51st week of 2017 patent applcation highlights part 37 |
Patent application number | Title | Published |
20170363546 | Gemstone Registration and Recovery System, and Systems for Evaluating the Light Performance of a Gemstone and Capturing Forensic Characteristics of a Gemstone - A computer-implemented system is provided and includes a processor and a memory accessible by the processor, with the system being configured to measure light performance properties of a gemstone and generate an objective grade for the gemstone. | 2017-12-21 |
20170363547 | DEFECT DETECTION METHOD AND DEFECT DETECTION DEVICE AND DEFECT OBSERVATION DEVICE PROVIDED WITH SAME - The disclosed device, which, using an electron microscope or the like, minutely observes defects detected by an optical appearance-inspecting device or an optical defect-inspecting device, can reliably insert a defect to be observed into the field of an electron microscope or the like, and can be a device of smaller scale. The electron microscope, which observes defects detected by an optical appearance-inspecting device or an optical defect-inspecting device, has a configuration incorporating an optimal microscope that re-detects defects, and a spatial filter and a distribution polarization element are inserted at the pupil plane when making dark-field observations using this optical microscope. The electron microscope, which observes defects detected by an optical appearance-inspecting device or an optical defect-inspecting device, has a configuration incorporating an optimal microscope that re-detects defects, and a distribution filter is inserted at the pupil plane when making dark-field observations using this optical microscope. | 2017-12-21 |
20170363548 | METHOD AND APPARATUS OF INSPECTING A SUBSTRATE WITH A COMPONENT MOUNTED THEREON - A method and an apparatus of inspecting a substrate with a component mounted thereon, which are capable of inspecting whether the component is properly mounted or not without additional setting or changing inspection condition, are provided. The method comprises measuring a three-dimensional shape by irradiating the pattern image toward the substrate through at least one illumination unit and by taking a reflected image through an imaging unit, extracting a shield region from the three-dimensional shape, and inspecting a component mounting defect in an area excluding the shield region in the three-dimensional shape. | 2017-12-21 |
20170363549 | METHODS AND APPARATUS FOR SEMICONDUCTOR SAMPLE WORKFLOW - Apparatus and methods are described for the automated transfer and storage of transmission electron microscope (TEM) and scanning/transmission electron microscope (STEM) lamella samples throughout a semiconductor manufacturing facility using existing automation infrastructure such as a Front Opening Unified Pod (FOUP). Also provided are wafer facsimiles corresponding to outer dimensions of semiconductor, data storage or solar cell wafers, wherein the facsimiles adapted to store, carry and/or provide a testing platform for testing of samples taken from semiconductor, data storage or solar cell wafers. | 2017-12-21 |
20170363550 | X-RAY DIFFRACTOMETER - An X-ray diffractometer for obtaining X-ray diffraction angles of diffracted X-rays by detecting with an X-ray detector diffracted X-rays diffracted at a sample when X-rays are emitted at the sample at each angle of the angles about a center point of goniometer circles, the X-ray diffractometer having a pinhole member provided with a pinhole, the pinhole allowing X-rays diffracted from the sample to pass so that the diffracted X-rays pass through the center point of the goniometer circle, and other diffracted X-rays are shielded by the pinhole member. | 2017-12-21 |
20170363551 | SYSTEM AND METHOD FOR DETERMINING TURF PERFORMANCE INDICATORS - System and method for quantifying qualitative turf conditions as they relate to turf performance and health. In an embodiment, data is collected about turf condition using a turf analysis device. The data collected aboute the conditions may be used to generate condition-based turf stress indexes that may be used to genasrte an overall a Turf Performance Indicator (TPI). Such collections are calculated through a unique quantitative mathematical equation resulting in a measurable quotient that is used to assess overall turf performance qualities on a relative scale over time. Using an integrated Global Positioning System (GPS), the TPI measurements can be used to identify overall property conditions and zone specific conditions within that property. Such analysis is viewed with visual analysis methods using a cloud based system. | 2017-12-21 |
20170363552 | APPARATUS AND METHOD FOR PRODUCING AND ANALYZING A PLURALITY OF SAMPLE MATERIALS - An apparatus for producing and analyzing sample materials may comprise a milling device for milling material components, a first metering device for metering a material component into the milling device, a second metering device for metering an activator liquid into the milled material component, a homogenization device for homogenizing the material components and the activator liquid to produce a sample material, a control device that is connected to the milling device and is configured to vary a parameter characteristic for milling intensity of the milling device so that particle size of the material components is altered, and a measuring device for determining a reactivity of the sample material. The present disclosure further concerns a process for producing and analyzing a plurality of sample materials. The process may involve varying at least one parameter characteristic for milling intensity for each sample material produced. | 2017-12-21 |
20170363553 | SEALANT DETECTION APPARATUS, METHOD AND ASSEMBLY - Apparatus, assembly and method for investigating the integrity of a seal and sealant contained in a sealing fitting used in hazardous locations. The apparatus/assembly can include signal transmitters and signal receivers provided on a conduit system on either side of a sealing fitting. The apparatus/assembly can include probes placed on either side of a sealant within a sealing fitting, the probes placed in probe ports provided through the wall of the sealing fitting. | 2017-12-21 |
20170363554 | RADIO FREQUENCY IDENTIFICATION MONITORING OF STENTS - A method and system of monitoring environmental exposure of stents using radiofrequency identification is disclosed. | 2017-12-21 |
20170363555 | SENSING SYSTEM AND AN ASSOCIATED METHOD THEREOF - A sensing system for monitoring an industrial fluid is presented. The sensing system includes a housing and a sensor probe disposed at least partially in the housing, where the sensor probe includes a substrate, a sensing region disposed on the substrate, a first coil disposed on the substrate and coupled to the sensing region, and a second coil disposed on the substrate and coupled to the first coil. A method for operating the sensing system is also presented. | 2017-12-21 |
20170363556 | GAS SENSOR - A gas sensor includes an adsorption layer configured to cause gas to adsorb thereon, the gas including a target gas and a non-target gas, and a sensor layer covered with the adsorption layer and having an electric characteristic thereof changing in response to density of the target gas passing through the adsorption layer, wherein the adsorption layer is made of a material whose primary component is a metal oxide having gold particles attached thereto. | 2017-12-21 |
20170363557 | MONITORING A STRUCTURE FOR DAMAGE - A structure to be monitored for damage and a method of monitoring the structure for damage are provided. The structure has a coating thereon, the coating defining a surface having characteristics which vary in a predetermined manner with damage to the structure. The surface has a series of conductive tracks applied thereto and in intimate contact therewith such that the said predetermined variation of the surface characteristics will vary the resistance of the series of conductive tracks in a predetermined manner in order to determine both location and extent of damage. | 2017-12-21 |
20170363558 | TIRE INSPECTION APPARATUS - A tire inspecting apparatus for a tire is provided. The apparatus includes a test stand for supporting and rotating a tire. The test stand is configured such that a tire supported thereon defines a center axis. The apparatus includes a testing probe configured as a high voltage electrode for generating an electric field and a grounding element. A positioning assembly includes a support bracket and a positioning arm supporting the testing probe. The positioning arm is operable to move the testing probe into a working position between the sidewalls of a tire supported on the test stand and in proximity to the grounding element. The positioning arm is connected to the support bracket for pivoting movement relative to the support bracket about a pivot axis. The pivot axis extends at a non-perpendicular angle relative to the center axis of a tire supported on the test stand. | 2017-12-21 |
20170363559 | SYSTEMS AND METHODS FOR DETERMINING ROTOR DETERIORATION IN A DYNAMOELECTRIC MACHINE - Embodiments of the disclosure are directed at determining rotor deterioration in a dynamoelectric machine. Various current and voltage measurements are carried out upon an exciter assembly when the dynamoelectric machine is operated at various speeds and at various occasions over an extended period of time. More particularly, a set of current and voltage measurements that are carried out when the dynamoelectric machine is in a slow-roll mode of operation can be used for determining a resistance of a current path through which the exciter assembly provides electrical power to a rotor assembly. A time-domain-to-frequency-domain conversion can be carried out upon this set of resistance measurements in order to generate a spectral signature. The spectral signature can then be evaluated to detect an altered rotor resistance condition and/or a rotor resistance alteration trend. | 2017-12-21 |
20170363560 | Method for Non-Linear High Salinity Water Cut Measurements - The present disclosure relates to a method for determining a water cut value of a composition comprising a hydrocarbon. In some embodiments, the disclosure relates to an apparatus for determining the water cut value of the composition that comprises one or more of a capacitance probe, a temperature probe, a salinity probe, and a computer. | 2017-12-21 |
20170363561 | High Capacity Redox Electrodes and Their Use in Cell Lysis - The present disclosure relates to the manufacture and use of redox electrodes and their use in cell lysis. In certain embodiments, the redox electrodes are manufactured using a hybrid material approach, such as using a redox polymer in combination with a support substrate, such as cellulose fibers or paper. In certain implementations, the redox electrodes are suitable for use at voltages greater than 25 Volts. | 2017-12-21 |
20170363562 | ELECTROCHEMICAL DETECTION SYSTEM AND METHOD OF OPERATION - An electrochemical detection system for determining a concentration of a gas in exhaust gases of a combustion process. The system includes an electrolyte, a reference electrode, and a sense electrode that cooperate to form an electrochemical sensor that exposes both the reference electrode and the sense electrode to the exhaust gases. The electrochemical sensor is configured to output a sensor signal indicative of a species concentration of a species gas in the exhaust gases. The sensor signal exhibits a transient error in response to a change in a reference concentration of a reference gas in the exhaust gases. The processor is configured to determine the species concentration based on the sensor signal, and to determine an estimate of the transient error based on an operating condition of the combustion process. | 2017-12-21 |
20170363563 | CARBON NANOTUBE BASED REFERENCE ELECTRODES AND ALL-CARBON ELECTRODE ASSEMBLIES FOR SENSING AND ELECTROCHEMICAL CHARACTERIZATION - A carbon nanotube-based reference electrode and an all-carbon nanotube microelectrode assembly for electrochemical sensing and specialized analytics are disclosed, along with methods of manufacture, and applications including detection of ionic species including heavy metals in municipal and environmental water, monitoring of steel corrosion in steel-reinforced concrete, and analysis of biological fluids. | 2017-12-21 |
20170363564 | Electrodes Having at Least One Sensing Structure and Methods for Making and Using the Same - Embodiments of the present disclosure relate to electrochemical analyte sensor electrodes that have one or more sensing structures, each structure has a respective perimeter at least partially around it to define the structure so that each of the structures have a liquid limiting barrier around their perimeters. The liquid limiting perimeter may completely or partially encompass the perimeter of each sensing structure of the electrode. Also provided are methods for fabricating the electrodes, analyte sensors employing the subject electrodes, and methods of using the analyte sensors in analyte monitoring. | 2017-12-21 |
20170363565 | Analyte Measurement - A method for configuring a device to determine a concentration of an analyte uses a plurality of m fluid samples, each having a corresponding known analyte concentration. The method includes, for each sample: generating an output signal from the sample; recording values of the signal over time; and modelling a subset of the values of the signal using n basis functions to obtain n coefficients. Each coefficient is associated with a corresponding basis function, the n basis functions and n coefficients representing the signal for the subset. The method also includes performing a statistical analysis of the m×n coefficients and corresponding known analyte concentrations to determine a set of n parameters from which an analyte concentration can be estimated based on a set of n coefficients obtained for a sample for which the analyte concentration is unknown; and storing the set of n parameters in a memory of a device. | 2017-12-21 |
20170363566 | Method of Determining Parameters of a Test Fluid - Determining first and second parameters of a fluid sample includes obtaining a first data set including data from output signals as a function of pluralities of the first and second parameters. The method includes applying an autocorrelation function to the output signals set so as to obtain a second data set including data from a plurality of autocorrelation signals as a function of the pluralities of the first and second parameters. The method includes generating a test output signal at a device by reacting the device with the fluid sample, applying the autocorrelation function to the test output signal so as to obtain a test autocorrelation signal, identifying in the first and second data sets an intersection of data from the test output signal with corresponding data from the test autocorrelation signal, and determining the first and second parameters of the sample based on the intersection. | 2017-12-21 |
20170363567 | METHOD FOR CALIBRATING A DEVICE FOR MEASURING THE CONCENTRATION OF CREATININE - A method of calibrating a device for measuring the concentration of creatinine using one or more calibration solutions, the method comprising: receiving concentrations at an initial time of creatine, Cr, and/or creatinine, Crn, of the one or more calibration solutions; receiving outputs of the measuring device at the end time; calculating the concentration of Cr and/or Crn in the calibration solutions at an end time using a temperature model, wherein the temperature model indicates changes in temperature of the calibration solutions from the initial time to the end time; and determining a relationship between the outputs of the measuring device and the calculated concentrations of Cr and/or Crn. | 2017-12-21 |
20170363568 | CALIBRATION CONCEPT FOR AMPEROMETRIC CREATININE SENSOR CORRECTING FOR ENDOGENOUS MODULATORS - A method of calibrating a device for measuring the concentration of creatinine in a sample including one or more enzyme modulators, the method comprising: determining sensitivities of the device for each of two or more calibration solutions, wherein each calibration solution has a different amount of enzyme modulator; determining a degree of modulation for each of the two or more calibration solutions; determining a degree of modulation for a sample to be measured; and calculating the sensitivity of the device for the sample, wherein said calculating comprises modifying the sensitivity of one of the two or more calibration solutions by a function comprising the determined degrees of modulation. | 2017-12-21 |
20170363569 | DEVICES AND METHODS FOR MEASURING THE PROPERTIES OF MACROMOLECULES - Devices for use in determining properties of biochemicals and macromolecules derived from a biological sample include a fluid control unit and a macromolecule measurement unit integrated on a monolithic platform. Devices and methods of measuring the properties of macromolecules using immobilized magnetic particles are also disclosed. | 2017-12-21 |
20170363570 | GAS SENSOR AND METHOD FOR MANUFACTURING THE SAME - A gas sensor having a reliable measurement accuracy for specific gases even if a pump electrode is heated and a method for manufacturing the same are provided. The gas sensor is provided with a measurement target gas chamber, a reference gas chamber, a solid electrolyte, a pump electrode, a sensor electrode, a reference electrode and a heater. The pump electrode includes Pt, Au and an aggregate. After the gas sensor has been manufactured, in a state that the pump electrode has not been heated to an activation temperature of the solid electrolyte yet, in the pump electrode, a pore is 5.2 vol % or less, a surface roughness Ra is 0.5 μm to 9.1 μm, and a content ratio of the aggregate | 2017-12-21 |
20170363571 | ELECTROCHEMICAL TESTING SYSTEM - An electrochemical testing system, including: a testing board including: a plurality of testing wells, each well including a first well portion for holding a workpiece to be tested and bringing a first surface of the workpiece into contact with a separate working electrode lead for each testing well, a second well portion for holding a testing media and bringing a second surface of the workpiece into contact with the testing media, and a sealing mechanism for preventing contact of the testing media and the first surface of the workpiece; a media delivery system for selectively delivering the testing media into the second well portion; at least one sensing head for securing one or more electrochemical sensing elements at least one of which is adapted to form part of an electro chemical circuit with the testing media, workpiece and working electrode lead for each testing well, each testing well being electrically and physically isolated from other testing wells; testing apparatus for measuring electrochemical and/or chemical properties from the electrochemical circuit; and a motion control system for controlling relative movement of the sensing head and the plurality of testing wells so that the one or more sensing elements are selectively brought into contact with the testing media in the testing well of a selected workpiece to be tested. | 2017-12-21 |
20170363572 | CONTAMINANT DETECTION DEVICE AND METHOD - A device for measuring pH levels and contaminant concentration includes an electrode assembly that is electrically coupled to a control unit. The electrode assembly includes a FLUID first contact electrically coupled to a reference electrode, a second contact electrically coupled to a working electrode, and a third contact electrically coupled to a counter electrode. The working electrode may be modified to include a cysteine functionalized graphene oxide with polypyrrole nanocomposite. In operation, the control unit may apply a complex signal to the working electrode via the second contact in order to adhere and subsequently strip contaminant ions from the fluid sample to the working electrode. During this process, a current may be measured across the reference electrode and the counter electrode to measure contaminant ion concentration. The pH of the fluid sample may also be determined by a current measured across the reference electrode and the counter electrode. In some examples, the pH may be used to calibrate the measured levels of the contaminant ions. | 2017-12-21 |
20170363573 | BIASING OF AN IONIC CURRENT SENSOR - An ionic current sensor array includes a master bias generator and a plurality of sensing cells. The master bias generator is configured to generate a bias voltage. Each sensing cell includes an ionic current sensor, an integrating capacitor, a sense transistor coupled between the integrating capacitor and the ionic current sensor, and an amplifier coupled to provide a reference voltage to bias the ionic current sensor. The amplifier includes a first transistor and a second transistor. The first transistor is coupled to receive the bias voltage, and the second transistor is coupled to the first transistor to provide the reference voltage to the ionic current sensor. The second transistor is also coupled between a source of the sense transistor and the gate of the sense transistor. | 2017-12-21 |
20170363574 | Gel Electrophoresis and Transfer Combination using Conductive Polymers and Method of Use - A precast gel and blotting membrane combination unit and method of use. The device includes two plates, each plate having a conductive opaque region with conductive polymers and a transparent region having static-dissipative polymers. Between the plates are a gel matrix and blotting membrane. The device is placed in a tank capable of both performing the electrophoresis phase and transfer phase of a western blot. During the electrophoresis phase, current flows from a pair of electrophoresis electrodes to separate proteins by size. The user can visualize the extent of protein separation by observing a tracking dye through the transparent region. After the electrophoresis phase, voltage is switched to a pair of transfer phase electrodes. The device allows current to flow through the conductive opaque regions of the plates to transfer separated proteins to a blotting membrane directly after electrophoresis without having to remove or reorient the device in the tank. | 2017-12-21 |
20170363575 | APPARATUS AND METHOD FOR SEPARATING MOLECULES - Apparatuses and methods for whole column imaging detection (WCID) capillary isoelectric focusing (CIEF). The apparatus includes a separation capillary having a separation inner diameter and a separation outer diameter; a base, wherein the separation capillary is anchored to the base; an inlet transfer capillary having an inlet inner diameter and an inlet outer diameter; and an outlet transfer capillary having an outlet inner diameter and an outlet outer diameter. The inlet transfer capillary, the separation capillary, and outlet transfer capillary are configured to be in fluidic communication with each other. The separation inner diameter exceeds the outlet inner diameter. | 2017-12-21 |
20170363576 | SYSTEM FOR CAPILLARY ELECTROPHORESIS FOR PEPTIDE AND PROTEIN ANALYSIS - The invention provides a novel method of coating the inside of a capillary with a polymeric material. The method can include introducing a catalyst-free solution of a monomer and initiator, wherein the monomer is present in about 1-10% (w/v) and the initiator is present in 0.1-1% (w/v), into a capillary and thermally initiating polymerization of the monomer thereby providing a capillary comprising an internal polymeric coating for separating, identifying, and quantifying components of an analyte. | 2017-12-21 |
20170363577 | FORMATION OF LAYERS OF AMPHIPHILIC MOLECULES - To form a layer separating two volumes of aqueous solution, there is used an apparatus comprising elements defining a chamber, the elements including a body of non-conductive material having formed therein at least one recess opening into the chamber, the recess containing an electrode. A pre-treatment coating of a hydrophobic fluid is applied to the body across the recess. Aqueous solution, having amphiphilic molecules added thereto, is flowed across the body to cover the recess so that aqueous solution is introduced into the recess from the chamber and a layer of the amphiphilic molecules forms across the recess separating a volume of aqueous solution introduced into the recess from the remaining volume of aqueous solution. | 2017-12-21 |
20170363578 | METHOD AND DEVICE FOR BIOMOLECULE PREPARATION AND DETECTION USING MAGNETIC ARRAY - An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises multiple zones such as a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array or a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte. | 2017-12-21 |
20170363579 | SENSORY ELEMENTS FOR PULSED EDDY CURRENT PROBE - Sensory elements for placement within a probe that includes at least one receiving coil disposed within a pulsed eddy current probe, and at least one sensing element disposed within a pulse eddy current probe. | 2017-12-21 |
20170363580 | SLUG FLOW MONITORING AND GAS MEASUREMENT - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for monitoring slug flow in subterranean wells. In one aspect, a method includes at a time instant, transmitting an acoustic signal across a cross-section of a pipeline flowing multiphase fluid including gaseous fluid and liquid fluid, wherein a portion of the acoustic signal is carried through the cross-section of the pipeline by the multiphase fluid and determining, at the time instant, a first quantity of the gaseous fluid and a second quantity of the liquid fluid passing the cross-section of the pipeline based, in part, on an energy of the portion of the acoustic signal carried through the cross-section and at least a portion of a total energy of the transmitted acoustic signal. | 2017-12-21 |
20170363581 | Electro-Acoustic Sensors For Remote Monitoring - Ultrasonic transmitting elements in an electroacoustical transceiver transmit acoustic energy to an electroacoustical transponder, which includes ultrasonic receiving elements to convert the acoustic energy into electrical power for the purposes of powering one or more sensors that are electrically coupled to the electroacoustical transponder. The electroacoustical transponder transmits data collected by the sensor(s) back to the electroacoustical transceiver wirelessly, such as through impedance modulation or electromagnetic waves. A feedback control loop can be used to adjust system parameters so that the electroacoustical transponder operates at an impedance minimum. An implementation of the system can be used to collect data in a vehicle, such as the tire air pressure. Another implementation of the system can be used to collect data in remote locations, such as in pipes, enclosures, in wells, or in bodies of water. | 2017-12-21 |
20170363582 | METHOD AND SYSTEM FOR OBLIQUE BACKSCATTERING ULTRASOUND IMAGING - An Oblique Backscatter Ultrasound imaging system includes a transceiver that has an US source and a plurality of US detectors configured in receive signals off axis from the US source. While the system is arranged in a reflective configuration, the device produces transmissive contrast signals to yield improved images. The transceiver can be mounted to a movable stage or robotic arm to enable it to scan the surface of a target. Alternatively, scanning can be performed by 1D or 2D phased-array transmission or detection. | 2017-12-21 |
20170363583 | FLEXIBLE ULTRASONIC TRANSDUCER AND A TRANSDUCER BLOCK - A flexible ultrasonic transducer comprising a flexible metal plate, a piezoelectric ceramics element, a first electrical conductor and an insulation covering a portion of the metal plate. The metal plate comprises a first and a second outer surface opposite each other. The piezoelectric ceramics element is attached to the first outer surface, a first portion of the first outer surface is not covered with the piezoelectric ceramics element, and the first electrical conductor is attached to a first portion of the second outer surface or the first portion of the first outer surface. The first portion of the first outer surface and the first portion of the second outer surface have similar dimensions and positions and the insulation covering covers the first portion of the first outer surface so that the piezoelectric ceramics element is directly dry coupled an object to be inspected by means of the transducer. | 2017-12-21 |
20170363584 | SAW MAGNETIC SENSOR AND MANUFACTURING METHOD FOR SAME - A SAW (Surface Acoustic Wave) magnetic sensor includes: a piezoelectric thin film; a seed layer; an interdigital transducer arranged respectively on each side of the piezoelectric thin film, the interdigital transducer comprising an interdigital electrode made from magnetic materials, and reflector grids located at both ends of the interdigital electrode; an underlying substrate arranged at the seed layer opposite to the piezoelectric thin film. A manufacturing method for the sensor is also disclosed. | 2017-12-21 |
20170363585 | DETERMINING MECHANICAL PROPERTIES VIA ULTRASOUND-INDUCED RESONANCE - A device for estimating a mechanical property of a sample is disclosed herein. The device may include a chamber configured to hold the sample; a transmitter configured to transmit a plurality of waveforms, including at least one forcing waveform; and a transducer assembly operatively connected to the transmitter and configured to transform the transmit waveforms into ultrasound waveforms. The transducer assembly can also transmit and receive ultrasound waveforms into and out of the chamber, as well as transform at least two received ultrasound waveforms into received electrical waveforms. The device also includes a data processor that can receive the received electrical waveforms; estimate a difference in the received electrical waveforms that results at least partially from movement of the sample; and estimate a mechanical property of the sample by comparing at least one feature of the estimated difference to at least one predicted feature, wherein the at least one predicted feature is based on a model of an effect of the chamber wall. Finally, the device can also include a controller configured to control the timing of the ultrasound transmitter and data processor. | 2017-12-21 |
20170363586 | Structure Evaluation System, Structure Evaluation Apparatus, and Structure Evaluation Method - According to an embodiment, a structure evaluation system includes a plurality of AE sensors, a signal processor, a position locator, and an evaluator. The AE sensors detect an elastic wave generated from a structure. The signal processor performs signal processing on the elastic wave detected by the AE sensors and outputs an AE signal including information on the elastic wave. The position locator derives a source distribution indicating the distribution of sources of the elastic wave generated in the structure, using an AE signal caused by an impact on the structure. The evaluator evaluates a state of deterioration of a predetermined region of the structure from a density of the sources of the elastic wave obtained on the basis of the source distribution. | 2017-12-21 |
20170363587 | STRUCTURE EVALUATION SYSTEM, STRUCTURE EVALUATION APPARATUS, AND STRUCTURE EVALUATION METHOD - According to an embodiment, a structure evaluation system includes a plurality of sensors, a position locator, and an evaluator. The sensors detect an elastic wave generated from a structure. The position locator derives a source distribution of the elastic waves generated from the structure, caused by an impact on the structure. The evaluator evaluates a state of deterioration of the structure from characteristic parameters of the elastic waves in the source distribution. | 2017-12-21 |
20170363588 | A MEMS Gas Chromatograph and Method of Forming a Separator Column for a MEMS Gas Chromatograph - A micro gas chromatograph includes one or more separator columns formed within a device layer. The separator columns have small channel cross sections and long channel lengths with atomic-smooth channel sidewalls enabling a high channel packaging density, multiple channels positioned on top of each other, and channel segments that are thermally decoupled from the substrates. The micro gas-chromatograph also enables electrostatic and thermal actuators to be positioned in close proximity to the separator columns such that the material passing through the columns is one or more of locally heated, locally cooled, and electrically biased. | 2017-12-21 |
20170363589 | Thermal conductivity sensing device, Methods for operation and uses of the Same - A thermal conductivity sensing device ( | 2017-12-21 |
20170363590 | DISPENSING NEEDLE FOR A FRACTION COLLECTOR - Described is a dispensing needle for a fraction collector. The dispensing needle includes a conduit having a fluid channel to conduct a chromatographic flow, an interior wall that defines the fluid channel, an exterior surface and an endface through which the chromatographic flow is dispensed. The dispensing needle also includes a coating of a hydrocarbon material or a fluorocarbon material that is bonded to the endface. The coating is also bonded to at least a portion of the exterior surface that is adjacent to the endface and at least a portion of the interior wall that is adjacent to the endface. The coating operates to reduce a droplet volume of a liquid dispensed from the endface that may remain at the tip of the dispensing needle. Consequently, the concentration variation in a collected fraction due to a missing droplet or extra droplet is reduced. | 2017-12-21 |
20170363591 | CHARACTERIZATION OF CRUDE OIL BY SIMULATED DISTILLATION - A system and a method is provided for calculating and assigning one or more indicative properties (e.g., cetane number, pour point, cloud point and/or aniline point) of a fractions of a crude oil sample based upon gas chromatographic simulated distillation data. | 2017-12-21 |
20170363592 | CHARGE REVERSIBLE ION EXCHANGE RESINS, CHROMATOGRAPHY COLUMN, METHOD, AND SYSTEM THEREOF - An ion exchange chromatographic packing material is described that includes a copolymer grafted to support resin particles. The copolymer includes an ion exchange group, an ionic crosslinking group configured to ionically bind to the ion exchange group, and an adjustable ionization state group having at least a first net charge at the first pH and a second net charge at the second pH. An overall first net charge of the chromatographic packing material at the first pH is opposite in polarity to the overall second net charge of the chromatographic packing material. This allows impurities to be removed from the chromatographic packing material at the second pH. | 2017-12-21 |
20170363593 | METHOD FOR MEASURING THE CONCENTRATION OF A CHEMCIAL SPECIES USING A REAGENT BASELINE - A method in which a concentration of a chemical species of interest is obtained. The method comprises measuring a property (e.g. the oxidation reduction potential) of a reagent (typically based on a simple single electron redox couple) to obtain a baseline measurement. The reagent is mixed with the solution under test, then the property of the mixture is measured to obtain a post reaction measurement. Then the concentration of the chemical species of interest is determined based on the baseline measurement and the first post reaction measurement, typically by calculating a difference of the baseline measurement and the post reaction measurement, then using the difference and a pre-determined conversion table to determine the concentration of the chemical species of interest. | 2017-12-21 |
20170363594 | FILM BASED CARBON DIOXIDE SENSOR - A gas concentration monitoring system ( | 2017-12-21 |
20170363595 | SYSTEM AND METHOD FOR CALIBRATION OF VOLATILE ORGANIC COMPOUND DETECTING INSTRUMENTS - Embodiments relate generally to systems and methods for calibrating a gas detector. Some embodiments may include a gas detector comprising one or more sensing elements operable to detect volatile organic compounds (VOC), and a probe operable to provide air flow into the gas detector, wherein the probe comprises: a housing operable to attach to a main body of the gas detector and operable to hold a calibration tube during calibration of the gas detector; a cap operable to attach to the housing and operable to fit over and cover the calibration tube; and one or more inlets, wherein when a calibration tube is inserted into the probe, the air flows through the calibration tube. In some embodiments of the gas detector, the calibration tube inserted into the probe comprises activated carbon fiber (ACF) filter material. | 2017-12-21 |
20170363596 | GAS SENSOR - A gas sensor | 2017-12-21 |
20170363597 | GAS SENSOR - A gas sensor | 2017-12-21 |
20170363598 | GAS SENSOR - A gas sensor | 2017-12-21 |
20170363599 | GAS SENSOR - An inner protective cover | 2017-12-21 |
20170363600 | METHODS FOR DETECTING AND QUANTIFYING ANALYTES USING GAS SPECIES DIFFUSION - Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of a gas sensor to a control sample of a known interrogator gas is determined. The gas sensor is exposed to a test sample then to a second sample comprising the known interrogator gas, and a test sample response profile of the gas sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample. | 2017-12-21 |
20170363601 | WIRELESS SYSTEM AND METHOD FOR MEASURING AN OPERATIVE CONDITION OF A MACHINE - A system includes a sensor configured to be disposed within a reservoir of a machine having moving parts that are lubricated by a liquid in the reservoir. The sensor is configured to obtain a measurement of the liquid that is representative of at least one of a quantity or quality of the liquid in the reservoir. The system also includes a device body operably coupled to the sensor. The device body has a processing unit that is operably coupled to the sensor and configured to generate first data signals representative of the measurement of the liquid. The device body also includes a transmitter that is configured to wirelessly communicate the first data signals to a remote reader. | 2017-12-21 |
20170363602 | CHARACTERIZATION OF CRUDE OIL BY FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY - A system, method and computer program product are provided for calculating one or more indicative properties, e.g., one or more of the cetane number, octane number, pour point, cloud point and aniline point of oil fractions, from the density and Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) of a sample of an oil sample. | 2017-12-21 |
20170363603 | CHARACTERIZATION OF CRUDE OIL BY HIGH PRESSURE LIQUID CHROMATOGRAPHY - A system and a method are provided for calculating one or more indicative properties, e.g., one or more of the cetane number, octane number, pour point, cloud point and aniline point of oil fractions, from the density and high pressure liquid chromatography (HPLC) data of a sample of the crude oil. | 2017-12-21 |
20170363604 | APPLICATIONS OF SPECTRAL FINGERPRINTING OF HYDROCARBONS AND OTHER ORGANICS - A method of obtaining a spectra on a hydrocarbon containing sample, that may include (A) Contacting the sample with an ionic liquid to create a prepared sample, and/or may also include (B) Processing the prepared sample through a spectroscopic system to obtain a spectra corresponding to the sample, wherein the spectra is suitable for determining the presence of and identity of any organic materials present sample. The sample may comprise soil, fluids, plants, drill cuttings, drilling mud, cores, water, blood, food, formation tester samples, or combinations thereof. | 2017-12-21 |
20170363605 | Methods for Characterizing Branching Distribution in Polymers - New metrics are disclosed for characterizing polyethylene copolymers which can be computed from the Cross-Fractionation Chromatography data of these polymers. These metrics are able to quantify the Broad Orthogonal Composition Distribution (BOCD) character of the polymers, and they can be used to discriminate polymers with an enhanced BOCD character from polymers that have the BOCD character to a lesser extent or from polymers that have the conventional molecular weight distribution and/or branching distribution. | 2017-12-21 |
20170363606 | SENSOR - According to one embodiment, a sensor includes a nonmagnetic layer and a plurality of magnetic field sensors. The nonmagnetic layer has a first surface and a second surface. The magnetic field sensors are arranged along the second surface. The second surface is between the first surface and the magnetic field sensors. Each of the magnetic field sensors includes a first magnetic layer, a second magnetic layer provided between the first magnetic layer and the nonmagnetic layer, and an intermediate layer provided between the first magnetic layer and the second magnetic layer. The intermediate layer is nonmagnetic. A distance between the first surface and the second magnetic layer is not more than a pitch of the magnetic field sensors. | 2017-12-21 |
20170363607 | AMORPHOUS, POROUS SILICON MATERIALS AND RELATED METHODS - Provided herein are Si-based materials, methods of making the Si-based materials, and methods for using the Si-based materials. In embodiments, a silicon-based material comprises an aggregate of particles, the particles comprising an ordered array of nanostructures, the nanostructures comprising amorphous silicon, wherein at least some pairs of adjacent nanostructures are connected by one or more bridges comprising amorphous silicon, the one or more bridges extending from the surface of one nanostructure of the pair to the surface of the other nanostructure in the pair. | 2017-12-21 |
20170363608 | METHOD OF SETTING A HANDOVER POSITION AND LABORATORY AUTOMATION SYSTEM - A method of setting a handover position of a gripping device at a laboratory automation system is presented. A position of a position determining device held by the gripping device is detected using position sensors in order to determine the handover position. A laboratory automation system configured to perform such a method is also presented. | 2017-12-21 |
20170363609 | INTEGRATING NANOPORE SENSORS WITHIN MICROFLUIDIC CHANNEL ARRAYS USING CONTROLLED BREAKDOWN - Nanopore arrays are fabricated by controlled breakdown in solid-state membranes integrated within polydimethyl-siloxane (PDMS) microfluidic devices. This technique enables the scalable production of independently addressable nanopores. By confining the electric field within the microfluidic architecture, nanopore fabrication is precisely localized and electrical noise is significantly reduced during sensing. | 2017-12-21 |
20170363610 | METHOD OF CONTROLLING A BLOOD ANALYZER FOR MEASURING PLATELETS - A method of controlling a blood analyzer for measuring platelets is provided. The method comprises: determining a relationship between at least one first measurement value obtained by detecting platelets in at least one previous test by an electrical type detector of the blood analyzer and at least one second measurement value obtained by detecting the platelets in the at least one previous test by an optical type detector of the blood analyzer, and controlling the blood analyzer to prepare the first and/or second measurement sample for a current test according to the determined relationship. | 2017-12-21 |
20170363611 | SYSTEMS AND METHODS FOR AN EQUILIBRIUM WET BATH - A wet standard calibration system which utilizes a heat conducting foam with the liquid therein to serve as a primary heating device to avoid the need to include mechanical agitation. The system is particularly useful for generating a vapor comprising water and ethanol which can be used for the calibration of breath alcohol testers. | 2017-12-21 |
20170363612 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISORDERS - Methods and compositions for drug discovery, analysis and treatment of a proliferative disorder characterized by abnormal cells in a mammalian subject are provided according to aspects of the present invention which include administering a pharmaceutically effective amount of a combination of: a cytotoxic agent, a SET agonist and a SET ribosome antagonist. Methods and compositions according aspect of the present invention incorporate agents effective to regulate and/or affect selective translation in a cell characterized by abnormal proliferation, such as a cancer cell, thereby promoting death of the cell. | 2017-12-21 |
20170363613 | SIMULTANEOUS DETECTION OF CANNIBALISM AND SENESCENCE AS PROGNOSTIC MARKER FOR CANCER - The present inventors show that cannibal cells can undergo senescence after entosis in vivo and that the tumor suppressive protein p53 act as a repressor of this phenomenon. They therefore propose new tools to study the molecular pathways involved in the cannibalism process, for example by measuring the expression levels of p53 or splice variants thereof (such as Δ133TP53, TP53β, TP53γ or Δ40TP53), the release of extracellular ATP or purinergic P2Y2 receptor activity. The present inventors also demonstrated that the detection of senescent cannibal cells in breast adenocarcinoma obtained from patients treated with neo-adjuvant therapy positively correlates with good patient's response to treatment. Altogether, these results provide the first evidence that detection of cellular cannibalism and senescence simultaneously in tumors helps for the diagnosis of disease outcomes and for the prediction of treatment efficiency against cancer diseases. | 2017-12-21 |
20170363614 | Methods For Screening Therapeutic Compounds - Methods of selecting test compounds on the basis of their cellular response profiles are disclosed. For a given test compound, a cellular response is determined by introducing into an array of individually addressable microwells a population of cells comprising a plurality of cell types and contacting the cells with the test compound. The cellular response profile for the test compound is then compared to a desired cellular response profile, and the test compound is selected based on the comparison. | 2017-12-21 |
20170363615 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS AND CELL LINES THAT EXPRESS SAID RECEPTORS AND USE THEREOF FOR IDENTIFICATION OF TASTE COMPOUNDS - The present invention relates to the discovery that the T1R receptors assemble to form functional taste receptors. Particularly, it has been discovered that co-expression of T1R1 and T1R3 results in a taste receptor that responds to umami taste stimuli, including monosodium glutamate. Also, it has been discovered that co-expression of the T1 R2 and T1R3 receptors results in a taste receptor that responds to sweet taste stimuli including naturally occurring and artificial sweeteners. | 2017-12-21 |
20170363616 | PATTERNED NEUROMUSCULAR JUNCTIONS AND METHODS OF USE - Disclosed herein are devices including a substrate, one or more regions of electrically active material, and optionally at least one electrode. Also disclosed herein are devices or systems including a substrate, one or more regions of electrically active material including muscle cells and neuronal cells, and optionally at least one electrode. In some embodiments, the muscle cells and neuronal cells form one or more neuromuscular junctions at defined locations on the electrically active material. Also disclosed are methods of using the devices and systems for analyzing the effect of compounds on neuronal cell, muscle cell and/or neuromuscular junction activity. | 2017-12-21 |
20170363617 | METHODS FOR NON-INVASIVE PROFILING OF STEM CELL DIFFERENTIATION - A method for characterizing stem cell differentiation includes harvesting differentiation media supernatant containing secreted analytes from key time points during a stem cell differentiation, performing at least one of a qualitative and a quantitative analysis of the differentiation media supernatant with respect to at least one secreted analyte, and identifying trends in analyte expression based on at least one of the qualitative and quantitative analysis of the differentiation media supernatant. | 2017-12-21 |
20170363618 | AGE-MODIFIED CELLS AND METHODS FOR MAKING AGE-MODIFIED CELLS - Provided are age-modified cells and method for making age modified cells by reducing or increasing the level of genomic nucleic acid methylation in the cells. The aging and/or maturation process can be accelerated or reduced and controlled for young, aged, mature and/or immature cells, such as a somatic cell, a stem cell, a stem cell-derived somatic cell, including an induced pluripotent stem cell-derived cell, by reducing or increasing the level of genomic nucleic acid methylation in the cells. Methods described by the present disclosure can produce age-appropriate cells from a somatic cell or a stem cell, such as an old cell, young cell, immature cell, and/or a mature cell. Such age-modified cells constitute model systems for the study of late-onset diseases and/or disorders. | 2017-12-21 |
20170363619 | ANIMAL MODEL FOR DIABETIC COMPLICATIONS - The invention relates to the surprising find that low density lipoprotein receptor-deficient mice (LDLr | 2017-12-21 |
20170363620 | BIOMARKERS TO PREDICT NEW ONSET HEART FAILURE WITH PRESERVED EJECTION FRACTION (HFpEF) - The invention provides methods of detecting a natriuretic protein, a troponin, and galectin-3 in samples from subjects in order to determine risk of developing new onset heart failure with preserved ejection fraction (HFpEF). | 2017-12-21 |
20170363621 | DETECTION OF ANALYTES IN BODILY FLUID TO DETERMINE THE INITIATION OF PARTURITION - Devices and kits for detecting molecular targets involved in the onset of parturition are presented, as are methods of using the same. The devices and kits include one or more associators specific for molecular targets, such as microRNAs and proteins and peptide fragments thereof. The associators, such as aptamers or antibodies, bind their targets, when such targets are present in a fluid sample from a pregnant woman, to produce a detectable signal. The signal may be produced in a lateral flow device. | 2017-12-21 |
20170363622 | Enzyme-Linked Immunosorbent Assay (ELISA) for the Detection of Anti-Mycoplasma hyorhinis IgG in Swine Serum - This disclosure presents an Enzyme-Linked Immunosorbent Assay (ELISA) for the selective detection of anti- | 2017-12-21 |
20170363623 | METHODS OF MEASURING POTENTIAL FOR THERAPEUTIC POTENCY AND DEFINING DOSAGES FOR AUTOLOGOUS CELL THERAPIES - Autologous bone marrow cells (BMC) are transplanted to a heterologous site in a patient after a sample of the patient's BMC has been tested and found to have a phenotypic profile which meets minimum criteria for transplantation. The phenotypic profile may be obtained by screening a sample of bone marrow cells (BMC) from the patient for the phenotypic profile, such as a CD profile, the phenotype profile may be assessed to determine the likelihood that the BMC will be suitable for transplantation to the heterologous tissue site without enriching particular phenotypic population(s) of the BMC. | 2017-12-21 |
20170363624 | METHOD OF IMMOBILIZING A CELL ON A SUPPORT USING COMPOUNDS COMPRISING A POLYETHYLENE GLYCOL MOIETY - The present invention relates to a method of immobilizing a cell on a support, the method comprising a) providing a compound or salt thereof comprising, preferably consisting of, one or more hydrophobic domains attached to a hydrophilic domain, wherein the one or more hydrophobic domains are covalently bound to said hydrophilic domain, and wherein the one or more hydrophobic domains each comprise a linear lipid, a steroid or a hydrophobic vitamin, and wherein the hydrophilic domain comprises a polyethylene glycol (PEG) moiety, and wherein the compound comprises a linking group; b) contacting a cell with the compound under conditions allowing the interaction of the compound with the membrane of the cell, thereby immobilizing the linking group on the surface of the cell; and c) contacting the linking group immobilized on the cell with a support capable of binding the linking group, thereby immobilizing the cell on the support. | 2017-12-21 |
20170363625 | QUALITY ASSAYS FOR ANTIGEN PRESENTING CELLS - The present invention provides methods for evaluating the quality of a preparation of antigen presenting cells, such as dendritic cells. Assays for antigen-independent co-stimulation of T cells and for presentation of predetermined antigen by APCs are provided. | 2017-12-21 |
20170363626 | METHODS AND ANTISERA FOR ISOLATING AND IDENTIFYING SUBSETS OF CD8 T CELLS - Methods for identifying and isolating CD8 T cells that produce interleukin-13 upon activation are provided. The present methods leverage one or more newly-identified biomarkers to identify such CD8 T cells and, in certain cases, sort the same. Certain methods comprise obtaining a sample from a mammal, quantifying a level of expression of one or more biomarkers therein, and determining if the level of expression is elevated as compared, wherein an elevated expression level is indicative of an active disease state. Antisera and antibodies are also provided. In particular, an anti-C10orf128 antiserum formulated against a particular peptide is provided, such anti-C10orf128 antiserum characterized in that it identifies a subset of CD8 T cells that produce interleukin-13 upon activation. | 2017-12-21 |
20170363627 | REAGENT KIT USED FOR DETECTING LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2, AND PREPARATION METHOD AND APPLICATION FOR REAGENT KIT - A reagent kit used for detecting lipoprotein-associated phospholipase A2, and a preparation method for the reagent kit. The reagent kit comprises one or a plurality of first anti-lipoprotein-associated phospholipase A2 antibodies used for binding lipoprotein-associated phospholipase A2 to be measured, and one or a plurality of second anti-lipoprotein-associated phospholipase A2 antibodies marked with a trace marker and binding with the lipoprotein-associated phospholipase A2 to be measured at another site, different from the binding site of the lipoprotein-associated phospholipase A2 to be measured and the first anti-lipoprotein-associated phospholipase A2 antibodies. The reagent kit also comprises a displacing agent, so as to further increase the detection accuracy of the reagent kit. A method using the reagent kit for the detection of lipoprotein-associated phospholipase A2 may take serum as a detection sample, has high repeatability and high accuracy, and measures the concentration of lipoprotein-associated phospholipase A2 in the sample in a highly sensitive manner. | 2017-12-21 |
20170363628 | MEANS AND METHODS FOR NON-INVASIVE DIAGNOSIS OF CHROMOSOMAL ANEUPLOIDY - The invention relates to a prenatal diagnostic method for the determination of a fetal chromosomal aneuploidy in a biological sample obtained from a pregnant woman, which method comprises enrichment and quantification of selected cell-free deoxyribonucleic acid sequences showing consensus nucleosome binding regions. | 2017-12-21 |
20170363629 | BIOMARKERS AND TARGETS FOR CANCER IMMUNOTHERAPY - Provided herein are predictive biomarker signatures that identify patients as likely to benefit from TIL therapy. Also provided are tumor immunotherapy resistance pathways that may be targets of combination therapies to enhance TIL therapy. | 2017-12-21 |
20170363630 | METHODS FOR BREAST CANCER TREATMENT - Disclosed herein are methods for treating subjects with breast cancer, comprising determining a therapeutic regimen for cancer by measuring the level (amount) of proteins of one or more biomarkers. Also disclosed are methods of predicting or assessing therapeutic outcome for subject. | 2017-12-21 |
20170363631 | PLASMA AUTOANTIBODY BIOMARKERS FOR BASAL LIKE BREAST CANCER - Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3). | 2017-12-21 |
20170363632 | Biomarker Kit for Metastatic Breast Cancer Prognosis and Uses Thereof - Provided herein are kits for detecting and quantifying the level of a metastatic cancer biomarker(s) in a patient. The kits may contain a detection and quantifying means, such as, biomarker specific antibodies. Also provided are methods for determining a prognosis, a stratification and/or monitoring of a metastatic cancer in a patient. The level or activity of at least two biomarkers, such as obscurin, PI3K, E-cadherin, or N-cadherin is measured in a patient sample and compared to corresponding biomarkers in a control sample. A significant difference in the level or activity of the biomarkers between the patient sample and control is indicative of a metastatic cancer. In addition a method for treating a metastatic breast cancer via administration of a PI3K inhibitor and an agent that increases expression of obscurin is provided. | 2017-12-21 |
20170363633 | METHODS FOR DIAGNOSIS, PROGNOSIS AND METHODS OF TREATMENT - The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. | 2017-12-21 |
20170363634 | Soluble B7-H1 - This document features methods of evaluating mammals by assessing expression of B7-H1 in a body fluid. | 2017-12-21 |
20170363635 | Methods of Treating and Prognosing Nonhematopoietic Malignant Tumors - Provided herein are methods of treating a nonhematopoietic malignant tumor in a patient and methods of prognosing a nonhematopoietic malignant tumor in a patient, comprising administering to the patient a therapeutically effective amount of an agent that preferentially kills or inhibits proliferation or activity of leukocytes relative to nonhematopoietic cells. | 2017-12-21 |
20170363636 | Fluorescent Probe, Singlet Oxygen Detection Agent, and Singlet Oxygen Detection Method - An object of the present invention is to provide a fluorescent probe that easily penetrates a cell and is capable of selectively and efficiently detecting singlet oxygen generated in the cell, a singlet oxygen detection agent containing the fluorescent probe, and a singlet oxygen detection method using the fluorescent probe. The fluorescent probe for detecting singlet oxygen comprises a compound having a silicon-rhodamine skeleton and a skeleton that increases the fluorescence of the fluorescent probe after trapping singlet oxygen to be greater than the fluorescence before trapping singlet oxygen, or a salt, hydrate, or solvate thereof. | 2017-12-21 |
20170363637 | Method and Kit for Determining Risk of Preterm Birth and/or Birth of Low-Birth-Weight Baby - The present application relates to a method for determining a risk of preterm birth and/or low birth weight of a pregnant female comprising measuring a galectin-3 (Gal-3) level in a blood, plasma, or serum sample obtained from the pregnant female, or a kit or marker which may be used in the method. The present application also relates to a medicament effective to reduce a risk of preterm birth and/or low birth weight, a pharmaceutical composition comprising the medicament, or a method for reducing a risk of preterm birth and/or low birth weight of a pregnant female comprising administering the medicament or the pharmaceutical composition to the pregnant female. | 2017-12-21 |
20170363638 | Systems and Methods for Improving Loading Capacity of a Segmented Reaction Cell by Utilizing All Available Segments - A method for analyzing a sample includes trapping a first ion packet in a first segment of a multi-segment reaction cell; trapping a second ion packet in a second segment of the multi-segment reaction cell; and trapping a third ion packet in a third segment of the multi-segment reaction cell. At least one of the first, second, and third ion packets includes precursor ions, and at least another one of the first, second, and third ion packets includes reagent ions. The method further includes mixing the first, second, and third ion packets within the reaction cell to cause a reaction between the precursor ions and the reagent ions to form product ions. | 2017-12-21 |
20170363639 | PEPTIDES, DEVICES, AND METHODS FOR THE DETECTION OF ANAPLASMA ANTIBODIES - The invention provides populations of isolated peptides useful for the detection of antibodies that bind to | 2017-12-21 |
20170363640 | BIOMARKER FOR DIAGNOSING VASCULAR DISEASES AND THE USES THEREOF - Provided are a composition for diagnosing vascular disease including an agent measuring a level of interleukin 12 receptor β2 protein in the blood, and a kit for diagnosing vascular disease including the same. Further, provided is a method for diagnosing vascular disease, the method including the step of measuring a level of interleukin 12 receptor β2 protein in a blood sample separated from an individual suspected of having vascular disease. Furthermore, provided are a composition for preventing or treating vascular disease including an interleukin 12 receptor β2 activity inhibitor, and a method of screening a therapeutic agent for vascular disease, the method including the step of treating smooth muscle cells with a test agent for vascular disease treatment and measuring an expression level of interleukin 12 receptor β2. | 2017-12-21 |
20170363641 | METHODS AND DEVICES FOR FEMALE HEALTH MONITORING - The present invention relates to, in part, methods of improved healthcare in female subjects that, for example, relay on menstrual fluid sampling for long tem biomarker monitoring. | 2017-12-21 |
20170363642 | METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect Chitinase-3-like protein 1 as diagnostic and prognostic biomarker assays in renal injuries. | 2017-12-21 |
20170363643 | COMPOSITIONS AND METHODS FOR DETECTION OF SMN PROTEIN IN A SUBJECT AND TREATMENT OF A SUBJECT - Disclosed herein are compounds, compositions and methods for modulating splicing of SMN2 mRNA in a subject. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders, including spinal muscular atrophy. Also provided are kits for detecting the amount of SMN protein in a sample of cerebrospinal fluid. | 2017-12-21 |
20170363644 | COMPOSITIONS AND METHODS FOR USE IN DIAGNOSIS OF ALZHEIMER'S DISEASE - Provided are compositions and methods useful in the diagnosis of Alzheimer's Disease (AD). The methods involve immunologically testing A B biological samples for an amount of high molecular weight kininogen (HK) and cleaved high molecular weight kininogen (HKc), wherein determining less HK relative to a normal control, or determining more HKc relative to a normal control, or a combination thereof, aids in diagnosis of AD. Hybridomas and monoclonal antibodies bind with specificity to either HK alone, or to both HK and HKc. Kits for use in immunological AD testing using the mAbs are also provided. | 2017-12-21 |
20170363645 | Novel Method for the Detection of pGlu-Abeta Peptides - The invention relates to a highly sensitive method for the detection of pGlu-Abeta (pGlu-Aβ) peptides and the use of this method in the diagnosis of neurodegenerative diseases, such as Alzheimer's disease and Mild Cognitive Impairment. The invention further concerns a novel method for monitoring the effectiveness of a treatment of neurode-generative diseases by monitoring changes in the level of pGlu-Aβ peptides. | 2017-12-21 |