50th week of 2010 patent applcation highlights part 37 |
Patent application number | Title | Published |
20100316924 | FUEL CELL - A fuel cell is formed by stacking first cell units and second cell units alternately. An inlet buffer and an outlet buffer are formed on a surface of a first metal separator of the first cell unit. Bosses are provided in the inlet buffer and the outlet buffer of the first metal separator. An inlet buffer and an outlet buffer are formed on a surface of the second metal separator of the first cell unit. Continuous guide ridges are formed in the inlet buffer and the outlet buffer of the second metal separator. The bosses and the continuous guide ridges are provided at positions overlapped with each other in the stacking direction. | 2010-12-16 |
20100316925 | FUEL CELL SYSTEM - A fuel cell system including a fuel cell module, a heat generation module, and a fuel supplying module is provided. The fuel supplying module supplies a fuel gas to the heat generation module. Heat generated by the fuel gas burned in the heat generation module is used for heating the fuel cell module. | 2010-12-16 |
20100316926 | FUEL CELL SYSTEM - A fuel cell system performs feedback control with respect to a reactive gas supplying apparatus based on a proportional obtained by multiplying a deviation of an actual flow quantity from a target value of a reactive gas supplied to the fuel cell from the reactive gas supplying apparatus by a proportional gain and an integral term obtained by multiplying the deviation by an integration gain to perform time integration in such a manner that the actual flow quantity coincides with the target value, and changes an update arithmetic operation of the integral term in accordance with a value of the deviation. | 2010-12-16 |
20100316927 | EXHAUST GAS PURIFICATION SYSTEM FOR A FUEL CELL OR A FUEL CELL STACK - Provided is a fuel cell or a fuel cell stack, wherein a means for reducing the concentration of unreacted alcohol is disposed on the cathode exhaust gas side. This means comprises in particular an additional electrochemical cell, to which a voltage is applied and which at least partially converts the unreacted alcohol into CO | 2010-12-16 |
20100316928 | Fuel Cell System Module - A fuel cell system module ( | 2010-12-16 |
20100316929 | AQUEOUS FORMULATIONS COMPRISING POLYAROMATIC COMPOUNDS BEARING ACID GROUPS AND/OR SALTS OF ACID GROUPS, PROCESS FOR PRODUCING THEM, FURTHER FORMULATIONS PRODUCED USING THE AQUEOUS FORMULATIONS AND USE OF THE FURTHER FORMULATIONS IN FUEL CELLS - Process for producing aqueous formulations (A) comprising at least one polyaromatic compound bearing acid groups and/or salts of acid groups and also aqueous formulations (A) which have been produced according to the process of the invention. Also a process for producing dried formulations (B) by removing the water from the aqueous formulations (A) and also the dried formulations (B) themselves. In addition a formulation (C) comprising the dried formulation (B) of the invention and also water or an aqueous formulation (A) and a water-comprising formulation (D) comprising the aqueous formulation (A) of the invention or the formulation (C) of the invention and additionally at least 2% by weight of an organic solvent. Additionally dry formulations (E) which are obtained by removing water from the water-comprising formulations (D) of the invention. Also the use of the water-comprising formulations (D) of the invention and of the dry formulations (E) obtained from these for producing a polymer electrolyte membrane and also the polymer electrolyte membrane itself and a membrane-electrode assembly (MEA) and also a fuel cell comprising the polymer electrolyte membrane of the invention. | 2010-12-16 |
20100316930 | FUEL CELL HAVING A STABILIZED CATHODE CATALYST - A fuel cell ( | 2010-12-16 |
20100316931 | Electrocatalyst, Fuel Cell Cathode and Fuel Cell - The present invention is related to fuel cells and fuel cell cathodes, especially for fuel cells using hydrogen peroxide, oxygen or air as oxidant. A supported electrocatalyst ( | 2010-12-16 |
20100316932 | FUEL CELL MEMBRANE ELECTRODE ASSEMBLY - Fuel cell membrane electrode assemblies and fuel cell polymer electrolyte membranes are provided comprising bound anionic functional groups and polyvalent cations, such as Mn or Ru cations, which demonstrate increased durability. Methods of making same are also provided. | 2010-12-16 |
20100316933 | ELECTROLYTE MEMBRANE - The present invention relates to an electrolyte membrane including a graft polymer having a sulfonic acid group as a proton conductive group, in which, when the electrolyte membrane is divided into four equal parts in a thickness direction thereof, a content of the sulfonic acid group in each of outer regions is larger than a content of the sulfonic acid group in each of inner regions; in which A | 2010-12-16 |
20100316934 | FUEL CELL, METHOD OF MANUFACTURING FUEL CELL, AND UNIT CELL ASSEMBLY - The method of manufacturing a fuel cell including stacked unit cell constituent members sandwiched by separators includes the steps of arranging the unit cell constituent member in a first area on a first face of the separator; and forming a seal member made of elastic material such that the seal member is adhered or intimately attached to a second area including the first area on the first face of the separator, and that the seal member is unified with an edge portion of the unit cell constituent member. | 2010-12-16 |
20100316935 | ELECTROCHEMICAL CELLS CONNECTED IN FLUID FLOW SERIES - An electrochemical cell system for generating electrical power is disclosed. The electrochemical cell system comprises a plurality of fluidly connected electrochemical cells. Each electrochemical cell comprises an anode and a cathode. The anode is configured to permit a fluid comprising at least an electrolyte to flow in contact therewith to oxidize a fuel. The cathode is permeable to an oxidizer and is configured to receive electrons to reduce the oxidizer. The cathode and the anode are spaced apart to define a gap therebetween for receiving the fluid flow. The plurality of electrochemical cells are connected in fluid flow series such that, for each pair of fluidly connected electrochemical cells, the fluid flows from a first cell of the pair of cells to a second cell of the pair of cells. The plurality of electrochemical cells are connected electrically in series such that, for each pair of fluidly connected electrochemical cells, the cathode of the first cell of the pair is electrically connected to the anode of the second cell of the pair. | 2010-12-16 |
20100316936 | ELECTRICAL CONTACT ELEMENT FOR A FUEL CELL HAVING AN ULTRA-THIN CONDUCTIVE LAYER COATING - An electrically conductive fluid distribution element for use in a fuel cell includes a conductive metal substrate and a layer of conductive non-metallic porous media. The conductive non-metallic porous media has an electrically conductive material deposited along a surface in one or more metallized regions and having an average thickness less than about 40 nm. The metallized regions improve electrical conductance at contact regions between the metal substrate and the fluid distribution media. | 2010-12-16 |
20100316937 | ALLOY CATALYST FOR REDOX REACTION - An alloy catalyst for redox reaction which is capable of obtaining even superior catalytic activity comprises alloy particles of platinum and nickel, wherein the alloy particle is equipped at an outer surface with a crystal lattice plane represented by a Miller index {111}, and has an average particle diameter in a range of from 6 to 20 nm. The alloy particle preferably takes a shape selected from a regular octahedron, a truncated octahedron, a regular tetrahedron, and a truncated tetrahedron. | 2010-12-16 |
20100316938 | MULTI-CHIP RETICLE PHOTOMASKS - A multi-chip reticle, methods of designing and fabricating multi-chip reticles, a system for designing a multi-chip reticle, and a method of fabricating integrated circuit chips using the multi-chip reticle. The multi-chip reticle includes a transparent substrate having two or more separate chip images arranged in an array, each chip image of said two or more chip images having only one type of reticle image, wherein at least two of said two more chip images have different types of reticle images. | 2010-12-16 |
20100316939 | Photolithography Monitoring Mark, Photolithography Mask Comprising An Exposure Monitoring Mark, And Phase Shift Mask Comprising An Exposure Monitoring Mark - A photolithography monitoring mark on a substrate includes a plurality of sets of lines. Individual of the sets include a plurality of substantially parallel lines comprising different widths arrayed laterally outward in opposing lateral directions from an axial center of the set. The different widths decrease in each of the opposing lateral directions laterally outward from the axial center of the set. Other implementations are disclosed. | 2010-12-16 |
20100316940 | Photomask for Forming Contact Hole in Semiconductor Device - Disclosed is a photomask for forming a contact hole arranged on a wafer in a zigzag form along a transverse direction, including: a light transmitting substrate; a main pattern disposed on the light transmitting substrate with a zigzag form as an upper main pattern disposed in a relatively upper portion and a lower main pattern disposed in a relatively lower portion are arranged alternately along a transverse direction; a first lower auxiliary pattern extending in a vertical direction and disposed adjacently to a lower portion of the upper main pattern; a first upper auxiliary pattern extending in a vertical direction and disposed adjacently to an upper portion of the lower main pattern; a second lower auxiliary pattern extending in the transverse direction and connecting the first lower auxiliary patterns with each other; and a second upper auxiliary pattern extending in the transverse direction and connecting the first upper auxiliary patterns with each other. | 2010-12-16 |
20100316941 | SOLID-STATE IMAGING DEVICE PRODUCING METHOD AND EXPOSURE MASK - A solid-state imaging device producing method includes the steps of: applying a resist material onto a substrate in which a channel region is formed; forming a resist layer by exposure and development of the resist material using a mask, the resist layer having an opening and a thin-film portion, the mask having a first region through which light is transmitted and a second region through which a smaller quantity of light than that the light transmitted through the first region is transmitted; subjecting the substrate to ion implantation using the resist layer as a mask to form an impurity region; etching the substrate using the resist layer as a mask after the ion implantation to form an alignment mark; and forming an electrode on the impurity region and part of the channel region using the alignment mark as a reference. | 2010-12-16 |
20100316942 | PHOTOMASK MAKING METHOD - A photomask is manufactured from a photomask blank comprising a transparent substrate and a light-shielding film consisting of upper and lower layers of transition metal-containing silicon base materials, the content of O+N in the upper layer being higher than that of the lower layer. The light-shielding film is processed in two steps by fluorine dry etching through a resist pattern such that a lower portion of the film is left behind, and oxygen-containing chlorine dry etching for removing the remainder of the film. | 2010-12-16 |
20100316943 | ILLUMINATION OPTICAL SYSTEM, EXPOSURE APPARATUS, AND DEVICE MANUFACTURING METHOD - There is disclosed an illumination optical system which illuminates an illumination target surface on the basis of light from a light source, said illumination optical system comprising, a spatial light modulator having a plurality of optical elements arrayed two-dimensionally and being individually controllable, a distribution forming optical system which forms a predetermined light intensity distribution on an illumination pupil of the illumination optical system on the basis of light having traveled via the spatial light modulator, and a control unit which integrally controls postures of a group of optical elements according to a shape of the predetermined light intensity distribution formed on the illumination pupil, out of the plurality of optical elements. | 2010-12-16 |
20100316944 | TONER, DEVELOPER, TONER CONTAINER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS - An electrostatic image developing toner including a resin fine particle, and a toner material containing a polyester-based resin, wherein the electrostatic image developing toner is obtained by dissolving and/or dispersing the toner material containing the polyester-based resin in an organic solvent to prepare a toner material liquid, and dispersing the toner material liquid in an aqueous solvent containing the resin fine particle, and wherein the polyester-based resin contains a polyester resin obtained by polycondensation of an alcohol component with a carboxylic acid component containing a modified purified-rosin. | 2010-12-16 |
20100316945 | METHODS FOR MAKING CUSTOMIZED BLACK TONERS - According to embodiments illustrated herein, there is provided a black toner having a resin, an optional additive, and at least two or more colored pigments, and the at least two or more colored pigments are selected from the group consisting of a blue pigment, a green pigment, a red pigment. a magenta pigment, a cyan pigment, a yellow pigment, a white pigment, and mixtures thereof, and the black toner has a colorimetric value L* of about less than 30. | 2010-12-16 |
20100316946 | SELF EMULSIFYING GRANULES AND SOLVENT FREE PROCESS FOR THE PREPARATION OF EMULSIONS THEREFROM - A process for making a self-emulsifying composite suitable for use in forming latex emulsions includes contacting a resin with a solid or highly concentrated surfactant, a solid neutralizing agent in the absence of water and an organic solvent to form a mixture, melt mixing the mixture, and forming a self-emulsifying composite of the melt mixed mixture such as a granule. Self-emulsifying granules are also provided and configured to form a latex emulsion when added to water, which may then be utilized to form a toner. | 2010-12-16 |
20100316947 | METHOD FOR PRODUCING RESIN EMULSION - The present invention relates to a resin emulsion which has a good emulsification performance even when produced by using a crosslinked polyester resin having a good fusing ability and a good durability, and also is capable of producing a toner having an excellent heat-resistant storage property therefrom; and a process for producing the resin emulsion. The process for producing a resin emulsion according to the present invention, includes the steps of: (a) mixing a resin containing a polyester having a constitutional unit derived from at least one component selected from the group consisting of a trivalent or higher-valent alcohol component and a trivalent or higher-valent carboxylic acid component, an anionic surfactant, and a nonionic surfactant with each other at a temperature which is not lower than a temperature lower by 10° C. than a softening point of the resin, the nonionic surfactant being used in an amount of more than 1.0 part by weight and less than 5 parts by weight on the basis of 100 parts by weight of the resin; and (b) neutralizing the resulting mixture obtained in the step (a) with a basic compound in an aqueous medium at a temperature not higher than the softening point of the resin. | 2010-12-16 |
20100316948 | TONER FOR DEVELOPING ELECTROSTATIC LATEMT IMAGE, DEVELOPER INCLUDING THE TONER, AND IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS USING THE DEVELOPER - A toner for developing electrostatic latent images, including a binder resin; a colorant; and a release agent, wherein the toner has a glass transition temperature (Tg) of from 55 to 75° C., a melting point (T | 2010-12-16 |
20100316949 | Spin On Organic Antireflective Coating Composition Comprising Polymer with Fused Aromatic Rings - The present invention relates to an organic spin on hard mask antireflective coating composition comprising a polymer comprising at least one unit of fused aromatic rings in the backbone of the polymer and at least one unit with a cycloaliphatic moiety in the backbone of the polymer. The invention further relates to a process for making the polymer and a process for imaging the present composition. | 2010-12-16 |
20100316950 | COMPOSITION FOR FORMING BASE FILM FOR LITHOGRAPHY AND METHOD FOR FORMING MULTILAYER RESIST PATTERN - A composition for forming an underlayer film for lithography for imparting excellent optical characteristics and etching resistance to an underlayer film for lithography, an underlayer film being formed of the composition and having a high refractive index (n) and a low extinction coefficient (k), being transparent, having high etching resistance, containing a significantly small amount of a sublimable component, and a method for forming a pattern using the underlayer film are provided. The composition for forming an underlayer film contains a naphthalene formaldehyde polymer having a specific unit obtained by reacting naphthalene and/or alkylnaphthalene with formaldehyde, and an organic solvent. | 2010-12-16 |
20100316951 | SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME - A salt having a group represented by the formula (I): | 2010-12-16 |
20100316952 | SALT AND PHOTORESIST COMPOSITION CONTAINING THE SAME - A salt represented by the formula (a1): | 2010-12-16 |
20100316953 | SILOXANE-BASED RESIN COMPOSITION - The present invention is a siloxane-based resin composition including a siloxane-based resin and an imidosilane compound having a specific structure. Moreover, the present invention is a siloxane-based resin composition including a siloxane-based resin which is a reactive product to be obtained by hydrolyzing an alkoxysilane compound and an imidosilane compound having a specific structure and then making the resulting hydrolysate undergo a condensation reaction. According to the present invention, it is possible to form a cured film excellent in adhesion. | 2010-12-16 |
20100316954 | MONOMER HAVING LACTONE SKELETON, POLYMER COMPOUND AND PHOTORESIST COMPOSITION - Disclosed is a novel monomer having a lactone skeleton, which is useful typically as a monomer component typically for a highly functional polymer, because, when the monomer is applied typically to a resist resin, the resin is satisfactory stable and resistant typically to chemicals, is highly soluble in organic solvents, and has improved hydrolyzability and/or water solubility after hydrolysis. | 2010-12-16 |
20100316955 | CHEMICALLY AMPLIFIED POSITIVE PHOTORESIST COMPOSITION AND PATTERN FORMING PROCESS - A polymer comprising a high proportion of aromatic ring structure-containing units and containing an aromatic sulfonic acid sulfonium salt on a side chain is used to form a chemically amplified positive photoresist composition which is effective in forming a resist pattern having high etch resistance. The polymer overcomes the problems of dissolution in solvents for polymerization and purification and in resist solvents. | 2010-12-16 |
20100316956 | PREPARING LITHOGRAPHIC PRINTING PLATES WITH ENHANCED CONTRAST - Lithographic printing plates can be prepared with enhanced contrast between the image and background by coloring the imaged or exposed regions using a coloring fluid containing a water-insoluble colorant (dye or pigment) and an organic solvent that swells the imaged regions sufficiently for the colorant to be embedded or diffused therein. | 2010-12-16 |
20100316957 | METHOD OF PRODUCING A RELIEF IMAGE ARRANGEMENT USABLE IN PARTICULAR IN THE FIELD OF FLEXOGRAPHY AND ARRANGEMENT PRODUCED ACCORDING TO THIS METHOD - The invention relates to a method of producing a relief image arrangement, usable especially in the fields of flexography, embossing and heliogravure, and comprising a base layer and a layer of photosensitive material fixed on the base layer. The method is of the type according to which an image is produced on the photosensitive layer by causing selective curing by irradiating the zones that are to be in relief with light of a predetermined wavelength. The method is characterized in that the image is produced in the form of a set of points to which a substantially pyramidal shape is given, widening out in the direction of the base layer ( | 2010-12-16 |
20100316958 | METHOD AND SYSTEM FOR CALIBRATING EXPOSURE SYSTEM FOR MANUFACTURING OF INTEGRATED CIRCUITS - Method and system for calibrating exposure system for manufacturing of integrated circuits. According to an embodiment, the present invention provides a method for determining one or more focus parameters for an exposure system. As an example, the exposure system is used for forming patterns on semiconductor wafer. The method includes a step for providing a semiconductor wafer. The semiconductor wafer is characterized by a diameter. The method also includes a step for forming a plurality of patterns using the exposure system on the semiconductor wafer. As an example, each of the plurality of patterns being associated with a focus reference value (e.g., focus distance, focus angle, etc.). The method additionally includes a step for determining a plurality of shift profiles, and each of the shift profile is associated one of the plurality of patterns. | 2010-12-16 |
20100316959 | METHODS FOR FORMING SHEETING WITH A COMPOSITE IMAGE THAT FLOATS AND A MASTER TOOLING - A sheeting and a method of forming a sheeting from a master tool are described where the sheeting has a composite image that floats above or below the sheeting. The method includes providing a first sheeting comprising a first array of microlenses and a photopolymerizable first material layer adjacent to the first array of microlenses. Another step is exposing the first sheeting to a radiation source to form a master tool comprising a plurality of polymerized first structured areas in the first material layer, wherein at least some of the first structured areas include a portion shape in common with at least some of the first structured areas and wherein each first structured area is associated with one of the first array of microlenses. Yet another step is replicating the plurality of first structured areas using a substance that conforms to the plurality of structured areas to form a second material layer having a plurality of replicated structured areas. | 2010-12-16 |
20100316960 | PATTERNING NANO-SCALE PATTERNS ON A FILM COMPRISING UNZIPPING POLYMER CHAINS - The invention concerns a method for patterning a surface of a material. A substrate having a polymer film thereon is provided. The polymer is a selectively reactive polymer (e.g. thermodynamically unstable): it is able to unzip upon suitable stimulation. A probe is used to create patterns on the film. During the patterning, the film is locally stimulated for unzipping polymer chains. Hence, a basic idea is to provide a stimulus to the polymeric material, which in turn spontaneously decomposes e.g. into volatile constituents. For example, the film is thermally stimulated in order to break a single bond in a polymer chain, which is sufficient to trigger the decomposition of the entire polymer chain. | 2010-12-16 |
20100316961 | SUBSTRATE TREATMENT METHOD AND SUBSTRATE TREATMENT APPARATUS - A substrate treatment apparatus which uniformly forms a fine resist pattern with a desired dimension within a plane of a substrate is disclosed. In a solvent vapor supply unit, a solvent vapor discharge nozzle is provided which can discharge a solvent vapor for swelling a resist pattern while moving above the front surface of a wafer. The wafer for which developing treatment has been finished and on which a resist pattern has been formed is carried into the solvent vapor supply unit, and the solvent vapor discharge nozzle is moved above the front surface of the wafer, so that the solvent vapor discharge nozzle supplies the solvent vapor onto the front surface of the wafer. This uniformly supplies a predetermined amount of solvent vapor to the resist pattern on the front surface of the wafer. As a result, the solvent vapor causes the resist pattern to evenly swell by a predetermined dimension, so that a resist pattern with a desired dimension is finally uniformly formed within the plane of the wafer. | 2010-12-16 |
20100316962 | Method for embodying an incense-coated template in variety of ornate and complex designs or patterns - A method of manufacturing an incense-coated template in a variety of ornate and complex designs or patterns is by cutting a template of the desired shape by hand or machine and coating the template with wood powder and aromatics. The template may be made from any of the options from the group consisting of bamboo paper, rice paper, papyrus paper, thin sheets of wood. The shape is then subjected to evenly-applied light coats of alternating water and wood powders, which form the incense coating. When desired thickness is reached, two final coats round out the process: one of powdered dye to attain the desired coloration, and one which comprises the application of an aromatic. The aromatic can be either scented oil or in a variation of powdered form, in which case the previously discussed setting and curing process of the wood powders would apply. | 2010-12-16 |
20100316963 | METHOD FOR PREVENTING COAGULATION IN EXHAUST PIPE OF BOILER - A method for preventing coagulation in an exhaust pipe of a boiler is provided. The method includes proportionally controlling combustion based on a quantity of supplied fuel with respect to an amount of air supplied to a burner, determining whether to enhance a heating power of a burner, based on a temperature of ambient air introduced into a blower, the temperature of the ambient air being sensed by an air temperature sensor, and enhancing the heating power of the burner to increase a temperature of exhaust gas, when it is determined that the sensed temperature is equal to or lower than a predetermined temperature. | 2010-12-16 |
20100316964 | SOLIDS FLOW METER FOR INTEGRATED BOILER CONTROL SYSTEM - A combustion control system [ | 2010-12-16 |
20100316965 | DEVICE AND METHOD FOR STABILIZING THE PRESSURE AND THE FLOW OF A GASEOUS MIXTURE SUPPLIED TO A SURFACE-COMBUSTION CYLINDRICAL BURNER - The invention relates to a gas burner comprising a perforated cylindrical wall used as a combustion surface, a bottom wall and an inlet opening through which a combustible gaseous mixture is fed inside the burner. The stabilisation device consists of a grid ( | 2010-12-16 |
20100316966 | Burner arrangement for a combustion system for combusting liquid fuels and method for operating such a burner arrangement - A burner arrangement for a combustion system for combusting liquid fuels including a burner hub, at least one air supply channel and at least one fuel supply channel for each fuel type is provided. The at least one fuel supply channel is embodied at least partially in the burner hub, with a flow divider arranged in at least one fuel supply channel, which is distanced from the wall of the fuel supply channel so that an interspace associated with the flow path of the fuel flowing through the fuel supply channel is formed between the wall of the fuel supply channel and the flow divider. A method for operating such a burner arrangement is also provided. | 2010-12-16 |
20100316967 | BURNER, SPECIFICALLY A PREMIX GAS BURNER - What is described is a burner, specifically for gas fuels with premixing, comprising a burner body designed to be housed in a combustion chamber of a heating apparatus, the burner body being provided with a burner head on which an air and gas mixture supplied to the combustion chamber is burnt, in which the burner head has a surface profile in the form of a dome-shaped spherical segment, the height of the dome being less than half of the diameter of the sphere to which the segment belongs. | 2010-12-16 |
20100316968 | METHOD OF OBJECT TRANSFER FOR A HEAT TREATMENT SYSTEM - Disclosed herein is method for use in a vertical heat treatment system which has an opening which is formed in a partition wall separating a housing-box transfer area from a treating-object transfer area (a wafer transfer area), and and through which an object to be treated is carried in the vertical heat treatment system to carry out a predetermined treatment. When the object to be treated is carried in via the opening of the partition wall, which separates the housing-box transfer area from the treating-object transfer area (wafer transfer area), to carry out a predetermined treatment, the structure of various mechanisms in the vicinity of the opening is simplified, and the space is saved. | 2010-12-16 |
20100316969 | Method of Heating a Mineral Feedstock in a Firing Furnace of the Tunnel Furnace Type - Method of heating a mineral feedstock in a firing furnace of the tunnel furnace type, having a hearth with an upstream inlet, a downstream outlet and sidewalls fitted with burners, in which method the feedstock is transported as a layer of approximately constant thickness along a treatment path in which the feedstock is heated and fired by means of said burners so as to obtain a fired product, said path being located between the upstream inlet and the downstream outlet of the furnace, characterized in that said burners comprise at least one fuel injector and at least one oxidizer injector and are positioned and oriented in such a way that their flames do not impact the layer, the at least one oxidizer injector being positioned relative to the at least one fuel injector so that the at least one fuel jet injected by the at least one fuel injector is separated from the layer by at least one oxidizer jet injected by at least one oxidizer injector. | 2010-12-16 |
20100316970 | Implant root for tooth implanting - An improved implant root for tooth implanting into the alveolar bone of a patient, said implant root comprises: a coarse threaded portion of the implant root is formed to have a wider base and to have an extension root with various radiant thread constructed, characterized with a circumferential constricted neck between these two segments. Both segments are designed to be seated into alveolar bone as implant root fixture. The widest diameter of the upper and lower segment is either equal or the lower base is slightly wider than lower segment for the most of it. The constricted neck in between the base and extension of the segments and the shape of the lower base segment allow the lower base implant root to serve as a primary stability anchor. Combining the concept of wider base with extensions allow the base segment of the implant fixture becomes a physiological anchor healed in bone and to increase the stability of the implant around the implant fixture after bone heal thus advantage the implant to be placed in some type of bones needing this kind of anchorage. | 2010-12-16 |
20100316971 | BONE-ADAPTIVE SURFACE STRUCTURE - The invention concerns bone-adaptive surface structures for lateral jaw implants. Micromechanical and/or macromechanical surface structures having various body forms are incorporated into selected segments of the surface of the base and of the bar that connects the threaded piece with the base to accelerate the healing process after the implant is inserted into the jaw bone and to make a critical improvement in holding the implant firmly in place without rotation. | 2010-12-16 |
20100316972 | METHOD FOR THE GENERATIVE PRODUCTION OF INDIVIDUAL DENTAL PREFORMED PARTS FOR ARTICULATORS - Method for the production of a denture comprising the following steps:—collection of the biometric data of a patient, namely, the toothed or untoothed mandible and maxilla, the sizing of the jaws, the spatial position thereof relative to the skull, the condyle inclination and the movement of the mandible, and the recording of the mandible movement;—implementation of the data in a virtual articulator which is made available in the main memory of the data processing equipment;—CAD construction of the individual articulator preformed parts and dental molded bodies based on the collected patient data;—production of the individual articulator molded bodies and dental molded bodies by means of a generative manufacturing process based on the recorded biometric data;—incorporation of the individual articulator preformed parts and/or dental molded bodies into a standardized articulator housing, or complete generative manufacture of the articulator with individualized molded bodies. | 2010-12-16 |
20100316973 | Apparatuses and Methods for Mandibular Protrusion - Embodiments of methods and mandibular protruders and positioning devices, comprising, for example: an upper mounting bracket having an upper dental appliance; a lower mounting bracket having a lower dental appliance; and a rail system configured to couple the upper mounting bracket to the lower mounting bracket. Some embodiments comprise a drive motor and/or an initial position adjustment mechanism. | 2010-12-16 |
20100316974 | METHOD OF MAKING A SURGICAL TEMPLATE USED FOR A COMPUTER-GUIDED DENTAL IMPLANT SURGERY - A method of making a surgical template comprises: producing a 3-D geometrical image by a CT scanning performed on a patient's jaw and establishing corresponding implant planning data to obtain a 3-D first digital image, making a positive plaster model of the patient's jaw, scanning the plaster model to obtain a 3-D second digital image, overlapping the second digital image on the first digital image to obtain a computer representation of the plaster model and at least one implant to be mounted according to the implant planning data, drilling the plaster model to form at least one pinhole according to the implant planning data, inserting a pin into the pinhole, producing a negative template body from an assembly of the plaster model and the pin with a thermoplastic dental material so that the negative template body has at least one implant guide hole and constitutes the surgical template. | 2010-12-16 |
20100316975 | Method And Device For Cleaning Teeth - The invention is directed to a method and a device for cleaning teeth wherein a variety of cleaning tools are coupled to a common handle section for the individual cleaning of teeth. It relates in particular to a handle section of an electric dental cleaning device, with a coupling section for coupling various cleaning tools thereto, as well as said cleaning tools. According to the invention the handle section detects a coding provided on the respective cleaning tool attached. In dependence upon the respective coding detected, various functions of the dental cleaning device are controlled. | 2010-12-16 |
20100316976 | METHOD FOR TEETH RESTORATION AND A TEETH MATRIX - A method for preparing a dental prosthesis, the method includes: selecting a tooth matrix out of a group of tooth matrices that differ from each other, wherein each tooth matrix comprises an inner cavity; wherein a tooth matrix is has an appearance of a tooth; and attaching at least a wall of the inner cavity of the tooth matrix to an intermediate element that is connected to the prosthesis core, remaining tooth structure or to the implant. | 2010-12-16 |
20100316977 | COUNTERMEASURE DEVELOPMENT METHOD AND SYSTEM - An architecture is provided for incorporating systems-thinking and cognitive psychology. A simulation nodule partners with a systemizing nodule to develop a solution (a countermeasure) a problem that an opponent could apply to injure the entity. Problem-defining, solution-developing, weakness-exposing, and/or solution-revising steps can be conceptualized from the opponent's viewpoint thanks to a role-reversing nodule, defensive theories can be tested by a combat-imitating nodule, and conclusions can be confirmed via a reality-checking nodule. | 2010-12-16 |
20100316978 | Mobile, wireless, hands-free visual/verbal trans-language communication system(acronym:V2V XLC System) - The V2V XLC system is a mobile, wireless trans-language communication (XLC) system enabling direct, real-time communications between people conversing in different languages, including visual (e.g. American Sign Language) and verbal (e.g. English) languages. The acronym “X-L-C” stands for Trans Language Communication. The FREEDOM XLC model enables Deaf and Hard of Hearing (DHH) users with real-time bidirectional communications capability to facilitate their interaction with the hearing society. A Freedom client using a Visual language (e.g. ASL) can converse directly with someone using a Verbal language (e.g. English) and vice versa. This is referred to as V2V communications. Equipped with wireless mobility, it is lightweight and “transparent”, providing anytime/anywhere availability. The Freedom features hands-free operation and multimedia interaction, including digital sign, video, synthesized voice and text. With cell phone size portability and direct access to wireless services, Freedom provides DHH users with an all-in-one P | 2010-12-16 |
20100316979 | DUMMY DEVICE, SYSTEM AND METHOD FOR PATIENT-BASED MEDICATION USING MEDICINAL AND/OR PHARMACEUTICAL AND/OR DIETARY SUPPLEMENT PRODUCTS FOR A PATIENT - The invention concerns a dummy device for patient-assisted medication with medical and/or pharmaceutical and/or food supplement products for a patient. The dummy device includes a pictorial representation, true to the original, of at least one real package detail containing the actual products. The dummy device is constructed and designed for interactive communication by at least one handling element. The invention further concerns a system using a dummy device and a method for patient-assisted control of medication with medical and/or pharmaceutical and/or food supplement products for a patient. | 2010-12-16 |
20100316980 | Foreign Language Teaching Method And Apparatus - Apparatus, method and software for teaching foreign language involving a data processing system having a program executing computer, a data storage device, and an output device; one or more data files containing written information in a user's native language, the written information being of current interest to the user; computer programs executing on the data processing system for: converting lexical blocks of said written information to a desired foreign language to create a mixed language written information; and displaying the mixed language written information on the output device. | 2010-12-16 |
20100316981 | Trigonometry teaching aid system - The present invention provides a teaching aid system ( | 2010-12-16 |
20100316982 | TIME-OUT DEVICE - A child time-out device ( | 2010-12-16 |
20100316983 | EDUCATIONAL EXERCISE SYSTEM AND METHOD SIMULATION OF SWORDPLAY - Provided herein is a role-playing sword-playing fitness-oriented educational system and method with physical game devices, as well as rules for their use. Players assume the roles of imaginary characters in a fictitious storyline and use sword devices and set value oriented tasks to progress through the game and achieve rewards and higher ranking as recognized in the domains of physical combat, magical forces, and technological abilities. The system and method integrates a fitness program, fantasy role-playing game, and martial arts into a personal development program for kids. Game apparatus are interactive padded swords that require physical interaction between players wherein through the demonstration of strategic and technological skills as well as achievement of value based skills the player achieve higher rankings and rewards. | 2010-12-16 |
20100316984 | DYNAMIC PULSE SIMULATOR - Embodiments of the present invention are directed to a system and method for generating a simulated pulse to be used in combination with a patient monitor. In many embodiments, a pulse is simulated by displacing a volume in a pressurized system. For instance, in one embodiment, the volume in the pressurized system is displaced by rotating a first end of a tube relative to a second end that is held stationary. A portion of the tube collapses due to the twisting causing the volume in the system to decrease. The first end of the tube may be rotated back to its original position causing the volume in the system to return to its original state. This change in volume simulates a pulse. | 2010-12-16 |
20100316985 | ASSESSABLE NATURAL INTERACTIONS IN FORMAL COURSE CURRICULUMS - A natural interactions academic course designer system and method that allows an educator to integrate a natural interactions forum (such as discussion boards, blogs, and collaborative wikis) into a formal curriculum. Embodiments of the system and method include a natural interactions integration module, which allows an educator to select a type of natural interaction forum and attaches a rubric, and a natural interactions provisioning module that creates the forum, determines the participants, and the learners to be assessed. Embodiments of the system and method also include an assessment module that assesses a validated learner using one or more of three different metrics. These metrics include a participation metric, a tagging metric, and a natural language processing metric. The assessment module then creates a raw score from the metrics used. Embodiments of the system and method also include a learner tracking module that generates a single final score for the assignment. | 2010-12-16 |
20100316986 | RUBRIC-BASED ASSESSMENT WITH PERSONALIZED LEARNING RECOMMENDATIONS - A rubric-based assessment and personalized learning recommendation system and method to aid an educator in teaching an entity in an efficient manner. Embodiments of the system and method include a computational representation of a rubric that is composed of composable rubric constructs. Each composable rubric construct corresponds to a particular sub-area of a skill being learned. Embodiments of the system and method also allow the educator to select a level of granularity of the rubric. This allows grouping together of entities that are having similar problems learning the skill and are performing similarly in certain areas. Embodiments of the system and method can suggest available learning resources for a single or groups of entities struggling in the same or similar areas based on their assessment results. The idea is for the entity to use these learning resources to improve its performance and competency in a given subject area. | 2010-12-16 |
20100316987 | EDUCATIONAL SERVICES AND CONTRACTS - Described is a technology in which an educational service provides contracts (an interface set) for calling functions that allow management of educational-related data. The interface set may be divided as interfaces to various services; roles associated with users of the educational service determine which interfaces/functions each user can call. The interfaces may include interfaces for calling course-related functions (e.g., of a course service), profile-related functions (e.g., of a profile service), membership-related functions (e.g., of a membership service) and task-related functions (e.g., of a task service). Other interfaces may include interfaces for calling plan-related functions, group-related functions, content-related functions, notification-related functions, provisioning-related functions, institution-related functions, department-related functions, utilities-related functions, standards-related functions, degree program-related functions, contextual communication-related functions and/or scoring related functions. | 2010-12-16 |
20100316988 | METHOD AND DEVICE FOR FILTERING PLATELETS - The present invention relates to methods for removing antiplatelet agents and anticoagulants from a platelet preparation. In one embodiment, the method includes the step of flowing the platelet preparation through a filtering tube comprising a filtering membrane and separating the antiplatelet agents and anticoagulants from the platelet preparation by tangential flow filtration. In another embodiment, the method includes the step of passing the platelet preparation through porous material that specifically binds to the antiplatelet agents and anticoagulants. | 2010-12-16 |
20100316989 | METHOD FOR SCREENING AN INHIBITORY AGENT OF HBV PROLIFERATION BY USING THE INTERACTION BETWEEN HBV CAPSID AND SURFACE PROTEINS BASED ON CELLULAR IMAGING - The present invention relates to a method for screening an inhibitory agent of HBV proliferation by measuring the interaction (binding strength) between capsid protein and surface protein, necessary for the proliferation of HBV, by using cellular imaging, more precisely a method for measuring changes on cellular imaging caused by the interaction between a fusion protein containing PreS domain of HBV surface protein and PH (Pleckstrin homology) domain sequence and a fusion protein containing capsid protein and fluorescence protein (GFP) interacting with the said fusion protein. The method of the present invention detecting the interaction between proteins necessary for HBV proliferation at cellular level can be effectively used for the screening of a novel inhibitory agent of HBV proliferation at cellular level. | 2010-12-16 |
20100316990 | Biomarkers for HPV-Induced Cancer - Biomarkers that correlate with progression to neoplasia in human papillomavirus (HPV) induced cancer, for example cervical cancer have been identified. These biomarkers can be used to diagnosis or assist in the diagnosis of HPV-induced cancer. They can also be used to increase the positive predictive value of current screening modalities. In addition, they can provide insights into the biology of HPV-induced cancer and thus provide leads for the development of nonsurgical therapies. Exemplary biomarkers include cornulin, PA28 β, DJ-1, actin, transthyretin, HSPB1, CV intracellular channel 1, cytokeratin 8, transferrin, Hsρβ6 (HSP20), aflatoxin reductase, α2 type I collagen, creatine kinase B, cytokeratin 13 GST π, PA28 α, Manganese SOD, lamin A/C, serpin B1 (elastase inhibitor), serpin B3 (SCAA1), cytokeratin 10, cytokeratin 6A, and trp-tRNA synthetase. Preferred biomarkers for HPV-induced cancer include cornulin, DJ-1, PA28 α, and PA28 β, trp-tRNA synthetase, HSPβ6, creatine kinase B, aflatoxin reductase, GST π, transthyretin, transferrin, α2-type 1 collagen, and combinations thereof. | 2010-12-16 |
20100316991 | HUMAN PARAINFLUENZA VIRUS TYPE 3 EXPRESSING THE ENHANCED GREEN FLUORESCENT PROTEIN FOR USE IN HIGH-THROUGHPUT ANTIVIRAL ASSAYS - Disclosed herein is a recombinant human parainfluenza virus expressing the enhanced green fluorescent protein. Methods of making and methods of using a recombinant human parainfluenza virus expressing the enhanced green fluorescent protein are also disclosed. A recombinant human parainfluenza virus expressing the enhanced green fluorescent protein was rescued and evaluated for its use in antiviral assays. Without limiting the invention, in one example, there is provided a cDNA clone of SEQ ID NO: 1. | 2010-12-16 |
20100316992 | DIAGNOSTIC TEST - Disclosed are methods for conducting diagnostic tests for the detection of the inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. Also described are methods for monitoring a patient by administering tests of the present invention. Also described are methods for monitoring patient's treatment by administering tests of the present invention. Also described are methods for evaluating the effectiveness of a drug or a drug candidate by administering tests of the present invention to samples from patients, animal models, and cell cultures treated with a drug or a drug candidate. Also disclosed are methods for determining the usefulness of analytes, e.g. cytokines, for acting as diagnostic and monitoring markers for inflammatory bowel disease in the various methods of the invention. | 2010-12-16 |
20100316993 | METHOD FOR ENRICHING A PROKARYOTIC DNA - A method is described for enriching procaryotic DNA, said method including the steps of contacting at least one procaryotic DNA with at least one protein or polypeptide which is capable of specifically binding to non-methylated CpG motifs, and separating the protein/polypeptide-DNA complex. Moreover, the application relates to a kit for carrying out said method. | 2010-12-16 |
20100316994 | DIAGNOSIS AND THERAPY OF CANCER USING SGP28-RELATED MOLECULES - The present invention relates to methods and compositions for the diagnosis and therapy of prostate cancer which utilize isolated polynucleotides corresponding to the human SGP28 gene, proteins encoded by the SGP28 gene and fragments thereof, and antibodies capable of specifically recognizing and binding to SGP28 proteins. | 2010-12-16 |
20100316995 | CONSENSUS CODING SEQUENCES OF HUMAN BREAST AND COLORECTAL CANCERS - Analysis of 13,023 genes in 11 breast and 11 colorectal cancers revealed that individual tumors accumulate an average of ˜90 mutant genes but that only a subset of these contribute to the neoplastic process. Using stringent criteria to delineate this subset, we identified 189 genes (average of 11 per tumor) that were mutated at significant frequency. The vast majority of these genes were not known to be genetically altered in tumors and are predicted to affect a wide range of cellular functions, including transcription, adhesion, and invasion. These data define the genetic landscape of two human cancer types, provide new targets for diagnostic and therapeutic intervention and monitoring. | 2010-12-16 |
20100316996 | Nasopharyngeal cancer malignancy biomarker and method thereof - The present invention discloses a nasopharyngeal cancer malignancy biomarker and a method thereof, wherein relative hnRNP K expression is used to evaluate the malignancy of nasopharyngeal cancer. The biomarker of the present invention assists the currently-existing inspections to find out cancer in the early stage and realize early diagnosis and early therapy. The present invention also functions as an effective indicator to monitor the metastasis and relapse of nasopharyngeal cancer. | 2010-12-16 |
20100316997 | Cell Markers for Human Embryonic Stem Cells - Polynucleotides associated with differentiation states of stem cells are provided. Also provided are methods and kits for detecting, identifying and/or discriminating differentiated stem cells from undifferentiated ones by measuring an expression level of one or more genes, such as CBARA1 and LHX 6, in the stem cells. | 2010-12-16 |
20100316998 | METHODS AND COMPOSITIONS FOR EMPIRICAL SELECTION OF DRUGS OR OTHER MOLECULES - Methods for identification and/or selection of species having activity for a target molecule are described, as well as related compounds. In some cases, the compounds and methods may be useful in a screening process, where species that exhibit a desired property or combination of properties are identified and isolated from a large library of species (e.g., 10 | 2010-12-16 |
20100316999 | Nucleic Acid Sequence Analysis - The present invention relates to a method for determining the sequence of a polynucleotide, the method comprising the steps of: (i) reacting a target polynucleotide with a polymerase enzyme immobilised on a solid support, and the different nucleotides, under conditions sufficient for the polymerase reaction; and (ii) detecting the incorporation of a specific nucleotide complementary to the target polynucleotide, by measuring radiation. | 2010-12-16 |
20100317000 | METHOD FOR DIAGNOSING BLADDER CANCER BY ANALYZING DNA METHYLATION PROFILES IN URINE SEDIMENTS AND ITS KIT - The present invention provides a method for detecting bladder cancer in a subject, comprising the following steps: (a) providing urine sediment sample from said subject; (b) determining methylation pattern of a given sequence within the promoter CpG islands of one or more genes (known as “gene” infra) in the samples; (c) comparing the methylation pattern from said subject with that from normal subject, wherein the hypermethylation of one or more of genes indicates that said subject is suffering from bladder cancer. The present invention also provides a kit for diagnosing bladder cancer. | 2010-12-16 |
20100317001 | METHOD OF USING TUMOUR RNA INTEGRITY TO MEASURE RESPONSE TO CHEMOTHERAPY IN CANCER PATIENTS - Cancerous tumours vary significantly in their response to chemotherapy agents. Currently, it is difficult to reliably assess the level of tumour responsiveness to a chemotherapy regimen during or post-administration. Biomarkers of tumour sensitivity to chemotherapy agents have hitherto been unknown. Such a biomarker would expedite identification of nonresponsive patients, who may then switch to other, possibly more effective regimens. The present invention provides a method for determining tumour responsiveness to a chemotherapy agent, wherein RNA is isolated from tumour cells of a patient before, during, and after chemotherapy. The quality of the RNA can be determined by capillary electrophoresis and assignment of an RNA integrity number (RIN). RIN values during and/or after chemotherapy are inversely proportionate to the level of tumour responsiveness. The tumour RIN is an easily accessed biomarker of tumour responsiveness to chemotherapy. The tumour RIN may also be used to assess the efficacy of a chemotherapy regimen. | 2010-12-16 |
20100317002 | METHODS AND KITS FOR DIAGNOSING LUNG CANCER - Provided is a method of identifying a genetically abnormal cell in a sputum sample, the method comprising: (a) staining a sputum sample using a morphological stain so as to identify a lower airway tract cell or lung cell in the sputum sample; and (b) staining the sputum sample using fluorescent in situ hybridization (FISH) so as to identify in the lower airway tract cell or lung cell a genetic abnormality in at least one of human chromosome 3p22.1 and 10q22-23, thereby identifying the genetically abnormal cell in the sputum sample. Also provided are methods and kits of diagnosing lung cancer by detecting a presence of genetically abnormal cells above a predetermined threshold in a sputum sample. | 2010-12-16 |
20100317003 | NOVEL COMPOSITIONS AND METHODS IN CANCER WITH ALTERED EXPRESSION OF KCNJ9 - The present invention relates to novel sequences for use in diagnosis and treatment of carcinomas, especially breast cancers. In addition, the present invention describes the use of novel compositions for use in screening methods. | 2010-12-16 |
20100317004 | PROBES - The present invention relates to probes, methods and apparatus for the detection of the presence or absence of non-contiguous cis-located nucleic acid sequences which are characteristic of alleles including those relating to the human leukocyte antigen (HLA) which is of interest in the field of human transplantation and disease. | 2010-12-16 |
20100317005 | Modified Nucleotides and Methods for Making and Use Same - Labeled nucleotide triphosphates are disclosed having a label bonded to the gamma phosphate of the nucleotide triphosphate. Methods for using the gamma phosphate labeled nucleotide are also disclosed where the gamma phosphate labeled nucleotide are used to attach the labeled gamma phosphate in a catalyzed (enzyme or man-made catalyst) reaction to a target biomolecule or to exchange a phosphate on a target biomolecule with a labeled gamme phosphate. Preferred target biomolecules are DNAs, RNAs, DNA/RNAs, PNA, polypeptide (e.g., proteins enzymes, protein, assemblages, etc.), sugars and polysaccharides or mixed biomolecules having two or more of DNAs, RNAs, DNA/RNAs, polypeptide, sugars and polysaccharides moieties. | 2010-12-16 |
20100317006 | SCA RISK STRATIFICATION BY PREDICTING PATIENT RESPONSE TO ANTI-ARRHYTHMICS - Genetic tests and methods for treatment based on markers to identify patients suffering from life-threatening ventricular tachy-arrhythmias, such as Ventricular Tachycardias (“VT”) and Ventricular Fibrillation (“VF”) that might lead to Sudden Cardiac Arrest (“SCA”) or Sudden Cardiac Death (“SCD”) are provided. Patients who cannot be sufficiently protected by medication alone, such as those refractory to anti-arrhythmic medication, are identified based on their genotype. The resulting information is used in a diagnostic test to identify and treat those patients who would benefit from the implantation of an Implantable Cardio Defibrillator (“ICD”). | 2010-12-16 |
20100317007 | Methods and Systems to Identify Operational Reaction Pathways - The present invention provides a method for identifying an operational reaction pathway of a biosystem. The method includes (a) providing a set of systemic reaction pathways through a reaction network representing said biosystem; (b) providing a set of phenomenological reaction pathways of said biosystem, and (c) comparing said set of systemic reaction pathways with said set of phenomenological reaction pathways, wherein a pathway common to said sets is an operational reaction pathway of said biosystem. Also described is a method of refining a biosystem reaction network; a method of reconciling biosystem data sets; a method of determining the effect of a genetic polymorphism on whole cell function; and a method of diagnosing a genetic polymorphism-mediated pathology. | 2010-12-16 |
20100317008 | Nonseparation Assay Methods - Assay methods are disclosed involving specific binding reactions which are simplified compared to known methods. A compound capable of producing chemiluminescence is immobilized on a solid support as is a member of a specific binding pair for capturing an analyte from a sample. An activator compound that activates the chemiluminescent compound and is conjugated to a specific binding pair member is added in excess along with the sample to the solid support. Addition of a trigger solution causes a chemiluminescent reaction at the sites where the activator conjugate has been specifically bound. The assay methods are termed non-separation assays because they do not require removal or separation of excess detection label (activator conjugate) prior to the detection step. The methods are applicable to various types of assays including immunoassays, receptor-ligand assays and nucleic acid hybridization assays. | 2010-12-16 |
20100317009 | Method for DNA Double-Strand Break Repair in Vitro and Applications Thereof - A system and a method for DNA double-strand break repair in vitro are disclosed. Applications of the disclosed method in multiple areas are also disclosed. | 2010-12-16 |
20100317010 | ELF3 gene compositions and methods - ELF3 gene compositions associated with cancer are provided, including ELF3 mRNA intron retention, a novel ELF3 5′ untranslated region, and a novel Alu, Alu | 2010-12-16 |
20100317011 | Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use - The invention relates to the molecule referred to as ALK-1, and its role as a type I receptor for members of the TGF-β family. The molecule has a role in the phosphorylation of Smad-5 and Smad1, which also act as activators of certain genes. Aspects of the invention relate to this interaction. | 2010-12-16 |
20100317012 | Massive parallel method for decoding DNA and RNA - This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue is incorporated into a growing strand of DNA in a polymerase reaction. The invention also provides nucleotide analogues which comprise unique labels attached to the nucleotide analogue through a cleavable linker, and a cleavable chemical group to cap the —OH group at the 3′-position of the deoxyribose. | 2010-12-16 |
20100317014 | COMPOSITIONS AND METHODS FOR THE ISOLATION OF NUCLEIC ACID - The present invention provides compositions and methods for the isolation of nucleic acids from a sample or subject. In particular, the present invention provides isolation, purification, and analysis of total DNA and RNA from a subject or sample. The compositions and methods find particular use in the isolation of nucleic acids associated with arthropods (e.g., ticks), including nucleic acid from pathogens carried by arthropods. | 2010-12-16 |
20100317015 | SPINOCEREBELLAR ATAXIA TYPE 8 AND METHODS OF DETECTION - The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided. | 2010-12-16 |
20100317016 | DYES AND LABELED MOLECULES - Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example. | 2010-12-16 |
20100317017 | CYSTIC FIBROSIS GENE MUTATIONS - The present invention provides novel mutations of the CFTR gene related to cystic fibrosis or to conditions associated with cystic fibrosis. Also provided are probes for detecting the mutant sequences. Methods of identifying if an individual has a genotype containing one or more mutations in the CFTR gene are further provided. | 2010-12-16 |
20100317018 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION - Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described. | 2010-12-16 |
20100317019 | NUCLEIC ACID DETECTION METHOD AND NUCLEIC ACID DETECTION KIT - The present invention is directed to a method with which one can detect a nucleic acid with sufficient accuracy, no matter the nucleotide length of a primer, and no matter if the analyte nucleotide consists of only a single nucleotide. Specifically disclosed is a method for detecting whether or not a nucleic acid sample contains a nucleic acid which has a target nucleotide sequence comprising one or more analyte nucleotide(s) in a nucleic acid sample. Firstly, in a step (a), a nucleic acid extension reaction is performed with use of a nucleic acid contained in the nucleic acid sample, an analyte nucleotide-identification primer, and a polymerase. Next, in a step (b), an extension product yielded from the step (a) is detected. The step (a) uses, as the primer, a polynucleotide which comprises a nucleotide sequence having an insertion site or a deletion site of one or more nucleotide(s), on the 5′ side of nucleotide(s) corresponding to the analyte nucleotide(s), in a nucleotide sequence homologous or complementary to an analyte nucleotide-containing partial region of the target nucleotide sequence. | 2010-12-16 |
20100317020 | METHODS AND COMPOSITIONS FOR DETECTING MICROORGANISMS - Methods of analyzing a sample for target microorganisms of interest are described. In particular, the methods are useful for detecting a variety of yeast and mold microorganisms based on the presence of a ubiquitous cell wall component, such as zymosan. Methods of analyzing a sample for fungal microorganisms using liposomes and/or culture media are also described. | 2010-12-16 |
20100317021 | FLUIDIC ANTIBODY-CONTAINING DEVICES AND METHODS - The invention relates to devices and methods for analyzing a sample (and preferably preparing a sample), which is particularly used in analysis, such as analysis of a sample for a bacterium of interest. | 2010-12-16 |
20100317022 | METHODS OF DIAGNOSING TISSUE FIBROSIS - The present invention provides a method of diagnosing the presence or severity of tissue fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissue inhibitor of metalloproteinases-1 (TIMP-1) in a sample from the individual; and diagnosing the presence or severity of tissue fibrosis in the individual based on the presence or level of α2-MG, HA and TIMP-1. | 2010-12-16 |
20100317023 | BIOCHEMICAL MARKERS FOR CVD RISK ASSESSMENT - A method of diagnosis of cardiovascular disease (CVD) an immunoassay to measure aggrecan fragments in said sample, and association of an elevation above a normal level with the presence of CVD, is conducted by contacting aggrecan fragments in said sample with an first antibody reactive with an N-terminal first epitope formed by cleavage of aggrecan by a proteinase and with a second antibody reactive with a second aggrecan epitope which is present in aggrecan at a location in the C-terminal direction from the location of said N-terminal epitope, and measuring the extent of simultaneous binding of both antibodies. | 2010-12-16 |
20100317024 | DERIVATIVES, REAGENTS, AND IMMUNOASSAY FOR DETECTING LEVETIRACETAM - Levetiracetam (LEV) derivatives, methods for synthesizing LEV derivatives, and immunodiagnostic assays for LEV. The synthesis methods described herein include chirally-selective, liquid-phase synthesis steps to produce selected LEV derivatives in high-yield. LEV derivatives can include operative groups, such as: immunogenic moieties that can be used to prepare anti-LEV antibodies; antigenic moieties that can be used in immunodiagnostic assays for LEV; or tracer moieties that can be used in immunodiagnostic assays. Additionally, the LEV derivatives can be used in immunodiagnostic assays to compete with LEV for anti-LEV antibodies. | 2010-12-16 |