52nd week of 2020 patent applcation highlights part 27 |
Patent application number | Title | Published |
20200399497 | WIRE COAT COMPOSITION AND A TIRE COMPRISING A WIRE COAT COMPOSITION - The invention relates to a wire coat rubber composition for coating metal wires in a tire, the rubber composition comprising from 60 to 100 phr of natural rubber, from 0 to 40 phr of synthetic polyisoprene, from 40 to 70 phr of oxidized carbon black, up to 5 phr of a resin and up to 8 phr of oil. The present invention also relates to a tire comprising such a wire coat composition. | 2020-12-24 |
20200399498 | TEXTILE COAT RUBBER COMPOSITION FOR A TIRE AND A TIRE COMPRISING A TEXTILE COAT RUBBER COMPOSITION - In accordance with the invention, a textile cord coat composition for a tire comprises from 70 to 90 phr cis 1,4-polyisoprene rubber, from 10 to 30 phr styrene butadiene rubber, from 25 to 45 phr carbon black, the latter comprising between 1 and 6 phr high surface area carbon black having a BET surface area of more than 700 m | 2020-12-24 |
20200399499 | POLYOLEFIN AND POLYVINYLPYRROLIDONE FORMULATION - A polyolefin-and-polyvinylpyrrolidone formulation comprising (A) an olefin-based (co)polymer, (B) a polyvinylpyrrolidone (co)polymer, and (C) an antioxidant. Also a method of making the composition; a crosslinked polyolefin product made by curing the composition; manufactured articles comprising a shaped form of the inventive formulation or product; and methods of using the inventive formulation, product, or articles. | 2020-12-24 |
20200399500 | Chemical Agent Resistant Coating Compositions - A chemical agent resistant coating composition can include a fluoropolymer, a dispersible acrylic resin, a flatting agent, and a hydrophobic additive. The coating composition can include at least 10 weight % of the flatting agent based on the total solids weight of the coating composition, and the flatting agent can include ground fiberglass, a hyperbranched (meth)acrylic resin, and an additional flatting agent. The hydrophobic additive can include a wax. When the composition is applied to a substrate and cured as a coating, the coating has an 85° gloss of less than 3.5, a water contact angle of greater than 80°, and desorbs a maximum of 180 micrograms of bis(2-chloroethyl) sulfide and a maximum of 40 micrograms of O-pinacolyl methylphosphonofluoridate, according to testing under MIL-PRF-32348. A method of preparing chemical agent resistant coating compositions and substrates at least partially coated with the chemical agent resistant coating compositions are also disclosed. | 2020-12-24 |
20200399501 | SEALANT COMPOSITION AND ZERO DISCHARGE IMPREGNATION PROCESS - A composition for an impregnation sealant for sealing metal castings and the like is provided. Also described is a zero discharge process of rinsing sealant from an impregnated article, separating sealant from the rinse water, and recycling the sealant and rinse water for reuse. | 2020-12-24 |
20200399502 | FILM, LIQUID COMPOSITION, OPTICAL ELEMENT, AND IMAGING APPARATUS | 2020-12-24 |
20200399503 | COMPOSITION FOR FORMING HARDCOAT LAYER, HARDCOAT FILM, ARTICLE AND IMAGE DISPLAY DEVICE HAVING HARDCOAT FILM, AND METHOD FOR MANUFACTURING HARDCOAT FILM - A composition for forming a hardcoat layer includes a polyorganosilsesquioxane; and a polymerization initiator, in which the polyorganosilsesquioxane has, at least, a siloxane constitutional unit containing an oxetanyl group and a siloxane constitutional unit containing an epoxy group and is represented by the General Formula (1), in the General Formula (1), Ra represents a group containing an oxetanyl group; Rb represents a group containing an epoxy group; Rc represents a monovalent substituent; Ra, Rb, and Rc each have a structure including none of an amide bond, a urea bond, and a urethane bond; p and q represent an integer equal to or greater than 1; r represents an integer equal to or greater than 0; p/q is equal to or greater than 1.0 and less than 99. | 2020-12-24 |
20200399504 | POLISHING AGENT FOR SYNTHETIC QUARTZ GLASS SUBSTRATE AND METHOD FOR POLISHING SYNTHETIC QUARTZ GLASS SUBSTRATE - A polishing agent for a synthetic quartz glass substrate. The polishing agent contains wet ceria particles and non-spherical silica particles. The wet ceria particles have an average primary particle diameter of 30 nm to 50 nm. The non-spherical silica particles have an average primary particle diameter of 80 nm to 120 nm. This provides a polishing agent for a synthetic quartz glass substrate, the polishing agent having high polishing rate and being capable of sufficiently reducing generation of defects due to polishing. | 2020-12-24 |
20200399505 | POLISHING COMPOSITION - The present invention provides a polishing composition with which polishing rates can be effectively improved and which is for polishing works to be polished. The polishing composition comprises water, abrasive grains, an oxidant, and a polishing accelerator. The polishing accelerator comprises at least one metal salt selected from the group consisting of alkali metal salts and alkaline-earth metal salts. | 2020-12-24 |
20200399506 | SEMICONDUCTOR DEVICE MANUFACTURING METHOD, CURABLE RESIN COMPOSITION FOR TEMPORARY FIXATION MATERIAL, FILM FOR TEMPORARY FIXATION MATERIAL, AND LAMINATED FILM FOR TEMPORARY FIXATION MATERIAL - Disclosed is a semiconductor device manufacturing method, including a preparation step of preparing a laminated body in which a supporting member, a temporary fixation material layer that generates heat upon absorbing light, and a semiconductor member are laminated in this order, and a separation step of irradiating the temporary fixation material layer in the laminated body with incoherent light and thereby separating the semiconductor member from the supporting member. | 2020-12-24 |
20200399507 | Linerless Water-Activated Water-Based Emulsion - Provided herein is a water-activated adhesive comprising an aqueous emulsion of vinyl acetate, polyvinyl alcohol, and glycerin. The adhesive has no significant tack prior to being activated, can be repositionable for at least 1 minute after activation, and can form a strong bond less than two hours after activation. Also provided are labels comprising the water-activated adhesive, methods for producing and using the water-activated adhesive, and systems for labeling articles with the water-activated adhesive. | 2020-12-24 |
20200399508 | VISCOELASTIC FOAM WITH SLOW RECOVERY TIME - Recovery times of flexible polyurethane foams are increased by treatment with a pressure sensitive adhesive. An emulsion or dispersion of the adhesive in an aqueous carrier liquid is impregnated into the foam, with subsequent removal of the carrier. This invention is of special interest when the glass transition temperature of the starting foam is 16° C. or lower. | 2020-12-24 |
20200399509 | SHOE INSOLE WITH AMBER - The utility model relates to the light industry and is intended for use as a prophylactic and hygienic means for human feet. A shoe insole with amber consists of a base and filler, wherein the base is made of an adhesive composition, in which the filler is located, and the filler is amber stones. The insole allows maintaining the prophylactic and hygienic effect during a long-term use thereof. | 2020-12-24 |
20200399510 | PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET - Provided is a PSA composition capable of achieving excellent moisture resistance. | 2020-12-24 |
20200399511 | NEW ADDITIVE TO IMPROVE ADHESIVE COMPOSITIONS - Disclosed are an additive composition for an adhesive composition as well as an adhesive composition itself that is based on starch, dextrin or polyvinyl alcohol as the adhesive component. The additive composition includes a cross-linked carbomer and a metasilicate of an alkali metal or an alkaline earth metal in a ratio between 0.50 and 5.00, and with the metasilicate being present in a concentration of at least 1.70% wt in the additive composition in the form of a dry powder mixture. Further disclosed are kits in parts as well as a method for the production of these products, as well as uses for these products. | 2020-12-24 |
20200399512 | ADHESIVE AND ITS PREPARATION AND APPLICATION - The present invention relates to an adhesive, a preparation method and application thereof, particularly the application for bonding glass fiber composites, and a bonded article obtained by using the adhesive. The adhesive comprises: a polyisocyanate having an isocyanate functionality of not less than 2; an epoxy-modified polyether polyol; a hydroxyl-containing acrylate; a redox catalyst; a silane coupling agent; optionally a polyol containing bisphenol A structure; and optionally a polymer polyol different from the epoxy-modified polyether polyol. The adhesive according to the present invention has the advantages of being insensitive to moisture, good bonding properties and a long pot life. | 2020-12-24 |
20200399513 | LATENT TWO-PART POLYURETHANE ADHESIVES - Two-component polyurethane adhesives include a polyol component and a polyisocyanate component. The polyol component includes a high functionality polyether polyol and precipitated calcium carbonate particles having a particle size of up to 200 nm. The adhesive has an excellent combination of a prolonged open time followed by curing to form a strong adhesive bond. | 2020-12-24 |
20200399514 | LAMINATION ADHESIVE COMPOSITIONS AND THEIR APPLICATIONS - Two part silicone lamination adhesive compositions which cure via a condensation cure chemistry using titanium and/or zirconium based catalysts at room temperature are disclosed. The compositions comprise: (i) at least one condensation curable silyl terminated polymer having at least one hydrolysable and/or hydroxyl functional group(s) per molecule; (ii) a cross-linker; and (iii) a condensation catalyst selected from the group of titanates and zirconates. Polymer (i) is not stored in the same part as cross-linker (ii) and catalyst (iii). Catalyst (iii) is present in a molar amount which is at least 50% of the moisture present cumulatively in the parts of the composition. The molar ratio of silicon bonded hydroxyl groups in polymer (i) to hydrolysable groups in cross-linker (ii) is above 0.15. The molar ratio of the silicon bonded hydroxyl groups in polymer (i) to M-OR functions is greater than 10, where M is titanium or zirconium. | 2020-12-24 |
20200399515 | AEROSOL COMPOSITIONS - The present application provides liquefied-gas aerosol compositions which are useful in for preventing incidents of inhalation abuse. The compositions described herein comprise, for example, i) a propellant component comprising one or more hydrohaloolefins; and ii) one or more bitterants. | 2020-12-24 |
20200399516 | COLD STORAGE MATERIAL COMPOSITION AND USE THEREOF - A cold storage material composition is provided allowing for temperature maintenance of a temperature control target article in various control temperature ranges in a range of −75° C. to −55° C. and being capable of solidifying within a given period of time and (ii) a technique of using the cold storage material composition. Also provided is a cold storage material composition including calcium ions, chloride ions, bromide ions, and ammonium ions in respectively specific amounts, relative to 100 mol of water, and having a melting temperature in a range of −75° C. to −55° C. | 2020-12-24 |
20200399517 | ENERGY EFFICIENT CEMENTITIOUS MORTARS - Thermally conductive cementitious compositions for use in flooring installations that are applied over a heat radiating flooring system to increase the thermal conductance of the flooring system and increase the rate of heating the flooring system. The thermally conductive cementitious compositions include a cementitious composition, amorphous flake graphite carbon, and an aqueous solution suitable for use as a thermally conductive mortar, grout or adhesive for flooring installations. The thermally conductive cementitious compositions also include a cementitious composition, mesh fine aluminum oxide, mesh coarse aluminum oxide, and an aqueous solution that provides a thermally conductive mortar, grout or adhesive for use in flooring installations. | 2020-12-24 |
20200399518 | ADDITIVES FOR OIL AND GAS DRILLING AND PRODUCTION - A quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of synthesizing a quaternary amine composition comprising the steps of reacting an alkoxylated dimer diamine with a methyl halogen, where the methyl halogen is selected from the group consisting of methyl chloride, methyl iodine, and combinations of the same; and allowing the reaction to proceed to produce the quaternary amine composition, the quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of treating a well comprising the steps of introducing an additive-containing well fluid to a well, where the additive-containing well fluid comprises a quaternary amine composition and a well fluid, allowing the additive-containing well fluid to interact with the well, and treating the well with the additive-containing fluid. | 2020-12-24 |
20200399519 | ADDITIVES FOR OIL AND GAS DRILLING AND PRODUCTION - A quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of synthesizing a quaternary amine composition comprising the steps of reacting an alkoxylated dimer diamine with a methyl halogen, where the methyl halogen is selected from the group consisting of methyl chloride, methyl iodine, and combinations of the same; and allowing the reaction to proceed to produce the quaternary amine composition, the quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of treating a well comprising the steps of introducing an additive-containing well fluid to a well, where the additive-containing well fluid comprises a quaternary amine composition and a well fluid, allowing the additive-containing well fluid to interact with the well, and treating the well with the additive-containing fluid. | 2020-12-24 |
20200399520 | ADDITIVES FOR OIL AND GAS DRILLING AND PRODUCTION - A quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of synthesizing a quaternary amine composition comprising the steps of reacting an alkoxylated dimer diamine with a methyl halogen, where the methyl halogen is selected from the group consisting of methyl chloride, methyl iodine, and combinations of the same; and allowing the reaction to proceed to produce the quaternary amine composition, the quaternary amine composition selected from the group consisting of Formula I, Formula II, Formula III, and combinations of the same. A method of treating a well comprising the steps of introducing an additive-containing well fluid to a well, where the additive-containing well fluid comprises a quaternary amine composition and a well fluid, allowing the additive-containing well fluid to interact with the well, and treating the well with the additive-containing fluid. | 2020-12-24 |
20200399521 | DRILLING FLUIDS THAT INCLUDE WATER-SOLUBLE ACID CATALYSTS AND USES FOR SUCH - In accordance with one or more embodiments of the present disclosure, a drilling fluid may include a base fluid, one or more formaldehyde-based resins, and one or more water-soluble acid catalysts. The base fluid may include an aqueous or non-aqueous solution. The one or more water-soluble acid catalysts may be present in an amount sufficient to reduce the pH of the drilling fluid to less than or equal to 6. The present disclosure also describes sealed subterranean petroleum formations that include such drilling fluids and methods for sealing subterranean wellbores by utilizing such drilling fluids. | 2020-12-24 |
20200399522 | DRILLING FLUIDS THAT INCLUDE WATER-SOLUBLE ACID CATALYST PRECURSORS OR REACTION PRODUCTS OF SUCH AND USES FOR SUCH DRILLING FLUIDS - In accordance with one or more embodiments of the present disclosure, a drilling fluid may include a base fluid and one or more formaldehyde-based resins. The drilling fluid may further comprise one or more water-soluble acid catalyst precursors or the reaction products of such water-soluble acid catalyst precursors. The base fluid may include an aqueous or non-aqueous solution. The present disclosure also describes sealed subterranean petroleum formations that include such drilling fluids and methods for sealing subterranean wellbores by utilizing such drilling fluids. | 2020-12-24 |
20200399523 | DRILLING FLUIDS THAT INCLUDE WATER-INSOLUBLE ACID CATALYST PRECURSORS OR REACTION PRODUCTS OF SUCH AND USES FOR SUCH DRILLING FLUIDS - In accordance with one or more embodiments of the present disclosure, a drilling fluid may include a base fluid and one or more formaldehyde-based resins. The drilling fluid may further comprise one or more water-insoluble acid catalyst precursors or the reaction products of such water-insoluble acid catalyst precursors. The present disclosure also describes sealed subterranean petroleum formations that include such drilling fluids and methods for sealing subterranean wellbores by utilizing such drilling fluids. | 2020-12-24 |
20200399524 | MITIGATING ANNULAR PRESSURE BUILDUP WITH NANOPOROUS METAL OXIDES - Methods and systems for mitigating annular pressure buildup in a wellbore are provided. An example method comprises introducing a treatment fluid into an annulus of the wellbore, wherein the annulus has an annular pressure, and wherein the treatment fluid comprises an aqueous base fluid and a nanoporous metal oxide. The method further comprises allowing or causing to allow at least a portion of the treatment fluid to remain in the annulus; and allowing or causing to allow the annular pressure to increase thereby inducing at least a portion of the aqueous base fluid to enter into an interior volume of the nanoporous metal oxide. | 2020-12-24 |
20200399525 | Well Cementing Method for Improving Well Cementing Quality by Controlling Hydration Heat of Cement Slurry - A well cementing method is described for improving cementing quality by controlling the hydration heat of cement slurry. By controlling the degree and/or rate of hydration heat release from cement slurry, the method improves the hydration heat release during formation of cement with curing of cement slurry, improves the binding quality between the cement and the interfaces, and in turn improves the cementing quality at the open hole section and/or the overlap section. The cementing method improves cementing quality of oil and gas wells and reduces the risk of annular pressure. | 2020-12-24 |
20200399526 | CO-CULTIVATION OF A MYXOBACTERIUM AND ACINETOBACTER FOR ENHANCED PRODUCTION OF EMULSAN - Methods are provided for enhanced production of one or more microbial biopolymers, the methods comprising co-cultivating | 2020-12-24 |
20200399527 | FORMULATIONS FOR ENHANCED OIL RECOVERY COMPRISING SULFONATES - Compositions suitable for enhanced oil recovery comprising
| 2020-12-24 |
20200399528 | STABILIZED FOAMS WITH TAILORED WATER CHEMISTRY FOR MOBILITY CONTROL IN GAS INJECTION PROCESSES - The application discloses foam compositions, methods to produce foam compositions, and methods to increase hydrocarbon production by displacing a hydrocarbon product with a foam composition. The foam composition includes an aqueous phase that typically includes an amphoteric surfactant and inorganic ions. | 2020-12-24 |
20200399529 | VISCOSIFYING FRICTION REDUCERS - A water-in-oil emulsion that includes an oil phase (O) and an aqueous phase (A) at an O/A ratio of from about 1:8 to about 10:1; wherein the water-in-oil emulsion includes the oil phase as a continuous phase that includes an inert hydrophobic liquid, at least one water-insoluble hydrophobic monomer, and at least one surfactant, and the aqueous phase as a dispersed phase of distinct particles in the oil phase that includes water and a water soluble polymer that includes: (i) at least one acrylamide monomer and (ii) at least one acrylic acid monomer; wherein the water soluble polymer is present in an amount from about 10 to about 35 weight percent of the water-in-oil emulsion. Also provided is water-in-oil emulsion that includes an oil phase (O) and an aqueous phase (A) at an O/A ratio of from about 1:8 to about 10:1; wherein the water-in-oil emulsion includes the oil phase as a continuous phase that includes an inert hydrophobic liquid and at least one surfactant, and the aqueous phase as a dispersed phase of distinct particles in the oil phase that includes water and a water soluble polymer that includes: (i) at least one acrylamide monomer, (ii) at least one acrylic acid monomer, and (iii) at least one water soluble hydrophobic monomer; wherein the water soluble polymer is present in an amount from 10 to 35 weight percent of the water-in-oil emulsion. Methods of treating a portion of a subterranean formation with a water-in-oil emulsion are also provided. | 2020-12-24 |
20200399530 | Aqueous Delayed Acid System for Well Stimulation - The disclosure relates to an aqueous acidizing fluid. In addition to an acid, the fluid contains an organophosphorus surfactant and/or an acid retarder. The organophosphorus surfactant may be an amino phosphonate or a phosphino carboxylate. The acid retarder comprises the combination of urea or a urea derivative and a bifunctional organic compound. Suitable bifunctional organic compounds contain at least one quaternary ammonium or phosphonium and at least one alcohol as well as salts of nitrogen containing heterocyclic rings. | 2020-12-24 |
20200399531 | Composition And Method For Improving Performance Of Friction Reducing Polymers In High Dissolved Solids Water - Systems and methods include using a fracture fluid downhole for fracturing a formation. The method includes providing an aqueous solution comprising dissolved solids at a certain ionic strength, and adding a proppant to create a fracture fluid. The method continues by adding a polymeric additive and a surfactant to the fracture fluid, wherein the polymeric additive comprises friction reducing capabilities that can be decreased by the ionic strength present in the fracture fluid (i.e., ionic strength originally found in the water). The addition of the polymeric additive and the surfactant to the fracture fluid creates an enhanced fracture fluid, wherein the surfactant increases the performance of the friction reducing capabilities of the polymeric additive in the enhanced fracture fluid, which provides a more efficient fracturing operation. The method concludes by pumping the enhanced fracture fluid downhole for a more efficient fracture of the formation. | 2020-12-24 |
20200399532 | SEMICONDUCTOR NANOCRYSTAL AND PREPARATION METHOD THEREOF - A semiconductor nanocrystal and a preparation method thereof, where the semiconductor nanocrystal include a bare semiconductor nanocrystal and a water molecule directly bound to the bare semiconductor nanocrystal. | 2020-12-24 |
20200399533 | ELECTROLUMINESECENT MATERIAL, METHOD FOR MANUFACTURING SAME, AND LIGHT EMITTING DEVICE - The present application provides an electroluminescent material, a method for manufacturing the electroluminescent material, and a light emitting device, the asymmetric monocyanopyrazine of the pyrene nucleus of the electroluminescent material is used as an acceptor, and the pyrene nucleus has a large plane and rigid P-type delayed fluorescence characteristic, which can combine triplet excitons via triplet excitons-triplet excitons to enhance utilization of excitons, thereby to achieve an electroluminescent material, a method for manufacturing the electroluminescent material, and a light emitting device, to realize an electroluminescent material and a light emitting device with a high quantum efficiency. | 2020-12-24 |
20200399534 | Photo-Activatable Aggregation-Induced Emission Probe with In-Situ Generation Capability, Preparation Method Therefor and Application Thereof - The present invention, belonging to the technical field of biological imaging, discloses a photo-activatable aggregation-induced emission probe with in-situ generation capability, a preparation method therefor and an application thereof. The preparation method is as follows: A bis(2-(2-hydroxybenzylidene)amino)aryl disulfide compound is reacted with thiol to obtain a photo-activatable aggregation-induced emission probe, which has a structure as shown in formula III. In the present invention, the photo-activatable aggregation-induced emission probe is aggregated into a specific organelle, and a 2-(2-hydroxyphenyl)benzothiazole compound having the aggregation-induced emission property is generated through a photo-oxidation reaction. The photo-activatable aggregation-induced emission probe generated in situ of the present invention can effectively overcome the defects of aggregation-induced quenching of traditional fluorescent dyes, and realize organelle-targeted specific photo-activatable fluorescence imaging in living cells, having such advantages as easy preparation, long-term storage, high photo-activation efficiency, large Stokes shift, and strong ability to enter cells. | 2020-12-24 |
20200399535 | BRIGHT SILVER BASED QUATERNARY NANOSTRUCTURES - Disclosed are nanostructures comprising Ag, In, Ga, and S and a shell comprising Ag, Ga and S, wherein the nanostructures have a peak wavelength emission of 480-545 nm and wherein at least about 80% of the emission is band-edge emission. Also disclosed are methods of making the nanostructures. | 2020-12-24 |
20200399536 | QUANTUM DOTS, A COMPOSITION OR COMPOSITE INCLUDING THE SAME, AND AN ELECTRONIC DEVICE INCLUDING THE SAME - A quantum dot, and a composite and a display device including the quantum dot. The quantum dot comprises a semiconductor nanocrystal core comprising indium and phosphorous, a semiconductor nanocrystal shell disposed on the semiconductor nanocrystal core, the first semiconductor nanocrystal shell comprising zinc, selenium, and sulfur, wherein the quantum dot does not comprise cadmium wherein the quantum dot has a maximum photoluminescence peak in a green light wavelength region, and wherein in an ultraviolet-visible (UV-Vis) absorption spectrum of the quantum dot, a ratio A | 2020-12-24 |
20200399537 | Liquid Crystal for Longwave Infrared Applications - Liquid crystal molecules are described with desirably reduced attenuation in portions of the long-wave infrared (LWIR) spectrum. The molecules include a linear hydrocarbon of varying length (C | 2020-12-24 |
20200399538 | OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY DEVICE - An object of the present invention is to provide an optical film which is excellent in the adhesiveness between a polymer support and a photo alignment film and in which a liquid crystal compound having reverse wavelength dispersibility is uniformly aligned. Another object of the present invention is to provide a polarizing plate formed of the optical film, and an image display device formed of the optical film or the polarizing plate. | 2020-12-24 |
20200399539 | POLYMERIZABLE COMPOUND AS WELL AS LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE EACH INCLUDING POLYMERIZABLE COMPOUND - The present invention provides a compound represented by the general formula (i), which has a partial structure K | 2020-12-24 |
20200399540 | BROMINATED FLAME-RETARDANT TETRAZINES - A flame-retardant compound, a process for forming a flame-retardant compound, and an article of manufacture. The flame-retardant compound includes a tetrazine moiety and at least one ligand comprising a brominated moiety. The process includes providing starting materials, which include a nitrile compound, a bromine source, and hydrazine. The process also includes reacting the starting materials to form a tetrazine flame retardant. The article of manufacture includes a polymer and a flame-retardant compound having a tetrazine moiety and at least one ligand comprising a brominated moiety. | 2020-12-24 |
20200399541 | Microwave-Based Recovery Of Hydrocarbons And Fossil Fuels - The present invention provides methods for decomposing and extracting compositions for the recovery of petroleum-based materials from composites comprising those petroleum-based materials, comprising subjecting the compositions and/or composites to microwave radiation, wherein the microwave radiation is in the range of from about 4 GHz to about 18 GHz. The present invention also provides for products produced by the methods of the present invention and for apparatuses used to perform the methods of the present invention. | 2020-12-24 |
20200399542 | Fischer-Tropsch Process, Supported Fischer-Tropsch Synthesis Catalyst and Uses Thereof - A process for converting a mixture of hydrogen and carbon monoxide gases to a composition comprising alcohols and liquid hydrocarbons by means of a Fischer-Tropsch synthesis reaction, said process comprising contacting a mixture of hydrogen and carbon monoxide gases, preferably in the form of synthesis gas mixture, with a supported Co—Mn Fischer-Tropsch synthesis catalyst, wherein: the support material of the supported Co—Mn Fischer-Tropsch synthesis catalyst comprises a material selected from titania, zinc oxide, zirconia, and ceria; the supported synthesis catalyst comprises at least 2.5 wt % of manganese, on an elemental basis, based on the total weight of the supported synthesis catalyst; the weight ratio of manganese to cobalt, on an elemental basis, is 0.2 or greater; the molar ratio of hydrogen to carbon monoxide is at least 1; and, the Fischer-Tropsch synthesis reaction is conducted at a pressure in the range of from 1.0 to 10.0 MPa absolute. | 2020-12-24 |
20200399543 | METHODS FOR METHANOL-TO-GASOLINE CONVERSION WITH METHANOL RECYCLING - Methanol-to-gasoline (MTG) conversion may be performed with a methanol recycling. Methanol may be fed to a first reactor where it may be catalytically converted under dimethyl ether formation conditions in the presence of a first catalyst to form a product mixture comprising dimethyl ether (DME), methanol, and water. The DME may be separated from the methanol and the water and delivered to a second reactor. In the second reactor, the DME may be catalytically converted under MTG conversion conditions in the presence of a second catalyst to form a second product mixture comprising gasoline hydrocarbons and light hydrocarbon gas. The methanol and the water from the first reactor may be separated further to obtain substantially water-free methanol, which may be returned to the first reactor. The separation of methanol from the water may be performed using the light hydrocarbon gas to effect stripping of the methanol. | 2020-12-24 |
20200399544 | METHODS FOR METHANOL-TO-GASOLINE CONVERSION WITH FORWARDING METHANOL PROCESSING - Methanol-to-gasoline (MTG) conversion may be performed with forward methanol processing. Methanol may be fed to a first reactor where it may be catalytically converted under dimethyl ether formation conditions in the presence of a first catalyst to form a product mixture comprising dimethyl ether (DME), methanol, and water. The DME may be separated from the methanol and the water and delivered to a second reactor. In the second reactor, the DME may be catalytically converted under MTG conversion conditions in the presence of a second catalyst to form a second product mixture comprising gasoline hydrocarbons and light hydrocarbon gas. The methanol and the water from the first reactor may be separated further to obtain substantially water-free methanol, which may be delivered to the second reactor. The separation of methanol from the water may be performed using the light hydrocarbon gas to effect stripping of the methanol. | 2020-12-24 |
20200399545 | METHOD AND DEVICE FOR TREATMENT OF LIQUID HYDROCARBONS - Disclosed is a method and a device for purification and desulfurization of liquid hydrocarbons, which, compared to sodium dispersion desulfurizing processes like already been disclosed, open up additional fields of application and greatly improves economy and achievable results. | 2020-12-24 |
20200399546 | METHODS AND SYSTEMS FOR PRODUCING LIGHT OLEFINS FROM NAPHTHA - Methods and systems for producing olefins from a naphtha feedstock are provided. Methods can include pyrolyzing the naphtha feedstock in the presence of hydrogen gas to produce a first effluent, separating the first effluent into light components, heavy components and one or more olefin product streams, steam cracking the light components to produce a second effluent, and extracting aromatics, if any, from the heavy components to produce a third effluent. | 2020-12-24 |
20200399547 | Integrated Desolidification for Solid-Containing Residues - A desolidification process enables the isolation and extraction of solid additives from an unreacted petroleum residue stream. In a hydrocracking process that mixes a solid additive with a petroleum residue feedstock to convert the petroleum residue to higher-value distillates, the desolidification process enables the recovery of the unreacted petroleum residue for conversion to a saleable product. The desolidification process involves the mixture of one or more solvents with a slurry in which solids are integrated in the petroleum residue to generate a mixture having a decreased density and viscosity as compared to the slurry, which facilitates removal of the solids. | 2020-12-24 |
20200399548 | GAS PURIFICATION DEVICE - A gas purification device removes a part of ammonia contained in a first gas; recovers a first off-gas containing the removed ammonia, removes hydrogen sulfide and ammonia from a second gas produced by removing the part of ammonia, recovers a second off-gas containing the removed hydrogen sulfide and ammonia, and combusts the first off-gas and the second off-gas. The gas purification device includes: a first combustion chamber in which combustion is performed in a reducing atmosphere; a second combustion chamber in which combustion is performed in a reducing atmosphere downstream of the first combustion chamber; and a third combustion chamber in which combustion is performed in an oxidizing atmosphere downstream of the second combustion chamber. The first off-gas flows into the first combustion chamber and the second off-gas flows into the third combustion chamber. | 2020-12-24 |
20200399549 | A BIOFUEL COMPOSITION COMPRISING LIGNIN - A biofuel composition and a process for the manufacture of a biofuel composition including lignin and ethanol as the main combustible components of the biofuel composition and having total ash below 1% w/w based on total mass of dry matter in the biofuel composition. | 2020-12-24 |
20200399550 | FUEL - An improved fuel, particularly an improved transport fuel composition is provided. Alternate fuels to traditional oil derived petrol and diesel have been considered particularly for transport purposes. However, there are limitations that have prevented their widespread use. A fuel composition is provided for use in an internal combustion engine comprising an organic carrier fuel having a particulate additive dispersed therein, the particulate additive being a lubricant. | 2020-12-24 |
20200399551 | METHODS OF IGNITING A FUEL SOURCE, LIGHTER FLUID COMPOSITIONS AND SELF-LIGHTING CHARCOAL BRIQUETTES - The present application provides charcoal briquettes infused with a flammable composition including fusel oil and/or one or more dehydration products of fusel oil and the flammable compositions including one or more dehydration products of fusel oil. | 2020-12-24 |
20200399552 | Glycol Ether Neo-Esters, Lubricating Oil Compositions Containing Same And Processes For Making Same - Compositions include ether ester compounds derived from neo-acids, lubricating oil base stocks containing such ester compounds, and lubricating oil compositions containing such ester compounds. Methods can include making and formulating compositions containing ether ester compounds derived from neo-acids. | 2020-12-24 |
20200399553 | Glycol Ether Ester Compounds Of Neo-Alcohols Useful In Lubricating Oil Compositions And Methods Of Making The Same - Compositions include ether ester compounds derived from neo-alcohols, lubricating oil base stocks containing such ester compounds, and lubricating oil compositions containing such ester compounds. Methods can include making and formulating compositions containing ether ester compounds derived from neo-alcohols. | 2020-12-24 |
20200399554 | Novel Grease and Methods of Making the Same - The present disclosure relates to a high performance calcium sulfonate greases with enhanced performance benefits and methods for making the same. | 2020-12-24 |
20200399555 | LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINE - The invention is directed to a method for reducing low speed pre-ignition events in a spark-ignited direct injection internal combustion engine by supplying to the sump a lubricant composition which contains an oil of lubricating viscosity and an ashless dispersant. The ashless dispersant may be selected from succinimide compounds prepared from aliphatic or aromatic amines. | 2020-12-24 |
20200399556 | LUBRICANT COMPOSITIONS FOR DIRECT INJECTION ENGINE - The invention is directed to a method for reducing low speed pre-ignition events in a spark-ignited direct injection internal combustion engine by supplying to the sump a lubricant composition which contains an oil of lubricating viscosity and an ashless dispersant. The ashless dispersant may be selected from succinimide compounds prepared from aliphatic or aromatic amines. | 2020-12-24 |
20200399557 | OIL PROCESSING - A process for the production of a refined oil having a reduced content of glycidyl esters and hydroperoxides characterized in that it comprises subjecting an edible oil to the following steps, a bleaching step, a deodorization step, re-bleaching step on the deodorized oil, and a further refining step, wherein the further refining step is carried out by passing the bleached edible oil obtained in step c) through an oil refining equipment consisting of a stripping column with packing and not more than one oil collection tray. | 2020-12-24 |
20200399558 | METHODS FOR IDENTIFYING, COMPOUNDS IDENTIFIED AND COMPOSITIONS THEREOF - Provided herein are screening methods for identifying one or more compounds that impart a smell, taste and/or trigeminal sensation, for example, odorants contributing to an olfactory quality. Further provided are one or more compounds identified using the screening methods described herein, and compositions containing such compounds. | 2020-12-24 |
20200399559 | POLYMERIC COMPOSITE PARTICLES - Compositions are provided that include a matrix and a polymeric composite particles disposed in the matrix. The polymeric composite particles include a porous polymeric core and a fragrance positioned within the porous polymeric core. Polymeric composite particles are also provided including a porous polymeric core, a fragrance positioned within the porous polymeric core, and a coating layer around the porous polymeric core. Further, a method of determining a minimum temperature of a composition is provided including providing a composition including polymeric composite particles disposed in a matrix, heating the composition, releasing at least a portion of the fragrance as a vapor from the porous polymeric core of the polymeric composite particles at or above the minimum temperature, and detecting at least a portion of the fragrance vapor in a location outside of the matrix. | 2020-12-24 |
20200399560 | ODOROUS ACETALS OF ETHYL VANILLIN AND ETHYL VANILLIN DERIVATIVES - The present invention relates to new odorous acetals which are useful as fragrance or flavor materials in particular in providing vanilla and spicy notes with a natural impression resembling vanilla absolute. | 2020-12-24 |
20200399561 | REDUCTION OF SURFACE TENSION, INTERFACIAL TENSION, AND CRITICAL MI CELLE CONCENTRATION USING A PROTEIN-BASED SURF ACT ANT SYNERGIST - Surfactant-containing compositions are described which include a protein component that has the effect of improving the surface-active properties of the surfactants contained in the compositions. The surfactant-containing compositions having the protein component demonstrate significantly lower critical micelle concentrations (CMC), reduced surface tensions, and reduced interfacial tensions than do comparable compositions having no protein component. In addition, the surfactant-containing compositions having the protein component has the effect of converting greasy waste contaminants to surface active materials. | 2020-12-24 |
20200399562 | METHOD OF TREATING A FABRIC - A method of treating a fabric, comprising contacting the fabric with an aqueous liquor comprising a fabric care component selected from the group consisting of cationic softening-compounds, silicone softening-compounds, paraffins, dispersible polyolefins, waxes and mixtures thereof; and contacting the fabric with an aqueous liquor comprising a nuclease enzyme, preferably a deoxyribonuclease or ribonuclease enzyme. The aqueous liquor may be provided by adding a cleaning or treatment composition to water. Preferably the composition comprises a surfactant, the wash liquor comprising from 0.05 to 4 g/l of a surfactant. | 2020-12-24 |
20200399563 | SOLIDIFYING NONIONIC SURFACTANTS - The invention relates to solidification of liquid nonionic surfactants with a binder, carrier, or both binder and carrier to form a solidified surfactant composition. In particular, the invention relates to solidification of liquid nonionic surfactants utilizing drying device(s), wherein the feed composition contains at least one liquid nonionic surfactant and the binder, carrier, or binder and carrier to form a solidified surfactant composition. The solidified surfactant compositions can be useful in various cleaning compositions. | 2020-12-24 |
20200399564 | Polymers For The Treatment Of Surfaces - Catechol-group-containing polymers with amine or amide functionality, containing at least one repeating unit of the formula (I) and at least one repeating unit of the formula (II) and optionally further repeating units | 2020-12-24 |
20200399565 | NON-AQUEOUS TUNGSTEN COMPATIBLE METAL NITRIDE SELECTIVE ETCHANTS AND CLEANERS - Provided therefore herein is a novel acidic fluoride activated cleaning chemistry. The present invention includes novel acidic fluoride activated, unique organic-solvent based microelectronic selective etchant/cleaner compositions with high metal nitride etch and broad excellent compatibility, including tungsten (W) and low-k. It does not use W-incompatible oxidizers, such as hydrogen peroxide or particle-generating corrosion inhibitors. | 2020-12-24 |
20200399566 | POTASSIUM SOAPS THAT CAN BE THICKENED WITH CHLORIDE SALTS - Natural liquid potassium soap compositions and methods of manufacturing and using the same are provided with thickening by the addition of chloride salts, such as sodium chloride and potassium chloride. The natural liquid potassium soap compositions may contain one or more fatty acids with carbon length ranging from four (C4) to twenty-two (C22) or natural fatty acid mixtures with coconut oil, olive oil, tallow, sunflower oil, safflower oil, and/or tall oil fatty acids which are saponified with lye. The saponification lye is preferably potassium hydroxide. Preferred embodiments contain potassium salts of fatty acids comprising at least oleic acid (C18:1 cis-9), olive oils, coconut oils or mixtures thereof. The chloride salt is added in either solid or liquid form following saponification and neutralization. | 2020-12-24 |
20200399567 | LOW ALKALINE LOW TEMPERATURE WARE WASH DETERGENT FOR PROTEIN REMOVAL AND REDUCING SCALE BUILD-UP - Caustic-free detergent compositions are provided. Detergent compositions including an aminocarboxylate, water conditioning agent, non-caustic source of alkalinity and water beneficially do not require the use of additional surfactants and/or polymers to provide suitable detergency and prevent scale build-up on treated surfaces and enhance protein removal from the treated surfaces. Beneficially the detergent compositions have a concentrate pH less than about 11.5. The detergent compositions are used with a sanitizer to employ the low alkaline detergent compositions are particularly suitable for use as low temperature ware wash detergents that beneficially reduce scale build-up. Methods of employing the low alkaline detergent compositions are also provided. | 2020-12-24 |
20200399568 | Washing- And Cleaning-Active Polymer Films, Process For Their Production And Their Use - The present disclosure relates to a washing- and cleaning-active polymer film which includes a mixture of at least one polymer P1) including polymerized units of at least one α,β-ethylenically unsaturated carboxylic acid or a salt thereof. The washing- and cleaning-active polymer film optionally further includes comonomers and a polyoxyalkylene ether PE). The disclosure furthermore relates to a process for producing such a washing- and cleaning-active polymer film and to a covering or coating for a detergent or cleaner portion which includes such a polymer film. | 2020-12-24 |
20200399569 | BEVERAGE FILTRATION DEVICE - A device including a lid body including a connection end, a top end having an opening therein, a pouring spout body encompassing the opening, and, a stem body including an internal housing configured to hold an ion exchange resin-filed cartridge therein, a cap region, collar, a beverage conduit, and a stem body air tube. The cap region configured to couple to the connection end of the lid body to thereby form a first liquid-tight seal coupling between the connection end of the lid body and a top end of the ion exchange resin-filed cartridge, and, form a second a liquid-tight seal coupling between a base region of the internal housing and a bottom end of the ion exchange resin-filed cartridge. First and second collar wall portions sized to fit inside a mouth of a beverage container and to be located outside of the mouth. The beverage conduit spans the collar with a first and second openings to the base region and an interior of the beverage container. The stem body air tube extends through the collar with proximal and distal openings to an air vent hole located in the second portion of the collar wall and to the interior of the beverage container. | 2020-12-24 |
20200399570 | METHODS OF SEPARATING FILAMENTOUS FUNGI AND OTHER COMPONENTS FROM MOLD-FERMENTED COMPOSITIONS, AND USES OF SEPARATED COMPONENTS - Methods of separating components traditionally considered as waste material from mold-fermented compositions are described. The waste components can be separated either from unfiltered compositions or from a separation stream separated from a composition. In some embodiments, filamentous fungus used in the production of the mold-fermented composition is specifically targeted for separation. Incorporation of separated waste components into various products are also described herein. In some embodiments, the separated components are used in alternative meat products and other foods designed for human consumption. Separated components can also be used in animal feed, as feed stock for other fermentation processes, or for use in treating food, creating cosmetics, or chemical processes. | 2020-12-24 |
20200399571 | CELL CULTURING DEVICE AND METHOD - A cell culturing device and method of using same are provided. Embodiments of the cell culturing device include a plate having at least one well with a through-hole formed at a bottom wall thereof and a hydrogel matrix disposed in the through hole. The cell culturing device can also include an optically transparent plate at the bottom of the through-hole. | 2020-12-24 |
20200399572 | DISPOSABLE CELL CULTURE BAG - Disclosed is a disposable cell culture bag capable of facilitating cell culture by using a flexible transparent resin film, the disposable cell culture bag including a body having a sealed space for accommodating a medium, and made of a flexible transparent resin film usable for disposable products, and one or more tubing lines extending from an inside to an outside of the body, wherein the body includes a bottom-side integrated part provided by extending one or more side surfaces from a bottom surface of the body to be spread in a radial shape, in order to obtain continuously smooth four edges of the bottom surface, and a top surface fusion bonded to the side surfaces of the bottom-side integrated part after the side surfaces are fusion bonded to each other. | 2020-12-24 |
20200399573 | MICROFLUIDIC CELL CULTURE OF PATIENT-DERIVED TUMOR CELL SPHEROIDS - Provided herein are methods for culturing patient-derived tumor cell spheroids in a three-dimensional microfluidic device. The method comprises mincing primary tumor sample in a medium supplemented with serum; treating the minced primary tumor sample with a composition comprising an enzyme; collecting tumor spheroids having a diameter of 10 μm to 500 μm from the enzyme treated sample; suspending the tumor spheroids in biocompatible gel; and culturing the tumor spheroids in a three dimensional microfluidic device. Methods for identifying an agent for treating cancer and microfluidic devices that allow for the simultaneous exposure of the cultured patient-derived primary tumor cell spheroids to a treatment of choice and to control treatment are also provided. | 2020-12-24 |
20200399574 | WATER-RECONSTITUTABLE CULTURE MEDIUM RESISTANT TO LIQUEFACTION BY MICROORGANISMS - A device for growing microorganisms is provided. The device includes a body member comprising a self-supporting, waterproof substrate, a layer of adhesive disposed on the substrate, a powder adhered to the adhesive, a cover sheet adhered to the body member, and a dry composition including a mixture of hydroxypropylmethylcellulose and guar gum adhered to the cover sheet or the substrate. The powder comprises a cold-water-soluble gelling agent and one or more nutrient for growing microorganisms. The composition, when reconstituted with water, resists liquefaction by microorganisms A method of culturing microorganisms using the device is also provided. | 2020-12-24 |
20200399575 | BIOCOMPATIBLE COMPOSITE ELEMENTS AND METHODS FOR PRODUCING - A biocompatible composite element for a bioreactor is provided that includes an outer frame and an inner component. The outer frame is a polymeric material. The outer frame can be inseparably attached to a wall of the bioreactor. The inner component is a transparent material selected from a group consisting of glass, sapphire, and glass ceramic. The inner component is secured in the outer component in an inseparable hermetically tight manner. The inner component is configured for a spectral process control through the transparent material of the inner component. | 2020-12-24 |
20200399576 | SCAFFOLDING MATERIAL FOR CELL CULTURES AND CELL CULTURE METHOD USING SAME - A scaffolding material for culturing a cell, the scaffolding material for culturing a cell containing a synthetic resin, and having a nitrogen content of the synthetic resin of 0.1% by mass or more and 10% by mass or less. According to the scaffolding material for cell culture, the scaffolding material can have suitable hydrophilicity and strength, high fixation of cells after seeding, and highly efficient cell proliferation. | 2020-12-24 |
20200399577 | SAMPLING DEVICE AND COMBINATION OF SAMPLING DEVICE AND SAMPLE VESSEL - This invention relates to a sampling device comprising a shaft and a sample collection portion removably connected with the shaft, wherein the connection site between the shaft and the sample collection portion is weakened. The invention relates also to a combination of a sampling device comprising a shaft and a removable sample collection portion and a sample vessel configured to receive sample collection portion from the shaft. | 2020-12-24 |
20200399578 | Devices, Methods, and Systems for Electroporation - Disclosed are a system, device, and method for the electroporation of cells. Systems, devices and methods for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where living cells and biologically active molecules flow through a channel that exposes them to electric fields, causing the molecules to be transferred across the cell membrane. The methods are particularly well suited for the introduction of DNA, RNA, drug compounds, and other biologically active molecules into living cells for use in cell-based therapies. | 2020-12-24 |
20200399579 | FLOW THROUGH ELECTROPORATION MODULES AND INSTRUMENTATION - The present disclosure provides a flow-through electroporation device configured for use in an automated multi-module cell processing environment and configured to decrease cell processing time and the risk of clogging. | 2020-12-24 |
20200399580 | SYSTEMS, APPARATUS AND METHODS FOR CONTROLLING A MOVEMENT OF A CELL CULTURE TO OPTIMIZE CELL GROWTH - A system for controlling a motion of a cell culture includes a tray adapted to hold a cell culture, a camera adapted to capture an image of the cell culture, and a device adapted to control a movement of the tray. The system also includes a processor adapted to determine a first movement of the tray, receive from the camera data representing an image of the cell culture, determine a characteristic of the cell culture based on the image data, determine a second movement of the tray based on the characteristic, the second movement being different from the first movement, and cause the tray to move in accordance with the second movement. | 2020-12-24 |
20200399581 | TEST DEVICE - The invention provides a technology for promptly determining bacterial identification or an antimicrobial susceptibility testing. In the invention, first, a state where the bacteria are divided is monitored by performing microscopic observation with respect to the shape or the number of bacteria in each of wells of a culture plate for bacterial identification culture or the antimicrobial susceptibility testing. In addition, the shape, the number or the area of the bacteria are interpreted from the image obtained by the microscopic observation whether or not the bacteria proliferate at a stage from an induction phase to a logarithmic phase, and the time-dependent changes thereof are made into a graph. From the graph, it is determined whether or not the bacteria proliferate for each measurement, the determination results are displayed on the screen, and accordingly, the result of the antimicrobial susceptibility is provided every time when the measurement is performed. | 2020-12-24 |
20200399582 | System and Method for Enabling a Single Use Wireless Sensor by Optimizing Electrical Power - A system for enabling a wireless single use sensing sub-system by optimizing electrical power is presented. The system includes the sensing sub-system configured to be employed in a bio process environment. Further, the sensing sub-system includes a sensing unit configured to measure at least one parameter of the bio process environment. Also, the sensing sub-system includes a power source electrically coupled to the sensing unit and configured to transmit an electrical power to the sensing unit. Furthermore, the sensing sub-system includes a switch configured to electrically couple or decouple the sensing unit from the power source. In addition, the system includes a control sub-system including a first controller configured to determine at least one power control parameter based on a user-input data and a sensing sub-system data, and optimize consumption of the electrical power in the sensing sub-system, based on the power control parameter. | 2020-12-24 |
20200399583 | ACOUSTIC PERFUSION DEVICES - Methods are disclosed for separating beads and cells from a host fluid. The method includes flowing a mixture containing the host fluid, the beads, and the cells through an acoustophoretic device having an ultrasonic transducer including a piezoelectric material driven by a drive signal to create a multi-dimensional acoustic standing wave. A drive signal is sent to drive the at least one ultrasonic transducer to create the multi-dimensional acoustic standing wave. A recirculating fluid stream having a tangential flow path is located substantially tangential to the standing wave and separated therefrom by an interface region. A portion of the cells pass through the standing wave, and the beads are held back from the standing wave in the recirculating fluid stream at the interface region. Also disclosed is an acoustophoretic device having a coolant inlet adapted to permit the ingress of a cooling fluid into the device for cooling the transducer. | 2020-12-24 |
20200399584 | INSTRUMENTS, MODULES, AND METHODS FOR IMPROVED DETECTION OF EDITED SEQUENCES IN LIVE CELLS - The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited. | 2020-12-24 |
20200399585 | PRODUCT PRODUCTION METHOD - Provided is a product production method which includes: a step of culturing a cell which produces a product and is contained in a cell suspension accommodated in a culture vessel; a separation treatment step of extracting the cell suspension from the culture vessel and separating the cell suspension by a tangential filtration method using a separation membrane; a step of returning a return liquid to the culture vessel; a step of supplying a fresh medium into the culture vessel; and a step of collecting the product, and in which with respect to a live cell concentration Nc, a pore diameter Dp of the separation membrane, a filtration area S of the separation membrane, and a volume Vf of a primary side flow path of the separation membrane, a number density Nd of fine particles having a particle size of 8 Dp to 30 Dp other than live cells in the cell suspension satisfies Nc≤Nd≤S/(32×π×Vf×Dp | 2020-12-24 |
20200399586 | GENOME-WIDE RATIONALLY-DESIGNED MUTATIONS LEADING TO ENHANCED LYSINE PRODUCTION IN E. COLI - The present disclosure relates to various different types of variants in | 2020-12-24 |
20200399587 | CULTURE MEDIUM FOR IMPROVING DEVELOPMENT OF BOVINE IN VITRO FERTILIZED EMBRYOS AND CLONED EMBRYOS - A culture medium for improving the development of bovine in vitro fertilized embryos and cloned embryos includes a SOF basal medium, progesterone, vitamin E, L-carnitine, FGF, corticosterone, citrulline, EGF, IGF and LIF. | 2020-12-24 |
20200399588 | WNT COMPOSITIONS AND METHODS OF PROCESS FROM SERUM-FREE CULTURING CONDITIONS - Disclosed herein are methods and compositions for producing a Wnt polypeptide under a serum-free condition. Also disclosed herein are methods of purifying the Wnt polypeptide from a serum-free condition. | 2020-12-24 |
20200399589 | MACROTUMOR ENGINEERING - A collagen-fibronectin-based method enables the production of tumors of centimeter size with recognizable pathological traits. The method supports reproducing tumor heterogeneity with preinvasive and invasive phenotypes and stacking of tumor portions using a paper-scaffold with 80 μm-punched holes for larger nodule creation and easy separation of tumor portions for analysis. Macrotumors are convenient for testing drug delivery and therapeutic tools that necessitate a minimum tumor size relevant to in vivo. | 2020-12-24 |
20200399590 | METHODS FOR FORMING THREE-DIMENSIONAL HUMAN RETINAL TISSUE IN VITRO - The present invention relates to the field of stem cells. More specifically, the invention provides methods and compositions useful for forming three-dimensional human retinal tissue in vitro. In a specific embodiment, an in vitro method for differentiating hiPSCs into three-dimensional retinal tissue comprising functional photoreceptors comprises the steps of (a) culturing the hiPSCs to form aggregates; (b) transitioning the aggregates into a neural induction medium; (c) seeding the aggregates on to extracellular matrix coated cell culture substrates; (d) replacing NIM with a chemically-defined differentiation medium; (e) detaching NR domains; (f) culturing in suspension; and (g) adding animal serum or plasma component and retinoic acid. | 2020-12-24 |
20200399591 | Protein engineered extracellular vesicles - The present invention relates to extracellular vesicles (EVs) as a novel therapeutic approach to lysosomal storage disorders (LSD). More specifically, the invention relates to the use of various protein engineering strategies for improving loading of hard-to-load LSD-related proteins and targeting of the resultant EVs to tissues and organs of interest. | 2020-12-24 |
20200399592 | SUSPENSION CULTURE OF HUMAN EMBRYONIC STEM CELLS - This disclosure provides an improved system for culturing human embryonic stem cells. The cells are cultured in suspension so as to maximize the production capacity of the culture environment. The new culture system of this invention allows for bulk proliferation of hES cells in a more cost-effective manner, which facilitates commercial production of important products for use in human therapy. | 2020-12-24 |
20200399594 | MORPHOGENIC COMPOUND-RELEASING MICROSPHERES AND USE IN BIOINK - The bioink disclosed herein includes one or more cells, a carrier material, and microspheres. The microspheres can include one or more biodegradable polymers and one or more compounds, such as a morphogenic compound. The methods disclosed herein can include three-dimensional bioprinting. Additional methods disclosed herein include producing functional tissue. | 2020-12-24 |
20200399595 | FUNCTIONAL OLIGODENDROCYTES DERIVED FROM PLURIPOTENT STEM CELLS AND METHODS OF MAKING AND USING THE SAME - Described is the efficient and robust generation of oligodendrocyte progenitor cells (OPCs) and oligodendrocytes from pluripotent stem cells (PSCs). The protocols provided recapitulate the major steps of oligodendrocyte differentiation, from neural stem cells to OLIG2 | 2020-12-24 |
20200399596 | B-CELL CULTIVATION METHOD - Herein is reported a method for the co-cultivation of single deposited B-cells, which can be of any source, with EL-4 B5 feeder cells in a suitable co-cultivation medium. In the herein reported methods the EL-4 B5 cells have been irradiated with a dose of less than 40 Gy, preferably 9.5 Gy or less. Thereby the EL-4 B5 cells have a higher viability and maintain the ability to divide in cultivation at doses less than 6 Gy. | 2020-12-24 |
20200399597 | T-CELL RECEPTOR-DEFICIENT T CELL COMPOSITIONS - The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. | 2020-12-24 |