49th week of 2021 patent applcation highlights part 5 |
Patent application number | Title | Published |
20210378558 | IN VIVO RADICAL DOSIMETRY AND IN VIVO HYDROXYL RADICAL PROTEIN FOOT-PRINTING - Systems and methods of in vivo hydroxyl radical protein foot-printing are presented. These teachings may be used to, for example, study three-dimensional protein structure or bio-kinetics. Radical Dosimetry including an optional intrinsic standard is used on isolated intact cells. Real-time feedback based on an internal standard provides comparability between different experiments and in vivo analysis results in data that is representative of actual biological conditions. | 2021-12-09 |
20210378559 | SURGICAL IMPLANTS INCLUDING SENSING FIBERS - A monitoring system includes a surgical implant configured for implantation in vivo and having at least one sensing fiber configured to measure a preselected physiological parameter, and a receiving unit in wireless communication with the at least one sensing fiber and configured to receive measurements of the preselected physiological parameter. A surgical system includes an end effector having a plurality of fasteners, and a surgical implant securable to tissue via the plurality of fasteners. The surgical implant includes at least one sensing fiber configured to measure a preselected physiological parameter. | 2021-12-09 |
20210378560 | PHYSIOLOGICAL CHARACTERISTIC SENSOR SYSTEM - A physiological characteristic sensor system includes a physiological characteristic sensor. The physiological characteristic sensor includes a housing having a first housing portion coupled to a second housing portion, and an antenna coupled to the first housing portion. The physiological characteristic sensor system includes a sensor inserter configured to be coupled to the physiological characteristic sensor. The sensor inserter includes a sensor retainer, and the sensor retainer is configured to couple to the second housing portion in a second state to couple the physiological characteristic sensor to the sensor inserter. | 2021-12-09 |
20210378561 | METHODS, DEVICES, AND SYSTEMS FOR PHYSIOLOGICAL PARAMETER ANALYSIS - A method of calculating at least one physiological parameter using a reticulocyte production index (RPI) value can include: measuring a plurality of first glucose levels over a first time period; measuring a first glycated hemoglobin (HbA1c) level corresponding to an end of the first time period; measuring the RPI value; calculating a red blood cell elimination constant (k | 2021-12-09 |
20210378562 | MEDICAL MONITORING DEVICE FOR HARMONIZING PHYSIOLOGICAL MEASUREMENTS - Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer. | 2021-12-09 |
20210378563 | GLUCOSE MEASUREMENT PREDICTIONS USING STACKED MACHINE LEARNING MODELS - Glucose measurement and glucose-impacting event prediction using a stack of machine learning models is described. A CGM platform includes stacked machine learning models, such that an output generated by one of the machine learning models can be provided as input to another one of the machine learning models. The multiple machine learning models include at least one model trained to generate a glucose measurement prediction and another model trained to generate an event prediction, for an upcoming time interval. Each of the stacked machine learning models is configured to generate its respective output when provided as input at least one of glucose measurements provided by a CGM system worn by the user or additional data describing user behavior or other aspects that impact a person's glucose in the future. Predictions may then be output, such as via communication and/or display of a notification about the corresponding prediction. | 2021-12-09 |
20210378564 | METHODS AND SYSTEMS FOR EARLY SIGNAL ATTENUATION DETECTION AND PROCESSING - Provided are methods and apparatus for receiving sensor data from an analyte sensor of a sensor monitoring system, processing the received sensor data with time corresponding calibration data, outputting the processed sensor data, detecting one or more adverse conditions associated with the sensor monitoring system, disabling the output of the sensor data during the adverse condition time period, determining that the one or more detected adverse conditions is no longer present in the sensor monitoring system, retrieving the sensor data during the adverse condition time period, processing the retrieved sensor data during the adverse condition time period, and outputting the processed retrieved sensor data. | 2021-12-09 |
20210378565 | pH-Triggered Diagnostic Wound Dressing - The invention relates to a functional wound dressing being able to detect and indicate the state of the wound, in particular with regard to an infection which is reported to be frequently associated with poorly healing wounds, such as chronic wounds. The present wound dressing can be used in moist wound healing and contains a substance being able to absorb wound exudate from the wound and to provide moisture to the wound. | 2021-12-09 |
20210378566 | HYPERSATURATION INDEX - Embodiments of the present disclosure provide a hypersaturation index for measuring a patient's absorption of oxygen in the blood stream after a patient has reached 100% oxygen saturation. This hypersaturation index provides an indication of the partial pressure of oxygen of a patient. In an embodiment of the present invention, a hypersaturation index is calculated based on the absorption ratio of two different wavelengths of energy at a measuring site. In an embodiment of the invention, a maximum hypersaturation index threshold is determined such that an alarm is triggered when the hypersaturation index reaches or exceeds the threshold. In another embodiment, an alarm is triggered when the hypersaturation index reaches or falls below its starting point when it was first calculated. | 2021-12-09 |
20210378567 | BIOLOGICAL FLUID SEPARATION DEVICE - A blood separation device that allows high quality plasma to be generated using a single power source. The device includes a housing with an inlet port adapted to receive the blood sample, a first chamber having a first chamber flow channel in fluid communication with the inlet port, a second chamber having a second chamber flow channel, a separation member disposed between the first chamber and the second chamber. In some embodiments, the blood separation device detects or tests for the presence of a substance, such as an antigen or an antibody. | 2021-12-09 |
20210378568 | DEVICES AND PROCESSING SYSTEMS CONFIGURED TO ENABLE PHYSIOLOGICAL EVENT PREDICTION BASED ON BLEPHAROMETRIC DATA ANALYSIS - Devices and processing systems are configured to enable physiological event prediction based on blepharometric data analysis. For example, some embodiments provide methods and associated technology that enable retrospective analysis of blepharometric data driving subsequent hardware/software configuration, thereby to provide for personalized and/or generalized biomarker identification. | 2021-12-09 |
20210378569 | MAGNETOMETER USED FOR CARDIAC MAGNETIC FIELD MEASUREMENT AND BASED ON NITROGEN-VACANCY (NV) CENTERS IN DIAMOND, AND CARDIAC MAGNETIC FIELD MEASUREMENT SYSTEM - The present disclosure provides a cuboid magnetometer with high fluorescence collection efficiency, used for cardiac magnetic field measurement, and based on nitrogen-vacancy (NV) centers in diamond, and a cardiac magnetic field measurement system. The cardiac magnetic field measurement system includes a magnetic shielding chamber, a non-magnetic bed, an array probe for cardiac magnetic field measurement, a three-axis displacement platform, a high-speed data collection card, a fiber laser source, a microwave source, and a computer. The array probe for cardiac magnetic field measurement includes a non-magnetic shell, a stepping motor, a porous rotary fiber coupling apparatus, a fiber bundle set, a special photodetector (PD) set, a filter set, a ring-shaped antenna, and special diamond. | 2021-12-09 |
20210378570 | HEAD-MOUNTABLE APPARATUS - Head-mountable apparatus for measuring magnetic brain response to auditory stimuli is disclosed. The apparatus comprises a first case adapted to be mounted on the head on the right auditory cortex, wherein the first case houses a first set of optically pumped magnetometers for measuring magnetic brain response to auditory stimuli. The apparatus also comprises a second case adapted to be mounted on the head on the left auditory cortex, wherein the second case houses a second set of optically pumped magnetometers for measuring magnetic brain response to auditory stimuli. Finally, the apparatus comprises at least one output interface for transmitting measurement data from the apparatus. | 2021-12-09 |
20210378571 | COMPOSITE BIOELECTRODES - A computing device may include (1) biosignal-acquiring circuitry that captures a biosignal from a user's body and (2) one or more composite bioelectrodes electrically coupled to the biosignal-acquiring circuitry. The one or more composite bioelectrodes may include (1) a circuitry-interfacing side with a mechanical or electrical property having a first predetermined configuration and (2) a user-interfacing side with the mechanical or electrical property having a second predetermined configuration. Various other composite bioelectrodes, systems, and methods are also disclosed. | 2021-12-09 |
20210378572 | INDUCTOR-CAPACITOR BASED SENSOR APPARATUSES - An example sensor apparatus includes two inductors with a first elastomer material between and at least one capacitor coupled to the two inductors. The at least one capacitor is configured, while in use, to at least partially wrap a circumference of an object and to exhibit a change in impedance in response to a pressure-manifestation change associated with the object, the change in impedance is to cause a change in the resonant frequency of the two inductors. | 2021-12-09 |
20210378573 | CATHETER - A catheter has excellent in torque transmission properties to easily process a distal end portion of a catheter shaft to form a side hole, thereby protecting a lead wire that is inserted in a side hole. The catheter includes a shaft, ring-shaped electrodes that are mounted at an outer peripheral surface of a distal end portion of the shaft, and electrode lead wires. The shaft is made up of a braid that is embedded in a tube wall over an entire length of the shaft, side holes are formed in a tube wall of the distal end portion of the shaft, a distal end portion of each lead wire is joined to an inner peripheral surface of each electrode, the lead wires are inserted into the side holes and thus pass through meshes of the braid and enter a lumen of the shaft, and the side holes in which the lead wires are inserted are filled with a resin material. | 2021-12-09 |
20210378574 | THIN-FILM HIGH-DENSITY SENSING ARRAY, SUB-SCALP IMPLANTATION TOOL AND IMPLANT METHOD - Devices, systems and techniques are provided to facilitate chronic monitoring of biological signals. An implant device can include a set of branch portions. Each branch portion can include multiple electrodes disposed on a bottom surface and can have vias that connect the electrode to a trace on the top of the branch portion. Each branch portion can include a hole through which a connector (e.g., suture) can be pulled. The connector can also be threaded through a hole in a curved arm of an implantation tool, To implant the implant device, the implantation tool can be inserted through an incision, moved to a target location and stabilized. An end of the connector can then be pulled, which can cause the implant device to move to the target location. The implant device can then be stabilized and the implantation tool explanted. | 2021-12-09 |
20210378575 | Coated Electroencephalogram Electrodes - Subdermal electroencephalogram (EEG) electrodes are coated to minimize pain and bleeding, and to improve electrical signal transmission. | 2021-12-09 |
20210378576 | NON-INVASIVE PREDICTION OF RISK FOR SUDDEN CARDIAC DEATH - A method and apparatus for the quantitative determination of an individual's risk for sudden cardiac death (SCD) is described. Risk stratification is accomplished (and may have a sensitivity and specificity of greater than about 90%) by determining the presence in any individual being tested for SCD risk of sequences identified herein to correlate quantitatively with SCD risk. Both the number of such sequences present and their alignment scores (similarity) with the SCD risk sequence ensemble are used to calculate quantitative SCD risk. | 2021-12-09 |
20210378577 | METHOD AND APPARATUS FOR ANALYZING ELECTROCARDIO SIGNAL, AND SIGNAL RECORDER AND THREE-DIMENSIONAL MAPPING SYSTEM - Disclosed relates to a method and an apparatus for analyzing an ECG signal, an electrophysiological signal recorder, a three-dimensional mapping system, and a computer device. The method includes: acquiring (S | 2021-12-09 |
20210378578 | Heart Rate Detection Method, Heart Rate Detection Device and Program - A heartbeat detection device includes a heartbeat time calculation unit configured to calculate a heartbeat time from a sampling data string of an electrocardiographic waveform, a heart rate calculation unit configured to calculate, for each heartbeat time, a heart rate from the heartbeat time calculated by the heartbeat time calculation unit, and a skip period calculation unit configured to calculate, based on the heart rate calculated by the heart rate calculation unit, a length of a skip period every time the heartbeat time is calculated. If a time difference between a latest time calculated from the sampling data string and an immediately preceding heartbeat time is not longer than the length of the skip period calculated from the immediately preceding heartbeat time, the heartbeat time calculation unit does not adopt, as a heartbeat time, the latest time calculated from the sampling data string. | 2021-12-09 |
20210378579 | LOCAL NOISE IDENTIFICATION USING COHERENT ALGORITHM - Systems, devices, and techniques are disclosed for automatically detecting arrhythmia locations. The systems, devices, and techniques include a plurality of body surface electrodes configured to sense electrocardiogram (ECG) data. The systems, devices, and techniques include a processor including a neural network configured to receive a plurality of historical ECG data and corresponding arrhythmia locations determined based on each of the plurality of historical ECG data, train a learning system based on the plurality of historical ECG data and corresponding arrhythmia locations, generate a model based on the learning system. New ECG data may be received from the plurality of body surface electrodes and the processor may provide a new arrhythmia location based on the new ECG data. Additionally, a new coherent mapping adjustment may be provided based on a model that is trained using historical coherent mapping adjustments. | 2021-12-09 |
20210378580 | BRAIN WAVE MONITORING SYSTEM AND METHOD THEREOF - A brain wave monitoring system includes an electronic device and at least one electroencephalograph connected to the electronic device, each electroencephalograph includes 8 channels respectively connected to a corresponding electrode for receiving a brain wave signal. The electronic device scans a number of the at least one electroencephalograph and sequentially displays multiple channels of the at least one electroencephalograph according to an identifier of each of the at least one electroencephalograph. The brain wave monitoring system can automatically detect the number of electroencephalographs connected to the electronic device, and display the brain wave signals of all channels of all electroencephalographs according to the number of electroencephalographs and 8 channels of each electroencephalograph. The brain wave monitoring system can also prompt a guide message according to a channel impedance value and a signal quality index to assist a user improving a quality of the brain wave. | 2021-12-09 |
20210378581 | NEURAL ANALYSIS AND TREATMENT SYSTEM - A neural analysis and treatment system includes a computing device with a memory for storing an application that is executable on a processor to receive amplitude-integrated electroencephalography (aEEG) and range-EEG (rEEG) measurements associated with a patient. The systems determine a spectral edge frequency (SEF) measurement from the received EEG measurements, and determine one or more neural characteristics of the patient according to the determined SEF, aEEG, and rEEG measurements. These neural characteristics may then be used to identify and implement an appropriate therapeutic treatment. | 2021-12-09 |
20210378582 | SYSTEMS AND METHODS FOR ASSESSING STROKE RISK - A system for assessing stroke conditions includes a wearable stimulator and a sensor device configured to obtain physiological data from a patient. The sensor device can include electrodes configured to detect electrical signals corresponding to brain activity. A computing device communicatively coupled to the wearable stimulator and the sensor device is configured to receive the physiological data and analyze the physiological data to provide a patient stroke assessment. | 2021-12-09 |
20210378583 | METHOD AND SYSTEM FOR MONITORING A SUBJECT - A method for monitoring a subject, includes: capturing high-bandwidth data pertaining to the subject; cyclically storing a recent portion of the high-bandwidth data in a first memory; monitoring one or more physiological signals of the subject; analyzing the monitored physiological signals to allow detection of one or more target events; upon detection of a target event: copying a then recent portion of the high-bandwidth data from the first memory to a second memory; and storing high-bandwidth captured in a predetermined period subsequent to the detection in the second memory. The one or more physiological signals include EEG. The one or more target events include epileptic seizures. A computer program product and a system may use the method. | 2021-12-09 |
20210378584 | ORAL TOOL - An oral tool is provided that includes a body and a measurement unit. The measurement unit is disposed in a movable configuration with respect to the body, and includes a sensor unit at an end opposite to an end where the body is disposed. The sensor unit is constructed to be inserted into a mouth. The end of the measurement unit opposite to the end where the sensor unit is disposed is disposed inside the body. The oral tool includes a stress reliever disposed between the measurement unit and the body at a portion where the measurement unit changes a distance from the body while moving. | 2021-12-09 |
20210378585 | FETAL HEALTH MONITORING SYSTEM AND METHOD FOR USING THE SAME - Wearable fetal health monitoring device for determining a heath condition of a fetus based on biosignals of an expecting mother and the fetus is provided. The device includes a MEMS accelerometer that converts an acoustic wave sensed in an abdominal region into an abdominal acoustic signal. The device also includes a pulse oximeter generates a maternal photoplethysmogram (mPPG) value from a pulse sensed in the abdominal region. The device further includes a microcontroller configured to: generate a maternal phonocardiogram (mPCG) value from the abdominal acoustic signal; calculate a first maternal heart rate (mHR) value from the mPCG value; calculate a second mHR value from the mPPG value; compare the first mHR value with the second mHR value to identify a noise correction value; and apply the identified noise correction value to the mPCG value to extract a fetal phonocardiogram (fPCG) value. | 2021-12-09 |
20210378586 | SKIN TANNING MEASURING DEVICE - A Skin Tanning Measuring Device is provided to determine tanning level and skin penetration to various wavelengths, comprising of a device capable to inject light into the skin and monitor the light level emerging out from the skin tissue at a different location. By measuring the amount of emerging light, an individual tanning level could be deducted based on at least one additional measurement performed at an untanned location. The measurements will be used to compare between those levels and the saturated tanning levels, and will issue out a warning when the tanning is too high and additional exposure may be hazardous. Moreover, the offered system will measure skin penetration to UV hazardous radiation with and without sunscreen protection. The device will also provide information regarding melanin absorption as a function of UV exposure, and monitor those values over time and issue out a warning to users. | 2021-12-09 |
20210378587 | System and Method for Determining a Subject's Muscle Fuel Level, Muscle Fuel Rating, and Muscle Energy Status - Provided is a non-invasive system and method for determining a fuel value for a target muscle and potentially at least one indicator muscle. The method includes receiving an ultrasound scan of a target muscle; evaluating at least a portion of the ultrasound scan to determine fuel value within the target muscle; recording the determined fuel value for the muscle as an element of a data set for the muscle; evaluating the fuel data set to determine a value range; and in response to the range being at least above a pre-determined threshold, establishing a target score for the muscle as based on an upper portion of the value range. The method may be repeated to identify ranges for a plurality of muscles, the muscle with the greatest range being identified as an indicator muscle. Based on these findings the muscles estimated fuel level, fuel rating and energy status may be determined. An associated system is also disclosed. | 2021-12-09 |
20210378588 | KNEE LIGAMENT EVALUATION SYSTEM AND METHOD - Disclosed herein is a joint evaluation device and corresponding systems and methods for evaluating ligaments and other soft tissue connections between, for example, a tibia and a femur at a knee joint. The joint evaluation device being arranged and configured to induce and measure forces while positions of the tibia and femur are monitored. Some embodiments use a computer assisted surgery device to track positions of the tibia and the femur, and may include a computing device configured to evaluate the forces measured between a first engagement portion and a second engagement portion of the joint evaluation device to output information related to the status of the ligament and other soft tissue connections prior to any bone resections being made to the tibia or the femur. | 2021-12-09 |
20210378589 | FLUID REPLACEMENT DEVICE - A fluid replacement method including: determining the amount of urine expelled by a patient; infusing via a pump fluid from a first fluid source into a patient; determining an amount of fluid infused into the patient from the first fluid source; adjusting the operating of the pump based on the determined amount of urine expelled and the amount of fluid infused into the patient; setting a desired fluid balance for the patient; setting an amount of at least one additional fluid delivered to the patient, wherein the at least one additional fluid is not pumped into the patient; calculating an actual fluid balance based on the determined urine output, the determined amount of fluid infused into the patient from the first fluid source, and the set amount of said at least one additional fluid delivered to the patient; and automatically controlling the pump based on the actual fluid balance and the set desired fluid balance so the actual fluid balance conforms to the desired fluid balance. | 2021-12-09 |
20210378590 | SYSTEM AND METHOD FOR DETECTING CYANIDE EXPOSURE - In an example, a method of detecting cyanide exposure of an individual comprises measuring a thiocyanate level of the individual, and comparing the measured thiocyanate level to a preset thiocyanate threshold to determine whether the measured thiocyanate level is above the preset thiocyanate threshold indicating a level of acute cyanide poisoning for which medical treatment is recommended to treat health effects of the exposure. | 2021-12-09 |
20210378591 | PROCESS FOR VISUAL DETERMINATION OF TISSUE BIOLOGY - A method of analysing a target bodily tissue of a subject. The method involves manipulating image data from the target bodily tissue and a background bodily tissue after dosing the subject with a contrast agent. The relative intensities of the light emitted from selected areas of the target bodily tissue and background bodily tissue at different time points after dosing are compared to determine whether 1) the intensity of light emitted from the target bodily tissue is lower than the intensity of light emitted from the background bodily tissue during the first part of the time period; and/or 2) the intensity of light emitted from the target bodily tissue is higher than the intensity of light emitted from the background bodily tissue during the second part of the time period; to assist in the determination of whether the target bodily tissue is benign or malignant. | 2021-12-09 |
20210378592 | LINER FOR ADHESIVE SKIN PATCH - A liner associated with an adhesive skin patch of a physiological characteristic sensor deployed with a sensor inserter having a housing with a removable cover includes a surface to couple to the adhesive skin patch. The liner includes a removal portion to couple the liner to the removable cover of the sensor inserter such that a separation of the removable cover from the housing removes the liner from the adhesive skin patch. | 2021-12-09 |
20210378593 | Catheter Assembly Including Transitioning Lumens - A venous catheter assembly includes a hub with opposing suture wings, an extension leg coupled to the hub, and an elongate catheter tube designed for insertion into a blood vessel of a patient. The elongate catheter tube is coupled to the hub and includes at least one fluid-carrying lumen within the outer wall extending between a proximal end and a distal end of the elongate catheter tube. The fluid-carrying lumen is in fluid communication with the extension leg and an opening in the outer wall at the distal end of the elongate catheter tube. The elongate catheter tube also includes at least one terminating lumen within the outer wall extending to a closed termination point. | 2021-12-09 |
20210378594 | FEATURES TO ASSIST IN ASSEMBLY AND TESTING OF DEVICES - In one embodiment, a catheter manufacturing method includes forming flexible circuit strips with respective different symbols marked thereon, each strip including at least one respective electrode, attaching one end of each of the flexible circuit strips to a catheter coupler with the flexible circuit strips being ordered around a circumference of the catheter coupler responsively to the respective symbols of respective ones of the flexible circuit strips, and forming a distal end assembly of a catheter, the distal end assembly comprising the flexible circuit strips attached to the catheter coupler. | 2021-12-09 |
20210378595 | METHODS FOR SENSING OR STIMULATING ACTIVITY OF TISSUE - An intravascular device for placement within an animal vessel, the intravascular device being adapted to at least one of sense and stimulate activity of neural tissue located outside the vessel proximate the intravascular device. | 2021-12-09 |
20210378596 | LINER FOR ADHESIVE SKIN PATCH - A liner associated with an adhesive skin patch of a physiological characteristic sensor includes a first end opposite a second end. The liner includes a first side opposite a second side. The liner includes a surface to couple to the adhesive skin patch, at least a portion of which extends from the first end to the second end. The liner includes at least one graspable member defined between the first side and the second side that extends beyond the first end or the second end to initiate a peel of the liner from the adhesive patch at a center of the liner. | 2021-12-09 |
20210378597 | REDUCING NOISE OF INTRACARDIAC ELECTROCARDIOGRAMS USING AN AUTOENCODER AND UTILIZING AND REFINING INTRACARDIAC AND BODY SURFACE ELECTROCARDIOGRAMS USING DEEP LEARNING TRAINING LOSS FUNCTIONS - A system and method include a memory storing processor executable code for a denoised autoencoder, and one or more processors coupled to the memory to execute the processor executable code to receive raw signal data comprising signal noise, encode, by the denoised autoencoder, the raw signal data by performing a denoising autoencoder operation to produce a latent representation, and decode, by the denoised autoencoder, the latent representation to produce clean signal data reconstructed without the signal noise. A first filter is applied to a signal to emphasize activity within the signal and to produce a first modified signal, a rectifier and a second filter are applied to the first modified signal to smooth areas of the first modified signal with clinical importance and to produce a second modified signal, and high frequency energy zones of the second modified signal are automatically detected using an energy threshold to produce a weights vector. | 2021-12-09 |
20210378598 | METHODS AND APPARATUS FOR TIME-VARYING FILTERING OF SIGNALS OF CONTINUOUS ANALYTE MONITORING SYSTEMS - A method of filtering a signal in a continuous analyte monitoring (CAM) system includes applying time-varying filtering to the signal using a time-varying filter to generate a filtered continuous analyte monitoring signal during an analyte monitoring period. Other methods, apparatus, continuous analyte monitoring devices, and continuous glucose monitoring devices are also disclosed. | 2021-12-09 |
20210378599 | METHODS AND APPARATUS FOR ADAPTIVE FILTERING OF SIGNALS OF CONTINUOUS ANALYTE MONITORING SYSTEMS - A method of filtering a signal in a continuous analyte monitoring system (CAM) includes applying adaptive filtering to the signal using an adaptive filter to generate a filtered continuous analyte monitoring signal during an analyte monitoring period, and increasing the adaptive filtering applied to the signal as a function of increasing noise on the signal. Other methods, apparatus, continuous analyte monitoring devices, and continuous glucose monitoring devices are also disclosed. | 2021-12-09 |
20210378600 | SYSTEMS AND METHODS TO DETERMINE A RISK FACTOR RELATED TO DEHYDRATION AND THERMAL STRESS OF A SUBJECT - Systems and methods to determine a risk factor related to dehydration and thermal stress of a subject are disclosed. Exemplary implementations may: generate output signals, by one or more sensors worn on a body of a subject, conveying information related to one or more of location of the subject, motion of the subject, temperature of the subject, cardiovascular parameters of the subject; store information related to the subject; obtain the output signals; determine in an ongoing manner, from the output signals, values of a water loss metric that correlates with estimated percentage of bodyweight of the subject lost in water; obtain heat index information for a contextual environment surrounding the subject; determine in an ongoing manner, from the output signals, values of an exertion metric that correlates with exertion of the subject due to work; and determine in an ongoing manner values for an aggregated risk factor of the subject. | 2021-12-09 |
20210378601 | ANALYTE MONITORING SYSTEMS AND METHODS - Improved graphical user and digital interfaces for analyte monitoring systems are provided. For example, disclosed herein are various embodiments of GUIs including Time-in-Ranges, Analyte Level/Trend Alert, and sensor usage interfaces. In addition, various embodiments of digital interfaces are described, including methods for data backfilling, expired or failed sensor transmissions, merging data from multiple devices in an analyte monitoring system, transitioning a previously activated analyte sensor to a new reader device, and autonomous sensor system alarms, among other embodiments. | 2021-12-09 |
20210378602 | BLOOD PRESSURE ESTIMATING APPARATUS AND BLOOD PRESSURE ESTIMATING METHOD - A blood pressure estimating apparatus includes a sensor configured to obtain a bio-signal of an object; and a processor configured to extract a first cardiovascular feature and a second cardiovascular feature based on the bio-signal, and estimate blood pressure based on a first changing tendency of the first cardiovascular feature from a first reference level and a second changing tendency of the second cardiovascular feature from a second reference level, the first changing tendency and the second changing tendency being independent from each other. | 2021-12-09 |
20210378603 | RESPIRATORY MODELING USING DEEP LEARNING FOR MR IMAGING WITH PILOT TONE NAVIGATION - The disclosure relates to techniques for triggering magnetic resonance data acquisition. The techniques include detecting a respiration direction of a respiration signal of an acquisition subject, predicting in real time an amplitude peak value of an expiration signal in the current respiration period according to the real-time respiration signal of the acquisition subject, multiplying the amplitude peak value by a preset coefficient, and using the product as a trigger point threshold of the current respiration period. When it is determined that an expiration stage of the current respiration period is starting, the techniques also include calculating in real time or periodically the absolute value of the difference between the amplitude of the current expiration signal and the trigger point threshold currently calculated, and if the absolute value of the difference is less than a preset difference threshold, then triggering MR data acquisition. | 2021-12-09 |
20210378604 | ALARM CHARACTERIZATION FOR ANALYTE MONITORING DEVICES AND SYSTEMS - Methods and apparatus including determining a rate of occurrence of a glycemic excursion event, determining a frequency of an alarm activation associated with the glycemic excursion event, determining an analyte level associated with the alarm activation, and setting an alarm parameter based on one or more of the determined rate of occurrence of the glycemic excursion event, the frequency of the alarm activation associated with the glycemic excursion event or the determined analyte level are provided. | 2021-12-09 |
20210378605 | WEIGHTBEARING SIMULATION ASSEMBLY AND METHODS OF USING THE SAME TO IMAGE A SUBJECT - A weightbearing simulation assembly includes a substrate comprising a mounting surface extending in a first direction a subject support disposed on a first region of the mounting surface and a pedal assembly disposed on a second region of the mounting surface. The pedal assembly includes a spring assembly including a contact plate facing the subject support, a compression plate, and a first spring disposed between the contact plate and the compression plate. A subject applies a compressive force to the contact plate in a compression direction to simulate a load-bearing condition by compressing the first spring. An orientation of the pedal assembly may be adjusted to change a relative angle between the compression direction and the first direction to alter an imaging angle. | 2021-12-09 |
20210378606 | SYSTEMS AND METHODS TO CONTROL RADIATION SCANNER POSITIONING - An example scanner positioning control system includes: a display; a processor; and a computer readable storage medium comprising computer readable instructions which, when executed, cause the processor to: output, via the display, a first visual representation of an arrangement of a radiation source, a radiation detector, and a workpiece positioner; identify a change to be made to the arrangement of at least one of the radiation source, the radiation detector, or the workpiece positioner; output, via the display, a second visual representation of the arrangement of the radiation source, the radiation detector, and the workpiece positioner based on the change to be made to the arrangement; and control a scanner positioning system to physically move the at least one of the radiation source, the radiation detector, and the workpiece positioner based on the change. | 2021-12-09 |
20210378607 | Adjustable Couch and Medical Couch System Comprising Same - An embodiment of the present disclosure provides an adjustable couch that can be mounted on a medical couch, the adjustable couch comprising: a first couch provided with a fixing means to be fixed to the medical couch; and a second couch disposed on the first couch and provided with a rotating-coupling means to be coupled rotatably about a first axis perpendicular to an upper surface of the first couch. | 2021-12-09 |
20210378608 | SYSTEMS AND METHODS FOR A STATIONARY CT IMAGING SYSTEM - Various methods and systems are provided for stationary CT imaging. In one embodiment, a modular imaging system comprises a plurality of distributed x-ray units releasably coupled to a plurality of detector arrays, with the plurality of distributed x-ray units and the plurality of detector arrays forming a self-supporting structure including a central opening shaped to receive a subject to be imaged. The modular imaging system may image the subject without rotation of the distributed x-ray units or detector arrays around the subject. | 2021-12-09 |
20210378609 | SYSTEMS AND METHODS FOR A STATIONARY CT IMAGING SYSTEM - Various methods and systems are provided for stationary computed tomography (CT) imaging. In one embodiment, a stationary CT system includes one or more detector arrays extending around at least a portion of an imaging volume, a stationary distributed x-ray source unit comprising a plurality of emitters including a first set of emitters configured to operate at a first voltage and a second set of emitters configured to operate at a second voltage, different than the first voltage, and a source controller for triggering the first set of emitters for acquiring first projection data by the one or more detector arrays and triggering the second set of emitters for acquiring second projection data by the one or more detector arrays, the first projection data and the second projection data usable to reconstruct one or more basis material composition images or monochromatic images of an object within the imaging volume. | 2021-12-09 |
20210378610 | CIRCULAR-ARC-SHAPED HYBRID C-PROFILE FOR A C-ARM X-RAY APPARATUS - The present technology relates to a circular-arc-shaped hybrid C-profile for a C-arm X-ray apparatus, said profile having a lightweight profile as the main body and a steel profile as a support profile for a bearing unit, the lightweight profile and the steel profile being connected to one another by connecting means. | 2021-12-09 |
20210378611 | SYSTEMS AND METHODS FOR A STATIONARY CT IMAGING SYSTEM - Various methods and systems are provided for stationary CT imaging. In one embodiment, an imaging system comprises a chamber shaped to enclose a subject to be imaged, a support surface disposed within the chamber and shaped to maintain the subject in an upright position, and an annular imaging unit encircling the chamber and having a fixed angular orientation to the chamber, the annular imaging unit including a distributed x-ray unit and a detector array arranged opposite to each other across the chamber. The imaging system may image the subject without rotation of the annular imaging unit. | 2021-12-09 |
20210378612 | X-RAY IMAGING SYSTEM - Provided is an X-ray imaging system capable of performing X-ray imaging quickly. The X-ray imaging system is provided with: an X-ray tube device including a cathode and an anode, the X-ray tube device being capable of performing X-ray imaging by irradiating an imaging target with X-rays in a state of rotating the anode; a light irradiation device including a collimator defining an X-ray irradiation range of the X-rays with respect to the imaging target, a visible light irradiation unit for emitting visible light to the imaging target and a light irradiation operation unit for performing an operation for making the visible light irradiation unit in the light irradiation state; and a controller for controlling operations of the X-ray tube device and the light irradiation device. The controller rotates the anode at an imaging possible rotation speed capable of performing X-ray imaging when the light irradiation operation unit is operated. | 2021-12-09 |
20210378613 | X-RAY IMAGING DEVICE - When a first-stage push-button switch of an operation unit ( | 2021-12-09 |
20210378614 | RADIOGRAPHIC IMAGING DEVICE - After an operator presses a practice mode execution start switch displayed on a touch panel liquid crystal display unit in an operation unit ( | 2021-12-09 |
20210378615 | CONTROL APPARATUS, RADIOGRAPHY SYSTEM, CONTROL PROCESSING METHOD, AND CONTROL PROCESSING PROGRAM - A CPU specifies whether or not a structure of a specific shape having transmittance of radiation lower than a patient is present in an imaging region of a radioscopy apparatus that captures a radiographic image with the radiation emitted from a radiation source, based on the specific shape. The CPU performs control for setting an imaging region excluding the structure as the imaging region before irradiation of the radiation is performed from the radiation source in a case where the structure is present. | 2021-12-09 |
20210378616 | METHOD AND SYSTEM OF VERTEBRAL COMPRESSION FRACTURE DETECTION - The present invention discloses a method and a system of vertebral compression fracture detection. The method of vertebral compression fracture detection includes: recombining a plurality of anatomical images captured in at least a spine segment of a target individual into a 3D image; using a multi-planar reconstruction method to reformat the 3D image to obtain at least one sagittal reformatted image; using a classification model to determine whether the sagittal reformatted image covers the middle section of the vertebral column or not; using a vertebral detection method to detect each vertebral body in the sagittal reformatted image covering the middle section of the vertebral column; using a keypoint localization method to localize a plurality of keypoints of each vertebral body which was detected in the sagittal reformatted image; evaluating the compression fracture grade of each vertebral body in the sagittal reformatted image. | 2021-12-09 |
20210378617 | PROCESSING APPARATUS, METHOD OF OPERATING PROCESSING APPARATUS, AND OPERATION PROGRAM FOR PROCESSING APPARATUS - A body thickness conversion unit converts a body thickness from a distance image imaged by a distance measurement camera to acquire the body thickness. A strength setting unit sets strength of noise reduction processing to a radiographic image to be stronger as the body thickness is thicker. A radiographic image acquisition unit acquires the radiographic image output from a radiation detector in radioscopy. A noise reduction processing unit executes the noise reduction processing on the radiographic image with the strength set by the strength setting unit. | 2021-12-09 |
20210378618 | SYSTEMS AND METHODS FOR A STATIONARY CT IMAGING SYSTEM - Various methods and systems are provided for stationary CT imaging. In one embodiment, an imaging system comprises a stationary distributed x-ray source unit comprising a plurality of emitters positioned to emit x-ray beams through the imaging volume, one or more detector arrays extending around at least a portion of an imaging volume, each detector array comprising a plurality of detector elements, each detector element configured to receive x-ray beams from more than one emitter, and an anti-scatter device configured to be positioned between one or more emitters of the plurality of emitters and an object in the imaging volume. | 2021-12-09 |
20210378619 | SYSTEMS AND METHODS FOR A STATIONARY CT IMAGING SYSTEM - Various methods and systems are provided for stationary CT imaging. In one embodiment, a method for an imaging system includes activating an emitter of a plurality of emitters of a stationary distributed x-ray source unit to emit an x-ray beam toward an object within an imaging volume, where the x-ray source unit does not rotate around the imaging volume, receiving the x-ray beam at a subset of detector elements of a plurality of detector elements of one or more detector arrays, sampling the plurality of detector elements to generate a total transmission profile, an attenuation profile, and a scatter measurement, generating a scatter-corrected attenuation profile by entering the total transmission profile, the attenuation profile, and the scatter measurement as inputs to a model, and reconstructing one or more images from the scatter-corrected attenuation profile. | 2021-12-09 |
20210378620 | SYSTEMS AND METHODS FOR DIGITAL RADIOGRAPHY - Systems and methods for digital radiography are provided. The method may be implemented on the implemented on a DR system including an imaging device and a computing device. The computing device may include at least one processor and at least one storage device. The method may include directing multiple dose sensors to detect a dose of radiation rays emitted from a radiation source of the imaging device. The multiple dose sensors may correspond to multiple imaging detectors, respectively. The method may also include determining the dose of the radiation rays. The method may further include directing, based on the dose of the radiation rays, at least one imaging detector of the multiple imaging detectors to proceed to detect the radiation rays for generating an image of a target object to be examined. | 2021-12-09 |
20210378621 | RADIATION IMAGING SYSTEM AND RADIATION IMAGING APPARATUS - A radiation imaging system is provided. The system comprises a radiation imaging apparatus including a plurality of pixels for acquiring radiation image data and a detection unit for performing exposure control during radiation irradiation, and a radiation control apparatus configured to control a radiation source that irradiates radiation to the radiation imaging apparatus. The radiation imaging apparatus and the radiation control apparatus transmit signals that relate to exposure control by wireless communication. The radiation imaging apparatus, in a case where an irradiation stop signal indicating that radiation irradiation has been stopped is not received from the radiation control apparatus after a signal instructing to stop radiation irradiation has been transmitted to the radiation control apparatus and until a first time interval has elapsed, transmits a signal instructing to stop radiation irradiation to the radiation control apparatus again. | 2021-12-09 |
20210378622 | PROCESSING APPARATUS, METHOD OF OPERATING PROCESSING APPARATUS, AND OPERATION PROGRAM FOR PROCESSING APPARATUS - A body thickness conversion unit converts a body thickness from a distance image imaged by a distance measurement camera to acquire the body thickness. A setting unit sets a gradation transformation function for use in gradation transformation processing to a radiographic image corresponding to the body thickness. A radiographic image acquisition unit acquires the radiographic image output from a radiation detector in radioscopy. A gradation transformation processing unit starts the gradation transformation processing with the gradation transformation function set by the setting unit. | 2021-12-09 |
20210378623 | Control System For X-Ray Imaging System - An x-ray system comprising: at least two system statuses; at least one system status value associated with at least one of the at least two system statuses; at least one trigger; at least one activation parameter associated with the at least one trigger; the at least one activation parameter is selected from the group consisting of: (a) at least one system status value; (b) at least one system status value with a tolerance; and (c) at least one range of system status values; at least one set associated with the at least one trigger, the at least one set comprises at least one system status parameter, the at least one system status parameter comprises at least one of: (1) a system status value; (2) a system status value with a tolerance; and (3) a range of system status values; and wherein the system status is changed according to the set upon activation of the at least one trigger. | 2021-12-09 |
20210378624 | APPARATUS AND METHODS FOR PREDICTING IN VIVO FUNCTIONAL IMPAIRMENTS AND EVENTS - Methods, devices and systems for predicting non-clinical, undiagnosed conditions through audio data related to intestinal sounds of a patient or subject, wherein the methods, devices and systems utilize machine learning algorithms, and predicting the likelihood of in vivo impairment relative to the identified spectral events. | 2021-12-09 |
20210378625 | STETHOSCOPE HEAD AND STETHOSCOPE ASSEMBLY HAVING THE SAME - The present invention provides a stethoscope head switchable between a digital mode and a conventional mode. The stethoscope head comprises a housing, a chestpiece, a switching mechanism, a microphone, a speaker, and a first power switch. The microphone is configured for receiving acoustic signals from the chestpiece. The speaker is configured for playing the acoustic signals received by the microphone. The first power switch is configured to be engaged by the switching mechanism. The switching mechanism is configured for switching the stethoscope head between the digital mode and the conventional mode when engaged by the first power switch. | 2021-12-09 |
20210378626 | ULTRASONIC IMAGING SYSTEM AND BLOOD FLOW IMAGING METHOD - An ultrasonic imaging system and an imaging method. The imaging method comprises: transmitting a divergent ultrasonic beam to a scanning object, and scanning the scanning object with the divergent ultrasonic beam (S | 2021-12-09 |
20210378627 | Ultrasound-Guided Alignment And Insertion Of Percutaneous Cannulating Instruments - A device and method for directing a cannula toward a target location under a patient's skin. The device is handheld and the device operations may be automated. The device includes an imaging probe for imaging the target location, a positioning unit for manipulating a cannula towards the target location, and a processor. The processor receives imaging data from the imaging probe, cannula pose data from at least one cannula position sensor, and device pose data from at least one device position sensor. The target location is identified from the imaging data, and a trajectory for manipulating the cannula towards the target location is determined based on the imaging data, the cannula pose data, and the device pose data. The processor may determine that the trajectory becomes misaligned with the target position, and may update to a corrected trajectory based on the imaging data, cannula pose data, and the device pose data. | 2021-12-09 |
20210378628 | ULTRASOUND PROBE WITH AN INTEGRATED NEEDLE ASSEMBLY AND A COMPUTER PROGRAM PRODUCT, A METHOD AND A SYSTEM FOR PROVIDING A PATH FOR INSERTING A NEEDLE OF THE ULTRASOUND PROBE - A device and system for and methods of using an ultrasound probe housing containing ultrasound probes configured to produce images inside the body of a patient for procedures requiring needle or probe insertion. The ultrasound probe housing can be configured with a guide channel cut-out or aperture between the ambient side and body side of a patient. A needle guide assembly may be pivotally connect internal to the guide channel cut-out or aperture of the ultrasound probe housing at a pivot point such that during use the needle enters the patient through the needle guide assembly within the ultrasonic probe housing so that the needle can be visualized by the ultrasonic probes in real time. The ultrasound probe housing may also provide an adhesion or suction quality to the body side of the device to facilitate aspects of the invention. | 2021-12-09 |
20210378629 | MONITORING APPARATUS FOR MONITORING AN ABLATION PROCEDURE - The present invention relates to a monitoring apparatus for monitoring an ablation procedure. The monitoring apparatus comprises an ultrasound signal providing unit for providing an ultrasound signal that depends on received echo series of an object that is ablated. The monitoring apparatus further comprises an ablation depth determination unit for determining an ablation depth from the provided ultrasound signal. The ablation depth can be determined directly from the ultrasound signal and is an important parameter while performing an ablation procedure. For example, it can be used for determining the progress of ablation within the object and for determining when the ablation has reached a desired progression. | 2021-12-09 |
20210378630 | SYSTEMS FOR ULTRASOUND TREATMENT - Embodiments provide an ultrasound treatment system. In some embodiments, the system includes a removable transducer module having an ultrasound transducer. In some embodiments, the system can include a hand wand and a control module that is coupled to the hand wand and has a graphical user interface for controlling the removable transducer module, and an interface coupling the hand wand to the control module. The interface may provide power to the hand wand or may transfer a signal from the hand wand to the control module. In some embodiments, the treatment system may be used in cosmetic procedures on at least a portion of a face, head, neck, and/or other part of a patient. | 2021-12-09 |
20210378631 | Real-Time 3-D Ultrasound Reconstruction of Knee and Its Implications For Patient Specific Implants and 3-D Joint Injections - Methods and apparatus for treating a patient. The method includes acquiring a plurality of radio frequency (RF) signals with an ultrasound transducer, each RF signal representing one or more return echoes from a scan line of a pulse-mode echo ultrasound scan. A position of the ultrasound transducer corresponding to each of the acquired RF signals is determined, and a plurality of contour lines generated from the plurality of RF signals. The method estimates a 3-D shape and position of an anatomical feature, such as a joint of patient based on the generated contour lines and corresponding ultrasound transducer positions. An apparatus, or computer includes a processor and a memory with instructions that, when executed by the processor, perform the aforementioned method. | 2021-12-09 |
20210378632 | ULTRASONIC IMAGING DEVICE, TREATMENT SUPPORT SYSTEM, AND IMAGE PROCESSING METHOD - In a transcatheter treatment support technique using a combination of a guide wire equipped with a photoacoustic technique and an ultrasonic imaging device, the ultrasonic imaging device estimates a front edge position of the guide wire using a difference between arrival times of photoacoustic waves arriving at an array of elements configuring an ultrasonic probe or a change of an image of the photoacoustic generation source, which depends on a distance of the photoacoustic generation source from an imaging region, and grasps a relationship between an imaging position and the front edge position of the guide wire using the estimation result. This enables visually grasping a relationship between a region (imaging region) from which an image is able to be obtained with reflective waves from a biological body with use of the ultrasonic probe and an insertion object present outside the region, particularly, the front edge of the guide wire. | 2021-12-09 |
20210378633 | METHOD AND APPARATUS TO PRODUCE ULTRASONIC IMAGES USING MULTIPLE APERTURES - A combination of an ultrasonic scanner and an omnidirectional receive transducer for producing a two-dimensional image from received echoes is described. Two-dimensional images with different noise components can be constructed from the echoes received by additional transducers. These can be combined to produce images with better signal to noise ratios and lateral resolution. Also disclosed is a method based on information content to compensate for the different delays for different paths through intervening tissue is described. The disclosed techniques have broad application in medical imaging but are ideally suited to multi-aperture cardiac imaging using two or more intercostal spaces. Since lateral resolution is determined primarily by the aperture defined by the end elements, it is not necessary to fill the entire aperture with equally spaced elements. Multiple slices using these methods can be combined to form three-dimensional images. | 2021-12-09 |
20210378634 | SYSTEMS AND METHODS FOR ASSOCIATING AND VERIFYING AN ASSOCIATION OF A TRANSDUCER WITH AN IMAGING DEVICE - The present disclosure describes system, application, and/or methods for enabling operation of a transducer probe with a medical imaging device. An example method includes the steps of retrieving a user identification code assigned to a user associated with an imaging device, retrieving a transducer identification code of a transducer probe from a memory of the transducer probe responsive to connecting the transducer probe to the imaging device, generating a temporary digital key based on the user identification code and the transducer identification code, retrieving a stored digital key from the memory of the transducer probe, verifying an association of the transducer probe including comparing the stored digital key with the temporary digital key, enabling operation of the transducer probe with the imaging device if the stored digital key matches the temporary digital key. | 2021-12-09 |
20210378635 | ULTRASOUND TRANSDUCER, ULTRASOUND ENDOSCOPE, AND MANUFACTURING METHOD OF ULTRASOUND TRANSDUCER - An ultrasound transducer includes: a flexible board configured to receive and output an electrical signal through a signal line; a plurality of piezoelectric devices that are electrically connected to the board and are aligned in a row, each piezoelectric device being configured to transmit and receive an ultrasound wave; a plurality of leads extending the signal line and protruding from an end portion of the board, each lead being electrically connected to the piezoelectric device in a curved manner; and a plurality of sheets that are arranged to prevent the leads from being in contact with each other, each sheet being provided on the lead and having an insulation property. | 2021-12-09 |
20210378636 | FIRST-ORDER ESTIMATION METHOD OF SHEAR WAVE VELOCITY - A first-order estimation method of shear wave velocity, includes the steps of demodulating entry data, and obtaining a complex angle value, matrix average, offset matrix, displacement matrix and shear wave velocity. According to the method, the main contour of the displacement curve is extracted by the quadrature decomposition of matrix, thereby improving the signal quality of the shear wave estimation. Unlike conventional method which needs estimating twice, the shear wave displacement curve can be estimated directly to reduce estimation errors and improve estimation efficiency. | 2021-12-09 |
20210378637 | ULTRASONIC DIAGNOSTIC APPARATUS AND ULTRASONIC PROBE - An ultrasonic diagnostic apparatus generates an ultrasonic image of a subject by using an ultrasonic probe, and the ultrasonic diagnostic apparatus includes: a transducer unit that is arranged in the ultrasonic probe and performs transmission and reception of ultrasonic waves; a stepping motor that is arranged in the ultrasonic probe and moves the transducer unit; a motor controller that sends a drive signal of a microstep drive method to the stepping motor; an encoder that is arranged in the ultrasonic probe, detects rotational motion of the stepping motor, and generates a detection signal having a pulse train shape depending on an amount of rotational displacement per unit time of the stepping motor; and a position data generator that generates high-resolution position data in which resolution of position data of the transducer unit obtained from the detection signal is increased. | 2021-12-09 |
20210378638 | ULTRASOUND CONTROL UNIT - An ultrasound control unit ( | 2021-12-09 |
20210378639 | Method for detecting antigens or antibodies to the antigens using EBC and EBC collection device - An exhaled breath condensate (EBC) collection device comprising two adjacent parts foldable together and apart from each other, a condensation zone to condense exhaled breath from a subject, the condensation zone being a third part provided between the two adjacent parts and connectable to cooling means arranged in each of the two parts being in cooling relationship with the condensation zone. There is also provided a method for detecting antigens or antibodies to the antigens, the method comprising collecting EBC from a subject using the EBC collection device, performing immunochromatographic testing (ICT) of the collected exhaled breath condensate, and interpreting the immunochromatographic testing results as follows: if the immunochromatographic testing results are positive, the antigens or antibodies to the antigens are detected, or if the immunochromatographic testing results are negative, the antigens or antibodies to the antigens are not detected. | 2021-12-09 |
20210378640 | Kit for the sampling of biological liquid such as urine and method utilizing such kit - The invention relates to a kit ( | 2021-12-09 |
20210378641 | DRUG DELIVERY AND BIOMARKER ACCESS DEVICES - This document describes devices for in vivo drug testing in the brain. This document also describes implantable devices for long-term drug delivery to the brain parenchyma, and for access to biomarkers from the parenchyma. | 2021-12-09 |
20210378642 | SAMPLE OBTAINED FROM THE PANCREATIC JUICE AND ANALYSIS THEREOF - Methods and techniques for obtaining enriched cell samples from an organ in a subject using an ultrasound contrast agent and insonating. Contiguous fragments of epithelia are obtained which are useful for subsequent histological analysis and for informing therapy and other medical considerations. | 2021-12-09 |
20210378643 | BREAKABLE SAMPLE COLLECTION SWAB - Provided herein, in some embodiments, are breakable swabs for sample collection. In some embodiments, the swabs may be used in rapid diagnostic tests to detect one or more target nucleic acid sequences (e.g., a nucleic acid sequence of one or more pathogens). In some embodiments, the pathogens are viral, bacterial, fungal, parasitic, or protozoan pathogens, such as SARS-CoV-2 or an influenza virus. The swab may include a stem portion for handling and a head portion for collecting and/or holding a sample. After sample collection, the head portion may be inserted into a reaction tube or any other sample-receiving device. The stem portion of the swab may then be separated or detached from the head portion along a breakable portion. | 2021-12-09 |
20210378644 | DEVICE AND METHODS FOR TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY - A robot-assisted approach for transrectal ultrasound (TRUS) guided prostate biopsy includes a hands-free probe manipulator that moves the probe with the same 4 degrees-of-freedom (DoF) that are used manually. Transrectal prostate biopsy is taken one step further, with an actuated TRUS manipulation arm. The robot of the present invention enables the performance of hands-free, skill-independent prostate biopsy. Methods to minimize the deformation of the prostate caused by the probe at 3D imaging and needle targeting are included to reduce biopsy targeting errors. The present invention also includes a prostate coordinate system (PCS). The PCS helps defining a systematic biopsy plan without the need for prostate segmentation. A novel method to define an SB plan is included for 3D imaging, biopsy planning, robot control, and navigation. | 2021-12-09 |
20210378645 | PERCUTANEOUS CATHETER DIRECTED INTRAVASCULAR OCCLUSION DEVICES - A collapsible medical device and methods for deploying the same are provided. The medical device includes a tubular metal fabric, which includes a plurality of braided metal strands and a proximal end and a distal end, the tubular metal fabric having a collapsed configuration for delivery and an expanded preset configuration for creating an occlusion of an opening. In the expanded preset configuration, the device has two expanded disk portions and a central portion, a first expanded disk portion and the central portion connected by a first reduced diameter portion, and a second expanded disk portion and the central portion connected by a second reduced diameter portion. Each of the first and second reduced diameter portions is smaller in diameter than both the two expanded disk portions and the central portion, and each of the first and second reduced diameter portions is recessed into the central portion. | 2021-12-09 |
20210378646 | MULTI-LAYER BRAIDED STRUCTURES FOR OCCLUDING VASCULAR DEFECTS - A collapsible medical device and associated methods of occluding an abnormal opening in, for example, a body organ, wherein the medical device is shaped from plural layers of a heat-treatable metal fabric. Each of the fabric layers is formed from a plurality of metal strands and the assembly is heat-treated within a mold in order to substantially set a desired shape of the device. By incorporating plural layers in the thus-formed medical device, the ability of the device to rapidly occlude an abnormal opening in a body organ is significantly improved. | 2021-12-09 |
20210378647 | ROLLABLE TISSUE SPECIMEN BAG WITH IMPROVED BRIM FOR TENTING - A tissue specimen retrieval bag assembly includes a tissue specimen bag having an open proximal end and a closed distal end, the proximal end including a cuff defined therein and extending therearound. A flexible bag brim is disposed within the cuff, the flexible bag brim transitionable between a first, collapsed configuration and a second, expanded configuration. The flexible bag brim includes a D-Shaped cross section configured to facilitate both furling the tissue specimen bag onto itself around the bag brim when the bag brim is disposed in the second, expanded configuration and securing the tissue specimen bag in a desired furled configuration. The flexible bag brim defines a cavity therein configured to facilitate compression thereof and to facilitate handling of the bag brim by a surgical instrument. | 2021-12-09 |
20210378648 | STEERABLE INSTRUMENT COMPRISING A TUBE ELEMENT - A steerable instrument has a proximal end and a distal end, a steering device ( | 2021-12-09 |
20210378649 | POWDER SPRAY DEVICE AND MEDICAL ADHESIVE EXCELLENT IN SELF-DECOMPOSABILITY AND ADHESIVENESS - A powder spray device includes a funnel member, a first three-way joint, an air-current supply tube, a discharge tube, a vibration motor, a bypass air-current tube, and a switching mechanism. The first three-way joint has a first opening connected to an outlet at a lower end of the funnel member. The air-current supply tube and discharge tube are respectively connected to second and third openings of the first three-way joint. The vibration motor is fixed onto an outer surface of a funnel body of the funnel member. The bypass air-current tube branches off from the air-current supply tube and is connected to the discharge tube. The switching mechanism switches from and to standby state, in which compressed gas is sent only through the bypass air-current tube, to and from spray-coating state, in which compressed gas is sent out through the air-current supply tube, and also through the bypass air-current tube. | 2021-12-09 |
20210378650 | BODY-CAVITY SHEET APPLYING DEVICE AND SHEET APPLYING METHOD - A sheet applying device, a sheet applying system, and a sheet applying method are provided. A first sheet applying system | 2021-12-09 |
20210378651 | A HAPTIC BASED SYSTEM FOR BONE GAP MEASUREMENT AND DISTRACTION - The present invention provides an instrument assembly that is expandable in steps for providing precise measurement of bone gap and distraction of bone in a controlled manner. It discloses a tool performing expandable Bi-Surface Mechanism to expand a bi-compartmental structure. The disclosed system is equipped with two active surfaces (Bottom base and a top plate) between which a force is applied to move the surfaces in relation to each other for providing precise measurement of bone gap and distraction of bone in a controlled manner. Additionally, the control mechanism of the present invention includes applying direct and/or measured/graduated separation force between the two surfaces and able to deliver haptic and sensor-based feedback to the surgeon for the critical ligament tensioning and balancing aspects of the procedure. | 2021-12-09 |
20210378652 | CAMK2D ANTISENSE OLIGONUCLEOTIDES AND USES THEREOF - The present disclosure relates to antisense oligonucleotides, which target CAMK2D mRNA in a cell, leading to reduced expression of CAMK2D protein. Reduction of CAMK2D protein expression is beneficial for the treatment of certain medical disorders, e.g., cardiovascular-related diseases or disorders. | 2021-12-09 |
20210378653 | SOFT SURGICAL CONSTRUCT AND METHOD OF USE FOR TISSUE REPAIR - Surgical constructs and methods of use for tissue repair, in which the surgical constructs include a soft fixation device formed of flexible material, the soft fixation device having a head portion formed of a bunching material for anchoring the soft fixation device in a bone tunnel, and a tail portion for pulling the soft fixation device into the bone tunnel. The surgical constructs include one ore repair flexible strands coupled to the head portion of the soft fixation device for engaging tissue to be repaired. | 2021-12-09 |
20210378654 | SYSTEM AND METHOD FOR REPAIRING SOFT TISSUE TEARS - A system and method for repairing soft tissue tears such as meniscal tears. The anchor system has a first implant connected to a length of suture. The length of suture is folded such that a tensioning limb extends from the first implant and a locking limb extends from the first implant. The anchor system also includes a second implant fixed to the locking limb and an adjustment mechanism in the length of suture between the first implant and the second implant. The tensioning limb is passed through the adjustment mechanism. This creates an adjustment loop in the length of suture extending from the adjustment mechanism through the first implant. The adjustment loop is a one-way adjustable loop for moving the first implant and second implant in relative position to each other. | 2021-12-09 |
20210378655 | TETHER LINE SYSTEMS AND METHODS FOR TONGUE OR OTHER TISSUE SUSPENSION OR COMPRESSION - Systems and methods of placing one or more suture loops into tissue, such as the base of the tongue, are described. A system can include a variable-thickness suspension line for suspending tissue, including a suture having a first thickness dimension; an elastomer surrounding a portion of the suture and defining a central segment of the suspension line having a second thickness dimension greater than the first thickness dimension, and at least one transition zone extending from the central segment of the suspension line to a lateral end of the suspension line, the transition zones having a thickness dimension that tapers from the second thickness dimension to the first thickness dimension. | 2021-12-09 |
20210378656 | KNOTLESS LATERAL ROW IMPLANT - An anchoring system includes an anchor including an anchor body and a distal member located at a distal end of the anchor body, the distal member having a suture receiving aperture; and an implant delivery device, comprising: a cannulated outer shaft, the cannulated outer shaft configured to engage a proximal end of the anchor body for driving the anchor into a bore; and an inner shaft slidably received in the cannulated outer shaft, wherein a distal end of the inner shaft is extendable distally beyond a distal end section of the cannulated outer shaft such that, when the cannulated outer shaft is engaging the proximal end of the anchor body, the distal end of the inner shaft is extendable through the anchor body to a distance beyond the distal end of the anchor body to engage a suture located within the suture receiving aperture, wherein the anchoring system is configured such that the suture can be tensioned at a location within the bore distal from the anchor body before the anchor body is implanted within the bore. | 2021-12-09 |
20210378657 | METHODS OF MAKING REINFORCED SOFT TISSUE GRAFTS WITH SUTURE LOOP/NEEDLE CONSTRUCTS - A method of reinforcing a biological construct according to an exemplary aspect of the present disclosure includes, among other things, attaching a suture loop/needle construct to a reinforcement material and stitching the reinforcement material to a biological construct to form a reinforced biological construct. The reinforcement material is attached to the suture loop/needle construct prior to approximating the reinforcement material to the biological construct. | 2021-12-09 |