50th week of 2011 patent applcation highlights part 39 |
Patent application number | Title | Published |
20110306489 | AMMONIA DECOMPOSITION CATALYST - Disclosed is an ammonia decomposition catalyst which is obtained by heat-treating a complex at a temperature of 360° C. to 900° C. in a reducing atmosphere, wherein the complex containing a polymer having a molecular weight of 1,000 to 500,000 represented by the formula [I], a transition metal coordinated with the polymer, and an activated carbon or a carbon nanotube added thereto. In a case of using the carbon nanotube, an alkali metal compound or an alkaline earth metal compound is added to the heat-treated complex. R | 2011-12-15 |
20110306490 | COMPOSITION OF SUPPORTED MOLYBDENUM CATALYST FOR SLURRY HYDROCRACKING - A composition is disclosed for converting heavy hydrocarbon feed into lighter hydrocarbon products. The heavy hydrocarbon feed is slurried with a catalyst comprising molybdenum supported on a base, such as boehmite or pseudo-boehmite alumina. Iron oxide may also be in the base. The base is preferably bauxite. The heavy hydrocarbon slurry is hydrocracked in the presence of the catalyst to produce lighter hydrocarbons. | 2011-12-15 |
20110306491 | Gulf oil spill underwater oleophilic hydrophobic oil-capturing water permeable drag-net - An underwater oleophilic hydrophobic oil-capturing water permeable drag-net with the porous oil-capturing water-repelling and water-permeable component positioned in the back of and connected to the drag-net that can be dragged vertically through the underwater oil spill area of the Gulf to remove oil is presented. The invention is made of various sizes depending on the area of the oil spill area; including 100 ft high (north to south), 100 ft wide (east to west) and 10 ft deep (front to back). The net mesh-like material is made from threads and wires knotted, twisted, and woven to form a regular pattern with fine spaces between the threads with each strand of a metal, plastic, wire and fiber net-type material made of and covered with organic and inorganic Oleophilic hydrophobic and superhydrophobic, oil attracting and oil bonding molecules, materials or sorbents including Superhydrophobic materials. The underwater drag-net collects large amounts of oil from the Gulf and reduces the negative impact of the Gulf oil spill on the Gulf and its shores. | 2011-12-15 |
20110306492 | ABSORBENT PRODUCT COMPRISING A MIXTURE OF A CATIONIC POLYSACCHARIDE AND A HYDROPHILIC CARRIER MATRIX - An absorbent product for feminine protection comprising a mixture of a cationic polysaccharide and a hydrophilic carrier matrix, wherein the cationic polysaccharide is a water-based cationic polysaccharide, and/or has a degree of cationization of less than 3% by weight. | 2011-12-15 |
20110306493 | Sulfoximinamide Compounds for Combating Animal Pests - The invention relates to sulfoximinamid compounds of formula (I), to the enantiomers, diastereomers and salts thereof and to compositions comprising such compounds. The invention also relates to the use of the sulfoximinamid compounds, of their salts or of compositions comprising them for combating animal pests. Furthermore the invention relates also to methods of applying such sulfoximine compounds. The sulfoximinamid compounds of the present invention are defined by the following formula I: wherein Q, Het, R | 2011-12-15 |
20110306494 | COMPOSITION BASED ON BACILLUS SPP. AND CORRELATE GENERA AND THEIR USE IN PEST CONTROL - The objective of the current invention is the control of agricultural infestations based on alternative methods that are less aggressive to the environment and that are harmless to other invertebrates and to man; for instance biological control using bacterial strains belonging to species of the genera | 2011-12-15 |
20110306495 | SELECTIVE HERBICIDES WITH ACTIVATOR ADJUVANTS - An environmentally compatible, selective herbicidal composition is provided that includes an activator adjuvant for enhancing the efficacy of the composition. While the activator adjuvant can be used in combination with a variety of herbicides, in an exemplary embodiment the herbicidal composition includes a metal chelate that is formed from a transition metal component and at least one chelating agent. The activator adjuvant can enhance, even synergistically effect the efficacy of the composition, while maintaining the selectivity of the herbicide. | 2011-12-15 |
20110306496 | USE OF 5-BENZYLOXYMETHYL-1,2-ISOXAZOLINE DERIVATIVES AS A HERBICIDE - A method of selectively controlling annual bluegrass and/or goosegrass in turf grass, the method includes applying 5-benzyloxymethyl-1,2-isoxazoline derivative compounds, pre-emergence or post-emergence, to goosegrass and/or annual bluegrass in turf grass. | 2011-12-15 |
20110306497 | TURFGRASS QUALITY - The present invention relates to a method for improving turfgrass quality, by applying to the turfgrass a plant growth regulator and jasmonic acid, or a salt or ester thereof, and to a composition comprising the same. | 2011-12-15 |
20110306498 | METHOD OF RESTORING MALE STERILITY IN GRAMINEOUS PLANTS AND MALE STERILITY RESTORATIVE AGENT - The present invention provides a method and a composition for restoring pollen fertility by suppressing formation insufficiency in a pollen formation process due to a high-temperature or low-temperature stress. The present invention provides a fertility restorative agent comprising an auxin as an active ingredient, and a method for restoring the fertility of a plants of the family Poaceae, comprising spreading an auxin. Moreover, the present invention provides a fertility restorative agent containing as an active ingredient a substance which inhibits auxin action, and a method for restoring the fertility of rice plant, including spreading a substance which inhibits auxin action. Preferably, the auxin is 10 | 2011-12-15 |
20110306499 | Biphenyl-Substituted Spirocyclic Ketoenols - The invention relates to novel compounds of the formula (I) | 2011-12-15 |
20110306500 | Method of Treating a Material Using a Sol-gel Derived Composition - Disclosed is a method and system that includes treating a material by applying a sol-gel derived composition loaded with a first sorbate under conditions effective to treat the material with the first sorbate. | 2011-12-15 |
20110306501 | ACTIVE INGREDIENT-COMPRISING MICROCAPSULES WITH A METAL OXIDE-CONTAINING SHELL - The present invention relates to microcapsules with a core/shell structure which comprise at least one low molecular weight, anionic surfactant and have a metal oxide-containing shell, to a process for producing such microcapsules with a core/shell structure, to the use of the microcapsules with the core/shell structure and to preparations comprising the microcapsules with the core/shell structure. | 2011-12-15 |
20110306502 | Novel Water Dispersible Granular Composition - A water dispersible granular composition comprising: at least one solid agrochemically active substance; at least one sorptive filler; at least one first agrochemically acceptable excipient; at least one liquid or low melting agrochemically active substance; and, at least one second agrochemically acceptable excipient. The invention further relates to a process of preparing the water dispersible granular composition. | 2011-12-15 |
20110306503 | TEMPLATE-DEPENDENT NUCLEIC ACID POLYMERIZATION USING OLIGONUCLEOTIDE TRIPHOSPHATES BUILDING BLOCKS - A novel use of a template-dependent polymerase. The novel use is effected by employing the template-dependent polymerase for incorporating at least one oligonucleotide triphosphate onto a nascent oligonucleotide-3′-OH in a template-dependent manner. | 2011-12-15 |
20110306504 | POLYNUCLEOTIDE MAPPING AND SEQUENCING - The present invention provides methods of obtaining structural information about a biopolymer sample. The methods include labeling portions of a biopolymer, such as DNA or RNA, linearizing the biopolymer in some cases, and determining the distance between the labels. The user can then compare different samples' between-label distances to qualitatively compare different samples and to assay a given sample for additions or deletions of nucleotides in the regions flanked by the labels. The methods also permit sequencing of biopolymers. | 2011-12-15 |
20110306505 | X-STR multiplex PCR amplification system - The methods and compositions provided herein relate to the discovery of several new STR alleles and a 20-plex multiplex assay for markers found on the human X chromosome. These X-STR markers have been found when used in a multiplex reaction to provide higher discriminatory power when compared to existing X-STR assay kits available commercially. Embodiments of the present teachings include methods for allelic determination of X-STR markers, amplification primers for the analysis of X-STR markers in a multiplex reaction, allelic ladders for analysis of X-STR markers, and kits for the analysis of X-STR markers. | 2011-12-15 |
20110306506 | ASSAY DEVICE AND METHOD FOR PERFORMING BIOLOGICAL ASSAYS - The invention provides a multiplexed assay device comprising a reaction chamber and several sets of encoded microcarriers | 2011-12-15 |
20110306507 | METHOD AND TOOLS FOR PROGNOSIS OF CANCER IN HER2+PARTIENTS - A gene or protein set includes at least 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, and possibly 40, 45, 50, 55, 60, 65 genes or proteins, antibodies or hypervariable portion thereof directed against the proteins encoded by these genes. | 2011-12-15 |
20110306508 | Method of Mycotoxin Detection - The presence of mycotoxins in agricultural products necessitates large scale testing of a wide range of sample material to ensure the safety of food and feed. The mycotoxin ochratoxin A represents an enablement for all mycotoxins as the level of sensitivity necessary for regulatory requirements for this compound at the part per billion level are as low or lower than any other mycotoxin. This invention describes the identification of a set of DNA ligands with sufficiently high binding affinity and specificity for ochratoxin A to enable an improvement over existing methods for the separation, concentration and quantitative determination of ochratoxin A in sample material. | 2011-12-15 |
20110306509 | COMPOSITIONS AND METHODS FOR THE IDENTIFICATION OF INHIBITORS OF PROTEIN SYNTHESIS - Compositions and methods for identifying inhibitors of RNA-target molecule interactions are provided as well as identifying inhibitors that block the role of tRNA in protein synthesis. The methods involve forming a mixture comprising a tRNA fragment molecule containing a modified nucleotide, a target molecule capable of binding to the tRNA fragment, and a test compound. The mixture is incubated under conditions that allow binding of the tRNA and the target molecule in the absence of the test compound. Assays can then be performed that detect whether or not the test compound inhibits the binding of the tRNA molecule and the target molecule. High throughput assays are also provided. | 2011-12-15 |
20110306510 | OPTIMIZED PPROBES AND PRIMERS AND METHODS OF USING SAME FOR THE DETECTION, SCREENING, ISOLATING AND SEQUENCING OF MRSA, MSSA STAPHYLOCOCCUS MARKERS, AND THE ANTIBIOTIC RESISTANCE GENE MEC A - Described herein are primers and probes useful for the detection, screening, isolation and sequencing of MRSA, MSSA, | 2011-12-15 |
20110306511 | METHODS FOR MULTIPLEX ANALYTE DETECTION AND QUANTIFICATION - The application refers to a method for detecting and quantifying multiple target analytes in a test sample using a single reaction vessel. The method uses a reaction vessel (a multi-well plate), which comprises a microarray of: (a) calibration spots, each having a predetermined quantity of the target analyte; and (b) capture spots, each having an agent (antibody) that selectively binds the target analyte. The captured analytes and the calibration spots are detected with fluorescently labelled antibodies specific for each different target analyte. The calibration spots are used to generate calibration curves that allow the measurement of the concentration of the different target analytes. The application also refers to a method for detecting and quantifying biomarkers that are useful for diagnosing rheumatoid arthritis. More specifically, the application discloses the use of rheumatoid factor (RF) and cyclic citrullinated peptide (CCP), as capture spots. Finally, based on the above method, it is proposed a method for diagnosing or monitoring rheumatoid arthritis. | 2011-12-15 |
20110306512 | Gene Expression Profiling for Identification, Monitoring, and Treatment of Osteoarthritis - A method is provided in various embodiments for determining a profile data set for a subject with osteoarthritis or conditions related to osteoarthritis based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least one constituent from Tables 1-2, 4-6, and 8. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable. | 2011-12-15 |
20110306513 | NOVEL BIOMARKER FOR LIVER CANCER AND APPLICATIONS FOR SAME - The present invention relates to the elucidation of a gene that can act as a novel marker for liver cancer diagnosis and to diagnostic and prognostic measurements of liver cancer using the same. More specifically, it relates to a diagnosis kit that enables diagnostic and prognostic measurement of a liver cancer using a preparation that measures expression levels of at least one gene selected from a group of liver cancer diagnosis markers consisting of S100P, NK4, CCL20, CSPG2, PLAU, MMP12, ESM-1, ABHD7, HCAPG, CXCL-3, Col5A2, MAGEA, GSN, CDC2, CST1, MELK, ATAD2, FAP and MSN and/or a method for diagnostic and prognostic measurement of liver cancer using the same. These have been discovered using normal liver tissues and liver cancer tissues collected from the same liver cancer patient of the present invention and represent the markers whose accuracy and reliability have been greatly improved as markers of liver cancer. The markers of the present invention can be used for the accurate diagnosis and prognosis of liver cancer. | 2011-12-15 |
20110306514 | RATIO BASED BIOMARKERS AND METHODS OF USE THEREOF - Compositions, methods and kits are described for identifying biomolecules (e.g., proteins and nucleic acids) expressed in a biological sample that are associated with the presence, development, or progression of a disease (such as cancer), or more generally determination of the etiology or risk factors associated with a disease. Sample types analyzed by the disclosed methods include but are not limited to archival tissue blocks that have been preserved in a fixative, tissue biopsy samples, tissue microarrays, and so forth. The methods disclosed herein correlate expression profiles of biomolecules with various disease types, and allow for the determination of relative survival rates; in some embodiments, the methods permit determination of survival rates for a subject with cancer. In other embodiments, the disclosure relates to methods for evaluating therapeutic regimes for the treatment, such as treatment of cancer. | 2011-12-15 |
20110306515 | DEVICE FOR SEROLOGICALLY DETECTING YERSINIA INFECTIONS AND/OR SECONDARY DISEASES THEREOF AND USE OF THE PROTEINS MyfA AND PsaA OF Y. ENTEROCOLITICA AND Y. PSEUDOTUBERCULOSIS AS RECOMBINANT ANTIGENS - Devices are disclosed for serologically detecting an infection with human-pathogenic | 2011-12-15 |
20110306516 | METHODS FOR PRODUCING INDUCED PLURIPOTENT STEM CELLS - The invention provides improved methods for producing induced pluripotent stem cells (iPSC) from adult fibroblasts. The methods include contacting adult fibroblasts with a reprogramming composition suitable for reprogramming the adult fibroblasts to iPSC, under conditions effective for the reprogramming composition to penetrate the adult fibroblasts, followed by culturing the contacted fibroblasts for a time period sufficient for the cells to be reprogrammed. The cultured cells are then sorted to select cells based upon their expression of the cell membrane surface markers CD13 | 2011-12-15 |
20110306517 | REDUCING IRF4, DUSP22, OR FLJ43663 POLYPEPTIDE EXPRESSION - This document relates to the activity of interferon regulatory factor 4 (IRF4) in T-cell lymphomas. For example, methods and materials involved in reducing the expression of an IRF4 polypeptide in T-cell lymphoma cells and identifying agents having the ability to reduce expression of an IRF4 polypeptide in T-cell lymphoma cells are provided. This document also relates to reducing DUSP22 or FLJ43663 polypeptide activity in T-cell lymphomas. For example, methods and materials involved in reducing the expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells and identifying agents having the ability to reduce expression of DUSP22 polypeptides and/or FLJ43663 polypeptides in T-cell lymphoma cells are provided. | 2011-12-15 |
20110306518 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION - Methods of diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection, in a patient by detecting the expression level of one or more genes in a patient, are described. Diagnostic oligonucleotides for diagnosing or monitoring transplant rejection, particularly cardiac transplant rejection and kits or systems containing the same are also described. | 2011-12-15 |
20110306519 | METHOD OF FORMING POLYMERIC MICROARRAY SUPPORT - In combination, a polymeric microarray support for an optical assay arrangement, that includes an optical detection instrument having a known depth of focus for detecting light emitted from said microarray support. The polymeric microarray support has a support surface made from a polymeric support material having a thickness varying over the area of the support surface by a thickness variation value. The said support includes formed microfeatures made up of grooves arranged to have a predetermined depth at the time of forming, the groove depth being selected based on the depth of focus of the optical detection instrument and the thickness of the support. The sum of the depth for the grooves and the thickness variation value of the polymeric support surface substantially corresponds to the depth of focus of the optical detection instrument in order to reduce noise, the polymeric support surface having attached thereto probe molecules to form binding sites. | 2011-12-15 |
20110306520 | Methods, Kits and Compositions Pertaining to the Suppression of the Detectable Probe Binding to Randomly Distributed Repeat Sequences Genomic Nucleic Acid - This invention is directed to methods, kits, non-nucleotide probes as well as other compositions pertaining to the suppression of binding of detectable nucleic acid probes to undesired nucleotide sequences of genomic nucleic acid in assays designed to determine target genomic nucleic acid. | 2011-12-15 |
20110306521 | SEPARATION OF PYROPHOSPHATE RELEASE AND PYROPHOSPHATE DETECTION - The present technology relates to methods and systems for detection of pyrophosphate. As such, disclosed herein are methods and systems that permit improved pyrophosphate detection. Also disclosed herein are methods and systems which utilize improved pyrophosphate detection for nucleotide sequencing. | 2011-12-15 |
20110306522 | MICROFLUIDIC PROTEIN CRYSTALLOGRAPHY - The use of microfluidic structures enables high throughput screening of protein crystallization. In one embodiment, an integrated combinatoric mixing chip allows for precise metering of reagents to rapidly create a large number of potential crystallization conditions, with possible crystal formations observed on chip. In an alternative embodiment, the microfluidic structures may be utilized to explore phase space conditions of a particular protein crystallizing agent combination, thereby identifying promising conditions and allowing for subsequent focused attempts to obtain crystal growth. | 2011-12-15 |
20110306523 | Polyamide Emulsifier Based on Polyamines and Fatty Acid/Carboxylic Acid for Oil Based Drilling Fluid Applications - The present invention generally relates to emulsifiers for oil-based drilling fluids and muds comprising an emulsifier based on the polyamides derived from fatty acid/carboxylic acid and optionally alkoxylated polyamines. The invention also relates to oil or synthetic based drilling fluids comprising the emulsifiers of the invention and to drilling methods utilizing same. | 2011-12-15 |
20110306524 | DRILLING FLUID AND METHODS - A drilling fluid comprising: a non-ionic surfactant including: a branched alcohol ethoxylate and/or a capped alcohol ethoxylate; and a detergent builder. | 2011-12-15 |
20110306525 | AQUEOUS DISPLACEMENT FLUID INJECTION FOR ENHANCING OIL RECOVERY FROM AN OIL BEARING FORMATION - A method for enhancing recovery of crude oil from a porous subterranean formation of which the pore spaces contain crude oil and connate water comprises:—determining the Ionic Strength (Mol/l) of the connate water; and—injecting an aqueous displacement fluid having a lower Ionic Strength (Mol/l) than the connate water into the formation, which aqueous displacement fluid furthermore has an Ionic Strength below 0.15 Mol/l. FIGS. | 2011-12-15 |
20110306526 | LUBRICATING OIL BASED ON POLYOL ESTERS - The present invention relates to oils based on polyol esters, which may be obtained from renewable resources and used as lubricant bases or lubrication additives, notably in four-stroke engine oils, oils for hydraulics or transmissions, as well as industrial lubricants. | 2011-12-15 |
20110306527 | GREASE COMPOSITION - The disclosure relates to a grease composition comprising:
| 2011-12-15 |
20110306528 | Lubricating Composition Containing a Functionalised Carboxylic Polymer - The invention provides a lubricating composition comprising an oil of lubricating viscosity and an amine-functionalised additive, wherein the amine-functionalised additive is derived from an amine having at least 3 aromatic groups, at least one —NH2 functional group, and at least 2 secondary or tertiary amino groups. The invention further provides for the additive to have dispersant and/or dispersant viscosity modifying properties. The lubricating composition is suitable for lubricating an internal combustion engine. | 2011-12-15 |
20110306529 | Star Polymer Lubricating Composition - The invention provides a lubricating composition containing (a) 0.001 to 15 wt % of a polymer with (i) a weight average molecular weight of 50,000 to 1,000,000; and (ii) a shear stability index of 10 to 100; (b) an antiwear agent; (c) a corrosion inhibitor; and (d) an oil of lubricating viscosity. The invention further provides a method for lubricating a mechanical device with the lubricating composition. | 2011-12-15 |
20110306530 | CONTINUOUSLY VARIABLE TRANSMISSION OIL COMPOSITION - Provided is a continuously variable transmission oil composition that can markedly increase the coefficient of friction between a metal belt or a chain and a pulley, that can maintain the high coefficient of friction over a long period of time, and that causes no clogging of the clutch plate. The continuously variable transmission oil composition includes 0.005-0.15 mass %, as phosphorous compound-derived phosphorus content with respect to the total amount of the composition, of at least one type of phosphorous compound represented by general formula (1) in a lubricating oil base. (1) In general formula (1), R | 2011-12-15 |
20110306531 | ETHER POLYSULFIDES AND POLYETHER POLYSULFIDES, THEIR PREPARATION AND USE - Novel sulfur-containing compositions comprise a polyether polysulfide or an ether polysulfide. The polyether polysulfide may be based upon an alkoxylate (an alcohol or glycol-initiated compound) that is a copolymer of at least two of ethylene oxide, propylene oxide and butylene oxide. The polyether polysulfide may alternatively be based upon a homopolymer of ethylene oxide, propylene oxide or butylene oxide. The ether polysulfide may be based upon a methoxy-capped polyglycol or an alkyl ether of 1,3-dichloro-2-propanol. | 2011-12-15 |
20110306532 | REFRIGERATOR OIL - Provided is a refrigerating machine oil which contains a base oil mainly containing at least one substance selected from the group consisting of a mineral oil, a synthetic alicyclic hydrocarbon compound, and a synthetic aromatic hydrocarbon compound and having a kinematic viscosity at 40° C. of 1 to 8 mm | 2011-12-15 |
20110306533 | USE OF COMB POLYMERS AS ANTIFATIGUE ADDITIVES - The invention relates to the use of comb polymers comprising repeating units in the main chain which repeating units are derived from polyolefin-based macromonomers having a molecular weight of at least 500 g/mol, and repeating units which are derived from low-molecular monomers having a molecular weight of less than 500 g/mol as antifatigue additives in lubricants. The invention further relates to novel comb polymers and methods for the production thereof and to lubricating oils comprising said comb polymers. | 2011-12-15 |
20110306534 | MULTIPURPOSE ACIDIC, ORGANIC SOLVENT BASED MICROELECTRONIC CLEANING COMPOSITION - A cleaning composition for cleaning microelectronic or nanoelectronic devices, the cleaning composition having HF as the sole acid and sole fluoride compound in the composition, at least one primary solvent selected from the group consisting of sulfones and selenones, at least one polyhydroxyl alkyl or aryl alcohol co-solvent having metal ion complexing or binding sites, and water, and optionally at least one phosphonic acid corrosion inhibitor compound and the is free of amines, bases and other salts. | 2011-12-15 |
20110306535 | Composition with UV protectant for restoration and preservation of PVC products - A composition for restoration and treatment of PVC materials is provided and the composition comprises: at least one plant based solvent; and at least one UV protectant, and the plant based solvent comprises from about 20% to about 95% of said composition and the UV protectant is from about 1% to about 15% of said composition. | 2011-12-15 |
20110306536 | Compacted Liquid Laundry Detergent Composition Comprising Lipase of Bacterial Origin - A liquid laundry detergent composition including: (i) detersive surfactant including anionic detersive surfactant and optionally non-ionic surfactant, optionally wherein the weight ratio of anionic detersive surfactant to non-ionic detersive surfactant is greater than 1:1; (ii) optionally, surfactancy boosting polymer; (iii) from 0 wt % to 10 wt % fatty acid; (iv) optionally, silicone suds suppressor; (v) optionally, structurant; (vi) lipase of bacterial origin; and (vii) optionally nil-boron enzyme stabilizer; wherein the electrolytic strength of the composition at a concentration of 1 g/l in de-ionized water and at a temperature of 25° C. in mScm | 2011-12-15 |
20110306537 | Solid Detergent Composition Comprising Lipase of Bacterial Origin - A solid detergent composition including: (a) detersive surfactant; (b) lipase of bacterial origin; (c) from 0 wt % to less than 10 wt % zeolite builder; (d) from 0 wt % to less than 10% phosphate builder; (e) optionally, from 0 wt % to less than 10 wt % silicate; and (f) optionally perfume; and (g) optionally, additional detergent ingredients. | 2011-12-15 |
20110306538 | FRAGRANCE COMPOSITIONS - Provided is a fragrance composition having a natural rose aroma with freshness, sweetness, and softness, which is hardly reproduced by combining aroma components conventionally known as rose aromas. Also provided is a fragrance composition having excellent rose-like naturalness, freshness, and richness. More specifically, provided are: a fragrance composition, having added thereto 2-isopropyl-4-methylthiazole alone or in combination with rose oxide; a method of manufacturing the same; and a method of imparting an aroma to a fragrance composition, the method including adding 2-isopropyl-4-methylthiazole to a base fragrance composition having a rose-like aroma as a main aroma. Also provided are: a rose-like fragrance composition, having added thereto methyl epijasmonate alone or in combination with 2-isopropyl-4-methylthiazole; a method of manufacturing the same; and a method of imparting an aroma to a fragrance composition, the method including adding methyl epijasmonate alone or in combination with 2-isopropyl-4-methylthiazole to a base fragrance composition having a rose-like aroma as a main aroma. | 2011-12-15 |
20110306539 | PROCESS FOR MAKING PARTICLES FOR DELIVERY OF DRUG NANOPARTICLES - A process for making particles for delivery of drug nanoparticles is disclosed herein. The process comprises the steps of (a) forming a suspension of drug nanoparticles by mixing a precipitant solution with an anti-solvent solution under micro-mixing environment, where the formed nanoparticles have a narrow particle size distribution; (b) providing an excipient to at least one of the precipitant solution, the anti-solvent solution and the suspension of drug nanoparticles, the excipient being selected to maintain said drug nanoparticles in a dispersed state when in liquid form; and (c) drying the suspension of drug nanoparticles containing the excipient therein to remove solvent therefrom, wherein removal of the solvent causes the excipient to solidify and thereby form micro-sized matrix particles, each micro-sized particle being comprised of drug nanoparticles dispersed in a solid matrix of the excipient. | 2011-12-15 |
20110306540 | Use of Leptin for Treating Human Lipoatrophy and Method of Determining Predisposition to Said Treatment - Leptin, leptin analogs, and leptin derivatives are used to treat patients with lipoatrophy. Leptin is effective against conditions of lipoatrophy for both genetic and acquired forms of the disease. A therapeutically effective amount of leptin can be administered in a variety of ways, including subcutaneously and using gene therapy methods. Methods of the present invention contemplate administration of leptin, leptin analogs, and leptin derivatives to patients having a leptin level of approximately 4 ng/ml or less before treatment. | 2011-12-15 |
20110306541 | METHODS FOR TREATING HCV - This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions. | 2011-12-15 |
20110306542 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS - Compounds that bind the glucagon-like peptide 1 receptor (GLP-1) receptor are provided including compounds which are modulators of the GLP-1 receptors and compounds which are capable of inducing a stabilizing effect on the receptor for use in structural analyses of the GLP-1 receptor. Methods of synthesis, methods of therapeutic and/or prophylactic use, and methods of use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor of such compounds are provided. | 2011-12-15 |
20110306543 | COMBINATION OF INSULIN WITH TRIAZINE DERIVATIVES AND ITS USE FOR TREATING DIABETES - The invention relates to a composition for use as a medicament comprising insulin in combination with at least one compound of formula (I) | 2011-12-15 |
20110306544 | METHODS AND FORMULATIONS FOR INCREASING INTESTINAL FUNCTION - A method for increasing intestinal function is provided. The method comprising orally and/or enterally administering to a subject in need thereof a therapeutically effective amount of insulin, thereby increasing intestinal function. | 2011-12-15 |
20110306545 | NOVEL PEPTIDES FOR WOUND HEALING - The present invention relates to new peptides, pharmaceutical composition and cosmetic composition including them and their use for wound healing. | 2011-12-15 |
20110306546 | COMPOSITIONS FOR INCREASING HAIR GROWTH AND DECREASING HAIR LOSS - The invention provides compositions and methods for increasing hair growth and decreasing hair loss. In one embodiment, the compositions comprise a plurality of hair growth agents. Optionally, the hair growth agents are selected from the group consisting of: IGF-1, FGF-2, FGF-10, PDGF-AA, Wnt-3a, noggin, ephrin-A3, sonic hedgehog (SHH), BMP-6 and hypoxanthine. | 2011-12-15 |
20110306547 | LHRH - ANTAGONISTS IN THE TREATMENT OF FERTILITY DISORDERS - A method of treating infertility disorders by 1) administering an LH-RH antagonist, preferably Cetrorelix, in amounts to selectively suppress endogenous LH but not FSH secretion and 2) inducing follicle growth by administration of exogenous gonadotropin. The selective suppression OF LH allows FSH secretion to be at natural level S thereby not affecting individual estrogen development. The LH-RH antagonist can be given as a single or dual subcutaneous dose in the range of 1 mg to 10 mg, preferably 2 mg-6 mg. In multiple dosing posology, LH-RH antagonist can be administered subcutaneously in an amount in the range of 0.1 to 0.5 mg of LH-RH antagonist/day . LH-RH antagonist is applied starting cycle day 1 to 10, preferably on day 4 to 8, and ovulation can be induced between day 9 and 20 of the menstruation cycle by administering rec. LH, native LH-RH, LH-RH agonist or by HCG. In addition rec. LH, native LH-RH or LH-RH agonist can be given to avoid hyperstimulation syndrome and native LH-RH or a LH-RH agonist can be administered to avoid luteal phase stimulation by neutralising the negative effects of HCG. | 2011-12-15 |
20110306548 | STABLE GROWTH HORMONE COMPOUNDS - The present invention relates to stable growth hormone (GH) compounds, which through the introduction of cysteine residues have disulphide bridges, which make the compounds resistant to proteolytic degradation. | 2011-12-15 |
20110306549 | GLP-1 RECEPTOR AGONISTS TO TREAT PANCREATITIS - The disclosure provides the use of GLP-1 receptor agonist compounds to treat pancreatitis (e.g., acute, chronic, hemorrhagic, necrotizing) in patients. The disclosure also provides the use of GLP-1 receptor agonist compounds to reduce elevated plasma amylase and/or lipase concentrations in patients. An exemplary GLP-1 receptor agonist compound is exenatide. | 2011-12-15 |
20110306550 | APOE ANALOGS AND METHODS FOR THEIR USE - Novel ApoE peptide derivatives and ApoE-protein transduction domain conjugates are disclosed which are useful for treating disorders including CNS inflammation, traumatic brain injury, inflammatory bowel disease (also known as Crohn's Disease or ulcerative colitis), cerebral ischemia, atherosclerosis, sepsis, multiple sclerosis and arthritic diseases, Alzheimer's Disease and other brain disorders. The invention encompasses methods for protecting subjects having undergone irradiation or radiotherapy by administration of ApoE or at least one ApoE mimetic peptide. | 2011-12-15 |
20110306551 | Modification of Factor VIII - A Factor VIII derivative of formula (I): wherein: B represents C | 2011-12-15 |
20110306552 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 - The present invention relates to new pyrimidinone inhibitors of lipoprotein-associated phospholipase A2 activity, pharmaceutical compositions thereof, and methods of use thereof | 2011-12-15 |
20110306553 | METHODS AND USES INVOLVING HEME BINDING PROTEIN 1 - The present invention relates to a method of screening for a modulator of endothelial NO synthase (eNOS) expression, a method of diagnosing a cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament for preventing and/or treating a disease involving eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of eNOS signal transduction, and the use of HEBP1 for the regulation of eNOS promoter activity. | 2011-12-15 |
20110306554 | PEPTIDE CAPABLE OF BINDING TO IMMUNOGLOBULIN - The present invention provides a peptide capable of binding to an immunoglobulin, a fusion protein with the peptide, nucleic acids coding for the peptide and for the fusion protein, methods for producing the peptide and the fusion protein, and a composition and means for binding an immunoglobulin, as well as a pharmaceutical composition for the treatment or prevention of a disease caused by the binding between C1q and an immunoglobulin, which includes a peptide capable of binding to the immunoglobulin or a fusion protein with the peptide, and others. | 2011-12-15 |
20110306555 | BIOLOGIC REPLACEMENT FOR FIBRIN CLOT - The invention provides composition and methods for repairing a ruptured anterior cruciate ligament. | 2011-12-15 |
20110306556 | NEUROPROTECTION FROM BRAIN ANOXIA AND REPERFUSION INJURY DURING STROKE AND COMPOSITIONS OF PKG PATHWAY ACTIVATORS AND METHOD OF USE THEREOF - A pharmaceutical composition for treating or preventing one or both of neural anoxia and reperfusion injury, which includes a pharmacological activator of the PKG pathway, and methods of treating or preventing medical conditions using a pharmacological activator of the PKG pathway. | 2011-12-15 |
20110306557 | NEURAL REGENERATION PEPTIDES AND METHODS FOR THEIR USE IN TREATMENT OF BRAIN DAMAGE - The invention discloses a family of neuronal migration-inducing, proliferation-promoting and neurite outgrowth promoting factors, termed NRP compounds, and provides compositions and methods for the use of NRP compounds in the treatment of brain injury and neurodegenerative disease. NRP-1 compounds induce neurons and neuroblasts to proliferate and migrate into areas of damage caused by acute brain injury or chronic neurodegenerative disease, such as stroke, trauma, nervous system infections, demyelinating diseases, dementias, and metabolic disorders. NRP compounds may be administered directly to a subject or to a subject's cells by a variety of means including orally, intraperitoneally, intravascularly, and directly into the nervous system of a patient. | 2011-12-15 |
20110306558 | PROSAPOSIN AS A NEUROTROPHIC FACTOR - Prosaposin, saposin C and various peptide fragments of saposin C stimulate neurite outgrowth in vitro. In addition, prosaposin and saposin C promote increased myelination ex vivo. Prosaposin is present in large neurons of the brain, including both upper and lower motor neurons. | 2011-12-15 |
20110306559 | METHODS AND COMPOSITIONS FOR TREATING NEUROPATHIC PAIN - Compositions and methods for the treatment of neuropathic pain are provided. Compositions of the invention may comprise proteins with a zinc-finger domain fused to a regulatory domain that is capable of either activating or repressing the expression of a target gene involved in neuropathic pain. Alternatively, compositions of the invention may comprise a nucleic acid sequence encoding a protein of the invention, which nucleic acid sequence may optionally be provided as a plasmid or within a virus or other vector for delivery to a target cell or tissue. Methods of treating neuropathic pain involving treatment of subject with the compositions of the invention are also provided. Exemplary target genes for the treatment of neuropathic pain include VR1, NaV | 2011-12-15 |
20110306560 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES - Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses. | 2011-12-15 |
20110306561 | COMPLEMENT C3a DERIVED DIMERIC PEPTIDES AND USES THEREOF - Peptide compositions comprising a dimeric peptide which combines two peptide monomers, each independently comprising the amino acid sequence: | 2011-12-15 |
20110306562 | Antisense EGFRAS Guanidinium Peptide Nucleic Acid (GPNA) Oligonucleotides as Antitumor Agents - A class of antisense agents having a distributed guanidinium peptide nucleic acids (GPNA) backbone which has excellent uptake into mammalian cells, can bind to the target DNA or RNA in a highly sequence specific manner and can resist nucleases and proteases both outside and inside the cell(s) of interest. In one embodiment, either systemic or intratumoral administration of antisense Epidermal Growth Factor Receptor (“EGFR”) GPNA oligonucleotides is believed to downmodulate EGFR levels, thus in turn to reduce head and neck squamous cell carcinoma tumor growth, which has been confirmed to date both in vitro and in vivo. | 2011-12-15 |
20110306563 | MACROLACTONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR THE TREATMENT OF CANCER - The present invention relates to the use of a compound of the formula (I), wherein X and Y independently of one another are OH, O—(C | 2011-12-15 |
20110306564 | SOLID COMPOSITION, MICROPARTICLES, MICROPARTICLE DISPERSION LIQUID, AND MANUFACTURING METHODS FOR THESE - In a dissolving step, in a container | 2011-12-15 |
20110306565 | HYALURONIC ACID CONTAINING COMPOSITIONS FOR TREATMENT OF WOUNDS, SCARS, POST-SURGICAL ADHESION FORMATION - Pharmaceutical compositions are provided for enhancing the therapeutic effect of biologically active peptides, especially peptides derived from human lactoferrin. The compositions are useful for the treatment and/or prevention of wounds, scars, and post surgical adhesions. | 2011-12-15 |
20110306566 | TOPICAL SKIN TREATMENT KITS - This invention relates to benzoyl peroxide products for skin treatment, and more particularly to a kit containing a benzoyl peroxide product and a topical moisturizing product. In one embodiment the kit contains BenzaClin® brand clindamycin-benzoyl peroxide gel and Viscontour® brand hyaluronic acid serum. | 2011-12-15 |
20110306567 | POLYSACCHARIDES WITH ANTITHROMBOTIC ACTIVITY, INCLUDING A COVALENT BOND AND AN AMINO CHAIN - The present invention relates to novel synthetic polysaccharides with antithrombotic activity, having at least one covalent bond with an amino chain, and to the preparation method thereof and to the therapeutic use thereof. | 2011-12-15 |
20110306568 | COMPOSITION CONTAINING GLUCOSYLGLYCEROL - The invention relates to a composition containing 20 to 80% w/w of glucosyl-glycerol and 0.5 to 20% w/w of one or several mono- and/or disaccharides. Surprisingly, it has been found that an especially aqueous solution containing a high concentration of glucosylglycerol offers exceptionally high long-term stability. The composition has bactericidal and fungicidal effects. | 2011-12-15 |
20110306569 | RHAMNOLIPID BIOSURFACTANT FROM PSEUDOMONAS AERUGINOSA STRAIN NY3 AND METHODS OF USE - The present disclosure relates to an isolated strain of | 2011-12-15 |
20110306570 | Na/K-Atpase Expression as an Indicator for the Treatment of Cancer - Methods for regulating the expression of Na/K-ATPase and uses thereof, including uses in the diagnosis/prognosis and treatment of cancer, are disclosed. | 2011-12-15 |
20110306571 | Methods for treating cancer - Use of a macrolide antibiotic for the manufacture of a medicament for the treatment or prevention of a cancer selected from colorectal cancer, Desmoid tumor, bladder cancer, gastric cancer, and breast cancer, the macrolide antibiotic being one or more of: tylosin, pharmaceutically acceptable salts thereof, and derivatives thereof; erythromycin, pharmaceutically acceptable salts thereof, and derivatives thereof; oleandomycin, pharmaceutically acceptable salts thereof, and derivatives thereof; and spiramycin, pharmaceutically acceptable salts thereof, and derivatives thereof. Also provided are pharmaceutical compositions and methods for the treatment or prevention of the above mentioned cancers and methods for treating or preventing, in a mammal, a cancer that expresses a mutated APC gene. | 2011-12-15 |
20110306572 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER USING COX-2 INHIBITORS AND DUAL InHIBITORS OF EGFR [ErbB1] AND HER-2 [ErbB2] - Described herein are compositions and methods for using these compositions in the treatment of cancer, tumors, and tumor-related disorders in a subject. | 2011-12-15 |
20110306573 | NUCLEOSIDE DERIVATIVES AS INHIBITORS OF VIRAL POLYMERASES - Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; wherein R | 2011-12-15 |
20110306574 | INHIBITORS OF F18+ E COLI BINDING - The present invention relates to blood group A/B/H determinant on Type 1 Core glycosphingolipids chains as recognition point for the FedF protein of F18-fimbriated Enterotoxigenic and verotoxinogenic | 2011-12-15 |
20110306575 | MEDICAL AND NUTRITIONAL APPLICATIONS OF HIGHLY REFINED CELLULOSE - The present invention provides a method for using processed-cellulose. Preferably, the processed cellulose is a highly refined cellulose (HRC). The HRC is useful in a number of medical and nutritional applications. These medical and nutritional applications can include, but are not limited to, administering effective amounts of the HRC for lowering values of risk factor measurements for such diseases as arteriosclerotic cardiovascular disease and diabetes. Treatment of other diseases and conditions with the HRC is also possible. | 2011-12-15 |
20110306576 | COMPOUNDS AND METHODS RELATING THERETO - A compound of formula (II) or a pharmaceutically acceptable derivative thereof for use in a method of combating and/or detecting a pathogen; wherein X is selected from O, S and Se; each of R | 2011-12-15 |
20110306577 | TOPICAL SKIN CREAM COMPRISING PHOSPHATIDYLCHOLINE DHA AND L-TYROSINE - The present invention relates to compositions and methods of treating skin. In particular, the present invention relates to the topical application to the skin of compositions for the prevention and/or treatment of damage to skin. | 2011-12-15 |
20110306578 | USE OF ORGANOPHOSPHORUS COMPOUNDS FOR THE THERAPEUTIC AND PROPHYLACTIC TREATMENT OF INFECTIONS - Use of organophosphorus compounds of general Formula (I) | 2011-12-15 |
20110306579 | METHODS OF NEUROPROTECTION USING NEUROPROTECTIVE STEROIDS AND A VITAMIN D - Described herein are compositions and methods for treating or preventing nervous system injury. In particular, the methods and compositions relate to the use of at least one neuroprotective steroid, such as progesterone, and vitamin D. | 2011-12-15 |
20110306580 | PROPHYLACTIC AGENT OR THERAPEUTIC AGENT FOR DISEASE RESULTING FROM ABNORMAL BONE METABOLISM - The object of the present invention is to provide a therapeutic agent or a prophylactic agent for a disease resulting from an abnormal bone metabolism, especially osteoporosis which is more effective than conventional agents. Excellent therapeutic effect or prophylactic effect on a disease resulting from an abnormal bone metabolism, especially osteoporosis, compared with the effect in administration of each compound alone can be obtained by the combination of an N-hydroxybenzamidine derivative represented by Formula (I) or a salt thereof with an activated vitamin D or a prodrug thereof. | 2011-12-15 |
20110306581 | STABLE PERFLUOROCARBON EMULSION FOR USE AS AN ARTIFICIAL OXYGEN CARRIER - Perfluorocarbon emulsions having a high stability and good oxygen release are disclosed and described. These perfluorocarbon emulsions are typically for use as artificial oxygen carriers. The perfluorocarbon emulsions include a disperse phase of a perfluorocarbon and an emulsion stabilizer, and continuous phase. The emulsion stabilizer can primarily include a poly(ethylene oxide) block copolymer. These stabilized perfluorocarbon emulsions can be used in liquid and/or hydrogel phases of perfusion bioreactors or various other culture systems to enhance cell viability in thick tissue constructs, or as blood substitutes, although other applications may also be considered. | 2011-12-15 |
20110306582 | ANDROGEN PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING DEPRESSION - The present invention relates to methods, kits, combinations, and compositions for treating, preventing or reducing the risk of developing a depressive disorder, or the symptoms associated with, or related to a depressive disorder in a subject in need thereof. The present invention also relates to a method of administering a steroid in the testosterone synthetic pathway, for example testosterone, to a subject in need thereof. In addition, the methods, kits, combinations and compositions may be used in conjunction with other pharmaceutical agents including agents effective at treating, preventing, or reducing the risk of developing a depressive disorder in a subject. | 2011-12-15 |
20110306583 | Testosterone Gel And Method Of Use - The present invention relates to an improved transdermal hydroalcoholic testosterone gen formulation that provides, among other things, a desirable pharmacokinetic hormone profile, and methods of use. | 2011-12-15 |
20110306584 | Porphyrin Catalysts and Methods of Use Thereof - This invention provides a novel class of substituted macrocyclic metallic compounds. The compounds are useful as peroxynitrite decomposition catalysts. Pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, or prodrug thereof are also described. | 2011-12-15 |
20110306585 | Metal Complexes of N-Heterocyclic Carbenes - The present invention generally relates to metal complexes of N-heterocyclic carbenes that contain one or more additional active moieties and/or groups therein. In one embodiment, the present invention relates to metal complexes of N-heterocyclic carbenes that contain an anti-fungal and/or anti-microbial moiety and/or group in combination with one or more additional active moieties and/or groups selected from fluoroquinolone compounds or derivatives thereof; steroids or derivatives thereof; anti-inflammatory compounds or derivatives thereof; anti-fungal compounds or derivatives thereof; anti-bacterial compounds or derivatives thereof; antagonist compounds or derivatives thereof; H | 2011-12-15 |
20110306586 | NMDA Receptor Modulators and Uses Thereof - Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed. | 2011-12-15 |
20110306587 | UNSATURATED NITROGEN HETEROCYCLIC COMPOUNDS USEFUL AS PDE10 INHIBITORS - Unsaturated nitrogen heterocyclic compounds of formula (I): | 2011-12-15 |
20110306588 | HETEROARYLOXYHETEROCYCLYL COMPOUNDS AS PDE10 INHIBITORS - Heteroaryloxyheterocyclyl compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive-compulsive disorder, and the like. | 2011-12-15 |