47th week of 2015 patent applcation highlights part 10 |
Patent application number | Title | Published |
20150328330 | CONJUGATES OF A POLYMER, A BISPHOSPHONATE AND AN ANTI-ANGIOGENESIS AGENT AND USES THEREOF IN THE TREATMENT AND MONITORING OF BONE RELATED DISEASES - Conjugates of polymers or copolymers having attached thereto an anti-angiogenesis agent and a bisphosphonate bone targeting agent, and processes of preparing same, are disclosed. | 2015-11-19 |
20150328331 | Compositions Comprising a Polymeric Reagent and a Pharmacologically Active Agent - Pharmaceutical compositions of conjugates are provided. The conjugates can be prepared by (among other ways) conjugating a pharmacologically active agent with a polymeric reagent that has a particular arrangement of atoms. Related methods, preparations, and so forth are also provided. | 2015-11-19 |
20150328332 | ANTI-DLL3 ANTIBODY DRUG CONJUGATES - Pharmaceutical compositions to treat proliferative disorders are provided. | 2015-11-19 |
20150328333 | TOLEROGENIC SYNTHETIC NANOCARRIERS - This invention relates, at least in part, to compositions comprising synthetic nanocarriers and immunosuppressants that result in immune suppressive effects. Such compositions can further comprise antigen and provide antigen-specific tolerogenic immune responses. | 2015-11-19 |
20150328334 | MOLECULAR CONTAINERS AND METHODS OF MAKING AND USING SAME - Acyclic CB[n]-type compounds, methods of making such compounds, and uses of the compounds. For example, these compounds can be used as nanocontainers to solubilize pharmaceutical agents. Also provided are compositions and methods of using them for therapy or prophylaxis of a wide variety of conditions for which therapy or prophylaxis is desirable. | 2015-11-19 |
20150328335 | ARIPIPRAZOLE COMPLEX FORUMLATION AND METHOD - An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a β-cyclodextrin, preferably, sulfobutyl ether β-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided. | 2015-11-19 |
20150328336 | DELPHINIDIN FOR COMBATING MELANOMA CELLS - The invention relates to a composition comprising a complex of delphinidin and a sulfoalkyl ether-β-cyclodextrin for use in the treatment of malignant melanoma. | 2015-11-19 |
20150328337 | PROTECTION FROM OXIDATIVE DAMAGE BY GENE TRANSFER BY GLUTAMATE CYSTEINE LIGASE AND GLUTATHIONE SYNTHASE - An isolated polynucleotide encoding human glutamate cysteine ligase and human glutathione synthase, as well as expression constructs, vectors and pharmaceutical compositions comprising the same, are provided herein. Methods for use of these compositions in the treatment oxidative stress related diseases, including, for example, atherosclerosis, Parkinson's disease, heart failure, myocardial infarction, Alzheimer's disease, diabetes, chronic lung disease, diseases associated with mitochondrial dysfunction, diseases associated with chronic inflammation, retinitis pigmentosa, wet age related macular degeneration, dry age related macular degeneration, diabetic retinopathy, Lebers optic neuropathy, and optic neuritis are also provided. | 2015-11-19 |
20150328338 | CHEMICAL MODEL OF A NEURODEGENERATIVE DISEASE, METHOD FOR PREPARATION AND USES OF SAME - The invention concerns the use of pyridinium furosemide or one of the derivatives, analogues, salts, metabolites, or prodrugs thereof in the preparation of a chemical model of a neurodegenerative disease, preferably Parkinson's disease. The invention also concerns the corresponding chemical model and the uses of same, in particular in screening tests for identifying drug candidates. | 2015-11-19 |
20150328339 | HUMAN GLIAL CHIMERIC MODEL FOR DRUG CANDIDATE ASSESSMENT IN HUMAN GLIOTROPHIC VIRAL INFECTIONS AND PROGRESSIVE MULTIFOCAL ENCEPHALOPATHY - The present invention is directed to a method of assessing in vivo human glial cell response to pathogenic infection that involves providing a non-human mammal either with at least 30% of its glial cells in its corpus callosum being human glial cells and/or with at least 5% of its glial cells its brain and brain stem white matter being human glial cells, subjecting the non-human mammal to pathogenic infection and assessing the in vivo human glial cell response to pathogenic infection. A method of identifying therapeutic agents for the pathogenic infection as well as forms of the non-human mammal having a pathogenic brain infection are also disclosed. | 2015-11-19 |
20150328340 | METHODS AND COMPOSITIONS FOR ALTERING PHOTOPHYSICAL PROPERTIES OF FLUOROPHORES VIA PROXIMAL QUENCHING - The invention is directed to fluorophore-containing compositions and configurations wherein proximity between the fluorophore and one or more protective agents (PAs) modifies the lifetime of fluorescent and/or dark states, their frequency of occurrence, and the total lifetime of fluorescence in order to appropriately modify the photophysical characteristics of the fluorophore. The invention is also directed to methods that utilize these compositions and configurations. | 2015-11-19 |
20150328341 | RADIOPHARMACEUTICAL PRODUCTS FOR DIAGNOSIS AND THERAPY OF ADRENAL CARCINOMA - A radiopharmaceutical composition is disclosed comprising novel iodometomidate derivatives of formula (I) which bind specifically to adrenal enzymes and which exhibit an improved stability. The compounds of formula (I) are suitable for use in a diagnostic imaging method, e.g. for diagnosis of adrenocortical carcinoma. The compounds of formula (I) are further suitable for use in the treatment of adrenocortical carcinoma, by means of radionuclide therapy. | 2015-11-19 |
20150328342 | NOVEL TRICARBOCYANINE-CYCLODEXTRIN(S) CONJUGATES AND USE THEREOF - The present invention relates to novel tricarbocyanine-cyclodextrin(s) conjugates useful as markers in the diagnosis of kidney diseases, a diagnostic composition comprising said conjugates, their use and their production. | 2015-11-19 |
20150328343 | CONTRAST MEDIUM, METHOD AND KIT FOR PREPARING SAME - Provided is a contrast medium comprising at least one molecular probe and at least one optical probe on a surface of a substrate having an ultrasound imaging function. More specifically, a contrast medium having sensitivity to not only ultrasound but also light excellent in real-time imaging and resolution and having a size sufficient to travel into tissues through blood vessel can be provided by labelling an ultrasound imageable substrate with a molecular probe and an optical probe. | 2015-11-19 |
20150328344 | Fluorination Process - The invention relates to a process for preparation of a compound of formula (I): | 2015-11-19 |
20150328345 | NOVEL LABELING COMPOSITION FOR CANCER LESION - The present invention relates to a labeling composition for a cancer lesion, having a complex in which a pigment for straining living tissues, a radioactive isotope, or a combination thereof binds to macro aggregated albumin (MAA). A method for providing information regarding a cancer lesion site using the labeling composition for a cancer lesion. A labeling kit for a cancer lesion having the labeling composition for a cancer lesion; and a complex in which a pigment for straining living tissues binds to MAA included in the labeling composition for a cancer lesion. The labeling composition for a cancer lesion according to the present invention binds to a cancer lesion to detect a site, size, and the like of the cancer lesion in real time, thereby improving the success rate of a surgical operation for the cancer lesion and also preventing excessive loss of normal tissues. | 2015-11-19 |
20150328346 | MULTIMODAL PARTICLES, METHODS AND USES THEREOF - The present disclosure, among other things, provides a composition of a particle including a substrate; at least a first condensation layer comprising at least a first dopant entity; and at least a second layer comprising a second dopant entity. In some embodiments, different dopant entities are included in different layers. In some embodiments, such dopant entities are or comprise detectable entities. This, in some embodiments, provided technologies achieve multi-modality particles. Among the many advantages of provided technologies include the ability to image particles by a plurality of distinct imaging modalities and/or in a plurality of contexts (e.g., pre-surgical, intraoperative and/or post-surgical environments). The present invention provides methods that include a single administration of particles to a subject, followed by a plurality of steps that comprise imaging the administered particles, which steps may utilize different imaging technologies and/or be performed at different times and/or in different environments. | 2015-11-19 |
20150328347 | FIBROUS MATERIALS AND COMPOSITES - Fibrous materials, compositions that include fibrous materials, and uses of the fibrous materials and compositions are disclosed. For example, the fibrous materials can be operated on by a microorganism to produce ethanol or a by-product, such as a protein or lignin. | 2015-11-19 |
20150328348 | DRYING AND DISINFECTING SYSTEM, METHOD AND DEVICE FOR BABY BOTTLES AND OTHER ITEMS USING INFRARED LIGHT AND ULTRAVIOLET RADIATION - A drying and disinfecting device utilizing ultraviolet radiation (UV) and infrared light (IR) to dry and disinfect baby bottles and other objects placed therein, the device comprising: a drying and disinfecting chamber for containing small objects to be dried and disinfected therein; an ultraviolet light source and an infrared light source operable to expose baby bottles and other objects to ultraviolet radiation; a protective UV-blocking viewing window; a convenience handle for portability; a user interface; a controller, the controller operable to: initiate a drying and disinfecting cycle in which the ultraviolet light source is caused to emit ultraviolet light in response to user input via the user interface; and cause the user interface to indicate a status of the device. The device creates significant convenience over and avoids the disadvantages of the traditional use of high heat, moisture and steam to dry and disinfect baby bottles and other objects. | 2015-11-19 |
20150328349 | SANITIZER WITH AN ION GENERATOR - An ion generator configured to generate ions for use in hand dryers and sanitizers for sanitizing various surfaces including hands, hardware, fixtures, appliances, countertops, equipment, utensils and specifically to a chemical-free ion generators that do not use sacrificial anodes and cathodes, more specifically to an ozone-free ion generators and yet more specifically to an electronic ion generator using AC and a single ion source electrode with a ground plane electrode. | 2015-11-19 |
20150328350 | Apparatus and Method for Sanitizing - An apparatus and system that efficiently and effectively delivers a sanitizing fluid to ducts in the form of a fog or mist is described. A canister that contains a liquid sanitizing solution is attached to a compressor and includes a straw that has an internal passageway that extends into the liquid and a venturi tube above the level of the liquid that connects with the internal passageway in the straw. The headspace above the liquid in the canister is pressurized, causing fluid to flow upwardly in the straw when a trigger is depressed, drawing fluid upwardly in part by the venturi. As the liquid passes the venturi the pressurized air that is flowing into the venturi causes the fluid to form a fine mist. The mist, under pressure from the compressor, is routed into a flexible delivery tube that has been previously positioned in a duct system. The terminal end of the tube has an atomizing ball attached thereto and the atomizing ball has a series of orifices through which the misted, atomized fluid is delivered. As fogged sanitizing solution flows through the orifices it is deposited on the interior surfaces of the duct. The delivery tube and the attached atomizing ball are withdrawn from the duct as the sanitizing fog is emitted from the ball. The fan in the HVAC system is not activated so there is no deliver of the sanitizer through registers and into the living space. The apparatus and method may be used to apply other fluids to other surfaces. | 2015-11-19 |
20150328351 | SYSTEMS AND METHODS FOR DETERMINING THE CLEANLINESS OF A SURFACE - Systems and methods for determining the cleanliness of a surface. Surface marking systems of the present disclosure can include a plurality of retroreflective microspheres dispersed in or dispensed on a carrier. Applicators of the present disclosure can include a container comprising the surface marking system, and a dispenser. Methods of the present disclosure can include applying the surface marking system to at least one discrete site on the surface; illuminating the at least one discrete site on the surface with visible light, after a cleaning; and detecting retroreflection emitted from the at least one discrete site on the surface in response to illuminating the at least one discrete site to determine the effectiveness of the cleaning of the surface. | 2015-11-19 |
20150328352 | CHEMICAL INDICATING COMPOSITION, AUTOCLAVE TAPE AND METHOD FOR PREPARING AUTOCLAVE TAPE - The invention relates to a chemical indicating composition, an autoclave tape utilizing the chemical indicating composition, and a method of preparing the autoclave tape. The chemical indicating composition of the invention comprises an indicator, an organic silicone modified polymer and a solvent; wherein, the indicator comprises a bismuth compound, a sulfur source, and a compound capable of generating alkaline conditions when exposed to steam at a high temperature. The chemical indicating composition can be coated directly onto the non-adhesive surface of the adhesive tape, so as to accomplish the preparation of the autoclave tape in one step. | 2015-11-19 |
20150328353 | Candle Warming Image Display Lamp - The present invention is a candle warming image display lamp (CWIDL) for use in displaying user selectable images while providing light such as to light a room brightly or as a night light, while also warming a preferably spill resistant wickless scented candle, without spilling hot molten candle wax. | 2015-11-19 |
20150328354 | Scent Machine with Filter - A scent machine includes a housing defining an interior chamber with a top cone in which is defined a top opening and a slot defined circumferentially in a wall of the top cone. The machine further includes a filter housed and a fan housed within the chamber. The slot receives a fragrance-infused disc. | 2015-11-19 |
20150328355 | Air Purifying Apparatus, Method and System - An air-purifying apparatus draws in an airflow from an ambient environment, kills germs in the airflow within the apparatus and expels the airflow purified back into the environment. The apparatus has a housing with an interior chamber. An airflow enters the chamber through an inlet. From the interior chamber, the airflow is expelled through an outlet. The apparatus has an airflow-germ-killing-system that kills germs in the airflow. The apparatus has an airflow-generator which causes the airflow to flow from the inlet to the outlet. In an aspect of the invention, the apparatus has a three-dimensional filter structure that has air-filter-surfaces that define a filter interior region and encompassed by the air-filter-surfaces of the filter structure. The filter is positioned in connection with the inlet so that airflow entering the inlet is dispersed into the housing interior chamber in multiple directions exclusively through the air-filter-surfaces of the three-dimensional filter structure. | 2015-11-19 |
20150328356 | SPOUTING OR SPITTING CETACEAN AUTOMATIC AIR FRESHENER - The purpose or the art is to freshen the air in living spaces via an automatic air freshener designed to appear like a spouting or spitting cetacean. The invention consists of a manufactured cetacean which may or may not house the inner working parts; an optional spherical mid-section which houses the working parts consisting of a bracket that holds an aerosol spray can, a motor, gears, a motor controller, batteries, and a tube. The motor drives a set of gears which engage a fan shaped lever type gear connected to an actuating bolt that depresses the nozzle of the aerosol spray can. These parts are housed in the manufactured cetacean's body or the art's mid-section. The invention will be supported by a base. The working parts provide the mechanisms by which the spouting a spitting cetacean expels air freshener through its blow hole or mouth via a tube connected to either orifice. | 2015-11-19 |
20150328357 | WOUND PROTECTING POLYMERS - A wound protecting composition includes an end-functionalized arborescent polymer having at least two branching points to provide at least four ends to the arborescent polymer, the arborescent polymer comprising polyisobutylene; and an end group attached to a majority of the ends of the arboresent polymer, the end group comprising an alkyl cyanoacrylate. The composition may further include a blend of the end-functionalized arborescent polymer with an independent alkyl cyanoacrylate. | 2015-11-19 |
20150328358 | AGGLOMERATED SUPERABSORBENT POLYMER PARTICLES - The present invention relates to agglomerated superabsorbent polymer particles which have been agglomerated by using a multivalent salt having a valence of three or higher. Due to agglomeration, the mean average particle size increase by at least 25% compared to the mean average particle size of the non-agglomerates superabsorbent polymer particles. | 2015-11-19 |
20150328359 | ABSORBENT ARTICLE - An absorbent article includes a liquid-permeable top sheet configured to be arranged on a skin side, a liquid-impermeable back sheet configured to be arranged on a clothing side; a liquid-retaining absorbent body arranged between the top sheet and the back sheet; a first sheet arranged between the top sheet and the absorbent body and within the area in which the absorbent body is arranged; and a second sheet arranged between the first sheet and the absorbent body. The first sheet is liquid permeable and has liquid-retaining properties. The second sheet is liquid permeable but does not have liquid-retaining properties and hides the red color of menstrual blood absorbed by the absorbent body. | 2015-11-19 |
20150328360 | CHLORHEXIDINE GLUCONATE COMPOSITIONS, RESIN SYSTEMS AND ARTICLES - Compositions containing chlorhexidine gluconate solubilized in hydrophobic vehicles are described. Resin systems containing such chlorhexidine gluconate compositions, including adhesives and articles incorporating such resin systems, including medical articles such as drapes are also described. | 2015-11-19 |
20150328361 | ERODIBLE EMBOLIZATION MATERIAL - An embolization agent for use with a therapeutic drug solution for treating diffuse diseases in a targeted tissue vessel of a patient and a process thereof is presented. This embolization agent comprises an inner core of a fast dispersing material having a diameter less than a predetermined size for the opening in the targeted tissue vessel; and an outer sphere of an embolization material encompassing the inner core and having an initial diameter to occlude the initial opening in the targeted tissue vessel. During the treatment of the disease, the outer sphere of embolization material erodes at a predetermined rate, enhancing penetration of the embolization agent into the opening in the targeted tissue vessel. The inner core disperses into the targeted tissue vessel after becoming exposed by the erosion of the embolization material of the outer sphere. | 2015-11-19 |
20150328362 | THROMBIN-FREE BIOLOGICAL ADHESIVE AND USE THEREOF AS A MEDICAMENT - The invention relates to a thrombin-free, fibrinogen-based biological adhesive for therapeutic use, which comprises factor VIIa and a source of calcium ions. The invention also relates to the use of the biological adhesive as a medicament, in particular as a dressing for biological tissues, wounds or biomaterials. | 2015-11-19 |
20150328363 | USE OF SELF-ASSEMBLING POLYPEPTIDES AS TISSUE ADHESIVES - The present invention relates to a self-assembling polypeptide for use as tissue adhesive. The present invention also relates to the use of a self-assembling polypeptide as tissue adhesive. Further, the invention is directed to the use of a self-assembling polypeptide to glue one or more cosmetic compounds on skin, mucosa, and/or hair. Furthermore, the invention is directed to a self-assembling polypeptide for use in gluing one or more pharmaceutical compounds on tissue, skin, mucosa, and/or hair. | 2015-11-19 |
20150328364 | A COMPOSITION FOR MAKING A CEMENT OR AN IMPLANT - A composition for making a cement or an implant, the composition comprising a silicate glass and at least one compound selected from the group consisting of a calcium phosphate salt, a strontium phosphate salt and a phosphate glass. | 2015-11-19 |
20150328365 | POROUS POLYSACCHARIDE SCAFFOLD COMPRISING NANO-HYDROXYAPATITE AND USE FOR BONE FORMATION - The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralisation of a tissue in osseous site, as well as in non-osseous site, in the absence of stent cells or growth factors. | 2015-11-19 |
20150328366 | Process For Demineralization of Bone Matrix With Preservation of Natural Growth Factors - A demineralized bone matrix is produced by a process in which a bone body is placed in a first processing solution comprising an acid to demineralize the bone body. The bone body is periodically removed from the first solution at specific time intervals to perform at least one test, such as a compression test, on a mechanical property of the bone body. When the test yields a desired result, the bone body is exposed to a second processing solution that is less acidic than the first, thus minimizing the exposure of the bone body to the harsh acidic conditions of the demineralization phase of the process. | 2015-11-19 |
20150328367 | Cellular Seeding and Co-Culture of a Three Dimensional Fibroblast Construct - The present invention provides methods for cellular seeding onto three-dimensional fibroblast constructs, three-dimensional fibroblast constructs seeded with muscle cells, and uses therefore. | 2015-11-19 |
20150328368 | Cement-Forming Compositions, Monetite Cements, Implants and Methods for Correcting Bone Defects - A calcium phosphate monetite cement-forming composition comprises a monetite-forming calcium-based precursor powder and from 3 to 30 wt %, based on the weight of the precursor powder, of dicalcium pyrophosphate powder. Monetite cements formed form such compositions may be used in implants for correcting bone defects. Methods for bone defect repair employ implants formed from such monetite cements and slow implant resorption and/or improve in vivo bone induction in a patient. | 2015-11-19 |
20150328369 | METHOD OF TREATING PERIPHERAL ARTERY DISEASES IN LOWER LIMBS - A method of treating peripheral artery diseases in lower limbs by providing a medical device having an expandable member having a drug coating layer which has a crystalline morphological form including a plurality of crystal particles of a water-insoluble drug regularly arranged and uniformly sized on the surface of the medical device, inserting the medical device in peripheral blood vessels, expanding the expandable member, pressing the drug coating layer to a blood vessel wall such that at least part of the plurality of crystals are transferred to the blood vessel wall, and deflating the expandable member such that a pharmacokinetics profile is presented in which a drug concentration in the blood vessels is kept for the inhibition of smooth muscle cell proliferation in a high drug-concentration period of time, and for the non-inhibition of endothelial cell growth in a later low drug-concentration period of time. | 2015-11-19 |
20150328370 | Device and Method for Inhibiting Movement of a Medical Device in a Patient - A medical device such as a cannula, catheter, needle or biosensing probe includes an elongated body for penetrating, inserting and/or positioning in or through the skin of a patient. The elongated body has an outer surface that when positioned in the patient with a coefficient of friction sufficient to inhibit movement between the elongated body on the skin at the insertion site to inhibit irritation at the infusion site. A lubricious coating is provided on the elongated body to assist in penetration and/or insertion of the elongated body into the patient. The lubricious coating can be removed by a shearing action by the insertion of the elongated body into the patient and/or by absorption of the lubricious coating to expose the outer surface of the elongated member. | 2015-11-19 |
20150328371 | METHOD OF REDUCING THE RISK OF EMBOLIZATION OF PERIPHERAL BLOOD VESSELS - A method of reducing the risk of embolization of peripheral blood vessels by providing a medical device having an expandable member having a drug coating layer which has a crystalline morphological form including a plurality of crystal particles of a water-insoluble drug regularly arranged and uniformly sized on the surface of the medical device, inserting the medical device in peripheral blood vessels, expanding the expandable member, pressing the drug coating layer to a blood vessel wall such that at least part of the plurality of crystal particles are transferred to the blood vessel wall, and deflating the expandable member such that the generation of microparticulates having a size that causes embolization of peripheral blood vessels is suppressed. | 2015-11-19 |
20150328372 | METHOD OF INHIBITING THICKENING OF VASCULAR INTIMA - A method of inhibiting thickening of vascular intima by providing a medical device having an expandable member having a drug coating layer which has a crystalline morphological form including a plurality of crystal particles of a water-insoluble drug regularly arranged and uniformly sized on the surface of the medical device, inserting the medical device in peripheral blood vessels, expanding the expandable member, pressing the drug coating layer to a blood vessel wall such that at least part of the plurality of crystals are transferred to the blood vessel wall, and deflating the expandable member such that a vascular intima thickening is inhibited uniformly in an entire treated lesion of stenosis to uniformly cause patency of the lesion. | 2015-11-19 |
20150328373 | Additives To Increase Degradation Rate Of A Biodegradable Scaffolding And Methods Of Forming Same - Methods of making biodegradable polymeric devices, such as stents, with one or more modifications to alter the degradation rate, and the biodegradable polymeric devices are described. Modifications include blending of two polymers, one with a different degradation rate, inclusion of additives to alter the degradation rate, and the use of polymers of a high polydispersity. | 2015-11-19 |
20150328374 | COATING COMPRISING POLYESTERAMIDE COPOLYMERS FOR DRUG DELIVERY - The invention relates to a coating comprising a biodegradable polymer comprising at least two different functional groups pendant to the polymer backbone, which functional groups are selected from the group of carboxyl-, amine, hydroxyl, ester, amide-, thiol- or thioester groups. The two different functional groups comprise at least an unprotected hydrophilic functional group chosen from a carboxyl-, amine, thiol or hydroxyl group and at least a protected hydrophobic functional group chosen from an ester, amide- or thioester group. The invention further relates to an implantable device comprising the coating composition. The implantable device is includes cardiac pacemakers and defibrillators; leads and electrodes for the preceding, organ stimulators such as nerve, bladder, sphincter and diaphragm stimulators, prostheses, rods, vascular grafts, self-expandable stents, balloon-expandable stents, stent-grafts, grafts, catheters, artificial heart valves and cerebrospinal fluid shunts. | 2015-11-19 |
20150328375 | Phosphoryl Choline Coating Compositions - A polymer comprising phospholipid moieties and a biocompatible polymer backbone, a composition comprising the polymer and optionally a bioactive agent, an implantable devices such as a DES comprising thereon a coating comprising the polymer and optionally a bioactive agent, and a method of using the device for the treatment of a disorder in a human being are provided. | 2015-11-19 |
20150328376 | IMPLANTS FOR THE TREATMENT OF DOPAMINE ASSOCIATED STATES - Biodegradable implants comprising dopamine modulating compounds are described. | 2015-11-19 |
20150328377 | COMPOSITION OF D-ALPHA HYDROXY ACIDS AND ANTIMICROBIALS - The present invention relates to an antimicrobial composition, which is a synergistic combination comprising an anti-microbial agent and a polymer or monomer comprising D-alpha hydroxy acid or a polymer capable of releasing a D-alpha hydroxy acid monomer. The present invention also relates to methods for using and applying the same. | 2015-11-19 |
20150328378 | ANTIBACTERIAL COATINGS THAT INHIBIT BIOFILM FORMATION ON IMPLANTS - Orthopedic and dental implants coated with an antibacterial coating and methods of making and using, are described herein. The implant can be coated with a hydrophobic, polycationic antibacterial polymer. The polymer can be covalently or non-covalently associated with the surface; however, in particular embodiments, the polymer is non-covalently associated with the surface. As shown in the examples below, clinical observations, digital radiography, and a battery of well-accepted ex vivo analytical methods show that the presence of a hydrophobic polycationic polymer coating, such as N,N-dodecyl,methyl-PEI coating on the surface of a metal implant, was effective in eliminating the clinical signs of infection in vivo in a large animal infection model. Moreover, the coated plates supported bone healing, and in fact decreased healing times, even in the presence of significant bacterial contamination compared to a control. | 2015-11-19 |
20150328379 | FLUID MANAGEMENT SYSTEM WITH PASS-THROUGH FLUID VOLUME MEASUREMENT - A fluid management system including a pass-through fluid volume measurement system to provide continuous measurement of fluid returned from a surgical site during transit to a waste collection system. The pass-through fluid volume measurement system eliminates the need to physically replace full fluid collection containers during the medical procedure with new, empty fluid collection containers. | 2015-11-19 |
20150328380 | BREAST SHIELD UNIT WITH MEDIA SEPARATION - A breastshield unit for use with a breastpump for expressing human breastmilk has a breastshield for receiving a mother's breast and a media separation device for transferring a vacuum into the interior of the breastshield. The breastshield has a receiving area for receiving a nipple of the mother's breast. The media separation device has a media separation membrane which, for the purpose of transferring the vacuum, is movable to and fro between two positions. The media separation membrane is located in the receiving area at least in one of the two positions. Despite the integrated media separation, the breastshield unit can be made extremely compact and minimizes the dead volume. | 2015-11-19 |
20150328381 | TISSUE ROLL SCAFFOLDS - An apparatus and system for treating a wound having a cavity is disclosed. The apparatus comprises a scaffold including a scaffold lamina and a tissue lamina wherein the scaffold lamina forms a laminate in fluid communication with the tissue lamina. The laminate is rolled into a generally cylindrical shape having two end surfaces. The apparatus further comprises a manifold having a port for coupling to a source of reduced pressure and that is positioned in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. The apparatus also comprises a drape formed of substantially impermeable material to cover the scaffold and the manifold within the wound. A method for treating a wound having a cavity is also disclosed and comprises positioning a scaffold lamina adjacent a tissue lamina to form a laminate in fluid communication with the tissue lamina, rolling the laminate into a generally cylindrical shape having two end surface, and positioning the scaffold within the cavity of the wound to provide reduced pressure to the wound. The method further comprises positioning a manifold in fluid communication with the scaffold to provide reduced pressure to the scaffold lamina and the wound. | 2015-11-19 |
20150328382 | CANNULA ASSEMBLY - Cannula assemblies and methods of manufacturing cannula assemblies are provided. The cannula assembly includes a cannula and a pigtail extension coupled to the cannula. The pigtail extension includes a proximal section having a first stiffness and a distal section having a second stiffness, the first stiffness greater than the second stiffness. The proximal section of the pigtail extension is positioned between the cannula and at least a portion of the distal section. | 2015-11-19 |
20150328383 | BLOOD PUMP HOUSING COMPONENT - Blood pump assemblies and methods of manufacturing and operating blood pump assemblies are provided. The blood pump assembly includes a pump and an impeller blade rotatably coupled to the pump. The blood pump assembly also includes a pump housing component sized for passage through a body lumen and coupled to the pump. The pump housing component includes a peripheral wall extending about a rotation axis of the impeller blade. The peripheral wall includes an inner peripheral wall surface and an outer peripheral wall surface. The peripheral wall also includes one or more blood exhaust apertures. Each blood exhaust aperture in the one or more blood exhaust apertures is defined by an inner aperture edge and an outer aperture edge. Each inner aperture edge is chamfered between the inner peripheral wall surface and the outer peripheral wall surface. | 2015-11-19 |
20150328384 | ARTIFICIAL HEART CONTROL DEVICE, ARTIFICIAL HEART SYSTEM AND ARTIFICIAL HEART CONTROL METHOD - Provided is an artificial heart control device for controlling a blood pump which assists flow of blood in a heart, the artificial heart control device including: a timing detection part which is configured to detect reference timing within a cardiac cycle of the heart; and a blood pump control part which is configured to control a rotational speed of the blood pump, wherein the blood pump control part controls, with reference to the reference timing detected by the timing detection part, the rotational speed of the blood pump such that the rotational speed becomes a rotational speed corresponding to a predetermined control pattern. According to the present invention, it is possible to provide an artificial heart control device, an artificial heart system and an artificial heart control method which can provide a load control optimum for the recovery of functions of a patient's own heart. | 2015-11-19 |
20150328385 | COMBINATION OF A SINGLE-STATION REVERSE OSMOSIS DEVICE WITH A HEMODIALYSIS DEVICE - A combination of a single-station reverse-osmosis (RO) device comprising a hemodialysis device (HD device) is characterized in that a connection line is provided with a buffer chamber for permeate which serves on the one hand a faster permeate supply into the HD device and on the other hand a generation of a negative transmembrane pressure, and that upon request by the HD device the permeate flows either via the water inlet valve into the HD device or via a flushing valve of the HD device to an outlet. | 2015-11-19 |
20150328386 | FLUID PURIFICATION SYSTEM - Certain disclosed embodiments concern systems and methods of preparing dialysate for use in a home dialysis system that is compact and light-weight relative to existing systems and consumes relatively low amounts of energy. The method includes coupling a household water stream to a dialysis system; filtering the water stream; heating the water stream to at least about 138 degrees Celsius in a non-batch process to produce a heated water stream; maintaining the heated water stream at or above at least about 138 degrees Celsius for at least about two seconds; cooling the heated water stream to produce a cooled water stream; ultrafiltering the cooled water stream; and mixing dialysate components into the cooled water stream in a non-batch process. | 2015-11-19 |
20150328387 | EXTRACORPOREAL PERFUSION APPARATUS - Embodiments of the invention relate to an extracorporeal perfusion apparatus comprising an extracorporeal blood circuit for conveying blood, a filtrate circuit for conveying blood plasma, and a controller, wherein the filtrate circuit is connected to the extracorporeal blood circuit by means of a filter, wherein the filter has a sieving coefficient of 5% for substances having a molar mass of 340,000 g/mol (relative molecular mass of 340 kDa), and wherein a depletion agent comprising a first carrier having a neutral, hydrophobic surface is arranged in the filtrate circuit, wherein the perfusion apparatus comprises a dispensing means for feeding an endotoxin-binding lipopeptide into the extracorporeal blood circuit, wherein the endotoxin-binding lipopeptide is selected from the group consisting of polymyxins, polymyxin derivatives, prodrugs thereof, and a combination thereof. | 2015-11-19 |
20150328388 | DEVICE FOR SEPARATING/HOUSING BLOOD COMPONENTS AND METHOD FOR PREPARING PLATELET-RICH PLASMA - Provided are: a device that is for separating/housing blood components and that can more easily and aseptically separate/house platelet-rich plasma; and a method for preparing platelet-rich plasma. The device for separating/housing blood components is provided with: a blood storage section; a component housing section for housing a component that is part of blood; and a linking tube that joins the blood storage section and the component housing section. The blood storage section has: a tube-shaped blood storage vessel; a blood lead-in pathway; and a component lead-out pathway. The component housing section has a component lead-in pathway and a metal needle. | 2015-11-19 |
20150328389 | Device for Detecting Moisture for Use With A Device for Monitoring An Access to A Patient, In Particular For Monitoring the Vascular Access In An Extracorporeal Blood Treatment - A device for detecting moisture for use with a device for monitoring an access to a patient for an extracorporeal blood treatment apparatus is described. The device for detecting moisture is constituted as a two-dimensionally extending fabric to be placed on the patient's skin, having an electrically conductive structure as a moisture sensor and constituted by non-conductive and conductive warp and weft threads configured to produce in the woven fabric a defined electrically conductive structure through spatial separation of the warp and weft threads. By the use of conductive warp and weft threads, an electrically conductive structure can be constituted having sections running in different directions, thereby creating a moisture sensor exhibiting a particularly high degree of sensitivity. The electrically conductive structure is preferably terminated with a terminating resistor, preferably not a component part but rather part of a connection part of the device, so that production is simplified. | 2015-11-19 |
20150328390 | Pumping System and Method for Assisting a Patient's Heart - A cannula for a patient includes an elongate body having a length of at least 70 cm and a channel extending through the body defining a wall. The cannula includes a wire embodied within at least a portion of the wall. The body has a proximal end, a distal end having a tip opening through which the channel extends and a plurality of side holes through the wall in proximity to the tip for unimpeded flow of blood at the distal end. The cannula includes a barbed fitting at the proximal end. The cannula includes a suture wing for securing the elongated body to the patient. A system for assisting a patient's heart. A method for assisting a patient's heart. | 2015-11-19 |
20150328391 | CELL REMOVAL METHOD, CELL REMOVAL SYSTEM, AND WHITE BLOOD CELL REMOVAL METHOD - In the removal of white blood cells from blood, the efficiency of white blood cell removal by a filter is improved. Centrifugal force is applied to blood placed in a blood bag by centrifugal separation to form a plurality of separation layers having a concentration gradient of white blood cells. The separation layers are passed through a filter in ascending order of white blood cell concentration to remove the white blood cells from the separation layers. The separation layers from which the white blood cells have been removed are received in a first blood component bag. | 2015-11-19 |
20150328392 | CELL REMOVAL METHOD, CELL REMOVAL SYSTEM, AND WHITE BLOOD CELL REMOVAL METHOD - In the removal of white blood cells from blood, the efficiency of white blood cell removal by a filter is improved. Centrifugal force is applied to blood placed in a blood bag by centrifugal separation to form a plurality of separation layers having a concentration gradient of white blood cells. The separation layers are passed through a filter in ascending order of white blood cell concentration to remove the white blood cells from the separation layers. The separation layers from which the white blood cells have been removed are received in a first blood component bag. | 2015-11-19 |
20150328393 | Limb Irrigation Pan Device - A limb irrigation pan device collects and removes irrigation fluid and debris from a surgical field when a limb is irrigated. The device includes a frame having a pair of opposed ends and a pair of longitudinal sides extending between the opposed ends. Respective upper surfaces of each opposed end are concavely arcuate and an upper edge of the frame defines an open top of the frame. A base is coupled to the opposed ends and the longitudinal sides defining a well for collecting a fluid passed into the frame through the open top. A porous sling is coupled to the frame for passing the fluid through the sling to be collected in the well. A drain coupled to the frame is in fluid communication with the well wherein the drain drains the fluid from the well. | 2015-11-19 |
20150328394 | Devices and Methods for Transnasal Dilation and Irrigation of the Sinuses - A medical device, and a system and packaged kit containing the medical device for the treatment of a sinus opening is described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and an irrigation lumen the proximal and. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to said distal end. The irrigation tip is distal to the balloon on the distal shaft section and has a tip opening and one or more radially facing openings. A method for treating a sinus opening includes inserting a system that includes the medical device, a sinus guide catheter and a sinus guide element into a patient's anatomy, dilating the sinus opening and irrigating a target in the nasal anatomy. | 2015-11-19 |
20150328395 | CLEANING A PLURALITY OF NEEDLES, POST MANUFACTURE AND BEFORE ASSEMBLY INTO A SYRINGE, CANNULA AND THE LIKE - A system for cleaning a plurality of needles includes a conveyor for conveying a plurality of jigs through a series of stations, and each jig is arranged to contain at least some of the needles. The stations include a pre-treatment station for the removal of detritus from the needles, an electronic polishing station, a post-treatment station for removal of material from the surface of the treated needles, a cleaning station for cleaning the needles, a drying station, and an unloading station for unloading the needles from the jigs. | 2015-11-19 |
20150328396 | MEDICATION SAFETY DEVICES AND METHODS - A medication safety device and method can include an infusion pump and a drug library in communication with the infusion pump. The drug library can have upper hard and soft limits and lower hard and soft limits associated with at least one drug. A graphical user interface can display a bar chart showing upper and lower soft limit bars for the at least one drug. The upper and lower soft limit bars can be grabbed and dragged on the graphical user interface in touch-screen fashion to new positions associated with new upper and lower soft limits. The graphical user interface and associated hardware and software can be configurable to responsively re-analyze data and compare a particular infusion to the new upper and lower soft limits. | 2015-11-19 |
20150328397 | DOUBLE ARM POST SUPPORT ASSEMBLY - A support arm assembly includes a support arm, the support arm including a support arm connector hub and a support arm body; and a split arm, the split arm including a split arm connector hub and a support hub, the split arm connector hub connecting to the support arm connector hub. | 2015-11-19 |
20150328398 | IV Holder - An IV holder includes a base for supporting the IV holder on a floor. A first end of a post extends from the base and a distal second end area of the post has an IV bag hook. The IV bag hook is positioned substantially over a center of gravity of the IV holder when the base is positioned on the floor. The post has an offset area so that the post doesn't interfere with an IV bag suspended from the IV bag hook. | 2015-11-19 |
20150328399 | PUMP FOR MEDICAL PURPOSES - A medical fluid pump, comprising a first, inner fluid system including a motor-driven suction/pressure unit and a first fluid pressure chamber which can be filled with fluid and emptied by the suction/pressure unit, and a second, outer fluid system including a second fluid pressure chamber which is coupled to the first pressure chamber in a pressure- and/or volume-dynamic manner via a movable separating wall and which is alternately coupled—via a valve means of the second fluid system—to a suction line and pressure line depending on the current working phase of the suction/pressure unit of the first fluid system is disclosed. | 2015-11-19 |
20150328400 | HYDRAULICALLY ACTUATED PUMP FOR FLUID ADMINISTRATION - A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. | 2015-11-19 |
20150328401 | PIVOTING JOINT INFUSION SYSTEM WITH SEAL - An infusion system for delivery of therapeutic fluids from a remote source into a patient's body. The system has an infusion assembly, a rotating pivot joint member, a fluid connector assembly, and a sealing assembly retained within the infusion assembly between the housing of the infusion assembly and the rotating pivot joint member. The seal reduces leakage of fluids. The rotating joint may be pivoted to three distinct positions to allow for emplacement on the patient, delivery of the therapeutic fluid to the patient, and protected, sealed closure of the fluid channels to avoid patient fluid backflow. | 2015-11-19 |
20150328402 | ADAPTIVE SIGNAL PROCESSING FOR INFUSION DEVICES AND RELATED METHODS AND SYSTEMS - Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device involves obtaining a filtered measurement indicative of a physiological condition of a user, determining a metric indicative of a characteristic of the filtered measurement based at least in part on one or more derivative metrics associated with the filtered measurement, and determining an output measurement indicative of the physiological condition of the user based at least in part on the filtered measurement, the metric, and a previous output measurement. | 2015-11-19 |
20150328403 | GLUCOSE CONSUMPTION MONITOR - Apparatus and methods for monitoring and indexing glucose consumption are disclosed. Embodiments of the present invention provide for accurate measurement of small differences in blood glucose values at various points in the body. These accurate measurements can be used to monitor glucose uptake in specific organs of the body such as the brain or heart. The apparatus includes an upstream intravascular glucose sensor and a downstream intravascular glucose sensor. In some embodiments, substantially simultaneous fluid communication of a calibration fluid to both glucose sensors reduces bias between the sensors. A processor is used to calculate and optionally display blood glucose consumption. Oxygen consumption can also be determined and used to determine and display an index value that is indicative of any mismatch between the two. In some embodiments, insulin and/or glucose infusion can be controlled by the system. | 2015-11-19 |
20150328404 | PHARMACEUTICAL INJECTION DEVICE - The pharmaceutical injection device of the present invention comprises a cartridge holder, a main case, a piston, a motor, an opening component, an open/closed detection switch, and a controller. The motor drives the piston in either an insertion direction in which the piston is inserted into a pharmaceutical cartridge, or a pull-out direction in which the piston is pulled out of the pharmaceutical cartridge. The opening component opens the cartridge holder in conjunction with the movement of the piston in the pull-out direction. The open/closed detection switch detects whether the cartridge holder is open or closed. When the open/closed detection switch detects that the cartridge holder is open, the controller controls the motor so as to stop the piston. | 2015-11-19 |
20150328405 | HIGH FORCE INJECTION DEVICES - Described herein are assisted syringes. The syringes provide a higher force to the plunger tip than the extrusion force applied to the plunger. The assisted syringes can be used to inject or extrude viscous materials. | 2015-11-19 |
20150328406 | HAND-HELD PRE-FILLED SYRINGE ASSEMBLY - A hand-held pre-filled syringe assembly comprises a syringe barrel, a piston slidably located within the syringe barrel, biasing means coupled to the piston and acting to bias the piston within the syringe barrel, a hypodermic needle, and an openable closure having an inlet and an outlet disposed between the syringe barrel and the hypodermic needle. The inlet of the openable closure is removably coupled to a nozzle of the syringe barrel by a first coupling and the outlet of the openable closure is coupled to a proximal end of the hypodermic needle by a second coupling. The openable closure defines a through-channel extending between the inlet and the outlet that is closed by a normally-closed valve. The syringe assembly contains a liquid medicament retained within the syringe barrel under pressure applied by the piston such that the liquid medicament is delivered through the hypodermic needle when the normally-closed valve is opened. | 2015-11-19 |
20150328407 | Syringe barrel - A syringe barrel including a tubular, barrel body operable to receive a syringe plunger at a proximal end thereof and a syringe needle at a distal end and sidewalls of said syringe body being flexible and elliptical in cross-section and opposing compression of said syringe barrel at opposite ends a major axis of said syringe barrel cross-section serving to operably flex the elliptical cross-section of said syringe body into a more circular cross-sectional configuration and increasing the volume of said syringe barrel body and concomitantly serving to create a relative vacuum within said syringe body as compared with the configuration of said syringe tubular, barrel body prior to application of said compression. | 2015-11-19 |
20150328408 | FOLDABLE FINGER FLANGE FOR A SYRINGE - A conventional syringe includes a syringe barrel having a syringe barrel flange laterally extending from an open proximal end of the syringe barrel and a syringe plunger for advancement into the syringe barrel through the open proximal end. A foldable finger flange for such a syringe comprises an attachment member configured to be removably mounted onto the syringe barrel flange, and a flange member pivotably attached to the attachment member. At least a portion of the flange member is pivotable between a use position, wherein said portion of the flange member extends generally perpendicular to the syringe barrel, thereby providing a flange having a greater extent than the syringe barrel flange, and a non-use position, wherein said portion of the flange member does not extend generally perpendicular to the syringe barrel. | 2015-11-19 |
20150328409 | QUANTITATIVE SYRINGE-TYPE EJECTOR - A quantitative syringe-type ejector capable of ejecting the contents packed in one syringe in small quantities is provided. The quantitative syringe-type ejector includes a syringe and a plunger. The plunger includes a piston holding member and a plunger operation member. The piston holding member has at least one arm having: a slide projection slidable on an inner peripheral surface of the syringe; and a lock projection to be releasably locked to a back end of the syringe. The plunger operation member has a lock part to be releasably locked to the back end of the syringe. | 2015-11-19 |
20150328410 | INNER HOUSING FOR A DRUG DELIVERY DEVICE - A dose setting mechanism for a drug delivery device is disclosed. The mechanism comprises an outer housing and an inner housing having an external groove. The inner housing guides a driver to dispense a set dose. A dial sleeve is disposed between the outer and inner housing and is rotatably engaged with the inner housing. When a dose is set, the dial sleeve is rotated and translates away from both the outer housing and the inner housing. | 2015-11-19 |
20150328411 | INJECTOR DEVICE - An injector device for the percutaneous injection of fluids, such as medications, is disclosed. The device can have a mobile phone case. The mobile phone case can hold an auto-injector cartridge having a trigger, spring-loaded needle and reservoir holding a medication such as epinephrine or insulin. The device mobile phone case can communicate injection data to the phone. The phone can communicate the injection data to an emergency service provider. | 2015-11-19 |
20150328412 | Pen Needle Assembly - A pen needle is provided with a plastic non-patient end. Since the non-patient end needle does not contact the patient, the needle can be formed with a larger diameter, permitting more secure attachment to a medication pen and greater medication flow from the cartridge through the cannula. In addition, a two-part hub construction comprising a needle bearing sub assembly and an adapter for attachment to the pen body may be used to lower materials volume and costs, and reduce sharps disposal. In embodiments, a hub according to the invention may be provided with a shield that provides an audible and/or tactile indication when full penetration depth of the needle is achieved. Windows on the shield may reveal a color band on the hub at the full-penetration depth position to provide the user with a visual indication that the pen needle has been used. | 2015-11-19 |
20150328413 | BIOMEDICAL AURAL DELIVERY SYSTEMS AND METHODS - Inner ear treatment delivery devices and methods are disclosed. The device includes a pressurized container filled with a content, a control mechanism within the pressurized container, a nozzle coupled to the control valve, a microprocessor adapted to operate the control valve, and a power source providing energy to the device. The device administers at least one dose of the content to a patient's inner ear. | 2015-11-19 |
20150328414 | INHALATION THERAPY DEVICE COMPRISING A VALVE - The inhalation therapy device according to the invention comprises a nebulizer chamber which accommodates an aerosol generator that emits aerosol into the nebulizer chamber. A valve that has a valve seat, a resilient valve member and a valve member positioning means is arranged at an opening of the nebulizer chamber. The valve member positioning means can be moved out of a first position and into a second position so as to position the valve member on the valve seat in such a manner that in the first position, the valve member, in a flow-free state, is positioned on the valve seat in a pre-tensioned manner and in a second position, is spaced apart from the valve seat. | 2015-11-19 |
20150328415 | CARTRIDGE VAPORIZER IN A PERSONAL VAPORIZER UNIT - A personal vaporizing unit (PVU) generates a vapor that is inhaled by a user. A substance (e.g. liquid) in a cartridge is vaporized or atomized by a heating element that heats the liquid. When the PVU is activated, and the user provides suction, the liquid to be vaporized is drawn out of the cartridge, through a wick, and is atomized by the wick into a cavity containing the heating element. The cartridge may be removable and utilize different connectors for connecting with the PVU. A seal may be used for the liquid reservoir that can be punctured upon usage. | 2015-11-19 |
20150328416 | Device to Meter Fluid - An apparatus for metering the delivery of a fluid. The apparatus has a variable acoustic source and a microphone, both acoustically coupled to a volume having a fluid region and an air region. The apparatus may also include a processor to determine a volume of the air region based on signals received from the microphone and the variable acoustic source. A fluid valve is coupled to the processor, and is configured to allow an amount of fluid to exit the fluid region associated with the volume of the air region. | 2015-11-19 |
20150328417 | VENTILATION SYSTEM - A respiration device ( | 2015-11-19 |
20150328418 | IMPELLER AND MOTOR ASSEMBLY - A breathing assistance apparatus has a pressurised gases source featuring a lightweight impeller with a plastic shaft. The impeller is shroudless. The plastic shaft is supported within the stator by a bearing structure. A resilient motor mount couples the stator and the housing and provide compliance and/or damping for the motor. | 2015-11-19 |
20150328419 | INSPIRATORY PRESSURE CONTROL IN VOLUME MODE VENTILATION - The present disclosure pertains to a mechanical ventilator system configured to deliver a pressurized flow of breathable gas to the airway of a subject. The system is configured to generate the pressurized flow of breathable gas according to a volume control mode therapy regime that delivers a target tidal volume to the subject during inhalation. During an individual inhalation, the system is configured to determine and/or adjust an inspiratory pressure level of the pressurized flow of breathable gas of the volume control mode therapy regime. The inspiratory pressure level is adjusted such that during the inhalation the inspiratory pressure level is not reduced to impede respiratory effort by the subject responsive to the target tidal volume being exceeded during the inhalation. The system comprises one or more of a pressure generator, a subject interface, one or more sensors, one or more processors, a user interface, electronic storage, and/or other components. | 2015-11-19 |
20150328420 | Device and Method for Dilating an Airway Stenosis - A medical device and a system and for dilating a stenotic airway of a patient are described. The medical device comprises a proximal end, a distal end, and a shaft system having an inflation lumen and a ventilation lumen the proximal end. The shaft system has a proximal shaft section and a distal shaft section. An inflatable balloon is attached to the distal shaft section in a position that is proximal to the distal end. The ventilating tip is distal to the balloon on the distal shaft section and has one or more radially facing openings. A method for treating a stenotic airway includes inserting the medical device into a patient's airway, and dilating and ventilating the airway. | 2015-11-19 |
20150328421 | VALSALVA MASK - An interface for positive pressure therapy includes a mask assembly and a headgear assembly. The mask assembly comprises a mask seal that is adapted to underlie the nose. The mask seal extends up the lateral sides of the nose. The mask seal has a primary seal below the nose and a secondary seal alongside the nose. | 2015-11-19 |
20150328422 | MOTION STABILIZER SYSTEM FOR RESPIRATORY INTERFACE DEVICE - A floatable coupling between a patient interface device and a frame body is provided. The floatable coupling includes a number of elastic bands extending between the patient interface device and the frame body. The elastic bands couple the patient interface device and the frame body in a manner that allows the patient interface device to float relative to the frame body. | 2015-11-19 |
20150328423 | NASAL SEAL AND RESPIRATORY INTERFACE - A nasal seal for a respiratory interface comprises a supple lower-nose-receiving center part having a concave shape pre-formed to receive and sealingly contact the tip, lower sides, and base of the nose and sealingly contact the upper lip, and position an aperture for gas flow beneath the nares of wearer. The seal may have resilience or memory towards this preformed shape. | 2015-11-19 |
20150328424 | BREATHING ASSISTANCE APPARATUS - Headgear for use with a respiratory mask is described. The headgear comprises a continuous and substantially curved elongate member extending in use below a user's nose and at least two headgear straps capable of attachment to the ends of the elongate member. A mask attachment on the elongate member is disposed to sit below or on one of said user's nose, mouth, upper lip and an inlet to the mask. The attachment is capable of receiving the mask. | 2015-11-19 |
20150328425 | PATIENT INTERFACE SYSTEMS - A patient interface system for delivering a flow of breathable gas to a patient includes a patient interface structure configured to sealingly engage the face of the patient and a retaining element configured for application to the patient. The retaining element is configured to support the patient interface structure in sealing engagement with the face of the patient. The retaining element includes an adhesive and/or at least one strap. In addition, the patient interface structure is configured to be released from and re-engaged with the retaining element for re-positioning of the patient interface structure relative to the patient's face in a plurality of positions while the retaining element remains supported by the patient. | 2015-11-19 |
20150328426 | GAS FLOW REVERSING ELEMENT - A gas flow reversing element is provided comprising a main piece defining at least one closable outlet opening, a branching piece extending from the main piece, a line connector connected to the distal end of the branching piece, a pressure connector connected to the main piece, the pressure connector being structured to be fluidly connected to a pressurized gas supply; and a nozzle being configured and arranged in the main piece in such a way that a gas flow flowing in the main piece from the pressure connector through the nozzle to the at least one outlet opening, with the at least one outlet opening being disposed in the second open position, a gas flow can also be generated in the branching piece in a direction toward the at least one outlet opening. | 2015-11-19 |
20150328427 | PULSE-WIDTH MODULATION METHOD FOR CONTROLLING OXYGEN CONCENTRATION IN ANESTHETIC MACHINE OR VENTILATOR - A pulse-width modulation method for controlling oxygen concentration in an anesthetic machine or in a ventilator, comprising the following steps: step A, with a predetermined time interval as one pulse interval, a processing unit divides a breathing cycle into multiple consecutive pulse intervals; step B, a data calculation unit calculates the average inspiratory flow in a certain time interval on the basis of inspiratory flows in one cycle that are detected by a detecting unit, and then calculates the average oxygen flow of this stage on the basis of the average inspiratory flow; and, step C, a control unit selects a solenoid valve and controls the opening and closing times thereof on the basis of the average oxygen flow as calculated in the previous step to implement control of the oxygen flow for each interval. | 2015-11-19 |
20150328428 | PERSONAL AIR FILTRATION DEVICE - A personal air filtration device and methods of using the same for providing a zone of filtered air proximate a breathing zone of a user are described. A blower provides an air flow to a head support which delivers the air flow to a zone proximate the users head. The air flow passes through a filter. The filter can be a point of delivery filter disposed about an air permeable surface of the head support. The delivered air flow can provide a laminar air flow defining a zone of filtered air about the user's breathing zone. | 2015-11-19 |
20150328429 | Systems And Methods For Indicating Lifetime Of An NO2-to-NO Reactor Cartridge Used To Deliver NO For Inhalation Therapy To A Patient - The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO | 2015-11-19 |