE INFECTIVITY OF VIRUSES - Methods of using viruses labeled with alkyne-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to increase the infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an alkyne-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The viruses labeled with alkyne-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome. | 02-05-2015 |
Brian Michael Agnew, Harrison, OH US
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20090000152 | Ski Boot - A ski boot is provided that includes an outer shell, an inner liner disposed within the outer shell and a functional shoe insertable into and removable from the inner liner by means of a rearforward to forward manner. | 01-01-2009 |
Brooks Alexander Agnew, Concord, NC US
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20130139626 | Power-economizing, integral electric vehicle drive mechanism with independent rear suspension for an electric vehicle with a multi-speed transmission capable of multiplying the torque of the electric motor at low speeds - The invention is an electric vehicle subassembly that has a drive with a front wheel drive multi-speed transmission with independent suspension mounted in the rear of the vehicle. The front wheel drive transmission is not steerable. The invention is also an electric vehicle drive subassembly with a drive having an electric motor, an input shaft of a multi-speed transmission, a driven gear cluster, a differential, and the axles of the vehicle all arranged in parallel. The invention also comprises methods for efficiently manufacturing such electric vehicles. | 06-06-2013 |
20130140882 | Kinetic Energy Recovery System to recharge the traction storage device of an electric vehicle through inertial differentials between a static mass and the lateral motions of a vehicle in motion. - A Kinetic Energy Recovery System to recharge the traction storage device of an electric vehicle through inertial differentials between a static mass and the lateral motions of a vehicle in motion. A modular machine made of an eccentric mass, which tends to remain motionless, against which the vehicle moves, forming the kinetic energy to turn that eccentric wheel, which in turn drives a series of ratios of shafts to generate electricity. Further, this generated electricity is rectified and regulated to the correct voltage to recharge the storage device on board that electric vehicle. | 06-06-2013 |
20130141226 | Automobile Telemetry for Data, Text, and Video Communication - The present invention comprises an automobile instrument display comprised of electronic hardware and software, with the display having a graphical user interface which is a screen located in place of at least one of an instrument on an instrument panel of a vehicle which is required for normal vehicle operation. The present invention also comprises an automobile-based electronic receiver and display that allows graphic or text information to be received and displayed to the operator of an automobile. The present invention also comprises an automobile-based data output device having a display capable of displaying to the operator of the automobile scalable electronic information that is downloaded into or transmitted to the automobile. | 06-06-2013 |
20130328348 | Integral solar panel system for an electric vehicle - Integral solar panel for an electric vehicle to recharge the traction battery pack. An integrally installed electronic solar panel array that is capable of fully recharging an automobile with energy obtained from sunlight or other wavelengths of ambient energy. Such an energy collecting panel is modular and may be removed or replaced with common tools. Further, such a collecting panel is non-glass, shatterproof, and non-glare. Further still, such a solar panel is designed to provide an isolated source of power to directly recharge the main traction storage device, such as a battery or a capacitor. | 12-12-2013 |
20150283889 | REAR CARRIAGE STRUCTURE FOR AN ELECTRIC VEHICLE - An electric vehicle traction drive assembly includes a variable-speed electric motor for providing the torque. A multi-speed transaxle multiplies the torque of the electric motor through the vehicle operator's selection between more than one gear ratio. An adapter mechanically couples the motor and the transaxle to integrate the motor with the transaxle keeping an output shaft of the motor center-aligned with an input shaft of the transaxle. | 10-08-2015 |
Carl Agnew, West Lafayette, IN US
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20120130470 | STENT WITH PROTECTED BARBS - An endoluminal prosthesis is described and comprises a stent ( | 05-24-2012 |
20120157880 | CORING TISSUE BIOPSY NEEDLE AND METHOD OF USE - Biopsy devices and methods are provided for collecting a sufficiently-sized tissue sample from a region at a known distance by boring into the sample region using simultaneous axial and rotational movement and providing a reduced risk of: over-passing or under-passing the sample sought, injury and trauma to the surrounding tissue area, having to stick the patient more than once, sample contamination, and the user's exposure to sharps. | 06-21-2012 |
20130023981 | BARBED ANCHOR - An endoluminal prosthesis includes a support structure including a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body. The anchor body can fit at least partially about, and can conform to the first strut, second strut, and the apex. A curved portion of the anchor and the curvilinear portion of the support structure can be co-formed, resulting in a secure interference fit so that welding, soldering, or other joining mechanisms can be avoided. Cutouts can be formed along the curved portion of the anchor to relieve stress or strain during the co-forming process. | 01-24-2013 |
Carson E. Agnew, Vienna, VA US
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20080268836 | Space-Based Network Architectures for Satellite Radiotelephone Systems - A space-based network for a satellite radiotelephone system includes at least one receive-only satellite and at least one transmit satellite. The transmit satellite can be a transmit-only satellite or a transmit and receive satellite. The receive-only satellite(s) are configured to receive wireless communications from a radiotelephone at a location over a satellite frequency band. The transmit satellite(s) are configured to transmit wireless communications to the radiotelephone at the location over the satellite frequency band. By providing at least one receive-only satellite and at least one transmit satellite, space-based networks can offer a significant link margin, without the need to undesirably burden the radiotelephones themselves to achieve this link margin. | 10-30-2008 |
Charles Agnew, Los Angeles, CA US
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20120222322 | String holder for use with concrete masonry units (CMU's) and bricks - A Masonry Line Stabilizing Apparatus for use with CMU's and Bricks incorporates an elongate piece of metal with biasing faces, which secure a string line longitudinally through a string stabilizing lip. | 09-06-2012 |
Charles Agnew, West Lafayette, IN US
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20110087234 | SYSTEM AND METHOD FOR INTRODUCING MULTIPLE MEDICAL DEVICES - A method and apparatus for introducing a first elongate medical device and short wire guide that are coupled together into a work site and remotely disconnecting them within the work site such that a secondary device comprising a catheter member can be introduced over the wire guide to the work site, and/or a second wire guide can be introduced to the work site via a passageway of the primary access device. A separating member may be provided to remotely separate the wire guide from the elongate medical device. A system of indicia, such as radiopaque or viewable markers, permits the operator to monitor the relative alignment of the devices within the work site to determine when uncoupling has occurred. In one example of the method, a wire guide and primary access device (e.g., a sphincterotome) is coupled to the wire guide and introduced via a duodenoscope into the biliary system. After performing a first medical operation, the devices are uncoupled with the wire guide being left within the biliary system such that a secondary access device, such as a balloon, biopsy device, stent delivery catheter, dilator, etc., can be introduced to perform a second medical operation without a traditional over-the-wire exchange being required. In another example of the method, a prosthesis, such as a valve or stent, is placed within the work site coupled to a wire guide which is remotely disconnected within the work site and a secondary device, such as a dilation balloon or second prosthesis, is introduced into the work site after the first delivery system is removed. | 04-14-2011 |
Charlie Agnew, West Lafayette, IN US
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20140243615 | Medical Devices, Systems, and Methods for the Visualization and Treatment of Bodily Passages - Medical devices are described herein. More particularly, the disclosure relates to medical devices, systems, and methods for the visualization and treatment of bodily passages, such as an airway, sinus cavity, or sinus passages. An exemplary medical device comprises an elongate member, an actuator moveable between an actuator first position and an actuator second position, and a wire member. The elongate member has a first straight, or substantially straight configuration, when the actuator is in the actuator first position and a second curved configuration when the actuator is in the actuator second position. | 08-28-2014 |
Daniel D. Agnew, Lapeer, MI US
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20090260906 | Automotive Vehicle Engine Apparatus - An automotive vehicle engine apparatus includes an air intake system. In a further aspect of the present application, an automotive vehicle engine apparatus includes an air intake manifold, an air box and an air scoop. Another aspect of the present application employs an air intake shaker and a supercharger. A method of manufacturing and/or operating an air intake system is also provided. | 10-22-2009 |
Daniel E. Agnew, Madison, WI US
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20140073022 | PRODUCTION OF POLYHYDROXYALKANOATES WITH A DEFINED COMPOSITION FROM AN UNRELATED CARBON SOURCE - Cells and methods for producing polyhydroxyalkanoates. The cells comprise one or more recombinant genes selected from an R-specific enoyl-CoA hydratase gene, a PHA polymerase gene, a thioesterase gene, and an acyl-CoA-synthetase gene. The cells further have one or more genes functionally deleted. The functionally deleted genes include such genes as an enoyl-CoA hydratase gene, a 3-hydroxyacyl-CoA dehydrogenase, and a 3-ketoacyl-CoA thiolase gene. The recombinant cells are capable of using producing polyhydroxyalkanoates with a high proportion of monomers having the same carbon length from non-lipid substrates, such as carbohydrates. | 03-13-2014 |
David Agnew, Clarkston, MI US
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20140172263 | SAFETY INTERLOCK SYSTEM WITH SIDE AREA DETECTION - A safety interlock system for a motor vehicle has a plurality of object sensors capable of detecting the presence of an object such as a pedestrian in the danger zone at the front of the vehicle, rear the vehicle or proximate to the wheels. A door sensor is capable of detecting the open or closed state of the vehicle doors. An interlock override switch and a control circuit are also connected to the safety interlock system. The control circuit is capable of activating the safety interlock system when a door open signal is received. When the safety interlock system is activated the control circuit may engage the brakes to prevent motion of the vehicle if an object signal is received from the object sensor. | 06-19-2014 |
20150161458 | EMERGENCY VEHICLE DETECTION WITH DIGITAL IMAGE SENSOR - A display system for a vehicle comprises a display mounted within a passenger compartment of a vehicle and at least one camera mounted to the vehicle and facing at least partially in a rear direction. The display shows the images recorded by the camera(s) to provide a rear view for the driver of the vehicle. An ECU is controllably connected to the display screen and the at least one camera to analyze an image from the at least one camera to detect when an object in the image is an emergency vehicle; and to activate an alert on the display when an emergency vehicle is detected. | 06-11-2015 |
20160096549 | VEHICLE TRAILER CONTROL SYSTEM WITH WIRELESS CAPABILITY - A method of controlling a backing system for a vehicle and trailer assembly comprises initiating a backing system mode with an electronic control unit (ECU) for the backing system when a start system input is received from a control device. At least one input is received by the ECU from the control device which includes information about a desired vehicle action. The ECU interprets from the at least one input the desired vehicle action and calculates a required vehicle response to achieve the desired vehicle action. The ECU then sends a request to at least one vehicle system to perform the calculated vehicle response. | 04-07-2016 |
David L. Agnew, Clarkston, MI US
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20140172234 | GPS DATA FOR IMPROVING PEDESTRIAN PROTECTION - A pedestrian protection system from a vehicle utilizes GPS data to reduce the number of false positive detections for impacting an object determined to be a pedestrian. The GPS data is used to focus on area of increased and/or decreased pedestrian presence to alter a reaction threshold for the vehicle. Additionally, the GPS data can be used for more accurate analysis of the likelihood of an impact. | 06-19-2014 |
David Leslie Agnew, Clarkston, MI US
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20130096820 | VIRTUAL DISPLAY SYSTEM FOR A VEHICLE - A display system for a vehicle comprises display screens mounted within a passenger compartment of a vehicle. Cameras are mounted on the exterior of the vehicle corresponding to the positions of the display screens. A sensor(s) is directed toward a driver for the vehicle to sense a driver eye position. An ECU for the display system analyzes the driver eye position and determines a line of sight. An image from the camera is displayed on the display screen that corresponds to the driver's line of sight. Consequently, rather than the vehicle obstructing the driver's view the display system provides images to the driver of what would be seen if the vehicle body was not there. Thus, the display system provides virtually transparent portions of the vehicle body which widens the field of view provided to the driver. | 04-18-2013 |
20140168001 | NEGATIVE OBSTACLE DETECTION WITH STEREO CAMERA AND LONG RANGE RADAR - A negative obstacle detection system for a vehicle comprises a stereo camera mountable to the vehicle to provide a forward facing image and a long range radar mountable to the vehicle to emit a signal in a forward direction from the vehicle. An electronic control unit receives data from the stereo camera and the long range radar to determine if a negative obstacle may be located in a forward proximity to the vehicle. | 06-19-2014 |
20140190759 | AUTONOMOUS VEHICLE BRAKING AND STEERING SYSTEM - A steering system for a vehicle includes a front wheel supported for rotation about a first axis and a pivot axis transverse to the first axis and spaced inboard of a centerline of the front wheel. The front wheel is movable about the pivot axis to change direction of the vehicle. A brake coupled to the front wheel provides braking rotation of the front wheel and a controller controls operation of the brake to generate a desired braking force in a direction determined to adjust a vehicle direction. | 07-10-2014 |
20150203109 | ROAD DEPARTURE PROTECTION SYSTEM - A safety system for a vehicle providing a road departure protection feature comprises a camera, mounted to the vehicle to provide a view of a driving direction of the vehicle, and an electronic control unit connected to the camera. The electronic control unit includes instructions for analyzing the image and comparing the roadway path to the predicted vehicle path. The electronic control unit determines a vehicle roadway departure is occurring when the predicted vehicle path differs from the roadway path by a predetermined threshold, and then determines at least one corrective action to return the vehicle path to the roadway path. The safety system sends instructions to apply at least one corrective action with at least an electronic stability control system. | 07-23-2015 |
20150210259 | METHOD FOR REDUCING REVERSE VEHICLE STOPPING DISTANCE USING BRAKE PRE-CHARGE - An automatic braking system for a vehicle is disclosed and includes an electronic brake system capable of applying wheel brakes to decelerate the vehicle and a controller. The controller includes instructions for maintaining the electronic brake system in a pre-charge condition when the vehicle is operating in a reverse gear, and applying the wheel brakes independent of a driver input. | 07-30-2015 |
20150210264 | REVERSE VEHICLE SPEED CONTROL USING ONLY THE BRAKE PEDAL - A vehicle operating system is disclosed that includes an accelerator pedal for generating an input proportional to a desired acceleration of a vehicle when the vehicle is in at least one of a plurality of forward gears and a brake pedal for generating an input for controlling application of vehicle brakes of the vehicle. The brake pedal is configured to generate a single input for controlling both acceleration of the vehicle and application of the vehicle brakes when the vehicle is in a reverse gear. | 07-30-2015 |
20150210279 | SYSTEM FOR ACCOMMODATING A PEDESTRIAN DURING AUTONOMOUS VEHICLE OPERATION - A collision avoidance system for a vehicle includes an electronic brake system capable of applying wheel brakes to decelerate the vehicle, a steering system capable of changing a steering angle for the vehicle, and a controller. The controller instructions for performing a pedestrian avoidance maneuver including at least one of steering the vehicle to the maximum available separation distance and braking the vehicle to the maximum safe speed while the vehicle is passing the pedestrian. | 07-30-2015 |
20150210280 | METHOD FOR MINIMIZING AUTOMATIC BRAKING INTRUSION BASED ON COLLISION CONFIDENCE - An automatic braking system for a vehicle includes an electronic brake system capable of applying wheel brakes to decelerate the vehicle and a controller. The controller includes instructions for detecting an object proximate to a vehicle with at least one sensor for a reverse collision avoidance system and determining a collision confidence value based upon the probability of collision with the object. The controller further includes instructions for determining a desired velocity profile of the vehicle that provides for deceleration of the vehicle. | 07-30-2015 |
20150258991 | METHOD AND SYSTEM FOR DISPLAYING PROBABILITY OF A COLLISION - A maneuvering assistance system for a vehicle determines a scalar field representing the probability of collision with an object at locations proximate to the vehicle with a controller located within the vehicle. The probability of collision is determined based on information received indicative of vehicle motion and the proximity of the object to the vehicle, and the field of collision probability is then communicated as a visual representation to an operator of the vehicle. | 09-17-2015 |
20160059889 | DIFFERENTIAL CONTROL USER INTERFACE FOR REVERSING VEHICLE AND TRAILER SYSTEM - A disclosed method of maneuvering a vehicle-trailer unit in reverse travel with a backing system includes, among other things, determining that the vehicle-trailer unit is backing up with an electronic control unit for the backing system. A current hitch angle is determined, which represents the relative angle between the vehicle and the trailer with the electronic control unit. A requested hitch angle rate of change versus distance traveled is calculated with the electronic control unit, wherein the requested hitch angle rate of change is based upon a input from a joystick control which provides a requested hitch angle rate of change signal value in proportion to the joystick position. A steering angle is calculated with the electronic control unit based upon the requested hitch angle rate of change, wherein the steering angle will allow movement of the vehicle-trailer unit in the reverse direction to obtain the requested hitch angle rate of change; and a request is sent to a steering system to provide the steering angle. | 03-03-2016 |
Deryk Shane Agnew, Plano, TX US
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20160088115 | PREEMPTIVE LOADING OF PROTECTED DATA FOR STREAMING MOBILE DEVICES - According to some embodiments, a proxy server populates a proxy server cache with first user content and sends the first user content to a secure client application executing on a user's mobile device. The proxy server determines a usage pattern based on a portion of the first user content consumed by the secure client application, prioritizes unrequested user content according to the usage pattern, and populates the proxy server cache with at least a portion of the unrequested user content based on priority. | 03-24-2016 |
Devin Agnew, Los Angeles, CA US
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20150312618 | Systems and Methods for Generating a Full-Motion Video Mosaic Interface for Content Discovery with User-Configurable Filters - A method for generating an interactive graphical user interface is performed at a server system remote from a client device. The server system receives, from the client device, user input selecting a first filter, and filters available video programming using one or more search conditions corresponding to the first filter, to identify a first plurality of videos that satisfy the one or more search conditions. The one or more search conditions include a criterion relating to a popularity metric for a social network. The server system generates a user interface that includes a first mosaic of selectable video tiles corresponding to the first plurality of videos. Respective videos of the first plurality of videos are played in respective video tiles of the first mosaic. The server system encodes the user interface as a video stream and transmits the video stream containing the user interface toward the client device for display. | 10-29-2015 |
Frank D. Agnew, Metairie, LA US
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20130132289 | OIL AND GAS INTEREST TRACKING SYSTEM - A system for managing oil and gas mineral interest comprising: a server; one or more databases operatively associated with the server for storing oil and gas mineral interest data; one or more computer terminals operatively associated with the server and the database; an owner registration module operatively associated with the server and the database; a beneficiary registration module operatively associated with the server and the database; an access control module operatively associated with the server and the database; an oil and gas mineral interest data registration module operatively associated with the server and the database; a data standardization module operatively associated with the server and the database; an update module operatively associated with the server and the database; and a surveillance process module operatively associated with the server and the database. | 05-23-2013 |
George Mcdowell Agnew, Tucson, AZ US
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20150365371 | Channels: Real Time, Internet Social Networking, Multichannel, Communication and Multimedia Sharing Application - Examples of use to explain the unique and innovative system and process: | 12-17-2015 |
Gerald P. Agnew, Waukesha, WI US
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20080304412 | Architecture for Optical Metro Ethernet Service Level Agreement (SLA) Management - A system for managing one or more service level agreements associated with a switched metro Ethernet network is disclosed and manages one or more service level agreements associated with a switched metro Ethernet network. The system also includes a service level agreement (SLA) management reporting system (MRS) and a performance engine (PE) data filter coupled to the SLA-MRS. Further, the system includes one or more network elements connected to the PE data filter, wherein the SLA-MRS is configured to receive performance data from the PE data filter and at least partially based on the performance data validate one or more customer claims regarding an SLA violation. | 12-11-2008 |
Heather Agnew, Pasadena, CA US
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20100009896 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Multi-ligand capture agents comprising two or more ligands are described, and related compositions, methods and systems. | 01-14-2010 |
20110263515 | CAPTURE AGENTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS - Multi-ligand capture agents comprising two or more ligands are described, and related compositions, methods and systems. | 10-27-2011 |
Heather Dawn Agnew, Culver City, CA US
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20120202219 | PSA CAPTURE AGENTS, COMPOSITIONS, METHODS AND PREPARATION THEREOF - Disclosed herein are novel synthetic prostate specific antigen (PSA)-targeted capture agents that specifically bind PSA. In certain embodiments, these PSA capture agents are biligand or triligand capture agents containing two or three target-binding moieties, respectively. | 08-09-2012 |
20130156692 | VEGF-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING - The present application provides biligand and triligand protein-catalyzed capture (PCC) agents that specifically bind VEGF, as well as the use of these capture agents as detection, diagnosis, and treatment agents. | 06-20-2013 |
20140256630 | VEGF-SPECIFIC CAPTURE AGENTS, COMPOSITIONS, AND METHODS OF USING AND MAKING - The present application provides biligand and triligand protein-catalyzed capture (PCC) agents that specifically bind VEGF, as well as the use of these capture agents as detection, diagnosis, and treatment agents. | 09-11-2014 |
20150093758 | PSA CAPTURE AGENTS, COMPOSITIONS, METHODS AND PREPARATION THEREOF - Disclosed herein are novel synthetic prostate specific antigen (PSA)-targeted capture agents that specifically bind PSA. In certain embodiments, these PSA capture agents are biligand or triligand capture agents containing two or three target-binding moieties, respectively. | 04-02-2015 |
John Agnew, Beaverton, OR US
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20140336796 | SKATEBOARD SYSTEM - Example embodiments may relate to a system, method, apparatus, and computer readable media configured for monitoring a user performing various athletic movements and generating performance characteristics based on the data corresponding to such athletic movements. Users may also be encouraged to participate in athletic challenges or competitions against other users or groups of users. In addition, athletic movement data for multiple persons can be collected at a central location, and subsequently displayed to a user at a desired remote location, so that the user can compare his or her athletic activities to others. | 11-13-2014 |
20150067811 | CONDUCTING SESSIONS WITH CAPTURED IMAGE DATA OF PHYSICAL ACTIVITY AND UPLOADING USING TOKEN-VERIFIABLE PROXY UPLOADER - A token-verifiable proxy uploader is disclosed. A token request may be transmitted from an end-user communication device for requesting an upload token from a hosted services server that is configured to authorize transmission of a first media file to a hosted proxy server. The upload token may be transmitted to the end-user communication device. Validation of the user of the end-user communication device may be conducted without the end-user device providing any credentials to the media sharing site and in which the end-user device is does not transmit any credentials specific to the media sharing site as part of the validation. The token validation call may be in response to the hosted proxy server receiving the upload token and either: (1) the first media file from the end-user communication device; or (2) a request from the end-user communication device to upload the first media file to the hosted proxy server. | 03-05-2015 |
Nathan K. Agnew, Richmond, TX US
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20100317005 | Modified Nucleotides and Methods for Making and Use Same - Labeled nucleotide triphosphates are disclosed having a label bonded to the gamma phosphate of the nucleotide triphosphate. Methods for using the gamma phosphate labeled nucleotide are also disclosed where the gamma phosphate labeled nucleotide are used to attach the labeled gamma phosphate in a catalyzed (enzyme or man-made catalyst) reaction to a target biomolecule or to exchange a phosphate on a target biomolecule with a labeled gamme phosphate. Preferred target biomolecules are DNAs, RNAs, DNA/RNAs, PNA, polypeptide (e.g., proteins enzymes, protein, assemblages, etc.), sugars and polysaccharides or mixed biomolecules having two or more of DNAs, RNAs, DNA/RNAs, polypeptide, sugars and polysaccharides moieties. | 12-16-2010 |
Rhonda L. Agnew, Anton, TX US
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20120046627 | NURSING PAD CLOTHING LINER - A nursing pad clothing liner for placing against a woman's breasts to protect from milk leakage. | 02-23-2012 |
Ryan Agnew, Bellevue, WA US
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20150093733 | SOFTWARE PRODUCT USING GAMING PROTOCOLS AND TECHNOLOGY TO HELP PEOPLE DEAL WITH CHRONIC CONDITIONS - A software product using gaming protocols and technology to help people deal with chronic conditions is described herein comprising four modules. The first module presents a therapeutic component to teach condition management skills. The second module presents a query component to assess various conditions. The third module presents an activities component to determine progress towards learning condition management skills. The fourth module presents a progression module to track that progress. Progress reports detailing the user's progress may be provided. | 04-02-2015 |
Sean Agnew, Thousand Oaks, CA US
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20110010242 | Targeting of Advertisements to Users of an Online Service - There is disclosed a server and local device that interface for selecting advertisements to be viewed by users of an online service based upon user activity. The local device preferably maintains a targeted activity list of activity identifiers and associated advertisements. The local device monitors the activity on the local device and compares the activity to the identifiers in the targeted activity list. If the activity matches one of the identifiers, the local device plays one or more advertisements. | 01-13-2011 |
Sean R. Agnew, Charlottesville, VA US
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20160061596 | Portable Optical Profilometer Device, System and Method - A hand-portable optical surface profilometer device can employ depth from defocus techniques to measure surface roughness in wide-area industrial processes. | 03-03-2016 |
Thomas J. Agnew, Dallas, TX US
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20130132289 | OIL AND GAS INTEREST TRACKING SYSTEM - A system for managing oil and gas mineral interest comprising: a server; one or more databases operatively associated with the server for storing oil and gas mineral interest data; one or more computer terminals operatively associated with the server and the database; an owner registration module operatively associated with the server and the database; a beneficiary registration module operatively associated with the server and the database; an access control module operatively associated with the server and the database; an oil and gas mineral interest data registration module operatively associated with the server and the database; a data standardization module operatively associated with the server and the database; an update module operatively associated with the server and the database; and a surveillance process module operatively associated with the server and the database. | 05-23-2013 |
William Agnew, Salisbury, MD US
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20150313757 | EYE DROPPER - An eye dropper bottle including a notch for resting on the bridge of a nose is provided. The eye dropper bottle may include a curved neck with a nozzle. The nozzle may be oriented at an angle relative to the bottle. A user may place the notch on the bridge of the nose so that the nozzle is disposed over the eye. The user may then squeeze the bottle to dispense the liquid into the eye. | 11-05-2015 |
20150335869 | OCULAR TREATMENT USING MEDICATED ABSORBENT PAD - A sterile cotton fiber pad to deliver generic prescription medication transdermally through the eyelid is provided. The sterile absorbent pad may contain liquid medication and may be applied to the thin, highly vascularized tissue of the eyelids by direct application. | 11-26-2015 |
William S. Agnew, Atlanta, GA US
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20160046930 | METHODS OF SEQUENCING NUCLEIC ACIDS IN MIXTURES AND COMPOSITIONS RELATED THERETO - This disclosure relates to analyzing the end-to-end sequence and the relative distributions in heterogeneous mixtures of polynucleotides and methods and enabling reagents related thereto. In certain embodiments this method relates to the complete full length sequencing and quantitative profiling of mRNAs present in the transcriptomes of cells or tissues of but not limited to, higher multicellular organisms that possess interrupted genes subject to complex post-transcriptional RNA processing | 02-18-2016 |