48th week of 2017 patent applcation highlights part 10 |
Patent application number | Title | Published |
20170340722 | Novel immunization agents and methods of use - The present invention relates to a vaccine composition comprising an effective amount of a replication-competent controlled recombinant virus. Further encompassed are uses in immunization and methods of immunization employing compositions comprising a replication-competent controlled recombinant virus of the invention. | 2017-11-30 |
20170340723 | Process for Ready-to-Use PCV2/M.HYO Combination Vaccine - The present invention describes a process for the preparation of an antigen composition, which antigen composition can be used to prepare a ready-to-use vaccine for swine, for preventing or reducing infection by | 2017-11-30 |
20170340724 | ZIKA VIRUS RNA VACCINES - The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease. | 2017-11-30 |
20170340725 | COMBINATION PIV3/HMPV RNA VACCINES - The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines. | 2017-11-30 |
20170340726 | GENE-MODIFIED MEASLES VIRUS FOR TUMOR TREATMENT USE - It is an object of the present invention to provide a medicament or a pharmaceutical composition, which is effective for the treatment of various cancers. | 2017-11-30 |
20170340727 | A Rabies Composition Comprising Pika Adjuvant - The present disclosure provides a rabies composition comprising IPRV and PIKA adjuvant, and the pharmaceutical use thereof. The present disclosure also discloses a method for prophylaxis or therapeutic treatment of rabies virus infection, the method comprises a step of administering the rabies vaccine composition to a host. The rabies composition is more stable and safe, and is able to induce earlier and higher titers of neutralizing antibody. | 2017-11-30 |
20170340728 | Human Antibodies to Middle East Respiratory Syndrome - Coronavirus Spike Protein - The present invention provides monoclonal antibodies that bind to the Middle East Respiratory Syndrome—Coronavirus (MERS-CoV) spike protein, and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that bind to MERS-CoV spike protein. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing MERS-CoV activity, thus providing a means of treating or preventing MERS infection in humans. In some embodiments, the invention provides for a combination of one or more antibodies that bind to the MERS-CoV spike protein for use in treating MERS infection. In certain embodiments, the one or more antibodies bind to distinct non-competing epitopes comprised in the receptor binding domain of the MERS-CoV spike protein. | 2017-11-30 |
20170340729 | COMPOSITION COMPRISING PEDV ANTIGENS AND METHODS FOR MAKING AND USING THE COMPOSITION - Disclosed herein are embodiments of an immunogenic composition for porcine epidemic diarrhea virus, and a method for making the immunogenic composition. Also disclosed is a method for administrating the immunogenic composition to a subject in need thereof. The immunogenic composition comprises PEDV proteins and/or antigens from one or more strains of PEDV, and may additionally comprise proteins and/or antigens from one or more additional porcine pathogens, such as PRRSV. Additionally disclosed in a combination comprising a PEDV immunogenic composition as disclosed herein, and an immunogenic composition or other therapeutic composition directed toward an additional porcine pathogen. | 2017-11-30 |
20170340730 | CONTRUCTS FOR ENHANCING IMMUNE RESPONSES - Chimeric protein constructs including a herpesvirus glycoprotein D (gD) and a heterologous polypeptide that interact with herpes virus entry mediator (HVEM) and enhance and enhance an immune response against the heterologous polypeptide and methods for their use are provided. | 2017-11-30 |
20170340731 | NON-SPECIFIC DELAYED-TYPE HYPERSENSITIVITY RESPONSE TO TREAT HERPES SIMPLEX VIRUS INFECTION - A method is presented for treating herpes simplex virus (HSV) infection comprising: (a) locally administering a substance that induces a delayed type hypersensitivity (DTH) response to a patient at a site of an HSV lesion to induce a DTH response at the site of the lesion during one or more outbreaks of the HSV infection. | 2017-11-30 |
20170340732 | POLYMERIC IgA-TYPE RECOMBINANT ANTIBODY AND USE THEREOF - Provided are: a polymeric IgA-type recombinant antibody; a medicine containing this polymeric IgA-type recombinant antibody as an active ingredient; a method for producing this polymeric IgA type antibody, the method including the step of coexpressing an IgA-type antibody heavy-chain protein, an antibody light-chain protein, an antibody J-chain protein, and a secretory component protein within a single cell; and a method for improving the antigen-binding activity or neutralizing activity of this antibody, the method including the step of making an antibody into a polymeric IgA-type. | 2017-11-30 |
20170340733 | COMBINATION THERAPIES - Combination therapies are disclosed. The combination therapies can be used to treat or prevent cancerous conditions and/or disorders. | 2017-11-30 |
20170340734 | HUMAN MONOCLONAL ANTIBODIES AGAINST AXL - The present disclosure provides human monoclonal antibodies and antibody-drug conjugates against AXL and their use for the treatment of cancer. | 2017-11-30 |
20170340735 | Anti-TIGIT Antigen-Binding Proteins and Methods of Use Thereof - Provided herein are antigen-binding proteins (ABPs) that selectively bind to TIGIT and its isoforms and homologs, and compositions comprising the ABPs. Also provided are methods of using the ABPs, such as therapeutic and diagnostic methods. | 2017-11-30 |
20170340736 | PHOTOACTIVATABLE CAGED TAMOXIFEN AND TAMOXIFEN DERIVATIVE MOLECULES AND METHODS OF USE THEREOF - Provided herein are compositions containing photoactivatable caged tamoxifen and tamoxifen derivative molecules. Also provided are kits containing one of these compositions and a light source. Also provided are methods of optically inducing nuclear translocation of a fusion protein containing a mammalian estrogen receptor ligand binding domain in a eukaryotic cell and methods of optically inducing recombination in a eukaryotic cell that include contacting a eukaryotic cell with at least one of these compositions. Also provided are methods of treating breast cancer in a subject that include administering a photoactivatable caged tamoxifen or tamoxifen derivative molecule to a subject having breast cancer. | 2017-11-30 |
20170340737 | INTERLEUKIN -13 BINDING PROTEINS - The present invention encompasses IL-13 binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hIL-13 and neutralize hIL-13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-13 and for inhibiting hIL-13 activity, e.g., in a human subject suffering from a disorder in which hIL-13 activity is detrimental. | 2017-11-30 |
20170340738 | STABLE ACIDIC INSULIN FORMULATIONS - While the present invention is described herein with reference to illustrated embodiments, it should be understood that the invention is not limited hereto. Those having ordinary skill in the art and access to the teachings herein will recognize additional modifications and embodiments within the scope thereof. Therefore, the present invention is limited only by the claims attached herein. | 2017-11-30 |
20170340739 | PROGESTERONE FORMULATIONS HAVING A DESIRABLE PK PROFILE - This disclosure provides progesterone formulations, methods of using these formulations, and their related pharmacokinetic parameters. In particular embodiments, the formulations disclosed herein allow for a reduction in the amount of progesterone administered to a patient in need thereof, while still providing the benefits of a larger dosage amount. | 2017-11-30 |
20170340740 | LONG-ACTING POLYMERIC DELIVERY SYSTEMS COMPRISING OLANZAPINE AND A 5-HT3 RECEPTOR ANTAGONIST - Compositions comprised of olanzapine and a 5-HT3 receptor antagonist and a polyorthoester polymer are provided to provide extended release of the active agents. Also described are compositions comprising olanzapine and a polyorthoester. The compositions are effective for the prophylactic treatment or treatment of subjects at risk of or suffering from nausea and/or vomiting. The compositions are particularly useful for the prevention or treatment of acute, delayed, breakthrough or refractory chemotherapy induced nausea and vomiting (CINV). The CINV may result from, e.g., highly or moderately emetogenic cancer chemotherapy. The compositions are suitable for delivery via, e.g., intramuscular injection, intradermal injection, and subcutaneous injection. | 2017-11-30 |
20170340741 | Emulsions for Intrapulmonary Delivery - A therapeutic emulsion is provided comprising a perfluorocarbon emulsion and a therapeutic agent, such as tobramycin. Methods of making and using the emulsion are provided. A method of treating a lung infection is provided. | 2017-11-30 |
20170340742 | A METHOD FOR DELIVERING A SUBSTANCE INTO CELLS - A method for delivering a substance into cells, wherein the method comprises the following steps: a) providing the substance, wherein the substance comprises a cell-penetrating compound comprising a basic amino functional group, b) providing cells; and c) contacting the substance with the cells; wherein the method comprises the additional step of—adjusting a p H in an extracellular fluid to a p H of at least 7.7. | 2017-11-30 |
20170340743 | TOPICAL TETRACYCLINE COMPOSITIONS - A topical therapeutic hydrophobic breakable composition includes a carrier comprising (a) about 60% to about 99% by weight of at least one hydrophobic oil; (b) at least one viscosity-modifying agents selected from the group consisting of a fatty alcohol, a fatty acid and a wax; and (c) a tetracycline antibiotic, characterized in that at least part of the tetracycline antibiotic is suspended in the composition; the viscosity of the composition is at least about 30% higher than the viscosity of the carrier without the tetracycline antibiotic; and is higher than the viscosity of the hydrophobic oil and the tetracycline antibiotic without the viscosity modifying agents. The tetracycline is chemically stable in the composition for at least six months; wherein more than about 90% of the tetracycline has not broken down. The composition is packaged as a breakable foam that breaks easily upon application of shear force. | 2017-11-30 |
20170340744 | PHARMACEUTICAL COMPOSITION COMPRISING AMIDE DERIVATIVE INHIBITING THE GROWTH OF CANCER CELLS AND NON-METALLIC SALT LUBRICANT - Disclosed is a pharmaceutical composition comprising an amide derivative or a pharmaceutically acceptable salt thereof and a non-metallic salt lubricant, which can be used as an effective cancer cell-growth inhibitor owing to its enhanced storage stability with no quality changes over time. | 2017-11-30 |
20170340745 | NUCLEIC ACID COMPLEXES - The present invention relates to complexes of transcription factor decoys, their delivery to bacteria and their formulation. In particular, the present invention resides in an antibacterial complex comprising a nucleic acid sequence and one or more delivery moieties selected from quaternary amine compounds; bis-aminoalkanes and unsaturated derivatives thereof, wherein the amino component of the aminoalkane is an amino group forming part of a heterocyclic ring; and an antibacterial peptide. | 2017-11-30 |
20170340746 | PEGYLATED CARFILZOMIB COMPOUNDS - The present invention provides polymeric pegylated carfilzomib compounds, and pharmaceutically acceptable salts thereof, of Formula I | 2017-11-30 |
20170340747 | PROCESS FOR PRODUCING IRON (III) CASEIN N-ACETYL-ASPARTYLATED COMPLEXES AND USE THEREOF IN PHARMACEUTICAL COMPOSITIONS - The present invention generally relates to new process for the preparation of iron (III) casein N-acetyl-aspartylated complexes. The product obtainable according to the method of the present invention may be safely used to the general population or animals in the therapy of iron deficiency. The process of the invention includes the steps of:
| 2017-11-30 |
20170340748 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES - The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VI). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. | 2017-11-30 |
20170340749 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES - The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VII). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention. | 2017-11-30 |
20170340750 | ANTIBODY DRUG CONJUGATES HAVING DERIVATIVES OF AMATOXIN AS THE DRUG - There is disclosed derivatives of amanitin conjugated to a targeting antibody to form an ADC (antibody drug conjugate). | 2017-11-30 |
20170340751 | ARTIFICIAL MULTI-ANTIGEN FUSION PROTEIN AND PREPARATION AND USE THEREOF - Provided are an artificial multi-antigen fusion protein and a preparation method thereof. The fusion protein can effectively stimulate CD8+T and CD4+ T cell immunities, and can be applied to immunodiagnostics or serve as a prophylactic or therapeutic vaccine. | 2017-11-30 |
20170340752 | PYRROLOBENZODIAZEPINES AND CONJUGATES THEREOF - A conjugate of formula (A): Wherein Y is selected from formulae A1 and A2: Z | 2017-11-30 |
20170340753 | Conjugate Comprising Oxyntomodulin And An Immunoglobulin Fragment, And Use Thereof - The present invention relates to a conjugate comprising oxyntomodulin, an immunoglobulin Fc region, and non-peptidyl polymer wherein the conjugate being obtainable by covalently linking oxyntomodulin to immunoglobulin Fc region via non-peptidyl polymer, and a pharmaceutical composition for the prevention or treatment of obesity comprising the conjugates. The conjugate comprising oxyntomodulin and the immunoglobulin Fc of the present invention reduces food intake, suppresses gastric emptying, and facilitates lipolysis without side-effects, unlike native oxyntomodulin, and also shows excellent receptor-activating effects and long-term sustainability, compared to native oxyntomodulin. Thus, it can be widely used in the treatment of obesity with safety and efficacy. | 2017-11-30 |
20170340754 | Efficient delivery of therapeutic molecules in vitro and in vivo - Compositions are described for direct protein delivery into multiple cell types in the mammalian inner ear. The compositions are used to deliver protein(s) (such as gene editing factors) editing of genetic mutations associated with deafness or associated disorders thereof. The delivery of genome editing proteins for gene editing and correction of genetic mutations protect or restore hearing from genetic deafness. Methods of treatment include the intracellular delivery of these molecules to a specific therapeutic target. | 2017-11-30 |
20170340755 | INTRA-OPERATIVE IMAGING - The present invention relates to the use of a NIR fluorescent probe comprising an aza-bicycloalkane based cyclic peptide labelled with a Cy5.5 dye moiety in the fluorescence- guided surgery of pathologic regions and to an optical imaging method that comprises using this fluorescent probe for the identification and demarcation of tumor margins during the surgical resection. | 2017-11-30 |
20170340756 | PHARMACEUTICAL FORMULATION HAVING REVERSE THERMAL GELATION PROPERTIES FOR LOCAL DELIVERY OF NANOPARTICLES - The present invention refers to a pharmaceutical formulation for injection comprising fluorescent nanoparticles as in vivo diagnostics. The present invention relates to an injectable pharmaceutical formulation for human medicine and/or veterinary use, comprising 17% to 20% per weight of poloxamer 407 and 3%-15% per weight of poloxamer 188, 0.10 nM to 10.0 μM fluorescent nanoparticles and water or an aqueous buffer, wherein the pharmaceutical formulation is liquid at 4° C.-32° C. and forms a gel at about 37° C., their use as an in vivo marker and methods of their preparation. The inventive formulation is useful for local control and prevention of spreading/diffusion of nanoparticles, and thus allows full utilization of their quantum physics properties for example as a tool to enable surgical precision of tumor removal; even without tumor specific epitope binding antibodies. | 2017-11-30 |
20170340757 | TARGETED CONTRAST AGENTS COMPRISING A HYDRAZIDE FUNCTIONAL GROUP - Described herein is a contrast agent for administration to a subject. The contrast agent includes a targeting portion that includes a hydrazide functional group; a metal ion bound to a metal-complexable portion; and a linker joining the targeting portion and the metal-complexable portion of the contrast agent. The portion that is not bound to a metal ion localizes the contrast agent to necrotic tissue in the subject. | 2017-11-30 |
20170340758 | PET PROBES OF RADIOFLUORINATED CARBOXIMIDAMIDES FOR IDO-TARGETED IMAGING - F labeled IDO1 imaging constructs are constructed for positron emission tomography (PET). Synthetic methodology involves the coupling of a 1-fluoro-2-halo-4-aminobenzene and a 4-amino-N-hydroxy-1,2,5-oxadiazole-3-carboximidoyl chloride wherein at least one of the coupled compounds comprises an | 2017-11-30 |
20170340759 | RADIO-PHARMACEUTICAL COMPLEXES - The invention provides a method for the formation of a tissue-targeting thorium complex, said method comprising; a) forming an octadentate chelator comprising four hydroxypyridinone (HOPO) moieties, substituted in the N-position with a C | 2017-11-30 |
20170340760 | SYSTEM FOR DISINFECTING LARGER SCALE SPACES AND EQUIPMENT - The present disclosure relates generally to systems, devices and methods for disinfection of space and equipment. In particular, the present disclosure relates to systems, devices and methods, such as rolling enclosures, which use light sources, such as ultraviolet (UV) light, and more specifically UV-C light, to disinfect larger scale equipment or spaces. Systems and methods of the present disclosure are particularly useful in medical facilities for treating medical equipment or spaces, where the prevalence of pathogens requires frequent disinfecting. | 2017-11-30 |
20170340761 | Multi Wave Sterilization System - Ultraviolet radiation is directed within an area. The target wavelength ranges and/or target intensity ranges of the ultraviolet radiation sources can correspond to at least one of a plurality of selectable operating configurations including a virus destruction operating configuration and a bacteria disinfection operating configuration. Each configuration can include a unique combination of the target wavelength range and target intensity range. | 2017-11-30 |
20170340762 | FOOTWEAR SANITIZING SYSTEM - Introducing ultraviolet (UV) light to interior portions of footwear alters the environment inside a shoe or other footwear to destroy microorganisms or inhibit their growth. Visible light can also be used to prevent further microorganism growth. Introducing forced air flow through the footwear removes dampness in and thereby deodorizes the footwear. A preferred embodiment comprises an adjustable shoe tree equipped with a UV germicidal light source and electronic safeguards that prevent appreciable leakage of UV radiation outside the shoe. | 2017-11-30 |
20170340763 | METHOD OF DEMONSTRATING EFFICACY OF A MALODOR COUNTERACTANT PRODUCT - A method of demonstrating efficacy of a malodor counteractant product, the method comprising the steps of:
| 2017-11-30 |
20170340764 | SYSTEM AND METHOD FOR APPLICATION CONTROLLED FRAGRANCE GENERATION - A system and method for application controlled fragrance generation are disclosed. A particular embodiment includes: receiving a fragrance trigger from an application, the fragrance trigger being associated with a particular fragrance that corresponds to an event, action, image, sound, or gesture depicted in the application, determining a temperature needed to cause the particular fragrance to be emitted from a fragrance cartridge; and causing a thermal element to heat the fragrance cartridge to the determined temperature. | 2017-11-30 |
20170340765 | DISPENSING DEVICE - A dispensing device for release of a volatile material includes a base, a drive arm coupled to a pendulum based drive mechanism, and a refill coupled to the drive arm. The refill includes a support base, at least one flange, a substrate coupled with the at least one flange, and a use-up cue. | 2017-11-30 |
20170340766 | DEVICE FOR RELEASING VOLATILE SUBSTANCES - The device for releasing volatile substances comprises a support ( | 2017-11-30 |
20170340767 | DEVICE FOR RELEASING VOLATILE SUBSTANCES - A device for releasing volatile substances comprising a container containing the volatile substances located in a fixed position, and means for generating an air flow in order to release the volatile substances, the means for generating an air flow comprising a movable body, the movement of which generates the air flow; at least one magnet arranged on said movable body; and means for generating magnetic flux, the actuation of which causes the displacement of the movable body by means of the repulsion force between said at least one magnet in the movable body and the magnetic flux. The device enables energy consumption to be improved by using magnetically assisted periodic low-consumption actuation. | 2017-11-30 |
20170340768 | ABSORBENT ARTICLES HAVING ANTIMICROBIAL PROPERTIES AND METHODS OF MANUFACTURING THE SAME - According to one embodiment, an absorbent article includes a moisture-impervious outer layer, an inner layer substantially co-extensive with the outer layer, and an absorbent layer interposed between the outer layer and the inner layer. The inner layer is treated with at one least substance including dimethicone and/or at least one antimicrobial booster. The absorbent layer is treated with at least one antimicrobial agent. | 2017-11-30 |
20170340769 | NOVEL THERMORESPONSIVE ADHESIVE MATERIAL, METHOD OF MAKING THE MATERIAL AND METHODS OF USE - The present disclosure is directed to a thermoresponsive adhesive material. The material comprises a linear, phase-separated polymer having fluorinated polymer units and hydrophobic polymer units. The fluorinated polymer units and the hydrophobic polymer units are randomly ordered along the polymer. The hydrophobic polymer units include a first hydrophobic polymer unit and a second hydrophobic polymer unit. The first hydrophobic polymer unit is chosen from acrylate units or methacrylate units each substituted with one or more linear alkyl groups, linear alkenyl groups or a combination thereof, where at least one of the linear alkyl groups or alkenyl groups has 16 to 20 carbon atoms. The second hydrophobic polymer unit is chosen from acrylate units or methacrylate units each substituted with one or more linear alkyl groups, linear alkenyl groups or a combination thereof, where at least one of the linear alkyl or alkenyl groups of the second hydrophobic polymer unit has 5 to 14 carbon atoms. A peak adhesive strength of the thermoresponsive adhesive material is modifiable and reversible with a change in temperature. Methods of making thermoresponsive adhesive materials, methods employing thermoresponsive adhesive materials and self-adhesive objects that include thermoresponsive adhesive materials are also disclosed. | 2017-11-30 |
20170340770 | HYDRAULIC CEMENT-BASED IMPLANT MATERIAL AND USE THEREOF - The invention relates to implant materials that are based on hydraulic cements in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids and that react, when combined or when reacted with an aqueous liquid, to a solid in a cement-type initiation reaction. The invention also relates to the use of these materials as technical, medical-technical and/or pharmaceutical products, especially as bone cements, bone replacement materials, bone glues, dental filling materials and implantable active ingredient carriers. The implant materials according to the invention in the form of one or more pastes, suspensions or dispersions that contain mineral and/or organic and/or organomineral solids are formulated in an excipient liquid in such a manner that the pastes, suspensions or dispersions are stable in storage at normal conditions over a prolonged period of time and that they react, when combined with an aqueous liquid or when added to an aqueous liquid, in a cement-type initiation reaction and set to a solid. The excipient liquid of the mineral paste, suspension or dispersion is substantially water-free, and water immiscible or insoluble or hardly soluble in water in the chemical sense. | 2017-11-30 |
20170340771 | A BIOMATERIAL SCAFFOLD FOR REGENERATING THE ORAL MUCOSA - The present invention refers to a process for preparing a biomaterial scaffold said method comprising, (a) providing a hydrogel comprising a fibrin network and a polysaccharide network; (b) subjecting the hydrogel of step a) to a freeze-thawing process to physically crosslink the hydrogel; and (c) subjecting the physically cross-linked hydrogel obtained after conducting the step b), to a lyophilization. The invention also relates to the biomaterial scaffold obtainable by the process as defined above, as well said biomaterial scaffold for its use to partially or completely increase, restore or replace the functional activity of a diseased or damaged oral mucosa. | 2017-11-30 |
20170340772 | COLLAGEN SCAFFOLDS - Methods for preparing and using collagen extracts and collagen scaffolds are provided. Additionally methods and related kits for the repair of articular tissue using the collagen material are provided. | 2017-11-30 |
20170340773 | AUTO-POLYMERIZABLE PROSTHETIC MATERIAL AND POLYMERIZED, FRACTURE-TOUGH PROSTHETIC MATERIAL WITH INCREASED COLOUR STABILITY - The subject matter of the invention is an autopolymerisable two-component prosthetic base material and a method for its production comprising A) at least one liquid monomer component, and B) at least one powdered component, whereby the prosthetic material comprises in components (A) and/or (B) (i) at least one initiator or one initiator system for autopolymerisation, (ii) core-shell particles modified by an elastic phase, and (iii) at least one urethane (meth)acrylate. | 2017-11-30 |
20170340774 | POLETHYLENE GLYCOL HYDROGEL INJECTION - The present invention relates to a polyethylene glycol hydrogel injection, and, more particularly, to an injection to be administered into a joint (a synovial joint cavity) for the improvement of symptoms of arthritis by containing two separate buffer solutions, wherein a solution (1) contains a polyethylene glycol derivative with an electrophilic functional group and a buffer of pH 3.5 to 6, and a solution (2) contains a polyethylene glycol derivative with a nucleophilic functional group, hyaluronic acid, and a buffer of pH 7.5 to 11. The injection of the present invention is highly biocompatible and long-lasting in the joint, showing the efficacy of pain relief, cartilage protection, and inhibition of inflammation, thus offering the effective prevention and treatment of arthritis. | 2017-11-30 |
20170340775 | Settable Surgical Implants And Their Packaging - The present invention relates to settable compositions for use in surgery. The invention also provides related compositions, including surgical kits and packages, as well as methods of making and using the settable compositions. | 2017-11-30 |
20170340776 | CONTROLLABLE DEGRADATION, FILLING-TYPE COMPLEX BONE IMPLANT OF MULTIVARIANT AMINO ACID POLYMER-ORGANIC CALCIUM/PHOSPHORUS SALTS, AND PREPRATION METHOD THEREOF - The present invention relates to the controllable degradation, filling-type complex bone implant of multivariant amino acid polymer-organic calcium/phosphorus salts, as well as to the preparative method thereof. The complex bone implant is consisted of multivariant amino acid polymers and medically acceptable organic calcium/phosphorus salts, while the content of organic calcium/phosphorus salts is 20-90% based on the total mass of composite material; the multivariant amino acid polymer is polymerized by ε-aminocaproic acid and at least two other amino acids, in which the molar content of ε-aminocaproic acid is at least 50% of the total molar quantity of amino acid polymers, while the amounts of other amino acids are at least 0.5% of the total molar quantity of amino acid polymers. | 2017-11-30 |
20170340777 | Shape Memory Alloy Orthopedic Implant - Systems and methods discussed herein provide for fabricating orthopedic implants one or more shape-memory alloys including TiNi and TiNb and shape-setting the alloys to the geometry appropriate for the orthopedic implant. The shape-setting may include tuning the transformation temperature of the one or more alloys, and a single implant may comprise one or more alloys that may differ in composition, shape-setting process, or both. | 2017-11-30 |
20170340778 | COATING FORMULATIONS FOR SCORING OR CUTTING BALLOON CATHETERS - The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of the at least one drug being a limus drug and the at least one lipophilic antioxidant being butylated hydroxytoluene is excluded. | 2017-11-30 |
20170340779 | Compounds and Methods for Biofilm Disruption and Prevention - The invention relates to compounds, compositions, and methods for biofilm disruption and prevention. In particular, the invention relates to pharmaceutical compositions for the disruption of biofilm and prevention of biofilm in patients. The invention also relates to anti-biofouling compositions for the disruption of biofilm and prevention of biofilm on surfaces. The invention also relates to the removal of biological material from surfaces. The compositions of the invention include microbial deoxyribonucleases. | 2017-11-30 |
20170340780 | Degradable Iron-Base Alloy Support - A degradable iron-based alloy stem comprises an iron-based alloy substrate and a degradable polymer in contact with the surface of the substrate. The weight-average molecular weight of the degradable polymer is in the range of [1, 100]*10 | 2017-11-30 |
20170340781 | OLIGOFLUORINATED CROSS-LINKED POLYMERS AND USES THEREOF - The invention features oligofluorinated cross-linked polymers and their use in the manufacture of articles and coating surfaces. | 2017-11-30 |
20170340782 | Superhydrophobic Coating For Airway Mucus Plugging Prevention - A method for reducing mucus accumulation in an airway including disposing an implantable device within an airway, wherein the implantable device has a first end, a second end, and an inner surface defining a lumen extending from the first end to the second end; wherein at least a portion of the inner surface has a hydrophobic polymer coating thereon, wherein a polymer coating surface has dynamic water contact angles of 145 degrees or greater; and wherein the implantable device is constructed and arranged to maintain patency of the airway; wherein accumulation of mucus is reduced as compared to a similar implantable device without the hydrophobic portion of the inner surface. An implantable medical device having a superhydrophobic surface and a method of making an implantable medical device having a superhydrophobic surface are also provided. An implantable medical device having a micropatterned surface with enhanced adhesion to tissue, optionally in combination with other region(s) having a superhydrophobic surface and a method of making such a device. Methods and devices for prevention of bacterial adhesion to implanted medical devices. | 2017-11-30 |
20170340783 | CELL PROCESSING SYSTEM AND METHOD WITH PRELIMINARY PROCESS EVALUATION - A cell processing system includes a processor connectable to a source container filled with a biological fluid, the processor including a separator configured to separate the biological fluid from the source container into at least two streams according to a process including at least one process parameter, and a controller coupled to the processor and an input. The controller is configured to receive the at least one process parameter, to evaluate the process using the at least one process parameter before performing the process, and to carry out one or more actions based on the evaluation, such as providing an output estimate to the operator, preventing the process from being performed according to a comparison between a calculated condition and a control, or providing an error indication to the operator according to the calculated condition and a measured in-process condition. | 2017-11-30 |
20170340784 | WOUND MANAGEMENT - A method and apparatus are disclosed for delivering at least one agent to a wound site. The method includes the steps of providing a delivery tube having an outlet at a wound site, covering the wound site with a drape and introducing agent at an agent inlet port of the delivery tube. The agent passes along the delivery tube through the drape to the wound site. The agent can be a wide variety or mixture of fluids such as but not limited to pain relief medicament, anti-biotics, saline solution and/or hydrating fluid. | 2017-11-30 |
20170340785 | INTEGRATED AUTOTRANSFUSION BOWL AND FLUID LINE ORGANIZER - An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing. | 2017-11-30 |
20170340786 | An Implantable Hydraulic Displacement Actuator, System, Manufacturing And Methods Thereof - An implantable hydraulic displacement actuator comprising a biocompatible hydraulic displacement fluid for providing a force inside a human or animal body, wherein said hydraulic displacement actuator preferably is a linear hydraulic actuator for generating a cardiac movement. | 2017-11-30 |
20170340787 | CATHETER OF A HEART PUMP SHAPED FOR ANATOMIC FIT - A heart pump assembly, also referred to as catheter assembly, having a desired anatomical shape is provided. The catheter assembly can include a catheter and a cannula having a bend between a proximal portion and a distal portion. A resting shape of the catheter and the cannula can be selected to allow the distal cannula portion to be positioned at a desired angle relative to an anatomical plane (e.g., a plane of an aortic arch). In some embodiments, a packaging tray can be designed to set the catheter assembly in a desired resting shape. For example, the proximal cannula portion can be positioned at a first angle relative to the catheter, and the proximal cannula portion can be positioned at a second angle out of the plane of the packaging tray via one or more inserts. | 2017-11-30 |
20170340788 | MECHANICAL CIRCULATORY SUPPORT DEVICE WITH CENTRIFUGAL IMPELLER DESIGNED FOR IMPLANTATION IN THE DESCENDING AORTA - Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L/min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and/or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood. | 2017-11-30 |
20170340789 | CAVO-ARTERIAL PUMP - The present invention provides an intravascular right ventricular assist device, i.e., the cavo-arterial pump (CAP). Two prototypes of the CAP were developed, including a direct drive CAP and a magnetic drive CAP, demonstrating the feasibility of providing adequate pulmonary support and the feasibility of using axial magnetic couplings for contactless torque transmission from the motor shaft to the pump impeller. The magnetic drive CAP was able to operate up to 18.5 kRPM and produce a maximum flow rate of 1.35 L/min and a maximum pressure head of 40 mm Hg. | 2017-11-30 |
20170340790 | METHOD FOR OPERATING A PUMP DEVICE AND A PUMP DEVICE - A method may be provided for the operation of a pump device, which comprises at least one pump as well as a suction element which is connected to the at least one pump and which has a suction opening positioned in a cavity of a body of a patient that sucks a fluid by way of producing a reduced pressure in the suction element, wherein an acceleration is measured and monitored during the operation of the pump device, wherein the reduced pressure in the suction element is reduced at least for a limited reaction time period, given the occurrence of an acceleration variable which lies above a fixed threshold valve. A correspondingly configured pump device may be provided. | 2017-11-30 |
20170340791 | GUIDABLE INTRAVASCULAR BLOOD PUMP AND RELATED METHODS - An improved intravascular blood pump and related methods involving the broad inventive concept of equipping the intravascular blood pump with guiding features such that the intravascular blood pump can be selectively positioned at a predetermined location within the circulatory system of a patient. | 2017-11-30 |
20170340792 | A PORTABLE REGENERATIVE HAEMODIALYSIS SYSTEM AND A METHOD THEREOF - The present disclosure provides a portable haemodialysis system, comprising at least one haemodialyser configured to purify a biological sample. At least one fuel cell is fluidly connected to the at least one haemodialyser, the at least one fuel cell is adapted to receive oxygen and hydrogen from at least one oxygen and hydrogen storage units to generate energy and water. At least one energy reservoir is connected to the at least one fuel cell which is configured to store the energy generated in the at least one fuel cell. The water generated in the at least one fuel cell is supplied to the at least one haemodialyser for purification of the biological sample, and the energy stored in the at least one energy reservoir is used to power the haemodialyser during operation. | 2017-11-30 |
20170340793 | METHOD FOR PRODUCING DIALYZER COMPRISING A BUNDLE OF HOLLOW FIBERS AND METHOD FOR PRODUCING HOLLOW FIBER - A method for producing a hollow fiber pre-product for a dialysis membrane is disclosed. The dialysis membrane includes a distribution of the pore sizes which follows an exponential function such as an e-function. The inverse value of the exponential coefficient (K) is at least 30 nm | 2017-11-30 |
20170340794 | FILTRATION SYSTEM AND PROCESS FOR PERITONEAL DIALYSIS - Described are peritoneal dialysis systems and methods that involve the use of crossflow filtration of a used dialysate withdrawn from the peritoneal space of a patient. The filtration forms a retentate containing amounts of an osmotic agent and a permeate containing amounts of water and nitrogen-containing waste products of the patient. The retentate, or a fraction thereof, can be returned to the peritoneal space of the patient to return osmotic agent to the patient. The permeate, or a fraction thereof, can be discarded to discard nitrogen-containing waste products of the patient. | 2017-11-30 |
20170340795 | HEMOTRANSFILTRATION HOLLOW FIBER DEVICE - The present disclosure describes a device and method to clear solutes from a patient's blood while maintaining fluid balance. In some implementations, the device and method is used to assist the filtration functions of a patient's liver or kidney. The device includes a plurality of hollow fibers that pass through a sequence of alternating filtration chambers and infusion chambers. The filtration chambers filter the patient's blood while the infusion chambers rehydrate the filtered blood. | 2017-11-30 |
20170340796 | Infusion Line With A Facility To Promote Mixing Of An Infusion Solution With A Further Fluid, Apparatuses And Method - The present disclosure relates to an addition line for adding an infusion solution to a fluid, which flows in an extracorporeal blood circuit, wherein the addition line comprises a pressure release valve or a check valve. It further relates to an extracorporeal blood circuit, a blood treatment apparatus and a method using the addition line. | 2017-11-30 |
20170340797 | METHODS AND APPARATUS FOR EXTRACTING DOXORUBICIN FROM BLOOD AND MEASURING DOXORUBICIN IN BLOOD - Doxorubicin is extracted from blood using anionic material, such as a resin comprising sulfonated polystyrene divinylbenzene beads, and polyethersulfone membrane, or both. After exposing the resin and/or membrane to blood in order to remove doxorubicin therefrom, the doxorubicin maybe extracted from the resin and/or membrane by exposing the material to an extraction solution, sonicating the extraction solution to enhance release of the doxorubicin, and repeating the exposure and sonication in order to remove substantially all of doxorubicin from the resin. | 2017-11-30 |
20170340798 | Pressure Output Device For Extracorporeal Hemodialysis Machine - A pressure output device (POD) assembly for sensing fluid pressure in a fluid processing system, is provided. This POD assembly includes a shell defining a shell interior, and a movable diaphragm disposed in the shell interior and separating the shell interior into a flow-through chamber and a pressure sensing side. A sensor port is in fluid communication with the pressure sensing side. An inlet port and an outlet port are in fluid communication with the flow-through chamber. The inlet port and the outlet port define an inlet and an outlet, respectively, of a flow-through channel that passes through the flow-through chamber. A boss protrudes from the interior wall of the shell and extends into the flow-through channel to prevent occlusion of flow under different pressure conditions within the flow-through chamber. | 2017-11-30 |
20170340799 | SYSTEMS AND METHODS FOR PRIMING A FLUID CIRCUIT - Methods and systems for priming a disposable fluid circuit for the processing of a biological fluid are disclosed. The methods and systems allow for variable and configurable priming of the flow path(s) leading to one or more biological fluid source containers. | 2017-11-30 |
20170340800 | INFUSION SITE FOR IMPROVED MIXING OF FLUIDS - The invention relates to a blood line ( | 2017-11-30 |
20170340801 | BLOOD TREATMENT MACHINE HAVING ELECTRICAL HEARTBEAT ANALYSIS - A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump; a venous line; and a heartbeat evaluation system including (i) a first electrode coupled to the arterial line or to a patient, (ii) a second electrode coupled to the venous line, (iii) electronic circuitry communicating electrically with the first electrode and the second electrode to sense an electrical heartbeat signal generated by the patient, and (iv) signal processing configured to use the sensed heartbeat signal to calculate at least one of (a) heart rate, (b) respiration, (c) stroke volume, (d) cardiac output, or (e) central blood volume. | 2017-11-30 |
20170340802 | Method For Treating A Biological Fluid - A method for detoxifying a patient's blood by removing bilirubin from the patient's blood includes obtaining a batch of blood from the patient; controlling a pH of the blood so as to maintain the pH at approximately pH 7.4; controlling a temperature of the blood so as to maintain the temperature at approximately 37° C.; providing date pit-derived activated carbon; soaking the date pit-derived activated carbon within the blood for approximately 10-16 hours; and returning the detoxified blood to the patient. | 2017-11-30 |
20170340803 | METHOD FOR EXTRACORPOREAL REMOVAL OF PATHOGENIC MICROBE, AN INFLAMMATORY CELL OR AN INFLAMMATORY PROTEIN FROM BLOOD - The present invention relates to a method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from mammalian blood/use of a device comprising a carbohydrate immobilized on a solid substrate, said carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, for extracorporeal removal of said pathogenic microbe, inflammatory cell or inflammatory protein from mammalian blood/use of a carbohydrate having a binding affinity for a pathogenic microbe, an inflammatory cell or an inflammatory protein, wherein said carbohydrate is immobilized on a solid substrate, in the preparation of a device for treatment of a condition caused or aggravated by said pathogenic microbe, inflammatory cell or inflammatory protein and a method for treatment of a mammalian subject suffering from a condition caused or aggravated by a pathogenic microbe, an inflammatory cell or an inflammatory protein. | 2017-11-30 |
20170340804 | A System for Anal or Stomal Irrigation, and a Method for Predicting a Temperature of an Irrigation Liquid in a Reservoir of such System - A system for anal or stomal irrigation comprises a reservoir ( | 2017-11-30 |
20170340805 | Enema Adapter - An enema adapter attaches to a plurality of bottles, shower hoses, or water hoses as the fluid storage vessel or fluid source for body cavity flushing applications, such as enema, douching, or similar applications. The enema adapter directs the flow of water from the into the body cavity for medical or hygienic needs. The enema adapter includes discharge nozzle, a first mounting adapter, at least one discharge opening, and a nozzle cap. The discharge nozzle focuses and directs fluid flow from a fluid reservoir out through the at least one discharge opening into the user's body cavity. The discharge nozzle attaches to the first mounting adapter. The first mounting adapter secures the enema adapter to the fluid reservoir. | 2017-11-30 |
20170340806 | MEDICAL APPARATUS PACKAGE - A package for components of a medical apparatus comprising a plurality of panels defining a container having an interior space. A first component of the medical apparatus is disposed within the interior space. The first component of the medical apparatus comprises a medicament delivery device. At least one of said plurality of panels comprises a lid panel. The lid panel is secured in a closed position, in which it at least partially encloses the interior space, by a further component of the medical apparatus being bonded across an edge of the lid panel. Also disclosed is a medical apparatus comprising such a package with a container of medicament within the interior space of the container. | 2017-11-30 |
20170340807 | NEEDLE UNIT WITH A LOCKABLE NEEDLE SHIELD AND AN INJECTION DEVICE COMPRISING SUCH A NEEDLE UNIT - A needle unit ( | 2017-11-30 |
20170340808 | Kit Comprising a Medical Accessory Device and a Dummy Unit - The invention provides a kit comprising a medical accessory device and a dummy unit. The accessory device comprises first attachment means configured for releasable attachment of the accessory to co-operating second attachment means on an original device having an outer surface defining an original device space envelope. The dummy unit comprises a presentation surface on its external surface, a folded or rolled sheet, as well as dummy attachment means configured for releasable attachment of the accessory device to the dummy unit in co-operation with the first attachment means. By this arrangement the mounting of the accessory device on the original device can be demonstrated on the dummy unit in a simple and effective way. | 2017-11-30 |
20170340809 | THERMAL MANAGEMENT SYSTEM AND METHOD FOR MEDICAL DEVICES - A medical device includes a housing, a power supply, a thermally conductive mounting clamp, a heat shield, and at least one fastener. The housing includes a handle. The power supply is disposed within the housing. The thermally conductive mounting clamp is attached to an outer surface of the housing. The heat shield is disposed within the housing adjacent to the power supply. The heat shield is disposed against at least one interior surface of the handle. The at least one fastener passes through at least one opening in the housing and is in thermally conductive contact with the thermally conductive mounting clamp. Heat generated by the power supply is configured to dissipate from the power supply, through the heat shield, through the at least one fastener, and into the thermally conductive mounting clamp. | 2017-11-30 |
20170340810 | CONNECTING ARRANGEMENT FOR CONNECTING A SYRINGE TO A PUMP FOR DRUG INFUSION - A connecting arrangement for connecting a syringe to an electromechanical pump for drug infusion is provided. The syringe comprises a hollow cylindrical syringe body having a first, tapered open end for discharging the drug and a second open end. The syringe body is surrounded by connecting means arranged to firmly connect the syringe to the pump in a removable manner, an axially sliding plunger being housed in the syringe body for causing suction and injection of the drug through the first end. The pump comprises a pump body housing electromechanical members comprising a sliding rod partially projecting out of the pump body to cause sliding of the plunger within the syringe body of the syringe connected to the pump. The pump body being provided with connecting means arranged to receive in an engaging configuration the syringe body. The connecting means provided on the pump body comprise a cylindrical collar axially extending around the sliding rod and being internally provided with engaging elements, the collar defining a sealing end. The connecting means surrounding the syringe body comprise engaging elements arranged to cooperate with the engaging elements provided in the collar for firmly connecting the syringe to the pump in a removable manner. An annular flange extends radially around the syringe body. The flange cooperates with the sealing end defined in the collar to establish a tight sealing between the syringe body and the collar, whereby, when the syringe is attached to the pump, any moisture that may be present in the surrounding environment outside the pump and the syringe attached thereto does not penetrate into the pump body. | 2017-11-30 |
20170340811 | MECHANICAL INJECTION PUMP AND METHOD OF USE - A mechanical injection pump wearable by a user to deliver a first fluid and a second fluid, including: a pump body having a first fluid chamber to hold the first fluid and a second fluid chamber to hold the second fluid; a common connector having a first inlet, a second inlet, and a common outlet; a first fluid system including the first fluid chamber, a first button drive connected to the first fluid chamber, and first fluid delivery path between the first fluid chamber and the first inlet; and a second fluid system including the second fluid chamber, a second button drive connected to the second fluid chamber, and second fluid delivery path between the second fluid chamber and the second inlet. Force by the user on the button drive increases pressure within the fluid chamber to drive a predetermined volume of the fluid from the fluid chamber. | 2017-11-30 |
20170340812 | DRIP CHAMBER ASSEMBLY THAT FUNCTIONS IRRESPECTIVE OF ORIENTATION - A drip chamber assembly that functions irrespective of its orientation and in the presence of increased internal pressure is provided. | 2017-11-30 |
20170340813 | Intravenous Pole Base Having Tessellating Elements - An IV pole base is configured to couple in a tessellating manner to at least one other like IV pole base. The IV pole base can comprise a horizontal rectangular plate having four side edges and a given thickness (at least along the aforementioned side edges). This plate has a plurality of tessellating elements comprising each of a blank and a tab formed at each of the four side edges. The IV pole base further comprises a stabilizing thickening element disposed at a periphery of at least one of the tessellating elements to locally increase the thickness of the IV pole base beyond the thickness of the plate to thereby increase tessellation stability. The plate also includes an IV pole coupler formed centrally thereto, the IV pole coupler being configured to receive and hold an IV pole such that the IV pole extends outwardly perpendicularly to the plate. | 2017-11-30 |
20170340814 | IMPLANTABLE MEDICAL PUMP WITH PRESSURE SENSOR - The disclosure is directed to a pressure sensor of an implantable medical device. The pressure sensor may utilize detect fluid pressure based on a changing capacitance between two capacitive elements. The pressure sensor may define at least a portion of a fluid enclosure of the IMD. In one example, the pressure sensor has a self-aligning housing shape that occludes an opening in the pump bulkhead of the IMD. An operative surface of the pressure and the portion of the fluid enclosure may be formed of a corrosion resistant and/or biocompatible material. A first capacitive element of the pressure sensor may be a metal alloy diaphragm that deflects in response to external fluid pressure. A second capacitive element of the pressure sensor may be a metal coating on a rigid insulator sealed from the fluid by the diaphragm and a housing of the sensor. | 2017-11-30 |
20170340815 | ILLUMINATING MEDICAL INFUSION MANIFOLD - Disclosed are various embodiments for illuminated medical infusion including, for example, a medical infusion system which a medical infusion manifold that includes an integrated source of illumination for illuminating an illuminating medical infusion line. | 2017-11-30 |
20170340816 | SYSTEMS FOR SET CONNECTOR ASSEMBLY WITH LOCK - A set connector assembly for a fluid infusion device is provided. The set connector assembly includes a connector having a body. The body defines a graspable portion and a coupling portion, and the coupling portion is to be received within a portion of the fluid infusion device. The graspable portion has at least one locking tab to lock the connector to the fluid infusion device, and the graspable portion is movable relative to the body to move the connector between a first, locked position and a second, unlocked position relative to the fluid infusion device. | 2017-11-30 |
20170340817 | SYSTEMS FOR SET CONNECTOR ASSEMBLY WITH LOCK - A set connector assembly for a fluid infusion device is provided. The set connector assembly includes a connector having a body. The body defines a graspable portion and a coupling portion, and the coupling portion is to be received within a portion of the fluid infusion device. The graspable portion has at least one wing that defines at least one locking tab for locking the connector to the fluid infusion device. The graspable portion is movable relative to the body to move the connector between a first, locked position and a second, unlocked position relative to the fluid infusion device. | 2017-11-30 |
20170340818 | SYSTEMS FOR SET CONNECTOR ASSEMBLY WITH LOCK - A fluid infusion device is provided. The fluid infusion device includes a housing that includes a lock and a set connector assembly removably coupled to the housing to define a fluid flow path from the fluid infusion device. The set connector assembly includes a connector having a body that defines a graspable portion and a coupling portion. The coupling portion is receivable within the housing, and the graspable portion has at least one wing that defines a locking tab for engaging the lock. The at least one wing is movable relative to the body to disengage the locking tab with the lock. | 2017-11-30 |
20170340819 | MONITORING THE OPERATING HEALTH OF A FORCE SENSOR IN A FLUID INFUSION DEVICE - A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir. | 2017-11-30 |
20170340820 | APPARATUS AND SYSTEM FOR FLUID DELIVERY - An apparatus for delivering fluid from a fluid container comprises a housing to which a fluid container is attachable, a slider movably disposed in the housing and a resilient having a first end connected to the housing and a second end connected to the slider. Upon receiving an external force, the slider moves relative to the housing from a first position toward a second position to deform the resilient member from an original state to a deformed state, and upon release of the external force, the resilient member is allowed to resume to the original state to move the slider toward the first position to urge the slider against the fluid container to deliver fluid from the fluid container under a constant fluid flow rate. | 2017-11-30 |
20170340821 | INFUSION PUMP - An infusion pump is disclosed comprising control unit, container, actuation unit and detection unit. The container can store medicinal liquid for treating hypogonadotropic hypogonadism. The control unit can receive external control signal comprising infusion interval, concentration of medicinal liquid and dose of medicament for treating hypogonadotropic hypogonadism at each infusion. The control unit is configured to activate actuation unit based on infusion interval to cause medicinal liquid to flow out of container. The detection unit can detect output of medicinal liquid from container and feed it back to control unit. The control unit is configured to activate actuation unit based on dose at each infusion, concentration of medicinal liquid and fed-back output of medicinal liquid. According to the invention, sustained, automatic infusions of the medicament for treating hypogonadotropic hypogonadism are allowed without patient intervention. As a result, intelligent infusion of medicament is achieved in an easy and efficient manner. | 2017-11-30 |