48th week of 2014 patent applcation highlights part 49 |
Patent application number | Title | Published |
20140349833 | BLEND FOR THE PRODUCTION OF A REFRACTORY MATERIAL, A REFRACTORY MATERIAL, A METHOD FOR THE MANUFACTURE OF A REFRACTORY MATERIAL, AND USE OF A SUBSTANCE AS A SINTERING AID - The invention relates to a blend for the production of a sintered refractory material containing chromium oxide, a sintered refractory material containing chromium oxide, a method for the manufacture of a sintered refractory material containing chromium oxide and to a use of magnesium titanate. | 2014-11-27 |
20140349834 | COMPOSITION FOR FERROELECTRIC THIN FILM FORMATION, METHOD FOR FORMING FERROELECTRIC THIN FILM, AND FERROELECTRIC THIN FILM FORMED BY THE METHOD THEREOF - Disclosed is a composition for ferroelectric thin film formation which is used in the formation of a ferroelectric thin film of one material selected from the group consisting of PLZT, PZT, and PT. The composition for ferroelectric thin film formation is a liquid composition for the formation of a thin film of a mixed composite metal oxide formed of a mixture of a composite metal oxide (A) represented by general formula (1): (Pb | 2014-11-27 |
20140349835 | COMPOSITIONS AND PARTICLES CONTAINING CELLULOSIC FIBERS AND STABILIZED-AND/OR ACTIVATED-UREASE INHIBITORS, AS WELL AS METHODS OF MAKING AND USING THE SAME - The present invention relates to compositions containing stabilized and/or activated urease inhibitors, as well methods of making and using the same. | 2014-11-27 |
20140349836 | PROCESS FOR PREPARING NICKEL BASED CATALYSTS FOR SCR OF NATURAL GAS - The present invention relates to a method for preparing a nickel-based catalyst for steam carbon dioxide reforming (SCR) of natural gas using steam and carbon dioxide, more particularly to a method for preparing a nickel-based catalyst represented by Ni/η-Al | 2014-11-27 |
20140349837 | Method of Producing Fiber Catalyst and Fiber Catalyst Thereof - A method of producing a plurality of fiber catalyst is disclosed, the method includes the steps of: mixing a plurality of fiber material and a solvent to form a solution; putting the solution into a modeling container, to form at least one specific shape fiber body; applying a shaping process to the specific shape fiber body; and cutting or milling the specific shape fiber body to form a plurality of fiber catalyst. | 2014-11-27 |
20140349838 | METHOD FOR REGENERATION OF EXHAUST GAS TREATMENT CATALYST, AND EXHAUST GAS TREATMENT CATAYLST PRODUCED USING THE METHOD - A regenerated exhaust gas treatment catalyst regenerated by: a used catalyst coarse grinding step (S | 2014-11-27 |
20140349839 | MULTI-CAPILLARY MONOLITH MADE FROM AMORPHOUS SILICA AND/OR ACTIVATED ALUMINA - The invention relates to a monolithic porous material based on amorphous silica or activated alumina or on one of their mixtures, the material comprising substantially rectilinear capillary ducts that lie parallel to one another, and being intended to be used as packing in a chromatography column, characterised in that:
| 2014-11-27 |
20140349840 | AMMONIA OXIDATION CATALYST IN SCR SYSTEM - Disclosed herein is an ammonia oxidation catalyst for converting nitrogen oxides generated from a mobile source or fixed source into harmless nitrogen using ammonia as a reductant and preventing the formation of nitrogen oxides due to the oxidation of ammonia. The ammonia oxidation catalyst includes selective catalytic reductive zeolite sequentially impregnated with platinum and copper. | 2014-11-27 |
20140349841 | Catalyzed SCR Filter and Emission Treatment System - Provided is a catalyst article for simultaneously remediating the nitrogen oxides (NOx), particulate matter, and gaseous hydrocarbons present in diesel engine exhaust streams. The catalyst article has a soot filter coated with a material effective in the Selective Catalytic Reduction (SCR) of NOx by a reductant, e.g., ammonia. | 2014-11-27 |
20140349842 | PREPARATION METHOD OF POLYESTER SYNTHESIS COMPOSITE CATALYST - A method of preparing a composite catalyst for polyester synthesis includes the steps of: 1) sequentially dissolving a titanium compound, a silicon compound and a tin compound in an organic solvent; 2) adding a water solution of an acidic compound or of an alkaline compound in the compound from step 1) to cause hydrolysis thereof and collecting a precipitate, and washing the hydrolysis precipitate with a deionized water to obtain the composite catalyst. The catalyst is not only effective in polyester production polycondensation, but also has significant catalytic activity in esterification. The produced polyester chips all have a desirable hue. | 2014-11-27 |
20140349843 | Structured Cathode Catalysts for Fuel Cell Application Derived From Metal-Nitrogen-Carbon Precursors, Using Hierarchically Structured Silica as a Sacrificial Support - Methods for forming novel fuel cell catalysts are described. The catalyst has a physical structure that is the inverse image of a plurality of hierarchically structured sacrificial support particles. The particles may be formed independently and then infused with one or more transitional metallic salts and nitrogen carbon precursors, or the sacrificial support precursors, transitional metallic salts, and nitrogen carbon precursors may all be combined in such a way that a hierarchically structured sacrificial support with the infused transitional metallic salts and nitrogen carbon precursors is formed in a single step. The infused sacrificial support is then pyrolized, at least once, and the sacrificial support is removed, resulting in the catalyst. | 2014-11-27 |
20140349844 | SELECTIVE NICKEL BASED HYDROGENATION CATALYST AND THE PREPARATION THEREOF - A selective nickel-based hydrogenation catalyst and the preparation thereof, characterized in that: provided that the catalyst is weighed 100%, it comprises nickel oxide 14-20% as active component, lanthanum oxide and/or cerium oxide 2-8%, and VIB element oxide 1-8% as aids, 2-8% silica, 1-8% alkaline earth metal oxides, and alumina as the balance. The catalyst specific surface area is 60-150 m | 2014-11-27 |
20140349845 | PROCESS FOR PREPARING COBALT BASED CATALYSTS FOR FISCHER-TROPSCH SYNTHESIS - The present invention relates to a method for preparing a cobalt-based catalyst for Fischer-Tropsch synthesis, more particularly to a method for preparing a cobalt-based catalyst represented by Ir—Co/η-Al | 2014-11-27 |
20140349846 | KITCHENWARE WITH THERMOCHROMIC AND PHOTOCHROMIC INKS APPLIED IN HIGH VISIBILITY AREAS AS THERMAL STATE INDICATOR MECHANISM - Kitchenware comprising thermochromic and photochromic inks in zones of high visibility for the user are disclosed, as a mechanism to know by simple observation their thermal state (cold or hot), independently if said kitchenware is used outdoors (under sunlight exposure) or in enclosed areas. Said kitchenware corresponds to pots, frying pans, cooking pots, pressure cookers or any other kitchen utensil whose use may be outdoors or in enclosed areas and implies direct or indirect contact with a thermal energy source. Thermochromic and photochromic inks are applied in zones of the kitchenware where the user may easily see the color change during use, as in zones where there is no direct contact with food, which, depending on the type of kitchen utensil, may be in covers, knobs, grippers, handles, flame arrestors, regulator valves for pressure cookers, as in exterior walls that are not in direct contact with the thermal source. | 2014-11-27 |
20140349847 | PLANT TREATMENT METHOD - Plant propagation material treated with a carbonaceous material is provided. Such treated plant propagation material is useful in a method of inducing microbial interaction with the plant propagation material that confers a benefit on the plant propagation material. The method includes placing the treated plant propagation material in a growth medium containing endogenous soil microorganisms. | 2014-11-27 |
20140349848 | FUNGICIDAL 4-SUBSTITUTED-3--1,2,4-OXADIZOL-5(4H)-ONE DERIVATIVES - The present invention provides fungicidal 4-substituted-3-{phenyl[(heterocyclylmethoxy)imino]methyl}-1,2,4-oxadiazol-5(4H)-one derivatives of formula (I) | 2014-11-27 |
20140349849 | Active Substances for Increasing the Stress Defense in Plants to Abiotic Stress, and Methods of Finding Them - The invention relates to a method of finding compounds which increase the tolerance of plants to abiotic stress factors acting on this plant, such as, for example, temperature (such as chill, frost or heat), water (such as dryness, drought or anoxia), or the chemical load (such as lack of or excess of mineral salts, heavy metals, gaseous noxious substances) by increasing the expression of plant-endogenous proteins, and to the use of these compounds for increasing the tolerance in plants to abiotic stress factors. | 2014-11-27 |
20140349850 | Coated Dehydrated Microorganisms with Enhanced Stability and Viability - The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s) and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. The coating can be partially crystalline, the salt(s) in the coating having preferably a crystallinity degree of up to 60% once applied onto the dehydrated microorganism. The present invention also relates to liquid coating compositions, methods for coating and protecting a dehydrated microorganism. Finally, the present invention relates to a method for the preparation of food products, feed products, consumer healthcare products or agri-products as well as to a food product, feed product, a consumer healthcare product or an agri-product containing such coated dehydrated microorganisms. | 2014-11-27 |
20140349851 | Plant Growth Enhancing Mixture and Method of Applying Same - Plant growth enhancing mixture and method of selectively timing the application of same during the development of crop plants or other plants to positively augment cell number increase and cellular development of crop plants or other plants to enhance development and/or productivity of the economic portion of the crop plant or other plant. Application of the plant growth enhancing mixture at flowering enhances both weak flowers and normally strong flowers. The plant growth enhancing mixture and method of application have also been shown to impart varying disease resistance to the treated crop or other plants. The plant growth enhancing mixture and method of application also increases the depth and strength of rooting for greater access and transport of water and nutrients for growth and productivity of the crop plant. | 2014-11-27 |
20140349852 | METABOLIC CONTROL OF SEED GERMINATION - This invention provides Methods of conveniently controlling seed germination in genetically modified plants by the administration of a chemical modulator. The plant comprises a hormone-regulating gene placed under the control of a gene switch. | 2014-11-27 |
20140349853 | USE OF BENZOXABOROLES AS VOLATILE ANTIMICROBIAL AGENTS ON MEATS, PLANTS, OR PLANT PARTS - This invention is related to use of a volatile antimicrobial compound against pathogens affecting meats, plants, or plant parts. The volatile antimicrobial compounds provided include certain oxaborole compounds, for example benzoxaboroles. Delivery systems are provided to take advantage of the volatile nature of these antimicrobial compounds. Also combinations with a volatile plant growth regulator, for example 1-methylcyclopropene, are disclosed. | 2014-11-27 |
20140349854 | IRON-BASED SUPERCONDUCTING MATERIAL, IRON-BASED SUPERCONDUCTING LAYER, IRON-BASED SUPERCONDUCTING TAPE WIRE MATERIAL, AND IRON-BASED SUPERCONDUCTING WIRE MATERIAL - Provided is an iron-based superconducting material including an iron-based superconductor having a crystal structure of ThCr | 2014-11-27 |
20140349855 | T CELL RECEPTOR DISPLAY - A proteinaceous particle, for example a bacteriophage, ribosome or cell, displaying on its surface a T-cell receptor (TCR). The displayed TCR is preferably a heterodimer having a non-native disulfide bond between constant domain residues. Such display particles may be used for the creation of diverse TCR libraries for the identification of high affinity TCRs. Several high affinities are disclosed. | 2014-11-27 |
20140349856 | Neuroendocrine Tumors - The disclosure provides methods for the use of gene expression measurements to classify or identify neuroendocrine cancer in samples obtained from a subject in a clinical setting, such as in cases of formalin fixed, paraffin embedded (FFPE) samples. | 2014-11-27 |
20140349857 | METHOD FOR IN VITRO DIAGNOSIS OR PROGNOSIS OF COLON CANCER - The present invention relates to a method for in vitro diagnosis or prognosis of colon cancer, including a step of detecting at least one expression product of at least one HERV nucleic acid sequence, the use of said isolated nucleic acid sequences as a molecular marker/molecular markers, and a kit including at least one specific binding partner for at least one expression product of the HERV nucleic acid sequences. | 2014-11-27 |
20140349858 | AMPLIFICATION OF A SEQUENCE FROM A RIBONUCLEIC ACID - The present invention relates to methods and compositions for tagging, amplifying, purifying, and or characterizing of ribonucleic acid (RNA) in a sample. In particular, methods are provided for preparing RNA from a sample for subsequent analysis. | 2014-11-27 |
20140349859 | DETECTION OF TARGET NUCLEIC ACIDS USING HYBRIDIZATION - The present invention provides detection systems and methods for detection of loci and genomic regions in a sample, including mixed samples, using hybridization to an array. | 2014-11-27 |
20140349860 | IDENTIFYING PEPTIDES AT THE SINGLE MOLECULE LEVEL - The present invention relates to methods for identifying amino acids in peptides. In one embodiment, the present invention contemplates labeling the N-terminal amino acid with a first label and labeling an internal amino acid with a second label. In some embodiments, the labels are fluorescent labels. In other embodiments, the internal amino acid is lysine. In other embodiments, amino acids in peptides are identified based on the fluorescent signature for each peptide at the single molecule level. | 2014-11-27 |
20140349861 | Method for Distinguishing Biological Material Products - A method for encoding and identifying biological materials is disclosed. The method may include encoding and identifying plants from which controlled substances may be derived and other materials for which movement and distribution may need to be tracked. The biological material may be first encoded using DNA oligomers. A spray method or the use of an encoded substrate, both using these DNA oligomers for encoding the biological material, may be employed. The biological material, or a part of the biological material, may be first encoded by atomizing a solution containing DNA oligomers onto it and then dried by an appropriate method. Thereafter, the part of the encoded biological material, or the nitrocellulose substrate, may be dissolved with a buffer solution for extracting the DNA oligomers. Then, the dissolved solution may be used for generating a barcode by a suitable detection scheme. | 2014-11-27 |
20140349862 | METHODS AND COMPOSITIONS FOR THERAPEUTIC DRUG MONITORING AND DOSING BY POINT OF CARE PHARMACOKINETIC PROFILING - Disclosed are methods and kits for pharmacokinetic profiling employing point-of-care or point of service self-sampling and allowing for dosage adjustments based on the pharmacokinetic profiles. | 2014-11-27 |
20140349863 | Assay for Diagnosing Streptococcus Pneumoniae - Assays for detecting anti-streptococcal antibodies in biological samples using one or more streptococcal antigens are described herein. Various combinations of antigens may be used in the assays. For example, one or more of Ply, PhtD, PhtE, LytB and PcpA may be utilized. Additional streptococcal antigens may also be used. The assays may also be used in combination with assays that detect streptococcal nucleic acids. | 2014-11-27 |
20140349864 | METHODS AND COMPOSITIONS OF MOLECULAR PROFILING FOR DISEASE DIAGNOSTICS - The present invention relates to compositions, kits, and methods for molecular profiling and cancer diagnostics, including but not limited to gene expression product markers, alternative exon usage markers, and DNA polymorphisms associated with cancer. In particular, the present invention provides molecular profiles associated with thyroid cancer, methods of determining molecular profiles, and methods of analyzing results to provide a diagnosis. | 2014-11-27 |
20140349865 | DRUG SELECTION FOR BREAST CANCER THERAPY USING ANTIBODY-BASED ARRAYS - The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of components of signal transduction pathways derived from use of the invention can be used for cancer diagnosis, prognosis, and in the design of cancer treatments. | 2014-11-27 |
20140349866 | NEW TH-17 DIFFERENTIATION MARKERS FOR ROSACEA AND USES THEREOF - Methods are described for using genes crucial in TH17 differentiation, IL-12Rbeta 1/IL-23R, CCR6, BATF, AHR, STAT3 and IRF4 as new markers for rosacea. Also described, are methods of their use to diagnose rosacea, to screen inhibitors of Th17 differentiation. In particular, method are described for inhibiting at least one of these genes and using the screened inhibitors in rosacea treatment. | 2014-11-27 |
20140349867 | SYSTEM AND METHOD FOR CAPTURING AND ANALYZING CELLS - A system and method for capturing and analyzing a set of cells, comprising: an array including a set of parallel pores, each pore including a chamber including a chamber inlet and a chamber outlet, and configured to hold a single cell, and a pore channel fluidly connected to the chamber outlet; an inlet channel fluidly connected to each chamber inlet of the set of parallel pores; an outlet channel fluidly connected to each pore channel of the set of parallel pores; a set of electrophoresis channels fluidly coupled to the outlet channel, configured to receive a sieving matrix for electrophoretic separation; and a set of electrodes including a first electrode and a second electrode, wherein the set of electrodes is configured to provide an electric field that facilitates electrophoretic analysis of the set of cells. | 2014-11-27 |
20140349868 | METHODS AND COMPOSITIONS FOR MONITORING AND RISK PREDICTION IN CARDIORENAL SYNDROME - The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods and compositions selected to monitor cardiorenal syndrome using assays that detect NGAL, preferably together with assays that detect natriuretic peptides such as BNP. Such methods and compositions can provide early indications of a deterioration in cardiorenal syndrome status, including prognosis regarding mortality and worsening renal function. | 2014-11-27 |
20140349869 | METHODS OF DETECTING LUNG CANCER - Methods of detecting lung cancer, such as non-small cell lung cancer, including squamous cell carcinoma and adenocarcinoma, are provided. Methods of detecting changes in the levels of one or more small RNAs associated with lung cancer are also provided. Compositions and kits are also provided. | 2014-11-27 |
20140349870 | SELF-REGULATING CHEMO-MECHANO-CHEMICAL SYSTEMS - A chemo-mechano-chemical (C | 2014-11-27 |
20140349871 | REAL-TIME ANALYSIS FOR CROSS-LINKED PEPTIDES - Disclosed herein are methods for large-scale, high-throughput identification of protein-protein interactions and the topologies thereof under physiologically relevant conditions. In one aspect, the disclosure provides methods for identifying one or a plurality of interacting peptides within a biological system comprising obtaining a population of proteins cross-linked with a cleavable protein interaction reporter (PIR) cross-linker, cleaving the PIR crosslinker to produce released peptides and cleaved reporter ions, and analyzing the population of released peptides to identify interacting peptides. Also disclosed are methods for identifying candidate drug compounds, as well as methods of data processing and visualization of protein-protein interactions. | 2014-11-27 |
20140349872 | Systems and Methods for Immunosorbent Assay for Single and Multiple Analytes - Systems and methods for minimizing or eliminating steps in immunosorbent assays for single and multiple analytes by eliminating the need to attach target molecules to test well and the need to remove unbound antibodies through rinsing. Immunosorbent assay (ISA) is utilized for a single analyte and includes the step of mixing the immunologic molecules with the sample and detection. Immunosorbent assay for multiple analytes for testing a plurality of analytes in a single well is disclosed using a modified ISA test wherein different tags are attached to different antibody pairs. Alternate embodiments use multiple types of scavenger antigens with corresponding elimination of the need for scavenger antibodies. Various types of test wells are disclosed for rapid and simultaneous testing of fluids for a plurality of components and methodology for continuous immunosorbent assay. Method for immunosorbent assay of an analyte object having a plurality of distinct target antigens is also disclosed. | 2014-11-27 |
20140349873 | Methods of Producing Competitive Aptamer FRET Reagents and Assays - Methods are described for the production and use of fluorescence resonance energy transfer (FRET)-based competitive displacement aptamer assay formats. The assay schemes involve FRET in which the analyte (target) is quencher (Q)-labeled and previously bound by a fluorophore (F)-labeled aptamer such that when unlabeled analyte is added to the system and excited by specific wavelengths of light, the fluorescence intensity of the system changes in proportion to the amount of unlabeled analyte added. Alternatively, the aptamer can be Q-labeled and previously bound to an F-labeled analyte so that when unlabeled analyte enters the system, the fluorescence intensity also changes in proportion to the amount of unlabeled analyte. The F or Q is covalently linked to nucleotide triphosphates (NTPs), which are incorporated into the aptamer by various nucleic acid polymerases, such as Taq or Deep Vent Exo | 2014-11-27 |
20140349874 | DIAGNOSTIC POLYMORPHISMS FOR CARDIAC DISEASE - One or more polymorphisms, including single nucleotide polymorphisms (SNPs), or combinations thereof, for diagnosis of cardiac disease, such as heart failure and atrial fibrillation. | 2014-11-27 |
20140349875 | METHOD FOR THE IN VITRO DIAGNOSIS OR PROGNOSIS OF TESTICULAR CANCER - A method for in vitro diagnosis of testicular cancer includes (i) obtaining a biological sample from a patient suspected of having testicular cancer, (ii) performing an assay to determine the methylation status of CpG dinucleotides in a genomic DNA target sequence, the DNA target sequence being the 5′ LTR U3 promoter sequence of the ERVWE1 locus, optionally further including an activator sequence directly upstream of the 5′ LTR U3 promoter sequence, and (iii) diagnosing the patient with testicular cancer when the DNA target sequence is hypomethylated as compared to a methylation status indicative of the absence of testicular cancer. | 2014-11-27 |
20140349876 | SUGARCANE-STALK=SUGAR-CONTENT-RELATED MARKER AND THE USE THEREOF - According to the present invention, a sugarcane-stalk-sugar-content-related marker linked to a sugarcane quantitative trait is provided. Such marker is a sugarcane-stalk-sugar-content-related marker, which comprises a continuous nucleic acid region existing in a region sandwiched between the nucleotide sequence shown in SEQ ID NO: 1 and the nucleotide sequence shown in SEQ ID NO: 8 or a region sandwiched between the nucleotide sequence shown in SEQ ID NO: 9 and the nucleotide sequence shown in SEQ ID NO: 16. | 2014-11-27 |
20140349877 | METHODS AND COMPOSITIONS FOR DIAGNOSING NEURODEGENERATIVE DISEASE - Methods and compositions for detecting and diagnosing Parkinson's disease are disclosed. | 2014-11-27 |
20140349878 | PACLITAXEL RESPONSE MARKERS FOR CANCER - Cancer marker sets consisting of particular genes differentially expressed in tumours provide improved accuracy of predicting effectiveness of paclitaxel or paclitaxel-like drug treatment against a cancer. These sets are further useful for screening drug candidates for paclitaxel-like cancer treatment activity. The cancer marker sets may be used in a clinical setting to provide information about the likelihood that a cancer patient would or would not respond to paclitaxel or paclitaxel-like drug treatment. | 2014-11-27 |
20140349879 | METHOD FOR DETECTING NUCLEOTIDE MUTATION, AND DETECTION KIT - Provided are a detection method and detection kit for detecting a nucleotide mutation simply, with highly sensitivity and high specificity, which allow a plurality of samples to be simultaneously detected in a single measurement. The detection method includes the steps of: amplifying a nucleic acid to be tested to obtain a DNA amplification product; subjecting the DNA amplification product, a first nucleic acid probe having a region complementary to a first region of the DNA amplification product, a second nucleic acid probe having a region complementary to a second region of the DNA amplification product, and a plurality of kinds of signal amplification probes to be used in a PALSAR method to a reaction to form a complex for detection including a probe polymer; and detecting the probe polymer bound in the complex for detection to detect the presence or absence of a mutation in a nucleotide mutation site of the DNA amplification product, the first region of the DNA amplification product including the nucleotide mutation site, the nucleotide mutation site being located at a portion other than both end portions of the first region, the second nucleic acid probe having a base sequence identical to part or all of the base sequence of one of the signal amplification probes. | 2014-11-27 |
20140349880 | NOVEL ANTIBIOTIC PREPARATION METHOD AND PLATFORM SYSTEM BASED ON SAME - Provided are a novel antibiotic preparation method and platform system based on the method, belonging to a novel drug development method. The method is based on a fixed structural formula: F—R, wherein F is an effect area, and R is an identification area. At the prior art level, the present invention can quickly develop a specific novel antibiotic for most pathogenic microorganisms or biological cells. Also provided is a platform for implementing the method, ensuring that the novel antibiotic is developed in an efficient streamlined process. | 2014-11-27 |
20140349881 | BIOMARKERS AND PARAMETERS FOR PREECLAMPSIA - The application discloses new test panels comprising biomarkers and clinical parameters, for the prediction, diagnosis, prognosis and/or monitoring of hypertensive disorders of pregnancy and particularly preeclampsia; and related methods, uses, kits and devices. | 2014-11-27 |
20140349882 | METHOD FOR THE DIAGNOSIS OF ROSACEA - A method is described for the diagnosis of rosacea. The method can include a step of measuring the expression of at least one peptide from the galanin family in a sample of biological fluid from a patient. Also described, is a related diagnostic kit. | 2014-11-27 |
20140349883 | MONITORING TRANSFORMATION OF FOLLICULAR LYMPHOMA TO DIFFUSE LARGE B-CELL LYMPHOMA BY IMMUNE REPERTOIRE ANALYSIS - The invention is directed to a method of prognosing in an individual a transformation from follicular lymphoma to diffuse large B-cell lymphoma (DLBCL) by measuring changes and/or lack of changes in certain groups of related clonotypes, referred to herein as “clans,” in successive clonotype profiles of the individual. A clan may arise from a single lymphocyte progenitor that gives rise to many related lymphocyte progeny, each possessing and/or expressing a slightly different immunoglobulin receptor due to somatic mutation(s), such as base substitutions, inversions, related rearrangements resulting in common V(D)J gene segment usage, or the like. A higher likelihood of transformation from follicular lymphoma to DLBCL is correlated with the persistence of clans in successive clonotype profiles whose clonotype membership fails to undergo diversification over time. | 2014-11-27 |
20140349884 | Synthetic Mammalian Neuromuscular Junction and Method of Making - A method for forming neuromuscular junctions includes forming functional neuromuscular junctions between motoneurons and muscle cells by co-culturing one or more human motoneurons and one or more human muscle cells in a substantially serum-free medium. A synthetic mammalian neuromuscular junction includes a human motoneuron functionally linked to a human muscle cell in a substantially serum-free medium. An artificial substrate may be used to support the one or more neuromuscular junctions. | 2014-11-27 |
20140349885 | ENHANCEMENT OF SENSITIVITY AND SPECIFICITY OF KETOSTEROIDS AND KETO OR ALDEHYDE CONTAINING ANALYTES - A method, a labeling reagent, sets of labeling reagents, and labeling techniques are provided for the relative quantitation, absolute quantitation, or both, of ketone or aldehyde compounds including, but not limited to, analytes comprising steroids or ketosteroids. The analytes can be medical or pharmaceutical compounds in biological matrices. Methods for labeling, analyzing, and quantifying ketone or aldehyde compounds are also disclosed as are methods that also use mass spectrometry. | 2014-11-27 |
20140349886 | PRIMERS AND KITS FOR COLONY MULTIPLEX PCR FOR THE DETECTION OF CLASS A, B, C, AND D BETA-LACTAMASE GENES AND METHODS OF USING THEREOF - The present invention provides kits and primers for colony multiplex PCR for the detection of class A, B, C, and D β-lactamase genes. The rapid detection of bla genes by using the kits and primers according to the present invention allows appropriate prescribing of antibiotics, which can reduce patient mortality and minimize antibiotic resistance. The present invention provides kits and primers for a rapid and accurate molecular method to overcome (a) to detect all clinically-important bla genes and (b) to explain phenotypic tests' results well by using 54 primer pairs, which are designed through novel and elaborate optimization processes. With perfect specificity and sensitivity in 172 control strains and 403 clinical strains, the present invention provides prompt and clinical application to the identification of all bla genes in bacterial pathogens. | 2014-11-27 |
20140349887 | Non-Emulsion Methods And Masked Biomolecules - The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array. | 2014-11-27 |
20140349888 | Substrates, Peptide Arrays, and Methods - Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. | 2014-11-27 |
20140349889 | FORMATION OF A SUPRA-MONOLAYER NANOPATTERN AND ITS USES - The present disclosure discloses a method to prepare a supra-monolayer nanopattern and its uses. | 2014-11-27 |
20140349890 | Multiplex Amplification Methods - Compositions and methods for amplifying selected polynucleotides, including DNA and RNA, particularly in multiplex amplification reactions using common primers amplification. Generally, methods of the invention employ multiple steps such as template-specific hybridization, a linear amplification, partial degradation of nucleic acid, and ligation. At the end of the process the sequences of selected polynucleotides are flanked by the common sequences which can be used for exponential amplification using common primers. In some aspects the polynucleotides are associated with a barcode and the presence of the barcode is detected to measure the amount of the polynucleotide. | 2014-11-27 |
20140349891 | Preparation of Templates for Nucleic Acid Sequencing - The invention relates to methods of generating templates for a nucleic acid sequencing reaction which comprise:
| 2014-11-27 |
20140349892 | APPARATUS FOR THE PROCESSING OF SINGLE MOLECULES - The invention relates to an apparatus( | 2014-11-27 |
20140349893 | LABELING OF IMMOBILIZED PROTEINS USING DIPYRROMETHENEBORON DIFLUORIDE DYES - The invention describes methods for labeling or detecting of immobilized poly(amino acids), including peptides, polypeptides and proteins, on membranes and other solid supports, using fluorescent dipyrrometheneboron difluoride dyes. Such immobilized poly(amino acids) are labeled or detected on blots or on arrays of poly(amino acids), or are attached to immobilized aptamers. | 2014-11-27 |
20140349894 | NANOFLUIDS AND METHODS OF USE FOR DRILLING AND COMPLETION FLUIDS - Nanomaterial compositions are useful for applications in drilling and completion fluids as enhancers of electrical and thermal conductivity, emulsion stabilizers, wellbore strength improvers, drag reduction agents, wettability changers, corrosion coating compositions and the like These nanomaterials may be dispersed in the liquid phase in low volumetric fraction, particularly as compared to corresponding agents of larger size. Nanofluids (fluids containing nano-sized particles) may be used to drill at least part of the wellbore. Nanofluids for drilling and completion applications may be designed including nanoparticles such as carbon nanotubes. These fluids containing nanomaterials, such as carbon nanotubes, meet the required rheological and filtration properties for application in challenging HPHT drilling and completions operations. | 2014-11-27 |
20140349895 | INVERT EMULSION DRILLING FLUID CONTAINING A HYGROSCOPIC LIQUID AND A POLYMERIC SUSPENDING AGENT - An invert emulsion drilling fluid comprises: an external phase, wherein the external phase of the drilling fluid comprises a hydrocarbon liquid; an internal phase, wherein the internal phase of the drilling fluid comprises a hygroscopic liquid; and a suspending agent, wherein the suspending agent is a polymer comprising urea linkages or urea and urethane linkages. The hygroscopic liquid comprises a salt and a suitable solvent or comprises an alcohol. The drilling fluid can exclude an organophilic clay or organophilic lignite. A method of using the invert emulsion drilling fluid comprises: introducing the drilling fluid into at least a portion of a subterranean formation. | 2014-11-27 |
20140349896 | PROPPANT AND METHOD OF PROPPING A SUBTERRANEAN FRACTURE - A proppant for use in fracturing a subterranean formation is characterized by specific mean particle size, particle size standard deviation, and aspect ratio. The proppant is prepared from a thermoplastic composition that includes specific amounts of a polyamide and a poly(phenylene ether). The proppant is useful for propping a fracture in a subterranean formation. | 2014-11-27 |
20140349897 | Treatment Fluids with Non-Oxidizer Class Inorganic Peroxide Polymer Breakers and Methods of Use Thereof - A treatment fluid composition for treating a subterranean formation penetrated by a well bore is formed from an aqueous fluid, a hydratable polymer and an inorganic peroxide breaking agent, which is classified as a stable, non-oxidizer according to UN standards but which retains oxidizing properties as measured by the content of available oxygen. A method of treating a subterranean formation penetrated by a well bore may also be performed by forming a treatment fluid from an aqueous hydrated polymer solution. This is combined with a stable, inorganic peroxide breaking agent. The treating fluid is then introduced into the formation. An optional crosslinking agent capable of crosslinking the polymer may also be included. | 2014-11-27 |
20140349898 | SLIDING COMPONENT - A swash plate type compressor is arranged with a plurality of semispherical shoes and a disc shaped swash plate. A resin coating having a honeycomb structure is formed on a surface and a rear surface (sliding surface) of the swatch plate which slides with the shoe. An edge part (top end) of each of the multiple cylinder bodies which forms the resin coating layer are at the same plane and forms a sliding surface which slides with the shoe. In addition, an interior space of each cylinder body forms a storage part of a lubricant and a container part for foreign objects. | 2014-11-27 |
20140349899 | DRY LUBRICANT FOR CONVEYING CONTAINERS - The passage of a container along a conveyor is lubricated by applying to the container or conveyor a mixture of a water-miscible silicone material and a water-miscible lubricant. The mixture can be applied in relatively low amounts, to provide thin, substantially non-dripping lubricating films. In contrast to dilute aqueous lubricants, the lubricants of the invention provide drier lubrication of the conveyors and containers, a cleaner conveyor line and reduced lubricant usage, thereby reducing waste, cleanup and disposal problems. | 2014-11-27 |
20140349900 | NEW LUBRICANT FOR FORGING IN THE FORM OF A POWDER OR A COMPACTED POWDER - The present invention relates to a lubricating composition for forging in the form of a powder or a compacted powder including: one or more dicarboxylic acid(s) chosen among adipic acid, phthalic acid, isophthalic acid, terephthalic acid, sebacic acid, succinic acid and suberic acid; and one or more base(s) chosen among sodium carbonate, sodium bicarbonate, potassium carbonate and potassium bicarbonate, the dicarboxylic acid(s)/base(s) molar ratio ranging between 0.8 and 1.2. | 2014-11-27 |
20140349901 | 4(3)-(4-HYDROXY-4-METHYLPENTYL)-3-CYCLOHEXENE-1-CARBONITRILE - A compound and a fragrance composition containing the same are provided, wherein the compound has a citrus odor in addition to a muguet odor, which is useful as a fragrance, is stable in an aqueous vehicle, and can provide a bright muguet odor with good fragrance retention by being blended with another fragrance. Particularly, they are 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile and a fragrance composition containing 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile. | 2014-11-27 |
20140349902 | AQUEOUS HAIR AND SKIN CLEANING COMPOSITIONS COMPRISING BIOSURFACTANTS - The present invention is directed to compositions comprising water, at least one biosurfactant and at least one fatty acid, which are characterized in that the fraction of the sum of all surfactants in the composition is from 1 to 30% by weight, and that the fraction of fatty acid, based on the sum of fatty acid and surfactants, is from 0.1 to 20% by weight, and to the use thereof as or for producing bath additives, shower gel, shampoos, conditioners, body cleansers or skin cleansers. | 2014-11-27 |
20140349903 | DEODORIZING AND SKIN CLEANING - A method for cleaning, benefiting, or deodorizing skin or hair utilizing a body wash, skin cleaner, soap, shampoo or deodorizer formulation containing a controlled release skin benefit or deodorizing salt, a hydrophilic moisturizing polymer and surfactants is described. The method imparts benefits or deodorizing agents to the skin or hair and maintains effective levels for an extended period. | 2014-11-27 |
20140349904 | SANITARY PRODUCT IN PIECE FORM - The invention relates to the use of a sanitary product in piece form for use in the cistern of a toilet, which product comprises at least two different gel formers (1, 2) and fragrances, wherein one gel former (gel former 1) forms gels with hydrophobic liquids, which gels are insoluble or scarcely soluble in water, and the other gel former (gel former 2) is water-soluble or water-dispersible and wherein the product is transparent, gradually flushes away and releases fragrances, and gel formers 1 and 2 are in one phase. | 2014-11-27 |
20140349905 | SULFOPOLYMER-CONTAINING LIQUID CLEANING AGENT WITH LOW WATER CONTENT - A liquid cleaning agent in a water-soluble packaging containing at least one sulfopolymer and at least one polyhydric alcohol. | 2014-11-27 |
20140349906 | COLOR-PROTECTING WASHING OR CLEANING AGENT - The color preservation of detergents and cleaners during their use for the washing or cleaning of colored textiles may be improved through the use of fiber-like polyamides in a washing composition. Color transfer inhibition arises through the use of water-insoluble polyamides when these are present in the form of fibers with a small fiber diameter. This invention relates to fibers, compositions and methods relating to inhibition of color transfer in the washing or cleaning of colored textiles. | 2014-11-27 |
20140349907 | COMPACT FLUID LAUNDRY DETERGENT COMPOSITION - The present invention relates to low pH, compact fluid laundry detergent compositions comprising branched surfactants. | 2014-11-27 |
20140349908 | LOW PH DETERGENT COMPOSITION COMPRISING NONIONIC SURFACTANTS - Detergent compositions and, more specifically, low pH detergent compositions comprising nonionic surfactants that are suitable for washing of clothes, and methods of making and using the same. | 2014-11-27 |
20140349909 | WASHING OR CLEANING AGENT WITH CELLULOSE OR A CELLULOSE DERIVATIVE - The application describes a stable liquid washing or liquid cleaning agent with an acid-treated cellulose or an acid-treated cellulose derivative. The application further relates to methods of use and preparation of such stable liquid washing or liquid cleaning agents and their anti-greying powers. | 2014-11-27 |
20140349910 | Branched Alkoxylate Surfactant Composition - A composition is described containing a branched nonionic surfactant of Formula (I): (I) wherein x is a real number from 1 to 11, y is a real number from 1 to 20, R 1 is an alkyl group having 1 to 3 carbon atoms, R 2 is an alkyl group having 4 to 6 carbon atoms, and a primary 5 alcohol ethoxylate. | 2014-11-27 |
20140349911 | LOW PH MULTIPURPOSE CLEANING COMPOSITION - Cleaning compositions and, more specifically, to concentrated multipurpose cleaning compositions suitable for washing of clothes and also suitable for use on hair and skin. Methods of making and using the same. | 2014-11-27 |
20140349912 | ENZYME-CONTAINING CLEANING AGENT WITH POLYVALENT ALCOHOLS - It has been found according to the invention that enzymes may be effectively stabilized in high-viscosity cleaning agents even in the absence of conventional enzyme stabilizers by adding polyhydric alcohols | 2014-11-27 |
20140349913 | LOW PH DETERGENT COMPOSITION - Detergent compositions and more specifically, to low pH detergent compositions comprising sulfated surfactants, organic acid, and polyamine compounds. Methods of making and using the same. | 2014-11-27 |
20140349914 | CONCENTRATED SURFACTANT COMPOSITION - Concentrated surfactant compositions, and more specifically, concentrated low pH compositions comprising sulfated surfactants. Methods of making and using the same. | 2014-11-27 |
20140349915 | CLEANING COMPOSITION - An industrial cleaning composition comprises (a) from 5 to 50% by volume of an anionic surfactant having a log | 2014-11-27 |
20140349916 | LOW VOC CLEANER - A cleaner composition with improved cleaning of hydrophobic contaminants typically found on used brake assemblies and parts, including one or more low vapor pressure hydrocarbon solvents, one or more exempted volatile organic compounds, and a non-exempt volatile organic compound. | 2014-11-27 |
20140349917 | TARGETED ANTIMICROBIAL MOIETIES - This invention provides novel targeted antimicrobial compositions. In various embodiments chimeric moieties are provided comprising an antimicrobial peptide attached to a peptide targeting moiety that binds a bacterial strain or species. | 2014-11-27 |
20140349918 | DERIVATIVES OF XANTHONE COMPOUNDS - The present invention relates to xanthone analogs. Such compounds may be used in the treatment of bacterial infections. | 2014-11-27 |
20140349919 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS - The present invention relates to certain chromane-like cyclic prenylflavonoids, in particular the compounds of formulae (I), (II) and (III) as described and defined herein, for use in the treatment or prevention of a neurological disorder, as well as their use in promoting neuronal differentiation, neurite outgrowth and neuroprotection. | 2014-11-27 |
20140349920 | N-ACYLPEPTIDE DERIVATIVES AND THEIR USES - N-acylpeptide derivatives are described. Compositions comprising N-acylpeptide derivatives are therapeutically effective for topical or systemic administration to alleviate or improve conditions, disorders, diseases, symptoms or syndromes associated with tumors or cancers, immune, nervous, vascular, musculoskeletal, cutaneous system, or other tissues or systems in a subject. | 2014-11-27 |
20140349921 | HCV NS3 PROTEASE INHIBITORS - The present invention is directed to compounds, compositions and methods for treating or preventing HCV viral infections in human patients or other animal hosts. | 2014-11-27 |
20140349922 | LONG-ACTING GLP-1/GLUCAGON RECEPTOR AGONISTS - Pegylated and reverse pegylated GLP-1/Glucaron receptor agonists including pharmaceutical compositions comprising the same and methods of using the same are disclosed. | 2014-11-27 |
20140349923 | Compositions And Methods For Treating Diabetes And/Or Obesity - Compositions are disclosed which comprise one or more of the following; an anthocyanin, an oligosaccharide, a pectin, or a long-chain fatty acid. Such compositions are useful for treating diabetes or obesity. | 2014-11-27 |
20140349924 | Stable Non-Aqueous Pharmaceutical Compositions - The present invention relates to shelf stable non-aqueous pharmaceutical compositions, and to the use thereof in methods of treating diabetes and hyperglycaemia. | 2014-11-27 |
20140349925 | NOVEL INSULIN DERIVATIVES - The present invention relates to insulin derivatives which are naturally occurring insulins or analogues thereof which have a side chain attached either to the α-amino group of the N-terminal amino acid residue of the B chain or to the ε-amino group of a Lys residue present in the B chain of the parent insulin, the side chain being of the general formula: | 2014-11-27 |
20140349926 | FORMULATIONS FOR THE TREATMENT OF DIABETES - Disclosed is a formulation for parenteral administration comprising insulin that comprises a pH memory between 1 to 4 or between 6 to 8 and an aprotic polar solvent, wherein the insulin is solubilized in the aprotic polar solvent, wherein the solubilized insulin comprises stable monomeric or dimeric forms of insulin or mixtures thereof, and wherein the water content of the formulation is equal to or less than 15% w/v. | 2014-11-27 |
20140349927 | Ladostigil Therapy For Immunomodulation - Methods for treating individuals suffering from inflammation, specifically systemic inflammation including septic shock and inflammatory conditions affecting the gastrointestinal, myocardial and endocrine systems with ladostigil. | 2014-11-27 |
20140349928 | PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE - Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics. | 2014-11-27 |
20140349929 | MULTIVALENT FIBRONECTIN BASED SCAFFOLD DOMAIN PROTEINS - The present invention relates to multivalent polypeptides comprising at least two fibronectin scaffold domains connected via a polypeptide linker. The invention also relates to multivalent polypeptides for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins. | 2014-11-27 |
20140349930 | TREATMENT USING NEUBLASTIN POLYPEPTIDES - The invention relates to treatments of neuropathic pain, including tactile allodynia, and to treatments for reducing loss of pain sensitivity associated with neuropathy. The present treatments involve the use of neublastin (NBN) polypeptides. | 2014-11-27 |
20140349931 | DETECTION AND TREATMENT OF BREAST CANCER - The present invention describes methods for determining the risk that a breast precursor lesion will progress to invasive breast cancer and/or the risk of recurrent non-invasive disease in a patient, comprising detecting the presence and/or level of PAPPA and/or PAPPA functional activity in a breast tissue sample obtained from the patient, wherein if PAPPA is not present, or is present at a reduced amount compared to a control, there is the risk of progression to invasive cancer and/or the risk or recurrent disease. | 2014-11-27 |
20140349932 | ANGIOGENICALLY EFFECTIVE UNIT DOSE OF FGF-2 AND METHOD OF USE - The present invention provides a unit dose composition comprising 0.2 μg/kg to 48 μg/kg of an FGF-2 of SEQ ID NO:2, or an angiogenically active fragment or mutein thereof in a pharmaceutically acceptable carrier. Also provided is a method for treating a human patient for coronary artery disease, comprising administering into one or more coronary vessels or a peripheral vein of said patient a safe and angiogenically effective dose of a recombinant FGF-2, or an angiogenically active fragment or mutein thereof. Also provided is a pharmaceutical composition comprising a therapeutically effective amount of FGF-2, alone or in combination with heparin, in a therapeutically effective carrier. | 2014-11-27 |